StemCell Therapy

New Jersey, United States:The Veterinary Medicine Market is carefully researched in the report while largely concentrating on top players and their business tactics, geographical expansion, market segments, competitive landscape, manufacturing, and pricing and cost structures. Each section of the research study is specially prepared to explore key aspects of the Veterinary Medicine market. For instance, the market dynamics section digs deep into the drivers, restraints, trends, and opportunities of the Veterinary Medicine Market. With qualitative and quantitative analysis, we help you with thorough and comprehensive research on the Veterinary Medicine market. We have also focused on SWOT, PESTLE, and Porters Five Forces analyses of the Veterinary Medicine market.

Leading players of the Veterinary Medicine market are analyzed taking into account their market share, recent developments, new product launches, partnerships, mergers or acquisitions, and markets served. We also provide an exhaustive analysis of their product portfolios to explore the products and applications they concentrate on when operating in the Veterinary Medicine market. Furthermore, the report offers two separate market forecasts one for the production side and another for the consumption side of the Veterinary Medicine market. It also provides useful recommendations for new as well as established players of the Veterinary Medicine market.

Veterinary Medicine Market by Regional Segments:

The chapter on regional segmentation describes the regional aspects of the Veterinary Medicine market. This chapter explains the regulatory framework that is expected to affect the entire market. It illuminates the political scenario of the market and anticipates its impact on the market for Veterinary Medicine.

Analysts who have authored the report have segmented the market for Veterinary Medicine by product, application and region. All segments are the subject of extensive research, with a focus on CAGR, market size, growth potential, market share and other important factors. The segment study provided in the report will help players focus on the lucrative areas of the Veterinary Medicine market. The regional analysis will help the actors to strengthen their position in the most important regional markets. It shows unused growth opportunities in regional markets and how they can be used in the forecast period.

Ask for Discount @ https://www.verifiedmarketresearch.com/ask-for-discount/?rid=21894&utm_source=SGN&utm_medium=003

Highlights of TOC:

Overview: In addition to an overview of the Veterinary Medicine market, this section provides an overview of the report to give an idea of the type and content of the study.

Market dynamics: Here the authors of the report discussed in detail the main drivers, restrictions, challenges, trends and opportunities in the market for Veterinary Medicine.

Product Segments: This part of the report shows the growth of the market for various types of products sold by the largest companies.

Application segments: The analysts who have authored the report have thoroughly evaluated the market potential of the key applications and identified the future opportunities they should create in the Veterinary Medicine.

Geographic Segments: Each regional market is carefully examined to understand its current and future growth scenarios.

Company Profiles: The top players in the Veterinary Medicine market are detailed in the report based on their market share, served market, products, applications, regional growth and other factors.

The report also includes specific sections on production and consumption analysis, key results, key suggestions and recommendations, and other issues. Overall, it offers a complete analysis and research study of the Veterinary Medicine market to help players ensure strong growth in the coming years.

Complete Report is Available @ https://www.verifiedmarketresearch.com/product/Veterinary-Medicine-Market/?utm_source=SGN&utm_medium=003

About us:

Verified market research partners with the customer and offer an insight into strategic and growth analyzes; Data necessary to achieve corporate goals and objectives. Our core values are trust, integrity and authenticity for our customers.

Analysts with a high level of expertise in data collection and governance use industrial techniques to collect and analyze data in all phases. Our analysts are trained to combine modern data collection techniques, superior research methodology, expertise and years of collective experience to produce informative and accurate research reports.

Contact us:

Mr. Edwyne FernandesCall: +1 (650) 781 4080Email: [emailprotected]

Tags: Veterinary Medicine Market Size, Veterinary Medicine Market Trends, Veterinary Medicine Market Forecast, Veterinary Medicine Market Growth, Veterinary Medicine Market Analysis

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Veterinary Medicine Market 2020 | Growing Rapidly with Significant CAGR, Leading Players, Innovative Trends and Expected Revenue by 2026 - Skyline...

DEAR ABBY: My husband barely speaks to me. We both work full time and are facing the empty nest very soon. At home, I have to initiate even the smallest of small talk. He'll never say "Good morning" or ask "How was your day?" Although I work hard to keep the house the way he likes it, he speaks up only to criticize the few times I don't meet his standards. There's never a word of acknowledgment when I have accomplished other elements of housekeeping.

When I laugh at the Sunday comics, he doesn't even ask what's funny. As a result, I have become defensive. Then he accuses me of being "dismissive of his feelings." He says I don't communicate with him, but when I do, he barely responds, so over the years I have basically shut down. We have been to counseling, and maybe it's time to go again. Do you have any perspective to offer?

UNACKNOWLEDGED IN THE SOUTH

DEAR UNACKNOWLEDGED: It is definitely the right move to return to counseling. But when you do, this time speak up for yourself loud and clear. If you do, it may change the dynamics of your relationship because when he accuses you of not communicating, he is blaming the victim. Once you have said your piece, let the marriage and family therapist mediate what is certain to be a long-overdue discussion.

DEAR ABBY: I am a 25-year-old man currently dating a 39-year-old woman. We have been dating for 2 1/2 months. We have talked about our age difference a couple of times, but apart from that issue, every other aspect of our relationship is going well, including communication, intimacy and maturity.

We are not super interested in having children, and we both have expressed interest in adopting a child if we were to have one somewhere down the line. Despite this, I have heard from family (my parents, mostly) and close friends that I'm making a terrible mistake by dating a woman so much older.

They say it is not practical to marry a woman so much older because it will present major health and aging challenges as time goes by. This is the argument that most influences my feelings. Should I break up with her and tell her that the age difference is the reason? I feel I should decide soon so as not to waste her time.

NOT JUST A NUMBER IN SAN FRANCISCO

DEAR NOT JUST A NUMBER: You have been seeing this woman for only 2 1/2 months. The relationship is still new. That you are discussing marriage and children seems to me to be premature. My advice is to slow down. Let time dictate whether this romance develops further.

Discuss the flak you are getting from your parents with your lady friend. But the 14-year age difference does not necessarily mean that she'll have health challenges that you won't. Decide together whether the age difference is a deal-breaker.

DEAR ABBY: This may seem like a strange question, but my husband says our 6-year-old cat, "Taffy," is really 42 years old. He says one cat year equals seven people years. Taffy is like a baby to me. What gives?

NEVER HEARD THAT IN NEVADA

DEAR NEVER HEARD: Your husband is right. As you may have already noticed, humans have longer lives than dogs and cats, but pets mature faster. According to veterinary medicine, the first two years of a cat's life equal 25 human years. After that, every cat year equals four human years. This would make Taffy the ripe old age of 41 or 42. If this is shocking to you, remember that 42 is the new 22.

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Marriage crumbling as couple's communication becomes bitter - News from southeastern Connecticut - theday.com

Ally the dachshund has chronic pancreatitis thatrequires daily care.

Its special veterinarian-assisted care that her owner is worried might not be available when she needs it most due to the ongoing COVID-19 outbreak.

Shes on strict food and thats the only thing shes allowed. Shes allowed no treats, no human food, no nothingand insulin twice a day, said Marisa Panter. She cant have a different kind of food, the food is bought from a vet office. She cant have a different kind of insulin, and the insulin is bought from a vet office.

Panter and 7-year-old Ally live outside of Kelowna, along with her three-year-old daughter, 13-year-old step-son, her husband, her in-laws, and six pregnant dachshunds that Panter is breeding.

Ally loves all dogs and humans she meets. Shes visited hospitals and retirement homes, bringing joy to residents and patients, and is inseparable from Panters daughter.

Shes probably done 500,000 km in a vehicle, if we go anywhere and were not going to be home for insulin, we have to take her with us, she said

Like most veterinarian clinics, Panters vet clinic has closed its doors to all non-essential visits and has resorted to parking lot pickups for food and medication.

She shares a common concern with many pet owners during this time will she be able to get the adequate care she needs when so many services are being cut back?

If her pancreatitis acts up, she needs to be in a (clinic) for three days on IV, she said. If theres no vets, I watch her die.

Dr. Chris Armstrong, a veterinarian and member of the Canadian Veterinary Medical Associations (CVMA) Council, said the one of the main things pet owners should keep in mind is that vet clinics have been declared essential in many provinces and theres no sign of them shutting down in British Columbia.

READ MORE: B.C. vet stresses need for pet hygiene despite COVID-19 risk being low

READ MORE: More information needed after dogs weak positive COVID-19 test result: expert

It may not be business as usual, but I think certainly pet owners and animal owners should not be afraid that their animals wont be taken care of, she said. Particularly in emergency or urgent situations.

Virtual care options are also starting to become available GoFetch Health recently launched a Canada-wide service that can help pet owners connect with vets to ask questions and get advice on if their animal needs further care.

The CVMA put out a statement on March 24 advising vets on best practices for telemedicine. However, Armstrong said there is a big worry in her industry: running out of medical supplies.

Veterinarians, like human medicine, were running out of masks, were running out of surgical gloves, were running out of personal protection equipment, she said.

Armstrong said that puts limits on things like non-essential surgeries, like a neutering or spaying.

I think thats really one of the biggest limiting factors is: can we access sufficient masks and gloves and gowns to be able to continue service?

When it comes to another common worry, running out of medicine, Armstrong said that hasnt been a problem so far. She urges pet owners to resist hoarding because that would start to affect supply.

For most of the medications, I think certainly the supply chain is still there, she said. Hoarding at least for pet owners goes just as true for medications and products.

