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Chinook Therapeutics to Present at SVB Securities Global Biopharma Conference

February 8th, 2023 12:03 am

SEATTLE, Feb. 07, 2023 (GLOBE NEWSWIRE) -- Chinook Therapeutics, Inc. (Nasdaq: KDNY), a biopharmaceutical company focused on the discovery, development and commercialization of precision medicines for kidney diseases, today announced that Chinook management is scheduled to participate in a virtual fireside chat at the SVB Securities Global Biopharma Conference on Tuesday, February 14, 2023 at 11:20 am ET, as well as 1x1 meetings.

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Vaxcyte to Present at the SVB Securities Global Biopharma Conference

February 8th, 2023 12:03 am

SAN CARLOS, Calif., Feb. 07, 2023 (GLOBE NEWSWIRE) -- Vaxcyte, Inc. (Nasdaq: PCVX), a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, today announced that Company management will participate in a fireside chat at the SVB Securities Global Biopharma Conference on Tuesday, February 14, 2023, at 3:00 p.m. ET / 12:00 p.m. PT.

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Larimar Therapeutics Appoints Dr. Gopi Shankar as Chief Development Officer

February 8th, 2023 12:03 am

BALA CYNWYD, Pa., Feb. 07, 2023 (GLOBE NEWSWIRE) -- Larimar Therapeutics, Inc. (“Larimar”) (Nasdaq: LRMR), a clinical-stage biotechnology company focused on developing treatments for complex rare diseases, today announced the appointment of Gopi Shankar, PhD, MBA, FAAPS, to the newly created position of Chief Development Officer (CDO). Dr. Shankar will report directly to Chief Executive Officer Carole Ben-Maimon, MD, and will be responsible for the strategic development of the Company’s clinical and R&D programs, including additional applications of the Company’s platform technology.

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Viracta Therapeutics to Present at the 2023 SVB Securities Global Biopharma Conference

February 8th, 2023 12:03 am

SAN DIEGO, Feb. 07, 2023 (GLOBE NEWSWIRE) -- Viracta Therapeutics, Inc. (Nasdaq: VIRX), a precision oncology company focused on the treatment and prevention of virus-associated cancers that impact patients worldwide, today announced that Mark Rothera, its President and Chief Executive Officer, is scheduled to present at the virtual 2023 SVB Securities Global Biopharma Conference on Tuesday, February 14, 2023, at 1:00 p.m. ET.

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Lifecore Biomedical Announces Sale of Curation Foods’ Avocado Products Business

February 8th, 2023 12:03 am

Proceeds to be used for debt paydown Proceeds to be used for debt paydown

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Tenaya Therapeutics to Participate in Upcoming Investor Conferences

February 8th, 2023 12:03 am

SOUTH SAN FRANCISCO, Calif., Feb. 07, 2023 (GLOBE NEWSWIRE) -- Tenaya Therapeutics, Inc. (NASDAQ: TNYA), a clinical-stage biotechnology company with a mission to discover, develop and deliver potentially curative therapies that address the underlying causes of heart disease, today announced that company management will participate in the SVB Securities Global Biopharma Conference and Cowen’s 43rd Annual Health Care Conference. Details of participation are as follows:

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Cellectis Announces Closing of Global Offering and Exercise of Underwriters’ Option to Purchase Additional Shares

February 8th, 2023 12:03 am

NEW YORK, Feb. 07, 2023 (GLOBE NEWSWIRE) -- Cellectis S.A. (“Cellectis” or the “Company”) (Euronext Growth: ALCLS - NASDAQ: CLLS), a clinical-stage biotechnology company using its pioneering gene-editing platform to develop life-saving cell and gene therapies, announced today:

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ASKA Pharmaceutical : February 7 2023 EME and ASKA Announce Collaboration Agreement on Creating Novel PharmaLogical VHH to address an unmet medical…

February 8th, 2023 12:02 am

ASKA Pharmaceutical : February 7 2023 EME and ASKA Announce Collaboration Agreement on Creating Novel PharmaLogical VHH to address an unmet medical need in Obstetrics and Gynecology  Marketscreener.com

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Stem Cell Therapy Is It Right for You? Cleveland Clinic

January 31st, 2023 12:04 am

Few of us know what they are or exactly how they work. But many of us have heard about the healing powers of stem cells, as well as the controversy surrounding them. Stem cells are well-debated and highly complex with promises ranging from fixing damaged knees to regenerating receding hairlines.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.Policy

But what are stem cells? And, whats all the fuss all about?

Director of the Center for Regenerative Medicine and Surgery, Amy Lightner, MD, shares the differences between stem cell types, how stem cells can be used and when to be cautious of claims that might be too good to be true.

When most of us think of stem cells, we probably recall images of Dolly the cloned sheep. While its true that Dolly was born of stem cells, her place in science history is just one of many advancements in the field.

In fact, there are many different types of stem cells, each of which has different responsibilities and abilities. What unifies them is their ability to regenerate into new cells.

Regenerative medicine is an emerging field that uses innovative treatments to help regenerate or heal cell function thats lost due to aging, disease or injury, Dr. Lightner explains. The way we achieve this is by using stem cells in large quantities, targeted to a certain area, that the body uses to promote healing.

Adult stem cells are the only type of stem cells that are currently approved for medical use in the United States by the U.S. Food and Drug Administration (FDA). The term adult stem cells is a little confusing because theyre actually found in infants, children and adults. These cells live in a variety of tissue in our bodies including bone marrow, muscles, your brain, your intestines and more.

Think of adult stem cells as a little army of cells that can regenerate themselves into new cells to maintain and repair the tissue or muscle where theyre found. The catch with adult stem cells is that they cant become different types of cells (for example, blood stem cells can only become new blood cells, not skin or brain cells).

Unlike adult stem cells, embryonic stem cells have many more possibilities. Harvested during an embryos blastocyst stage (about five or six days after an embryo has been fertilized in a lab), embryonic stem cells have the potential to become any type of cell (called pluripotent cells). For these reasons, embryonic stem cells are the type of stem cells that generate the controversy most people associate with the topic.

Stem cell therapy has been around since the 1970s, when the first adult bone marrow cells were used to treat blood disease. A bone marrow transplant allows a recipient whose bone marrow cells have been damaged by chemotherapy or disease to receive healthy bone marrow stem cells from a donor.

Those stem cells have the potential to mature within the blood system into different immune cells that recognize and fight off different types of blood cancer. And they also have the ability to heal, says Betty Hamilton, MD, Department of Hematology and Medical Oncology.

Bone marrow transplants are currently used to treat diseases including:

While you may have heard about the use of stem cell therapy for knees, back pain, arthritis, hair loss, diabetes and more, no other types of stem cell therapy beyond bone marrow transplants have yet been approved by the FDA. But thousands of clinical trials are available ranging from treatments for Crohns disease to multiple sclerosis and more. The common link between all these trials is the ability of the stem cells to reduce inflammation and repair damage to your body.

Dr. Hamilton and Dr. Lightner agree that were only just beginning to scratch the surface of stem cell therapy. In recent years, during the height of the COVID-19 pandemic, many clinical trials were underway to explore whether stem cells could be used to help treat the damaged lungs in people severely affected by the disease.

I think potential is the perfect word to describe stem cells, says Dr. Hamilton. We know they have these anti-inflammatory and regenerative properties where they can provide a significant improvement to someone dealing with a certain disease. There are so many diseases where inflammation happens, and something needs to be repaired, and so any help the immune system can get provides a lot of potential.

Scientists are also researching whether adult stem cells can turn into pluripotent stem cells, which would allow the cells to change into any cell type without involving the use of embryonic stem cells.

While the potential for stem cell therapy is great, doctors caution that were not quite there yet.

I always tell patients that ask about stem cell therapy clinics or traveling overseas for stem cell therapy treatment that if its not something that is a clinical trial with FDA oversight, then they have no real way of knowing whats being given to them, advises Dr. Lightner.

This means more harm can come than good if you dont know exactly whats being given to you. Or, in some cases, youre just spending thousands of dollars for what ends up being saline, Dr. Lightner says.

The best way to know that youre receiving sound medical treatment is to make sure the one youre considering is approved by the FDA on its Clinical Trials database.

Dr. Lightner cautions against treatments that sound too good to be true. While stem cell therapy has helped improve and save millions of lives, its best to know what exactly youre signing up for by seeking out a qualified medical provider offering an FDA-approved clinical trial.

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Stem Cell Therapy | Mellon Center Approach | Cleveland Clinic

January 31st, 2023 12:04 am

Q: What are the types of stem cell therapy?

A: Stem cells are primitive cells that are capable of self-renewal (i.e., to divide to replenish their population); are pluripotent (i.e., able to differentiate into different mature cells); and are able to create, maintain, or repair tissues. There are several general categories of stem cells, including:

Two general stem-cell-based therapeutic strategies have been considered in MS:1

This document addresses AHSCT and MSC transplantation separately.

A: AHSCT is a multi-step procedure, which includes:

Mobilization typically is performed as an outpatient. Conditioning, PBHSC infusion, and initial recovery usually are performed during an approximately 1-month hospitalization in a specialized transplant unit.

A: A sizable number of case series, uncontrolled phase 2 clinical trials, and randomized clinical trials have demonstrated, in aggregate, potent efficacy of AHSCT in patients with active relapsing MS, including marked reduction in relapses, MRI lesion activity, and brain volume loss (after initial acceleration).1-3 In two analyses, the rate of no evidence of disease activity at 2 years was 70-90% in AHSCT case series and trials compared to 15-50% in clinical trials of MS disease modifying therapies (DMTs).4,5 A sizable proportion of patients treated with AHSCT demonstrate improvement in disability, for example, 64% at 4 years in a recent case series.6 Disease control often is durable, lasting up to 15 years or more without the need for ongoing disease modifying therapy (DMT) in many patients.7 Nonetheless, some patients require resumption of standard DMTs at some point after AHSCT, particularly with lower intensity non-myeloablative conditioning regimens.

The potent efficacy is attributed to immunoablative conditioning that depletes pathogenic immune cells; the durability of benefit is attributed more normal regulatory function and T-cell and B-cell repertoires following immune reconstitution.4

A: Early toxicity is common in patients undergoing AHSCT and potentially includes MS relapse during mobilization and conditioning, complications of leukapheresis, side effects of cytotoxic agents comprising the conditioning regimen (e.g., nausea or infertility), complications of myelosupression (e.g., infection or bleeding complications), and engraftment syndrome after re-infusion of PBHSCs (fever, rash, pulmonary edema, liver or renal impairment, and encephalopathy). Patients typically are hospitalized for approximately 1 month when undergoing conditioning and transplantation, and for initial recovery. Previous estimates of overall transplant-related mortality in MS were 2% or more. The current estimate is 0.2-0.3% for AHSCT performed after 2012.4 The improved safety is due to increased experience with the procedure, refinement of the protocol, and better selection of patients with lower risk of complications.

