Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body. Lupus occurs when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation, and in some cases permanent tissue damage, which can be widespread affecting the skin, joints, heart, lung, kidneys, circulating blood cells, and brain.
If you have lupus, you may experience periods of illness (flares) and periods of wellness (remission). Lupus flares can be mild to serious, and they are unpredictable. However, with treatment, many people with lupus can manage the disease.
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Systemic Lupus Erythematosus (Lupus) - Who gets it? | NIAMS
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