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Pemphigus is a disease that causes blistering of the skin and the inside of the mouth, nose, throat, eyes, and genitals. The disease is rare in the United States.

Pemphigus is anautoimmune diseasein which the immune system mistakenly attacks cells in the top layer of the skin (epidermis) and the mucous membranes. People with the disease produce antibodies against desmogleins, proteins that bind skin cells to one another, and less commonly other proteins in the skin. When these bonds are disrupted, skin becomes fragile, and fluid can collect between its layers, forming blisters.

There are several types of pemphigus, but the two main ones are:

There is no cure for pemphigus, but in many cases, it is controllable with medications.

See the article here:
What is Pemphigus? Symptoms & Causes | NIAMS

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This entry was posted on February 7, 2025 at 2:54 am and is filed under Immune System. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed. |