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Monthly information related to total number of voting rights and shares composing the share capital _May 15, 2023
Daix (France), Long Island City (New York, United States), May 16, 2023 – Inventiva (Euronext Paris and Nasdaq: IVA) (the “Company”), a clinical-stage biopharmaceutical company focused on the development of oral small molecule therapies for the treatment of patients with non-alcoholic steatohepatitis (“NASH”) and other diseases with significant unmet medical needs, today reported financial information for the first quarter of 2023, including its cash, cash equivalents and revenues, and provided a corporate update.
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Inventiva reports 2023 First Quarter Financial Information¹ and provides a corporate update
BRISBANE, Calif., May 16, 2023 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a clinical-stage biopharmaceutical company developing a new class of complement medicines for patients with classical complement-mediated autoimmune, neurodegenerative and ophthalmic disorders, today announced that it has granted equity inducement awards to two new non-executive employees under the terms of the 2022 Employment Inducement Award Plan. The equity awards were approved on May 15, 2023, in accordance with Nasdaq Listing Rule 5635(c)(4).
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Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)
VANCOUVER, British Columbia, May 16, 2023 (GLOBE NEWSWIRE) -- Mydecine Innovations Group (NEO: MYCO) (OTC: MYCOF) (FSE: 0NFA) ("Mydecine" or the "Company"), a biotechnology company engineering the next wave of innovative medications and treatment protocols to directly address mental health with a particular emphasis on addiction and PTSD, announces the financial results for the three months ended March 31, 2023.
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Mydecine Reports Financial Results for the First Quarter of Fiscal Year 2023
~60% reduction in annualized infection rate seen in the mavorixafor arm vs. placebo (p<0.01)
Call scheduled for Thursday, June 22nd at 4:30 pm Eastern Time Call scheduled for Thursday, June 22nd at 4:30 pm Eastern Time
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Beyond Air® Schedules Fiscal Year End 2023 Financial Results Conference Call and Webcast
CARSON CITY, Nev., May 16, 2023 (GLOBE NEWSWIRE) -- BioVie Inc., (NASDAQ: BIVI) (“BioVie” or the “Company”) a clinical-stage company developing innovative drug therapies for the treatment of neurological and neurodegenerative disorders and advanced liver disease, today announced that a poster detailing the supporting data and rationale for a potentially pivotal clinical trial of NE3107 in the treatment of Parkison’s Disease was presented at the 2023 World Congress on Parkison’s Disease and Related Disorders (IAPRD), held in Chicago, IL May 13-16, 2023.
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BioVie Presents Rationale for Potentially Pivotal Trial of NE3107 in the Treatment of Parkinson’s Disease at 2023 International Association of...
DURHAM, N.C., May 16, 2023 (GLOBE NEWSWIRE) -- Bioventus Inc. (Nasdaq: BVS) ("Bioventus" or "the Company"), a global leader in innovations for active healing, today reported financial results for the three months ended April 1, 2023.
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Bioventus Reports First Quarter Financial Results
Michelle Robertson to remain with Company until August 16, 2023 Michelle Robertson to remain with Company until August 16, 2023
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Editas Medicine Announces Appointment of Erick J. Lucera as Chief Financial Officer
Company on track to complete planned interim analyses from two ongoing Phase 2 studies of the OCA-bezafibrate combination in 2023
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IBT resolves on a rights issue
Infant Bacterial Therapeutics AB (publ), Reg. No. 556873-8586, with its registered office in Stockholm, gives notice of the Extraordinary General Meeting to be held on Friday June 9, 2023 at 10.00 CEST in the premises of the company at Bryggargatan 10, Stockholm.
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Notice of Extraordinary General Meeting of Infant Bacterial Therapeutics
CAMBRIDGE, Mass. and ROSTOCK, Germany and BERLIN, May 16, 2023 (GLOBE NEWSWIRE) -- Centogene N.V. (Nasdaq: CNTG) (“we” or the “Company”), the essential life science partner for data-driven answers in rare and neurodegenerative diseases, today announced financial results for the fiscal year ended December 31, 2022, and provided a business update.