Armstrong said people have also been worried about their pets contracting COVID, which she said is very unlikely. Theres also been no proof that humans can contract COVID from their pets.

There has only been two COVID positive dogs, theres been a tremendous number of dogs been tested through IDEX, which is one of our labs, she said. And out of all the testing, its only the two Hong Kong dogs.

However, Armstrong said its worth remembering that pets can carry COVID, much like any other surface.

Dogs, like your pen or a table, could act as what we call a fomite, she said. So, in other words, a COVID positive person kissed their dog on the head, just like if they kissed their pen, could they put the virus on those two objects? And the answer is, yes.

New information comes forward all the time, said Armstrong, and the best thing pet owners can do is stay up to date from reliable sources.

I think that the message to go across is that, if we are patient, if we kind of know that this is a fluid situation, take direction from responsible and reliable sources, she said.

Stay calm and be nice.

cloe.logan@pqbnews.com

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AnimalsCoronavirus

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B.C. veterinarians want to smooth the fur of COVID-19-worried pet owners - Coast Mountain News

Horse racing at Golden Gate Fields, Albany, California. Photo: Noah Salzman CC BY-SA 4.0, via Wikimedia Commons

A major US study will explore the effects of a combination of two drugs that may be contributing to catastrophic injuries and cardiac issues in racehorses.

Researchers at the University of Pennsylvanias New Bolton Center, part of the School of Veterinary Medicine, will carry out a multidisciplinary study exploring combined usage of furosemide, commonly known as Lasix, and bisphosphonates in horses.

It will be the first comprehensive analysis of the two drugs that, when used concurrently could be capable of diminishing bone integrity and compromising cardiac function in racehorses. These effects have the potential to contribute to catastrophic injuries on the racetrack.

The beauty of this study is that it will use a multi-disciplinary approach to assess the interaction between these two drugs that we know are administered to racehorses, says Dr Mary Robinson, assistant professor of veterinary pharmacology and director of the Equine Pharmacology Laboratory at the New Bolton Center.

By coupling our state-of-the-art imaging technologies with the scope of expertise among the other investigators on this project, we will be able to produce solid, unbiased data that will address some of the unknowns surrounding the use of these medications.

Nearly 85 percent of racehorses in the United States receive Lasix as a preventive therapy for a condition called exercise-induced pulmonary hemorrhage (EPIH), or bleeding into the lungs.

Also used in human medicine to treat heart conditions, the drug is known to cause a short-term loss of calcium and increase the risk of fractures in human patients.

But because horses can quickly recover from a calcium deficit, Lasix alone is unlikely to be the root cause for catastrophic, racing-related breakdowns which, according to The Jockey Club Equine Injury Database, occur at a rate of about 1.6 per 1000 starts.

A team comprised of 13 researchers from the vet school will explore the largely unknown effects of a class of drugs called bisphosphonates, particularly when being used with Lasix.

Intended to preserve the integrity of bone, bisphosphonates are commonly used in elderly patients to treat osteoporosis. When administered to young, growing animals, however, the drug may have adverse effects by preventing bone from properly adapting to the forces applied during training such as those experienced when a horse is at a gallop.

Because bisphosphonates can linger in the bone for at least one year after the administration of a single dose, there is a heightened chance for interaction with Lasix in horses who are undergoing training.

Bisphosphonates have also been associated with increased risks of heart conditions in humans, including atrial fibrillation, ventricular arrhythmias, and alterations in heart rate variability.

The research team will cross-examine other facets related to the use of these substances in racehorses, including pioneering new understandings of advanced imaging systems such as New Bolton Centers standing robotic computed tomography (CT) and, in collaboration with Dr Mathieu Spriet, from the University of California, Davis, a new standing positron emission tomography (PET) system.

The system, which is identical to the one already in place at Santa Anita Park, will make the New Bolton Center the second veterinary hospital in the world to implement the use of an equine PET scanner.

This amazing imaging technology is going to be really instrumental in helping us assess the effects or lack thereof of these drugs on the bone, Robinson says.

It is the most sensitive technique that we have, from an imaging perspective, to look in detail at a horses legs and see whats going on metabolically.

The New Bolton Centers Kathryn Wulster says the technology will enable researchers to definitively note any changes in bone turnover in areas as precise as two square millimeters.

But the real beauty of using both the PET scan and our robotic CT system in tandem is that we can confidently identify any present morphologic or shape abnormalities within the bone that we know could predispose a horse to fracture, Wulster says.

Together, theyre going to give us a remarkable amount of information about what is or isnt going on in these horses.

The research team will also be accumulating findings into an innovative, data-driven platform that will be invaluable to objectively assess national trends in racehorse related injuries.

Researchers at the vet school will also explore Extracellular Vesicle Cores (EVs) in blood or other samples to detect illicit use of bisphosphonates, which are presently undetectable in the blood of a horse after 30 days.

EVs are membrane-enclosed nanoparticles released from all cell types and play an integral role in intercellular communication. Because they possess tissue-specific characteristics representative of the cells in which they came from, they hold the potential to provide non-invasive, rapid diagnostic solutions to test for the presence of illegitimate drug use.

Dr Andrew Hoffman, dean of Veterinary Medicine and principal investigator of the EV Core Facility, describes the field of EV research as a vastly promising and explosive area of study.

By harnessing the unique communicative power of EVs, we hope to redefine how we can utilize blood samples in order to proactively safeguard the health and well-being of these tremendous athletes, he says.

Beyond detecting illegitimate substance use, these biomarkers also offer the means of identifying otherwise indiscernible, but significant, changes in the horses biological health that could serve as warning signs of an increased risk for catastrophic injury.

Robinson adds: Our hope is to eventually harness the information carried in these vesicles to develop a hand-held, stall-side diagnostic tool that could be used on race day to make sure horses are healthy enough to compete safely, as well as by trainers in the field to continuously evaluate any changes in their horses well-being, and when additional veterinary care may be needed.

The study is expected to take two years to complete.

It will, says Robinson, provide the most comprehensive data available to assess if the use of these substances may or may not be contributing to catastrophic injuries on the track.

At the end of the day, were dedicated to ensuring we are doing everything in our power to provide owners, breeders, and trainers with sound, unbiased insights to keep their horses safe.

Robinson is an assistant professor of veterinary pharmacology and director of the Equine Pharmacology Laboratory at the University of Pennsylvania School of Veterinary Medicine.

Additional investigators on the study include Dr Kyla Ortved, Dr Cristobal Navas de Solis, Dr Claire Underwood, Dr Virginia Reef, Dr Darko Stefanovski, Dr Rachel Derita, Dr Joanne Haughan, Dr Youwen You, Dr Jinwen Chen and Dr Zibin Jiang, all with the universitys veterinary school.

This study is supported in part by Roy and Gretchen Jackson, George and Julia Strawbridge, and the Pennsylvania State Horse Racing Commission.

In other news, the board the Racing Medication and Testing Consortium (RMTC) has approved the funding of an unrelated study on bisphosphonates through its Tactical Research Grant Program. The research will be conducted at Cornell University under the direction of Dr Heidi Reesink.

This study is an important first step in answering questions about the prevalence and effect of bisphosphonates in the training and racing population, so that we can refine our strategies in protecting racehorse bone health, RMTC executive director Dr Mary Scollay says.

The RMTC consists of 23 racing industry stakeholders and organizations that represent Thoroughbred, Standardbred, American Quarter Horse and Arabian racing.

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Study to explore whether a drug combination is harming horse bone health - Horsetalk

SYDNEY, N.S.

Veterinary care is now being deemed an essential service in Nova Scotia during the COVID-19 pandemic

Chief medical officer of health, Dr. Robert Strang, has asked for the province's Health Protection Act to be amended to include veterinarians.

Veterinarians have been asking the province to ensure their clinics can stay open during the COVID-19 outbreak to deal with sick and injured animals.

When Nova Scotia declared a state of emergency in an effort to reduce the spread of the virus, veterinary medicine wasnt listed as an essential service.

Even before Premier Stephen McNeil announced the state of emergency, the Nova Scotia Veterinary Medical Association had directed the approximately 100 animal hospitals and clinics it represents including 13 in Cape Breton to take measures to prevent the spread of COVID-19.

The association says veterinarians in the province are trained in epidemiology and herd health, so they have been quick to implement protocols to reduce the spread of infection.

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Health Protection Act in Nova Scotia to be amended to include veterinary services - Cape Breton Post

According to Masud Soleimani, who recently came home from illegal detainment in US, the research is being carried out with the support of the Health Ministry in two Tehran-based hospitals of Shariati and Masih Daneshvari.

The news came as some local media had earlier quoted Soleimani as saying that a drug for the disease has been developed.

In an interview with Mehr News Agency on Saturday night, Soleimani dismissed the reports as inaccurate, noting that this is not a drug but a method that is still being worked on.

The results of the first phase of its clinical trial will be announced soon by the Health Ministry, he added.

According to the latest announcement on Saturday, the number of confirmed cases of the COVID-19 has hit 35,408 in the country. 11,679 patients have recovered so far while the virus has claims 2,517 lives.

