StemCell Therapy

NIH grant funds an interdisciplinary effort among researchers from University of Southern California; University of Washington and Fred Hutchinson Cancer Research Center; Harvard University and Massachusetts General Hospital; the Ragon Institute; and Magenta Therapeutics

Magenta will utilize its tool CD45 and CD117 antibody-drug conjugate (ADC) conditioning agents, as well as its stem cell biology platform to identify the optimal strategy for curative immune system transplant in patients with HIV

Magenta Therapeutics (Nasdaq: MGTA), a clinical-stage biotechnology company developing novel medicines to bring the curative power of immune reset to more patients, today announced it is part of a multi-project, broad-based research effort awarded a five-year, $14.6 million U19 grant from the National Institutes of Health (NIH) to explore gene- and cell-based approaches to advance research into curing HIV.

This cross-institutional research program brings together leaders in the fields of gene editing, HIV and stem cell transplant. The team, which includes researchers from the University of Southern California, the University of Washington, the Fred Hutchinson Cancer Research Center, Harvard University, Massachusetts General Hospital; the Ragon Institute and Magenta Therapeutics, will explore novel hematopoietic stem and progenitor cell (HSPC) engineering and transplantation approaches aimed at achieving complete remission of HIV-1 infection.

"We are excited to collaborate with our colleagues in this important multi-institution research team to help advance gene editing approaches with our novel targeted antibody drug conjugate (ADC) conditioning platform to one day be able to cure patients living with HIV," said John Davis Jr., M.D., M.P.H., M.S., Head of Research & Development and Chief Medical Officer, Magenta. "These studies leverage our proprietary stem cell biology pipeline and ADC platform to provide important insights into which conditioning strategy is best suited to aim for HIV."

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Magenta will utilize its conditioning technology to optimize cell dose in animal models and determine whether targeted conditioning and gene-modified HSPC transplant enables disease control.

About Magenta Therapeutics

Magenta Therapeutics is a clinical-stage biotechnology company developing medicines to bring the curative power of immune system reset through stem cell transplant to more patients with autoimmune diseases, genetic diseases and blood cancers. Magenta is combining leadership in stem cell biology and biotherapeutics development with clinical and regulatory expertise, a unique business model and broad networks in the stem cell transplant world to revolutionize immune reset for more patients.

Magenta is based in Cambridge, Mass. For more information, please visit http://www.magentatx.com.

Follow Magenta on Twitter: @magentatx.

Forward-Looking Statement

This press release may contain forward-looking statements and information within the meaning of The Private Securities Litigation Reform Act of 1995 and other federal securities laws. The use of words such as "may," "will," "could", "should," "expects," "intends," "plans," "anticipates," "believes," "estimates," "predicts," "projects," "seeks," "endeavor," "potential," "continue" or the negative of such words or other similar expressions can be used to identify forward-looking statements. The express or implied forward-looking statements included in this press release are only predictions and are subject to a number of risks, uncertainties and assumptions, including, without limitation risks set forth under the caption "Risk Factors" in Magentas Annual Report on Form 10-K filed on March 3, 2020, as updated by Magentas most recent Quarterly Report on Form 10-Q and its other filings with the Securities and Exchange Commission. In light of these risks, uncertainties and assumptions, the forward-looking events and circumstances discussed in this press release may not occur and actual results could differ materially and adversely from those anticipated or implied in the forward-looking statements. You should not rely upon forward-looking statements as predictions of future events. Although Magenta believes that the expectations reflected in the forward-looking statements are reasonable, it cannot guarantee that the future results, levels of activity, performance or events and circumstances reflected in the forward-looking statements will be achieved or occur. Moreover, except as required by law, neither Magenta nor any other person assumes responsibility for the accuracy and completeness of the forward-looking statements included in this press release. Any forward-looking statement included in this press release speaks only as of the date on which it was made. We undertake no obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events or otherwise, except as required by law.

View source version on businesswire.com: https://www.businesswire.com/news/home/20200902005248/en/

Contacts

Magenta Therapeutics: Lyndsey Scull, Director, Corporate Communications202-213-7086lscull@magentatx.com

Dan Budwick1ABdan@1abmedia.com

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Magenta Therapeutics Named Co-Recipient of Grant from the National Institutes of Health to Explore Use of Novel Targeted Conditioning Agents with Gene...

In a society focused on visual communication, being blind can have severe disadvantages. In fact, research shows blind people are at higher risk of unemployment, social isolation, and lower quality of life than sighted people. Given the huge impact blindness has on society and those without vision, the drive to find a cure for blindness has become a profitable market.

Many new, cutting-edge developments that cure blindness build on promises they often cannot keep, leaving many blind people and their families feeling disappointed and disillusioned. But what does curing blindness actually mean and how can it be achieved in a way that it most benefits the blind person?

When we think of curing blindness, we often think about restoring the lost sense for example, through vision-enhancing technology, bionic eyes, or gene therapy. This is because we typically treat an impaired sense by focusing on the damaged sensory organ. But while our eyes deliver the sensory input, by transforming light into electrical impulses that our brains can use, most visual perception happens in the brain.

The perception of a visual object, a coffee cup, say, is created across different hierarchical levels in the visual cortex of our brain. Simple two-dimensional features, such as edges and colours, are combined into more complex shapes, which are in turn combined into the perception of whole objects, like our coffee cup. Across these different levels, our previous visual and non-visual experiences strongly influence how we perceive the final object.

Because of the complex nature of visual perception, sight is incredibly difficult to restore, and achieving a satisfactory level of visual function is not easy. Despite significant advances in visual restoration technology, even the best visual implants typically only allow visual acuity of 1/60, which is technically still classed as blindness by the World Health Organization. While this minimal form of light perception is already great progress, its not enough to allow a person to live independently.

While every blind person has their own ideas of what sight rehabilitation should do for them, what resonates with most is the aim to increase independence by allowing blind people to gain more access to visual information.

But does the brain need vision for that? Not necessarily. This is why we need to adopt a different perspective on sensory rehabilitation one that views vision as part of a greater multisensory experience. After all, perception is rarely based on one sense alone but on a combination of multisensory experiences in which our senses influence each other.

The brain has the remarkable ability to compensate for sensory loss by reorganizing how it processes information. In fact, the brain learns to perceive through the sensory experiences it makes during childhood. If all sensory experience is non-visual, perception will develop around these experiences. So if a person was born without sight, or lost their sight early on in childhood, their perception will develop around the non-visual senses.

This is why, on some tasks, blind people perform better than sighted people, while, on other tasks, they may perform worse. This dichotomy seems to underlie a simple principle: is the sense that is typically used for this task the best suited for accessing this information? For example, we are well able to locate a buzzing phone using either our vision or hearing. In this case, more experience finding objects through sound will lead to superior performance in blind people when only hearing is used. However, given that our vision is much better suited to perceiving peoples faces, blind people usually perform worse than sighted people when recognising others faces through touch.

We know that the brain learns best about the environment when it can access the same information through multiple senses. This benefits our perception by enhancing accuracy and precision. But if we want to make use of this perceptual benefit in vision rehabilitation, we need to know whether the blind brain actually learned to generate it.

