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Preventive Medicine – Atlanta, GA – yelp.com

October 4th, 2019 9:46 am

Specialties

Since 1996 our team of dedicated doctors and nurse practitioners have been committed to providing preventive medicine for men and women suffering from health concerns such as hypertension, heavy metal toxicity, and hormone deficiency. Our anti-aging clinic outranks others of its kind, thanks to our remarkably cutting edge and talented group of doctors.

Robert A. Burkich, MD is the founder and medical director at the facility and has nearly 20 years of experience with private practice medicine. Dr. Burkich specializes in anti-aging and believes in treating his patients from the inside out. His approach is methodical and successful, time and time again. It starts with reducing heavy metals and other toxins from the body to improve blood flow. How does this help? By removing toxins, improving blood flow and hormone levels, it allows you to maintain an ideal body weight, keep energy levels up, diminish fatigue and mental fogginess, improve sexual function, and improve outward appearance

Established in 2010.

Since 1996 our team of dedicated doctors and nurse practitioners have been committed to providing preventive medicine for men and women suffering from health concerns such as hypertension, heavy metal toxicity, and hormone deficiency. Our anti-aging clinic outranks others of its kind, thanks to our remarkably cutting edge and talented group of doctors.

Robert A. Burkich, MD is the founder and medical director at the facility and has nearly 20 years of experience with private practice medicine. Dr. Burkich specializes in anti-aging and believes in treating his patients from the inside out. His approach is methodical and successful, time and time again. It starts with reducing heavy metals and other toxins from the body to improve blood flow. How does this help? By removing toxins, improving blood flow and hormone levels, it allows you to maintain an ideal body weight, keep energy levels up, diminish fatigue and mental fogginess, improve sexual function, and improve outward appearance.

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Preventive Medicine | Family Medicine | Michigan Medicine …

October 4th, 2019 9:46 am

Michael D. Fetters, M.D., M.P.H., M.A., U-M Site Principal Investigator

Funded by the National Institutes of Health,National Institute Of Diabetes And Digestive And Kidney Diseases toVirginia Commonwealth University ($485,649)

Study Dates: June 2018 - June 2021

The overall goal of this research is to identify physicians communication behaviors during medical interactions that are associated with physicians implicit racial bias and Black patients immediate (satisfaction, trust) as well as clinically important longer-term outcomes (adherence, healthcare utilization).

To achieve this goal, we target medical interactions involving Black patients with Type 2 diabetes mellitus (T2DM) because nonadherence in Black patients with T2DM is particularly prevalent. Additionally, the patient-physician communication quality has been found to predict patient adherence to T2DM treatment regimens. We will use a mixed-methods design that integrates the strengths of inductive reasoning to explore which physicians communication behaviors during medical interactions matter from Black patients perspectives and deductive reasoning to identify theoretically and clinically important behaviors.

Our aims are:

Study Protocol Citation:Hagiwara N, Mezuk B, Lafata JE, Vrana SR,Fetters MD. Study protocol for investigating physician communication behaviours that link physician implicit racial bias and patient outcomes in Black patients with type 2 diabetes using an exploratory sequential mixed methods design. BMJ Open. 2018;8(10). doi:10.1136/bmjopen-2018-022623.

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Preventive Care | UnitedHealthcare

October 4th, 2019 9:46 am

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Routine preventive care helps you manage and maintain your health, and is generally covered at 100% by most health plans.

Schedule an appointment today or set a calendar reminder.

* indicates a required field

Understand the difference between preventive care and diagnostic care.

Preventive care is designed to help you stay healthy, and is covered by most health plans with $0 out-of-pocket when you see a network provider.

Costs may be incurred for diagnostic care based on plan coverage.

Preventive care includes routine well exams, screenings, and immunizations intended to prevent or avoid illness or other health problems.

Diagnostic care includes care or treatment when you have symptoms or risk factors and your doctor wants to diagnose them.

Set a reminder to schedule an appointment.

Find a provider, get plan coverage details and more.

Find network flu shot locations and track flu outbreaks.

Downloadable resources:

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Mayo Clinic Transplant Center – Regenerative medicine …

October 3rd, 2019 2:50 pm

Mayo Clinic Regenerative Medicine Consult Service

At Mayo Clinic, an integrated team, including stem cell biologists, bioengineers, doctors and scientists, work together and study regenerative medicine. The goal of the team is to treat diseases using novel therapies, such as stem cell therapy and bioengineering. Doctors in transplant medicine and transplant surgery have pioneered the study of regenerative medicine during the past five decades, and doctors continue to study new innovations in transplant medicine and surgery.

In stem cell therapy, or regenerative medicine, researchers study how stem cells may be used to replace, repair, reprogram or renew your diseased cells. Stem cells are able to grow and develop into many different types of cells in your body. Stem cell therapy may use adult cells that have been genetically reprogrammed in the laboratory (induced pluripotent stem cells), your own adult stem cells that have been reprogrammed or cells developed from an embryo (embryonic stem cells).

Researchers also study and test how reprogrammed stem cells may be turned into specialized cells that can repair or regenerate cells in your heart, blood, nerves and other parts of your body. These stem cells have the potential to treat many conditions. Stem cells also may be studied to understand how other conditions occur, to develop and test new medications, and for other research.

Researchers across Mayo Clinic, with coordination through the Center for Regenerative Medicine, are discovering, translating and applying stem cell therapy as a potential treatment for cardiovascular diseases, diabetes, degenerative joint conditions, brain and nervous system (neurological) conditions, such as Parkinson's disease, and many other conditions. For example, researchers are studying the possibility of using stem cell therapy to repair or regenerate injured heart tissue to treat many types of cardiovascular diseases, from adult acquired disorders to congenital diseases. Read about regenerative medicine research for hypoplastic left heart syndrome.

Cardiovascular diseases, neurological conditions and diabetes have been extensively studied in stem cell therapy research. They've been studied because the stem cells affected in these conditions have been the same cell types that have been generated in the laboratory from various types of stem cells. Thus, translating stem cell therapy to a potential treatment for people with these conditions may be a realistic goal for the future of transplant medicine and surgery.

Researchers conduct ongoing studies in stem cell therapy. However, research and development of stem cell therapy is unpredictable and depends on many factors, including regulatory guidelines, funding sources and recent successes in stem cell therapy. Mayo Clinic researchers aim to expand research and development of stem cell therapy in the future, while keeping the safety of patients as their primary concern.

Mayo Clinic offers stem cell transplant (bone marrow transplant) for people who've had leukemia, lymphoma or other conditions that have been treated with chemotherapy.

Mayo Clinic currently offers a specialty consult service for regenerative medicine within the Transplant Center, the first consult service established in the United States to provide guidance for patients and families regarding stem cell-based protocols. This consult service provides education and consultation for people with many conditions who have questions about the potential use of stem cell therapy. The staff provides guidance to determine whether stem cell clinical trials are appropriate for these individuals. Regenerative medicine staff may be consulted if a doctor or patient has asked about the potential use of stem cell therapies for many conditions, including degenerative or congenital diseases of the heart, liver, pancreas or lungs.