MAH/ 4888035

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Iranian scientists working on stem cell therapy to treat Covid-19 patients - Mehr News Agency - English Version

LONDON--(BUSINESS WIRE)--The global autologous cell therapy market is poised to grow by USD 1.97 billion during 2020-2024, progressing at a CAGR of almost 22% during the forecast period. Request free sample pages

Read the 120-page report with TOC on "Autologous Cell Therapy Market Analysis Report by Therapy (Autologous stem cell therapy and Autologous cellular immunotherapies), Application (Oncology, Musculoskeletal disorders, and Dermatology), Geography (North America, APAC, Europe, South America, and MEA), and the Segment Forecasts, 2020-2024".

https://www.technavio.com/report/autologous-cell-therapy-market-industry-analysis

The market is driven by the increasing demand for effective drugs for cardiac and degenerative disorders. In addition, the limitations in traditional organ transplantations are fueling the demand for stem cell therapies. All these factors are anticipated to boost the growth of the autologous cell therapy market.

The demand for effective drugs for cardiac and degenerative disorders has been increasing across the world. In addition, the discovery of possible cardiac autologous cells has enabled vendors to develop novel drugs for the treatment of various cardiac diseases. For instance, Mesoblast is developing MPC-150-IM. It is a Phase III candidate for the treatment of advanced and end-stage chronic heart failure. Similarly, Shire has been developing autologous stem cell therapies for chronic myocardial ischemia. These products are expected to be launched during the forecast period and will have a positive impact on the growth of the global autologous cell therapy market.

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Major Five Autologous Cell Therapy Market Companies:

Bayer AG

Bayer AG operates its business through segments such as Pharmaceuticals, Crop Science, Consumer Health, and Animal Health. The company offers induced pluripotent stem cells. They are developed by reprogramming mature body cells to behave like embryonic stem cells that are injected to restore diseased tissue in patients.

Brainstorm Cell Therapeutics Inc.

Brainstorm Cell Therapeutics Inc. operates its business through an unified business segment. NurOwn is the key offering of the company. It is a cell therapy platform, which develops mesenchymal stem cells for the treatment of human diseases such as immune and inflammatory diseases.

Daiichi Sankyo Co. Ltd.

Daiichi Sankyo Co. Ltd. operates its business through segments such as Innovative Pharmaceuticals, Generic, Vaccine, and OTC Related. Heartcel is the key offering of the company. It is an immune-modulatory progenitor cell therapeutic agent, which is used for ischemic heart failure.

FUJIFILM Holdings Corp.

FUJIFILM Holdings Corp. operates its business through segments such as Imaging solutions, Healthcare and material solutions, and Document solutions. The company uses induced pluripotent stem cells to derive differentiated cells, which are used in researching various diseases and conditions.

Holostem Terapie Avanzate Srl

Holostem Terapie Avanzate Srl operates its business through an unified business segment. Holoclar is the key offering of the company. It is an advanced therapy medicinal product containing stem cells indicated to repair the cornea after injury.

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Autologous Cell Therapy Market Therapy Outlook (Revenue, USD Billion, 2020-2024)

Autologous Cell Therapy Market Application Outlook (Revenue, USD Billion, 2020-2024)

Autologous Cell Therapy Market Regional Outlook (Revenue, USD Billion, 2020-2024)

Technavios sample reports are free of charge and contain multiple sections of the report, such as the market size and forecast, drivers, challenges, trends, and more.

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Related Reports on Healthcare Include:

Global Cancer Stem Cell Therapeutics Market Global cancer stem cell therapy market by type (allogeneic stem cell transplant and autologous stem cell transplant) and geography (Asia, Europe, North America, and ROW).

Global Mantle Cell Lymphoma Therapeutics Market Global mantle cell lymphoma therapeutics market by product (combination therapy and monotherapy) and geography (Asia, Europe, North America, and ROW).

About Technavio

Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.

With over 500 specialized analysts, Technavios report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavios comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

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Global Autologous Cell Therapy Market 2020-2024 | Evolving Opportunities with Bayer AG and Brainstorm Cell Therapeutics Inc. | Technavio - Business...

It is a universally acknowledged fact that the majority of women refuse to age, the moment they reach the age of 40. The desire to turn back the clock is something that gets automatically etched on their minds, after hitting middle age. Making a wise choice from the wide range of anti-ageing solutions available for women can be a highly baffling affair, but understanding the skins needs is equally crucial.

So what exactly is ageing, that every person, especially women dread? It can be regarded as a complex process resulting in accrual changes in a persons body over. a period of time. Ageing occurs in fractions, because the stem cells which have the ability to renew themselves grow old as DNA gets damaged and changes occur in the overall physiology. As time passes by and people age, the majority of the cells present in their bodies get replaced and the ability of the body to produce more new cells gradually declines, Thus, anti-ageing retards the degeneration process of the body.

Post an anti-ageing fat stem cell treatment the skin shows prominent signs of turning softer while the body notices a remarkable surge of energy, resulting in improved sleeping and breathing patterns, controlled sugar levels, rebalanced hormones, increased metabolism, average weight loss and fading age spots. This all seems possible owing to the insertion of 30-50 million supercharged active stem cells.

Ageing is indeed complex, as its causes have not yet been completely understood. A big part of ageing occurs when the body is being attacked by inflammation and oxidative stress. Even though it is said that ageing is a natural process which is unavoidable, there is still scope to maintain health and stay young for both preventing age-related diseases and to enjoy the benefits of youth.

The desire to be younger is not exactly a new idea. The concept of anti-ageing has kept humankind occupied since ages, with the idea about staying healthy and fit with age and improving the quality of life. So with the rising evidence about the association of ageing diseases with adult stem cell exhaustion, it will not be surprising to witness an elevation of interest towards restoring the adult stem cell function to improve these conditions and to turn back the clock!

Read the rest here:
Reversing The Ageing Process With Stem Cell Therapy - Version Weekly

New Jersey, United States:The Stem Cell Therapy Market is carefully researched in the report while largely concentrating on top players and their business tactics, geographical expansion, market segments, competitive landscape, manufacturing, and pricing and cost structures. Each section of the research study is specially prepared to explore key aspects of the Stem Cell Therapy market. For instance, the market dynamics section digs deep into the drivers, restraints, trends, and opportunities of the Stem Cell Therapy Market. With qualitative and quantitative analysis, we help you with thorough and comprehensive research on the Stem Cell Therapy market. We have also focused on SWOT, PESTLE, and Porters Five Forces analyses of the Stem Cell Therapy market.

Global Stem Cell TherapyMarketwas valued at USD 86.62 million in 2016 and is projected to reach USD 221.03million by 2025, growing at a CAGR of 10.97% from 2017 to 2025.

Leading players of the Stem Cell Therapy market are analyzed taking into account their market share, recent developments, new product launches, partnerships, mergers or acquisitions, and markets served. We also provide an exhaustive analysis of their product portfolios to explore the products and applications they concentrate on when operating in the Stem Cell Therapy market. Furthermore, the report offers two separate market forecasts one for the production side and another for the consumption side of the Stem Cell Therapy market. It also provides useful recommendations for new as well as established players of the Stem Cell Therapy market.

Stem Cell Therapy Market by Regional Segments:

The chapter on regional segmentation describes the regional aspects of the Stem Cell Therapy market. This chapter explains the regulatory framework that is expected to affect the entire market. It illuminates the political scenario of the market and anticipates its impact on the market for Stem Cell Therapy.

Analysts who have authored the report have segmented the market for Stem Cell Therapy by product, application and region. All segments are the subject of extensive research, with a focus on CAGR, market size, growth potential, market share and other important factors. The segment study provided in the report will help players focus on the lucrative areas of the Stem Cell Therapy market. The regional analysis will help the actors to strengthen their position in the most important regional markets. It shows unused growth opportunities in regional markets and how they can be used in the forecast period.

Ask for Discount @ https://www.verifiedmarketresearch.com/ask-for-discount/?rid=24113&utm_source=SGN&utm_medium=003

Highlights of TOC:

Overview: In addition to an overview of the Stem Cell Therapy market, this section provides an overview of the report to give an idea of the type and content of the study.

Market dynamics: Here the authors of the report discussed in detail the main drivers, restrictions, challenges, trends and opportunities in the market for Stem Cell Therapy.

Product Segments: This part of the report shows the growth of the market for various types of products sold by the largest companies.

Application segments: The analysts who have authored the report have thoroughly evaluated the market potential of the key applications and identified the future opportunities they should create in the Stem Cell Therapy.

Geographic Segments: Each regional market is carefully examined to understand its current and future growth scenarios.

Company Profiles: The top players in the Stem Cell Therapy market are detailed in the report based on their market share, served market, products, applications, regional growth and other factors.

The report also includes specific sections on production and consumption analysis, key results, key suggestions and recommendations, and other issues. Overall, it offers a complete analysis and research study of the Stem Cell Therapy market to help players ensure strong growth in the coming years.

Complete Report is Available @ https://www.verifiedmarketresearch.com/product/Stem-Cell-Therapy-Market/?utm_source=SGN&utm_medium=003

About us:

Verified market research partners with the customer and offer an insight into strategic and growth analyzes; Data necessary to achieve corporate goals and objectives. Our core values are trust, integrity and authenticity for our customers.

Analysts with a high level of expertise in data collection and governance use industrial techniques to collect and analyze data in all phases. Our analysts are trained to combine modern data collection techniques, superior research methodology, expertise and years of collective experience to produce informative and accurate research reports.

