Irvine, Calif., Aug. 25, 2020 A new study finds women with diabetes and significant levels of calcium in their coronary arteries have higher rates of death from cardiovascular disease and all causes than their male counterparts.
Published in the American Diabetes Association journal,Diabetes Care,researchers from the University of California, Irvine School of Medicine and Cedars-Sinai Medical Center compared the sex-specific impact of coronary artery calcium (CAC) levels in adults with diabetes.CAC was used to predict cardiovascular and all-cause mortality in patients with diabetes. The results of this comparison showed greater CAC predicts cardiovascular and total mortality more strongly in women.
We showed that coronary calcium scores of greater than 100 in a woman with diabetes was associated with higher death rates from cardiovascular diseases and all causes than similar calcium scores in women than in man with diabetes, saidNathan D.Wong, PhD, professor and director for UCIs Heart Disease Prevention Program, and the lead author for the study.
Wongand colleagues studied 4,503 adults with diabetes from a national registry of patients who received coronary calcium heart scans from computed tomography and were followed for causes of death over more than 11 years. Death rates from cardiovascular disease in those who had coronary calcium scores of 101-400 or more, were approximately twice as high in women compared to men. Total death rates in these patients were also higher in women than in men. In analyses adjusted for age and other potential confounders, compared to those with calcium scores of 0, women who had calcium scores of 101-400 and 401 or greater had cardiovascular deaths that were 3.7 and 6.3-fold greater, respectively, compared to men whose risks were 1.6 and 3.5-fold greater, respectively.
Our findings, showing significant levels of coronary calcium to predict mortality from cardiovascular causes more strongly in women than men with diabetes, might also help to explain the poorer prognosis for cardiovascular disease that has been observed for decades in women compared to men with diabetes, saidWong.
Conversely, very low death rates from coronary heart disease and cardiovascular disease seen in those with diabetes who had negative scans (calcium scores of 0), comprising 39 percent of women and 20 percent of men in our study, underscore the point that not all persons with diabetes are risk equivalents for cardiovascular disease, as has been the common belief for decades, noted Cedars-Sinai Medical CentersDaniel Berman, MD, senior author of the study.
Our findings suggest a call-to-action for even more aggressive risk factor management in a woman with diabetes found to have significant levels of coronary calcium to prevent future death from cardiovascular causes saidWong. Previous research conducted byWongand colleagues, has shown rates of cardiovascular disease to be 60 percent lower in those who are well-controlled for blood sugar, cholesterol, and blood pressure.
The study population was part of the CAC Consortium, directed byMichael Joseph Blaha, MD, MPH, from Johns Hopkins School of Medicine. UCIs Amber Cordola-Hsu, PhD, co-led the study withWong.
This study was funded in part by the National Institutes of Health and the American Heart Association.
About the UCI School of Medicine: Each year, the UCI School of Medicine educates more than 400 medical students, and nearly 150 doctoral and masters students. More than 700 residents and fellows are trained at UCI Medical Center and affiliated institutions. The School of Medicine offers an MD; a dual MD/PhD medical scientist training program; and PhDs and masters degrees in anatomy and neurobiology, biomedical sciences, genetic counseling, epidemiology, environmental health sciences, pathology, pharmacology, physiology and biophysics, and translational sciences. Medical students also may pursue an MD/MBA, an MD/masters in public health, or an MD/masters degree through one of three mission-based programs: the Health Education to Advance Leaders in Integrative Medicine (HEAL-IM), the Leadership Education to Advance Diversity-African, Black and Caribbean (LEAD-ABC), and the Program in Medical Education for the Latino Community (PRIME-LC). The UCI School of Medicine is accredited by the Liaison Committee on Medical Accreditation and ranks among the top 50 nationwide for research. For more information, visitsom.uci.edu.
About the University of California, Irvine: Founded in 1965, UCI is the youngest member of the prestigious Association of American Universities. The campus has produced three Nobel laureates and is known for its academic achievement, premier research, innovation and anteater mascot. Led by Chancellor Howard Gillman, UCI has more than 36,000 students and offers 222 degree programs. It is located in one of the worlds safest and most economically vibrant communities and is Orange Countys second-largest employer, contributing $5 billion annually to the local economy. For more on UCI, visit http://www.uci.edu.
Media access: Radio programs/stations may, for a fee, use an on-campus ISDN line to interview UCI faculty and experts, subject to availability and university approval. For more UCI news, visit news.uci.edu. Additional resources for journalists may be found at communications.uci.edu/for-journalists.