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CENTOGENE Reports Full Year 2022 Financial Results
SOUTH SAN FRANCISCO, Calif., May 16, 2023 (GLOBE NEWSWIRE) -- Akero Therapeutics, Inc. (Nasdaq: AKRO), a clinical-stage company developing transformational treatments for patients with serious metabolic disease marked by high unmet medical need, today announced the pricing of an underwritten offering of 5,238,500 shares of its common stock at a price of $42.00 per share, before deducting underwriting discounts and commissions, for total gross proceeds of approximately $220.0 million. All of the shares to be sold in the offering are being sold by Akero Therapeutics. The financing was led by new investor General Atlantic and included existing investors Adage Capital Partners LP, Avidity Partners, Boxer Capital, Commodore Capital, Janus Henderson Investors, Logos Capital, Perceptive Advisors, Rock Springs Capital and funds and accounts advised by T. Rowe Price Associates, Inc. The offering is expected to close on or about May 19, 2023, subject to the satisfaction of customary closing conditions.
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Akero Therapeutics Announces Pricing of $220.0 Million Underwritten Offering of Common Stock
Stay on top of your fur baby's health: the importance of scheduling routine vet visits FoxReno.com
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Stay on top of your fur baby's health: the importance of scheduling routine vet visits - FoxReno.com
The Rocky Mountain States, for example, have a lower prevalence of cancer death compared to the Gulf States, says Chrysohoou yet the background radiation in Idaho, Colorado and New Mexico is around three times as high as the natural background radiation in Louisiana, Mississippi and Alabama. A few animal studies have also found that a very low dose of radiation can induce an anti-inflammatory response and DNA repair possibly in the same way that the small but beneficial stress of caloric restriction can trigger protective mechanisms within cells.
For the time being, the finding remains a curiosity. Many more studies would have to confirm that these patterns cannot be explained by other factors and their potential mechanisms; Chrysohoou certainly isnt suggesting that radioactive drinks might be the elusive elixir of youth. It is rather dangerous to expect that radioactivity is good for your health, she admits.
The moderation principle
Clearly, exceptional longevity of the Blue Zones cant be restricted to a single magic ingredient, but is the combination of many factors some of which are shared between the regions, and some of which are unique to each individual place. While that may not be as enticing as the discovery of a miraculous anti-ageing elixir or superfood, there are nevertheless many ways we could learn from these discoveries.
Eating moderately with plenty of fruit and vegetables, exercising plenty, drinking coffee and tea, and finding space for spiritual solace (whether thats church or a long mountain walk) these are things that we can all build into our daily lives.
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* David Robson is the author of The Intelligence Trap, which examines why smart people act foolishly and the ways we can all make wiser decisions. He is @d_a_robson on Twitter.
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The ingredients for a longer life - BBC Future
The chorus of the theme song for the movie Fame, performed by actress Irene Cara, includes the line Im gonna live forever. Cara was, of course, singing about the posthumous longevity that fame can confer. But a literal expression of this hubris resonates in some corners of the worldespecially in the technology industry. In Silicon Valley, immortality is sometimes elevated to the status of a corporeal goal. Plenty of big names in big tech have sunk funding into ventures to solve the problem of death as if it were just an upgrade to your smartphones operating system.
Yet what if death simply cannot be hacked and longevity will always have a ceiling, no matter what we do? Researchers have now taken on the question of how long we can live if, by some combination of serendipity and genetics, we do not die from cancer, heart disease or getting hit by a bus. They report that when omitting things that usually kill us, our bodys capacity to restore equilibrium to its myriad structural and metabolic systems after disruptions still fades with time. And even if we make it through life with few stressors, this incremental decline sets the maximum life span for humans at somewhere between 120 and 150 years. In the end, if the obvious hazards do not take our lives, this fundamental loss of resilience will do so, the researchers conclude in findings published in May 2021 in Nature Communications.