Contact us:

Mr. Edwyne FernandesCall: +1 (650) 781 4080Email: [emailprotected]

Tags: Stem Cell Therapy Market Size, Stem Cell Therapy Market Trends, Stem Cell Therapy Market Forecast, Stem Cell Therapy Market Growth, Stem Cell Therapy Market Analysis

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Laser Pointer Market Size, Growth Analysis, Opportunities, Business Outlook and Forecast to 2026

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Stem Cell Therapy Market 2020 | Growing Rapidly with Significant CAGR, Leading Players, Innovative Trends and Expected Revenue by 2026 - Skyline...

The electronic newsletter I Love My Freedom on a regular basis blasts out e-mails hawking ostentatious rip-offs as well as serpent oil, such as a dementia-reversing miracle therapy, a diabetes destroyer material as well as a life-saving cancer cells treatment that a Nazi drug store allegedly established at Hitlers command. Peppered in between these messages funded by third-party hucksters are main advertisements from Donald Trumps governmental reelection campaign.

For months, participants of the head of states internal circle consisting of Donald Trump Jr., Senate Majority Leader Mitch McConnell (R-Ky), previous House Speaker Newt Gingrich as well as also Trump himself have actually been releasing require contributions with the newsletter, which usually heads out 5 or even more times each day. Many receivers were most likely unintentionally subscribed; I Love My Freedom, the team that runs the eponymous newsletter, has actually obtained an expanding checklist of Americans call info with a concealed e-mail collecting system including an internet of pro-Trump Facebook web pages.

Right- wing political leaders, companies as well as media electrical outlets have a background of dealing with unethical entities behind the scenes to earn money as well as press their programs. The Trump campaigns service with I Love My Freedom is no exemption.

I Love My Freedom (e-mail information multiplied by HuffPost).

By layout, its e-mails seem theyre sent out straight from Trump as well as his allies, though theyre in fact dispersed by means of [emailprotected] At all-time low, they birth please notes noting they were spent for by either the National Republican Senatorial Committee, its House equivalent, the McConnell Senate Committee, or the Trump Make America Great Again Committee (which is collectively run by the Republican National Committee as well as Trumps reelection campaign).

Renting out accessibility to collected e-mail listings is a typical as well as very profitable method worked out by traditional as well as liberal teams alike, commonly for political fundraising objectives. But points obtain morally dirty when e-mail representatives do not veterinarian their enrollers which can lead to e-mail receivers being flooded with ripoffs as well as scams, like the counterfeit cancer cells treatment. In this instance, nonetheless, the genuine inquiry is whether Trumps group troubled to veterinarian I Love My Freedom.

The campaign did not react to HuffPosts ask for remark.

I Love My Freedom, which makes up the newsletter as well as a conservative blog site called Trending Politics, belongs to Making Web LLC, a rare advertising company thats signed up in Minnesota to a 51- year-old male called Allan G. Ferretti.

Through the newsletter alone, I Love My Freedom has actually enhanced a list of aggressive rip-offs consisting of some that misleadingly link Trump, in spite of its negotiations with his campaign. Hours prior to dispersing a fundraising e-mail from the McConnell Senate Committee this month, I Love My Freedom discharged off a funded message advertising a breakthrough stem cell therapy which it baselessly suggested Trump is getting.

This has got Liberals jumping out of their seats, the e-mail checks out. President Trump is in perfect health how is it that hes so seemingly immune to old age? Well in recent years, billionaires like President Trump have increasingly turned to the power of Stem Cells.

Titled Trump Health Bombshell, the e-mail web links to a rambling item pitch that promotes $67 containers of stem cell tablets as the Holy Grail of aging backwards. These tablets make cells inside your body become physically younger, it asserts, without supplying a shred of clinical proof. I Love My Freedom has likewise spammed its customers with enrollers get-rich-quick plans consisting of a secret IRS loophole, as well as has actually routed them to video clips recommending elders ought to exchange their recommended medicines for tricksters supplements also advising that they can pass away if they do not.

Recent newsletter versions have actually circulated actual phony information, as well, installing advertisements camouflaged as write-ups that connect to internet sites stealthily copying genuine media electrical outlets.

I Love My Freedom e-newsletters have actually included misleading advertisements resulting in phony information websites copying genuine electrical outlets..

One such advertisement includes the message Royal Family Mourns As Tragedy Is Confirmed, along with a picture of Meghan Markle, the Duchess ofSussex Clicking on it causes a web site imitating U.S.A. Today that goes crazy regarding a skin care line, which it incorrectly asserts Markle released. Another, birthing the heading [BREAKING NEWS] Prayers Go Out to Oprah Winfrey, web links to a fraudulent information website marketing a Brain Booster supplement, which it brazenly states is in charge of Winfreys occupation success.

In enhancement to Trump, his oldest kid, McConnell as well as Gingrich, I Love My Freedom has actually likewise sent fundraising e-mails in behalf of previous White House press assistant Sarah Huckabee Sanders, House Minority Leader Kevin McCarthy (R-Calif), House Republican Whip Steve Scalise (R-La), previous United Nations Ambassador Nikki Haley,Rep Elise Stefanik (R-N.Y.),Rep David Joyce (R-Ohio), previous White House Deputy Chief of Staff Karl Rove as well as National Republican Congressional Committee Chairman TomEmmer

All were spent for by the NRCC, NRSC, McConnell Senate Committee or the Trump Make America Great AgainCommittee Only the NRCC reacted to an ask for remark.

We rented this list to prospect new donors. We do our best to vet each vendor, but similar to renting a car, it is impossible to know or control what every other renter does with a list they too are renting, spokesperson Chris Pack informed HuffPost.

We will not be using this vendor going forward.

I Love My Freedom constructed its cash-cow e-mail realm by spending virtually $2 million right into Facebook advertisements, which attract individuals in with clickbait surveys or pledges of free MAGA equipment, as well as result in web pages advising them to send their e-mail addresses. This immediately indications them as much as obtain the newsletter, in addition to its numerous funded messages.

The team likewise earns money by marketing Trump- themed product such as Make Liberals Cry Again hats, as well as organizing third-party advertisements on Trending Politics which was seen a million times last month alone, according to electronic analytics device ComparableWeb

I Love My Freedom did not accept HuffPosts ask for a meeting.

I Love My Freedom makes use of clickbait Facebook advertisements to gather individualss e-mails, after that subscribes them to its newsletter.

Ferretti released ilovemyfreedom.org in addition to the Facebook web page Trump for President Fan Club (currently President Donald Trump Fan Club, which has 1.6 million fans) in the summertime of 2015, as reporter April Glaser reported last loss in a write-up regarding I Love My Freedoms viral development on Facebook.

Its among greater than a lots preferred web pages the team runs to run its countless Facebook advertisements, consisting of Donald Trump Is My President, Donald Trump 2020 Voters, President Trump Has My Vote, Donald Trumps Americans, Team Trump Fan Club, The President Trump Fan Club, We Need Trump 2020 as well as President Trumps Patriot Army.

These web pages create a stream of hyper-partisan memes as well as Trending Politics post to their target market of millions. Boosted by Facebooks formula, the advertisements which largely target elders are in some cases seen thousands of countless times each.

This looks like an operation thats got a very highly engaged audience that would be a prime target for a lot of conservative politicians to try to raise grassroots money from, stated Michael Beckel, research study supervisor at the political reform team Issue One.

When you run a pro-Trump Facebook team with greater than a million participants, that can make your [email] checklist an appealing possession.

Trumps campaign has actually currently gathered a citizen e-mail checklist thats so big it leases it out to outdoors celebrations. So why would certainly his group wish to fundraise with I Love My Freedoms checklist particularly provided the teams historical connections to grifters as well as scam artist?

Its type of striking that the Trump campaign is making a financial investment in [I Love My Freedoms] checklist, kept in mindBeckel But a t completion of the day, he stated, much more e-mails still means more potential voters or donors for them.

Calling all HuffPost superfans!

Sign up for subscription to come to be a starting participant as well as aid form HuffPosts following phase

Original post:
Donald Trump Is Using An Insanely Sketchy Newsletter To Find Campaign Donors - The Union Journal

Tom Coburn, an ultraconservative Oklahoma Republican and family physician who in 16 years in Congress crusaded for limited government, using a rule-book technicality to block so many bills that frustrated legislators called him Dr. No, died on Saturday in Tulsa. He was 72.

The cause was cancer, said John Hart, his former communications director. Mr. Coburn had said in 2013 that he was being treated for a recurrence of prostate cancer, and in 2014 he announced that he would retire.

Mr. Coburn was an obstetrician who treated some 15,000 patients and delivered 4,000 babies in a maternal and family practice in Muskogee, Okla., before embarking on his political career three terms in the House of Representatives (1995-2001) and, after a four-year hiatus, two terms in the Senate (2005-15). He retired two years before the end of his second term because of deteriorating health.

A visceral foe of Washington long before such disaffections coalesced into the Tea Party, Mr. Coburn swept into Congress with the class of 1994, when Republicans gained control of the House for the first time in 40 years and installed Newt Gingrich as speaker and his Contract With America agenda to shrink government, cut taxes and promote welfare reforms and business activity.

Mr. Coburn soon set about displeasing everyone, including the constituencies most politicians covet: his own partys activists, donors, leaders and congressional colleagues. He battled with Mr. Gingrich often, charging that he was drifting to the political center and away from his contractual pledges to the nation. He openly vented his disdain for career politicians.

His contempt for them is genuine, bipartisan and in many cases mutual, The New York Times reported years later. He once prescribed a spinal transplant for 70 percent of the Senate, and another time said his colleagues had reproductive organs the size of BBs.