People sometimes have misconceptions about the use and applications of stem cell therapies. This consult service provides people with educational guidance and appropriate referrals to research studies and clinical trials in stem cell therapies for the heart, liver, pancreas and other organs. Also, the consult service supports ongoing regenerative medicine research activities within Mayo Clinic, from basic science to clinical protocols.

Read more about stem cells.

For more information about Mayo Clinic's regenerative medicine consultation service, please call 844-276-2003 (toll free) Monday through Friday from 8 a.m. to 5 p.m. Central time.

Share your Mayo Clinic transplant experience with others using social media.

Oct. 02, 2019

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Regenerative Medicine – an overview | ScienceDirect Topics

October 3rd, 2019 2:50 pm

1 Introduction

Regenerative medicine is characterized as the process of replenishing or restoring human cells, tissues, or organs to restore or reestablish normal function. This field holds the promise of transforming human medicine, by actually curing or treating diseases once poorly managed with conventional drugs and medical procedures.

It informally started almost 60years ago with the first successful organ transplant performed in Boston by a team led by Dr Joseph Murray, John Merrill, and J. Hartwell Harrison.1 This landmark accomplishment marked a new era in the emerging field of organ transplantation and allowed for the first time for the complete cure of a patient with end-stage organ disease.

The first effective cell therapies with bone marrow transplants followed in the late 1950s and 1960s. A team led by Dr Don Thomas was the first to treat leukemic patients with allogeneic marrow transplants in Seattle.2,3 This was later followed by Dr Robert Good in 1968, where an immunodeficient patient was successfully treated with an allogeneic bone marrow transplant from his sibling at the University of Minnesota.4

Throughout these decades, many attempts on organ transplantation, cell therapies, and gene therapy ended in failure, but this vigorous scientific and clinical interest established the basis of the first wave of successes that regenerative medicine experienced and delivered to the clinic.58

With this paradigm change in medicine, came the first challenges of organ shortage and higher demand for matching bone marrow donors. Organ shortages established a driving force for novel advancements in molecular and cell biology that opened new avenues in several areas in regenerative medicine. The fields of cell transplantation and tissue engineering were proposed as alternatives to tissue and organ shortage by de novo reconstitution of functional tissues and organs in the laboratory for transplantation, and the use of cells for therapy.

The present book you have just started to explore is an introduction for the translational and basic researcher as well as the clinician to the vast field of regenerative medicine technologies. It is the second book in a new series, Advances in Translational Medicine and presents 23 key chapters that describe in detail some of the contemporary regenerative medicine advances in different medical fields. These chapters review the state-of-the-art experimental data available from the bench, along with vital information provided by multiple clinical trials, giving a broad view of current and near future strategies to treat or cure human disease.

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Regenerative Medicine | Stem Cell Treatments | PRP | Houston …

October 3rd, 2019 2:50 pm

What is regenerative medicine? This fast growing, highly effective treatment option utilizes various treatments that may include stem cells and growth factors including, umbilical allografts, amniotic fluid, mesenchymal stem cells and platelet rich plasma or PRP treatments to heal and restore your body to a healthy level. The very name indicates that regenerative medicine therapies help your body regenerate tissue, bone, discs, cartilage, and cells. This treatment option provides relief from injuries and chronic pain. Regenerative medicine is a natural solution that even helps combat the effects of aging.

Our team of doctors will design a customized treatment program just for you. A custom program is far more effective than a "one size fits all" treatment option. Our solutions are designed to help your body truly heal rather than simply mask your symptoms.

Stem cell therapy is not regenerative medicine. Regenerative medicine helps your body restore itself to a healthy state naturally. Patients in pain, those with wounds that wont heal or with damaged cartilage, muscle or ligaments may return to normal life in a short time. Regenerative cell therapy may also help arthritic patients find relief from the swelling, pain and lack of mobility resulting from this condition. It will even help those that have had recent surgery heal more quickly and reduce scar tissue.

There are many sources for stem cells. However, we fell that the mesenchymal stem cells obtained from umbilical cords offer the most potent and effective healing power. Why are young stem cells more favorable than those in our bodies naturally? Our body's own stem cells age as we age and are therefore less effective year after year. The stem cells harvested from the umbilical cord the day of birth show an extremely high rate of replication. To illustrate this, simply think about how much more quickly children heal from injuries than do elder people. This is due to their young, healthy stem cells.

When introduced into an injured or damaged area, stem cells go to work to accelerate and enhance your natural healing process. They are reported to help your body heal muscle tears, ligament or tendon damage, strengthen degenerating bones and cartilage and more. Stem cells are undifferentiated cells meaning that they transform into the exact cells your body needs to heal itself. They even have the ability to help with the inflammation and pain that accompanies arthritis and other conditions.

The most active healing cells contained in your blood are called platelets. When your body signals that it is injured, platelets are attracted to the injured area. They then go to work repairing that area. To focus this healing power intensively on your injury, we extract a small quantity of your blood. The next step is to process it and isolate the platelets in clear plasma. This platelet-rich plasma will then be returned to your injured area. PRP treatments of knees, shoulders, muscles, tendons and other parts of the body have proven remarkably effective.

Most often the fastest relief after a regenerative medicine treatment comes from the anti inflammatory properties of the injection. The longer term results are the result of your body healing itself and restoring the damaged tissue. These procedures regenerate cells, tissue, bone, ligaments, tendons muscles, cartilage, and more. Stem cell treatments are found to help those with heart conditions, alopecia, peripheral neuropathy, skin rejuvenation, hair restoration, etc. Choosing regenerative medical treatment options and regenerative cell therapy helps your body tap into its youthful healing potential. You can expect hair restoration, younger looking skin and improved quality of life.

O-Shots: This life changing, revolutionary use of regenerative medicine utilizes platelet-rich plasma to improve vaginal tone and sexual response. By injecting PRP into anesthetized genital areas, regeneration of tissue in the area is triggered. These PRP injections increase blood flow to these sensitive and responsive tissues. Improved sensation during sexual activity is the result, along with a reduction of urinary incontinence and other symptoms.

P-Shots: The P-shot, or Priapus Shot, offers similar benefits for men. In this case, the patients own platelets are injected into numbed areas of the penis. Growth factors that are abundant in platelet-rich plasma rejuvenate the tissues in the penis involved in creating erections and responding to stimuli. Resulting in more satisfying sexual experiences.

Medical science has moved beyond simply covering up a patients problems with steroids, painkillers and muscle-relaxing drugs and has embraced regenerative medicine and regenerative cell therapy as better solutions to heal pain and injuries. At Campbell Medical Group, we offer cutting-edge regenerative medicine and stem cell treatments that rebuild, regenerate and restore so we can return you to the pain-free and active life you enjoy leading.

Call our office for a free consultation on our cutting edge regenerative medicine in Houston

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Regenerative Medicine | Stem Cell Treatments | PRP | Houston ...