They are asking the question of Whats the longest life that could be lived by a human complex system if everything else went really well, and its in a stressor-free environment? says Heather Whitson, director of the Duke University Center for the Study of Aging and Human Development, who was not involved in the paper. The teams results point to an underlying pace of aging that sets the limits on life span, she says.
For the study, Timothy Pyrkov, a researcher at a Singapore-based company called Gero, and his colleagues looked at this pace of aging in three large cohorts in the U.S., the U.K. and Russia. To evaluate deviations from stable health, they assessed changes in blood cell counts and the daily number of steps taken and analyzed them by age groups.
For both blood cell and step counts, the pattern was the same: as age increased, some factor beyond disease drove a predictable and incremental decline in the bodys ability to return blood cells or gait to a stable level after a disruption. When Pyrkov and his colleagues in Moscow and Buffalo, N.Y., used this predictable pace of decline to determine when resilience would disappear entirely, leading to death, they found a range of 120 to 150 years. (In 1997 Jeanne Calment, the oldest person on record to have ever lived, died in France at the age of 122.)
The researchers also found that with age, the bodys response to insults could increasingly range far from a stable normal, requiring more time for recovery. Whitson says that this result makes sense: A healthy young person can produce a rapid physiological response to adjust to fluctuations and restore a personal norm. But in an older person, she says, everything is just a little bit dampened, a little slower to respond, and you can get overshoots, such as when an illness brings on big swings in blood pressure.
Measurements such as blood pressure and blood cell counts have a known healthy range, however, Whitson points out, whereas step counts are highly personal. The fact that Pyrkov and his colleagues chose a variable that is so different from blood counts and still discovered the same decline over time may suggest a real pace-of-aging factor in play across different domains.
Study co-author Peter Fedichev, who trained as a physicist and co-founded Gero, says that although most biologists would view blood cell counts and step counts as pretty different, the fact that both sources paint exactly the same future suggests that this pace-of-aging component is real.
The authors pointed to social factors that reflect the findings. We observed a steep turn at about the age of 35 to 40 years that was quite surprising, Pyrkov says. For example, he notes, this period is often a time when an athletes sports career ends, an indication that something in physiology may really be changing at this age.
The desire to unlock the secrets of immortality has likely been around as long as humans awareness of death. But a long life span is not the same as a long health span, says S. Jay Olshansky, a professor of epidemiology and biostatistics at the University of Illinois at Chicago, who was not involved in the work. The focus shouldnt be on living longer but on living healthier longer, he says.
Death is not the only thing that matters, Whitson says. Other things, like quality of life, start mattering more and more as people experience the loss of them. The death modeled in this study, she says, is the ultimate lingering death. And the question is: Can we extend life without also extending the proportion of time that people go through a frail state?
The researchers final conclusion is interesting to see, Olshansky says. He characterizes it as Hey, guess what? Treating diseases in the long run is not going to have the effect that you might want it to have. These fundamental biological processes of aging are going to continue.
The idea of slowing down the aging process has drawn attention, not just from Silicon Valley types who dream about uploading their memories to computers but also from a cadre of researchers who view such interventions as a means to compress morbidityto diminish illness and infirmity at the end of life to extend health span. The question of whether this will have any impact on the fundamental upper limits identified in the Nature Communications paper remains highly speculative. But some studies are being launchedtesting the diabetes drug metformin, for examplewith the goal of attenuating hallmark indicators of aging.
In this same vein, Fedichev and his team are not discouraged by their estimates of maximum human life span. His view is that their research marks the beginning of a longer journey. Measuring something is the first step before producing an intervention, Fedichev says. As he puts it, the next steps, now that the team has measured this independent pace of aging, will be to find ways to intercept the loss of resilience.
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Humans Could Live up to 150 Years, New Research Suggests
Life expectancy is the statistical measure of the average time a person is expected to live. According to the World Health Organization (WHO), the global life expectancy as of 2016 was 72.0 years, 74.2 for females and 69.8 years for men. The average life expectancy at birth for the U.S. varies depending on the source. The latest figures are: 78.5 years, according to the OECD; 78.6 years, according to the CDC; 80.0 years, according to the CIA.