After recovery, adverse effects are rare and include infection (principally related to herpes zoster) and secondary autoimmune disorders. One potential advantage is that after AHSCT patients typically do not need ongoing MS DMT, with the associated cumulative risk of adverse effects.

A: The estimated cost for uncomplicated AHSCT is approximately $150,000. One potential advantage is that after recovery patients typically do not need ongoing MS DMT, with the associated cumulative cost. Nevertheless, most health insurance plans do not cover AHSCT, so obtaining coverage often is difficult.

A: Patients most likely to benefit from AHSCT are young (approximately 55 years or less), with relatively recent disease onset (approximately 10 years or less), still ambulatory, with highly active MS with recent clinical relapses or MRI lesion activity, and continued disease activity despite treatment with approved DMTs especially high-efficacy DMTs. Both the American Society for Blood and Marrow Transplantation 2 and National MS Society3 have published policy statements that AHSCT is a reasonable option in such patients, who are at high risk for disability.

A: Because of the complexity of the AHSCT procedure and the need for appropriate patient selection and follow-up, AHSCT for MS should be performed by centers with expertise and experience in transplant and that are affiliated with centers with experience and expertise in management of MS.1-3We advise patient not to undergo AHSCT in free-standing transplant clinics, especially in the absence of a detailed plan for follow-up and management of medical and neurologic issues post-transplant.

A: Because of the uncertain efficacy and safety of AHSCT compared to approved DMTs for MS, the Mellen Center is participating in the ongoing Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) clinical trial sponsored by the National Institute of Allergy and Infectious Diseases and the Immune Tolerance Network (ClinicalTrials.gov Identifier: NCT04047628). This multicenter, randomized, rater-blinded trial compares the efficacy, safety, cost-effectiveness, and immunologic effects of AHSCT versus high-efficacy DMTs in participants with highly active, treatment-refractory, relapsing MS.

Because of unanswered questions regarding the efficacy of AHSCT in MS and substantial associated risk, our priority is to enroll patients for whom AHSCT is being considered into the BEAT-MS trial. We will consider AHSCT outside of the BEAT-MS trial for selected patients for whom AHSCT appears indicated but who are not eligible to participate in the study.

A: Typically, transplant physicians monitor and manage transplant-related adverse effects for the first 6 months following uncomplicated AHSCT (longer if there are complications). After 6 months following uncomplicated AHSCT, transplant-related adverse effects are rare. Patients need to be monitored primarily for symptoms or other findings suggesting infection or secondary autoimmune disorders. Long-term MS disease monitoring is similar to typical MS, with clinical visits and periodic MRIs.

A: Several analyses demonstrated that AHSCT has modest or no efficacy in preventing or reversing progressive disability worsening in the absence of recent relapses or MRI lesion activity. Conversely, the risk of adverse effects and transplant-related mortality are increased in progressive MS due to greater neurologic disability, older age, and increased likelihood of comorbidities. Many of the transplant-related deaths in recent series were patients with progressive MS.4 As a result, AHSCT generally is not advised for patients with non-active progressive MS and/or severe disability.

A: A recent publication reported potent efficacy of non-myeloablative AHSCT in preventing relapses, improving disability, and improving quality of life in 11 patients with aquaporin-4-positive neuromyelitis optica spectrum disorders (NMOSD).8 There now are 3 medications with regulatory approval to treat NMOSD plus several other medications used off-label. The findings from this small uncontrolled case series suggests AHSCT might be an option for patients with NMOSD who do not achieve adequate disease control from the available medication options. Rigorous formal clinical trials are needed to more definitively assess the efficacy and safety of AHSCT in NMOSD. We have not performed AHSCT for NMOSD at Cleveland Clinic.

A: Studies of various stem cell approaches to directly replace myelin-forming cells have been proposed (e.g., transplantation of oligodendrocyte progenitor cells or induced pluripotent stem cells), but none has been completed.1 To date, the most experience is with transplantation of mesenchymal stem cells (MSCs), pluripotent stromal cells present in a perivascular niche in a variety of tissues. In addition to their ability to differentiate into mesodermal lineage derivatives (e.g., bone, cartilage, connective tissue, and adipose tissue), MSCs appear to function to limit inflammatory tissue damage and promote tissue repair, including in the central nervous system, through elaboration of a large number of soluble immunomodulatory and trophic factors. These properties have led to a large number of studies investigating the potential benefit of MSC transplantation to treat a wide variety of inflammatory and tissue injury conditions.1 There also are a large number of commercial stem cell clinics offering MSC transplantation for a wide range of conditions.

A: A sizable number of preliminary trials of MSC transplantation in MS have been reported,1 including one conducted at the Mellen Center.9 These studies had different study populations, cell products, routes of administration, and study protocols, making it difficult to generalize the results. In aggregate, the studies reported good safety and tolerability, and some provided preliminary evidence of benefit. A recent study utilizing cell production procedures intended to augment production of neurotrophic factors by the MSCs and multiple intrathecal administrations, reported more prominent efficacy.10

Despite the sizable number of studies of MSC transplantation, there are a many unanswered technical questions, including the best tissue source (e.g., bone marrow, adipose tissue, or placenta/umbilical cord), whether the cells should be autologous (i.e., from the patient) or allogeneic (i.e., from someone without MS), the optimal cell culture methods to maximize yield and stimulate characteristics that increase therapeutic potency, whether the cells can be cryopreserved (frozen and stored) or need to be harvested directly from culture, dose (i.e., how many MSCs are administered), dosing schedule (i.e., for how long the therapeutic benefit lasts and how often the MSCs need to be administered), and optimal route of administration (i.e., intravenous, intrathecal, or both), among other issues. Because of these unanswered technical questions, MSC transplantation currently is an experimental treatment and should not be performed outside of rigorous formal clinical trials

A: There are a large number of commercial stem cell clinics in the U.S. and other countries offering treatments marketed as stem cells and presumed to be predominantly MSCs, on a fee-for service basis. However, because of the lack of quality control, lack of regulatory oversight, and lack of any validation of their efficacy or safety, we strongly advise patients not to pursue stem cell treatments at commercial stem cell clinics, outside of rigorous formal clinical trials. Many of these operations are potentially fraudulent.

Although MSC transplantation generally has been well-tolerated and safe in formal clinical trials, complications have been reported when administered in commercial stem cell clinics, including among other reports severe loss of vision following intravitreal injection11 and malignant spinal cord neoplasm following intrathecal injection.12

In addition, a number of concerns regarding commercial stem cell clinics have been raised: 13,14

A: Patient who undergo MSC transplantation should be monitored for symptoms or other findings indicating potential complications, including local or systemic infection, ectopic tissue formation, neoplasia, and arachnoiditis (following intrathecal administration). Long-term MS disease monitoring is similar to typical MS, with clinical visits and periodic MRIs.

Last Updated: 10 DEC 2020

Approach last updated: February 14, 2021

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STEM | Description, Development, & Facts | Britannica

January 31st, 2023 12:02 am

STEM, in full science, technology, engineering, and mathematics, field and curriculum centred on education in the disciplines of science, technology, engineering, and mathematics (STEM). The STEM acronym was introduced in 2001 by scientific administrators at the U.S. National Science Foundation (NSF). The organization previously used the acronym SMET when referring to the career fields in those disciplines or a curriculum that integrated knowledge and skills from those fields. In 2001, however, American biologist Judith Ramaley, then assistant director of education and human resources at NSF, rearranged the words to form the STEM acronym. Since then, STEM-focused curriculum has been extended to many countries beyond the United States, with programs developed in places such as Australia, China, France, South Korea, Taiwan, and the United Kingdom.

In the early 2000s in the United States, the disciplines of science, technology, engineering, and mathematics became increasingly integrated following the publication of several key reports. In particular, Rising Above the Gathering Storm (2005), a report of the U.S. National Academies of Science, Engineering, and Medicine, emphasized the links between prosperity, knowledge-intensive jobs dependent on science and technology, and continued innovation to address societal problems. U.S. students were not achieving in the STEM disciplines at the same rate as students in other countries. The report predicted dire consequences if the country could not compete in the global economy as the result of a poorly prepared workforce. Thus, attention was focused on science, mathematics, and technology research; on economic policy; and on education. Those areas were seen as being crucial to maintaining U.S. prosperity.

Findings of international studies such as TIMSS (Trends in International Mathematics and Science Study), a periodic international comparison of mathematics and science knowledge of fourth and eighth graders, and PISA (Programme for International Student Assessment), a triennial assessment of knowledge and skills of 15-year-olds, reinforced concerns in the United States. PISA 2006 results indicated that the United States had a comparatively large proportion of underperforming students and that the country ranked 21st (in a panel of 30 countries) on assessments of scientific competency and knowledge.

The international comparisons fueled discussion of U.S. education and workforce needs. A bipartisan congressional STEM Education Caucus was formed, noting:

Our knowledge-based economy is driven by constant innovation. The foundation of innovation lies in a dynamic, motivated and well-educated workforce equipped with STEM skills.

While the goal in the United States is a prepared STEM workforce, the challenge is in determining the most-strategic expenditure of funds that will result in the greatest impact on the preparation of students to have success in STEM fields. It is necessary, therefore, to determine the shortcomings of traditional programs to ensure that new STEM-focused initiatives are intentionally planned.

A number of studies were conducted to reveal the needs of school systems and guide the development of appropriately targeted solutions. Concerned that there was no standard definition of STEM, the Claude Worthington Benedum Foundation (a philanthropical organization based in southwestern Pennsylvania) commissioned a study to determine whether proposed initiatives aligned with educator needs. The study, which was administered jointly by Carnegie Mellon University (CMU) and the Intermediate Unit 1 (IU1) Center for STEM Education, noted that U.S. educators were unsure of the implications of STEM, particularly when scientific and technological literacy of all students was the goal. Educators lacked in-depth knowledge of STEM careers, and, as a consequence, they were not prepared to guide students to those fields.

The findings from several studies on educational practices encouraged U.S. state governors to seek methods to lead their states toward the goal of graduating every student from high school with essential STEM knowledge and competencies to succeed in postsecondary education and work. Six states received grants from the National Governors Association to pursue three key strategies: (1) to align state K-12 (kindergarten through 12th grade) standards, assessments, and requirements with postsecondary and workforce expectations; (2) to examine and increase each states internal capacity to improve teaching and learning, including the continued development of data systems and new models to increase the quality of the K-12 STEM teaching force; and (3) to identify best practices in STEM education and bring them to scale, including specialized schools, effective curricula, and standards for Career and Technical Education (CTE) that would prepare students for STEM-related occupations.

In southwestern Pennsylvania, researchers drew heavily on the CMU/IU1 study to frame the regions STEM needs. In addition, a definition for STEM was developed in that region that has since become widely used, largely because it clearly links education goals with workforce needs:

[STEM is] an interdisciplinary approach to learning where rigorous academic concepts are coupled with real-world lessons as students apply science, technology, engineering, and mathematics in contexts that make connections between school, community, work, and the global enterprise enabling the development of STEM literacy and with it the ability to compete in the new economy.