It turns out that this depends on the age a person goes blind. Blindness before the age of eight or nine years influences how touch and hearing are used together to estimate object size. But blindness after this age impairs the ability to enhance perception through multisensory combination.

So what does that mean for sensory rehabilitation? We know that theres not one best solution for all, but we also know that the age of blindness-onset can provide important clues. If a person has been blind since birth or early childhood, the brain does not know how to process visual information, so vision restoration may not bring much benefit. If, however, sight was lost later in life, the brain is best wired to perceive its surroundings through vision.

But theres still good news for the congenitally and early blind: the enhanced perceptual abilities in the remaining senses can be used to substitute vision. In fact, visual information does not have to be taken up through the eyes it can also reach the brain through our other senses. In order for that to happen, it first needs to be translated into a different sensory language. For example, visual information can be directly translated into sound. Through training, the brain then learns to use this new sensory language, opening up the visual world through the use of another sense.

While sensory restoration advancements have come a long way, we are still far from an optimal solution that allows blind people to access visual information and equally partake in society. By realising that perception depends on individual experiences, we can better develop solutions that will most benefit each person whether that aims to restore their sight, or seeks to use their other senses instead.

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'Curing blindness': why we need a new perspective on sight rehabilitation - The Conversation UK

A Hungarian researcher has won theKrber Prize for European Science 2020 in Hamburg, Germany, earning him a1 million($1.18 million) check in the process.

Botond Roska, who works in the Swiss city of Basel, has uncovereda gene-based therapy that reprograms cells in the human eye so that they can perform the work of the light-sensitive receptors needed for human vision, according to the Krber Foundation that hands out the annual prize. It is hoped the procedure willreactivate the retinas of the blind.

Read more:India: Being blind during the coronavirus pandemic

The medical scientist said that, for the time being,the processcreates a level of vision similarto watching television in black and white. Clinical testson blind volunteers are already underway as a result of the Budapest-born researcher's groundbreaking work.

"Roska's research has woken up hope that new treatment methods might restore the ability to see in the blind,"said Hamburg Mayor Peter Tschentscher at theceremony on Monday.

The Krber Foundation's prize was first awarded in 1985, and it recognizesscientists whose work has applied futuristic techniques to physical sciences.

The son of a computer scientist and a pianist, Roska began his career in medicine "after a detour," said Tschentscher. The scientist first studied the cello at the Liszt Ferenc Academy of Music in Budapest, but had to give up the instrument following an injury. He thenbegan to pursue medicine and mathematics.

Last year's winner of the prestigious prize was German artificial intelligence scientistBernhard Schlkopf of the Max Planck Society.

jsi/dj (dpa, EPD)

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Hungarian researcher wins award for procedure that could cure blindness - DW (English)

Managing a broiler flock for top performance takes attention to detail. However, with many years of experience under the belt and knowledge of the inner workings of your farm, farm blindness is a point to consider.

You can only recognise an irregularity if you know what is normal. You will learn what is normal by observing as often and as objectively as possible. Always be aware of the dangers of farm blindness.

By definition farm blindness is when you see the situation on your own farm as the norm. Limit farm blindness by talking to colleagues and advisors on a regular basis and really share all critical and even sensitive data. Act on critical comments. Also go and look at other poultry keepers operations.

Join a study group to share opinions and ideas on a regular basis and improve together.

Find out more about African Swine Fever at our ASF section page

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PoultryWorld - How to prevent farm blindness? - Poultry World

Corneal blindness is the 4th most common type of blindness that affects the global population. However, it is also much easier to cure than many people might realise. In fact, with continued effort and research, this affliction might even be completely curable by 2035. Lets take a look at how this could come to pass.

Corneal blindness is described as a decrease in vision or even a complete loss of vision due to a disease of the cornea. There are several causes of this, including a vitamin A deficiency, eye trauma, or an infection of some sort.

Though it only affects 5% of the worlds blind population, it is still understandably devastating for those who have to live with this condition. It is also frequently found amongst populations that do not have the highest standard of living. If the main breadwinner of a family unit develops corneal blindness, it can have a massive knock-on effect for the rest of the family.

How Do We Treat Corneal Blindness?

Luckily, corneal blindness can be easier to treat than other types, and it can even fully restore someones sight to them. This is usually done with a corneal transplant. The cornea is the clear outer layer of your eye and it is an option for those who are filling out organ donor lists. Corneal transplants are one of the most common types of transplants that happen around the world.

Obviously, no transplant surgery can be described as cheap, and the people who need it the most often come from very poor areas or backgrounds. That is why the work of people like Tej Kohli and the Save Sight Registries are so important. They are helping those who need the treatment the most to get the help they need at no cost to them. It is a selfless pursuit, that could impact millions of lives.

How Do We Eradicate Corneal Blindness?

Treating corneal blindness is only the first step we need to take. It is also incredibly important that we put in plenty of steps to prevent further cases developing. Since corneal blindness is often caused by environmental factors, this can make it easier to do than something that could be primarily hereditary.

By making sure that people have a good standard of living at home and supplying PPE to dangerous worksites where the eye could be harmed, we will be able to prevent many cases of corneal blindness before they take root. This is incredibly important and could help to make numbers drop rapidly.

With this two-pronged attack between treatment and cause, we should see a decrease in the number of cases. This will soon put us well on the track to eradicating corneal blindness by 2035. Doing so will be a massive step forward in not just our lives but in medical science too. Who knows what we could learn as we fight to eradicate this illness throughout the world?

To find our more about theThe Tej Kohli Foundation visit their website http://www.tejkohlifoundation.com

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Can corneal blindness be eradicated by 2035? | HeraldScotland - HeraldScotland

Imagine trying to pass to a team-mate or avoid an opponent, but you can't because this is what you see...

From the grassroots to the highest professional level, colour blindness can impact the performance of players and coaches, spoil the enjoyment of watching sport (live or on TV), and affect commercial deals.

Kit clashes, coloured footballs under floodlights, signage and multi-coloured digital content can be problematic for people affected. A staggering one in 12 men suffer from colour blindness, and one in 200 women, amounting to a worldwide community of over 300 million people.

Despite this statistic, all too often colour blind fans find themselves unable to tell the teams apart, buy tickets independently or even see the ball.

Throughout the season, colour blind fans take to social media to vent their frustration and make the leagues and broadcasters aware of their ongoing oversight. In the Premier League during the last campaign, there were constant kit clashes being flagged up by viewers.

This is common across leagues around the world, and also in the international game. The same questions are asked of Fifa and Uefa during major tournaments, with many high-profile matches causing difficulty.

This is not just a problem for viewers, but players too.

Very few players are publicly colour blind, some due to lack of awareness, and others to avoid the risk of it damaging their chances of getting selected.

Coaches face similar issues, with equipment and training wear often invisible or difficult to distinguish between.

There is growing pressure on the key stakeholders, and some steps are beginning to be made to help raise awareness and consider colour blind people in all aspects of the game.