As if separating himself from the pack, Mr. Coburn continued to deliver babies as a member of the House. (He gave up his obstetric moonlighting only after a dispute with ethics officials when he entered the Senate.) But he won grudging respect as a political maverick and was admired by some colleagues as one of the toughest fiscal and social conservatives of his era.

For the sake of smaller government, he voted against nearly all spending bills, particularly pork-barrel allocations for the pet projects of legislators. He opposed gay rights, same-sex marriage, embryonic stem-cell research and abortions except those to save a womans life. He denied that global warming was real. He favored term limits for elected officials and pledged to abide by them himself.

In the House, he supported gun rights and favored the death penalty, even for doctors who performed abortions. He also wrote laws aimed at protecting infants from AIDS and expanding medical care for the elderly. He helped reform welfare and other federal entitlement programs, and led workshops for young staff members on sexually transmitted H.I.V. infections.

He caused a stir in 1997 when he protested NBCs decision to televise, in prime time and without editing, Schindlers List, Steven Spielbergs Oscar-winning Holocaust film. He called it televisions all-time low, with full-frontal nudity, violence and profanity, adding, I cringe when I realize that there were children all across this nation watching this program.

He was heavily criticized, including by the American Jewish Congress, which said: This isnt Melrose Place, Mr. Coburn. This is the Holocaust. He apologized to all those I have offended, but insisted that the film should have been aired later in the evening.

Keeping his campaign pledge to serve no more than three consecutive terms in the House, Mr. Coburn did not run for re-election in 2000. He resumed his medical practice, and in 2002 was appointed by President George W. Bush as a co-chairman of his advisory council on H.I.V. and AIDS, giving him a prominent platform as he prepared to run for the Senate.

Mr. Coburn also wrote a book about his experiences in Congress, Breach of Trust: How Washington Turns Outsiders Into Insiders (2003, with Mr. Hart). In it, he called careerism the central tenet of Congress. Both parties today, he wrote, are ultimately controlled not by ideas, but by the desire to be in control, a posture that creates little motivation for bold change.

In 2004, Mr. Coburn won the Senate seat being vacated by a four-term Oklahoma Republican, Don Nickles. He handily defeated former Representative Brad Carson, a Democrat.

Mr. Coburn continued his conservative fiscal and social voting record, but with far wider public and media attention. He became notorious for using a procedural senatorial privilege, called a hold, with which a single senator could block bills from being voted on by the full Senate.

At first his obstructionist tactics were relatively innocuous. He blocked two 2007 bills honoring the 100th birthday of Rachel Carson and her landmark 1962 book, Silent Spring, which documented the environmental effects of pesticides. Mr. Coburn called the book junk science and the catalyst in the deadly worldwide stigmatization against insecticides, especially DDT.

Later bills blocked by Mr. Coburn included provisions for health care, penalties for child pornography and protections for natural resources. Senate business was dragging to a crawl under the tactical loophole he was exploiting.

In 2008, to expose and embarrass Mr. Coburn, the Senate majority leader, Harry Reid, introduced 35 of the most irresistible-sounding bills together as omnibus legislation. It was a benign collection that almost any senator would be ashamed to vote against: a Mothers Act to relieve postpartum depression, a Protect Our Children Act to thwart internet predators, and a shameless measure to commemorate The Star-Spangled Banner.

Tom Coburn put a hold on the package, which was mocked as the Tomnibus bill. He did not back down. Neither did Senate Democrats.

The struggle lasted two years, but came to a head when he put a hold on a bill to fund the disarming of the Lords Resistance Army, a Ugandan terrorist group that had massacred countless civilians and dragooned children into its ranks. After an 11-day round-the-clock protest outside Mr. Coburns office by people outraged that funds to suppress terrorists were being held up, he relented and the bill passed.

Re-elected in 2010, he pledged not to seek a third term. He left the Senate in early 2015 after retiring for health reasons, but continued to write and speak against government waste and profligate spending.

Thomas Allen Coburn was born in Casper, Wyo., on March 14, 1948, to Orin Wesley and Anita (Allen) Coburn. In Muskogee, where the family settled, his father was an optician who founded Coburn Optical Industries, which made ophthalmic equipment and eyeglass lenses. The company was sold to Revlon for $57 million in 1975, although the elder Mr. Coburn continued as president of the subsidiary. Tom Coburn graduated from Central High School in Muskogee in 1966.

In 1968 he married Carolyn Denton, the 1967 Miss Oklahoma. They had three daughters: Callie, Katie and Sarah, the operatic soprano. He is survived by his wife, his daughters and nine grandchildren.

At Oklahoma State University, Mr. Coburn was an honors student and president of the student business council. He graduated in 1970 with a bachelors degree in accounting. From 1970 to 1978, he was the manufacturing manager of the ophthalmic division of Coburn Optical Industries in Colonial Heights, Va.

After the family business was sold, he attended medical school at the University of Oklahoma and received his medical degree with honors in 1983. He interned at St. Anthony Hospital in Oklahoma City, had a residency at the University of Arkansas Health Education Center in Fort Smith and returned to Muskogee to open his family and obstetrics practice.

He was a deacon of the Southern Baptist Church and participated in medical missions to Haiti in 1985 and Iraq in 1992.

His decision to run for Congress in 1994 was a long shot. He narrowly won, becoming the first Republican to represent Oklahomas Second Congressional District in 73 years.

Mr. Coburn had homes in Muskogee and Tulsa. Besides Breach of Trust, he wrote two books: The Debt Bomb: A Bold Plan to Stop Washington From Bankrupting America (2012, with Mr. Hart) and Smashing the DC Monopoly: Using Article V to Restore Freedom and Stop Runaway Government (2017), about a plan for the states to amend the United States Constitution.

While he never drifted from his conservative convictions, Mr. Coburn forged a friendship in Washington that was as unlikely as it was enduring. Arriving in the Senate together in 2005, he and Barack Obama quickly bonded.

Shortly before he retired, Mr. Coburn said of Mr. Obama: I think hes a neat man. You dont have to be the same to be friends. Matter of fact, the interesting friendships are the ones that are divergent.

Jonathan Martin contributed reporting.

Continued here:
Tom Coburn, the Dr. No of Congress, Is Dead at 72 - The New York Times

IRON RANGE Veterinary offices across the state are forced to make temporary changes to their operations to help keep their staff and their clients safe during the coronavirus crisis.

Dr. David Kalinowski, a veterinarian for 31 years and owner of Mesabi Animal Hospital in Hibbing, told the Tribune Press on Monday that following a recommendation from the Minnesota Board of Veterinary Medicine his office and other veterinary clinics and hospitals are admitting animals from outside their offices to limit human interaction between clients and their staff.

The staff at Mesabi Animal Hospital in addition to Kalinowski, includes Dr. Molly Feiro, along with four veterinary technicians, two technician assistants and two receptionists.

Clients are being asked to call the veterinary office from their vehicles when they arrive for their pets appointment as the lobby and exam area are temporarily closed to pet owners. The veterinary staff for now is also doing intakes and exchanging information about the animals condition over the phone.

Clients are asked to place their animal in a pet carrier to make it easier for the veterinary staff to get the animal from the parking lot to inside the office. Once they are done treating the animal, it then will be returned to the owner outside while practicing social distancing.

I have to say people have been very understanding and its gone well, Kalinowski said.

Elective procedures for veterinary offices are also suspended at this time, per orders from the governors office. In the meantime, the Minnesota Board of Veterinary medicine has made an extension on vaccinations, so a one-year vaccination is now good for 18 months.

Kalinowski said animals that are ill and emergency cases are still being seen.

Emergency surgeries such as tumor removals or to treat lacerations are also allowed to continue.

Flea and tick preventatives are recommended to start in mid-April, so theres still a little time before those products are needed as well.

Dr. Harvey Aluni, of Northland Animal Hospital in Virginia, also shared his thoughts about the importance of keeping his staff and clients safe to help prevent the spread of the coronavirus (COVID-19).

There are 14 of us working inside Northland Animal Hospital and if anyone gets sick and tests for Covid 19, we may have to close completely for a while, Aluni wrote in an email to the Tribune Press. We are trying to keep our clients safe.

A veterinarian with nearly 50 years of experience, Aluni founded Northland Animal Hospital in 1973. When he opened his practice, his staff consisted of his mother, who was the receptionist and one assistant. The present staff consists of four veterinarians: Dr. Brian Aluni, who is Harvey Alunis son, along with Dr. Abby Pontinen and Dr. Valerie Wright.

Northland Animal Hospital is also temporarily limited to providing care for sick animals, along with treating emergencies and conducting emergency surgeries and euthanasias.

The inside office and exam room are off limits to clients, to avoid close contact between humans.

Clients are asked to call from the parking lot when theyve arrived for their pets appointment. Questions and concerns about the pets condition will be addressed over the phone.

A member of the veterinary staff will then bring the pet inside the office to be cared for and return it to the owner outside once its ready to go home.

Harvey Aluni said clients may also stand outside the door of the building, provided they stay at least six feet away, keeping with social distancing.

Northland Animal Hospital will continue to comply with the most recent directives from the governor and the board, while noting the situation is changing day by day.