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What is STEM Education? | Live Science

January 31st, 2023 12:02 am

STEM education is a teaching approach that combines science, technology, engineering and math. Its recent successor, STEAM, also incorporates the arts, which have the "ability to expand the limits of STEM education and application," according to Stem Education Guide (opens in new tab). STEAM is designed to encourage discussions and problem-solving among students, developing both practical skills and appreciation for collaborations, according to the Institution for Art Integration and STEAM (opens in new tab).

Rather than teach the five disciplines as separate and discrete subjects, STEAM integrates them into a cohesive learning paradigm based on real-world applications.

According to the U.S. Department of Education (opens in new tab) "In an ever-changing, increasingly complex world, it's more important than ever that our nation's youth are prepared to bring knowledge and skills to solve problems, make sense of information, and know how to gather and evaluate evidence to make decisions."

In 2009, the Obama administration announced the "Educate to Innovate (opens in new tab)" campaign to motivate and inspire students to excel in STEAM subjects. This campaign also addresses the inadequate number of teachers skilled to educate in these subjects.

The Department of Education now offers a number of STEM-based programs (opens in new tab), including research programs with a STEAM emphasis, STEAM grant selection programs and general programs that support STEAM education.

In 2020, the U.S. Department of Education awarded $141 million in new grants and $437 million to continue existing STEAM projects a breakdown of grants can be seen in their investment report (opens in new tab).

STEAM education is crucial to meet the needs of a changing world. According to an article from iD Tech (opens in new tab), millions of STEAM jobs remain unfilled in the U.S., therefore efforts to fill this skill gap are of great importance. According to a report from the U.S. Bureau of Labor Statistics (opens in new tab) there is a projected growth of STEAM-related occupations of 10.5% between 2020 and 2030 compared to 7.5% in non-STEAM-related occupations. The median wage in 2020 was also higher in STEAM occupations ($89,780) compared to non-STEAM occupations ($40,020).

Between 2014 and 2024, employment in computer occupations is projected to increase by 12.5 percent between 2014 and 2024, according to a STEAM occupation report (opens in new tab). With projected increases in STEAM-related occupations, there needs to be an equal increase in STEAM education efforts to encourage students into these fields otherwise the skill gap will continue to grow.

STEAM jobs do not all require higher education or even a college degree. Less than half of entry-level STEAM jobs require a bachelor's degree or higher, according to skills gap website Burning Glass Technologies (opens in new tab). However, a four-year degree is incredibly helpful with salary the average advertised starting salary for entry-level STEAM jobs with a bachelor's requirement was 26 percent higher than jobs in the non-STEAM fields.. For every job posting for a bachelor's degree recipient in a non-STEAM field, there were 2.5 entry-level job postings for a bachelor's degree recipient in a STEAM field.

What separates STEAM from traditional science and math education is the blended learning environment and showing students how the scientific method can be applied to everyday life. It teaches students computational thinking and focuses on the real-world applications of problem-solving. As mentioned before, STEAM education begins while students are very young:

Elementary school STEAM education focuses on the introductory level STEAM courses, as well as awareness of the STEAM fields and occupations. This initial step provides standards-based structured inquiry-based and real-world problem-based learning, connecting all four of the STEAM subjects. The goal is to pique students' interest into them wanting to pursue the courses, not because they have to. There is also an emphasis placed on bridging in-school and out-of-school STEAM learning opportunities.

Middle school At this stage, the courses become more rigorous and challenging. Student awareness of STEAM fields and occupations is still pursued, as well as the academic requirements of such fields. Student exploration of STEAM-related careers begins at this level, particularly for underrepresented populations.

High school The program of study focuses on the application of the subjects in a challenging and rigorous manner. Courses and pathways are now available in STEAM fields and occupations, as well as preparation for post-secondary education and employment. More emphasis is placed on bridging in-school and out-of-school STEAM opportunities.

Much of the STEAM curriculum is aimed toward attracting underrepresented populations. There is a significant disparity in the female to male ratio when it comes to those employed in STEAM fields, according to Stem Women (opens in new tab). Approximately 1 in 4 STEAM graduates is female.

Ethnically, people from Black backgrounds in STEAM education in the UK have poorer degree outcomes and lower rates of academic career progression compared to other ethnic groups, according to a report from The Royal Society (opens in new tab). Although the proportion of Black students in STEAM higher education has increased over the last decade, they are leaving STEAM careers at a higher rate compared to other ethnic groups.

"These reports highlight the challenges faced by Black researchers, but we also need to tackle the wider inequalities which exist across our society and prevent talented people from pursuing careers in science." President of the Royal Society, Sir Adrian Smith said.

Asian students typically have the highest level of interest in STEAM. According to the Royal Society report in 2018/19 18.7% of academic staff in STEAM were from ethnic minority groups, of these groups 13.2% were Asian compared to 1.7% who were Black.

If you want to learn more about why STEAM is so important check out this informative article from the University of San Diego (opens in new tab). Explore some handy STEAM education teaching resources courtesy of the Resilient Educator (opens in new tab). Looking for tips to help get children into STEAM? Forbes (opens in new tab) has got you covered.

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Science, Technology, Engineering, and Math, including Computer Science – ed

January 23rd, 2023 12:07 am

Today, the U.S. Department of Education (Department) will host the YOU Belong in STEM National Coordinating Conference in Washington, D.C. as a key initiative for the Biden-Harris Administration. The Raise the Bar: STEM Excellence for All Students initiative is designed to strengthen Science, Technology, Engineering and Mathematics (STEM) education nationwide. This new Biden-Harris Administration initiative will help implement and scale equitable, high-quality STEM education for all students from PreK to higher educationregardless of background to ensure their 21st century career readiness and global competitiveness.

Research shows how a sense of belonging in rich and rigorous classrooms is directly correlated to students long-term academic success. Moreover, the Departments Civil Rights Data Collection continues to demonstrate that students of color and students with disabilities are disproportionately excluded from learning opportunities in STEM, said U.S. Deputy Secretary of Education Cindy Marten. Today, we are saying unequivocally to all students and educators that they belong in STEM and that they deserve to have rigorous and relevant educational experiences that inspire and empower them to reach their full potential as productive, contributing members of our nations workforce.

In support of the initiative and its goals, the Department has:

The U.S. Department of Education invited STEM education entities to make bold commitment(s) to advance STEM education in America. We encourage you to consider the following parameters in developing your commitment:

In just three weeks, over 90 organizations and even individual educators from across the country have come forward to offer specific commitments to enhance STEM education for all. These commitments range from local grassroots efforts to initiatives that are national in scope. Those interested in joining this movement may submit a commitment here by December 31, 2022.

Albert Einstein Distinguished Educator Fellowship ProgramAmerican Federation of TeachersAmerican Institute of MathematicsAmerican University Game CenterAssociation of Science and Technology CentersBattelle/STEMxBeyond100KBlack Rocket ProductionsBreakthrough CollaborativeBrightmoor Urban Training LLCBrightSpark, Inc.Brown Toy BoxBrownSTEMCalifornia State University, Office of the ChancellorCarnegie Corporation of New YorkCenter for Energy Workforce DevelopmentCenter for Family Math at NAFSCECenter of Science and Industry (COSI)Challenger CenterChicago Public Schools - Pershing Magnet SchoolCode.orgCodeVCommunity Resources for ScienceComputer Science Teachers AssociationData Science 4 EveryoneDiscoverEEast Syracuse Minoa CSD STEM Learning EcoystemEdGE @ TERCEducate MaineEnCorps, Inc.FULL STEAM AHEAD LLC TNGGUSDHispanics for STEM IDRA & Lead of the Alamo STEM EcosystemIntel ArizonaInternational Technology and Engineering Educators AssociationIntrepid Sea, Air & Space Museum ISS National Laboratory JASON LearningKC STEM AllianceKids' Chemical Solutions Learning BladeLG Technical Services MDCPS/ TeachforAmericaMeharry School of Applied Computational SciencesMMSA/ Maine Mathematics and Science AllianceMSD of MartinsvilleNational Children's Museum

National Girls Collaborative ProjectNational Network of State Teachers of the YearNational Science Teaching AssociationNational Education AssociationNew Jersey Tutoring Corps IncNew York Hall of ScienceNI (formerly National Instruments)Niswonger Foundation / STEM.LDNorth Mason School DistrictNortheast Florida Regional STEM2 Hub, Inc. Ohio Afterschool NetworkOld Forge Elementary SchoolOut TeachOverdeck Family FoundationPartnerships in Education and Resilience (PEAR)Pennsylvania Statewide STEM EcosystemPhiladelphia Education Fund/Philadelphia STEM EcosystemPS ScienceS2TEM Centers SC/South Carolina Coalition of Mathematics and ScienceSAE FoundationScience is ElementarySHPE (Society of Hispanic Professional Engineers)Smithsonian Science Education Center, Smithsonian InstitutionSociety of Women EngineersSourcewell South Jersey STEM Innovation & PartnershipSTEM Next Opportunity FundSTEMpressarial INC.STEMSSTEMS4Girls, Inc. StudentTagpros Children InternationalTechbridge Girls Thaddeus Stevens College of TechnologyThe LEGO GroupThe New Mexico Out-of-School Time Network (NMOST)The University of Texas at Austin/ Texas Advanced Computing Center (TACC)The UTeach Institute at The University of Texas at AustinU.S. DOE Office of Elementary and Secondary EducationUnity Technologies University of HoustonUSD 457 and Kansas State Department of EducationU.S. Patent and Trademark OfficeWyoming Afterschool Alliance365 Productions Inc

BackgroundDepartment Offices that Support STEMExamples of the Department's discretionary grants that can support STEM Grant Applicant ResourcesCall for Peer ReviewersAmerica's Strategy for STEM EducationSecretary's STEM PriorityU.S. Department of Education STEM NewsletterArchived STEM NewslettersSTEM Education BriefingsUpcoming STEM BriefingsArchived STEM BriefingsResourcesOther Communications ToolsOther Federal Agency STEM WebsitesDepartment STEM Contacts

In an ever-changing, increasingly complex world, it's more important than ever that our nation's youth are prepared to bring knowledge and skills to solve problems, make sense of information, and know how to gather and evaluate evidence to make decisions. These are the kinds of skills that students develop in science, technology, engineering, and math, including computer sciencedisciplines collectively known as STEM/CS. If we want a nation where our future leaders, neighbors, and workers can understand and solve some of the complex challenges of today and tomorrow, and to meet the demands of the dynamic and evolving workforce, building students' skills, content knowledge, and literacy in STEM fields is essential. We must also make sure that, no matter where children live, they have access to quality learning environments. A child's zip code should not determine their STEM literacy and educational options.

