Heart cells created from human embryonic stem cells successfully restored damaged heart muscles in monkeys.
The results of the experiment appear in the April 30 advanced online edition of the journal Nature in a paper titled, "Human embryonic-stem cell derived cardiomyocytes regenerate non-human primate hearts."
The findings suggest that the approach should be feasible in humans, the researchers said.
"Before this study, it was not known if it is possible to produce sufficient numbers of these cells and successfully use them to remuscularize damaged hearts in a large animal whose heart size and physiology is similar to that of the human heart," said Dr. Charles Murry, UW professor of pathology and bioengineering, who led the research team that conducted the experiment.
A physician/scientist, Murry directs the UW Center for Cardiovascular Biology and is a UW Medicine pathologist.
Murry said he expected the approach could be ready for clinical trials in humans within four years.
In the study, Murry, along with Dr. Michael Laflamme and other colleagues at the UW Institute for Stem Cell & Regenerative Medicine, experimentally induced controlled myocardial infarctions, a form of heart attack, in anesthetized pigtail macaques.
The infarcts were created by blocking the coronary artery of macaque for 90 minutes, an established model for the study of myocardial infarction in primates.
In humans, myocardial infarctions are typically caused by coronary artery disease. The resulting lack of adequate blood flow can damage heart muscle and other tissues by depriving them of oxygen. Because the infarcted heart muscle does not grow back, myocardial infarction leaves the heart less able to pump blood and often leads to heart failure, a leading cause of cardiovascular death.
The goal of stem cell therapy is to replace the damaged tissue with new heart cells and restore the failing heart to normal function.
See the rest here:
Stem cell therapy regenerates heart muscle damaged from heart attacks in primates
- My Life After MS: Ep 2 part 1-How I Got Pregant - Video - April 19th, 2015
- Telehealth Stem Cell Clinic Now Offering Wound Healing Guarantee - April 13th, 2015
- NYC Health & Longevity Center Now Offering Stem Cell Therapy to Avoid Joint Replacement - April 13th, 2015
- Stem Cell Therapy For Pain - Columbia Pain Management, Hood River OR - Video - April 12th, 2015
- U.S. Stem Cell Clinic: Patient Based Webinar - Video - April 12th, 2015
- Stem Cell Therapy for Pain - Now Available at Columbia Pain Management - Video - April 11th, 2015
- U.S. Stem Cell Clinic: Stem Cell Banking - Video - April 11th, 2015
- U.S. Stem Cell Clinic: What is Stem Cell Therapy? - Video - April 11th, 2015
- U.S. Stem Cell Clinic: How is Stem Cell Therapy Performed? - Video - April 11th, 2015
- Back Pain Stem Cell Therapy Doctors Tampa - Video - April 9th, 2015
- Regeneus hits key stem cell manufacturing milestone - April 9th, 2015
- Dr. Raj at Beverly Hills Orthopedic Institute Now Offering Stem Cell Therapy to Heal Chronic Tendonitis - April 7th, 2015
- Is a loophole in stem cell law helping new therapy to thrive, or allowing dubious science? - April 5th, 2015
- Can PRP and Stem Cell Therapy Help You? | Orlando Orthopaedic Center - Video - April 3rd, 2015
- Orthopedic Stem Cell Therapy for Arthritic Joint Pain - Video - April 3rd, 2015
- Induced Pluripotent Stem Cell (iPSC) Industry Complete Report 2015 - 2016 - April 3rd, 2015
- New study: Stem cell field is infected with hype - March 31st, 2015
- Arizona Pain Stem Cell Institute Now Offering Stem Cell Therapy to Help Patients Avoid Hip and Knee Replacement - March 30th, 2015
- Center of Regenerative Orthopedics in South Florida Now Offering Stem Cell Therapy to Help Avoid Hip and Knee ... - March 30th, 2015
- Ask Dr. Lemper | Stem Cell Therapy Treatments - Video - March 29th, 2015
- On stem cell therapy, benefits - March 26th, 2015
- Stem cell therapy could reverse Type 2 diabetes, UBC study finds - March 24th, 2015
- Nevada Pain Now Offering Stem Cell Therapy to Help Patients Delay or Avoid Joint Replacement - March 23rd, 2015
- Stem Cell Injection Treatment Stem Cell Therapy - Video - March 21st, 2015
- Stem cell therapy and me1 - Video - March 21st, 2015
- stem cell therapy di indonesia Jakarta tangerang serpong bsd bintaro - Video - March 21st, 2015
- Knee arthritis 3 years after stem cell therapy by Harry Adelson, N.D. - Video - March 21st, 2015
- Amniotic Stem Cell Therapy Discussed by R3 (844) GET-STEM - Video - March 19th, 2015
- Stem cell therapy may help treat type 2 diabetes - March 19th, 2015
- CAR T-Cell Therapy - Nebraska Medicine - Video - March 18th, 2015