Read more:
Veterinary offices take measures to protect staff and public - Hibbing Daily Tribune

Event

123rd annual meeting, Oct. 24-30, Providence, Rhode Island

The meeting, held jointly with the American Association of Veterinary Laboratory Diagnosticians (see story), drew nearly 1,300 attendees. Dr. Juan Lubroth, chief veterinary officer for the United Nations Food and Agriculture Organization, presented the keynote address Understanding and Overcoming the Challenges for the Control of African Swine Fever: A Global Threat in Your Backyard.

USAHA Medal of DistinctionDr. Belinda Thompson (Cornell 81), Ithaca, New York. Dr. Thompson has served as an assistant clinical professor in the Department of Population Medicine and Diagnostic Sciences at Cornell University College of Veterinary Medicine since 2002. Prior to that, Dr. Thompson was in large animal practice in Pine City, New York. She was recognized for her broad impact on the association, local producers, and veterinarians and at a national level.

USAHA Federal Partnership AwardDr. Barbara Porter-Spalding (Michigan State 91), Raleigh, North Carolina. Dr. Porter-Spalding is a senior staff officer with the U.S. Department of Agriculture Animal and Plant Health Inspection Services Veterinary Services. She was honored for her collaborative efforts in training and exercise programs as lead on the VS Training and Exercise Plan and for her efforts toward improving emergency preparedness.

APHIS Administrators AwardDr. Beate Crossley, Davis, California. A 1994 veterinary graduate of Free University of Berlin in Germany, Dr. Crossley is an associate professor and virologist at the University of California-Davis California Animal Health and Food Safety Laboratory.

National Assembly AwardDr. Susan Keller (Kansas State 85), Mandan, North Dakota. Dr. Keller is the North Dakota state veterinarian. She was recognized for her leadership and tireless commitment to animal health.

Thirty-one resolutions were approved and can be viewed at usaha.org/usaha-resolutions.

Dr. Martin Zaluski, Helena, Montana, president; Dr. Charles Hatcher, Nashville, Tennessee, president-elect; Dr. Dustin Oedekoven, Pierre, South Dakota, first vice president; Steve Rommereim, Alcester, South Dakota, second vice president; Dr. Manoel Tamassia, Trenton, New Jersey, third vice president; Dr. Annette Jones, Sacramento, California, treasurer; and Dr. Kristin Haas, Montpelier, Vermont, immediate past president

Original post:
United States Animal Health Association | American Veterinary Medical Association - American Veterinary Medical Association

Veterinary medicine is an applied science. We take available research information and use it to make the best possible decisions in real world settings. This can be very challenging. But the entire process by which we try to expand the knowledge base in our field is fascinating in its own respect.

We rely heavily on statistics. On a basic level, I think this is very intuitive. What is a veterinarian, or a physician, or an educator, or an engineer, or a builder, or a farmer, but a keen observer in their field? Each respective profession can observe that treating a condition a certain way is more likely to achieve the desired result. Recording observations over a long period of time allows us to make accurate predictions, for example, that 90% of cows with gangrenous mastitis will die, and create benchmarks, for example, that incidence of displaced abomasum in fresh cows should be less than 5%.

Sometimes, though, there are more complicated questions for instance, we may observe the incidence of fresh cow DA, but now we want to know why cows get DAs so that we can do something about it. These more complicated questions also require more sophisticated methods of analysis.

A few years ago, we did a study in our practice. I would like to use it as an example to demonstrate the nature of science.

I was talking to my partner, Dr. Bill Croushore, one day and asking him what criteria he uses to determine whether or not a cow with a displaced abomasum was a good candidate for surgery. There are many identified risk factors for poor outcomes following surgery mastitis and lameness at time of surgery, for example, are poor prognostic indicators. That doesnt mean the surgery wont go well. It may mean that those cows are likely to be culled because of concurrent issues.

Science does not answer all the questions at once. As a matter of fact, in order to create a valid study, the investigators need to be very clear and specific about the question they are setting out to answer.

We wondered whether or not there might be a reliable way to quickly determine how a cow with a displacement would fare following surgery. Dr. Bill designed and authored a study about the use of a simple cow-side blood test as a prognostic indicator for outcome of LDA surgery.

There are some weak similarities between diabetic ketoacidosis in humans and ketosis because of negative energy balance experienced by lactating dairy cows. A human meter for a type of ketone known as beta-hydroxybutyrate is available commercially, and research has also validated the use of this meter for ketosis in cattle. This was the simple blood test we chose to use. It requires a few drops of blood, costs about $6, and gives a result in about 10 seconds. We felt that spending $6 for prognostic indication before investing several hundred dollars was worthwhile.

The first step in creating your study is to clearly define what you are trying to answer. In our case, we wanted to know whether or not we could use a BHB level to evaluate our surgical candidates. Simple question, right?

Now it starts getting more complicated. Next, we formulate what we call the null hypothesis. This is usually the opposite of what we think or are trying to prove, and it will probably never be stated in the final research paper. Our null hypothesis would have been something like, There is no relationship between the measured BHB value and the outcome, measured by 30-day survivability, following LDA surgery.

The goal of our study, then, is to allow us to reject this null hypothesis and prove that there is, in fact, a relationship between BHB and surgical outcome. Remember how I said we rely on statistics?

Statistical analysis of the data can be done in many ways, but in our case, it will give a value known as p. This is a probability. Science does not deal in absolutes. The p value is the probability that we can correctly reject the null hypothesis. By convention, we are willing to accept a 5% chance of error in rejecting the null hypothesis. This corresponds to a p value of 0.05 or less (5% expressed as a decimal).

In other words, if our study is designed correctly and if we use the correct statistical analysis, and p<0.05, we can reject the null hypothesis and state that BHB is, in fact, related to surgical outcome. This is referred to as statistical significance. If the p value is <0.01 or even 0.001, the relationship is even stronger.

A familiar example of this type of significance can be found on the milk you buy in the store. A few years ago, some co-ops and dairies decided they would require their producers to produce milk without the use of rBST. They advertised the milk as such.

The advertising was seen as harmful to the sale of milk that was produced using rBST and so following research on the topic, the non-rBST milk was required by law to put a statement on their labeling saying that research had shown no significant difference in milk from rBST and non-rBST treated cows. That does not mean that somebody eye-balled them and they seemed pretty similar. It means specifically that in all the parameters they tested, they were unable to reject the null hypothesis that the milks were no different.

Moving through our study, we had to establish a surgical protocol. We collected blood samples, recorded physical exam data on our patients, and decided what follow-up treatments they would receive. To be included in the study, the cows had to meet the criteria, and they had to be treated according to the protocol to eliminate confounding of data because of inconsistencies.

After 30 days, we called to follow up and see how the cows were doing and if they were still in the herd.

One of the challenges we face is sample size, which is denoted by the letter n. Statistical significance is affected by how many test subjects you use. For example, if you ran a study and looked at only two cows, your results would not mean much. By looking at larger groups of animals, you can minimize the variation because of an individual animal and get a truer reflection of the population. Our goal was to get about 150 animals (n=150). It took a while.

In the end, we went through all the work and found that there is, indeed, a useful relationship between BHB and surgical outcome, but the p value does not indicate what that relationship is. One of my favorite things about our study and its design was something we never expected.

The basic statistics allowed us to confirm the relationship we were looking for. We had a lot of help from several professional biostatisticians who co-authored our study. Remember all the data I said we collected? They were able to use that data to characterize the relationship.

In short, we were banking on a higher BHB value being an indication of fat storage in the liver and a poor prognostic indicator, and assuming that lower BHB values were better surgical candidates. The data showed otherwise.

Lower BHB values indicated a poorer prognosis and we speculate that this is because of more long-standing conditions, such as DAs that had not been found as quickly, and cows that were no longer able to mount the appropriate ketone response.

The statisticians were able to suggest a useful cut point for BHB (i.e., if the BHB is above a certain level, the data suggest this cow is a reasonable surgical candidate, and vice versa).

Such is the nature of science. Because the study was properly formulated and analyzed, we were able to confirm with statistical certainty what we suspected, but also tipped off to where our expectation was not correct.

In preparing the final version that was published in Journal of the American Veterinary Medical Association, Dr. Bill did a literature search and framed our study in light of the available scientific information to date.

Since its publication, our study has been cited a number of times in other research papers. By asking the right questions and performing thorough and meticulous investigation, our profession is able to build on itself, moving forward in small increments.

On the contrary, overreaching where information is scarce and leaping forward based on anecdotal information and consensus can be very problematic but thats a topic for next month.

See more here:
Veterinary medicine and the nature of science | Columns - Daily American Online

With his Miami practice, Southeast Veterinary Neurology, thriving, a daily commitment to health that keeps him centered, and a tight family bond, Dr. Michael Wong is feeling psyched for the future.

Dr. Michael Wong is one of fewer than 300 board-certified veterinary neurologists practicing in North America. He graduated magna cum laude from the University of Florida (UF) College of Veterinary Medicine and while there, founded the Universitys Veterinary Business Management Association.

He went on to complete a medical and surgical internship at Red Bank Veterinary Hospital in New Jersey and he received his neurology and neurosurgery training at North Florida Neurology.

After completing his residency, Dr. Wong successfully passed his examination and became board-certified in veterinary neurology in the same year. He founded Southeast Veterinary Neurology (SEVN) in 2010.

We caught up with cool dad of three to learn more:

If I wasnt a veterinarian what would I be:

Ive always wanted to be a veterinarian, so I havent put much thought into that question.Prior to veterinary school I was a life guard at the beach and really enjoyed that.Maybe something with the ocean?Marine biologist?Tour guide?Not sure.

