StemCell Therapy

A promising therapy for heart attacks uses stem cells to repair the damaged areas of the heart. However, getting the transplanted cells to stay at the site is a challenge. Now scientists have created a new type of off-the-shelf cardiac patch that overcomes these limitations.

The leading cause of death in the United States is coronary heart disease, which kills about 360,000 per year. Heart attacks result from the loss of blood flow to part of the heart muscle. This can be caused by fat, cholesterol and other substances forming plaque in the coronary arteries that supply oxygenated blood to the heart.

When the plaque breaks, a clot forms around it, which can prevent blood flow to a part of the heart and kill cells. The degree of damage depends on the area of the heart supplied by the blocked artery.

Treatments for a heart attack include limiting the original damage and blocking the secondary damage, which reduces long-term consequences and saves lives. As the heart heals, the damaged area forms scar tissue, which cannot pump blood like normal heart tissue, and it can affect the performance of the rest of the heart.

Cell therapy for heart attacks involves using cardiac stromal cells to encourage the heart to heal with muscle cells rather than scar tissue. Cardiac stromal cells interact with muscle cells and release chemical signals to encourage muscle cell growth.

This approach has only moderate benefits, because cardiac stromal cells are fragile and must be carefully stored and transported. Making matters worse, some stem cells can grow out of control and become tumors. Using a patients own cells has some advantages, but its expensive and time consuming. Theres also the problem of preventing the beating heart from washing the cells away.

Several types of scaffolds have been developed to keep the cardiac stromal cells at the proper location. However, these scaffolds dont overcome the cost and difficulties of isolating and expanding the stem cells.

Now a group of scientists has created a new type of artificial cardiac patch. It consists of a scaffolding matrix made from pig cardiac tissue, from which all cells have been removed. They then created artificial cardiac stromal cells by putting the important healing components from cardiac stromal cells into biodegradable microparticles within that matrix. The synthetic cardiac stromal cells mimic the therapeutic features of live stem cells while overcoming their storage and survival problems, and the matrix preserves the structures and activity found in cardiac tissue.

The artificial cardiac patch was shown to hold the synthetic cardiac stromal cells in place on the heart. In heart attack experiments in both rodents and pigs, the patch resulted in a 50 percent improvement in heart function and a 30 percent reduction in scarring when compared to no treatment.

Medical Discovery News is hosted by professors Norbert Herzog at Quinnipiac University, and David Niesel of the University of Texas Medical Branch. Learn more at http://www.medicaldiscoverynews.com.

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Heart attack patches may save lives in US and beyond - Galveston County Daily News

Acquisition to support accelerated commercialization of Koligos KYSLECEL,a personalized islet cell therapy available in the U.S. for chronic and recurrent acute pancreatitis

Goal to rapidly advance KT-PC-301, an autologous cell therapy under investigationfor the treatment of COVID-19-related Acute Respiratory Disease Syndrome (ARDS)

Orgenesis to leverage Koligos 3D-V bioprinting technology across its POCare Platform

GERMANTOWN, Md., Sept. 29, 2020 (GLOBE NEWSWIRE) -- Orgenesis Inc. (NASDAQ: ORGS) (Orgenesis or the Company), a global biotech company working to unlock the full potential of cell and gene therapies, and Koligo Therapeutics, Inc. (Koligo), a regenerative medicine company, today announced that the two companies have entered into a definitive merger agreement, subject to final closing conditions, with expected completion before year-end (Transaction).

Koligo is a leader in developing personalized cell therapies utilizing the patients own (autologous) cells. Koligo has successfully launched its first commercial product, KYSLECEL, and plans to commence a phase 2 trial of KT-PC-301 for COVID-19-related ARDS. Koligos development stage technology utilizes 3D bioprinting and vascularization with autologous cells (3D-V technology) to create biodegradable and shelf-stable three-dimensional cell and tissue implants. The 3D-V technology is being developed for diabetes and pancreatitis, with longer term applications for neural, liver, and other cell/tissue transplants.

