Conference Series Ltdinvites all the members of Biological Sciences family, from all over the world to join and share research at the10th World Congress on Stem Cell and Biobankingduring 23th& 24thOctober, 2017 at Osaka, Japan, which includes prompt keynote presentations, plenary talks, oral talks, poster presentations and exhibitions.
Theme: Accelerating the Innovative Research &Technology in Stem Cell & Biobanking
Stem Cell Convention 2017aims in proclaim knowledge and share new ideas amongest the professionals, industrialists and students from research area of Stem Cells and Biobanking to share their research experiences and indulge in interactive discussions at the event. This scientific gathering guarantees that offering the thoughts and ideas will enable and secure you the theme Accelerating the Innovative Research &Technology in Stem Cell & Biobanking. Biobanking is the latest trending technology in many fields. The current era fully rolled out with many new Stem cells and Biobanking technologies. In such case more research centres and Hospitals were newly introduced within market which obviously shows the market growth of stem cells and Biobanking techniques. While analyzing the revenue growth of stem cells research, it highly developed from $150 billion USD to $250 billion USD since from 2010-2015. And the annual growth percentage increases from 20-55 percentages.
Track-1
Stem Cells Biology
Stem cellsare undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. They are found in multicellular organisms. In mammals, there are two broad types of stem cells:embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In adult organisms, stem cells andprogenitor cellsact as a repair system for the body, replenishingadult tissues. In a developing embryo, stem cells can differentiate into all the specialized cellsectoderm, endoderm and mesoderm (see induced pluripotent stem cells)but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.Umbilical cord cells are also included in this Stem Cell Research.
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Stem cells technologyis a rapidly developing field that combines the efforts of cell biologists,geneticists, and clinicians and offers hope of effective treatment for a variety of malignant and non-malignant diseases. Stem cells are defined astotipotent progenitor cellscapable of self-renewal and multilineage differentiation. Stem Cell s technologysurvive well and show stable division in culture, making them ideal targets for in vitro manipulation. Although early research has focused on hematopoietic stem cells, stem cells have also been recognised in other sites. Research into solid tissue stem cells has not made the same progress as that on hematopoietic stem cells. This is due to the difficulty of reproducing the necessary and precise three dimensional arrangements and tight cell-cell and cell-extracellular matrix interactions that exist in solid organs. However, the ability of tissue stem cells to integrate into the tissue cytoarchitecture under the control of the host microenvironment and developmental cues makes them ideal for cell replacement therapy. Some of the methods of Stem Cells technology include Cord Stem Cell Transplantation, Allogeneic stem cell transplantation.
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Track-3
Stem Cells Therapy Research
Stem cells therapyis the use of stem cells to treat or prevent a disease or condition.Bone marrow transplantis the most widely used stem-cells therapy, but some therapies derived from umbilical cord blood are also in use. Research is underway to develop various sources forstem cells, and to apply stem-cells treatments for neurodegenerative diseases and conditions such as diabetes, heart disease, and other conditions.Cord blood stem cells therapy is highly recommended at the time of delivery to save the umbilical cord of the child to resolve any future health conditions. Umbilical cord stem cells research has more scope to resolve the issues caused due to DNA changes.
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Track-4
Epigenetics
Epigeneticsis the study of potentially heritable changes in gene expression (active versus inactive genes) that does not involve changes to the underlyingDNA sequence a change in phenotype without a change in genotype which in turn affects how cells read the genes. Epigenetic change is a regular and natural occurrence but can also be influenced by several factors including age, the environment/lifestyle, and disease state. Epigenetic modifications can manifest as commonly as the manner in which cells terminally differentiate to end up as skin cells, liver cells, brain cells, etc. Or, epigenetic change can have more damaging effects that can result in diseases like cancer. At least three systems includingDNA methylation, histone modification and non-coding RNA (ncRNA)-associated gene silencing are currently considered to initiate and sustain epigenetic change. New and ongoing research is continuously uncovering the role of epigenetics in a variety ofhuman disordersand fatal diseases.
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Track-5
Stem cells apoptosis and signal transduction
Self-renewal and proliferation ofstem cellspopulation is controlled, in part, by induction of apoptosis. The number of stem cells is therefore a balance between those lost to differentiation / apoptosis and those gained through proliferation.Apoptosisof stem cells is believed to be a dynamic process which changes in response to environmental conditions. For example, the release of stem cells factor inhibits apoptosis following spinal cord injury, presumably in an attempt to promotetissue repair. Dysregulation of apoptosis instem cellsis believed to underlie somecancer pathologies, where apoptotic resistance results in uncontrolled growth (i.e. glioblastoma). Controlling apoptosis is also an important focus for studies ofstem cells transplantation, where inhibition may increase the survival of grafted cells during replacement therapy. Harnessing the full therapeutic potential of stem cells will require full elucidation of the signal transduction cascades for proliferation, differentiation, and apoptosis.
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Trcak-6
Regenerative medicine
Regenerative medicineis the branch of medicine that develops methods to regrow, repair or replace damaged or diseased cells, organs or tissues. Regenerative medicine includes the generation and use of therapeutic stem cells, tissue engineering and the production of artificial organs.
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Track-7
Bio-banks
Biobanksplay a crucial role in biomedical research. The wide array ofbio specimens(including blood, saliva, plasma, and purified DNA) maintained inbiobankscan be described as libraries of the human organism. They are carefully characterized to determine the general and unique features of the continuous cell line and the absence or presence of contaminants, therefore establishing a fundamental understanding about the raw material from which the biological product is being derived and maintained.Biobankscatalog specimens using genetic and other traits, such as age, gender, blood type, and ethnicity. Some samples are also categorized according to environmental factors, such as whether the donor had been exposed to radiation, asbestos, or some other substance that can affecthuman genes.In Biobank Category the most popular biobank projects includes cord blood banking, banking stem cells, baby cord blood banking.
