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Stem Cell Treatment & Therapy for Diabetes Type 2 in …

March 16th, 2019 11:49 am

Overview

For people suffering from Type 2 diabetes, stem cell therapy can offer a respite from the symptoms of the disease. Although stem cell therapy cannot cure it, receiving stem cell therapy for diabetes Type 2 from TruStem Cell Therapy has the potential to improve a patients quality of life significantly by reducing symptoms and complications related to Type 2 diabetes, as well as slowing its progression.

For patients receiving stem cell diabetes treatment, it is possible to see improvements in any one or multiple disease-related complications such as stabilization of blood sugar levels, lower blood sugar levels, frequent urination, fatigue, poor wound healing, etc.

TruStem Cell Therapy provides access to diabetes treatment that utilizes a patients stem cells isolated from his or her own fat tissue. There are multiple benefits afforded by the utilization of adipose-derived stem cells, including their ability to differentiate into a broad variety of cell types (neurons, bone, cartilage, muscle, tendon, etc.), they are present at comparatively much higher levels than other stem cell types; possess higher immunomodulatory capacity; and they do not endanger a patients health the way other stem cells might.

There are three steps to the treatment process:

Approximately 150 to 250 ccs of a patients own fat tissue is harvested through a minimally invasive procedure. Generally, this fat tissue is collected from around the patients belly region.

Typically, patients will experience some soreness and bruising lasting roughly a week as a result of the harvesting procedure. Additional complications from stem cell therapy for diabetes have not been observed. Although the FDA has not approved stem cell therapy for diabetes Type 2 as of yet, more than 100 studies and clinical trials have demonstrated the safety and minimal side effect profile of stem cell therapy.

Because every patient responds differently to treatment, it is difficult to predict the timeline of a patients response. It could take weeks to months for stem cell therapy for diabetes Type 2 to provide noticeable results.

Our focus is on safety, efficacy and patient-centric care when providing access to superior stem cell therapy. We utilize only board-certified surgeons, physicians and accredited clinicians to provide care for patients. Our laboratory protocols are developed and refined by our PhD neuroscientist, and our clinical team has extensive expertise in practicing cellular-based medicine. Our accredited surgical centers are geared toward enhanced procedural and patient safety. Above all, TruStem Cell Therapy has skilled patient advocates who are trained to provide truthful, realistic expectations resulting from stem cell therapy. We do not make outlandish promises of cures, or inaccurate claims related to improvement rates.

Type 2 diabetes is a relatively common disorder that causes high blood sugar levels. Though it may sound innocuous, high blood sugar can lead to symptoms like frequent urination, increased thirst and blurred vision; as well as more severe health-related complications, including fatigue, cardiovascular disease, stroke and kidney failure.

Type 2 diabetes develops when the body becomes resistant to or stops producing insulin: a hormone that helps remove sugar from blood and allows it to be absorbed into various tissue types like muscle and fat. Exactly why this happens is unknown, although genetics and environmental factors such as excess weight and inactivity seem to be contributing factors.

Living with Type 2 diabetes can be difficult, but TruStem Cell Therapy may be able to help you live a more comfortable and fulfilling life through stem cell diabetes treatment. If youd like to learn more about how we might be able to help you, contact us today.

Symptoms/Complications

Frequent urination

Increased thirst and hunger

Blurred vision

Fatigue

Cardiovascular disease

Stroke

Blindness

Kidney failure

Lower limb amputations

Causes

Type 2 diabetes develops when the body becomes resistant to insulin or when the pancreas stops producing enough insulin. Exactly why this happens is unknown, although genetics and environmental factors, such as excess weight and inactivity, seem to be contributing factors.

TruStem Cell Therapy

TruStem Cell Therapy provides access to treatment that utilizes a patients stem cells isolated from their own fat tissue. There are multiple inherent benefits afforded by the utilization of adipose derived stem cells including their ability to differentiate into a broad variety of cells types (neurons, bone, cartilage, muscle, tendon, etc.), they are present at comparatively much higher levels than other stem cell types, possess higher immunomodulatory capacity, and they do not endanger a patients health the way other stem cells might.

Approximately 150-250ccs of a patients own fat tissue is harvested through a minimally invasive, mini liposuction procedure. Generally, this fat tissue is collected from around the patients belly region.

Harvested fat tissue is immediately taken to the onsite laboratory for processing. At this step, an optimized protocol is used to isolate the maximum number of stem cells from collected fat tissue.

TruStem Cell Therapy utilizes both systematic and novel administration methods to fully saturate the body with stem cells while targeting specific areas of injury.

DT2 patients who receive stem cell therapy through us can receive multiple systemic and targeted administration methods:

Intravenously ADSCs are delivered via a vein for distribution throughout the body

Direct site injections ADSCs are delivered to sites that need repair, such asIschemic limbs andNeuropathy or nerve damage to various areas of the body.

Our focus is safety, efficacy, and patient-centric care when providing access to superior stem cell therapy.

We utilize only board certified surgeons, physicians and accredited clinicians to provide care for patients.

Laboratory protocols are developed and refined by our PhD Neuroscientist.

A clinical team with expertise in practicing cellular based medicine.

Accredited Surgical Centers for enhanced procedural and patient safety

Targeted administration methods that direct stem cells toward specific

Skilled Patient Advocates who are trained to provide truthful, realistic expectations resulting from stem cell therapy. We do not make outlandish promises of cures or inaccurate claims related to improvement rates.

FAQ

Unfortunately, not at this time. We are only providing access to stem cell therapy for Type 2 Diabetes. To date there is not enough research or clinical evidence to support the use of adult stem cell therapy as an effective therapy option for patients with type 1 diabetes. However, this may change with future advances so please return for updates on this matter.

It is important for patients and caregivers to understand that current therapies, including stem cell treatment, does not provide a cure for type 2 diabetes. However, TruStem Cell Therapy does have the potential to improve a patients quality of life by reducing symptoms and complications related to type 2 diabetes as well as slowing its progression.

The FDA has not approved stem cell therapy for type 2 diabetes. As noted above, studies have demonstrated the safety and efficacy of stem cell therapy for this condition but additional studies are needed before FDA approval can be secured.

It is possible through these treatments, to improve a patients quality of lifebyminimizing disease relatedsymptoms and complications. For Type II Diabetes patients, it is possible to see improvements in any one ormultipledisease related complications such as: stabilization of blood sugar levels, lower blood sugar levels, frequent urination, fatigue, poor wound healing, etc If you have questions regarding how these treatments may help you, please contact one of our Patient Advocates to learn more.

It is difficult to predict the timeline of a patients response. Every patient responds differently to treatment. It could take weeks to months for the stem cells to provide noticeable results.

Typically patients will experience some level of soreness and bruising lasting roughly a week as a result of the mini-liposuction procedure. Additional complications have not been observed. Over a hundred studies and clinical trials have demonstrated the safety and minimal side-effect profile of stem cell therapy.

