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Stem-cell op child 'doing well'

July 26th, 2012 2:13 am

25 July 2012 Last updated at 21:04 ET By James Gallagher Health and science reporter, BBC News

The first child to have pioneering surgery to rebuild his windpipe with his own stem cells is doing well and is back in school.

Ciaran Finn-Lynch, who is now 13, had the ground-breaking surgery at London's Great Ormond Street Hospital in 2010.

Using Ciaran's own cells meant his immune system would not reject, and attack, the organ.

His surgeons said things were going well so far and that Ciaran could live the life of a normal teenager.

He was born with long-segment tracheal stenosis, which causes breathing difficulties. His lungs collapsed on the day he was born and he had major surgery to reconstruct his airways when he was six days old.

Metal tubes were used to hold his airways open, but in 2009 one caused huge amounts of bleeding when it damaged the main blood vessel coming out of the heart.

It was at this stage surgeons tried a pioneering operation. Instead of growing a new windpipe, they took a donor windpipe and stripped it of all the donor's cells. What was left was a three-dimensional web of collagen fibres which was transplanted into Ciaran.

Meanwhile, stem cells, which can become any other type of cell, from nerve to skin cells, were taken from Ciaran's bone marrow. These were then sprayed onto the newly transplanted windpipe.

The surgery had been tried once before in Spain, in 2008, on a 30-year-old woman, but Ciaran was the first child.

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Stem-cell op child 'doing well'

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