Following closing of the Transaction, Orgenesis plans to accelerate the commercial scaleup of KYSLECEL throughout the United States and, subject to regulatory and logistical considerations, in international markets as well. After closing of the Transaction, and subject to FDA review and clearance of the Companys Investigational New Drug application, Orgenesis expects to start patient recruitment for a phase 2 randomized clinical trial of KT-PC-301 in COVID-19 patients. Orgenesis also plans to leverage Koligos 3D-V bioprinting technology across its POCare platform.

Under the terms of the merger agreement, Orgenesis will acquire all of the outstanding stock of Koligo from its shareholders (the founders and staff of Koligo and a subsidiary of Bergen Special Opportunity Fund, LP, an institutional investor managed by Bergen Asset Management, LLC). The agreed consideration terms are an aggregate of $15 million in shares of Orgenesis common stock valued at $7.00 per share which shall be issued to Koligos accredited investors (with certain non-accredited investors to be paid solely in cash) and an assumption of $1.3 million in Koligos liabilities, estimated to be substantially all of Koligos liabilities. Additional details of the Transaction will be available in the Companys Form 8-K, which will be filed with the Securities and Exchange Commission, and will be available at http://www.sec.gov.

KYSLECELKoligos KYSLECEL is commercially available in the United States for chronic and recurrent acute pancreatitis in a surgical procedure commonly called Total Pancreatectomy with Islet Autologous-Transplant (TPIAT). TPIAT has been proven to provide significant pain relief, improved quality of life, and a reduction in the need for pain medication for patients suffering from chronic or recurrent acute pancreatitis. KYSLECEL infusion after a total pancreatectomy helps preserve insulin secretory capacity and reduce the risk of diabetic complications. KYSLECEL is made from a patients own pancreatic islets the cells that make insulin to regulate blood sugar.

Koligo has commenced its commercial pilot program for KYSLECEL at six U.S. hospitals, treating 40 patients to date. The KYSLECEL pilot program has generated approximately $2 million in sales revenue. KYSLECEL has also been shown to result in significant savings to payors over traditional chronic pancreatitis management. Following the closing of the Transaction, Orgenesis plans to make KYSLECEL available to an increasing number of hospitals throughout the United States through its POCare Network.

KT-PC-301Koligos lead clinical development program is for KT-PC-301, an autologous cell therapy under investigation for the treatment of COVID-19-related Acute Respiratory Disease Syndrome (ARDS). KT-PC-301 is comprised of autologous stromal and vascular fraction cells (SVF) derived from each patients adipose (fat) tissue. KT-PC-301 contains a population of mesenchymal stem cells, vascular endothelial cells, and immune cells which migrate to the patients lungs and other peripheral sites of inflammation. Nonclinical and clinical evidence demonstrate that KT-PC-301 may: (1) stabilize microcirculation to improve oxygenation; (2) maintain T and B lymphocytes to support antibody production; and (3) induce an anti-inflammatory effect.

Koligo has completed a pre-IND (Investigational New Drug) consultation with the U.S. Food and Drug Administration to start clinical trials of KT-PC-301 in COVID-19-related ARDS. Following the closing of the Transaction, and subject to FDA review and clearance of the Companys Investigational New Drug application, Orgenesis expects to start patient recruitment for a phase 2 randomized clinical trial of KT-PC-301 in COVID-19 patients. As currently planned, the phase 2 trial is expected to enroll 75 patients and evaluate the safety and efficacy of KT-PC-301. Mohamed Saad, MD, Chief of Division of Pulmonary, Critical Care, and Sleep Disorders Medicine at the University of Louisville, will be the lead clinical investigator on the trial.