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South Florida Stem Cell Center | Regenerative Therapy Clinic

March 16th, 2019 11:49 am

Cardiac-Pulmonary Conditions

Led by Melvin M. Propis, M.D., South Florida Stem Cell Center is one of theleading Stem Cell Regenerative Therapy Clinics in South Florida. Dr. Propis is a seasoned M.D. and surgeon who has had solid success rates.

Stem Cell Regenerative Therapy is a breakthrough in medical science that treats and prevents conditions and diseases using stem cells. This is accomplished by harvesting cells and then concentrating those cells in a lab before precisely re-injecting them. This greatly increases your bodys own natural repair cells and promotes healing.

South Florida Stem Cell Center is made up of research scientists and experts in Stem Cell Therapy.Our passion and belief is that our treatments truly helpthose that are suffering and need our help.

Maribella MKnee Injury

I injured both of my knees. After confirming that the cartilage was still in the joint, Dr. Propis injected my knees with a mixture of stem cells and PRP 4 months ago. Today I walk comfortably, No pain in those joints. I have noticed significant improvement in my balance and no longer need a walker or narcotics for pain.

Mia HCrohn's Disease

I have had Crohns disease for most of my short life which has led me to miss out on many teenage activities. After seeing other patients improve from having stem cells injected, I (and my mother) decided to try it. It was a wonderful thing to gradually be able to discontinue giving myself Humara shots routinely. I can actually have an active social life without worrying and even married the love of my life last year. Thanking my doctor, mom, God, and the many people who believe in stem cells for my happy ending!

George BDiabetes

I flew to the US in hopes of getting help for my diabetes. Having tried medicine & diets with no results, I was ready to try stem cells. After 1 treatment (and a six month period) I am off all meds and not considered diabetic anymore. To me, life changing! Especially after a relatively simple procedure. Thank you to the office of Dr. Propis and staff.

We Specialize In Treating:

Immunological Conditions

A chronic inflammatory bowel disease that affects the lining of the digestive tract.

Widespread muscle pain and tenderness.

A chronic inflammatory disorder affecting many joints, including those in the hands and feet.

An inflammatory disease caused when the immune system attacks its own tissues.

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Neurological Conditions

A congenital disorder of movement, muscle tone, or posture.

Damage to the brain from interruption of its blood supply.

A progressive disease that destroys memory and other important mental functions.

A disease in which the immune system eats away at the protective covering of nerves.

A disorder of the central nervous system that affects movement, often including tremors.

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Degenerative Conditions

Damage to any part of the spinal cord or nerves at the end of the spinal canal.

A chronic condition that affects the way the body processes blood sugar (glucose).

Kidney Failure (Renal Failure)

A condition in which the kidneys lose the ability to remove waste and balance fluids.

A type of arthritis that occurs when flexible tissue at the ends of bones wears down.

Occurs when a man can't get or keep an erection firm enough for sexual intercourse.

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Stem cell research – novonordisk.com

March 16th, 2019 11:47 am

The fertilised egg is the only (totipotent) stem cell that can give rise to a human being. Cells found in the early embryo (the blastomeres and the inner cell mass of the blastocyst) can give rise to pluripotent embryonic stem cell cultures that maintain the ability to mature into all the different cell types found in the fully developed body.

Stem cells in the adult body (adult stem cells or tissue-specific stem cells) are used by the body to replace old and damaged cells. As opposed to pluripotent stem cells, adult stem cells can normally only mature into a limited number of specialised cell types (multipotent). Therefore, Novo Nordisk focuses on pluripotent stem cells as a basis for cell therapy.

Research on adult stem cells has been taking place for more than 30 years, and has not been subject to ethical objections, whereas research on stem cells obtained from surplus embryos donated with freely given informed consent is a central issue in the ongoing ethical debate, because the embryo is lost in the process of establishing one continuous cell line. However, new scientific findings show that a human embryonic stem cell line can be established from one single cell of the blastomere stage without affecting the vitality of the embryo. This technique can also be used to generate human embryonic stem cell lines from non-viable blastocysts (which are discarded anyway by IVF clinics).

Currently, the best defined and most extensively used stem cell treatments are based on adult stem cells, including blood stem cell transplantation to treat diseases and conditions of the blood and immune system. Pluripotent stem cells themselves cannot directly be used for therapies as in their undifferentiated state. They will first need to be coaxed into specialised cell types before transplantation. Therefore, it is critical that these cells are proven safe and efficacious in preclinical and controlled clinical trials. Many potential stem cell-based treatments are currently being tested in animal models and a few have been brought to clinical trials, with the first phase 1/2 clinical trial approved by the US Food and Drug Administration (FDA) in 2010.

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Gene Therapy Basics | Education | ASGCT American Society …

March 16th, 2019 11:47 am

Gene therapy has been studied for more than 40 years and can help stop or slow the effects of disease on the most basic level of the human bodyour genes. And to understand how it works, well start at the basics.

Genes are made up of DNA, which are blueprints to build enzymes and proteins that make our body work. As far as we know, humans have between 20,000 and 25,000 genes. We typically get two copies of each gene from our parents. They influence everything from the color of our hair to our immune system, but genes arent always built correctly. A small adjustment to them can change how our proteins work, which then alter the way we breathe, walk or even digest food. Genes can change as they go through inherited mutations, as they age, or by being altered or damaged by chemicals and radiation.

In the case that a gene changesalso known as mutatingin a way that causes disease, gene therapy may be able to help. Gene therapy is the introduction, removal or change in genetic materialspecifically DNA or RNAinto the cells of a patient to treat a specific disease. The transferred genetic material changes how a proteinor group of proteinsis produced by the cell.

This new genetic material or working gene is delivered into the cell by using a vector. Typically, viruses are used as vectors because they have evolved to be very good at sneaking into and infecting cells. But in this case, their motive is to insert the new genes into the cell. Some types of viruses being used are typically not known to cause disease and other times the viral genes known to cause disease are removed. Regardless of the type, all viral vectors are tested many times for safety prior to being used. The vector can either be delivered outside the body (ex-vivo treatment) or the vectors can be injected into the body (in-vivo treatment).

Other types of drugs are typically used to manage disease or infection symptoms to relieve pain, while gene therapy targets the cause of the disease. It is not provided in the form of a pill, inhalation or surgery, it is provided through an injection or IV.

What Counts as a Rare Disease?

Gene therapy treats diseases in patients that are rare and often life threatening. Rare is defined as any disease or disorder affecting fewer than 200,000 people in the U.S. by the National Institutes of Health. As of now, there are around 7,000 rare diseases, affecting a total of approximately one in ten people. Many of these rare diseases are caused by a simple genetic mutation inherited from one or both parents.

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Which Diseases Have Gene Therapies?

Of gene therapies up for approval over the next five years, 45 percent are anticipated to focus on cancer treatments and 38 percent are expected to treat rare inherited genetic disorders. Gene therapy can help add to or change non-functioning genescreating a great opportunity to assist with rare inherited disorders, which are passed along from parents. The mutation might be present on one or both chromosomes passed along to the children. The majority of gene therapies are currently being studied in clinical trials.