As far back as 2014, the FA Cup swapped its traditional white for a new pink Nike football, designed to be highly visible. However, it was clearly anything but, with colour blind people unable to distinguish the ball from the pitch.

After attracting fierce criticism from fans and commentators alike, the FA swapped back to a mainly white ball just a few months after release.

The FA has been active in campaigning and educating people ever since, releasing this animationexternal-link last year to give people an appreciation of the challenges faced by players and fans. In partnership with Uefa, it co-authored colour blindness guidelines that are now being adopted by more clubs and national associations.

Last season in the Premier League, Burnley were instructed by the Premier League not to wear their alternative green strip in their match against West Ham, prompting the release of a speedily designed, special edition white kit to avoid any clashes.

This weekend, Nations League matches will be the focal point for this year's Colour Blind Awareness Day (6 September), with many leading national associations and players participating in a campaign. Through a European Union-funded scheme run by Tackling Colour Blindness In Sport, the likes of Portugal and Manchester United's Bruno Fernandes and Iceland and Everton's Gylfi Sigurdsson have pledged their support.

"Not being able to watch a match on TV in full colour, to help easily distinguish between teams, referee cards and coloured objects in the stands seems almost unimaginable to me," said Fernandes.

"None of my team-mates has identified as colour blind but for sure there are many in football who may face a range of difficulties when playing or watching the game.

"That's why it's so important to raise awareness, provide greater information and make changes so that those who live with colour blindness don't feel left out and experience the game to the fullest."

Sigurdsson has experienced the issues first hand.

"I was at Reading's academy for many years with a colour blind player, Nicholas Bignall, who went on to play at a Premier League club. At the time I didn't realise he was colour blind and didn't appreciate until now how much more challenging training was for him if we used equipment he couldn't tell apart. This must have made it much more difficult to earn a place in the squad at times."

Matt Holland, best known for his time with Ipswich, Charlton and the Republic of Ireland, is an example of a player who had to deal with colour blindness while competing at the top level.

"Generally I was OK in games but occasionally struggled when the kits were quite close colour wise. The biggest challenge was having to take a split second longer to make a decision on where I was going to pass the ball to make certain I was passing to a team-mate."

"As a commentator now, I think it is imperative that colours of opposition sides are vastly different, and it would be helpful if the numbers on the back of shirts were more visible."

Despite ongoing kit clashes and social media frustrations, slow progress is clearly being made by the decision makers of football.

"The good news is that implementing procedures to assist and protect those with colour blindness in sport is relatively simple," said Kathryn Albany-Ward, founded of Colour Blind Awareness.

"Much of the time, all that's needed is a little goodwill and forward planning, and solutions can have positive benefits for teams, fans, sponsors and broadcasters."

Read this article:
Colour blindness in football: Kit clashes and fan struggles - what is being done? - BBC Sport

While you might be inclined to think that any hand sanitizer you pick up off a store shelf is safe to use, the sad reality is that some hand sanitizers have proven to be toxic, and in some instances, deadly. As weve highlighted previously, the FDA over the past few months has banned approximately 170 hand sanitizer brands due to the presence of methanol, a toxic substance that can cause a myriad of serious health complications.

Also known as wood alcohol, methanol has been found to cause seizures, permanent blindness, vomiting, and a range of other symptoms in users. In some tragic cases, it has even resulted in death when ingested by children.

Consumers who have been exposed to hand sanitizer containing methanol should seek immediate treatment which is critical for potential reversal of toxic effects of methanol poisoning, the FDA said in a letter a few months back.

Substantial methanol exposure can result in nausea, vomiting, headache, blurred vision, permanent blindness, seizures, coma, permanent damage to the nervous system or death, the statement adds.

Up until now, identifying potentially dangerous hand sanitizer brands has been somewhat easy given that nearly every offending brand was manufactured in Mexico. Recently, though, the FDA identified a dangerous hand sanitizer brand that was traced back to Florida.

As reported by the Miami Herald, a hand sanitizer brand manufactured by a Coral Gables company and distributed in Miami was found to contain methanol. The brand was quickly added to the FDAs banned list, a move which was accompanied by a recall.

AJR Trading recalled lot No. 20DF8307 of bio aaa Advance Hand Sanitizer in 480 ml bottles, expiration date April, 2022, after the FDA said its testing found methanol. Methanol, also known as wood alcohol, can be toxic if rubbed into the skin, according to the FDA.

The FDA adds that the company voluntarily recalled 2,004 units of the product due to the possible presence of methanol. Its worth noting that the company, to date, hasnt received any reports of users experiencing any adverse reactions to the product.

The FDA adds:

Consumers with questions regarding this recall can contact AJR Trading by phone insert 305-302-8416 or e-mail to ajrtrading15@gmaill.com Monday to Friday from 10:00 am to 5:00 pm Central Time. Consumers should contact their physician or healthcare provider if they have experienced any problems that may be related to taking or using this drug product.

A partial list of other banned hand sanitizer brands identified by the FDA can be seen below:

The full list of banned hand sanitizer brands can be viewed over here.

A life long Mac user and Apple enthusiast, Yoni Heisler has been writing about Apple and the tech industry at large for over 6 years. His writing has appeared in Edible Apple, Network World, MacLife, Macworld UK, and most recently, TUAW. When not writing about and analyzing the latest happenings with Apple, Yoni enjoys catching Improv shows in Chicago, playing soccer, and cultivating new TV show addictions, the most recent examples being The Walking Dead and Broad City.

Excerpt from:
The FDA just banned a toxic hand sanitizer made and distributed in the USA - BGR

From serving as a spokesperson for Foundation Fighting Blindness Canada, to becoming a motivational speaker, and then working full-time as an influencer with more than 2 million YouTube subscribers, Molly Burke is a force to be reckoned with. The 26-year-old also happens to be blind something she strives to educate the masses about in order to smash stereotypes and highlight societal barriers faced by the blind community.

But is Molly Burke fully blind? Keep reading to learn more.

Molly often gets bullied online because random strangers don't believe she's actually blind and the relentless misconceptions about people who are blind are often to blame.

In 2016, she published a YouTube video titled "Top 5 Reasons Why People on YouTube Think I'm Not Blind," during which Molly shared some people believe she's not fully blind because she can type. Except, as she pointed out in the video, there is an abundance of technology available to assist people with vision impairment / blindness to communicate (like talk-to-text, for example).

Another reason some are skeptical about Molly's blindness is because of the language she uses.

"For me, when I used the word 'watching,' obviously I don't mean physically watching with my eyes the way a sighted person would watch," she explained. "But for me, the word 'watching' means 'listening' it's interchangeable for me ... and yes, I'm still going to use the word 'watch,' and 'look,' and 'saw,' and 'see.' And that doesn't mean I'm faking my blindness."

Others mistakenly assume Molly must be able to see because her eyes don't appear to have anything physically "wrong" with them. "'You can't be blind, your eyes are blue,' or, 'You can't be blind, your eyes look normal,' or 'Your eyes are too pretty for you to be blind,'" are all comments she said she's fielded.

(For the record, Molly does have nystagmus, which causes her eyes to shake although it's not super noticeable.)