3D-V Technology Koligos 3D-V bioprinting technology is designed to support development of a number of product candidates for the treatment of diabetes, cancer, neurodegenerative disease, and other serious diseases. The 3D-V technology platform is able to print three-dimensional cell and tissue constructs with a vascular network. Key benefits of the 3D-V approach include: faster revascularization/inosculation of cell/tissue transplant to improve engraftment; host tolerance of the graft while minimizing need for immune suppressive drugs; better site of transplant administration of such products; and scaffolding to keep cell/tissue in place in vivo. These solutions are ideally suited for islet transplant and other cell/tissue transplant applications.

Koligo ManagementFollowing the closing of the Transaction, Koligos management team will be joining Orgenesis to continue commercial and development activities. Koligos CEO, Matthew Lehman, is an accomplished executive in the biotech and regenerative medicine fields. Prior to co-founding Koligo, he was CEO of Prima Biomed Ltd (now Immutep Ltd, a Nasdaq (IMMP) and ASX (IMM) listed biotech company). Stuart Williams, PhD, Chief Technology Officer, is a bioengineer and thought leader in regenerative medicine, with over 300 publications and 20 issued patents in the field. Dr. Williams has co-founded three other biotech companies and is an experienced academic-industry collaborator. Michael Hughes, MD, Chief Medical Officer, is a transplant surgeon who started the islet transplant program at University of Louisville which was the genesis of Koligos KYSLECEL program. He has successfully treated nearly 50 chronic pancreatitis patients with islet autologous transplant after pancreatectomy. Balamurugan Appakalai, PhD, has more than 20 years of islet isolation experience, having processed more than 800 human pancreases. He is a leader in the field of islet transplant with 100+ publications.

Vered Caplan, Chief Executive Officer of Orgenesis, stated, We are pleased to announce this transformative acquisition, which we expect will add broad capabilities to our therapeutic and technology platform, and will further our leadership in the cell and gene therapy field. Based on several phase 1 studies, Koligos KT-PC-301, using a patients own cells, has demonstrated safety and tolerability, and has shown signs of efficacy to support continued development in COVID-19-related ARDS. If successful for the treatment of COVID-19-related ARDS, KT-PC-301 is likely to have applications in other acute and chronic respiratory indications, areas that represent significant unmet medical need. In addition, we see significant potential in KYSLECEL, a commercial stage asset for the treatment of chronic and acute recurrent pancreatitis, which we plan to introduce through our global network of hospitals. Finally, Koligos 3D-V bioprinting technology is highly complementary to our POCare Platform, as we implement new technologies to improve efficacy and lower the costs of cell and gene therapies. I would like to personally welcome Matthew and the rest of the Koligo team to the Orgenesis organization when the Transaction closes. We believe that their skills and experience will be an important addition as we execute on our strategy to unlock the power of cell and gene therapies and make them accessible to all.

Matthew Lehman, Chief Executive Officer of Koligo Therapeutics, stated, The merger with Orgenesis marks a major milestone for our company and builds on our recent progress, including the Pre-IND package submitted to the U.S. FDA for KT-PC-301 and our pilot commercial program for KYSLECEL. The Orgenesis team brings extensive clinical, regulatory, and manufacturing expertise well suited to supporting Koligos goals. Orgenesis intellectual property is highly complementary to Koligos technology and the combined companies will work to advance a robust commercial and development product portfolio. Orgenesis POCare technologies are also ideally suited for low-cost and efficient production of autologous cell therapies at the point of care, which we believe will considerably enhance the delivery of these therapies to patients. Additionally, we believe Orgenesis global network of leading hospitals and healthcare institutions will enable us to accelerate the commercial rollout of KYSLECEL. We are quite encouraged by the outlook for the business and look forward to leveraging Orgenesis POCare Platform in order to accelerate the timeline to bringing our innovative cell therapies to market. Through this merger, we believe we can maximize value for all shareholders and we are grateful to Orgenesis for this opportunity.

Pearl Cohen Zedek Latzer Baratz LLP and KPMG advised Orgenesis on the Transaction. Maxim Group LLC acted as a finder and Nelson Mullins Riley & Scarborough, LLP advised Koligo on the Transaction.