Office of Planning, Evaluation, and Policy Development (OPEPD)Office of Career, Technical, and Adult Education (OCTAE)Office of Elementary and Secondary Education (OESE)Office of Special Education and Rehabilitative Services (OSERS)Office of Postsecondary Education (OPE)Office of Non-Public Education (ONPE)Office of Educational Technology (OET)Office of English Language Acquisition (OELA)Institute of Educational Sciences (IES)White House InitiativesFederal Student Aid (FSA)Office of Communications and Outreach (OCO)

Below are investments made in FY 2020:

You can search for open discretionary grant opportunities or reach out to the Department's STEM contacts noted below. The Forecast of Funding Opportunities lists virtually all Department discretionary grant programs for FY 2021.

The Department published in spring 2020 two new grant applicant resources. These resources were developed to (1) provide an overview of the discretionary (or competitive) grants application process and (2) offer more details intended to be used by prospective applicants, including new potential grantees. These support one of the Secretary's new administrative priorities on New Potential Grantees that was published in March 2020. They can also be found under the "Other Grant Information" on the ED's Grants webpage.

The Department is seeking peer reviewers for our Fiscal Year 2021 competitive/discretionary grant season, including in the STEM/CS areas (among others). The Federal Register notice spotlights the specific needs of the Office of Elementary and Secondary Education (OESE), the Office of Postsecondary Education (OPE), and the Office of Special Education and Rehabilitative Services (OSERS). The How to Become a Peer Reviewer slide deck provides additional information and next steps.

The STEM Education Strategic Plan, Charting a Course for Success: America's Strategy for STEM Education, published in December 2018, sets out a federal strategy for the next five years based on a vision for a future where all Americans will have lifelong access to high-quality STEM education and the United States will be the global leader in STEM literacy, innovation, and employment. It represents an urgent call to action for a nationwide collaboration with learners, families, educators, communities, and employersa "North Star" for the STEM community as it collectively charts a course for the Nation's success. The Department is an active participant in each of the interagency working groups focused on implementation of the Plan.

Learn more about what the Department and other federal agencies are doing to implement the plan in these progress reports:

Progress Reports

October 2019December 2020December 2021

Secretary Cardona finalized his six priorities for use in agency discretionary grant programs; equitable access to rigorous STEM, including computer science, experiences is noted in Priority 2. The Department also issued a revised set of common instructions for grant applicants.

In February 2020, the Department created the U.S. Department of Education STEM Newsletter. Please go to our newsletter subscription page to sign-up.

January 2023October/November 2022September 2022August 2022July 2022May 2022April 2022March 2022February 2022January 2022December 2021November 2021October 2021October 2021 AddendumSeptember 2021August 2021July 2021June 2021 May 2021 April 2021 January 2021 December 2020 November 2020 October 2020September 2020August 2020July 2020June 2020May 2020April 2020March 2020February 2020

The STEM Education Briefings are live-streamed, close-captioned and archived for your convenience.

There are no upcoming STEM briefings at this time.

November 15, 2022 Public Health and STEM with CDC (presentation slides [MS PowerPoint, 40MB])September 16, 2022 The Pathway to Convergence (presentation slides [MS PowerPoint, 77MB])July 19, 2022 Girls in STEM(21stCCLC Summer Symposium)April 26, 2022 Learning with NASA is Out of this WorldMarch 25, 2022 Science: Call to Action (presentation slides [MS PowerPoint, 22MB])February 24, 2022 Rural STEM Education (presentation slides [MS PowerPoint, 125MB])January 19, 2022 - Think Globally, Teach Locally (presentation slides [PDF, 10MB])December 9, 2021 Environmental LiteracyNovember 30, 2021 Energizing STEM (presentation slides [PDF, 6.7MB])October 15, 2021 Data Literacy (presentation slides [PDF, 12.6MB])July 28, 2021 Advanced Manufacturing: Industry of the Future (presentation slides [PDF, 11.3MB])May 4, 2021 Summertime STEM (presentation slides [PDF, 18.3MB])March 25, 2021 Differing Abilities in STEM, featuring Dr. Temple Grandin (presentation slides [PDF, 13.7MB])February 2021 Inspiring STEM Interest (presentation slides [PDF, 3.7MB])December 2020 New Frontiers in K-12 Computer Science (presentation slides [PDF, 12.7MB])November 2020 Federal STEM Strategic Plan: 2 Years Later (presentation slides [PDF, 15.49MB]).October 2020 Invention Education (presentation slides [PDF, 13.13MB])September 2020 STEM Teacher Preparation (presentation slides [PDF, 3.5MB])August 2020 Cybersecurity Education (presentation slides [PDF, 10.5MB])July 2020 Early Math (presentation slides [PDF, 2.37MB])June 2020 Distance LearningFebruary 2020 STEM After SchoolJanuary 2020 STEAM: Arts Supporting STEMDecember 2019 Family Engagement in STEMNovember 2019 The STEM Opportunity IndexOctober 2019 Early Engineering Education and State EffortsSeptember 2019 Recruiting and Retaining 100K STEM Teachers in 10 YearsJuly 2019 What Do We Know about Computer Science Education?

Assisting Students Struggling with Mathematics: Intervention in the Elementary GradesDesigning and Delivering Career Pathways at Community CollegesLearning in a Pandemic WebinarFall 2020 Back-to-School Success StoriesCOVID-19 Information and Resources for Schools and School PersonnelESEA, IDEA, and Perkins ResourcesCollege Scorecard updated again on 1/15/21Exploring Career Options FSAWork-Based LearningStackable Credentials that lead to careersCross-agency teacher resourcesIES data and statistics, research and evaluation, and tools for educatorsOut of School STEM InitiativesThe ED Games Expo "Goes Virtual" to Support Distance LearningSTEM Data Story A Leak in the STEM Pipeline: Taking Algebra EarlyCTE Data Story Bridging the Skills Gap: Career and Technical Education in High SchoolSTEM Spotlights Parent and Family Digital Learning GuideEarly Learning: STEM Math VideoKeep Calm and Connect All Student OET Blog SeriesK-12 Practitioners' CircleSTEM Innovation for Inclusion in Early Education (STEMI2E2) Center and OSEP's Early Learning NewsletterA Transition Guide to Postsecondary Education and Employment for Students and Youth with DisabilitiesCTE Research CenterCivil Rights Data CollectionDepartment's Data Strategy

Homeroom BlogPress ReleasesTwitterNewsletter Subscriptions

The following are federal agencies that the Department collaborates with to support the aims of the STEM Education Strategic Plan (see above section for more details) and support the Department's stakeholders.

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Science, Technology, Engineering, and Math, including Computer Science - ed

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What Does STEM Stand For? Definition, Degrees and More

January 23rd, 2023 12:07 am

Just because you have an interest in STEM (we assume you do since youre this far into the article), does that mean you have to give up on other pursuits? The humanities, which include everything from philosophy to anthropology to literature, might be an important part of who you are as a person too.

Thats why many in education have advocated for the inclusion of the arts in STEM education. And so the acronym STEAM was born!

Arts and humanities play an important part in many STEM careers. Its one thing, for instance, to design a phone thats more functional than the rest. Yet that phone may not sell as well without an attractive design that resonates with potential customers.

STEM fields help us find concrete answers to difficult questions; yet many problems do not have clear-cut solutions. Engineers working with self-driving cars, for example, have to reckon with difficult philosophical decision-making when designing these vehicles. If a self-driving car is about to hit a pedestrian, should it steer off the road, harming the driver but sparing the pedestrian? Its not a question that can be answered through mathematical equations or clever engineering.

Its to address problems like these that the humanities have been integrated into STEM education. The arts help workers in STEM fields figure out issues of subjectivity when objectivity wont cut it.

Understanding what STEM means, and how it figures into your education, can help you figure out the educational path thats right for you. Do you like working with computers to solve day-to-day business problems? Then an online IT degree might be a great choice. Maybe youd rather work out complex theoretical equations and discover the secrets of the universe. Get started with an introductory course in calculus.

Wherever you are in your educational journey, and wherever your interests lie, theres a STEM path for you!

Women have their own take on STEM. Check out how women working in tech overcome challenges to succeed.

Get started in your STEM journey with a technology degree from University of Phoenix!

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What Does STEM Stand For? Definition, Degrees and More

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What Is STEM? – Definition & Resources for Teachers

January 23rd, 2023 12:07 am

STEM might win the award for the most talked about education buzzword of the last 10 years or so. Its gotten to the point where, similar to the organic and low fat labels in the food industry, STEM could mean very little if you see it on toys or educational products. So how do we talk intelligently about STEM education and where it needs to go? The first step is understanding the history of this term and what it means for schools.

STEM stands for science, technology, engineering, and math. STEM curriculum blends those subjects in order to teach 21st-century skills, or tools students need to have if they wish tosucceed in the workplace of the future. The idea is that in order to be prepared for jobs and compete with students from different parts of the world, students here in the US need to be able to solve problems, find and use evidence, collaborate on projects, and think critically. Skills, the thinking goes, that are taught in those subjects.

Still, STEM can be hard to define. Its such a popular term that it means a lot of different things to a lot of different people. Although the science (biology, chemistry, etc.) and math (algebra, calculus, etc.) parts of the abbreviation might be easy to figure out, the technology and engineering parts might be less clear. Technology includes topics such as computer programming, analytics, and design. Engineering can include topics like electronics, robots, and civil engineering. The key term, when talking about STEM, is integration. STEM curriculum intentionally melds these disciplines. Its a blended approach that encourages hands-on experience and gives students the chance to gain and apply relevant, real-world knowledge in the classroom.

Like most things, STEM was around before it had an actual name. But STEM wasnt known as STEM until Dr. Judith Ramalay coined the term. While working as director at the National Science Foundation in the early 2000s, Ramalay came up with the term to describe the blended curriculum she and her team were developing. Referred to as SMET at first,which, if we had to guess, might also be the name of a Scandinavian dessert, Ramalay changed the acronym around because she didnt like how SMET sounded. So we (thankfully) got STEM.

STEM grew in popularity due to the concerns of politicians and other leaders that US students were not keeping pace with other students and would thus not be prepared to work in the fastest-growing career sectors, which generally fall under the STEM umbrella. In 2009, the Obama administration announced its plan to support STEM curriculum that would both encourage and train students to pursue careers in those fields. It would also support teachers to, well, teach students those skills. That effort has been formalized in many ways, including using the language of STEM in Next Gen Science Standards. So, teachers everywhere are expectedby parents, administrators, etc.to provide a STEM-rich curriculum.

We get it. STEM sounds like a lot. Theres a big difference between teaching students to remember to carry the one and teaching them how to code. But there are simple, unintimidating, and effective ways to implement a STEM curriculum in your classroom that has nothing to do with teaching R2D2 to dab.

If you teach younger students, create an environment that encourages observation and asking questions that begin with Why ? or How does ? Go on nature walks. Sing Old MacDonald Had a Farm and use it as a springboard to think about the ecosystem of a farm. Explore how simple classroom machines, like a stapler, work. Above all, its important to help students to get a solid foundation. Make sure they are fluent in basic skills like addition and subtraction, measurement, or identifying shapes.