Here's another reason some people think Molly isn't actually blind: She's able to look directly at the camera.

"As a blind person, I'm still able to easily look at a camera because number one, it's not that hard to look straight forward, where the camera is straight ahead of you," she explained. "And number two, I use a ring light, which is a light that sits right on top of my camera and I have light perception, so I just look and see where the light is and then look directly below and know that is where my lens is. So that's where I have to look."

Still others wonder why Molly doesn't wear dark sunglasses if she's fully blind.

"This is a huge stereotype about the blind community that's not true," she said. "Yes, some blind people wear dark sunglasses when they're inside and outside. Yes, some blind people, including often myself, wear dark sunglasses when we're outside. And some blind people don't wear sunglasses ever, at all."

So yes, Molly Burke is truly, fully blind despite the fact that she doesn't wear sunglasses, doesn't have anything "wrong" with how her eyes physically appear, can type, can look into her camera lens, and uses phrases like "watching TV." And with the help of social media, she's working to continue smashing these stereotypes and more every day.

Original post:
Is Molly Burke Fully Blind? The Influencer Faces Regular Bullying - Distractify

In a letter dated August 13, 2020, Senators Ron Wyden and Jeff Merkley and Representatives Earl Blumenauer and Suzanne Bonamici, all of Oregon, requested that the EPA investigate the impact of tear gas use on people, air, land, and bodies of water.

LuizSouza / Shutterstock.com

The letter pointed out possible side effects the use of the chemicals might have, as well as potential long-term impacts.

In addition to the direct health impacts on our constituents, we are also deeply concerned about the impact tear gas has had on Oregons environment, the letter says. State and local environmental and health agencies are investigating its impacts, and it is also the duty of the Federal Government to provide information that will help further these studies and make information about the environmental impacts of tear gas usage readily available to the American public.

According to the Centers for Disease Control and Prevention, long-term exposure can cause blindness, glaucoma, immediate death from chemical burns and respiratory failure.

Tear gas is the generic term for a class of compounds that cause a burning sensation, according to a report by ProPublica. Most law enforcement agencies in the U.S., including the Philadelphia Police Department this week, use a chemical called CS, short for 2-chlorobenzalmalononitrile. CS activates a specific pain receptor, one thats also triggered by eating wasabi, said Sven-Eric Jordt, a professor of anesthesiology at Duke University. But CS is much more powerful, up to 100,000 times stronger than the sting from wasabi, he added.

They are really pain nerve gases, Jordt said. They are designed to induce pain.

Numerous medical and public health professionals have also noted that respiratory irritation from exposure to CS gas has the potential to increase the risk for COVID-19.

The Oregon state leaders sent the letter because Portland courthouse personnel were seen hosing tear gas off the sidewalks and streets around the courthouse after it was utilized as a riot control method. These chemicals were washed into storm drains and other groundwater sources.

The letter asks for the following specific information:

Because tear gas is often deployed as a method of riot control in all states and use of the gas has been widespread in many states in recent months, discovering the potential long-term impacts of the use of these chemicals is important.

Go here to read the rest:
Senators and Representatives Ask EPA to Study Impact of Tear Gas on Environment - EHS Daily Advisor

Photo: Alexi Rosenfeld/Getty Images

That wearing a mask is an effective way of reducing the spread of COVID-19 is well-established at this point. Both the Centers for Disease Control and Prevention and the World Health Organization recommend that people wear masks in public spaces where social distancing is not possible. That alone should be reason enough for you to mask up before walking out the door, but there is another possible benefit to wearing a face covering in public: not getting recognized by acquaintances on the street.

According to a new report from the New York Times, the widespread use of masks in the United States has made facial recognition increasingly difficult for many people in some cases, to an extent thats equivalent to having face blindness. In a recently published study, Dr. Erez Freud, a psychologist with the Centre for Vision Research at York University in Toronto, and his co-authors found that participants struggled to recognize faces that had surgical-style masks covering their noses and mouths. Of the nearly 500 adults who completed a facial-memory exercise online, 13 percent had so much trouble identifying masked faces that, per the Times, they may as well have suffered from prosopagnosia, or face blindness. Comparatively, only 3.5 percent scored that low in identifying people without masks.

A mask doesnt grant total anonymity, of course. Research has found that people rely most heavily on the eyes when identifying someone (I can personally confirm this: Once, I was pretty sure I saw Jake Gyllenhaal walking by my old office in Tribeca, but he was wearing sunglasses so I couldnt be 100 percent certain).

The report also found that the observers culture influenced their ability to perceive people wearing masks. Studies from 2009 and 2015 found that participants from Egypt and the United Arab Emirates countries where headscarves are more common were better than American or British participants at identifying faces where only the eyes, nose, and mouth were showing.

Struggling to identify faces can present real challenges in identifying and communicating with people (it can be more difficult to read peoples emotions, for example). Given that were all in the same boat right now, though, consider the possible upsides. Imagine, for instance, walking down the street by your apartment and constantly crossing paths with the guy you briefly dated who really tried to get you into the Joe Rogan Experience. Previously, youd both pretend to suddenly be consumed with something on your phones, and hurry past each other with heads bent. Now, you can both walk freely, spines straight, faces masked, blissfully unaware of each others presence, burdened only by absolutely every other terrible thing that is going on in the world. A dream!

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Its a Golden Age for Pretending Not to Notice Acquaintances on the Street - The Cut

Published 7:58pm EDT, Friday, September 4, 2020

Mr. Miles is an eight-year-old orange and white shorthair who is blind but he lives a pretty normal cat life. Mr. Miles also enjoys the company of others around him and he would do well living with other cats and dogs. Although he has not had much experience with children, he is a good cat and is willing to consider sharing his home with kids who can be gentle and respectful of pets. Mr. Miles definitely has lots of life to live and love to give. Please ask the adoption counselor to explain his blindness when you apply for a visit with Mr. Miles in Newington. Applications for adoption can be obtained at https://cthumane.org/adopt/all-adoptable-pets/. To learn more about operations during COVID-19, go to https://cthumane.org/adopt/adoption-process/.

Mr. Miles is an eight-year-old orange and white shorthair who is blind but he lives a pretty normal cat life. Mr. Miles also enjoys the company of others around him and he would do well living with other cats

Mr. Miles is an eight-year-old orange and white shorthair who is blind but he lives a pretty normal cat life. Mr. Miles also enjoys the company of others around him and he would do well living with other cats and dogs. Although he has not had much experience with children, he is a good cat and is willing to consider sharing his home with kids who can be gentle and respectful of pets. Mr. Miles definitely has lots of life to live and love to give. Please ask the adoption counselor to explain his blindness when you apply for a visit with Mr. Miles in Newington. Applications for adoption can be obtained at https://cthumane.org/adopt/all-adoptable-pets/. To learn more about operations during COVID-19, go to https://cthumane.org/adopt/adoption-process/.