Some of these inherited diseases include (but are not limited to):

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Why Do We Use Viral Vectors?

As you know from cold and flu season, viruses are quite skilled in the art of invading our bodiesadding their genetic material into our cells. However, researchers have learned to harness this sneaky ability to our advantage. Viruses are often used as a vehicle to deliver good genes into our cells, as opposed to the ones that cause disease.

Viruses are sometimes modified into vectors as researchers remove disease-causing material and add the correct genetic material. In gene therapy, researchers often use adeno-associated viruses (AAV) as vectors. AAV is a small virus that isnt typically known to cause disease in the first place, significantly reducing a chance of a negative reaction.

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Molecular Genetics – University of Toronto

March 15th, 2019 1:44 pm

The Department of Molecular Genetics is administered from the Medical Sciences Building and has nearly 100 faculty members whose labs are located within the Medical Science Building, the Best Institute, the Donnelly Centre for Cellular and Biomolecular Research, the FitzGerald Building, the Hospital for Sick Children, Mount Sinai Hospital, the Ontario Institute for Cancer Research, and Princess Margaret Hospital.

The Master of Science and Doctor of Philosophy programs in Molecular Genetics offer research training in a broad range of genetic systems from bacteria and viruses to humans. Research projects include DNA repair, recombination and segregation, transcription, RNA splicing and catalysis, regulation of gene expression, signal transduction, interactions of host cells with bacteria and viruses, developmental genetics of simple organisms (worms and fruit flies) as well as complex organisms (mice), molecular neurobiology, molecular immunology, cancer biology and virology, structural biology, and human genetics and gene therapy.

Students may also be interested in the combined degree program inMedicine, Doctor of / Doctor of Philosophy (MD/PhD).

See video Explore Graduate Programs at the Faculty of Medicine

Molecular GeneticsMSc, MD/PhD, Ph

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How does gene therapy work? – Genetics Home Reference – NIH

March 15th, 2019 1:44 pm

Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. If a mutated gene causes a necessary protein to be faulty or missing, gene therapy may be able to introduce a normal copy of the gene to restore the function of the protein.

A gene that is inserted directly into a cell usually does not function. Instead, a carrier called a vector is genetically engineered to deliver the gene. Certain viruses are often used as vectors because they can deliver the new gene by infecting the cell. The viruses are modified so they can't cause disease when used in people. Some types of virus, such as retroviruses, integrate their genetic material (including the new gene) into a chromosome in the human cell. Other viruses, such as adenoviruses, introduce their DNA into the nucleus of the cell, but the DNA is not integrated into a chromosome.

The vector can be injected or given intravenously (by IV) directly into a specific tissue in the body, where it is taken up by individual cells. Alternately, a sample of the patient's cells can be removed and exposed to the vector in a laboratory setting. The cells containing the vector are then returned to the patient. If the treatment is successful, the new gene delivered by the vector will make a functioning protein.

Researchers must overcome many technical challenges before gene therapy will be a practical approach to treating disease. For example, scientists must find better ways to deliver genes and target them to particular cells. They must also ensure that new genes are precisely controlled by the body.

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The kidney repair shop | Harvard Stem Cell Institute (HSCI)

March 15th, 2019 1:42 pm

Regeneration is, of course, the Holy Grail of medicine. Many diseases are chronic because they are a consequence of damage to organs or tissues beyond any natural repair mechanism. When kidneys are damaged beyond repair, the only answer may be transplantation (severely restricted due to the scarcity of donors) or dialysis a terrible burden on patients (over 350,000 in the U.S.) who are forever tethered to their condition by weekly and sometimes daily visits to a machine. Harnessing the power of the kidneys innate ability to regenerate could enable patients to regain their health.

The kidney actually ranks very highly in its ability to repair itself, said Joseph Bonventre, MD, PhD Professor of Medicine at Harvard Medical School, Chief of the Renal Division at Brigham and Womens Hospital, and head of the HSCI Kidney Disease Program.

Bonventre and his team study the mechanisms by which the kidney repairs tissue after disease, particularly the repair of nephrons, which are the key functional units of the kidney. The nephron consists of a filtering unit for the blood, the glomerulus, and a complex tubule responsible for filtering the blood. The small tubules collect the filtrate and process it before passing it on to ducts leading to the bladder. If tubules are damaged they can be repaired but if the damage is severe enough the nephron may be destroyed. Unfortunately the kidney can regenerate and recover, but the kidney cannot make new nephrons, and in that context, its regeneration is limited.

What happens to the tubules is a clinically relevant question. In kidney disease, whether the disease starts in the filters or the tubules, the tubules ultimately become involved as they are highly susceptible to injury. A reduction in blood flow can lead to a restriction in the supply of oxygen, which can be lethal to the epithelial cells that form the lining of the tubules. For acute kidney injury, the tubules are often (but not always) capable of recovering completely. In chronic kidney failure, the injuries are progressive and nephrons are lost.

Many theories exist on kidney repair. Some suggest that the kidney may recruit circulating stem cells to migrate into and regenerate the damaged area, others that local tissue specific stem cells may be triggered to differentiate and rebuild, and still others that the kidney may forego a direct role for stem cells altogether by inducing mature cells to proliferate.However, a recent study by Bonventre, HSCI Affiliated Faculty member Benjamin Humphreys, MD, PhD, HSCI Executive Committee Member Andrew McMahon, PhD, and their team went a long way toward understanding how the tubules repair themselves.

By tagging the mature epithelial cells that form the tubule walls with a red fluorescent protein, the HSCI team was able to demonstrate that the replacement cells after injury are coming from the epithelium itself rather than from circulating stem cells that enter the kidney or local tissue specific stem cells in the tissue between the tubules. These stem cells might not be sitting on the sidelines, however. Other evidence suggests that they may be offering some assistance in causing the epithelial cells to multiply.

The Harvard Stem Cell Institute basically has allowed us to look at kidney disease in a different and, in many cases, quite definitive way. Joseph Bonventre, MD, PhD

In over 35 years of studying the repair of damaged kidneys, Bonventre suggests that the field may be reaching an inflection point. The Harvard Stem Cell Institute basically has allowed us to look at kidney disease in a different and, in many cases, quite definitive way, said Bonventre. Were understanding the processes much better so that we can now focus on the cell biology related to the intrinsic capacity for the kidney to renew itself.

Collaboration among HSCI researchers has been key to advancing this understanding by sharing expertise as well as findings from model organisms such as the mouse and the zebrafish. Andy McMahon is a world class investigator who has made enormous contributions to the understanding of the way the kidney matures during development, said Bonventre. It has been very productive to apply this knowledge to understanding repair in the adult organ. The team is also using knowledge of the kidneys ability to renew itself to find out how to protect it from further damage. We have found in mice that we can precondition the kidney to be protected against a subsequent injury simply by temporarily cutting off blood flow to parts of the organ and coming back one to two weeks later and finding that when we cut off blood supply again the kidney is not damaged, said Bonventre. We want to understand what causes the protection against the second injury. Is there a cell that goes into the kidney, or some other factor involved? If these protective factors can be found, they could potentially be developed as drugs or treatments that prevent kidney damage in highrisk individuals.