About Koligo Therapeutics Koligo Therapeutics, Inc. is a US regenerative medicine company. Koligos first commercial product is KYSLECEL (autologous pancreatic islets) for chronic and acute recurrent pancreatitis. Koligos 3D-V technology platform incorporates the use of advanced 3D bioprinting techniques and vascular endothelial cells to support development of transformational cell and tissue products for serious diseases. More information is available at http://www.koligo.net.

About OrgenesisOrgenesis is a global biotech company working to unlock the full potential of celland gene therapies (CGTs) in an affordable and accessible format at the point of care. The Orgenesis POCarePlatform is comprised of three enabling components: a pipeline of licensedPOCare Therapeuticsthat are processed and produced in closed, automatedPOCare Technologysystems across a collaborativePOCare Network. Orgenesisidentifies promising new therapies and leverages its POCare Platform to provide a rapid, globally harmonized pathway for these therapies to reach and treat large numbers of patients at lowered costs through efficient, scalable, and decentralized production. The Network brings together patients, doctors, industry partners, research institutes and hospitals worldwide to achieve harmonized, regulated clinical development and production of the therapies. Learn more about the work Orgenesis is doing atwww.orgenesis.com.

Notice Regarding Forward-Looking Statements The information in this release is as of September 29, 2020. Orgenesis assumes no obligation to update forward-looking statements contained in this release as a result of new information or future events or developments. This release contains forward looking statements about Orgenesis, Koligo, Koligos technology, and potential development and business opportunities of Koligo and Orgenesis following the closing of the Transaction, each of which involve substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. Risks and uncertainties include, among other things, uncertainties regarding the commercial success of the Companys products; the uncertainties inherent in research and development, including the ability to meet anticipated clinical endpoints, commencement and/or completion dates for our clinical trials, regulatory submission dates, regulatory approval dates and/or launch dates, as well as the possibility of unfavorable new clinical data and further analyses of existing clinical data; the risk that clinical trial data are subject to differing interpretations and assessments by regulatory authorities; whether regulatory authorities will be satisfied with the design of and results from our clinical studies; whether and when any such regulatory authorities may approved the Companys development products, and, if approved, whether such product candidates will be commercially successful; decisions by regulatory authorities impacting labeling, manufacturing processes, safety and/or other matters that could affect the availability or commercial potential of the Companys products; uncertainties regarding the impact of COVID-19 on the Companys business, operations and financial results and competitive developments.

A further description of risks and uncertainties can be found in the Companys Annual Report on Form 10-K for the fiscal year ended December 31, 2019 and in its subsequent reports on Form 10-Q, including in the sections thereof captioned Risk Factors and Forward-Looking Information, as well as in its subsequent reports on Form 8-K, all of which are filed with the U.S. Securities and Exchange Commission and available at http://www.sec.gov.

Contact for Orgenesis:Crescendo Communications, LLCTel: 212-671-1021ORGS@crescendo-ir.com

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Orgenesis Announces Agreement to Acquire Koligo Therapeutics, a Leader in Personalized Cell Therapies - GlobeNewswire

Bariatric surgery, a significantly underutilized treatment for weight management, is beginning to see an uptick in usea trend spurred by a somewhat unlikely cause: the novel coronavirus epidemic.

The 3 most important considerations for patients deciding on bariatric surgery

According to the New York Times' "Well," bariatric surgery is an increasingly safe, effective, and simple procedure available to patients with a BMI of at least 40 who cannot lose weight via diet and exercise alone, as well as patients with BMIs between 30 to 35 who have obesity-related health issues.

Bariatric surgeriesincluding gastric bypasses, laparoscopic bands, and gastric sleeveswork by reducing the physical size of the stomach and curbing appetite by altering the hormonal signals between a patient's stomach and brain. Bariatric surgery, according to "Well," has become increasingly safe over the years, with the rates of complications and deaths related to such procedures plunging from a peak of 11.7% and 1%, respectively, in 1998 to 1.4% and 0.04% in 2016.