Mr. Miles is an eight-year-old orange and white shorthair who is blind but he lives a pretty normal cat life. Mr. Miles also enjoys the company of others around him and he would do well living with other cats

Pet of the week: Mr. Miles

Mr. Miles is an eight-year-old orange and white shorthair who is blind but he lives a pretty normal cat life. Mr. Miles also enjoys the company of others around him and he would do well living with other cats and dogs. Although he has not had much experience with children, he is a good cat and is willing to consider sharing his home with kids who can be gentle and respectful of pets. Mr. Miles definitely has lots of life to live and love to give. Please ask the adoption counselor to explain his blindness when you apply for a visit with Mr. Miles in Newington. Applications for adoption can be obtained at https://cthumane.org/adopt/all-adoptable-pets/. To learn more about operations during COVID-19, go to https://cthumane.org/adopt/adoption-process/.

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Pet of the week: Mr. Miles - Torrington Register Citizen

Americas universities have been taken over by the Left, but the way they are reacting to the fake covid-19 crisis gives us a chance to reconstitute higher education on sound free market principles.

In the name of diversity, academic standards have been gutted. Here are some examples. Emily Walton, a sociology professor at Dartmouth, teaches her students about

white blindnessEveryone learns, but I find that the small handful of white students in the class usually learn the most. Thats because for the first time in their lives, they begin to look at themselves as members of a racial group. They understand that being a good person does not make them innocent but rather they, too, are implicated in a system of racial dominance.

After spending their young lives in a condition of white blindness,that is, the inability to see their own racial privilege, they begin to awaken to the notion that racism has systematically kept others down while benefiting them and other white people.

As Karen Kwiatkowski sums upthe situation: Imprisonment of speech and expression weve observed and lived this for decades as political correctness, maturing into blanking, canceling, me-tooing and doxxing the other. Strait-jacketing critical thought and destruction of the tools of debate, complete. Instead of looking forward we look at the fearful horde beside us and wonder what it is thinking and what direction it will take in order to inform our decisions which will be to conform with it, lest we become oblivion.

The brilliant young engineering student Atilla Mert Sulker points outthat the diversity poison has spread to the STEM (Science, Technology, Engineering, and Mathematics)disciplines:

The effort to close the gender gapin STEM represents a preference for minority status over merit that deems a students performance less important than her female-ness. Yet it only hurts individuals to put them in a field in which they will be unhappy or perform poorly, regardless of gender. If an individual, no matter how gifted, is averse to the risk of possibly burning out and forgoing a good grade, then maybe STEM isnt the right field.

STEM curricula are deliberately rigorous, as their subjects are not easy, and bridges tend to collapse when things go wrong. This is why there are weed-out classes to discourage students from pursuing them lightly.

As if this werent bad enough, many universities are imposing draconian restrictions on students to cope with covid-19. Jordan Schachtelhas written an important article about this. At Baylor University,

The university has announced that there will be weekly mandatory tests.If any student refuses to take the COVID-19 test, they are subject to suspension or expulsion. Students are not making friends with their classmates.No one can recognize whos who with a mask on, so there has been a significant increase of phone usage on campus and a significant decrease of socialization. Students show up for their in-person class, sit there, and head back to their apartment as soon as they are finished with classes. Everyone expects to move online before the semester is over. We all suspect that the university is postponing the move so that they can get the full tuition without much grounds for a lawsuit.

At the University of Iowa, They have isolation dorms for COVID kids, but they are horrid. Guys in hazmat suits come.2 week isolation, no visitors. Nurse on call but up to 3 hour wait if you need something.kids at school now are not getting tested so they dont get sentenced to the isolation prisons.

At St. Lawrence University, 1 positive case out of 2k tests. Kids limited to family groups and no more than four in dorm room. Masks when outside dorm and wrist band indicates you can go outdoors. Very limited social interaction.

At Creighton University,

11 days to get the required COVID test back. Isolated the whole time. No in person eating at the dorms as a norm. Training in the heat with masks for hours. Masks 24/7 on campus inside and out. Social isolation. 2 classes a week in person, everything else virtual. Cant come home until end of fall semester as you cant travel more than 100 miles from Omaha. Arent allowed to go anywhere or do anything except local restaurant pick ups and run to the store. If you are mildly exposed to a person with COVID, 14 day mandatory quarantine.

The universities will tell you that they need to impose these restrictions to cope with a raging pandemic, but they are lying. University students have almost no risk of dying from covid-19. Bill Sardi says, In the first 8 months of 2020 there were only ~1200 excess deaths per month or 40 extra deaths per day exclusively due to COVID-19 coronavirus infections, with 80% of those among Americans age 65 and older. By extrapolation, there were only ~8 excess COVID-19 only deaths per day among working-age adults and school-age children.

In order to understand what is happening to universities, we need to bear in mind something essential. The crisis did not begin with the diversity movement. After World War II, the government began a long-term effort to take over higher education. As Tom DiLorenzo has pointed out,

The damage caused by the program was much more than fiscal. It made the centralization of education possible for the first time in American history. That in turn opened the door to the ruinous politicization of higher education that has marked the past half century.

The tool used by government was the college accrediting agency.After the Second World War, the federal government used various college accrediting agencies to ostensibly guarantee a quality education for veterans. Only accredited schools could receive G.I. Bill funds, so the accrediting agencies quickly transformed themselves. They became the gatekeepers of the tax money and virtual adjuncts of federal power. This gatekeeper role expanded as federal funding of higher education escalated.This new world arrived almost immediately, as virtually every college and university in the country clamored for money and students, and willingly threw out traditional standards. This infusion of tax dollars created, notes Robert Nisbet, the single most powerful agent of change that we can find in the universitys long history.Had anyone objected at the time, he would have been put down as selfish and undemocratic.

Today, accreditation agencies, private in name only, have tremendous power over colleges and universities, and they are slavish to governments agenda. Today, these agencies are the major source of political correctness and big-government ideology on college campuses.

What can we do about this disaster? Karen Kwiatkowski is right. With the covid-19 restrictions, universities have gone too far. Students are fed up, and lawsuits for failing to fulfill contractual obligations may ruin many universities. She says,

One of the worst things that can happen to a state is to appear ridiculous.

Especially in the eyes of the young, who have had their expectations disappointed, their plans disrupted by mandate, their elders shown to be idiotic and frightened, their government greedy, avaricious, sadistic.

The state itself has assisted the liberty movement, with its lumbering broad-brush sadism. It far prefers physical destruction, marches and riots, police brutality and the outright rage of its citizens to the cuts of a thousand poems and 40 million awakening children who suddenly become aware that the King is buck naked, ugly, angry, vile, and simultaneously weak and wasted.

There is an additional reason we should view todays universities with skepticism, even if the leftists get tired of covid-19 and move on to some other craze. Tuition costs are enormous, and most students have to assume crippling loan burdens to get by. Today, roughly 70% of American students end up taking out loans to go to college. The average graduate leaves school with around $30,000 in debt and all told, some 45 million Americans owe $1.6 trillion in student loans and counting. Most of these loans cant be discharged through bankruptcy, and students may have to work decades to pay them off. What makes this even worse is that most of the tuition money goes into building lavish and unneeded buildings, perks for administrators, and diversity programs that undermine our culture. Die-versity is a better name for these programs.