Another use of kidney cells grown in the laboratory is in screens for the potential toxicity of drugs before they are introduced into animals or humans. There really is no good model for in vitro kidney toxicity screening today, because the cells tend to lose their differentiated state and become less kidney-like or less epithelial-like outside the body. Bonventre and colleagues are working on ways to control cell behavior and maintain their state to make better predictive screens. We will be working with Lee Rubins group at the HSCI Therapeutic Screening Center to help us screen for molecules that will keep cells differentiated in culture. If we can do that, we can use them for toxicology and for more sophisticated kidney assist devices, said Bonventre.

Taking that technology back inside the body, one might even use the differentiated cells to create artificial tubules and nephrons with the help of bioengineered materials - completing the regeneration that the kidney is unable to do on its own.

Patients might not have to wait too long to see the benefits of this research. Based on animal studies that suggested an indirect role for stem cells in kidney repair, clinical trials aimed at preventing or rolling back kidney damage in cardiac patients have already begun.

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Personalized Medicine for Brain Tumors | Cleveland Clinic

March 14th, 2019 1:44 am

What is Personalized Medicine?

Genes are part of our DNA, or genetic blueprint. Personalized medicine is a way to gather information about the unique genetic makeup of your brain tumor that can help you and your physician decide on the best treatment plan for you.

Personalized medicine makes a more targeted approach to treatment possible. It provides data about sensitivities or resistance your tumor may have. It can determine how likely you are to respond to certain medicines, steering your doctor toward the safest, most effective choice whether an FDA-approved drug or one only available in a leading-edge clinical trial.

Personalized medicine is a simple, painless process. It involves taking only a small amount of tissue through a biopsy, which is sent for an analysis of the hundreds of known cancer genes. The results are available in two to three weeks. Your Cleveland Clinic physician will call you to discuss the findings and what they mean for your course of treatment.

Personalized medicine is extremely sensitive in finding all types of changes in genes, with no false positives. More than two-thirds of the changes it detects would not be able to be found by any other kind of testing. However, there is no guarantee that the testing will generate results that will be useful in guiding your therapy.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy

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Personalized Medicine – Coriell Personalized Medicine …

March 14th, 2019 1:44 am

Our health is determined by many factors, among them: the genetics we inherit; our race, age and gender; our lifestyle; and our socioeconomic environment. These factors differ for everyone and change over our lifespan. Also unique to everyone is their experience with disease and how they respond to prescription drugs or other medical therapies.

Personalized medicine is the use of genomic information in addition to family history, lifestyle, and environmental factors to customize health management. By combining genomic and clinical information, more accurate predictions can be made about a person's susceptibility of developing disease, the course of disease, and response to treatment.

When your genetic information informs your increased risk for a disease and you make lifestyle changes to reduce that risk, personalized medicine has revealed itself. If you have a gene variation that influences how you process a medication and your physician prescribes dosing instructions accordingly, your medical care is now safer, well-timed, accurate, and more cost-effective for you and our healthcare system.

Personalized medicine has the potential to offer patients and their doctors several advantages, including:

Personalized medicine is a relatively new field, and outcomes research and evidence-based literature is important to its integration into healthcare delivery. The Coriell Personalized Medicine Collaborative(CPMC) research study is contributing to both: CPMCstudy participants regularly complete follow-up questionnaires that explore how they are using the information they receive from the study, whether they are making lifestyle changes to reduce their disease risk or improving their medication response, and if they are sharing their results with family and healthcare providers. Additionally, Coriell has and will continue to publish scientific findings from the CPMCstudy, contributing to new medical literature.

Here on the Coriell research study website you will learn more about the utility of personalized medicine in clinical care, how physicians can prescribe medications that will be more efficient for you, and how the CPMCstudy is reporting many health conditions and drug responses to study participants.

For more information about personalized medicine, visit the follow sites:

The human body is composed of trillions of cells cells being the building blocks of all living things. [ Learn More ]

Pharmacogenomics is the study of genetic variation and medication response. [ Learn More ]

Learn how genetic information can be used in clinical decision-making and preventive care. [ Learn More ]

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What is the difference between precision medicine and …

March 14th, 2019 1:44 am

There is a lot of overlap between the terms "precision medicine" and "personalized medicine." According to the National Research Council, "personalized medicine" is an older term with a meaning similar to "precision medicine." However, there was concern that the word "personalized" could be misinterpreted to imply that treatments and preventions are being developed uniquely for each individual; in precision medicine, the focus is on identifying which approaches will be effective for which patients based on genetic, environmental, and lifestyle factors. The Council therefore preferred the term "precision medicine" to "personalized medicine." However, some people still use the two terms interchangeably.

Pharmacogenomics is a part of precision medicine. Pharmacogenomics is the study of how genes affect a persons response to particular drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that are tailored to variations in a persons genes.

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The Stem Cell Treatment Process – regenocyte.com

March 14th, 2019 1:44 am

Once you have decided this is the best option for you, we will determine if any other testing is needed which can be done at our facilities in Florida or wherever you live. We will then plan a date for your stem cell procedure in the Dominican Republic. The process begins with the extraction of bone marrow from the top of you pelvis and also from adipose tissue (fat) at the hospital. In our lab, the stem cells will be activated and multiplied by using naturally occurring growth factors. In this process of activation, the stem cells are customized for the purpose for which they will be used in treatment. For example, they can be activated to build muscle tissue for the heart, to rebuild blood vessels in the extremities or lungs or into neural cells for the central nervous system. This process is done overnight.

The following day the activated cells are returned to the patients body by a process which delivers the stem cells to the part of the body that is being treated. You will be informed of your actual reinsertion method as part of the course of treatment developed specifically for you and your injury or disease.

Once your procedure is completed you will spend anywhere from a few hours, to two days in the hospital depending on your specific treatment and your baseline condition. A full report regarding your procedure will be prepared by the treating physicians and will be sent home with you. You will be given follow up instructions and a schedule of follow-up tests to evaluate your progress. Periodically, you will be contacted by our patient care team with interpretation of your test results and to answer any questions you may have.

Our stem cell clinic will help coordinate all of your travel and transportation arrangements. You arrive at the Santo Domingo International Airport in the Dominican Republic and your transportation coordinator will be waiting for you just outside of the airport. They will have a placard with your name on it. Our team will coordinate with you while you are in the Dominican Republic, including transportation to and from the airport, the hotel, and the hospital.

Be advised that a valid passport is required for entry into the Dominican Republic. Information regarding obtaining a United States passport can be found at: The United States Department of State

We have successfully treated patients from all over the world. We pride ourselves in providing the best, most advanced treatment worldwide and look forward to talking with you, your family or friends regarding the possibility of having Regenocyte Stem Cell Therapy change your life.