Here is the original post:
Women with diabetes and high levels of coronary artery calcium at greater risk of death than men - UCI News
- This 'itchy' symptom is an early sign of diabetes that people often miss; know more about it - The Times of India - February 7th, 2025
- Diabetes and obesity drugs fuel Eli Lilly profit in the final quarter of 2024 - ABC News - February 7th, 2025
- Incidence of type 2 diabetes and metabolic syndrome by Occupation 10-Year follow-up of the Gutenberg Health Study - BMC Public Health - February 7th, 2025
- Abbotts Above the Bias Film Reveals Misconceptions Can Impact Diabetes Care - MultiVu - February 7th, 2025
- Q&A: Diabetes care for the aging population in the digital age - Medical Xpress - February 7th, 2025
- The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes - Nature.com - February 7th, 2025
- Nanoparticle Therapy has Potential to Reprogram the Immune System in Type 1 Diabetes - Managed Healthcare Executive - February 7th, 2025
- Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study - BMC Public Health - February 7th, 2025
- Assessing type-2 diabetes risk based on the Indian diabetes risk score among adults aged 45 and above in India - Nature.com - February 7th, 2025
- Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes - Nature.com - February 7th, 2025
- Sugary Drinks Fuel Millions of Diabetes and CVD Cases - Medscape - February 7th, 2025
- 1 in 5 UK adults estimated to have diabetes in new record high - Euronews - February 7th, 2025
- New, increasingly widely used diabetes medication may have additional health benefits for older adults - Medical Xpress - February 7th, 2025
- Patients using diabetes apps can miss critical alerts. Heres how to make sure youre getting them - Canon City Daily Record - February 7th, 2025
- Diabetes and obesity drugs fuel Eli Lilly profit in the final quarter of 2024 - News-Press Now - February 7th, 2025
- Does wearing a continuous glucose monitor help people without diabetes? We asked experts. - Popular Science - February 7th, 2025
- What is prediabetes and what can you do to stop it? - The Independent - February 7th, 2025
- Diabetes symptoms: 6 high blood sugar warning signs that show on hand and feet - India.com - February 7th, 2025
- The #1 Habit for Better Heart Health If You Have Diabetes, According to Experts - EatingWell - February 7th, 2025
- 'Fix Broken Food System!' Government Urged as Study Says 1 in 5 Brits Affected by Diabetes - Men's Health UK - February 7th, 2025
- World Diabetes Day 2024 - World Health Organization (WHO) - December 6th, 2024
- The WHO Global Diabetes Compact - December 6th, 2024
- Diabetes - World Health Organization (WHO) - December 6th, 2024
- Kumamoto University researchers discover groundbreaking antidiabetic compound - EurekAlert - December 6th, 2024
- Med's David Kaelber comments on GLP-1 agonists, which provide benefits like managing diabetes and weight loss - The Daily | Case Western Reserve... - December 6th, 2024
- Jordan Chiles Is On a Mission To Raise Awareness for Early Type 1 Diabetes Screening - Verywell Health - December 6th, 2024
- There's A Tasty Food That May Reduce Your Risk Of Developing Type 2 Diabetes, Study Shows - HuffPost - December 6th, 2024
- Empagliflozin Linked to Lower Risk of Diabetic Retinopathy Progression - Medpage Today - December 6th, 2024
- GLP-1 Medications Associated with Reduced Likelihood of Dementia Compared to Other Diabetic Meds - Epic Research - December 6th, 2024
- Sanders Slams Greed That Led to Surge in Obesity, Diabetes in US - The Well News - December 6th, 2024
- Eli Lilly to Expand Facility to Meet Demand for Diabetes, Obesity Treatments - The Wall Street Journal - December 6th, 2024
- New Study Teases Out Chocolate and Diabetes Connection - Medpage Today - December 6th, 2024
- Diabetes tool turned wellness trend: Is a glucose monitor right for you? - KARE11.com - December 6th, 2024
- Reporter doesnt have diabetes but wore a glucose monitor anyway. Here's what she learned - CNN - December 6th, 2024
- Lilly's Zepbound (tirzepatide) superior to Wegovy (semaglutide) in head-to-head trial showing an average weight loss of 20.2% vs. 13.7% - Investors |... - December 6th, 2024
- I dont have diabetes, but I wore a glucose monitor for six weeks. Heres what I learned about food (and anxiety) - CNN - December 6th, 2024
- Higher niacin levels linked to lower cardiovascular risk, but not in those with diabetes - Healio - December 6th, 2024
- This Type Of Chocolate Could Reduce Type 2 Diabetes Risk By 21% - NDTV - December 6th, 2024
- New Study Links Safer BPA Alternatives to Obesity, Diabetes, and Hormone Disruption - SciTechDaily - December 6th, 2024
- Turns Out Dark Chocolate Has a Health Benefit That's Shockingly GreatAnd Totally Unexpected - Well+Good - December 6th, 2024
- Global report on diabetes - World Health Organization (WHO) - October 22nd, 2024
