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Rheum Round-up: Rheumatic Disease and COVID-19 Severity, Improving Hip Fracture Outcomes, and more – DocWire News

August 17th, 2020 1:52 pm

Here are the top stories recently covered by DocWire News in the rheumatology section. In this edition, read about the effect of rheumatic diseases on COVID-19 severity, virtual computer-assisted preoperative planning in hip fracture, racial disparities in psoriatic arthritis, and fatigue in rheumatic diseases.

Hospitalized COVID-19 patients with connective tissue diseases may be at risk for increased illness severity, according to a recent study, but inflammatory arthritis (IA) may not have the same effect. Final analysis included 456 patients each in rheumatic and non-rheumatic groups. In the rheumatic disease cohort, 60% of patients had IA, and 40% had connective tissue disease. About three-quarters of patients (74%) were hospitalized. The risk of severe COVID-19 was 31.6% in the rheumatic cohort and 28.1% in the non-rheumatic cohort. In bivariate analysis, factors associated with increased COVID-19 severity risk in the rheumatic group were aging; male sex; and previous comorbidity including obesity, diabetes, hypertension, or cardiovascular or lung disease. Upon logistic regression analysis, the factors independently associated with severe COVID-19 disease were increased age, male sex, and connective tissue disease.

An estimated 300,000 hip fractures occur in the U.S. each yeara number that is expected to double with the aging population. About half of hip fractures are intertrochanteric fractures, but postoperative outcomes tend to be poor, including a high risk of mortality as well as poorer functional and quality of life outcomes. Certain risk factors for such poor outcomes are age and sexwhich cannot be modified. One thing that can be modified, though, is preoperative planning. And according to a study, computer-assisted virtual planning in cases of intertrochanteric hip fracture may improve postoperative complications, including mortality risk.

A study observed how ethnicity may affect disease expression of psoriatic arthritis (PsA), observing differences between patients of South Asian (SA) versus North European (NE) descent. They concluded that SA patients may have poorer clinical outcomes and be more adversely affected by PsA disease than NE patients.

IA patients often experience fatigue; 41% to 51% of rheumatoid arthritis, PsA, and spondyloarthritis patients suffer from severe fatigue. Patients with these rheumatic diseases who are plagued by fatigue may suffer in several domains, including quality of life, work impairment, depression, and more, according to a new study.

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Rheum Round-up: Rheumatic Disease and COVID-19 Severity, Improving Hip Fracture Outcomes, and more - DocWire News

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