The Skin The skin is obviously a physical barrier to many germs and toxins, as it contains special immune cells called Langerhans cells that act as warning bells to alert the immune system to any foreign agents. Langerhans cells also regulate the immune response to these agents, evident in the skins reaction to stinging nettles or a cat scratch. The skin also secretes antibacterial substances which hinder the growth of bugs on our skin.
The Mucus Membrane Linings - The eyes, nose, and mouth are all possible ports of entry for invading germs, but our tears, nasal secretions, and saliva all contain enzymes or cells of the immune system to keep the invaders at bay. The mucus membrane linings of the respiratory, gastrointestinal, and genitourinary tracts also provide one of the first lines of defense against invasion by microbes or parasites.
Close
If the germs make it past this first line of defense, they encounter a number of immune components inside the body including:
The Lymphatic or Lymph System The swollen glands that we all check for in the neck are in fact lymph nodes that are part of the lymphatic system. The lymph system is similar to the circulatory system, in that it is an interconnected series of vessels carrying lymphatic fluid, except that lymphatic fluid is not pumped around the body (like the heart pumps blood), but rather it moves passively. Fluid oozes in and out of the lymphatic system with normal body and muscle movement. Lymph contains plasma (the watery part of the blood) and helps to carry nutrients, oxygen, and waste products from the blood cells through the capillary walls. Germs generally find their way into this fluid and are then carried to the lymph nodes, which act as filters. The lymph nodes filter the fluid, and if there are any germs, the immune cells in the node rise to the occasion to fight them off. If the lymph nodes swell up during this process, this acts as a sure indication of infection. The filtered lymphatic fluid is then returned to the blood stream where the cycle starts again.
The Thymus Gland The thymus gland is situated in the chest in front of the heart but behind the breast bone, and is responsible for producing T-cells, one of the important germ-fighting cells of the immune system. The thymus gland is very important for newborn babies (who need it to survive), but as we get older it becomes less important, as other parts of our immune system manage to compensate.
Bone Marrow All the cells of the immune system are originally derived from the bone marrow. Our bone marrow produces blood cells both red cells, which carry oxygen, as well as white blood cells, which are part of the immune system. There are many different types of white blood cells including T-cells, B-cells, natural killer cells, lymphocytes, etc. and they all work together to destroy the foreign cells or germs. The B-cells produce antibodies, or proteins that are specific to the germ (or antigen, which is anything foreign to the body) encountered. Specific B-cells are tuned into specific germs, and when that germ is present, the corresponding B-cell multiplies rapidly and produces the antibodies to destroy that germ. The antibodies then bind to the germ and prevent it from entering our cells. If this is not enough, the antibodies will cover the germ and signal the complement system for assistance.
The Spleen
The spleen is also an important filtration organ, as it searches for and filters out foreign cells as well as old red blood cells that need replacing. In addition, the spleen plays an important role in activating appropriate immune responses by presenting the antigen to the appropriate T or B cells, which in turn can then produce large amounts of anti-bodies.
White blood cells or leukocytes Immune cells are white blood cells, otherwise known as leukocytes, which are produced in large quantities in the bone marrow. There is a great variety of leukocytes, each with a specific function and role to play in the working of the immune system. Some of these blood cells seek out and destroy foreign organisms, some dispose of infected or mutated body cells, while others release proteins called antibodies that alert other cells to destroy invading organisms.
Antibodies Antibodies are Y-shaped proteins found in the blood and are made by B-cells. Essentially these proteins are used by the immune system to identify and block the effects of antigens. Thus when an antigen (or foreign cell) is identified, an antibody attaches itself - like a key fits into a lock and neutralizes the effect of the antigen.
The Complement system The complement system is a series of different proteins that work with (or compliment) the antibodies. These proteins flow freely in the blood and can therefore rapidly reach the site of an invasion where they can react directly with antigens (molecules that the body recognizes as foreign and potentially dangerous). When triggered, these complement proteins can trigger inflammation, attract eater cells such as macrophages to the area, cover intruders so that eater cells are more likely to destroy them, and directly kill intruders by causing the cells to burst. This in turn signals other clean up cells, called phagocytes to come and remove the burst cell. Other substances such as hormones, tumor necrosis factor, and interferons also play an integral part in the functioning of the immune system.
