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Scientists identify 2nd HIV patient whose body rid itself of virus – National Herald

November 21st, 2021 1:47 am

In most people, new viral particles are constantly made from this reservoir. Anti-retroviral therapy (ART) can prevent the new viruses from being made but cannot eliminate the reservoir, necessitating daily treatment to suppress the virus.

Some people, known as elite controllers, have immune systems that are able to suppress HIV without the need for medication. Though they still have viral reservoirs that can produce more HIV virus, a type of immune cell called a killer T-cell keeps the virus suppressed without the need for medication.

Yu explained that the new findings may suggest a specific killer T-cell response common to both patients driving this response, with the possibility that other people with HIV have also achieved a sterilising cure.

If the immune mechanisms underlying this response can be understood by researchers, they may be able to develop treatments that teach others' immune systems to mimic these responses in cases of HIV infection.

"We are now looking toward the possibility of inducing this kind of immunity in persons on ART through vaccination, with the goal of educating their immune systems to be able to control the virus without ART," Yu said.

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Scientists identify 2nd HIV patient whose body rid itself of virus - National Herald

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