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Tissue Science Conferences| Regenerative Medicine Conferences …

October 3rd, 2019 2:50 pm

Sessions & Tracks

Scaffolds

Scaffoldsare one of the three most important essentials constituting the basic concept ofRegenerative Medicine, and are included in the core technology of Regenerative Medicine. Every day thousands of surgical procedures are done to replace or repair tissue that has been damaged through disease or trauma. The developing field oftissue engineering(TE) aims to regenerate damagedtissuesby combining cells from the body with highly porous scaffoldbiomaterials, which act as templates fortissue regeneration, to guide the growth of new tissue. Scaffolds has a prominent role in tissue regeneration the designs, fabrication, 3D models, surface ligands andmolecular architecture, nanoparticle-cell interactions and porous of the scaffolds are been used in the field in attempts to regenerate different tissues and organs in the body. The worldstem cell marketwas approximately 2.715 billion dollars in 2010, and with a growth rate of 16.8% annually, a market of 6.877 billion dollars will be formed in 2016. From 2017, the expected annual growth rate is 10.6%, which would expand the market to 11.38 billion dollars by 2021.

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Cord Blood Stem Cells and Regenerative Medicine

Recently,cord blood stems cellsare developed in the treatment of different diseases, including a broad range of cancers,blood disorders, and genetic diseases. In a cordblood transplant, stem cells are infused in to a patients bloodstream for healing and repairing damaged cells and tissue. In a successful transplant, new healthy immune system has been created. The natural power and purity of newborn's cord blood are responsible for healthy development during gestation.Cord bloodapplications have developed beyondtransplant medicineinto the areas ofregenerative medicineincluding brain injuries, autism,Cardiac Problems, andAutoimmune Deficiencies. The latest research in routine transplantation of cord blood are reviewed followed by the critical role ofcord bloodstem cells in regenerative medicine research and novel approaches using cord blood as a source of whole blood for transfusion.

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);British Association of Tissue Banks;British Association for Tissue Banking;European Tissue Repair Society;Spanish Association of Tissue Bank;European Calcified Tissue Society;European Association of Tissue Banks;

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR).

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS).

Bone and Cartilage Tissue Engineering

This interdisciplinary engineering has attracted much attention as a new therapeutic means that may overcome the drawbacks involved in the current artificial organs and organ transplantation that have been also aiming at replacing lost or severelydamaged tissuesor organs.Tissue engineeringandregenerative medicineis an exciting research area that aims at regenerative alternatives to harvested tissues for organ transplantation withsoft tissues. Although significant progress has been made in thetissue engineeringfield, many challenges remain and further development in this area will require on-going interactions and collaborations among the scientists from multiple disciplines, and in partnership with the regulatory and the funding agencies. As a result of the medical and market potential, there is significant academic and corporate interest in this technology.

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);ScanBalt Stem Cell Research Network;

USA:California Institute for Regenerative Medicine (CIRM);American Association of tissue banks;New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);

Asia:Asia Pacific Association of Surgical Tissue Banking;The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;

Stem cells to Battle cancer

Stem cell transplant is treatment in some types of cancers like leukemia, multiple myeloma, or some types of lymphoma. Stem cell transplantation is the procedure that restores blood-forming stem cells in patients who have had theirs destroyed by the very high doses of chemotherapy or radiation therapy that are used to treat certain cancers.

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Novel Approaches guided in Tissue Engineering

GTR are dental surgical procedures that use barrier membranes to direct the growth of new bone and gingival tissue at sites with insufficient volumes or dimensions of bone or gingiva for proper function, esthetics or prosthetic restoration

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Clinical Medicine

Clinical medicine relates to medicine field that deals mainly with the study and practice of medicine based on the direct examination of the patient. In clinical medicine, medical practitioners assess patients in order to diagnose, treat, and prevent disease

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Clinical trials with Stem Cells

Stem cell treatments and clinical trials have been going on for over 40 years; however we are still in the initial stages of stem cell therapy being utilized as an effective alternative treatment method to traditional pharmaceutical based treatments. Much of the early work in stem cell clinical trials focused on the overall effectiveness and safety of the procedures involved. The primary concern with any new treatment is the long term safety and standardization of results. There have been countless journals and research papers focusing in on these clinical trials that have revealed promising results from these initial trials around the world

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Biomaterials & Bioengineering

Biomaterials are being utilized for the social insurance applications from old circumstances. In any case, consequent development has made them more flexible and has expanded their utility. Biomaterials have reformed the territories like bioengineering and tissue designing for the advancement of novel methodologies to battle perilous infections. Together with biomaterials, immature microorganism innovation is additionally being utilized to enhance the current human services offices. These ideas and innovations are being utilized for the treatment of various maladies like cardiovascular disappointment, cracks, profound skin wounds, and so forth. Presentation of nanomaterials then again is turning into a major seek after a superior and a reasonable social insurance. Mechanical headways are in progress for the advancement of persistent observing and controlling glucose levels by the implantation of sensor chips.

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Biomarkers

Biomarkers, in the hands of clinical investigators, provide a dynamic and powerful approach to understanding the spectrum of diseases with obvious applications in analytic epidemiology, biomarkers and clinical research in disease prevention, diagnosis and disease management. Biomarkers have the additional potential to identify individuals susceptible to particular diseases. This conference is a podium that brings and shares collective knowledge and research explorations in biomarkers study. In the recent years, the information about cancer biomarkers has increased largely providing a huge potential for improving the management of cancer patients by improving the accuracy of detection and efficacy of treatment. Latest technological advancements have enabled the examination of many possible biomarkers and renewed interest in developing new biomarkers. All such developments can be evidenced in this biomarker congress.

Cancer Biomarkers, Molecular Biomarkers, Genomics biomarkers, Biomarkers in Clinical Research & Development, Biomarkers and Pathology

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Regeneration & Therapeutics

Some parts of our bodies can repair themselves quite well after injury, but others dont repair at all. We certainly cant regrow a whole leg or arm, but some animals can regrow - or regenerate - whole body parts. Regeneration means the regrowth of a damaged or missing organ part from the remaining tissue. As adults, humans can regenerate some organs, such as the liver. If part of the liver is lost by disease or injury, the liver grows back to its original size, though not its original shape. And our skin is constantly being renewed and repaired. Unfortunately many other human tissues dont regenerate, and a goal in regenerative medicine is to find ways to kick-start tissue regeneration in the body, or to engineer replacement tissues.

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

The New South Wales Stem Cell Network;Korean Society for Stem Cell Research;Japanese Society for Regenerative Medicine;Taiwan Society for Stem Cell Research;Stem Cell Society Singapore (SCSS);

Rejuvenation

Rejuvenation is a medical discipline focused on the practical reversal of the aging process. Rejuvenation is distinct from life extension. Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. Rejuvenation is the reversal of aging and thus requires a different strategy, namely repair of the damage that is associated with aging or replacement of damaged tissue with new tissue. Rejuvenation can be a means of life extension, but most life extension strategies do not involve rejuvenation.