In general, life expectancy is based on two major factors: genetics and lifestyle choices. These include, but are not limited to: gender, access to quality health care, hygine, obesity, diet and nutrition, exercise, and crime rates. Overall, you can expect to see the highest life expectancies in the healthiest states. Additionally, women tend to live longer than men. American men expect to live an average of 76.1 years, while women expect to live an average of 81.1 years, a five-year difference.
Because the above factors vary greatly by state, so do life expectancies. On average, Hawaii residents live longer than residents in any other state, about 81.5 years, while Mississippi residents live the shortest lives at 74.6 years. This is a difference of 6.9 years. In general, the South has lower life expectancies than other parts of the country.
The ten states with the longest life expectancies, in order, are: Hawaii (81.5), California (80.8), Minnesota (80.8), New York (80.7), Connecticut (80.6), New Jersey (80.4), Colorado (80.0), Washington (80.0), Massachusetts (79.0), and Vermont (79.0). Hawaii has the longest life expectancy in the United States at 81.5 years. Women in Hawaii are the longest-living Americans at 84.3 years. If Hawaii were a country, it would have the 21st-highest longevity globally. Physical activity is high in the state, and its 25% obesity rate is the third-lowest nationwide. Low obesity rates are common in this list, with eight of the ten states having obesity rates at 28.3% or lower. Colorado has the lowest at 23.8%.
The ten states with the lowest life expectancies, in order, are: Mississippi (74.6), West Virginia (74.9), Alabama (74.9), Kentucky (75.1), Arkansas (75.4), Oklahoma (75.5), Louisiana (75.5), Tennessee (76.1), South Carolina (76.2), and Ohio (76.6). Mississippi's longevity is the lowest in the United States at 74.6 years. Mississippi men live the shortest lives on average of 71.4 years. Mississippi is the most obese state, with 40.8% of adults being obese. Unsurprisingly, nine of the ten most obese states are also on the list of the ten states with the shortest life spans. In general, Louisiana, Mississippi, Alabama, Oklahoma, and Arkansas are considered the least-healthy states, with high rates of obesity, excessive drinking, cancer, and heart disease, and low-quality health care.
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Life Expectancy by State 2023 - World Population Review
We the Founders and leadership of Fountain Life seek to build a global company delivering the most advanced diagnostics and vetted therapeutics to those who seek a longer, healthier and more vital life.
We seek to extend member healthspan by using a foundation of functional medicine-based protocols plus an annual 150 Gb Upload of imaging, genetic and blood-related diagnostics. Our goal is to reliably predict future disease, and to detect any such disease at the earliest moment possible, thereby stopping and ultimately reversing its progression, returning our member to peak performance.
Fountain and its network of physicians and scientists are constantly scanning the world searching for low-risk, high-reward therapeutic treatments. Once vetted, those treatments with the greatest promise are made available to all members through our Centers. Fountain requires that treatments delivered to its members are either FDA approved, or delivered under an approved investigational protocol.
Fountain believes that there is no substitution for a brilliant and thoughtful medical team delivering healthcare services. As such, we have developed an innovative care model, utilizing a vertically integrated, 6-person healthcare team. Each Fountain Member is supported by a Concierge Physician, Nurse Practitioner, and a group of four health care coordinators and coaches. These teams are trained to the highest standards at Fountain University in accordance with A4M, the Functional Medical Institute and other cutting edge partnerships.
Finally, Fountain also is making use of the most advanced artificial intelligence technologies available in order to enable a smooth and seamless member experience, while at the same time mining our vast data-set to glean personalized insights capable of bestowing lifesaving consequences.
In Health,Fountain Lifes Founders & Leadership
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About Us - Fountain Life
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May is Melanoma and Skin Cancer Awareness Month. Keep up with the latest news on skin in the Dermatology channel - Newswise