However, despite the safety and efficacy of the procedure, experts say it's significantly underutilized. "Only one-half of 1 percent of people eligible for bariatric surgery currently undergo it," Anne Ehlers, a bariatric surgeon at the University of Michigan, said.

According to a JAMA article, this under-use of bariatric surgery likely stems both from "the reluctance of the medical community and patients to accept surgery as a safe, effective, and durable treatment of obesity," and because patients worry that they "may be judged by others for taking the easy way out and not having the willpower to diet and exercise."

According to the Wall Street Journal, several studies have found a link between obesity and its related health issuessuch as diabetes and hypertensionand increased rates of serious Covid-19 infection. In fact, CDC this month confirmed that new research demonstrates that Covid-19 patients who are obese have a greater risk of severe outcomes.

Researchers think this increased risk for obese patients may stem in part because of how the coronavirus enters the body via an enzyme called the ACE2 receptor. This enzyme is located in cells that line the lungs and fat tissue, which means that patients with excess weight may be more likely to experience a high viral load. In addition, obesity is linked to hyperinflammation and shortness of breath, two conditions that make it more difficult for someone to combat viral infection.

As John Morton, head of the bariatric practice at Yale Medical Center, said, "The virus frankly has an easier job" replicating itself among patients who are obese, because "[i]t has more targets."

But ongoing research indicates that losing weightand losing weight via bariatric surgery in particularmay help lower this risk, the Journal reports. According to a clinical study from the Cleveland Clinic that's currently under peer review, patients with obesity who've had bariatric surgery were 25% less likely to require hospitalization after contracting Covid-19 when compared with obese patients who have not had the surgery. In addition, among those patients in the study who were hospitalized, none of those who've had bariatric surgery were admitted to the ICU or died from the pathogencompared with 13% and 2.5%, respectively, of hospitalized patients who have not had the surgery.

In light of this increased risk, some patients who are struggling with their weight are undergoing bariatric surgery as a proactive measure against severe infectiona trend that seems to have made bariatric surgery more popular than ever, the Journal reports.

In fact, while most scheduled procedures are now experiencing a rebound after several months' pause amid the epidemic, bariatric surgery is not only rebounding more quickly than other services, but it's surpassing even its 2019 levels. Specifically, according to research from health care data company Perception Health, claims for bariatric surgery fell to nearly zero in April, but then rebounded by June to a higher level than that same month in 2019.

Separately, Optum, which owns medical facilities and surgical centers across the country, reported a 26% annual increase in patients joining bariatric-surgery programs this summer. (The Daily Briefing is published by Advisory Board, a division of Optum.) Similarly, Cigna said that while prior authorizations for bariatric surgeries declined 38.8% annually between March and May of this year, they increased 9.3% annually in June, July, and August.

The leaders of various surgical practices at major hospitals have reported similar anecdotal evidence, according to the Journal. For instance, Morton said that after Yale reopened its five hospitals for scheduled surgeries in June, bariatric surgery volume increased 20% when compared to 2019 levelsand inquiries about the procedure are also on the rise. "The only two surgeries that have been Covid-proof have been cancer and bariatric," he said.

Similarly, Ali Aminian, director of the Cleveland Clinic's Bariatric and Metabolic Institute, said intake for severely obese patients seeking bariatric surgery increased 40% annually over the summer. "We've had patients who wanted to come and take care of their obesity, to be healthier, and when we ask them, why did you come now? It's because they've heard this message that it's a risk factor for Covid infection," Aminian said.

And speaking as a bariatric surgery patient, Eliza Henderson said the coronavirus spurred her to "take the plunge" and schedule herself for the procedure later this month. "I don't want my being obese to stack the odds against me with something like coronavirus," Henderson explained. "More than anything, I want to have a better chance to survive" (Whelan, Wall Street Journal, 9/28; Brody, "Well," New York Times, 9/28).