For upper elementary and middle school students, consider project-based learning. Pose problems that students can relate to, can be solved in different ways, and let students work together and provide evidence of their thinking. Most importantly, students need to be able to pull from their knowledge of different subjects as they work toward an answer. The Association for Middle School Education, for example, provides several great scenarios that promote STEM learning. For instance, if there was an outbreak of illness at a carnival, how would your students solve that problem? Or, even more broadly, how might they create a community of the future?

High school students, especially juniors or seniors, should definitely be thinking about college and beyond. Do you have a student or two who might make a great crime scene investigator? How might you bring a version of the board game Clue into the classroom? Help students use forensic science and their investigative skills to determine whodunit and the cause of death. What math skills do they need to know to come up with the analytics to predict the next NBA champion? Or, have students run analytics for previous seasons and compare their results to what really happened.

Theres no I in team. Theres also no A in STEMuntil recently. Asking questions, using evidence, and working well with others to solve problems are not skills taught only in the hard sciences. Excellent humanities and social science curricula teach these tools as well. And they engage students creativity and imagination. As such, theres a growing movement to incorporate more arts and humanities subjects into STEM curriculum. This is a great co-teaching opportunity. How might your English class join up with science students in the previously mentioned Clue scenario? Maybe they can write a backstory. Perhaps another group of students can design and build a scale version of the crime scene. There are lots of possibilities. Above all, whether its STEM or STEAM, your plan should encourage cross-curricular activities and inspire students to use and gain knowledge in exciting ways.

WeAreTeachers has some excellent STEM and STEAM resources. Check out some of them:

How do you STEM your curriculum? Come share in ourWeAreTeachers HELPLINE groupon Facebook.

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What Is STEM? - Definition & Resources for Teachers

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Science, technology, engineering, and mathematics – Wikipedia

January 23rd, 2023 12:07 am

Group of academic disciplines

Science, technology, engineering, and mathematics (STEM) is an umbrella term used to group together the distinct but related technical disciplines of science, technology, engineering, and mathematics. The term is typically used in the context of education policy or curriculum choices in schools. It has implications for workforce development, national security concerns (as a shortage of STEM-educated citizens can reduce effectiveness in this area) and immigration policy.[1]

There is no universal agreement on which disciplines are included in STEM; in particular whether or not the science in STEM includes social sciences, such as psychology, sociology, economics, and political science. In the United States, these are typically included by organizations such as the National Science Foundation (NSF),[1] the Department of Labor's O*Net online database for job seekers,[2] and the Department of Homeland Security.[3] In the United Kingdom, the social sciences are categorized separately and are instead grouped together with humanities and arts to form another counterpart acronym HASS (Humanities, Arts, and Social Sciences), rebranded in 2020 as SHAPE (Social Sciences, Humanities and the Arts for People and the Economy).[4][5]

In the early 1990s, the acronym STEM was used by a variety of educators in preference to SMET, including Charles E. Vela, the founder and director of the Center for the Advancement of Hispanics in Science and Engineering Education (CAHSEE).[6][7][8] Moreover, the CAHSEE started a summer program for talented under-represented students in the Washington, DC area called the STEM Institute. Based on the program's recognized success and his expertise in STEM education,[9] Charles Vela was asked to serve on numerous NSF and Congressional panels in science, mathematics and engineering education;[10] it is through this manner that NSF was first introduced to the acronym STEM. One of the first NSF projects to use the acronym was STEMTEC, the Science, Technology, Engineering and Math Teacher Education Collaborative at the University of Massachusetts Amherst, which was founded in 1998.[11]In 2001, at the urging of Dr. Peter Faletra, the Director of Workforce Development for Teachers and Scientists at the Office of Science, the acronym was adopted by Rita Colwell and other science administrators in the National Science Foundation (NSF). The Office of Science was also an early adopter of the STEM acronym.[12]

The Australian Curriculum, Assessment and Reporting Authority 2015 report entitled, National STEM School Education Strategy, stated that "A renewed national focus on STEM in school education is critical to ensuring that all young Australians are equipped with the necessary STEM skills and knowledge that they must need to succeed."[30] Its goals were to:

Events and programs meant to help develop STEM in Australian schools include the Victorian Model Solar Vehicle Challenge, the Maths Challenge (Australian Mathematics Trust),[31] Go Girl Go Global[31] and the Australian Informatics Olympiad.[31]

Canada ranks 12th out of 16 peer countries in the percentage of its graduates who studied in STEM programs, with 21.2%, a number higher than the United States, but lower than France, Germany, and Austria. The peer country with the greatest proportion of STEM graduates, Finland, has over 30% of its university graduates coming from science, mathematics, computer science, and engineering programs.[32]

SHAD is an annual Canadian summer enrichment program for high-achieving high school students in July. The program focuses on academic learning particularly in STEAM fields.[33]

Scouts Canada has taken similar measures to their American counterpart to promote STEM fields to youth. Their STEM program began in 2015.[34]

In 2011 Canadian entrepreneur and philanthropist Seymour Schulich established the Schulich Leader Scholarships, $100 million in $60,000 scholarships for students beginning their university education in a STEM program at 20 institutions across Canada. Each year 40 Canadian students would be selected to receive the award, two at each institution, with the goal of attracting gifted youth into the STEM fields.[35] The program also supplies STEM scholarships to five participating universities in Israel.[36]

To promote STEM in China, the Chinese government issued a guideline in 2016 on national innovation-driven development strategy, instructing that by 2020, China should become an innovative country; by 2030, it should be at the forefront of innovative countries; and by 2050, it should become a technology innovation power.[citation needed]

In February 2017, the Ministry of Education in China announced they would officially add STEM education to the primary school curriculum, which is the first official government recognition of STEM education. And later, in May 2018, the launching ceremony and press conference for the 2029 Action Plan for China's STEM Education was held in Beijing, China. This plan aims to allow as many students to benefit from STEM education as possible and equip all students with scientific thinking and the ability to innovate. In response to encouraging policies by the government, schools in both public and private sectors around the country have begun to carry out STEM education programs.[citation needed]

However, to effectively implement STEM curricula, full-time teachers specializing in STEM education and relevant content to be taught are needed. Currently, China lacks qualified STEM teachers, and a training system is yet to be established.[citation needed]

Several Chinese cities have taken bold measures to add programming as a compulsory course for elementary and middle school students. This is the case of the city of Chongqing.[citation needed]

Several European projects have promoted STEM education and careers in Europe. For instance, Scientix[37] is a European cooperation of STEM teachers, education scientists, and policymakers. The SciChallenge[38] project used a social media contest and the student-generated content to increase motivation of pre- university students for STEM education and careers. The Erasmus programme project AutoSTEM[39] used automata to introduce STEM subjects to very young children.

In Finland LUMA Center is the leading advocate for STEM oriented education. In the native tongue luma stands for "luonnontieteellis-matemaattinen" (lit. adj. "scientific-mathematical"). The short is more or less a direct translation of STEM, with engineering fields included by association. However unlike STEM, the term is also a portmanteau from lu and ma.

The name of STEM in France is industrial engineering sciences (sciences industrielles or sciences de l'ingnieur). The STEM organization in France is the association UPSTI.[clarification needed]

STEM education has not been promoted among the local schools in Hong Kong until recent years. In November 2015, the Education Bureau of Hong Kong released a document titled Promotion of STEM Education,[40] which proposes strategies and recommendations on promoting STEM education.

India is next only to China with STEM graduates per population of 1 to 52. The total fresh STEM graduates were 2.6 million in 2016.[41] STEM graduates have been contributing to the Indian economy with well paid salaries locally and abroad since last two decades. The turnaround of Indian economy with comfortable foreign exchange reserves is mainly attributed to the skills of its STEM graduates.

In Nigeria, The Association of Professional Women Engineers Of Nigeria (APWEN) has involved girls between the ages of 12 to 19 in science based courses in other for them to pursue science based courses in the higher institutions of learning. National Science Foundation (NSF) In Nigeria has made conscious efforts to encourage girls to innovate, invent and build it through the 'invent it, build it challenge' program sponsored by NNPC.[42]

STEM subjects are taught in Pakistan as part of electives taken in the 9th and 10th grade, culminating in Matriculation exams. These electives are: pure sciences (Physics, Chemistry, Biology), mathematics (Physics, Chemistry, Maths) and computer science (Physics, Chemistry, Computer Science). STEM subjects are also offered as electives taken in the 11th and 12th grade, more commonly referred to as first and second year, culminating in Intermediate exams. These electives are: FSc pre-medical (Physics, Chemistry, Biology), FSc pre-engineering (Physics, Chemistry, Maths) and ICS (Physics/Statistics, Computer Science, Maths). These electives are intended to aid students in pursuing STEM-related careers in the future by preparing them for the study of these courses at university.

A STEM education project has been approved by the government[43] to establish STEM labs in public schools. The Ministry of Information Technology and Telecommunication has collaborated with Google to launch Pakistan's first grassroots level Coding Skills Development Program,[44] based on Google's CS First Program, a global initiative aimed at developing coding skills in children. The aim of the program is to develop applied coding skills using gamification techniques for children between the ages of 9 and 14.

The KPITBs Early Age Programming initiative,[45] established in the province of Khyber Pakhtunkhwa, has been successfully introduced in 225 Elementary and Secondary Schools. There are many private organizations working in Pakistan to introduce STEM education in schools.

In the Philippines, STEM is a two-year program and strand that is used for Senior High School (Grade 11 and 12), as signed by the Department of Education or DepEd. The STEM strand is under the Academic Track, which also include other strands like ABM, HUMSS, and GAS.[46][47] The purpose of STEM strand is to educate students in the field of science, technology, engineering, and mathematics, in an interdisciplinary and applied approach, and to give students advance knowledge and application in the field. After completing the program, the students will earn a Diploma in Science, Technology, Engineering, and Mathematics. In some colleges and universities, they require students applying for STEM degrees (like medicine, engineering, computer studies, etc.) to be a graduate of STEM, if not, they will need to enter a bridging program.

In Qatar, AL-Bairaq is an outreach program to high-school students with a curriculum that focuses on STEM, run by the Center for Advanced Materials (CAM) at Qatar University. Each year around 946 students, from about 40 high schools, participate in AL-Bairaq competitions.[48] AL-Bairaq make use of project-based learning, encourages students to solve authentic problems, and inquires them to work with each other as a team to build real solutions.[49][50] Research has so far shown positive results for the program.[51]

STEM is part of the Applied Learning Programme (ALP) that the Singapore Ministry of Education (MOE) has been promoting since 2013, and currently, all secondary schools have such a programme. It is expected that by 2023, all primary schools in Singapore will have an ALP. There are no tests or exams for ALPs. The emphasis is for students to learn through experimentation they try, fail, try, learn from it and try again. The MOE actively supports schools with ALPs to further enhance and strengthen their capabilities and programmes that nurtures innovation and creativity.