Immunotherapy

Immunotherapy, also called biologic treatment, is a kind of disease treatment that lifts the body's common guards to battle the malignancy. It utilizes substances made by the body or in a research facility to enhance or re-establish safe framework work. Immunotherapy may work in these ways: Halting or abating the development of tumor cells, preventing malignancy from spreading to different parts of the body, helping the safe framework work better at crushing disease cells. There are several types of immunotherapy, including: Monoclonal antibodies, Non-specific immunotherapies, oncolytic virus therapy, T-cell therapy, Cancer vaccines

RelatedRegenerative Medicine Conferences|Stem Cell Conferences|Stem Cell Congress|Tissue Science Conferences|EuropeConferences

9th Advanced Cell and Gene Therapy conference, March 21-22, 2019 Rome, Italy; 12th Genomics and Molecular Biology conference, April 15-17, 2019 Berlin, Germany; 7th Integrative Biology conference, April 15-16, 2019 Berlin, Germany; Pacific Regenerative Medicine Conference, May 16-19, 2019 Hawaii, USA; Annual conference & Exhibition on Transversal, Translational & Transformative, December 2-5, 2019 Florida, USA; 21st International Conference on Tissue Engineering and Regenerative Medicine, June 27 - 28, 2019 London, United Kingdom; World Advanced Therapies & Regenerative Medicine Congress 2019, May 15 17, London, UK; 6th Annual European Congress on Clinical & Translational Sciences, October 18-20, 2019 Vienna, Austria;

Related Associations and Societies:

Europe:EuroStemCell (European Consortium for Stem Cell Research);German Stem Cell Network (GSCN);German Society for Stem Cell Research (GSZ);Stem Cell Network North Rhine-Westphalia (NRW);Norwegian Center for Stem Cell Research (NCSCR);

USA:California Institute for Regenerative Medicine (CIRM);New York Stem Cell Foundation (NYSCF);Tissue Engineering International & Regenerative Medicine Society (TERMIS);International Society for Stem Cell Research (ISSCR);

Asia:

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10 Causes of Neuropathy – Facty Health

October 3rd, 2019 2:49 pm

Neuropathy occurs in the feet or hands due to nerve damage. When a patient suffers from neuropathy, they can experience so-called neuropathic pain ranging from mild to severe and described as burning, pinpricks, or sudden shocks of electricity, as well as numbness, tingling, and weakness. The peripheral nervous system utilizes nerves to send messages to and from the central nervous system, which includes both the brain and spinal cord. When these peripheral nerves become damaged and their ability to transmit signals, neuropathy results. Although neuropathy is an encompassing diagnosis, there are many causes.

Diabetes can cause chronic neuropathy. High blood sugar levels can damage nerves, predominantly in the feet. This is why neuropathy more often occurs in people whose blood sugar is not under control than those who maintain low blood sugar levels. Diabetic neuropathy as a result of uncontrolled blood glucose levels can create irreversible damage to the nerves. When diabetes is under control, the amount of sugar in the blood remains at a safe level, thus reducing the risk of potential nerve damage.

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The Best Treatment for Peripheral Neuropathy in Feet …

October 3rd, 2019 2:49 pm

Peripheral neuropathy is a condition that can affect the feet with a sensation of burning, tingling or numbness that may be periodic or constant. It is a frequent symptom of nerve trauma or pressure, vitamin B deficiency, alcoholism, diabetes, autoimmune diseases (such as HIV, lupus or rheumatoid arthritis) and diseases of the liver, kidneys and thyroid. Because peripheral neuropathy is involved in so many conditions, treatments vary widely.

Most drugs prescribed specifically for peripheral neuropathy will block or decrease the nerve sensations. They may include codeine, lidocaine, anti-seizure medications and antidepressants. Because some of these can cause dependency over long periods of time, other solutions may be tried first. Rubbing cremes on the feet or immersing them in warm water periodically may be an alternative.

The best treatment for peripheral neuropathy in the feet is to eliminate the cause. If the cause is clear -- abstain from alcohol, supplement vitamin B, brace joints to relieve pressure and so on -- those treatments should relieve the neuropathy. Many causes, however, are chronic and are not easily eliminated.

For those with chronic conditions causing their neuropathy, seeking treatment with a hypnotist trained in medical hypnosis may lead to more complete and convenient pain control than with oral pain relievers. Regular acupuncture treatments, perhaps with moxibustion, may also lead to a decreased pain sensation. In addition, t'ai chi ch'uan (taijiquan) may increase sensory perception for those with numbness in the feet.

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Peripheral Neuropathy Symptoms | Pain In Fingers, Toes, & Feet.

October 3rd, 2019 2:49 pm

Peripheral Neuropathy symptoms usually start with numbness, prickling or tingling in the toes or fingers. It may spread up to the feet or hands and cause burning, freezing, throbbing and/or shooting pain that is often worse at night.

The pain can be either constant or periodic, but usually the pain is felt equally on both sides of the bodyin both hands or in both feet. Some types of peripheral neuropathy develop suddenly, while others progress more slowly over many years.

Symptoms such as experiencing weakness or not being able to hold something, not knowing where your feet are, and experiencing pain that feels as if it is stabbing or burning in your limbs, can be common signs and symptoms of peripheral neuropathy.

The symptoms of peripheral neuropathy may depend on the kind of peripheral nerves that have been damaged.There are three types of peripheral nerves: motor, sensory and autonomic. Some neuropathies affect all three types of nerves, while others involve only one or two.

The majority of people, however, suffer from polyneuropathy, an umbrella term for damage involving many nerves at the same time.

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Peripheral Neuropathy | Johns Hopkins Medicine

October 3rd, 2019 2:49 pm

Peripheral Neuropathy

Peripheral neuropathy is a type of damage to the nervous system. Specifically, it is a problem with your peripheral nervous system. This is the network of nerves that sends information from your brain and spinal cord (central nervous system) to the rest of your body.

Peripheral neuropathy has many different causes. Some people inherit the disorder from their parents. Others develop it because of an injury or another disorder.

In many cases, a different type of problem, such as a kidney condition or a hormone imbalance, leads to peripheral neuropathy. One of the most common causes of peripheral neuropathy in the U.S. is diabetes.

There are more than 100 types of peripheral neuropathy, each with its own set of symptoms and prognosis. To help doctors classify them, they are often broken down into the following categories:

Motor neuropathy. This is damage to the nerves that control muscles and movement in the body, such as moving your hands and arms or talking.

Sensory neuropathy. Sensory nerves control what you feel, such as pain, temperature or a light touch. Sensory neuropathy affects these groups of nerves.

Autonomic nerve neuropathy. Autonomic nerves control functions that you are not conscious of, such as breathing and heartbeat. Damage to these nerves can be serious.

Combination neuropathies. You may have a mix of 2 or 3 of these other types of neuropathies, such as a sensory-motor neuropathy.

The symptoms of peripheral neuropathy vary based on the type that you have and what part of the body is affected. Symptoms can range from tingling or numbness in a certain body part to more serious effects such as burning pain or paralysis.