To get started with evaluation or more information. Contact our stem cell clinic here or call us at (866) 216-5710

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Funding Clinical Trials | California’s Stem Cell Agency

March 12th, 2019 3:55 pm

Mark Humayun University of Southern California Phase 1 Active, not recruiting 16 Tippi MacKenzie University of California, San Francisco Phase 1 Recruiting 10 Ralph Kern BrainStorm Cell Therapeutics Phase 3 Recruiting 200 Clive Svendsen Cedars-Sinai Medical Center Phase 1/2 Active, not recruiting 18 Crystal Mackall Stanford University Phase 1 Recruiting 57 Thomas Kipps University of California, San Diego Phase 1/2 Recruiting 156 Ed Conner Sangamo BioSciences, Inc. Phase 1/2 Recruiting 6 Edward Kavalerchik Angiocrine Bioscience, Inc. Phase 1 Launching N/A Thomas Kipps University of California, San Diego Phase 1 Active, not recruiting 29 Irving Weissman Stanford University Phase 1 Completed 88 Paul Finnegan Angiocrine Bioscience, Inc. Phase 1 Launching N/A Michael Pulsipher Children's Hospital of Los Angeles Phase 1/2 Launching N/A Anthony Gringeri ImmunoCellular Therapeutics Phase 3 Suspended 414 Christine Brown City of Hope, Beckman Research Institute Phase 1 Recruiting 92 Mark Chao Forty Seven Inc. Phase 1/2 Recruiting 112 Linda Marban Capricor, Inc Phase 2 Completed 25 Rachel Smith Capricor, Inc Phase 2 Active, not recruiting 134 Mehrdad Abedi University of California, Davis Phase 1/2 Recruiting 18 Geoff Symonds Calimmune, Inc. Phase 1/2 Completed 12 John Zaia City of Hope, Beckman Research Institute Phase 1 Active, not recruiting 12 Vicki Wheelock University of California, Davis Phase 1/2 Completed 29 Everett Meyer Stanford University Phase 1 Launching N/A Jeffrey Lawson Humacyte, Inc. Phase 3 Active, not recruiting 355 Samuel Strober Stanford University Phase 1 Active, not recruiting 15 Jeffrey Lawson Humacyte, Inc. Phase 3 Recruiting 240 Scott Batty Medeor Therapeutics, Inc. Phase 3 Recruiting 75

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Biology4Kids.com: Animal Systems: Immune System

March 12th, 2019 3:54 pm

You know when your immune system is at work because of the symptoms you might have. Fever, swelling, and a runny nose are all examples of symptoms during an immunological response. Your immune system can respond many ways to a problem. There would be one response to a knife wound, a separate response to hay fever and pollen, and a specific response to catching a cold.

It may surprise you, but one of the most important parts of the immune system is the entire integumentary system (your skin). Your skin is usually the first defense your body has against disease. It just makes sense. There is far more chance you will get dangerous bacteria or viruses on your skin and hands than breathe those microorganisms in your lungs. You have cells and compounds on your skin that help to kill any bacteria that appear. Always remember to wash your hands; most of the microorganisms that get you sick are picked up when you touch things.

There are also genetic problems with immune systems. Something as simple as an allergic reaction happens because an individual cannot properly tolerate certain allergens. Inflammation and hay fever occur. Normal individuals can destroy those allergens, but people who are "allergic" cannot defend themselves. You could have allergies to animals, food, or plants. Some allergic reactions are so extreme they can kill.

Science Behind the News: Allergies (US-NSF Video)

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The McGowan Institute for Regenerative Medicine | UPMC

March 12th, 2019 3:54 pm

Merging Science with Technology to Treat Disease

Regenerative medicine uses clinical procedures to repair or replace damaged or diseased tissues and organs, versus some traditional therapies that just treat symptoms.

To realize the vast potential of tissue engineering and other techniques aimed at repairing damaged or diseased tissues and organs, the University of Pittsburgh School of Medicine and UPMCestablished the McGowan Institute for Regenerative Medicine. The McGowan Institute serves as a single base of operations for the Universitys leading scientists and clinical faculty working to develop tissue engineering, cellular therapies, and artificial and biohybrid organ devices.

The McGowan Institute is the most ambitious regenerative program in the nation, coupling biology, clinical science, and engineering. Success in our mission will impact patients lives, bring economic benefit, serve to train the next generation of researchers, and advance the expertise of our faculty in the basic sciences, engineering, and clinical sciences. Our efforts proudly build upon the pioneering achievements of the Thomas E. Starzl Transplantation Institute.

While there are certain select therapies based on regenerative medicine principles now in clinical use, much work lies ahead to realize the potential of this growing field. Advances in the underlying science, engineering strategies to harness this science, and successful commercial activities are all required to bring new therapies to patients.

The McGowan Institute sponsors a podcast series on regenerative medicine. Listen to some of the world's leading regenerative medicine researchers and physicians talk about their work.

Listen to the most recent podcasts.

Longevity Protein Rejuvenates Muscle Healing in Old Mice

One of the downsides to getting older is that skeletal muscle loses its ability to heal after injury. New research from the University of Pittsburgh implicates the so-called longevity protein Klotho, both as culprit and therapeutic target.

First Results from Retinal Implant Clinical Trial Presented by UPMC Ophthalmology Expert

Promising first results from the clinical feasibility trial of PRIMA, a wireless retinal implant designed to help restore useful vision in patients with advanced atrophic dry age-related macular degeneration (AMD), were presented recently at the American Academy of Ophthalmology 2018 annual meeting held in Chicago. The presentation was acknowledged as the Best Paper of Retina Session II at the meeting.

Statins May Help Prevent Breast Cancer Metastasis

Mary Kekatos Health Reporter for the Dailymail.com and the Dailymail.com Reporter, recently detailed in her article that statins could prevent the spread of breast cancer, per a new study. Researchers say the drugs, which combat high cholesterol, do not prevent the cancer from occurring but stop it from spreading to other organs. Experiments performed in human cells and laboratory mice found that the pills prevent tumors from migrating to the lungs and liver.

Weighing In: Three Years Post-Op Bariatric Surgery Patients See Big Benefits

For millions of Americans struggling with obesity and considering surgical procedures to achieve weight loss and alleviate obesity-related health complications, a new study adds weight to the health benefits attributed to bariatric surgery.

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What is Genetic Engineering and Pros and Cons of …

March 12th, 2019 3:51 pm

Genetic engineering refers to the set of technologies that directly manipulate on an organisms genes, change the genetic make up of cells and add one or more new traits that are not found in that organism. At the heart of all life is what we call DNA. It is responsible for the abundance of life on this Earth and the reason why we are the way we are. The genetic make-up of any organism is defined by DNA. In nature, the genetic nature never remains fixed.

Genetic engineering has a huge array of applications, for instance, surgery, animal husbandry, medicine, and agriculture. With genetic engineering, many crops species have developed immunity to most lethal diseases. Genetic engineering has also helped to increase yields at the farm. Today, wide-ranging crop species like wheat are genetically modified to achieve high nutritive value, and faster and higher productivity. These days, more and more countries are embracing genetically engineered crops to fight scarcity of food, offer highly nutritious foods, and grow and cultivate crops that are immune to various diseases and pests. Genetic engineering, in many ways, has heralded an age of agricultural revolution, which many hope will help wipe out malnutrition and starvation.