The Singapore Science Centre established a STEM unit in January 2014, dedicated to igniting students passion for STEM. To further enrich students learning experiences, their Industrial Partnership Programme (IPP) creates opportunities for students to get early exposure to the real-world STEM industries and careers. Curriculum specialists and STEM educators from the Science Centre will work hand-in-hand with teachers to co-develop STEM lessons, provide training to teachers and co-teach such lessons to provide students with an early exposure and develop their interest in STEM.

In 2017, Thai Education Minister Dr Teerakiat Jareonsettasin said after the 49th Southeast Asia Ministers of Education Organisation (SEAMEO) Council Conference in Jakarta that the meeting approved the establishment of two new SEAMEO regional centres in Thailand. One would be the STEM Education Centre, while the other would be a Sufficient Economy Learning Centre.

Teerakiat said that the Thai government had already allocated Bt250 million over five years for the new STEM centre. The centre will be the regional institution responsible for STEM education promotion. It will not only set up policies to improve STEM education, but it will also be the centre for information and experience sharing among the member countries and education experts. According to him, This is the first SEAMEO regional centre for STEM education, as the existing science education centre in Malaysia only focuses on the academic perspective. Our STEM education centre will also prioritise the implementation and adaptation of science and technology.[52]

The Institute for the Promotion of Teaching Science and Technology has initiated a STEM Education Network. Its goals are to promote integrated learning activities and improve student creativity and application of knowledge, and to establish a network of organisations and personnel for the promotion of STEM education in the country.[53]

Turkish STEM Education Task Force (or FeTeMMFen Bilimleri, Teknoloji, Mhendislik ve Matematik) is a coalition of academicians and teachers who show an effort to increase the quality of education in STEM fields rather than focussing on increasing the number of STEM graduates.[54][55]

In the United States, the acronym began to be used in education and immigration debates in initiatives to begin to address the perceived lack of qualified candidates for high-tech jobs. It also addresses concern that the subjects are often taught in isolation, instead of as an integrated curriculum.[56] Maintaining a citizenry that is well versed in the STEM fields is a key portion of the public education agenda of the United States.[57] The acronym has been widely used in the immigration debate regarding access to United States work visas for immigrants who are skilled in these fields. It has also become commonplace in education discussions as a reference to the shortage of skilled workers and inadequate education in these areas.[58] The term tends not to refer to the non-professional and less visible sectors of the fields, such as electronics assembly line work.

Many organizations in the United States follow the guidelines of the National Science Foundation on what constitutes a STEM field. The NSF uses a broader definition of STEM subjects that includes subjects in the fields of chemistry, computer and information technology science, engineering, geosciences, life sciences, mathematical sciences, physics and astronomy, social sciences (anthropology, economics, psychology and sociology), and STEM education and learning research.[1][59]The NSF is the only American federal agency whose mission includes support for all fields of fundamental science and engineering, except for medical sciences.[60] Its disciplinary program areas include scholarships, grants, fellowships in fields such as biological sciences, computer and information science and engineering, education and human resources, engineering, environmental research and education, geosciences, international science and engineering, mathematical and physical sciences, social, behavioral and economic sciences, cyberinfrastructure, and polar programs.[59]

Although many organizations in the United States follow the guidelines of the National Science Foundation on what constitutes a STEM field, the United States Department of Homeland Security (DHS) has its own functional definition used for immigration policy.[61] In 2012, DHS or ICE announced an expanded list of STEM designated-degree programs that qualify eligible graduates on student visas for an optional practical training (OPT) extension. Under the OPT program, international students who graduate from colleges and universities in the United States can stay in the country and receive up to twelve months of training through work experience. Students who graduate from a designated STEM degree program can stay for an additional seventeen months on an OPT STEM extension.[62][63]

An exhaustive list of STEM disciplines does not exist because the definition varies by organization. The U.S. Immigration and Customs Enforcement lists disciplines including[64] architecture, physics, actuarial science, chemistry, biology, mathematics, applied mathematics, statistics, computer science, computational science, psychology, biochemistry, robotics, computer engineering, electrical engineering, electronics, mechanical engineering, industrial engineering, information science, information technology, civil engineering, aerospace engineering, chemical engineering, astrophysics, astronomy, optics, nanotechnology, nuclear physics, mathematical biology, operations research, neurobiology, biomechanics, bioinformatics, acoustical engineering, geographic information systems, atmospheric sciences, educational/instructional technology, software engineering, and educational research.

By cultivating an interest in the natural and social sciences in preschool or immediately following school entry, the chances of STEM success in high school can be greatly improved.[citation needed]

STEM supports broadening the study of engineering within each of the other subjects, and beginning engineering at younger grades, even elementary school. It also brings STEM education to all students rather than only the gifted programs. In his 2012 budget, President Barack Obama renamed and broadened the "Mathematics and Science Partnership (MSP)" to award block grants to states for improving teacher education in those subjects.[65]

In the 2015 run of the international assessment test the Program for International Student Assessment (PISA), American students came out 35th in mathematics, 24th in reading and 25th in science, out of 109 countries. The United States also ranked 29th in the percentage of 24-year-olds with science or mathematics degrees.[66]

STEM education often uses new technologies such as RepRap 3D printers to encourage interest in STEM fields.[67]

In 2006 the United States National Academies expressed their concern about the declining state of STEM education in the United States. Its Committee on Science, Engineering, and Public Policy developed a list of 10 actions. Their top three recommendations were to:

The National Aeronautics and Space Administration also has implemented programs and curricula to advance STEM education in order to replenish the pool of scientists, engineers and mathematicians who will lead space exploration in the 21st century.[68]

Individual states, such as California, have run pilot after-school STEM programs to learn what the most promising practices are and how to implement them to increase the chance of student success.[69] Another state to invest in STEM education is Florida, where Florida Polytechnic University,[70] Florida's first public university for engineering and technology dedicated to science, technology, engineering and mathematics (STEM), was established.[71] During school, STEM programs have been established for many districts throughout the U.S. Some states include New Jersey, Arizona, Virginia, North Carolina, Texas, and Ohio.[72][73]

Continuing STEM education has expanded to the post-secondary level through masters programs such as the University of Maryland's STEM Program[74] as well as the University of Cincinnati.[75]

In the United States, the National Science Foundation found that the average science score on the 2011 National Assessment of Educational Progress was lower for black and Hispanic students than white, Asian, and Pacific Islanders.[76] In 2011, eleven percent of the U.S. workforce was black, while only six percent of STEM workers were black.[77] Though STEM in the U.S. has typically been dominated by white males, there have been considerable efforts to create initiatives to make STEM a more racially and gender diverse field.[78] Some evidence suggests that all students, including black and Hispanic students, have a better chance of earning a STEM degree if they attend a college or university at which their entering academic credentials are at least as high as the average student's.[79] However, there is criticism that emphasis on STEM diversity has lowered academic standards.[80]

Although women make up 47% of the workforce[81] in the U.S., they hold only 24% of STEM jobs. Research suggests that exposing girls to female inventors at a young age has the potential to reduce the gender gap in technical STEM fields by half.[82] Campaigns from organizations like the National Inventors Hall of Fame aimed to achieve a 50/50 gender balance in their youth STEM programs by 2020.

In the State of the Union Address on January 31, 2006, President George W. Bush announced the American Competitiveness Initiative. Bush proposed the initiative to address shortfalls in federal government support of educational development and progress at all academic levels in the STEM fields. In detail, the initiative called for significant increases in federal funding for advanced R&D programs (including a doubling of federal funding support for advanced research in the physical sciences through DOE) and an increase in U.S. higher education graduates within STEM disciplines.

The NASA Means Business competition, sponsored by the Texas Space Grant Consortium, furthers that goal. College students compete to develop promotional plans to encourage students in middle and high school to study STEM subjects and to inspire professors in STEM fields to involve their students in outreach activities that support STEM education.

The National Science Foundation has numerous programs in STEM education, including some for K12 students such as the ITEST Program that supports The Global Challenge Award ITEST Program. STEM programs have been implemented in some Arizona schools. They implement higher cognitive skills for students and enable them to inquire and use techniques used by professionals in the STEM fields.

Project Lead The Way (PLTW) is a provider of STEM education curricular programs to middle and high schools in the United States. Programs include a high school engineering curriculum called Pathway To Engineering, a high school biomedical sciences program, and a middle school engineering and technology program called Gateway To Technology. PLTW programs have been endorsed by President Barack Obama and United States Secretary of Education Arne Duncan as well as various state, national, and business leaders.[citation needed]

The Science, Technology, Engineering, and Mathematics (STEM) Education Coalition[83] works to support STEM programs for teachers and students at the U. S. Department of Education, the National Science Foundation, and other agencies that offer STEM-related programs. Activity of the STEM Coalition seems to have slowed since September 2008.

In 2012, the Boy Scouts of America began handing out awards, titled NOVA and SUPERNOVA, for completing specific requirements appropriate to scouts' program level in each of the four main STEM areas. The Girl Scouts of the USA has similarly incorporated STEM into their program through the introduction of merit badges such as "Naturalist" and "Digital Art".[84]

SAE is an international organization, solutions'provider specialized on supporting education, award and scholarship programs for STEM matters, from pre-K to the college degree.[85] It also promotes scientific and technologic innovation.

[86]The eCybermission is a free, web-based science, mathematics and technology competition for students in grades six through nine sponsored by the U.S. Army. Each webinar is focused on a different step of the scientific method and is presented by an experienced eCybermission CyberGuide. CyberGuides are military and civilian volunteers with a strong background in STEM and STEM education, who are able to provide valuable insight into science, technology, engineering, and mathematics to students and team advisers.

STARBASE is a premier educational program, sponsored by the Office of the Assistant Secretary of Defense for Reserve Affairs. Students interact with military personnel to explore careers and make connections with the "real world." The program provides students with 2025 hours of stimulating experiences at National Guard, Navy, Marines, Air Force Reserve and Air Force bases across the nation.

SeaPerch is an innovative underwater robotics program that trains teachers to teach their students how to build an underwater remotely operated vehicle (ROV) in an in-school or out-of-school setting. Students build the ROV from a kit composed of low-cost, easily accessible parts, following a curriculum that teaches basic engineering and science concepts with a marine engineering theme.

NASAStem is a program of the U.S. space agency NASA to increase diversity within its ranks, including age, disability, and gender as well as race/ethnicity.[87]

The America COMPETES Act (P.L. 11069) became law on August 9, 2007. It is intended to increase the nation's investment in science and engineering research and in STEM education from kindergarten to graduate school and postdoctoral education. The act authorizes funding increases for the National Science Foundation, National Institute of Standards and Technology laboratories, and the Department of Energy (DOE) Office of Science over FY2008FY2010. Robert Gabrys, Director of Education at NASA's Goddard Space Flight Center, articulated success as increased student achievement, early expression of student interest in STEM subjects, and student preparedness to enter the workforce.