Muscle weakness

Cramps

Muscle twitching

Loss of muscle and bone

Changes in skin, hair, or nails

Numbness

Loss of sensation or feeling in body parts

Loss of balance or other functions as a side effect of the loss of feeling in the legs, arms, or other body parts

Emotional disturbances

Sleep disruptions

Loss of pain or sensation that can put you at risk, such as not feeling an impending heart attack or limb pain

Inability to sweat properly, leading to heat intolerance

Loss of bladder control, leading to infection or incontinence

Dizziness, lightheadedness, or fainting because of a loss of control over blood pressure

Diarrhea, constipation, or incontinence related to nerve damage in the intestines or digestive tract

Trouble eating or swallowing

Life-threatening symptoms, such as difficulty breathing or irregular heartbeat

The symptoms of peripheral neuropathy may look like other conditions or medical problems. Always see your healthcare provider for a diagnosis.

The symptoms and body parts affected by peripheral neuropathy are so varied that it may be hard to make a diagnosis. If your healthcare provider suspects nerve damage, he or she will take an extensive medical history and do a number of neurological tests to determine the location and extent of your nerve damage. These may include:

Depending on what basic tests reveal, your healthcare provider may want to do more in-depth scanning and other tests to get a better look at your nerve damage. Tests may include:

Usually a peripheral neuropathy cant be cured, but you can do a lot of things to prevent it from getting worse. If an underlying condition like diabetes is at fault, your healthcare provider will treat that first and then treat the pain and other symptoms of neuropathy.

In some cases, over-the-counter pain relievers can help. Other times, prescription medicines are needed. Some of these medicines include mexiletine, a medicine developed to correct irregular heart rhythms; antiseizure drugs, such as gabapentin, phenytoin, and carbamazepine; and some classes of antidepressants, including tricyclics such as amitriptyline.

Lidocaine injections and patches may help with pain in other instances. And in extreme cases, surgery can be used to destroy nerves or repair injuries that are causing neuropathic pain and symptoms.

Lifestyle choices can play a role in preventing peripheral neuropathy. You can lessen your risk for many of these conditions by avoiding alcohol, correcting vitamin deficiencies, eating a healthy diet, losing weight, avoiding toxins, and exercising regularly. If you have kidney disease, diabetes, or other chronic health condition, it is important to work with your healthcare provider to control your condition, which may prevent or delay the onset of peripheral neuropathy.

Even if you already have some form of peripheral neuropathy, healthy lifestyle steps can help you feel your best and reduce the pain and symptoms related to the disorder. Youll also want to quit smoking, not let injuries go untreated, and be meticulous about caring for your feet and treating wounds to avoid complications, such as the loss of a limb.

In some cases, non-prescription hand and foot braces can help you make up for muscle weakness. Orthotics can help you walk better. Relaxation techniques, such as yoga, may help ease emotional as well as physical symptoms.

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Peripheral Neuropathy | Johns Hopkins Medicine

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Peripheral Neuropathy | NIDDK

October 3rd, 2019 2:49 pm

In this section:

Peripheral neuropathy is a type of nerve damage that typically affects the feet and legs and sometimes affects the hands and arms.

This type of neuropathy is very common. Up to one-half of people with diabetes have peripheral neuropathy.1,2

Over time, high blood glucose, also called blood sugar, and high levels of fats, such as triglycerides, in the blood from diabetes can damage your nerves and the small blood vessels that nourish your nerves, leading to peripheral neuropathy.

If you have peripheral neuropathy, your feet, legs, hands, or arms may feel

You may feel extreme pain in your feet, legs, hands, and arms, even when they are touched lightly. You may also have problems sensing pain or temperature in these parts of your body.

Symptoms are often worse at night. Most of the time, you will have symptoms on both sides of your body. However, you may have symptoms only on one side.

If you have peripheral neuropathy, you might experience:

Peripheral neuropathy can cause foot problems that lead to blisters and sores. If peripheral neuropathy causes you to lose feeling in your feet, you may not notice pressure or injuries that lead to blisters and sores. Diabetes can make these wounds difficult to heal and increase the chance of infections. These sores and infections can lead to the loss of a toe, foot, or part of your leg. Finding and treating foot problems early can lower the chances that you will develop serious infections.

This type of diabetes-related nerve damage can also cause changes to the shape of your feet and toes. A rare condition that can occur in some people with diabetes is Charcots foot, a problem in which the bones and tissue in your foot are damaged.

Peripheral neuropathy can make you more likely to lose your balance and fall, which can increase your chance of fractures and other injuries. The chronic pain of peripheral neuropathy can also lead to grief, anxiety, and depression.

Doctors diagnose peripheral neuropathy based on your symptoms, family and medical history, a physical exam, and tests. A physical exam will include a neurological exam and a foot exam.

If you have diabetes, you should get a thorough exam to test how you feel in your feet and legs at least once a year. During this exam, your doctor will look at your feet for signs of problems and check the blood flow and feeling, or sensation, in your feet by

Your doctor may also check if you can feel temperature changes in your feet.

Your doctor may perform tests to rule out other causes of nerve damage, such as a blood test to check for thyroid problems, kidney disease, or low vitamin B12 levels. If low B12 levels are found, your doctor will do additional tests to determine the cause. Metformin use is among several causes of low vitamin B12 levels. If B12 deficiency is due to metformin, metformin can be continued with B12 supplementation.

You can prevent the problems caused by peripheral neuropathy by managing your diabetes, which means managing your blood glucose, blood pressure, and cholesterol. Staying close to your goal numbers can keep nerve damage from getting worse.

If you have diabetes, check your feet for problems every day and take good care of your feet. If you notice any foot problems, call or see your doctor right away.

Remove your socks and shoes in the exam room to remind your doctor to check your feet at every office visit. See your doctor for a foot exam at least once a yearmore often if you have foot problems. Your doctor may send you to a podiatrist.

Doctors may prescribe medicine and other treatments for pain.

Your doctor may prescribe medicines to help with pain, such as certain types of

Although these medicines can help with the pain, they do not change the nerve damage. Therefore, if there is no improvement with a medicine to treat pain, there is no benefit to continuing to take it and another medication may be tried.

All medicines have side effects. Ask your doctor about the side effects of any medicines you take. Doctors dont recommend some medicines for older adults or for people with other health problems, such as heart disease.

Some doctors recommend avoiding over-the-counter pain medicines, such as acetaminophen and ibuprofen. These medicines may not work well for treating most nerve pain and can have side effects.

Your doctor may recommend other treatments for pain, including

Diabetes experts have not made special recommendations about supplements for people with diabetes. For safety reasons, talk with your doctor before using supplements or any complementary or alternative medicines or medical practices.

[1] Pop-Busui R, Boulton AJ, Feldman EL, et al. Diabetic neuropathy: a position statement by the American Diabetes Association. Diabetes Care. 2017;40(1):136154.

[2] Izenberg A, Perkins BA, Bril V. Diabetic neuropathies. Seminars in Neurology. 2015;35(4):424430.

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Peripheral Neuropathy | NIDDK

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Peripheral neuropathy – Illnesses & conditions | NHS inform

October 3rd, 2019 2:49 pm

Treatment for peripheral neuropathymay includetreating any underlying cause or any symptoms you're experiencing.

Treatment may be more successfulfor certain underlying causes.For example,ensuringdiabetesis well controlled may help improve neuropathy or at least stop it getting worse.