What is genetic engineering? Well, its when a gene of a particular organism is harnessed and the copy inserted into the DNA of another organism to modify its characteristics. An organism is any living thing such as humans, plants, and animals. To understand how genetic engineering works, it would be prudent to know how DNA works. Any organism has a cell. In the cell, there is DNA, which acts as an instructional manual for the entire body.

DNA is responsible for every characteristic of an organism, for example, in humans; its responsible for eye color, hair color, height and so on. So, to harvest the height gene from an organism, biologists use restriction enzyme (which resemble a scissor) to cut it out. The harvested height gene is then inserted into a second targeted organism. The targeted organism then reproduces, and the result is multiplication of organisms with the modified height. The same process applies to genetically modified foods.

Genes rarely ever comprise of a single genetic material. The more complex an organism becomes, the more genetic material it has. Much of it has no use and only a small fraction of it is responsible for our specific characteristics. For example, humans and apes share some 99% of their DNA. It is the rest 1% which can be used to create such spectacular differences.

It is also the amount from which active genetic material is extracted and introduced to a new host cell, usually bacteria. This allows it to perform or inherit a certain function from the new genetic material. If it sounds too tough to understand genetic engineering, just imagine that artificial insulin for diabetics is produced through this method.

The applications of this field are growing each day. One example is the production of insulin for diabetes patients. The field of medicine is reaping the benefits of genetic engineering. They have used the process to create vaccines and human growth hormones, changing the lives of many in the process. Gene therapy has been developed, which could possibly provide a cure for those who suffer from genetic illnesses.

It has also found a place of importance in research. As scientists successfully understand genetic engineering, they use it to resolve issues in current research methods. Most of these are done with the help of genetically modified organisms.

Statistics according to scientists at the Germanys University of Gttingen indicate that Genetically Modified Foods (GMO) increase crop yield by more than 22%. This is why most areas experiencing food shortage have taken up the use of GMOs to help reverse the trend.

Genetic modification greatly increases flavor of crops. For, instance, modification makes corn sweeter and pepper spicier. In fact, genetic modification has the capability to make difficult flavor a lot palatable.

Resistance to disease was the main reason for genetic engineering research. Genetically modified foods exhibit great resistance to various diseases. Just like vaccine, genetic codes are implanted into foods to fortify their immune system.

Genetic modification has enabled researchers to incorporate variety of nutrients like proteins, vitamins, carbohydrates and minerals in crops to accord consumers greater nutritive value. This aspect has helped many in the developing world who cannot afford a balanced diet every single day. In addition, genetic modification has gone a long way towards solving worldwide malnutrition. For instance, rice thats strengthened with vitamin A, referred to as golden rice, now assist in mitigating deficiency of vitamin A across the globe.

Statistically, GMOs have a much longer lifespan than other traditional foods. This means they can be transported to far destinations that lack nutritious foods without fear of going bad.

The use of molecular biology in vaccine creation has bore fruits so far according to FAO (Food and Agriculture Organization of the United Nations). Biologists have been able to genetically engineer plants to generate vaccines, proteins, and other important pharmaceutical products via a technique referred to as pharming.

Production of genetically modified foods involves less time, land, machinery and chemicals. This means you wont worry about greenhouse gas emission, soil erosion or environmental pollution. In addition, with increased productivity witnessed with genetically modified foods, farmers will use less farmland to grow crops. Not to mention, they are already growing foods like corn, cotton, and potatoes without using insecticides because genetically modified foods generate their own insecticides.

Scientists indulge in crop modification to achieve enhanced resistance to diseases and superior crop health. Genetically modified foods also have the capability to resist harsh weather conditions. All these factors lead to one thing: reduced risk of crop failure.

A research study by Brown University concluded that genetic modification normally blends proteins that are not naturally present in the organism, which can result in allergy reactions to certain groups people. In fact, some studies found out that GMOs had caused significant allergic reactions to the population. A separate research by the National Center for Health Statistics reported that food allergies in individuals under 18 years leaped from 3.4% in the year 1997-2999 to 5.1% in 2009-2011.

Although reports have pronounced that genetically modified foods have no impact on the environment, there are some noted environmental impacts. It has been established that GMOs grown in environments that do not favor them often lead to environmental damage. This is evident in the GMO cross-breeding whereby weeds that are cross-bred with modified plants are reported to develop resistance to herbicides. This, eventually, calls for added modification efforts.

The fact that GMOs take the same amount of time to mature, and same effort to cultivate and grow, they dont add any economic gain compared to traditional growing methods.

According to a research study by Food and Agriculture Organization (FAO), GMOs can transfer genes to other members of similar species or different species through a process called gene escape. This gene interaction might take place at different levels including plant, cell, gene or ecosystem. Trouble could arise if, for instance, herbicide resistant genes find way into weeds.

Research finding according to Iowa State University stipulates that some GMOs contain antibiotic characteristics that boost your immunity. However, when consumed, their effectiveness dramatically reduces compared to the real antibiotics.

1. Identification of an organism that exhibits the desired trait or gene of interest.

2. Extracting the DNA from that organism.

3. Through a process called gene cloning, one desired gene (recipe) must be located and copied from thousands of genes that were extracted.

4. The gene is slightly modified to work in a more desirable way once it is inserted inside the recipient organism.

5. The transformation process occurs when new gene(s), called a transgene is delivered into cells of the recipient organism. The most common transformation technique uses a bacteria that naturally genetically engineer plants with its own DNA. The transgene is inserted into the bacteria, which then delivers it into cells of the organism being engineered.

6. The characteristics of the final product is improved through the process called traditional breeding.

Hawaii is well documented as a place where genetically modified papaya trees have been cultivated and grown since 1999. The harvested papayas are disseminated to markets such as the United States and Canada. The reason for modifying these papayas is the Papaya Ringspot virus that has caused havoc for many years. Also, Hawaii papayas have been modified to slow down their maturity to accord suppliers sufficient time to ship to the market.

Statistically, over 90% of soybeans available in the marketplace today are genetically engineered to naturally resist a herbicide known as Round Up. This enhanced resistance enables farmers to use a lot more Round Up to exterminate weeds.

Eggplant, also known as Zucchini, is another food product that is widely genetically modified. Genetically modified eggplant encompasses a protein, which gives it more resistance to insects.

Cotton is very susceptible to diseases, insects, and pests. It is heavily modified to boost yields and resistance to pests and diseases.

Corn also makes the list of the most genetically modified foods. Half of farmers in the United States grow corn that has been genetically modified. Most of the corn is utilized for human consumption and animal feed.

Sugar beets are surprisingly modified due to their high demand in countries like U.S., Canada, and Europe. Genetically modified sugar beets debuted in the United States markets in 2009. They are genetically modified to develop resistance to Round Up.