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Bariatric surgery is booming, as obese patients worry about their Covid-19 risks - The Daily Briefing

Global Stem Cell Reconstructive Marketwas valued US$ XX Mn in 2019 and is expected to reach US$ XX Mn by 2027, at a CAGR of 24.5% during a forecast period.

Market Dynamics

The Research Report gives an in-depth account of the drivers and restraints in the stem cell reconstructive market. Stem cell reconstructive surgery includes the treatment of injured or dented part of body. Stem cells are undifferentiated biological cells, which divide to produce more stem cells. Growing reconstructive surgeries led by the rising number of limbs elimination and implants and accidents are boosting the growth in the stem cell reconstructive market. Additionally, rising number of aged population, number of patients suffering from chronic diseases, and unceasing development in the technology, these are factors which promoting the growth of the stem cell reconstructive market. Stem cell reconstructive is a procedure containing the use of a patients own adipose tissue to rise the fat volume in the area of reconstruction and therefore helping 3Dimentional reconstruction in patients who have experienced a trauma or in a post-surgical event such as a mastectomy or lumpectomy, brain surgery, or reconstructive surgery as a result of an accident or injury. Stem cell reconstructive surgeries are also used in plastic or cosmetic surgeries as well. Stem cell and regenerative therapies gives many opportunities for development in the practice of medicine and the possibility of an array of novel treatment options for patients experiencing a variety of symptoms and conditions. Stem cell therapy, also recognised as regenerative medicine, promotes the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives.

The common guarantee of all the undifferentiated embryonic stem cells (ESCs), foetal, amniotic, UCB, and adult stem cell types is their indefinite self-renewal capacity and high multilineage differentiation potential that confer them a primitive and dynamic role throughout the developmental process and the lifespan in adult mammal.However, the high expenditure of stem cell reconstructive surgeries and strict regulatory approvals are restraining the market growth.

The report study has analyzed revenue impact of covid-19 pandemic on the sales revenue of market leaders, market followers and disrupters in the report and same is reflected in our analysis.

Global Stem Cell Reconstructive Market Segment analysis

Based on Cell Type, the embryonic stem cells segment is expected to grow at a CAGR of XX% during the forecast period. Embryonic stem cells (ESCs), derived from the blastocyst stage of early mammalian embryos, are distinguished by their capability to distinguish into any embryonic cell type and by their ability to self-renew. Owing to their plasticity and potentially limitless capacity for self-renewal, embryonic stem cell therapies have been suggested for regenerative medicine and tissue replacement after injury or disease. Additionally, their potential in regenerative medicine, embryonic stem cells provide a possible another source of tissue/organs which serves as a possible solution to the donor shortage dilemma. Researchers have differentiated ESCs into dopamine-producing cells with the hope that these neurons could be used in the treatment of Parkinsons disease. Upsurge occurrence of cardiac and malignant diseases is promoting the segment growth. Rapid developments in this vertical contain protocols for directed differentiation, defined culture systems, demonstration of applications in drug screening, establishment of several disease models, and evaluation of therapeutic potential in treating incurable diseases.

Global Stem Cell Reconstructive Market Regional analysis

The North American region has dominated the market with US$ XX Mn. America accounts for the largest and fastest-growing market of stem cell reconstructive because of the huge patient population and well-built healthcare sector. Americas stem cell reconstructive market is segmented into two major regions such as North America and South America. More than 80% of the market is shared by North America due to the presence of the US and Canada.

Europe accounts for the second-largest market which is followed by the Asia Pacific. Germany and UK account for the major share in the European market due to government support for research and development, well-developed technology and high healthcare expenditure have fuelled the growth of the market. This growing occurrence of cancer and diabetes in America is the main boosting factor for the growth of this market.