There are many different possible causes of peripheral neuropathy, some of which can be treated in different ways. For example:

Some less common types of peripheral neuropathy may be treated with medication, such as:

However, the underlying cause may not always be untreatable.

You may also require medication to treat any nerve pain (neuropathic pain)you're experiencing.

Unlike most other types of pain, neuropathic pain doesn't usually get better with common painkillers, such as paracetamol andibuprofenand other medications areoften used.

These should usually be started at the minimum dose, with the dose gradually increased until you notice an effect, becausethe ideal dose for each person is unpredictable. Higher doses may bebetter at managing the pain, but are also more likely to cause side effects.

The most common side effects are tiredness, dizziness or feeling "drunk". If you get these, it may be necessary to reduce your dose. Don't drive or operate machineryif you experience drowsiness or blurred vision. You also may become more sensitive to the effects of alcohol.

The side effects should improve after a week or two as your body gets used to the medication. However, if your side effects continue, tell your GPas it may be possible to change to a different medication that suits you better.

Even if the first medication tried doesn't help, others may.

Many of these medications may also be used for treating other conditions, such as depression, epilepsy, anxiety or headaches. If you're given an antidepressant, this may treat pain even if you're not depressed.This doesn't mean your doctor suspects you're depressed.

The main medications recommended for neuropathic pain include:

There are also some additional medications that can be used to relieve pain in a specific area of the body or to relieve particularly severe pain for short periods. These are described below.

If your pain is confined to a particular area of your body and you can't, or would prefer not to,take the medications above, you may benefit from using capsaicin cream.

Capsaicin is the substance that makes chilli peppers hot and is thought to work in neuropathic pain by stopping the nerves sending pain messages to the brain.

A pea-sized amount of capsaicin cream is rubbed on the painful area of skin three or four times a day.

Side effects of capsaicin cream can include skin irritation and a burning sensation in the treated area when you first start treatment.

Don't use capsaicin cream on broken or inflamed skin and always wash your hands after applying it.

This is a large sticking plaster that contains a local anaesthetic. It's useful when pain affects only a small area of skin. It's stuck over the area of painful skin and the local anaesthetic is absorbed into the skin that's covered.

Tramadol is a powerful painkiller related to morphine that can be used to treat neuropathic pain that doesn't respond to other treatments your GP can prescribe.

Like all opioids, tramadol can be addictive if it's taken for a long time. It will usually only be prescribed for a short time.Tramadol can be useful to take at times when your pain is worse.

Common side effects of tramadol include:

In addition to treating pain, you may also require treatment to help you manage other symptoms you're experiencing as a result of peripheral neuropathy.

For example, if you have muscle weakness, you may need physiotherapyto learn exercises to improve your muscle strength. You may also need to wear splints to support weak ankles or use walking aids to help you get around.

Other problems associated with peripheral neuropathymay be treatable with medication, such as:

In some cases, you may need more invasive treatment, such as botulinum toxin injections for hyperhidrosisor urinary catheterisation if you have problems emptying your bladder.

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Polyneuropathy – Wikipedia

October 3rd, 2019 2:49 pm

Polyneuropathy (poly- + neuro- + -pathy) is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain.[3] It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, including diabetes and some types of GuillainBarr syndrome.[4][5][6]

Polyneuropathies may be classified in different ways, such as by cause,[1] by presentation,[3] or by classes of polyneuropathy, in terms of which part of the nerve cell is affected mainly: the axon, the myelin sheath, or the cell body.[7][8]

Among the signs/symptoms of polyneuropathy, which can be divided (into sensory and hereditary) and are consistent with the following:[3]

The causes of polyneuropathy can be divided into hereditary and acquired and are therefore as follows:[1]

In regards to the pathophysiology of polyneuropathy, of course, the former depends on which polyneuropathy. For instance in the case of chronic inflammatory demyelinating polyneuropathy, one finds that it is a autoimmune disease. Here, T cells involvement has been demonstrated, while in terms of demyelination, antibodies alone are not capable.[16]

The diagnosis of polyneuropathies begins with a history and physical examination to ascertain the pattern of the disease process (such as-arms, legs, distal, proximal) if they fluctuate, and what deficits and pain are involved. If pain is a factor, determining where and how long the pain has been present is important, one also needs to know what disorders are present within the family and what diseases the person may have. Although diseases often are suggested by the physical examination and history alone, tests that may be employed include: electrodiagnostic testing, serum protein electrophoresis, nerve conduction studies, urinalysis, serum creatine kinase (CK) and antibody testing (nerve biopsy is sometimes done).[3][2]

Other tests may be used, especially tests for specific disorders associated with polyneuropathies, quality measures have been developed to diagnose patients with distal symmetrical polyneuropathy (DSP).[17]

In terms of the differential diagnosis for polyneuropathy one must look at the following:

In the treatment of polyneuropathies one must ascertain and manage the cause, among management activities are: weight decrease, use of a walking aid, and occupational therapist assistance. Additionally BP control in those with diabetes is helpful, while intravenous immunoglobulin is used for multifocal motor neuropathy.[3]

According to Lopate, et al., methylprednisolone is a viable treatment for chronic inflammatory demyelinative polyneuropathy (which can also be treated with intravenous immunoglobulin). The authors also indicate that prednisone has greater adverse effects in such treatment, as opposed to intermittent (high-doses) of the aforementioned medication.[3][21]

According to Wu, et al., in critical illness polyneuropathy supportive and preventive therapy are important for the affected individual, as well as, avoiding (or limiting) corticosteroids.[22]

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The best Ophthalmologists in 2019 | TopDoctors

October 3rd, 2019 2:47 pm

What is ophthalmology?Ophthalmology is a branch of medicine which deals with the eyes and visual system, and diagnosing, treating, and preventing diseases and conditions affecting them.Ophthalmology is a mixed medical and surgical specialty, and deals with a diverse range of issues. Eye health services are very important, as eye problems, such as cataracts, are very common, affecting a large number of people across the UK, and as the population ages, the incidence of age-related macular degeneration (AMD) increases. If these diseases are caught early enough, they can be treated and managed with the expertise of ophthalmologists.What conditions does an ophthalmologist treat?Although the eye is a small organ, its importance cannot be overstated, and, due to the complexity of our visual mechanics, the eyes can be affected by a number of different problems and diseases. As such, ophthalmologists have to be trained to deal with a wide variety of visual problems. Some of these eye problems are very common for instance, cataract surgery is the second most common operation performed on the NHS in England.Some of the conditions ophthalmologists treat include:Which subspecialties are included under ophthalmology?Sub-specialty interests for ophthalmologists include:

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Advanced Eye Care | UK HealthCare

October 3rd, 2019 2:47 pm

If you are experiencing an eye emergency involving sudden vision loss or the acute onset of pain or double vision, call 911 or seek emergency care immediately. The UK Chandler Emergency Department has ophthalmology providers on call 24/7.

UK Advanced Eye Care provides expert eye care for all ages ranging from simple eye exams to diagnosing and treating the most complex eye diseases in a new state-of-the art facility.