In November 2012 the White House announcement before congressional vote on the STEM Jobs Act put President Obama in opposition to many of the Silicon Valley firms and executives who bankrolled his re-election campaign.[88] The Department of Labor identified 14 sectors that are "projected to add substantial numbers of new jobs to the economy or affect the growth of other industries or are being transformed by technology and innovation requiring new sets of skills for workers."[89] The identified sectors were as follows: advanced manufacturing, Automotive, construction, financial services, geospatial technology, homeland security, information technology, Transportation, Aerospace, Biotechnology, energy, healthcare, hospitality, and retail.

The Department of Commerce notes STEM fields careers are some of the best-paying and have the greatest potential for job growth in the early 21st century. The report also notes that STEM workers play a key role in the sustained growth and stability of the U.S. economy, and training in STEM fields generally results in higher wages, whether or not they work in a STEM field.[90]

In 2015, there were around 9.0 million STEM jobs in the United States, representing 6.1% of American employment. STEM jobs were increasing around 9% percent per year.[91] Brookings Institution found that the demand for competent technology graduates will surpass the number of capable applicants by at least one million individuals.

According to Pew Research Center, a typical STEM worker earns two-thirds more than those employed in other fields.[92]

According to the 2014 US Census "74 percent of those who have a bachelor's degree in science, technology, engineering and math commonly referred to as STEM are not employed in STEM occupations."[93][94]

In September 2017, a number of large American technology firms collectively pledged to donate $300 million for computer science education in the U.S.[95]

PEW findings revealed in 2018 that Americans identified several issues that hound STEM education which included unconcerned parents, disinterested students, obsolete curriculum materials, and too much focus on state parameters. 57 percent of survey respondents pointed out that one main problem of STEM is lack of students' concentration in learning.[96]

The recent National Assessment of Educational Progress (NAEP) report card[97] made public technology as well as engineering literacy scores which determines whether students have the capability to apply technology and engineering proficiency to real-life scenarios. The report showed a gap of 28 points between low-income students and their high-income counterparts. The same report also indicated a 38-point difference between white and black students.[98]

The Smithsonian Science Education Center (SSEC) announced the release of a five-year strategic plan by the Committee on STEM Education of the National Science and Technology Council on December 4, 2018. The plan is entitled "Charting a Course for Success: America's Strategy for STEM Education."[99] The objective is to propose a federal strategy anchored on a vision for the future so that all Americans are given permanent access to premium-quality education in Science, Technology, Engineering, and Mathematics. In the end, the United States can emerge as world leader in STEM mastery, employment, and innovation. The goals of this plan are building foundations for STEM literacy; enhancing diversity, equality, and inclusion in STEM; and preparing the STEM workforce for the future.[100]

The 2019 fiscal budget proposal of the White House supported the funding plan in President Donald Trump's Memorandum on STEM Education which allocated around $200 million (grant funding) on STEM education every year. This budget also supports STEM through a grant program worth $20 million for career as well as technical education programs.[101]

In Vietnam, beginning in 2012 many private education organizations have STEM education initiatives.

In 2015, the Ministry of Science and Technology and Lin minh STEM organized the first National STEM day, followed by many similar events across the country.

in 2015, Ministry of Education and Training included STEM as an area needed to be encouraged in national school year program.

In May 2017, Prime Minister signed a Directive no. 16[102] stating: "Dramatically change the policies, contents, education and vocational training methods to create a human resource capable of receiving new production technology trends, with a focus on promoting training in science, technology, engineering and mathematics (STEM), foreign languages, information technology in general education; " and asking "Ministry of Education and Training (to): Promote the deployment of science, technology, engineering and mathematics (STEM) education in general education program; Pilot organize in some high schools from 2017 to 2018.

Women constitute 47% of the U.S. workforce, and perform 24% of STEM-related jobs.[103] In the UK women perform 13% of STEM-related jobs (2014).[104] In the U.S. women with STEM degrees are more likely to work in education or healthcare rather than STEM fields compared with their male counterparts.

The gender ratio depends on field of study. For example, in the European Union in 2012 women made up 47.3% of the total, 51% of the social sciences, business and law, 42% of the science, mathematics and computing, 28% of engineering, manufacturing and construction, and 59% of PhD graduates in Health and Welfare.[105]

In a study from 2019 it was shown that part of the success of women in STEM depends on the way women in STEM are viewed. In a study that researched grants given based primarily on project versus primarily based on the project lead there was almost no difference in the evaluation between projects from men or women when evaluated on project, but those evaluated mainly on the project leader showed that projects headed by women were given grants four percent less often.[106]

Improving the experiences of women in STEM is a major component of increasing the number of women in STEM. One part of this includes the need for role models and mentors who are women in STEM. Along with this, having good resources for information and networking opportunities can improve women's ability to flourish in STEM fields.[107]

People identifying within the group LGBTQ+ have faced discrimination in STEM fields throughout history. Few were openly queer in STEM; however, a couple of well-known people are Alan Turing, the father of computer science, and Sara Josephine Baker, American physician and public-health leader.[108]

Despite recent changes in attitudes towards LGBTQ+ people, discrimination still permeates throughout STEM fields.[109][110] A recent study has shown that gay men are less likely to have completed a bachelor's degree in a STEM field and to work in a STEM occupation.[111][112] Along with this, those of sexual minorities overall have been shown to be less likely to remain in STEM majors throughout college.[110] Another study concluded that queer people are more likely to experience exclusion, harassment and other negative impacts while in a STEM career while also having fewer opportunities and resources available to them.[113]

Multiple programs and institutions are working towards increasing the inclusion and acceptance of LGBTQ+ people in STEM. In the US, the National Organization of Gay and Lesbian Scientists and Technical Professionals (NOGLSTP) has organized people to address homophobia since the 1980s and now promotes activism and support for queer scientists.[114] Other programs, including 500 Queer Scientists and Pride in STEM, function as visibility campaigns for LGBTQ+ people in STEM worldwide.[114][115]

The focus on increasing participation in STEM fields has attracted criticism. In the 2014 article "The Myth of the Science and Engineering Shortage" in The Atlantic, demographer Michael S. Teitelbaum criticized the efforts of the U.S. government to increase the number of STEM graduates, saying that, among studies on the subject, "No one has been able to find any evidence indicating current widespread labor market shortages or hiring difficulties in science and engineering occupations that require bachelor's degrees or higher", and that "Most studies report that real wages in manybut not allscience and engineering occupations have been flat or slow-growing, and unemployment as high or higher than in many comparably-skilled occupations." Teitelbaum also wrote that the then-current national fixation on increasing STEM participation paralleled previous U.S. government efforts since World War II to increase the number of scientists and engineers, all of which he stated ultimately ended up in "mass layoffs, hiring freezes, and funding cuts"; including one driven by the Space Race of the late 1950s and 1960s, which he wrote led to "a bust of serious magnitude in the 1970s."[116]

IEEE Spectrum contributing editor Robert N. Charette echoed these sentiments in the 2013 article "The STEM Crisis Is a Myth", also noting that there was a "mismatch between earning a STEM degree and having a STEM job" in the United States, with only around 14 of STEM graduates working in STEM fields, while less than half of workers in STEM fields have a STEM degree.[117]

Economics writer Ben Casselman, in a 2014 study of post-graduation earnings in the United States for FiveThirtyEight, wrote that, based on the data, science should not be grouped with the other three STEM categories, because, while the other three generally result in high-paying jobs, "many sciences, particularly the life sciences, pay below the overall median for recent college graduates."[118]

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Stem Definition & Meaning – Merriam-Webster

January 23rd, 2023 12:07 am

1

specifically : a primary plant axis that develops buds and shoots instead of roots

: a plant part (such as a branch, petiole, or stipe) that supports another (such as a leaf or fruit)

: the complete fruiting stalk of a banana plant with its bananas

2

: the main upright member at the bow of a ship

3

especially : a fundamental line from which others have arisen

4

5

: something held to resemble a plant stem: such as

: a main or heavy stroke of a letter

: the short perpendicular line extending from the head of a musical note

: the part of a tobacco pipe from the bowl outward

: a shaft of a watch used for winding

transitive verb

1

: to make headway against (something, such as an adverse tide, current, or wind)

2

: to check or go counter to (something adverse)

transitive verb

1

: to remove the stem from

2

: to make a stem for (something, such as an artificial flower)

intransitive verb

transitive verb

1

: to stop or dam up (something, such as a river)

intransitive verb

1

also : to become checked or stanched

2

: to slide the heel of one ski or of both skis outward usually in making or preparing to make a turn

2

science, technology, engineering, and mathematics

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Blindness and vision impairment – World Health Organization

January 23rd, 2023 12:05 am

The International Classification of Diseases 11 (2018) classifies vision impairment into two groups, distance and near presenting vision impairment.

Distance vision impairment:

Near vision impairment:

Globally, at least 2.2 billion people have a near or distance vision impairment. In at least 1 billion or almost half of these cases, vision impairment could have been prevented or has yet to be addressed.

This 1 billion people includes those with moderate or severe distance vision impairment or blindness due to unaddressed refractive error (88.4 million), cataract (94 million), age-related macular degeneration (8 million), glaucoma (7.7 million), diabeticretinopathy (3.9 million) (1), as well as near vision impairment caused by unaddressed presbyopia (826 million)(2).

In terms of regional differences, the prevalence of distance vision impairment in low- and middle-income regions is estimated to be four times higher than in high-income regions (1). With regards to near vision, rates of unaddressed near vision impairmentare estimated to be greater than 80% in western, eastern and central sub-Saharan Africa, while comparative rates in high-income regions of North America, Australasia, Western Europe, and of Asia-Pacific are reported to be lower than 10% (2).

Population growth and ageing are expected to increase the risk that more people acquire vision impairment.

Globally, the leading causes of vision impairment are:

There is substantial variation in the causes between and within countries according to the availability of eye care services, their affordability, and the eye care literacy of the population. For example, the proportion of vision impairment attributableto cataract is higher in low- and middle-income countries than high-income countries. In high income countries, diseases such as glaucoma and age-related macular degeneration are more common.

Among children, the causes of vision impairment vary considerably across countries. For example, in low-income countries congenital cataract is a leading cause, whereas in middle-income countries it is more likely to be retinopathy of prematurity.

As in adult populations, uncorrected refractive error remains a leading cause of vision impairment in all countries amongst children.

Personal impact

Young children with early onset severe vision impairment can experience delayed motor, language, emotional, social and cognitive development, with lifelong consequences. School-age children with vision impairment can also experience lower levels of educationalachievement.

Vision impairment severely impacts quality of life among adult populations. Adults with vision impairment often have lower rates of workforce participation and productivity and higher rates of depression and anxiety.

In the case of older adults, vision impairment can contribute to social isolation, difficulty walking, a higher risk of falls and fractures, and a greater likelihood of early entry into nursing or care homes.

Economic impact

Vision impairment poses an enormous global financial burden with an estimate annual global productivity loss of about US$ 411 billion purchasing power parity (3). this figure far outweighs the estimated cost gap of addressing the unmet need of visionimpairment (estimated at about US$ 25 billion).

While a large number of eye diseases can be prevented (such as infections, trauma, unsafe traditional medicines, perinatal diseases, nutrition-related diseases, unsafe use or self-administration of topical treatment), this is not possible for all.