These days, dairy cows are increasingly being genetically modified with growth hormones to enable faster growth and beef up of yields.

Harnessed from rapeseed oil. According to studies, it is the most well know genetically modified oil in the world.

Most countries require that any genetically modified food be labeled. 64 countries across the world with an estimated world population of 64% already label GMOs, the entire European Union included. China also joined the bandwagon of labeling GMOs. Although genetically modified food companies are fighting against labeling, the battle may not be won in the near future.

Science has been able to genetically engineer animals and plants alike. While the animals are used in research or sold as a novelty pet item, the plants have a different purpose. Following the years of pesticide and insecticide use, most pests have developed an immunity to them. With the help of scientists that understand genetic engineering, farmers now benefit from seeds that have been engineered.

They are provided with traits from other plants that can naturally balance the plant-pest relationship. As expected, the use of such engineering has become heavily commercialized and is used to produce more attractive varieties of food.

Genetically modified food is not an experimental project. Foods that have been engineered to look, smell and taste better have found their place in the supermarket shelves since 1994. Thats twenty years ago and the trend has become habit. Apart from their looks, foods are produced simply for consumer convenience, such as seedless fruits.

As of now, soybean, cotton seed oil, corn and canola are the most advanced of the modified crops. Most of the livestock grown in the country is feed with crops that were genetically modified, making them partly genetically modified organisms in the long run. For those that understand genetic engineering, the growing use of the technology is quite alarming.

However, not all is wonderful in world of genetic engineering. It has been launched into controversy many times over the last decade. Since it is still a fledgling technology whose implications are yet not clear, there are many liberties taken with it. Lack of policy and laws makes it easy for research based companies to misuse the work of those that understand genetic engineering.

Most concerns regarding genetically modified food and animals are the ethical ramifications, while others are related to problems in the ecology and future misuse of the technology. As a result, the process and technology is highly regulated as of now.

Even with the regulations and laws being passed to reign in the rampant abuse of genetic engineering, the process is not in a hurry to stop. The government is pushing for one step at a time, such as labeling foods as GM Foods in markets to help the customers make their own choice. But the commercial advantages are quite high and further research will be able to possibly solve many of our health and poverty related issues. This is the biggest argument in the favor of engineering. Even so, it takes a lot many years to fully understand genetic engineering.

A true environmentalist by heart . Founded Conserve Energy Future with the sole motto of providing helpful information related to our rapidly depleting environment. Unless you strongly believe in Elon Musks idea of making Mars as another habitable planet, do remember that there really is no 'Planet B' in this whole universe.

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Stem Cell Dental Implants Grow New Teeth In 2 Months …

March 12th, 2019 2:48 am

Dentures and implants may now be a thing of the past because scientists have the ability to grow new teeth in a patients mouth.

This is huge for the many adults who end up losing a tooth or multiple teeth during their lifetimes.

As of now, the only options for a missing tooth include implants, or if all teeth are missing, dentures. However, these two methods cause serious dental health problems.

Health issues associated with dental implants include infection at the implant site, injury or damage to the surrounding structures, nerve damage, and sinus problems. Despite being the preferred treatment for missing teeth today, dental implants can fail and have no ability to remodel with surrounding jaw bone, which undergoes necessary and inevitable changes throughout a persons life. (Dentistry iQ)

Dentures can be uncomfortable and make eating difficult. Also, they can cause gum and mouth irritation or infections.

By growing a new tooth in the location where one lost a tooth, all issues associated with implants or dentures are gone. This is a much-needed medical advancement, especially considering that by age 7426% of adults have lost all of their permanent teeth. (Underground Health Reporter)

A new technique pioneered at the Tissue Engineering, and Regenerative Medicine Laboratory of Dr. Jeremy Mao, Edward V. Zegarelli Professor of Dental Medicine, and a professor of biomedical engineering at Columbia University can orchestrate the bodys stem cells to migrate to three-dimensional scaffold that is infused with the growth factor. This can yield an anatomically correct tooth in as soon as nine weeks once implanted in the mouth. (Dentistry iQ)

That is right. Scientists can help the body grow a new tooth in about two months. Gone will be the days of dentures and painful tooth implants.

Key consideration in tooth regeneration is finding a cost-effective approach that can translate into therapies for patients who cannot afford or who are not suitable candidates for dental implants, Dr. Mao said. Cell-homing-based tooth regeneration may provide a distinct pathway toward clinical translation.

In other words, it is may be a less expensive process. However, one thing that is known for sure is that it is far less invasive.

Dental implants usually consist of a cone-shaped titanium screw with a roughened or smooth surface and are placed in the jaw bone. While implant surgery may be performed as outpatient procedure, healing times vary widely, and successful implantation is a result of multiple visits to certified clinicians, including general dentists, oral surgeons, prosthodontists, and periodontists. (Dentistry iQ)

It might just be me, but the thought of a titanium screw anywhere near my mouth gives me the chills.

One more thing, you dont have to wait to get a stem cell treatment with your own stem cells! Stem cells can still help your teeth without a direct stem dental implant. Click HERE to find out how you can receive a stem cell treatment by multiplying your own stem cells.

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Regenerative Medicine in Patient Care – Center for …

March 12th, 2019 2:45 am

Regenerative medicine-based services are available to patients, including a consult service and one of the country's largest transplant centers.

Patients at Mayo Clinic are becoming increasingly interested in whether there are any regenerative medicine applications suitable for their conditions. To meet this interest, the Regenerative Medicine Consult Service was launched within the Mayo Clinic William J. von Liebig Center for Transplantation and Clinical Regeneration in 2011.

Teams composed of bone specialists, biologists and engineers at Mayo Clinic are investigating the potential of simple hip decompression, a new regenerative technique, for patients with early-stage osteonecrosis of the hip.

Transplant medicine laid much of the groundwork for the field of regenerative medicine. Today, transplantation (replacement) is one of the three approaches being studied and applied by the Center for Regenerative Medicine to restore tissue and organ function.

Mayo Clinic has the largest and most experienced transplant practice in the United States. In total, Mayo's campuses in Arizona, Florida and Minnesota perform more than 1,500 solid organ and bone marrow transplants each year. Staff members skilled in more than a dozen specialties work together to ensure quality care and successful recovery.

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Stem Cell Therapy Training Course & Procedure Kits by Apex

March 10th, 2019 10:54 pm

Stem Cell Therapy Training Course & Procedure Kits by Apex

Stem cell therapy has some of the most exciting treatment potential in medicine today. Stem cells are the bodys master cells. They are undifferentiated cells which allow them to develop into other types of cells that are required to repair or replace damaged tissue. Stem cells can stimulate the formation of cartilage, tendon, ligaments, bone and fibrous connective tissues. Stem cells have been clinically and scientifically proven to effectively treat most chronic pain conditions, accelerate the healing, and reduce scarring.