Using the widest range and most up-to-date technology in the state, our fellowship-trained specialists are able to diagnose and treat various eye diseases and conditions including:

Having our entire team of optometrists, general ophthalmologists and specialists together in one location allows for improved efficiency, increased continuity of care, and ease of referrals for further testing, surgical consultation or treatment.

At UK Advanced Eye Care, we are proud of our patient care services. We are hiring full-time ophthalmic technicians and patient care coordinators. We offer competitive benefits and on-the-job training.

Contact Philip Moss if you are interested: 859-323-0729 or philip.moss@uky.edu.

Shriners Hospitals for Children Medical Center Lexington

110 Conn TerraceFourth and Fifth FloorsLexington, KY 40508

(Primary eye care and all subspecialty eye care)

UK HealthCare - Turfland

2195 Harrodsburg RoadFirst floorLexington, KY 40504

Monday - Friday: 8:00 am-5:00 pm

(Primary eye care)

PLEASE NOTE: UK Optical Shops at Shriners and Turfland are CLOSED. The providers of General Ophthalmology are still seeing patients as scheduled. See full notice

UK HealthCare Jessamine Eye Center

100 John Sutherland DriveSuite 3Nicholasville, KY 40356

UK Manchester Eye Care

231 White St.Manchester, KY 40962

(Primary eye care, retina and vitreous disorders)

UK HealthCare Eye Center - Richmond

920 Barnes Mills RoadSuite DRichmond, KY 40475

(Cornea and external diseases, glaucoma, pediatric ophthalmology, primary eye care, retina and vitreous disorders)

UK HealthCare - Baptist Health

1760 Nicholasville RoadSuite 203Lexington, KY 40503

(Corneal and external diseases, primary eye care, retina and vitreous disorders)

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Advanced Eye Care | UK HealthCare

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Genetics of Diabetes | ADA

October 3rd, 2019 2:47 pm

You've probably wondered how you developed diabetes. You may worry that your children will develop it too.

Unlike some traits, diabetes does not seem to be inherited in a simple pattern. Yet clearly, some people are born more likely to develop diabetes than others.

Type 1 andtype 2 diabeteshave different causes. Yet two factors are important in both. You inherit a predisposition to the disease, then something in your environment triggers it.

Genes alone are not enough. One proof of this is identical twins. Identical twins have identical genes. Yet when one twin hastype 1 diabetes, the other gets the disease at most only half the time. When one twin has type 2 diabetes, the other's risk is at most 3 in 4.

In most cases of type 1 diabetes, people need to inherit risk factors from both parents. We think these factors must be more common in whites because whites have the highest rate of type 1 diabetes.

Because most people who are at risk do not get diabetes, researchers want to find out what the environmental triggers are. One trigger might be related to cold weather. Type 1 diabetes develops more often in winter than summer and is more common in places with cold climates. Another trigger might be viruses. Perhaps a virus that has only mild effects on most people triggers type 1 diabetes in others.

Early diet may also play a role. Type 1 diabetes is less common in people who were breastfed and in those who first ate solid foods at laterages.

In many people, the development of type 1 diabetes seems to take many years. In experiments that followed relatives of people with type 1 diabetes, researchers found that most of those who later got diabetes had certain autoantibodies in their blood for years before. (Antibodies are proteins that destroy bacteria or viruses. Autoantibodies areantibodies'gone bad' that attack the body's own tissues.)

If you are a man with type 1 diabetes, the odds of your child developing diabetes are 1 in 17. If you are a woman with type 1 diabetes and your child was born before you were 25, your child's risk is 1 in 25; if your child was born after you turned 25, your child's risk is 1 in 100.

Your child's risk is doubled if you developed diabetes before age 11. If both you and your partner have type 1 diabetes, the risk is between 1 in 10 and 1 in 4.

There is an exception to these numbers. About 1 in every 7 people with type 1 diabetes has a condition called type 2 polyglandular autoimmune syndrome. In addition to having diabetes, these people also have thyroid disease and a poorly working adrenalgland. Some also have otherimmune systemdisorders. If you have this syndrome, your child's risk of getting the syndromeincluding type 1 diabetesis 1 in 2.

Researchers are learning how to predict a person's odds of getting diabetes. For example, most whites with type 1 diabetes have genes called HLA-DR3 or HLA-DR4. If you and your child are white and share these genes, your child's risk is higher. (Suspect genes in other ethnic groups are less well studied. The HLA-DR7 gene may put African Americans at risk, and the HLA-DR9 gene may put Japanese at risk.)

Other tests can also make your child's risk clearer. A special test that tells how the body responds toglucosecan tell which school-aged children are most at risk.

Another more expensive test can be done for children who have siblings with type 1 diabetes. This test measures antibodies toinsulin, to islet cells in thepancreas, or to anenzymecalled glutamic acid decarboxylase. High levels can indicate that a child has a higher risk of developing type 1 diabetes.

Type 2 diabetes has a stronger link to family history and lineage than type 1, and studies of twins have shown that genetics play a very strong role in the development of type 2 diabetes.

Yet it also depends on environmental factors.Lifestyle also influences the development of type 2 diabetes.Obesitytends to run in families, and families tend to have similar eating and exercise habits.

If you have a family history of type 2 diabetes, it may be difficult to figure out whether your diabetes is due to lifestyle factors or genetic susceptibility. Most likely it is due to both. However, dont lose heart. Studies show that it is possible to delay or prevent type 2 diabetes by exercising and losing weight.

Have you recently been diagnosed with type 2 diabetes?Join our free Living With Type 2 Diabetes program and get the information and support you need to live well with diabetes.

Type 2 diabetes runs in families. In part, this tendency is due to children learning bad habitseating a poor diet, not exercisingfrom their parents. But there is also a genetic basis.

If you would like to learn more about the genetics of all forms of diabetes, the National Institutes of Health has publishedThe Genetic Landscape of Diabetes. This free online book provides an overview of the current knowledge about the genetics of type 1 and type 2 diabetes, as well other less common forms of diabetes. The book is written for healthcare professionals and for people with diabetes interested in learning more about the disease.

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Ph.D. in Genetics at Texas A&M University

October 3rd, 2019 2:47 pm

Please save the date for oursecond Career Club of the fall semester!We are very excited to listen to Dr. Robyn Baldens talk about: Medical Science Liaison and other opportunities at Merck nextFriday,September 20th at12:00 PMinNMR/Rm. N127

Dr. Balden is a physician scientist and Regional Medical Scientific Director for Anesthesia/Surgery, South/Central US Medical Affairs division of Merck Research Labs. This role integrates internal and external scientific exchange and collaboration in order to facilitate and support clinical and drug development programs and maximize patient safety and outcomes related to existing pharmaceuticals including clinical trials, investigator-initiated studies, medical education, and scientific content creation.Her role at Merck began in 2018 as Associate Director, Medical Science Liaison for Anesthesia/Surgery, South/Central US, subsequent to gaining experience conducting medical research and directing business development for clinical trials at the Texas Center for Drug Development in Houston, TX. At the Texas Center for Drug Development she engaged in medical affairs focusing on coordination of clinical research for various therapeutic areas, serving as a supporting investigator for clinical trials, scientific discussion and account management with key physician leaders, and development of medical educational materials. Prior to this role she was a surgical intern, resident anesthesiologist, and clinical scholar at Cedars-Sinai Medical Center in Los Angeles, CA, where she initiated clinical studies for novel anesthetic regimens.