Close
Originally posted here:
The Immune System and Immune Disorders - NativeRemedies
- A mathematical model simulating the adaptive immune response in various vaccines and vaccination strategies - Nature.com - October 14th, 2024
- Fox Chase Cancer Center Researchers Find Gene That Triggers Immune Response in Treatment-Resistant Small-Cell Lung Cancer - Fox Chase Cancer Center - October 14th, 2024
- What Does It Mean to Be Immunocompromised? - The New York Times - October 14th, 2024
- Scientist hopes to cure Type 1 diabetes by disguising stem cells - The University of Arizona - October 14th, 2024
- Watching an infection unfold with a sphingolipid probe - Drug Discovery News - October 14th, 2024
- The cells that protect your brain against infection could also be behind some chronic diseases - BBC.com - October 14th, 2024
- On Nutrition: Foods that help strengthen the immune system - LimaOhio.com - October 14th, 2024
- An integral T cell pathway has implications for understanding sex-based immune response - Medical Xpress - October 14th, 2024
- Immune Response Linked to Lewy Body Formation - Neuroscience News - October 14th, 2024
- Are vaccines the future of cancer prevention? - Genetic Literacy Project - October 14th, 2024
- The Gut Microbiome and Autoimmunity - Inside Precision Medicine - October 14th, 2024
- Researchers discover how oral cancer cells may block the body's immune response - News-Medical.Net - September 21st, 2024
- Are Vaccines More Effective When You Believe in Them? - Greater Good Science Center at UC Berkeley - September 21st, 2024
- Researchers discover immune response to dengue can predict risk of severe reinfections - Medical Xpress - September 21st, 2024
- Texas Researchers Find Acid Walls That Shield Cancer Tumors from Bodys Immune System Response - DARKDaily.com - Laboratory News - September 21st, 2024
- Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis - Nature.com - September 21st, 2024
- A new way to reprogram immune cells and direct them toward anti-tumor immunity - MIT News - September 21st, 2024
- Unravelling the many mysteries of the immune system - Cosmos - September 21st, 2024
- Long COVID patients maintain robust immune memory two years after infection - News-Medical.Net - September 21st, 2024
- Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other viral infections - Journal of... - September 21st, 2024
- Which adults benefit from the pneumococcal vaccine? - Mayo Clinic Press - September 21st, 2024
- UAMS receives $2.2 million grant to study immune response to eye disease - talkbusiness.net - September 21st, 2024
- Low oxygen levels in tumors could enhance some of the body's immune responses against cancer - Medical Xpress - September 21st, 2024
- Overview of the Immune System - The Merck Manuals - March 18th, 2024
- What are the organs of the immune system? - InformedHealth.org - NCBI ... - January 17th, 2024
- Mom who homeschools her children reveals she lets her one-year-old play in and EAT mud - but insists it is goo - Daily Mail - November 26th, 2023
- The limits of nutritional supplements: they dont cure or prevent ailments, nor are they harmless - EL PAS USA - November 26th, 2023
- Here's how your gut affects your mental health, immune function and even cardiovascular health - indulgexpress - November 18th, 2023
- From fear to freedom: Anchor Paul LaGrone shares his story of sudden hair loss & the disease that caused it - ABC Action News Tampa Bay - May 9th, 2023
- Strengthen Your Immune System With 4 Simple Strategies - May 1st, 2023
- Immunodeficiency Awareness Month: What Is The Science Behind These Diseases? Know Warning Signs - ABP Live - May 1st, 2023
- Nearly 90% of patients with rare skin cancer respond to therapy that prevents tumors from evading the immune - cleveland.com - April 23rd, 2023
- University of Cincinnati researchers helping develop 'vaccine' to fight aggressive cancer - WKRC TV Cincinnati - April 23rd, 2023
- Sana Biotechnology Highlights Preclinical Hypoimmune Data for its Allogeneic CAR T Platform and Advancements with its In Vivo Fusogen Platform with... - April 23rd, 2023
- Immune System: Parts & Common Problems - Cleveland Clinic - March 21st, 2023
- Disorders of the Immune System | Johns Hopkins Medicine - March 21st, 2023
- Sometimes 15 Minutes Are More Than Enough To Improve Immune System, Sleep Quality And Depression - Revyuh - March 13th, 2023
- People produce endocannabinoids similar to compounds found in marijuana that are critical to many bodily functions - The Conversation Indonesia - February 24th, 2023
- Spending more time with your kids, grandkidsand their germsmay lower risk of a severe outcome from Covid-19, recent studies show - CNBC - December 20th, 2022