- Stem Cell Therapy Now Being Offered for NonHealing Wounds at Telehealth's Three Regenerative Medicine Clinics - March 18th, 2015
- Beware stem cell therapy for lung disease - March 17th, 2015
- The New Botox: Stem Cell Therapy Cream Reviews - Video - March 14th, 2015
- Miracle stem cell therapy reverses multiple sclerosis - Video - March 14th, 2015
- Cell Therapy - American Cancer Society - March 14th, 2015
- Hip and shoulder arthritis six months after bone marrow stem cell therapy by Harry Adelson ND - Video - March 13th, 2015
- Stem Cell Research & Therapy | Full text | Amnion-derived ... - March 13th, 2015
- High-Dose Immunosuppressive Therapy and Autologous ... - March 13th, 2015
- Biotech Stock Mailbag: Neuralstem, Genfit, Intercept, Amarin - March 13th, 2015
- UCLA Research Shows Promising Method For Correcting Genetic Code To Treat Sickle Cell Disease - March 12th, 2015
- Stem Cell Therapy Cream - Video - March 9th, 2015
- Hello Doctor - Information about Stem Cell Therapy - [Ep 76] - Video - March 9th, 2015
- Okyanos Stem Cell Therapy Launches Orthopedic Lifestyle Survey - March 9th, 2015
- Alternative Treatments For COPD - FAT STEM CELL THERAPY in Dallas, Texas - Video - March 8th, 2015
- Shoulder Labral Tear Repair Using Stem Cell Therapy - Orthopedic Surgeon, Dr. Wade McKenna - Video - March 7th, 2015
- What Is Stemnexa Stem Cell Therapy For Orthopedics And Is It Safe? - Video - March 7th, 2015
- What Is AlphaGEMS Amniotic Tissue Product And How Does It Augment Bone Marrow Stem Cell Therapy? - Video - March 7th, 2015
- Regenerative Medicine | Graziella Pellegrini - Video - March 7th, 2015
- Regenerative Stem Cell Therapy - Video - March 7th, 2015
- Orthopedic Stem Cell Therapy From Bone Marrow - Video - March 6th, 2015
- Using Stem Cell Therapy to Repair Damaged Tissue from Shoulder Impingement Syndrome - Video - March 6th, 2015
- Overcoming Knee Replacement Surgery Faster Using Amniotic Tissue-Enhanced Stem Cell Therapy - Video - March 6th, 2015
- Stem Cell Therapy for Bone Fractures - Board-Certified Orhopedic Surgeon, Wade McKenna DO - Video - March 6th, 2015
- stem cell therapy helps avoiding knee surgery - Video - March 6th, 2015
- Knee arthritis one year after stem cell therapy by Harry Adelson, N.D. - Video - March 6th, 2015
- Stem Cell Therapy in Osteo Arthritis Knee - Video - March 6th, 2015
- Stem Cell Therapy | Simple way to regrow cartilage - Video - March 6th, 2015
- Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas ... - March 6th, 2015
- Shoulder/Hip torn labrum 2 years and 5 months (respectively) after stem cell therapy by Adelson - Video - March 1st, 2015
- 'Miracle' stem cell therapy reverses multiple sclerosis - March 1st, 2015
- Animal cells for a younger you - February 28th, 2015
- Stem cell therapy a boon to Parkinson's patients - February 26th, 2015
- Stem cell therapy a boon for Parkinson patients - February 26th, 2015
- Rowan Researcher Targets Stem Cell-Based Therapy for Rare Childhood Disease - February 25th, 2015
- Stem Cell Research & Therapy | Full text | Aromatic ... - February 24th, 2015
- Stem Cell Therapy for Liver Failure Cirrhosis Kidney Damage - 6 Months After Stemcell Transplant - Video - February 21st, 2015
- Stem Cell Therapy Using Fat Cells - Howard Beach, Ozone Park, Queens NY - Dr. Benjamin Bieber, MD - Video - February 20th, 2015
- Ryan Benton Discusses Stem Cell Therapy for Duchenne's Muscular Dystrophy - Video - February 20th, 2015
- Stem Cell Therapy Using Bone Marrow - Howard Beach, Ozone Park, Queens NY - Dr. Benjamin Bieber, MD - Video - February 20th, 2015
- Dr Ellis hosts seminar on Stem Cell Therapy & Facial Rejuvenation - Video - February 18th, 2015
- Dr. Raj at Beverly Hills Orthopedic Institute Achieving 80% Success with Stem Cell Therapy - February 17th, 2015
- FAQ Part 1: MEsenchymal Stem cell therapy for CAnadian MS patients (MESCAMS) - Video - February 14th, 2015
- Stem Cell Therapy for Erectile Dysfunction - Alvarado Hospital - Video - February 14th, 2015
- How about Stem Cell Therapy for LBD, Nova Cells Institute stem cells - Video - February 14th, 2015
- Cell Therapy Report 2014-2020 - Technologies, Markets and Companies - February 10th, 2015
- Cell Therapy may have just raised $1M, but will crowdfunding have a lasting place in biotech? - February 10th, 2015
- FAQ Part 4: MEsenchymal Stem cell therapy for CAnadian MS patients (MESCAMS) - Video - February 9th, 2015
- Neck and Shoulder arthritis two years after stem cell therapy by Harry Adelson, N.D. - Video - February 6th, 2015
- Okyanos Cell Therapy Success Brings Hope for a Normal Life - February 5th, 2015
- Florida Panther Receives Cutting Edge Stem Cell Procedure from MediVet Biologics - February 5th, 2015