Best career advice I ever received:

Its a marathon, not a sprint.My first year out of veterinary school, Dr. Rick Glass, the neurologist at my internship used to say this.The particular context he used it in was with reference to another veterinarian who didnt think about the effects her decision had on referring vets wanting to refer to her in the future.

Its really shaped the way I view things.I have a long view.I think in the macro.I try to see the big picture.I make decisions based on the effects they will have in the long term as opposed to just the short term gain.I give up lots of short-term wins (profit, awards, etc) knowing that Ive made the right decision for my team and the pets and people that care for them.

How it felt becoming board certified:

Most people hated taking boards.Its a 2-day, five part test that has around a 30% pass rate.But for me, it wasnt stressful it was exciting.I was just putting down on paper all the knowledge I had been acquiring as part of living my dream of becoming a neurologist.

In between sections of the exam, I would head back to my room at the hotel.I remember thinking the lyrics from a song:Ive waited for this moment.Dreamed it every day.This is my one true purpose.It sounds cheesy, and Im sure many people had a very different experience around taking boards and are probably rolling their eyes at me right now.Its just my experience and a happy memory.

Easiest career decision I made

I wont call it the easiest, but certainly the best career decision I made was to open Southeast Veterinary Neurology.Practice ownership, entrepreneurship and leadership have opened up avenues in my life and career that I never would have had without them.

Related, Id say another best decision I made was to surround myself with people that share the vision of bringing hope to people and their pets.

Interesting way I made extra cash in vet school:

In vet school, I would make sushi at home and sell it to my classmates for lunch.Id take orders earlier in the week, buy the ingredients, make the rice, roll the sushi, then deliver at class.

Book that left a lasting impression on me:

Simon Sineks Leaders Eat Lastthis book is for those who want to feel they and their work matter and for those who want to inspire others to feel the same.

How I clear my head after a stressful day

Tennis.Family.Orangetheory.Orangetheoryis a science-backed, technology-tracked, coach-inspired group workout designed to produce results from the inside out.

What adventure most changed my life:

Meeting my wife, Myri-Ann. She was a St. Georges student, doing her clinical year of veterinary school at the University of Florida.Her first rotation was neurology, and we were on together.

I remember seeing her for the first time: she was the first person to the neurology rounds room, sitting nervously with her books on her lap, reviewing her notes.The neurology service was slow for those two weeks.Id come in early to help with neuro exams on her patients, since I didnt have any myself.I wasnt much of a help, as I still knew nothing about neurology at the time.She ended up getting an A and I got a B+.She likes to remind me of that.

We started off as friends.She was very hesitant to get romantically involved with someone from the mainland.Her plan was to go back to Puerto Rico and start a practice after finishing up school.

But, one day I walked her home after clinics were finished and we came across an earthworm struggling to cross the sidewalk in the Florida heat.She told me that her perspective on our romance changed when I picked the earthworm up and moved it to the grass.Im still indebted to that worm, because everything I have in my life right now (kids, family, house, business, etc) is because of this worm.

Whats my favorite way of spending a day off from work:

My perfect day would spending the day with my wife and then later picking up our kids and stopping by a park together on the way home.Play with Disney princesses, build Thomas the Train playset tracks, run around the back yard, exploring the dirt and hiding in the bushes.Jump in the pool.Cook dinner while the kids get a bath.Talk about the day at the dinner table: what we learned at school, who we sat with the lunch table, who we met, who we made smile, who we played with.Have the kids FaceTime with grandparents.Brush teeth.Read stories.Get ready for bed.

Connect with Dr. Michael on Linked in

See the original post:
Dr. Michael Wong on confidence, career, and the importance of family - Jill Lopez

Among the headlines from yesterdays meetings of the newly-empowered government and the national security council, one that caught the eye was the announcement of a cat diagnosed with coronavirus caught from its owner.

The cat was reported to have caught the virus from close contact with its owner, who had recently returned from Italy. When the cat became ill, its stool was examined and traces of the virus discovered.

The experts were quick to reassure pet owners that the case was exceptional, that animals were not considered a vector for the disease, and that there was no reason to be afraid either for their pets or for themselves.

But one animal virologist has raised questions about the whole story.

Hans Nauwynck is a professor at the faculty of veterinary medicine at the University of Ghent, and a specialist in virology. The news of the corona cat took him by surprise.

Before sending this news out into the world, I would have had some other tests carried out, he told Het Laatste Nieuws. When you hear about this right now, I wouldnt wish to be a cat tomorrow.

The discovery was made by the vet faculty at Liege university, who concluded the infection passed from human to cat and not the other way around.

Look, I have no criticism of my colleagues at Liege university, he stressed. The diagnosis has been made, Ive no doubt about the result, but were dealing here with a PCR test, a way of identifying genetic material of the virus.

The polymerase chain reaction (PCR) test allows scientists to multiply a very small sample of genetic material to produce a quantity large enough to study.

Im simply questioning the interpretation of the results. The test is positive for corona, fine, but how was the test carried out? How was the sample taken, and can that result be trusted? I would advise people to slow down. There may somehow have been genetic material from the owner in the sample, and so the sample is contaminated.

To be absolutely certain, he said, more tests should have been done to confirm the initial result, and certainly before making an announcement to the world.

I think its too bad they didnt look further, he said. There should also have been research carried out to see if the cat had produced antibodies. Im worried that people will be scared by this news and animals will be the ones to suffer, and thats not right. As scientists we ought to put out clear and full information, and I dont think that has happened.

In the latest update, the cat is doing well. Its owner is also recovering, albeit more slowly.

Alan HopeThe Brussels Times

Continued here:
The curious case of the cat with corona - The Brussels Times

Labs from both universities are working together to ensure the safety of all Iowans.

IOWA CITY, Iowa Iowans of all walks of life are stepping up to help stop the spread of COVID-19.

Iowa State University's vet diagnostic lab is using its equipment to help test people for the virus.

Normally, the lab detects infectious diseases in all types of animals.

But now it's helping out the state hygienic lab in Iowa City to increase testing of COVID-19.

"I can tell you, it's created, step wise, an enhancement of the capabilities," dean of the Iowa State University College of Veterinary Medicine, Dr. Dan Grooms said.

The Iowa State veterinary diagnostic lab is turning its effort to help COVID-19 response in Iowa.

"Our veterinary diagnostic lab is a state-of-the-art diagnostic lab that's set up to do animal testing at large scales. In fact, we do over 1-million tests here on an annual year," Grooms said.

They partnered with the state hygienic lab at the University of Iowa, which houses COVID-19 testing, by sending a bulk of equipment and expertise needed to increase the amount of COVID-19 testing in Iowa.

"By Friday morning we had instruments, people, reagents on its way to Iowa City and worked with their team there that's working around the clock at the hygienic lab over the weekend to on-board our hyput molecular extraction techniques into their work flow, they validated it into their workflow and on-boarded it. as of the testing, they started doing it last Saturday," director of the ISU veterinary diagnostic lab, Rodger Main said.

"This is what Iowans do under dire circumstances. We're looking for every opportunity we can to answer the call to solve this problem in the state of Iowa," Grooms said.

Right now, Iowa has the capacity to test 970 samples of suspected coronavirus cases.

Read more from the original source:
ISU and UofI teaming up to bring more COVID-19 tests to Iowa - Local 5 - weareiowa.com

Driving into work, I (Perry Jameson) no longer get the cherished 30-40 minute conversation with my wife alone without four children involved. For the past week, every morning from 8-8:30, Dr. Henri Biannucci and I are on a 30-60 minute conference call with our management team discussing the ever-changing landscape of COVID-19.

Now, we not only have to worry about treating our animal patients but also how we prevent our staff from contracting COVID-19. Since so many of our team are younger (20-30 years of age), they may be positive and not even know, thus exposing a pet parent unknowingly. How do we meet our social responsibility to do our part in blunting the spread of this disease while at the same time treating ill patients?

I spoke with the governors office yesterday and, while I did not get to speak with him, the women I did talk to felt we would be deemed an essential business should he decide to restrict which businesses remain open. That reassured me, as all I could think about if we were required to close was of a family with a pet having a life-threatening emergency and nowhere to go. This is not like a hurricane where we could send them to Columbia or Greenville, as those locations could be closed as well.

We also use the same medical supplies and personal protective equipment as those in human medicine. How do we conserve these resources in case our colleagues in hospitals for humans need them but still practice veterinary medicine the best we can?

Over the past week, our hospitals have adapted to try to accomplish all of those goals. Every day, we modify them to meet new changes and in ways we find that better serve our patients. Most of the other veterinarians in town have adopted similar policies.

We have dramatically decreased our case load. If a pet is healthy but has had some abnormal laboratory values for several months, they are safe to wait several weeks to be seen. Elective surgeries can wait. This strategy both lessens the number of people exposed to each other while also decreasing the medical supplies we use.

When a patient cannot wait, we have instituted new policies to prevent exposure. The first step is asking the following questions before any interactions occur. This is awkward for us as we are not used to asking humans about their own symptoms:

If they answer yes to any of these, we are more aggressive with our personal protective equipment. If no, we still wear a mask and gloves but no gown in order to preserve these.

Mom and Dad wait in the car while the patient is brought inside and examined. All communications are over the phone, and the parents are never allowed in the building. We email all discharge instructions so as not to exchange paperwork.

The most uncomfortable aspect is not allowing clients inside to use the restroom. Many of our patients come from several hours away to be seen. To accommodate this need but prevent exposure, we have placed portable toilets outside all three of our hospitals.