The objective of the report is to present a comprehensive analysis of the Global Stem Cell Reconstructive Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that includes market leaders, followers and new entrants. PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors of the market has been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analysed, which will give a clear futuristic view of the industry to the decision-makers.

The report also helps in understanding Global Stem Cell Reconstructive Market dynamics, structure by analysing the market segments and projects the Global Stem Cell Reconstructive Market size. Clear representation of competitive analysis of key players by Application, price, financial position, Product portfolio, growth strategies, and regional presence in the Global Stem Cell Reconstructive Market make the report investors guide.Scope of the Global Stem Cell Reconstructive Market

Global Stem Cell Reconstructive Market, By Sources

Allogeneic Autologouso Bone Marrowo Adipose Tissueo Blood Syngeneic OtherGlobal Stem Cell Reconstructive Market, By Cell Type

Embryonic Stem Cell Adult Stem CellGlobal Stem Cell Reconstructive Market, By Application

Cancer Diabetes Traumatic Skin Defect Severe Burn OtherGlobal Stem Cell Reconstructive Market, By End-User

Hospitals Research Institute OthersGlobal Stem Cell Reconstructive Market, By Regions

North America Europe Asia-Pacific South America Middle East and Africa (MEA)Key Players operating the Global Stem Cell Reconstructive Market

Osiris Therapeutics NuVasives Cytori Therapeutics Takeda (TiGenix) Cynata Celyad Medi-post Anterogen Molmed Baxter Eleveflow Mesoblast Ltd. Micronit Microfluidics TAKARA BIO INC. Tigenix Capricor Therapeutics Astellas Pharma US, Inc. Pfizer Inc. STEMCELL Technologies Inc.

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Global Stem Cell Reconstructive Market- Industry Analysis and Forecast (2020-2027) - Unica News

Global Opthalmic Therapeutics Market reports offers vital insights that facilitate the trade consultants, product managers, CEOs and business executives to draft their policies on varied parameters together with enlargement, acquisition and new product launch in addition as analyzing and understanding the market trends.

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Regional Forecast of Opthalmic Therapeutics Market Emerging Technology (Analysis of COVID-19), Regional Imapact, Business and Industry Growth...

Fact.MR has introduced a new research report on the Opthalmic Drugs market. This report intends to offer a complete analysis of all the important factors and trends contributing to the growth of this market. Thus, the study offered in this report provides an assessment of vital restraints, drivers, opportunities, and challenges faced by players in the market for Opthalmic Drugs. In addition to this, it depicts a clear picture of demand opportunities in different regions of the Opthalmic Drugs market Trends during the tenure of 2020 to 2025. The Opthalmic Drugs market is estimated to show an upward graph of revenues together with an exceptional CAGR of around 4.2% during the tenure of 2020 to 2025. Thus, the market is all set to reach a value of around US$ xx Mn/Bn by 2025 end.

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Key product type explained in the Opthalmic Drugs market report are:

The list of important players profiled in the Opthalmic Drugs market report includes:

Based on geographical regions, the Opthalmic Drugs market is segmented as follows:

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Computer glasses are marketed to kids who use screens & now that more kids are doing virtual schooling, do we need expensive blue light lenses?

There is no overlooking that since we have been home due to the coronavirus pandemic in March that kids' screen time has skyrocketed. And really, how could it not? Even if you were able to be super strict about limiting their time on devices throughout the summer, now that we are back to school and a lot of people virtual learning, kids are back behind the computer quite a bit. This has us thinking a lot about our children's eye and really how healthy it is to be having that much screen time.

Because of this, something called "computer glasses" orblue-light-blocking glasses are starting to gain some popularity. According to PopSugar, their claim is to help "to combat the apparent shorter, blue-light wavelengths that are emitted from digital screens."

But are they really necessary?

As parents, we worry so much about our kid's eyes being behind the computer all day during virtual learning. We know how we feel starring at the computer screens all day for work and want to make sure that they are protected from anything harmful.