- Published in Journal for Immunotherapy of Cancer: Using Single-Cell Analysis to Assess the Effects of an Anti-OX40 Monoclonal Antibody in Its... - November 17th, 2022
- Man who had COVID-19 for 400 days finally cured after getting treated with antibodies, study says - msnNOW - November 17th, 2022
- Social Distancing: The Impact on Your Health and Immune System - Healthline - October 7th, 2022
- Unraveling the Mysteries of the Immune System - Duke University School of Medicine - October 7th, 2022
- When Will ISR Immune System Regulation Holding AB (publ) (STO:ISR) Become Profitable? - Simply Wall St - October 7th, 2022
- VitaGaming Introduces Immune Support and Collagen to help Gamers boost immunity and fight stress - PR Web - October 7th, 2022
- Ohio reports third U.S. death of person with monkeypox who had underlying health conditions - CNBC - October 7th, 2022
- How a select few people have been cured of HIV - PBS - October 7th, 2022
- BeniCaros Wins Nutrition Industry Executive 2022 Immune Health Award - GlobeNewswire - October 7th, 2022
- Seasonal superfoods to give your immune system a boost this autumn - Yahoo Entertainment - October 7th, 2022
- Whats Going Around: Flu cases confirmed locally - ABC27 - October 7th, 2022
- Contributor: How to Fight the Cold and the Flu This Season - AJMC.com Managed Markets Network - October 7th, 2022
- Updated COVID-19 Bivalent Booster Released in Time for Fall and Winter Omicron Wave - Cornell University The Cornell Daily Sun - October 7th, 2022
- Oralair pill that retrains the immune system to reduce risk of thunderstorm asthma - 7NEWS - October 7th, 2022
- COVID immune reaction could affect brain mechanisms and induce neurological symptoms - Sky News - October 7th, 2022
- 7 Surprising Health Benefits of Pumpkins - AARP - October 7th, 2022
- Why Do Some Allergies Go Away While Others Dont? - The Atlantic - October 7th, 2022
- 15 foods to boost the immune system - Medical News Today - September 4th, 2022
- The powerful supplement that could enhance your immune response to bacteria and viruses - Express - September 4th, 2022
- New research: Cancer-fighting viruses can boost body's immune response - The Indian Express - September 4th, 2022
- Long COVID: How researchers are zeroing in on the self-targeted immune attacks that may lurk behind it - The Conversation Indonesia - September 4th, 2022
- Study raises concerns about the effectiveness of the monkeypox vaccine - STAT - September 4th, 2022
- Five Natural Immune-Boosting Treatments to Try This Flu Season - Boston magazine - September 4th, 2022
- Returning to Football After COVID-19 Infection - Louisiana State University - September 4th, 2022
- #1 Best Way to Boost Your Immunity Against BA.5 Eat This Not That - Eat This, Not That - September 4th, 2022
- Whatever happened to the Botswana scientist who identified omicron then caught it? - NPR - September 4th, 2022
- Non-Hodgkin's lymphoma: What is the cancer that Jane Fonda announced she has? - FOX 29 Philadelphia - September 4th, 2022
- 8 Health Benefits of Cabbage - Health Essentials - September 4th, 2022
- Identification of cervical squamous cell carcinoma feature genes and construction of a prognostic model based on immune-related features - BMC Women's... - September 4th, 2022
- VICTOR DAVIS HANSON: The mysteries of Long COVID - Las Vegas Review-Journal - September 4th, 2022
- Is This Popular Montana City The Most Depressed In The Nation? - XL Country - September 4th, 2022
- First adapted COVID-19 booster vaccines recommended for approval in the EU | European Medicines Agency - European Medicines Agency | - September 4th, 2022
- Potential of Vaccines in Treating Parkinson's, Alzheimer's Detailed | AC Immune to Launch Trial of Vaccine in Early-stage Parkinson's - Parkinson's... - September 4th, 2022
- What Are Zombie Cells? Here's How They Impact Aging - Prevention Magazine - September 4th, 2022
- What To Know About Hand, Foot and Mouth Disease - Health Essentials - September 4th, 2022
- On maternity and the stronger immune response in women - Nature.com - August 19th, 2022
- New study could change what we eat to supercharge immune system and fight disease - WOODTV.com - August 19th, 2022
- Extending dogs' lives, and sex and the immune system - MIT Technology Review - August 19th, 2022
- Your Immune System Will Thrive With This Elderberry Hill Liquid Morning Multivitamin - Men's Journal - August 19th, 2022
- Sure Signs Your Immune System Isn't as Strong as it Should Be Eat This Not That - Eat This, Not That - August 19th, 2022
- Can the monkeypox vaccine stop the current outbreak? : Goats and Soda - NPR - August 19th, 2022