Every time we treat a patient with chemotherapy, we have to protect ourselves from being exposed to these agents. There are multiple steps taken, from a special negative vacuum hood, special devices to prevent any material from leaking when removing from the bottle, and dressing in personal protective equipment. Part of the equipment is the N95 mask, which will not only prevent you from inhaling chemotherapy agents but viruses as well.

One of our oncologists, Dr. Kathryn Taylor, was concerned whether we should be using the N95 masks while they are running out of them in human medicine. After calculating the number we had and by being more efficient with their use, she found we had enough to last several months. She has been in contact with a nurse to see if her hospital needs them.

As veterinarians, we are trying to do our jobs of treating your sick pets but to also do our part in reducing the spread of COVID-19 and save critical medical supplies for potential human use.

You can help us by being patient with the social distancing strategies we have put into place and seeking care only when necessary.

Read more from the original source:
Pet Docs: Meeting our patient and social responsibilities in the time of COVID-19 - Charleston Post Courier

INDIANOLA, Iowa -- If a pandemic hits the Corn Belt during the growing season, thats one thing. Butits planting season, and farmers have one eye on getting the crop in the fieldand one eye on keeping the new coronavirus away from their families.

Jim Lowe, college of veterinary medicine at University of Illinois, told visitors via a farmdoc daily webinar, Tuesday,thatCOVID-19is one that needs everyones attention.

In many ways, the virus is serving as adjvu moment for the animal medical field.

Oftentimes with animal diseases, its hard to tell which animals are infected vs. which animalsare carrying the disease thats spreading.

Animals can be infected but not diseased. And that is the same situation occurring in humans withCOVID-19.

As a result, the big challenge facing this pandemic is understanding case definition.

In other words, when the number of COVID-19 cases are quoted, that refers to the number of individuals who have tested positive (diseased).

Butwe know that is a gross underestimate of the people who are only infected with the virus in the country, Lowe says. So, weve got some real challenges with what the denominator is. The point being that all age groups can get infected and even now we are seeing that younger people are getting severely ill and passing away.

While describing the virus, its impact on U.S. hospitals, its origin, its patterns on the population, etc., Lowe suggested that folks visit covidactnow.org for more detailed information.

Normally, when a virus moves from animals to humans (known as zoonotic), it doesnt adapt very well, doesnt replicate, and pass from human to human. Therefore, the virus doesnt spread much and is of very little threat.

Obviously, that is not the case with the new coronavirus, Lowe says.

Lowe says its helpful to understand that being diseased means that a human was exposed to a pathogen and that pathogen caused the person to have a response, getting sick.

People are exposed to pathogens and viruses everyday, but the immune systems handle that, for the most part.

Being infected, but not diseased, is especially important to understand with COVID-19.

Someone who is infected and is shedding can be infecting others, Lowe says. That is one of the big differences with this coronavirus and the first SARS outbreak (known as COV-1), also originating from China.

That virus didnt transmit very well between its hosts.

Also, it was easy to tell the people that ifinfectedwere also diseased, Lowe says.

Its very apparent with this years virus that we have a lot of infected people who are not diseased. Those infected people are infectious, meaning they can cause someone else to be infected, without knowing it, Lowe explains.

For these reasons, its hard to know who to be around and not get infected.

If I cant figure out where all the infected people are, or, in my animal science profession, where all the infected pigs or cattle are located, my only choice is to stop movement, Lowe says.

When trying to control infectious diseases, veterinarians consider that every animal fits in one of three categories.

Either the animal is infected, resistant to infection, orsusceptible to infection.

To control the spread of the novel virus, i.e., COVID-19 coronavirus, the key is to keep the susceptibles away from the infected. If I dont know who the infected are, its really hard to keep the susceptibles from being contacted, Lowe says.

So, this is why farmers are urged to be carefulas they go about their business of planting, chores, etc.

The virus can live on hard surfaces such as tools, pickup truck handles, steering wheels, etc. for three days. Those of us in agriculture, there is a tendency to be the tough guy. Its not a time for farmers to be that tough guy. If you get sick, after getting on the tractor to plant, get yourself isolated and dont infect your family, Lowe says.

Lowe added, Its a good idea to wipe off pickup truck handles with a sanitizer. Farmers have to go do their job, but they should wash their hands, wash their hands, and wash their hands.

While people shouldnt take this pandemic lightly, Lowe doesnt believe living in fear is the answer, as the weeks and months go on.

While serving as a state fair veterinarian, Lowe sees it as too early to tell if the nations county and state fair celebrations will need to be canceled.

I think its going to be touchandgo. I would guess that we are going to be somewhat conservative much like the sporting events. The early state fairs could be off and I hate to even gather a guess at what could be happening by August. Its either going to be better or worse, Lowe says.

The good news is that there is zero evidence that this coronavirus infects anything other than human beings, he says.

Lowe encourages truck drivers to be cautious, as they have a lot of contact hauling livestock to packing plants and elsewhere.

Lowe joined the University of Illinois farmdoc experts, Tuesday, on a webinar focused onCOVID-19and U.S. agriculture. The webinar has been archived at farmdocdaily.illinois.edu. Look for the YouTube icon.

See original here:
With COVID-19, farmers urged to resist being the tough guy, veterinarian says - Successful Farming

While some of our bodys cells divide in a matter of hours, the process of making sperm, meiosis,alonetakes about 14days from start to finish. And fully six of those days are spent in the stage known as the pachytene, when pairs of chromosomes from an individuals mother and father align and connect.

This stage is really important, because the pair needs to be aligned for the exchange of genetic material between those two chromosomes, says P. Jeremy Wang, a biologist in Penns School of Veterinary Medicine. If anything goes wrong at this stage, it can cause a defect in meiosis and problems in the resulting sperm, leading to infertility, pregnancy loss, or birth defects.

In a new paper in Science Advances, Wang and colleagues have identified an enzyme that plays a crucial role in maintaining this chromosomal pairing during the pachytene stage of meiosis. Without this protein, named SKP1, meiosis cannot proceed to metaphase, the next major developmental stage involved in generating sperm cells.

The finding may help overcome hurdles that have stood in the way of treating certain forms of male infertility, in which a man makes no sperm but in whom sperms precursor cells, spermatogonia, can be found.

Reproductive technologies like in vitro fertilization have made a huge difference for infertile patients, but the male needs to have at least some sperm, says Wang. If the male has no sperm, then the only option is to use donor sperm. But if you can find these spermatogonia, the pre-meiotic germ cells, they could be induced to go through meiosis and make sperm. So SKP1 could be part of the solution to ensuring meiosis continues.

Wang is also hopeful that his finding could aid in basic research on sperm development that his and many other labs pursue.

Right now we use animals to do our research; we dont have a cell culture system to produce sperm, he says. Manipulating SKP1 and the pathway in which it acts could allow us to set up an in vitro system to produce sperm artificially, which would be a boon for our studies.

The publication represents nearly a decade of work, led by Wangs postdoctoral researcher Yongjuan Guan, with major contributions from former postdoc Mengcheng Luo.

The team began focusing on SKP1 after conducting a screening test to look for proteins found in the area where the paired chromosomes come together during the pachytene stage of meiosis. From earlier studies, the researchers knew that SKP1 also plays a role in cell division in cells throughout the body, not just sperm and eggs. Without it, cells die.

That fact forced the Penn Vet team to get creative to understand the proteins function. Unable to simply eliminate it, they created a model system in mice in which they could turn off the protein only in the germ cells and only in adulthood.

Taking this inducible, germ-cell-specific model, we found that taking away SKP1 caused the chromosomes to prematurely separate, says Wang.

While the normal alignment process in the pachytene stage takes six days in mice, in the cells that lost SKP1 the paired chromosomes separated far earlier.

Scientists had hypothesized the existence of a metaphase competence factor, or some protein required for a cell to enter metaphase. Wang believes that SKP1 is it.

While introducing a compound known as okadaic acid to sperm precursor cells can coax them into an early entrance to metaphase, cells lacking SKP1 did not progress to metaphase.

Experiments in developing eggs showed the researchers that SKP1 is also required for females to maintain viable eggs. Oocytes, the cells that develop through meiosis to form mature eggs, that lacked SKP1 developed misaligned chromosomes and many eventually were lost.

In future work, Wang and his colleagues want to dig deeper into the mechanism of action by which SKP1 works to ensure cells can progress to metaphase, with the idea of eventually manipulating it to find strategies for addressing infertility and innovative laboratory techniques.

Now that we know SKP1 is required, were looking for the proteins it interacts with upstream and downstream so we can study this pathway, says Wang.

Wang, Guan, and Luos coauthors on the paper were Penn Vets N. Adrian Leu, Jun Ma, and Gordon Ruthel; Penn School of Arts and Sciences Biology Departments Luks Chmtal and Michael Lampson; and Cornell Universitys Jordana C. Bloom and John C. Schmienti. Luo is now a faculty member at Chinas Wuhan University.

Support for the work came from the National Institute of General Medical Sciences (grants GM118052 and GM122475), National Key Research and Development Program of China (Grant 2018YFC1003400), National Natural Science Foundation of China (Grant 31771588), Thousand Youth Talents Plant, and National Institute of Child Health and Human Development (grants HD082568 and HD057854).

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A critical enzyme for sperm formation could be a target for treating male infertility - Penn: Office of University Communications