Each eye condition requires a different, timely response. There are effective interventions covering promotion, prevention, treatment and rehabilitation which address the needs associated with eye conditions and vision impairment; some are among the mostcost-effective and feasible of all health care interventions to implement. For example, uncorrected refractive error can be corrected with spectacles or surgery while cataract surgery can restore vision.

Treatment is also available for many eye conditions that do not typically cause vision impairment, such as dry eye, conjunctivitis and blepharitis, but generate discomfort and pain. Treatment of these conditions is directed at alleviating the symptomsand preventing the evolution towards more severe diseases.

Vision rehabilitation is very effective in improving functioning for people with an irreversible vision impairment that can be caused by eye conditions such as diabetic retinopathy, glaucoma, consequences of trauma, and age-related macular degeneration.

WHOs work is guided by the recommendations of the WHO World report on vision (2019) and the resolution on "integrated, people-centred eye care, including preventable blindness and vision impairment"thatwas adopted at Seventy-third World Health Assembly in 2020. The key proposal of the report and resolution is to make integrated people-centred eye care (IPEC) the care model of choice and to ensure its widespread implementation. It is expected thatby shaping the global agenda on vision, the report and resolution will assist Member States and their partners in their efforts to reduce the burden of eye conditions and vision impairment and achieve the Sustainable Development Goals (SDGs), particularlySDG target 3.8 on universal health coverage.

Some of WHOs key areas of work and activities in the prevention of blindness include:

1) GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation toVISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study. Lancet Glob Health. 2021 Feb;9(2):e144-e160. doi: 10.1016/S2214-109X(20)30489-7.

2) Fricke, TR, Tahhan N, Resnikoff S, Papas E, Burnett A, Suit MH, Naduvilath T, Naidoo K, Global Prevalence of Presbyopia and Vision Impairment from Uncorrected Presbyopia: Systematic Review, Meta-analysis, and Modelling, Ophthalmology. 2018 May 9.

3) Burton MJ, Ramke J, Marques AP, Bourne RR, Congdon N, Jones I, et al. The Lancet Global Health commission on Global Eye Health: vision beyond 2020. Lancet Glob Health. 2021; 9(4):e489e551.

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Recovery from blindness – Wikipedia

January 23rd, 2023 12:05 am

Recovery from blindness is the phenomenon of a blind person gaining the ability to see, usually as a result of medical treatment. As a thought experiment, the phenomenon is usually referred to as Molyneux's problem. It is often stated that the first published human case was reported in 1728 by the surgeon William Cheselden. However, there is no evidence that Cheselden's patient, a boy named Daniel Dolins, actually recovered any vision.[1] Patients who experience dramatic recovery from blindness experience significant to total agnosia, having serious confusion with their visual perception.

The phenomenon has often been presented in empiricism as a thought experiment, in order to describe the knowledge gained from senses, andquestion the correlation between different senses.

John Locke, an 18th-century philosopher, speculated that if a blind person developed vision, he would not at first connect his idea of a shape with the sight of a shape. That is, if asked which was the cube and which was the sphere, he would not be able to do so, or even guess.

The question was originally posed to him by philosopher William Molyneux, whose wife was blind:[2]

Suppose a man born blind, and now adult, and taught by his touch to distinguish between a cube and a sphere of the same metal, and nighly of the same bigness, so as to tell, when he felt one and the other, which is the cube, which is the sphere. Suppose then the cube and the sphere placed on a table, and the blind man made to see: query, Whether by his sight, before he touched them, he could now distinguish and tell which is the globe, which the cube? To which the acute and judicious proposer answers: 'Not. For though he has obtained the experience of how a globe, and how a cube, affects his touch; yet he has not yet attained the experience, that what affects his touch so or so, must affect his sight so or so...'

In 1709, in A New Theory of Vision, George Berkeley also concluded that there was no necessary connection between a tactile world and a sight worldthat a connection between them could be established only on the basis of experience.He speculated:

the objects to which he had hitherto used to apply the terms up and down, high and low, were such as only affected or were in some way perceived by touch; but the proper objects of vision make a new set of ideas, perfectly distinct and different from the former, and which can in no sort make themselves perceived by touch (sect. 95).

This thought experiment (it was a thought experiment at the time) outlines the debate between rationalism and empiricism; to what degree our knowledge of the world comes from reason or experience.

There are many stories or anecdotes of the phenomenon, preceding the first documented case, including one from the year 1020, of a man of thirty operated upon in Arabia.[3]

Before the first known human cases, some tests were done rearing animals in darkness, to deny them vision for months or years, then discover what they see when given light. A. H. Reisen found severe behavioural losses in such experiments; but they might have been due to degeneration of the retina.[4]

The first known case of published recovery from blindness is often stated to be that described in a 1728 report of a blind 13-year-old boy operated by William Cheselden.[5] Cheselden presented the celebrated case of the boy of thirteen who was supposed to have gained his sight after couching of congenital cataracts.In 2021, the name of Cheselden's patient was reported for the first time: Daniel Dolins.[1] As it happens, philosopher George Berkeley knew the Dolins family, had numerous social links to Cheselden, including the poet Alexander Pope, and Princess Caroline, to whom Cheselden's patient was presented.[1] The report misspelled Cheselden's name, used language typical of Berkeley, and may even have been ghost-written by Berkeley.[1] Despite his youth, the boy encountered profound difficulties with the simplest visual perceptions.Described by "Chesselden":

When he first saw, he was so far from making any judgment of distances, that he thought all object whatever touched his eyes (as he expressed it) as what he felt did his skin, and thought no object so agreeable as those which were smooth and regular, though he could form no judgment of their shape, or guess what it was in any object that was pleasing to him: he knew not the shape of anything, nor any one thing from another, however different in shape or magnitude; but upon being told what things were, whose form he knew before from feeling, he would carefully observe, that he might know them again;[6]

Unfortunately, Dolins was never able to see well enough to read, and there is no evidence that the surgery improved Dolins' vision at any point prior to his death at age 30.[1] A total of 66 early cases of patients who underwent cataract operations were reviewed by Marius von Senden in his German 1932 book, which was later translated into English under the title Space and sight.[7] In this book, von Senden argues that shapes, sizes, lengths and distances are difficult for blind people to judge, including for a time after their operation.

In his book, An Anthropologist On Mars (1995), neurologist Oliver Sacks recounts the story of Virgil, a man who saw very little until having cataract surgery at age 50. Virgil's subsequent behavior was that of a "mentally blind" personsomeone who sees but cannot decipher what is out there; he would act as if he were still blind. Often confused, Virgil rapidly sank into depression.[8]

In 1974, Richard Gregory described a patient, Sidney Bradford, a 52-year-old who gained vision from corneal grafts to both eyes. No experimental psychologist was informed of the case until after the corneal grafting took place.His operation was able to reveal idiosyncrasies of the human visual system. For example, not having grown up with vision, Bradford did not perceive the ambiguity of the Necker cube. Nor was he able to interpret the perspective of two-dimensional art.

Nevertheless, he could accurately judge the distance to objects in the same room, having been familiar with these distances before regaining sight by virtue of having walked them. In a similar analogy between vision and sightless (touch-only) experience, Bradford was able to visually read the time on the ward clock just after his operation. Before surgery Bradford was a machinist, but even after acquiring vision preferred working with his eyes closed to identify tools. He died two years after his operation due to a prolonged period of ill health, with no specific cause of death noted.[9][10][11]

Michael G. "Mike" May (born 1954) was blinded by a chemical explosion at the age of 3 but regained partial vision in 2000, at 46, after corneal transplantation and a pioneering stem cell procedure by San Francisco ophthalmologist Daniel Goodman.[12]May had a stem-cell transplant in his right eye in 2001 when he was 47, after 40 years of blindness. He reportedly has adapted well to his recovered vision.

The effect of visual loss has an impact in the development of the visual cortex of the brain. The visual impairment causes the occipital lobe to lose its sensitivity in perceiving spatial processing. Sui and Morley (2008) proposed that after seven days of visual deprivation, a potential decrease in vision may occur. They also found an increasing visual impairment with deprivation after 30 days and 120 days. This study suggests that the function of the brain depends on visual input. May lost his eyesight at age three, when his vision was still not fully developed to distinguish shapes, drawings or images clearly. It would be difficult for him to be able to describe the world compared to a normal sighted person. For instance, May would have trouble differentiating complex shapes, dimension and orientations of objects. Hannan (2006) hypothesized that the temporal visual cortex uses prior memory and experiences to make sense of shapes, colours and forms. She proposed that the long-term effect of blindness in the visual cortex is the lack of recognition of spatial cues.

At three years of age, May's vision had still not reached the acuity of an adult person, so his brain was still not completely exposed to all possible clarity of images and light of the environment. This made it difficult for Michael to lead a normal daily life. Cohen et al. (1997) suggested that early blindness causes a poor development of the visual cortex with the result of a decrease in somatosensory development. This study proposed that Michael's long-term blindness affects his ability to distinguish in between faces of males and females, and to recognize pictures and images. In spite of the surgery on his right eye, his newly regained vision, after blindness of forty years, is not fully recovered. Thinus-Blanc and Gaunet (1997) suggest that early blinded people show limited ability in spatial representation. Michael still struggles to identify pictures or illustrations. The impairment of his visual cortex, due to the loss of his vision at a very early age, resulted in visual cortex cells that are not used to the stimuli in his surroundings. Cohen et al. (1997) proposed that in their early age, blinded subjects developed strong motivations to tactile discrimination tasks. May's early blindness benefited him so far; he developed very precise senses of hearing and touch.

In 2006, journalist Robert Kurson wrote a book on May, Crashing Through, expanded from an article he did for Esquire,[13] which was adapted into a motion picture.[14] Crashing Through was released on May 15, 2007.

Shirl Jennings (19402003) was blinded by illness as a young boy. Experimental surgery in 1991 partially restored his vision, but like Bradford and May, Jennings found the transition to sightedness difficult. In 1992, a pneumonia infection resulted in anoxia, and ultimately cost Jennings his vision again.

In 2011, The Guardian published a story about Shander Herian, who was blinded by illness at the age of 14 and fully recovered after an experimental surgery in middle age.[15]

More recently, another condition called aniridia has been treated with reconstructive surgery using the membrane from the amniotic sac that surrounds a fetus combined with stem cell transplantation into the eye.[16]In 2003, three people were successfully implanted with a permanent "retinal prosthesis" by researchers at the University of Southern California. Each patient wore spectacles with miniature video cameras that transmitted signals to a 4-mm-by-5-mm retinal implant via a wireless receiver embedded behind the ear.[17]

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Colour blindness tests, juggling, avoiding glare: A hockey goalkeepeers quest to train his biggest weapon, eyes – The Indian Express

January 23rd, 2023 12:05 am

Colour blindness tests, juggling, avoiding glare: A hockey goalkeepeers quest to train his biggest weapon, eyes  The Indian Express

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