Dr. Balden received her MD and PhD in Neuroscience from Texas A&M Health Science Center College of Medicine. Her passions involve the intersection of medicine and science with neuroimmunology and neuroendocrinology. She also collaborates with advocacy and student organizations, has written several academic papers on Vitamin D, and served as a member of the Vitamin D Councils Board of Directors contributing as a volunteer writer, podcast contributor, and graphic designer for the Vitamin D Council. Shelives with her family in Houston, TX and enjoys painting, design, traveling, scuba diving, outdoors, live music, reading, cooking, and gardening.

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Ph.D. in Genetics at Texas A&M University

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A Quick History of Veterinary Medicine | CANIDAE

October 3rd, 2019 2:46 pm

By Linda Cole

Modern day veterinarians have an essential role in the health and welfare of our pets, as well as livestock and wildlife. Vets are well-versed in the science of animal health, and they promote public health by identifying and combating infectious zoonotic diseases that can be passed from animals to humans. Advances in medical science have provided veterinary professionals with sophisticated equipment, tests, procedures and medicines to treat our pets. However, the history of veterinary science dates back much further than you may realize.

The first known people to dabble in the field of veterinary medicine began around 9000 BC in Middle East countries including Saudi Arabia, Egypt, Iran, Turkey and Iraq. Sheepherders had a crude understanding of medical skills which were used to treat their dogs and other animals. From 4000 to 3000 BC, Egyptians took earlier medical skills and made further advancements. Historical records and Egyptian hieroglyphs record how they used herbs to treat and promote good health in domesticated animals.

Vedic literature, which was written around 1500 BC, refers to four sacred texts from India written in the Sanskrit language that forms the basis of the Hindu religion. The Kahun Papyrus from Egypt dates back to 1900 BC. Both texts are likely the first written accounts of veterinary medicine. One of the sacred texts documents Indias first Buddhist king, Asoka, who ensured there were two kinds of medicine: one for humans and one for animals. If he discovered there was no medicine available for one or the other, he ordered healing herbs to be bought and planted where they were needed.

The Kahun Papyrus is the oldest known papyrus medical text. Its divided into 34 sections that deal with specific topics. One of the topics is animal gynecology. Tomb drawings predating the Kahun Papyrus by a couple thousand years document early Egyptian understanding of gynecology. Trained specialists were skilled obstetricians and given the name of overseer of cattle. They were charged with examining cattle, attending to pregnancies, and the birthing of calves to ensure their health and survival.

Archaeologists found fragments of a papyrus that was a medical textbook from somewhere around 1850 BC, indicating that Egyptians were familiar with the anatomy of animals, could recognize early warning signs of certain diseases in dogs, birds, fish and cattle, and used specific treatments to deal with them. The Romans, Greeks, Babylonians, Hindus, Arabs and Hebrews also practiced animal medicine. A man named Urlugaledinna, who lived in Mesopotamia in 3000 BC, was considered an expert in his ability to heal animals. Around 500 BC, a Greek scientist named Alcmaeon dissected animals to study them.

Early attempts to regulate and organize the treatment of animals were mainly focused on horses because of their economic importance to society. During the Middle Ages, farriers combined their trade of horseshoeing with general horse doctoring. When the Lord Mayor of London, which is different from the Mayor of London, learned about the poor care horses in London were receiving in 1356, he persuaded all farriers within a seven mile radius of the city to form a fellowship to improve and regulate how they treated horses. The fellowship led to the creation in 1674 of the Worshipful Company of Farriers.

The first veterinary school was founded in Lyon, France in 1761 by Claude Bourgelat, and thats when the profession of veterinary medicine officially began. The school focused on studying the anatomy and diseases of sheep, horses and cattle in an effort to combat cattle deaths from a plague in France. Cattle plagues were common throughout history, but attempts to learn how to fight microorganisms had to wait until the invention of the microscope sometime in the 1590s. The first vaccinations for cattle were developed in 1712 and used to eradicate a plague in Europe.

Over the next ten years, veterinary schools were established in Germany, Sweden and Denmark. In 1791, the London Veterinary College was established and developed veterinary science at a professional level dedicated to animal medicine. The wellbeing and health of horses was their initial focus for years, because of the use of horses in the Army. Eventually they turned their attention to cattle and other livestock, and finally added dogs and other animals.

The first veterinary school established in the United States was the Veterinary College of Philadelphia in 1852, which operated until 1866. In 1883, the School of Veterinary Medicine at the University of Pennsylvania was established and is the oldest accredited veterinary school still in operation. The American Veterinary Medical Association (AVMA) was established in 1863, and the Bureau of Animal Industry under the USDA was set up in 1884 and in operation until 1900. Its purpose was to protect the public from infectious diseases through contaminated meat, eradicate diseases in animals and improve the quality of livestock.

Top photo by Bainbridge Bethesda/FlickrBottom photo by Anne Worner/Flickr

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Stem Cell Therapy For Knees | Relief Without Surgery!

October 2nd, 2019 7:51 pm

Have you been told that steroid injections or invasive surgery are your only options to treat your knee pain? Interventional orthopedics provides a non-surgical alternative that uses your own cells to repair the damage.

Recent researchshows that some of the most popularorthopedic kneesurgeriesincluding meniscectomies have no benefit and are not more effective than placebo or sham surgery. Moreover, knee replacement is extremely traumatic and carries associated risks, and even successful surgeries minimally require months of painful rehab to regain strength and mobility. Most surgeries also accelerate degeneration that leads toosteoarthritis and exacerbate the biomechanical problems that initially led to the need for the surgery. Regenexx urges patients suffering from knee injuries or degenerative conditions to consider all of their options.

At Regenexx we inventeda new approachto orthopedic care we call Interventional Orthopedics. This approach involves the use ofimage guidance (flouroscopy and ultrasound) to precisely placehigh-dose stem cells or platelets from your body directly where they are needed in a specific joint structure. These cells then work in the site of your injury to grow into new, healthy tissue, a process that will only occur if the cells have been placed exactly where they need to go in order to achieve positive outcomes for the patient.This precise approach to orthopedic care cant be replicated by a surgeon or nurse in a chiropractors office. Interventional Orthopedics requiresthousands of hours of trainingfollowing a standardized protocol process to become a licensed Regenexx physician.

The innovative Regenexx procedures restore knee function and mobility and decrease pain without the need for surgery by regenerating damaged tissue. Duringthis outpatient procedure, ourexpert physiciansuseprecise image guidanceto injectcustom concentrationsofyour bodys natural healing agentsinto the exact areas of damage to tighten and stabilize your knee joint for better function and mobility.

This page contains an extensive library of educational resources on kneeconditions and our patented kneeprocedures created by Regenexx and our founder, Chris Centeno, M.D.. We encourage you to research your options.

GET RELIEF. 855-330-5818

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