- Ultra-processed food may be particularly harmful for people with diabetes, scientists warn - The Independent - October 22nd, 2024
- New drugs may be able to treat multiple problems beyond diabetes - The Straits Times - October 22nd, 2024
- Best Fruits for Diabetes (and What To Avoid) - Health Essentials - October 22nd, 2024
- Cutting Sugar May Reduce Your Diabetes, Stroke, and Depression Risk - Healthline - October 22nd, 2024
- Can Diabetes Care Teams Improve Patient Outcomes and Value? - Medscape - October 22nd, 2024
- Oral Semaglutide Reduces MACE Risk in People With Type 2 Diabetes and CVD - MD Magazine - October 22nd, 2024
- High expression of CNOT6L contributes to the negative development of type 2 diabetes - Nature.com - October 22nd, 2024
- Recent Advances and Therapeutic Benefits of Glucagon-Like Peptide-1 (GLP-1) Agonists in the Management of Type 2 Diabetes and Associated Metabolic... - October 22nd, 2024
- Dental teams could detect undiagnosed diabetes in more than one million people with new care pathway - Nature.com - October 22nd, 2024
- Groundbreaking Innovations in Diabetes Care: Highlights from the 2024 Diabetes Technology Meeting - Beyond Type 1 - October 22nd, 2024
- COVID-19 linked to type 2 diabetes onset in children - Medical Xpress - October 22nd, 2024
- The effect of adding pancreatin to standard otilinium bromide and simethicone treatment in type 2 diabetes mellitus patients with irritable bowel... - October 22nd, 2024
- Does microdosing Ozempic work? What experts are saying about the diabetes drug also used for weight loss - Medical Xpress - October 22nd, 2024
- The Link between GLP-1 Drugs and Diabetic Retinopathy Is Not So Clear | AAO 2024 - Managed Healthcare Executive - October 22nd, 2024
- The overexpression of human amylin in pancreatic cells facilitate the appearance of amylin aggregates in the kidney contributing to diabetic... - October 22nd, 2024
- RNAO releases updated guidelines for diabetic foot ulcer care - Benefits and Pensions Monitor - October 22nd, 2024
- COVID-19 raises the risk of type 2 diabetes in children, study reveals - News-Medical.Net - October 22nd, 2024
- Semaglutide: What impact does it really have on heart health? - Medical News Today - October 22nd, 2024
- Glucose monitors for diabetes have finally been funded but a chronic workforce shortage will limit the benefits - The Conversation - October 22nd, 2024
- Early vs Late Fast Window: Is One More Effective? - Medscape - September 13th, 2024
- Breakthrough T1D Walk to Cure Type 1 Diabetes - KATU - September 13th, 2024
- Foods That May Increase Kids' Risk of Type 1 Diabetes Revealed - Newsweek - September 13th, 2024
- Beds and Herts patients to be re-tested in diabetes results error - BBC.com - September 13th, 2024
- This common habit increases your diabetes risk by 50%; Heres how to fix it - The Economic Times - September 13th, 2024
- Elevated risk of pre-diabetes and diabetes in people with past history of COVID-19 in northeastern Nigeria - BMC Public Health - September 13th, 2024
- Study links bananas, oats and yoghurt to greater diabetes risk in susceptible children - The Guardian - September 13th, 2024
- Could the Norton research teams studying diabetes and Alzheimer's come up with a cure? - Courier Journal - September 13th, 2024
- Weight loss, better beta-cell function tied to long-term glycemic control with tirzepatide - Healio - September 13th, 2024
- Study finds weekly insulin injections as effective for diabetes as daily shots - UPI News - September 13th, 2024
- Ozempic, Wegovy, Rybelsus: Are we losing sight of overall health? Heres what the science says - The Conversation - September 13th, 2024
- With once-a-week dosing, insulin efsitora alfa delivers similar A1C reduction compared to daily insulin in adults with type 1 diabetes - PR Newswire - September 13th, 2024
- Dining with Diabetes workshops offered - The Courier-Express - September 13th, 2024
- Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing - News-Medical.Net - September 13th, 2024
- The menopause can increase your likelihood of developing heart disease, type 2 diabetes and hypertension but exercise can help lower risk - The... - September 13th, 2024
- Artificial pancreas shows promise in people with type 1 diabetes on kidney dialysis - MSN - September 13th, 2024
- How an Indian executive battled flesh-eating disease and diabetes, and won - South China Morning Post - September 13th, 2024
- India brings early Diabetic Retinopathy detection to the last mile with Artificial Intelligence - PR Newswire - September 13th, 2024
- Why this diabetes drug may be the answer to NASA search for radiation protection - Texas Public Radio - September 13th, 2024
- The National Association of Chain Drug Stores and the American Diabetes Association Promote Nutrition Security and its Role in Preventing and Managing... - September 13th, 2024