A high volume of stem cells is obtained from the patients own bone marrow or fat tissue (adipose). Once the stem cells have been concentrated, they are injected into damaged areas of the body to promote regeneration and healing. These therapies are a safe, nonsurgical treatment option for most chronic pain conditions, wound care, and aesthetic abnormalities.

Not all stem cell therapy procedures or concentrating processes are the same. APEX Biologixs Stem Cell Concentration System offers the best processing technique to maximize patient outcomes. The APEX Biologix system creates a highly concentrated injectate of stem cells and growth factors.

With our system, we provide training videos, processing guides, and remote training if needed.

Regenerative medicine is a rapidly growing specialty, and with popular demand, more physicians are seeking a didactic learning environment where they can learn the science and practice performing these therapies.

APEX Biologix partners with the Advanced Regenerative Medicine Institute (ARMI) to host training seminars where highly qualified physicians and specialists in regenerative medicine provide the essential instruction and necessary hands-on training. The goal of these training courses is to educate physicians interested in regenerative medicine and help them implement these cutting-edge therapies into their practice.

APEX Biologix provides complimentary business and marketing support to physicians who want to begin offering regenerative therapies to their patients. APEX Biologix has helped several clinics nationwide implement these therapies into their practices. Some of these therapies have become the clinics highest revenue stream.

Learn about regenerative medicine and how to successfully incorporate regenerative medicine into your practice.

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Stem Cell Therapy for Back Pain Regenerative Injections …

March 10th, 2019 10:54 pm

Your spine is a complex network of bones, tendons, ligaments, muscles, soft tissue, cartilage and nerves. So many things can go wrong with your back. But stem cell therapy for lumbar discs, herniated disc stem cell therapy and stem cell therapy for bulging discs can ease your pain and repair the damage. Additionally, you can get an injection of stem cells for disc regeneration.

If youre living a nightmare of everyday back pain, it may be time for regenerative medicine. Traditional treatments offer a limited number of options, ranging from medication to surgery.

While you can cover the pain and mask the symptoms with medications and injections or even undergo surgery and extensive rehab there are no guarantees that your pain will end. In many cases, pain management just becomes a part of your life. Stem cells for disc regeneration is fast becoming the go-to procedure if youve whove suffered from back injuries or chronic back pain.

A safe and proactive alternative to invasive procedures and narcotics is herniated disc stem cell therapy and other stem cell procedures that target back pain. Stem cell technology is changing the way people view chronic pain. Instead of having to cut or fuse your spine, your very own stem cells can be used to treat the source of your pan directly.

The process often can be done in as little as an hour or two in your local New York pain management doctors office. Dr. Leon Reyfman and his team have seen positive results with stem cells for disc regeneration. Theres no more reason to mask symptoms when stem cells and platelet rich plasma treatments are able to rebuild damaged or diseased discs in your spine.

Degenerative disc disease is the term commonly used when speaking about the effects of aging on your spine. As you age, the spinal discs that act as shock absorbing cushions between your vertebrae tend to break down or rupture altogether. These discs allow your spine to bend, twist and flex. As the discs become compromised, your range of motion is greatly affected and you experience varying amounts of pain.

Degenerative disc disease typically impacts discs of your neck (your cervical spine) or the discs of your lower back (your lumbar spine). If youre among the many people suffering with chronic pain in your lower back, theres a good chance youre experiencing some internal disruption of your lumbar discs. Degenerative disc disease in your lumbar region can potentially lead to far worse problems than simply back pain. Some of the resulting conditions are:

All of these conditions can put a lot of pressure on your spinal cord and spinal nerves, which compromises your nerve function and causes you pain. Stem cell therapy for lumbar discs has proven to be particularly effective at repairing degenerated discs. These minimally invasive injections are far superior to other therapies previously available for lumbar pain.

Stem cell therapy for bulging disc and injecting stem cells for herniated disc problems are growing in popularity. And while bulging and herniated discs are related to degenerative disc disease, they arent the same thing:

Since the difference between a bulging disc and a herniated disc is just a matter of degree, getting stem cells for herniated discs and bulging discs work in exactly the same fashion. Herniated disc stem cell therapy uses stem cells from your bone marrow and platelet rich plasma from your own blood. Both are safe, effective ways to treat damaged discs because they simply turbo-charge your bodys ability to heal itself.

Dont be discouraged if your discs arent the source of your back pain. Stem cell therapy is also being used to treat several other types of spinal conditions, including:

Back pain can be tricky. Even if youve been diagnosed with a bulging or herniated disc, your pain may actually be the result of problems with your spinal ligaments. This basically means youve sprained your back. Ligament instability is also treatable with stem cells and platelet rich plasma. Since the regenerative procedures rely on your own cells, theres little-to-no risk of rejection, and you can begin to feel relief very soon after a treatment.

Since stem cell therapy promotes your bodys natural healing, its not a quick fix. It takes time for you to heal enough to feel the difference the treatments are making. It could take two to three weeks after the injection to begin to notice results. The swelling in your spine could take a couple months to go down entirely. But you will feel significantly better by then.

For a lot of patients, a single round of stem cell therapy for lumbar discs or cervical discs is all thats needed to drastically reduce their back pain. Plus, you can expect these results to improve for the rest of your life. If youre suffering from a particularly aggressive degenerative condition, however, additional stem cell injections may be necessary.

While the future of using stem cell therapy for disc regeneration is exciting, non-surgical stem cell technology has been in practice since the 1990s. The science and methods have improved considerably. Now the entire procedure has been reduced to a matter of hours.

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Does Stem Cell Therapy Work? – Sports-health | Trusted …

March 10th, 2019 10:54 pm

Medical professionals debate whether or not stem cells therapy is an effective treatment for sports injuries, such as ACL tears and chronic tendonitis. It is a controversial subject and research is ongoing.

See Anterior Cruciate Ligament (ACL) Tears

The theories behind stem cell therapyResearchers theorize that when applied to a sports injury, stem cells might:

See Knee Cartilage Repair, Regeneration, and Replacement

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Future research will help show if none, all, or a combination of these processes is at work. In the meantime, doctors debate whether or not stem cells are a good treatment option for sports injuries.

The challenge facing researchersThere is no standard recipe for stem cell therapy. The stem cell therapy in one study is not necessarily the same as the stem cell therapy in another study. The differences can include:

Because of these differences, it is difficult for researchers to draw conclusions or make generalizations based on existing studies.

Many sports medicine doctors use stem cell therapy in combination with another regenerative medicine therapy, platelet rich plasma (PRP). These physicians believe that PRP can make the most of the stem cells potential effects.1,2

See Types of Regenerative Medicine for Sports Injuries

PRP is derived from a sample of the patients blood. In the bloodstream, platelets secrete substances called growth factors and other proteins that:

See Are PRP Injections Effective?

PRP can be used alone to treat sports injuries, such as elbow tendinopathy.

See What Is the Difference Between Tendonitis, Tendinosis, and Tendinopathy?

Like stem cell therapy, PRP therapy is a not a standard therapy and may not be covered by insurance.

See Pros and Cons of Using PRP for Tendon Injuries

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