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Track-8
Stem cells biomarkers
Bio markeris a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A bio marker may be used to see how well the body responds to a treatment for a disease or condition.
In cancer research and medicine, bio markers are used in three primary ways:
To help diagnose conditions, as in the case of identifying early stage cancers (Diagnostic)
To forecast how aggressive a condition is, as in the case of determining a patient's ability to fare in the absence of treatment (Prognostic)
To predict how well a patient will respond to treatment (Predictive).
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Track-9
Cells & Organ Regeneration
Regenerationmeans the regrowth of a damaged or missing organ part from the remaining tissue. As adults, humans can regenerate some organs, such as the liver. If part of the liver is lost by disease or injury, the liver grows back to its original size, though not its original shape. And our skin is constantly being renewed and repaired. Unfortunately many other human tissues dont regenerate, and a goal inregenerative medicineis to find ways to kick-start tissue regeneration in the body, or to engineerreplacement tissues.
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Track-10
Fertility biobanks
Fertility preservation is the effort to help cancer patients retain their fertility, or ability to procreate. Research into howcanceraffects reproductive health and preservation options are growing, sparked in part by the increase in the survival rate of cancer patients. The main methods of fertility preservation are ovarian protection by GnRH agonists, cryopreservation of ovarian tissue, eggs or sperm, or of embryos afterin vitro fertilization. The patient may also choose to use egg or sperm from a donor by third party reproduction rather than having biological children.
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Track-11
Biobank Ethics
Ethical issues are commonly present in many aspects ofBiobanking. The fact that Biobanks deal with human samples, invading an individual autonomy or limiting self-control, provokes a number of ethical issues. Who is actually competent to give informed consent and donate a sample? When individuals donate part of their body to abiobank, how is that human sample processed? Who is the owner of the sample? Who should decide how it should be used? Who has the right to know individual results of research? These and many more ethical dilemmas exist in the ethical framework of biobanks. With the recent rapid developments in Biobanking, all of these issues are magnified with plenty of further new questions continuously arising. Ethical framework has been the most controversial issue in the domain of biobanking. Thus, it is not surprising that there is a substantial literature focusing on ethical dilemmas in biobanking, such as informed consent, privacy, protection, and returning of results to participants. For many years, researchers at CRB have provided constructive advice on how to deal with ethical aspects of research usinghuman tissuematerial and personal data. For more than 80 years tissue has been derived from human bodies, stored, distributed and used for therapeutic, educational, forensic and research purposes as part of healthcare routine in most western countries.
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Track-12
Market Analysis in Biobanking
The globalbiopreservationmarket is expected to reach USD 3,731.03 Million by 2020 from USD 2,150.48 Million in 2015, growing at a CAGR of 11.65% between 2015 and 2020. Biopreservation is used to ensure the stability, quality and purity ofbiospecimens. With a CAGR of 23.7%, global market value for cryopreservation equipment used instem cellsindustry is anticipated to worth US$2.2 billion by 2015. On a global scale, North America accounts for nearly 35% of the market and will likely witness a higher growth rate in the upcoming years, in comparison with Asia-Pacific. While US accounts for the highest share of the global market value on a country basis, India and China surpasses the US in terms of growth rate anticipated in the near future. As per our analysis, freezers represent more than half of thecryopreservationequipment market value while Cyropreservative reagents stand for a share of close to 20%. The global biopreservation market is poised for rapid growth between 2015 and 2020. The drivers include increasing healthcare expenditure, growing demand for preserving new-borns stem cells, increasing R&D spending on research, and increasing adoption ofregenerative medicine.
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Track-13
Next Generation Biobanking
Biorepositoriesprovide a resource for researchers to increase understanding of complex diseases. Studies such as the Lung Genomics Research Consortium (LGRC), a two-year project launched in October 2009, are going a step further than standardbiobanking practicesand characterizing the samples with their molecular makeup. The molecular data can then be mined along with the clinical data. Led by National Jewish Health and funded by the National Heart, Lung and Blood Institute, a division of the National Institutes of Health (NIH), the LGRC project consists of five institutions, including Dana-Farber Cancer Institute. Collaborators in the project work with samples banked at theLung Tissue ResearchConsortium (LTRC), which houses tissue samples and blood from lung disease sufferers, primarily chronic obstructive pulmonary disease (COPD), along with a rich set of clinical data from patients.
Immuno-Oncology London UK, Next-Generation Cancer Immunotherapies San Diego, USA, ESBB conference Johannesburg, South Africa, HandsOn Biobanks 2016 conference Vienna, Austria, American Society forBioethicsand Humanities Houston, USA, Craniofacial Morphogenesis &Tissue RegenerationVentura, CA, USA, ISSCR Pluripotency: From basic science to therapeutic applications Kyoto, Japan, Craniofacial Morphogenesis & Tissue Regeneration Ventura, CA, USA, Phacilitate Cell &Gene TherapyWorld Washington D.C., USA, Notch Signaling in Development, Regeneration & Disease Gordon Research Conference Lewiston, ME, USA.
The biobanking market is poised for explosive growth if it can overcome the challenges of an adolescent industry. According to an August 2012 Infiniti Research report titled Global Biobanking Market 2011-2015, the biobanking market will increase 30 per cent from 2011 to 2015 to nearly $183 billion. Growth is being driven by an increase in populationgeneticsstudies, personalized medicine, and the use of genetic information in food safety, forensics, and disease surveillance.
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