The university was one of the foremost institutions of the High Middle Ages, and it is sad that the contemporary American university has sunk so low from the heights of medieval Oxford, Cambridge, Paris, and Salamanca. But we must face facts. What, then, can students and their parents who are fed up do? Private education and homeschooling are blossoming, creating a wide variety of choices for families and students.

I confess that one such alternative institution is foremost in my mind. A long-held vision of both Ludwig von Mises and Murray N. Rothbard is now a reality. Their vision? A graduate school of Austrian economics.

Throughout its nearly forty-year history, the Mises Institute has been focused on providing support to students of other educational institutions. Helping students discover the economics of freedom and inspiring them to go on to teach at the university level is and has been a priority for the Institute. Excellent service that is personal, responsive, and geared towardassisting students in reaching their individual educational and career goals has been emblematic of all Mises Institute programs.

At the Mises Institute, we aim to continue the tradition of education so eloquently expressed by Ludwig von Mises and Murray Rothbard, whowere among the highest exemplars of the values of Western civilization, and this is what we endeavor to transmit to our students.

More:
The Collapsing Universitiesand What We Can Do About It - The Shepherd of the Hills Gazette

Only 10 when his father died, Dr Hollows recalled being asked if he wanted to be an eye doctor like his dad. "I'd reply, 'I think I am going to finish school first'."

Dr Hollows initially avoided studying medicine, and became a marine biologist instead. But after he caught malaria in Papua New Guinea and saw how it ravaged young children, he retrained as a doctor.

Now 38, people still ask when he will become an ophthalmologist. "It is difficult, trying to keep up with a dead legend. I am a GP, but people still ask me if I want to be a eye doctor, and I can't think of anything more boring."

Like his older and younger sisters, Dr Hollows is also involved with the Fred Hollows Foundation to restore sight and prevent infectious diseases like trachoma that cause blindness. During the pandemic, its staff in Bangladesh and Pakistan used their knowledge of infection control to prevent the spread of COVID.

When Fred died, he received a state funeral and was buried in the bush in Bourke where he had worked every year. His wife Gabi went on to raise their five children under 10, and establish the non-profit that the couple envisaged before the ophthalmologist died.

Cam Hollows as a boy with his father Fred. Credit:Oliver Strewe

"They didn't see barriers, they saw a vision. They walked towards that, and sometimes it wasn't pretty," said the younger Dr Hollows.

Unlike most children who lose a parent and barely have a shoebox full of memories, Cam - who, like his sisters, was named by Fred in honour of left-wing revolutionaries - said he was lucky to have many photos and videos. "We have Fred's voice on tape, we also have the ongoing work of dad's that has kept the story alive, and kept the family together."

There are other reminders. Only last Thursday, a 90 year-old man walked into Dr Hollows' surgery with a photo he had taken at Fred's grave site in Bourke. Others tell him they travel to Bourke to have a whisky with Fred.

"My dad's grave is a tourist attraction," said Dr Hollows.

Now working in general practice in the Northern Rivers, Dr Hollows said he tries to live by his father's words: "I believe the basic attribute of mankind is to look after one another".

He works with a diverse range of people, from dairy farmers, who refused to seek help for broken bones, to the local Indigenous community.

Dr Hollows remembers Fred as the kind of father who took his kids camping, who thrashed him at chess, who stopped the car to force his children to climb boulders and read historical plaques, and took them out of school to travel with him.

"Fred was a carpenter, " said Dr Hollows. "He used to come home after a day of curing global blindness and would turn cedar furniture that would bring tears to your eyes."

Fred made his children a tree house that is only falling down now 30 years later. That's inspired the young Dr Hollows to make one for his two daughters, Matilda and Tabitha, with monkey bars, a swing and platform that would make any child happy.

He used to come home after a day of curing global blindness and would turn cedar furniture that would bring tears to your eyes.

Being a father is the most important thing most men can do, yet fathers - and those who fill these roles - can be torn in different directions, Dr Hollows said.

"It's tricky. In trying to look after and provide for our families, we don't necessarily get to spend as much time with our family doing the important stuff that we'd like because there's always another bill or another project.

"When dad married mum, he was quite a bit older and already had two older children, so he was able to write his own rules and spend time with us kids, get us to Nepal, get us to Bourke, build a tree house and get us down to Snowy Mountains. He was super active and engaged dad in the way many of us can't be," Cam said.

Most dads don't have the luxury of time or money to do that. Neither does Dr Hollows jnr, who is still paying off his HECS debts.

Julie Power is a senior reporter at The Sydney Morning Herald.

Original post:
Fred Hollows' son Cam on fatherhood: 'It's not about blood. It's about family' - Sydney Morning Herald

Vice President to address Virtually Valedictory of National Eye Donation Fortnight-2020

Make Netradhan a movement as strong as Pulse Polio

80lakh die every year, but, just 30,000 donate yes. Rest of the eyes are buried or burnt.

Hyderabad, September 07, 2020Vice President, Shri Venkaiah Naidu to address at the Valedictory Function Camba, a project of Saksham on National Eye Donation Fortnight-2020 on 8th September Virtually on Facebook, Instagram on other social media platforms ofsakshamseva.org. It will be held from 4.45 pm to 6 pm. It is an initiative of CAMBA. CAMBA is a project of SAKSHAM.

This idea behind this function is to Make NETRADAAN a movement as strong as Pulse Polio. India has more than twenty lakh cornea blind in India. The number is going upto to 35,000 to 40,000 every year. The burden of the disease is constantly on the rise.

80 lakh people die every year yet just 30,000 donate eyes, which is less than 1%. Not all the cornea collected can be used. Rest of the eyes are either buried or burnt. The collection must go up. If all those who die donates eyes, we can eradicate blindness from this country in just 5 years.

CAMBA stands for Cornea Andhatv Mukta Bharat Abhiyan (in Hindi). It means Corneal Blindness Free Bharat Movement (in English).

Another biggest challenge is the number of surgeons who are interested in the Cornea is not very high. Though there are 10,000 Opthalmologists in India, only 300 are practicing Cornea surgery. With the country with so much population, just 300 surgeons is very inadequate and the number must go up.

Cornea Andhatv Mukt Bharat Abhiyan (CAMBA) is a pan India movement of Saksham to bring down the incidence of Corneal Blindness in India and to motivate millions of Indians to pledge their eyes for this noble cause. Samadrishti, Kshamata Vikas Evam Anusandhan Mandal (SAKSHAM) is a charitable national organization with a major presence in Hyderabad.

CAMBA is a National Movement ignited by SAKSHAM, appeals to all the Ophthalmologists, Doctors Fraternity, Post Graduates, Medical Graduates, Eye Hospitals and all the Volunteers and People associated with eye care to join this momentous occasion and make NETRADAAN a movement as strong as Pulse Polio.

Every year more than 80 lakh people die in India but only 30 thousand people donate. That is less than 1%. We need at least 2 lakh pairs of the cornea to be donated every year to make Bharat Cornea blindness free in the next 5 years. Please join us to build New India as His Excellency, Honourable Vice President of India; Shri Venkaiah Naidu Ji joins the 35th National Eye Donation Fortnight Celebrations. Lets make India Corneal Blindness Free Donate Eyes, Live Twice.

What CAMBA does is the prevention of Corneal Blindness, Creates Awareness on Eye Donation. It educates government machinery about the gravity of the problem. It maintains a registry of Corneal Recipients; It encourages Eye Banks and Eye Collection Centres. It networks with good hearts.

Giving Light to the dark is gods mission said Dr. Abdul Kalam.

Read this article:
Vice President to address Virtually Valedictory of National Eye Donation Fortnight-2020 - IBG NEWS

Recent technological advances in the field of ophthalmology and the availability of new biomaterials have substantially expanded the range of potential application areas of contact lenses and enabled the development of novel prosthetic products

Roots Analysis is pleased to announce the publication of its recent study, titled, Next Generation Contact Lenses and Visual Prostheses Market, 2019-2030.

The report features an extensive study of the current market landscape of therapeutic contact lenses, drug-eluting contact lenses, diagnostic / monitoring contact lenses and visual prostheses. The study lays emphasis on the novel products and technologies that are being developed for the treatment of ocular disorders, which generally cause severe visual impairment or blindness. In addition to other elements, the study includes:

A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)

Type of Product

Type of Lenses

Target Indication

Key Geographical Region

Target Therapeutic Area

Transcripts of interviews held with the following senior level representatives of stakeholder companies:

Key companies covered in the report

For more information, please click on the following link:

https://www.rootsanalysis.com/reports/view_document/next-generation-contact-lenses-and-visual-prostheses-market-2019-2030/244.html

About Roots Analysis

Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If youd like help with your growing business needs, get in touch at [emailprotected]

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Link:
The Next Generation Contact Lenses and Visual Prostheses Market is estimated to be worth USD 3.7 billion in 2030, predicts Roots Analysis - Scientect

ISLAMABAD: The federal government is mulling to take immediate measures to promote coastal tourism in the country, as the development of Pakistans coastal areas could help the government earn $5 billion per annum.

According to the Maritime Study Forum, the government intends to develop coastal areas of Sindh and Balochistan and a study has already been conducted in this regard.

Pakistan hardly generates around $50,000 from this industry.

The forum recently conducted a survey wherein it was revealed that around 70pc of Pakistanis have either never experienced coastal tourism or had not seen Pakistans coastline beyond Karachi.

It suggested the federal and provincial governments of Sindh and Balochistan take immediate and concrete steps to promote coastal tourism and avert sea blindness.

As per Air Vice-Marshal (r) Ijaz Malik, Pakistan needs to learn from coastal tourism development models of countries that are exploiting the sectors potential. In this regard, he suggested the UAE model could help Pakistan develop its coast into a thriving tourism industry.

Meanwhile, senior journalist and anchorperson Nadia Naqi explained how Pakistans coastal tourism has remained stagnant through decades.

In order to promote coastal tourism, we not only need to develop infrastructure on coasts but also bring about sustainable development that protects the coastal ecosystem, she stated.

Naghmana Zafar, Senior Research Associate at NIMA, stressed the need to promote maritime domain awareness among institutions and organizations within the country. In order to address sea blindness in the country, the common public, as well as investors and institutions, need to be sensitised.

Moreover, Al-Noor Cruise Shipping CEO Shoaib Ahmed emphasized the importance of developing local coastal communities. He said the local culture of coastal communities can act as a great incentive to attract tourists towards this part of the country.

Maritime Study Forum President Dr Syed Mohammed Anwer also stressed the need for promoting maritime awareness in the country.

It will not only help to promote coastal development and tourism but will also highlight the importance of the overall maritime sector in the national economy.

He suggested the establishment of a coastal tourism authority to manage and promote coastal tourism in the country.

Go here to read the rest:
Govt mulls investing in coastal tourism to earn $5bn revenue per annum - Profit by Pakistan Today

8/24, StemoniX Inc.-Cancer Genetics Inc." Cancer Genetics and StemoniX have launched a joint proof-of-concept program to assess central nervous system (CNS) safety and toxicity of novel compounds.

8/25, Altivon LP-ConvergeOne: ConvergeOne, an IT-services provider of collaboration and digital infrastructure solutions, has acquired Altivon, a contact center solutions provider.

8/25, Emerson Resources Inc.-Pace Analytical Services: Pace Analytical Services has acquired Emerson Resources, a pharmaceutical contract development and manufacturing organization specializing in dosage form development and clinical trial material manufacturing.

8/26, Reardon Office Equipment-Loffler Cos. Inc.: Loffler Cos. has acquired Reardon Office Equipment to expand its market in North Dakota and northern Minnesota.

8/27, Collagen Solutions PLC-Rosens Diversified Inc.: Rosens Diversified, a food-production, agrochemical and distribution company, will acquire Collagen Solutions, a developer of medical-grade collagen, tissues and related devices and components for use in regenerative medicine, tissue engineering and research.

8/27, Open Systems International-Emerson Electric Co.: Emerson Electric will acquire Open Systems International, an operations technology software provider, for $1.6 billion.

8/28, Bluestem Brands Inc.-BLST Operating Co. LLC: BLST Operating Co., a privately held multibrand e-retailer, has acquired multibrand e-retailer Bluestem Brands.

Continued here:
Minnesota mergers and acquisitions - Minneapolis Star Tribune

VALENCIA, Calif. & MELBOURNE, Australia--(BUSINESS WIRE)--AVITA Therapeutics, Inc. (NASDAQ: RCEL, ASX:AVH), a regenerative medicine company that is developing and commercializing a technology platform that enables point-of-care autologous skin restoration for multiple unmet needs, announced today that management will participate in the following upcoming investor conferences.

Authorized for release by the Chief Executive Officer of AVITA Therapeutics, Inc.

ABOUT AVITA THERAPEUTICS, INC.

AVITA Therapeutics is a regenerative medicine company with a technology platform positioned to address unmet medical needs in burns, chronic wounds, and aesthetics indications. AVITA Therapeutics patented and proprietary collection and application technology provides innovative treatment solutions derived from the regenerative properties of a patients own skin. The medical devices work by preparing a RES REGENERATIVE EPIDERMAL SUSPENSION, an autologous suspension comprised of the patients skin cells necessary to regenerate natural healthy epidermis. This autologous suspension is then sprayed onto the areas of the patient requiring treatment.

AVITA Therapeutics first U.S. product, the RECELL System, was approved by the U.S. Food and Drug Administration (FDA) in September 2018. The RECELL System is indicated for use in the treatment of acute thermal burns in patients 18 years and older. The RECELL System is used to prepare Spray-On Skin Cells using a small amount of a patients own skin, providing a new way to treat severe burns, while significantly reducing the amount of donor skin required. The RECELL System is designed to be used at the point of care alone or in combination with autografts depending on the depth of the burn injury. Compelling data from randomized, controlled clinical trials conducted at major U.S. burn centers and real-world use in more than 8,000 patients globally, reinforce that the RECELL System is a significant advancement over the current standard of care for burn patients and offers benefits in clinical outcomes and cost savings. Healthcare professionals should read the INSTRUCTIONS FOR USE - RECELL Autologous Cell Harvesting Device (https://recellsystem.com/) for a full description of indications for use and important safety information including contraindications, warnings and precautions.

In international markets, our products are marketed under the RECELL System brand to promote skin healing in a wide range of applications including burns, chronic wounds and aesthetics. The RECELL System is TGA-registered in Australia and received CE-mark approval in Europe.

To learn more, visit http://www.avitamedical.com.

CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS

This letter includes forward-looking statements. These forward-looking statements generally can be identified by the use of words such as anticipate, expect, intend, could, may, will, believe, estimate, look forward, forecast, goal, target, project, continue, outlook, guidance, future, other words of similar meaning and the use of future dates. Forward-looking statements in this letter include, but are not limited to, statements concerning, among other things, our ongoing clinical trials and product development activities, regulatory approval of our products, the potential for future growth in our business, and our ability to achieve our key strategic, operational and financial goal. Forward-looking statements by their nature address matters that are, to different degrees, uncertain. Each forward- looking statement contained in this letter is subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statement. Applicable risks and uncertainties include, among others, the timing of regulatory approvals of our products; physician acceptance, endorsement, and use of our products; failure to achieve the anticipated benefits from approval of our products; the effect of regulatory actions; product liability claims; risks associated with international operations and expansion; and other business effects, including the effects of industry, economic or political conditions outside of the companys control. Investors should not place considerable reliance on the forward-looking statements contained in this letter. Investors are encouraged to read our publicly available filings for a discussion of these and other risks and uncertainties. The forward-looking statements in this letter speak only as of the date of this release, and we undertake no obligation to update or revise any of these statements.

Continued here:
AVITA Therapeutics to Participate in Upcoming Investor Conferences - Business Wire

Rheumatoid Arthritis Stem Cell Therapy Market: Outlook

Regenerative medicine has made extensive advancements over the years to cure the populace of certain disorders or diseases. Stem cell therapy is a category of regenerative medicine that has gained considerable traction over the years as an efficient treatment option for a plethora of disorders including rheumatoid arthritis. Therefore, the global rheumatoid arthritis stem cell therapy market will bank on the efficacy of bringing rheumatoid arthritis in control across the forecast period of 2020-2030.

Based on treatment type, the global rheumatoid arthritis stem cell therapy market can be classified into bone marrow transplant, Allogeneic Mesenchymal stem cells, and adipose tissue stem cells. On the basis of the distribution channel, the rheumatoid arthritis stem cell therapy market can be segmented into ambulatory surgical centers, specialty clinics, and hospitals.

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This upcoming research report by Transparency Market Research on the rheumatoid arthritis stem cell therapy market enlightens the stakeholder about numerous aspects such as competitive landscape, geographical analysis, current and upcoming trends, and others. The report also sheds light on the pain points and helps the stakeholder in preparing efficient business strategies to overcome them.

The report also covers the changing dynamics of growth across the rheumatoid arthritis stem cell therapy market due to the novel coronavirus outbreak. The researchers have analyzed every small aspect of the COVID-19 impact and then added them in the report.

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Rheumatoid Arthritis Stem Cell Therapy Market: Competitive Landscape

The rheumatoid arthritis stem cell therapy market can be categorized as highly fragmented due to the presence of numerous players competing for the top position. Research and development activities form an important part to discover novel insights across varied rheumatoid arthritis stem cell therapy mechanisms.

Some well-established participants in the rheumatoid arthritis stem cell therapy market are International Stem Cell Corporation, Mesoblast Ltd., Regeneus Ltd, International Stem Cell Corporation, ReNeuron Group plc, and TiGenix.

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Rheumatoid Arthritis Stem Cell Therapy Market: Growth-Inducing Advantages

Many advantages are attached to the rheumatoid arthritis stem cell therapy market that helps in bringing extensive growth opportunities. Although rheumatoid arthritis stem cell therapy is not a full-proof treatment for curing arthritis, it can reduce inflammation and also aid in the stabilization of the immune system. In addition, the rheumatoid arthritis stem cell therapy has also shown long-term efficacy in overcoming inflammation caused due to arthritis. Government support is also proving to be a major growth factor for the rheumatoid arthritis stem cell therapy market.

Furthermore, research has also highlighted the improvement in sleep, diet, and physical strength among the patients after cell therapy.

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Rheumatoid Arthritis Stem Cell Therapy Market: Key Findings

The research and development activities in the rheumatoid arthritis stem cell therapy market are always in full swing and are involved in exploring novel findings that help in increasing the graph of growth. For instance, scientists recently discovered a new cell, known as PRIME cell that appears in the bloodstream of rheumatoid arthritis patients just before the inflammation begins. Such findings may help the players in the rheumatoid arthritis stem cell therapy market to discover novel mechanisms of rheumatoid arthritis stem cell therapy.

Rheumatoid Arthritis Stem Cell Therapy Market: Geographical Analysis

The rheumatoid arthritis stem cell therapy market can be geographically segmented into North America, Latin America, the Middle East and Africa, Asia Pacific, and Europe. North America may emerge as a champion growth contributor for the rheumatoid arthritis stem cell therapy market during the forecast period of 2020-2030. The presence of numerous key players in the region can serve as a major growth factor.

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Rheumatoid Arthritis Stem Cell Therapy Market Business Opportunities and Growth Challenges Report - The Daily Chronicle

The paper

C. Tipton et al., Patient genetics is linked to chronic wound microbiome composition and healing, PLOS Pathog, 16:e1008511, 2020.

How quickly scrapes, cuts, and gashes in the skin heal can vary greatly depending on a persons body mass, age, and whether the individual suffers from certain chronic conditions such as diabetes. Genetics, a new study suggests, may also play a role, with variations in two specific genes lowering the diversity of a wounds microbiome and lengthening healing time.

Through a partnership with Southwest Regional Wound Care Center in Lubbock, Texas, geneticist Caleb Phillips at Texas Tech University and colleagues gained access to 85 patients DNA samples. Analyzing each persons sample and comparing it to the diversity of bacteria in the patients infected wound, the team found that individuals with specific single nucleotide polymorphisms (SNPs) in TLN2, a gene involved in actin assembly, and ZNF521, which encodes a transcription factor, had lower overall microbial diversity in their wounds and were much more likely to suffer from Pseudomonas and Staphylococcus infections. Those patients skin injuries were also much slower to heal, suggesting that individuals with these specific TLN2 and ZNF521 mutations may be at higher risk of developing chronic wounds.

Despite the modest sample size, Phillips says, the study offers a better understanding of what makes a patient vulnerable to chronic wounds. The SNPs the team described in TLN2 and ZNF521 could serve as biomarkers to identify patients at risk for slow wound recovery, he notes.

The extent of the microbiomes role in chronic wounds is a really big question in the field of healing and repair, notes Lindsay Kalan, a medical microbiologist and immunologist at the University of WisconsinMadison who was not involved in the study. While the papers results are not immediately translatable for patient care, she says, it is definitely a step in the right direction.

Link:
Long-Lasting Wound Infections Linked to Microbes and Genetics - The Scientist