Dr. Scott Edmonds, an optometrist,shared withPOPSUGAR that kids eyes are"still-developing eyes generally allow for more high-energy blue light to reach and potentially damage their retinas" and that excessive blue-light emissions "may produce oxidative and phytotoxic damage to cells in the cornea and retina of the eye."

Digging deeper though, a recent study done by theInternational Review of Ophthalmic Opticsshows that there is a lack of"strong evidence" whenever it comes to the connection between eye strain and blue light.

RELATED:Students' Reaction To Teacher Disappearing From Video Meeting Is Priceless

Here's the thing though: the purpose of blue light, especially in relation to screens, is to keep people alert. However, it doesn't always come from screens. Nope. It's actually everywhere and can be found influorescent lighting, LED, but mostly - it comes from the sun.

Yup. And theAmerican Academy of Ophthalmology (AAO) even says that we get10 times as much blue light from the sun than we do from a computer screen.

"There's no scientific evidence to suggest that blue light from our screens or devices are damaging our eyes or our children's eyes," Dr. Purnima Patel, the clinical spokesperson for the AAO, said in a statement. "That's why the American Academy of Opthalmology does not recommend blue-light-blocking computer glasses."

So back to our original point about these expensive glasses that moms are fretting over purchasing: don't waste your money.

READ MORE:Teacher Shares Hack That Uses CDs To Solve Virtual Learning Tech Trouble

Sources: PopSugar, International Review of Ophthalmic Optics

Why Is A Pap Smear Test Important To Have Every Year?

Allison Cooper is a full-time blogger at Project Motherhood and freelance writer. Her writing can be found at Reader's Digest, Classpass, Romper, Working Mother, Mommy Nearest Magazine and more. When not creating content, she's spending time with her family, running, or sipping on strong coffee!

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Computer Glasses For Kids Don't Need To Be Expensive | Moms.com - Moms

Medical equipment manufacturer Wipro GE Healthcare has partnered with the Indian Institute of Science (IISc) to open a research lab.

The lab is located at the Department of Computational and Data Sciences (CDS) in Bangalore. It will specialise in healthcare diagnostics, deep learning technology, ML and AI systems. Work will also be done on digital interfaces to produce sophisticated diagnostic and medical image reconstruction techniques.

This research unit will involve around fifty students and three faculty members of IISc to begin with. They will work closely with clinicians as well as Wipro GE Healthcare to integrate computational models into clinical workflows, to help doctors improve patient outcomes.

The partners are aiming for this collaboration between the worlds of industry and academia to solve some of the toughest challenges healthcare faces, using artificial intelligence and machine learning. One of their work streams will be exploring deep learning models to analyse lung lesions caused by COVID-19 via ultrasound and CT images.

Additionally they will apply deep learning models to improve opthalmology imaging, and medical image reconstruction methods.

The IISc was established in 1909 through a partnership between founder of the Tata group Jamsetji Nusserwanji Tata, the Maharaja of Mysore, and the Government of India. Over the 111 years since its establishment, IISc has become a major institution for advanced scientific and technological research and education in India.

Wipro GE Healthcare is supporting the research lab with a grant as part of its CSR efforts. This funding will be used to equip the lab with the necessary hardware and software. This includes state-of-the-art deep learning servers and an advanced visualization platform.

Commenting on the collaboration, Dileep Mangsuli, Chief Technology Officer at GE Healthcare South Asia said: The world's healthcare is transforming through use of digital technologies which can enable precision health. This transformation can be accelerated by building a collaborative ecosystem of industry and academia partners.

"This Healthcare Innovation Lab at IISc will help bring to market unique digital solutions which will get integrated into our Edison platform and intelligent devices, helping clinicians solve some of the toughest healthcare challenges.

Prof. Phaneendra Yalavarthy, convener of the lab as well as the Chair of the Office of Development and Alumni Affairs at IISc, said: Private-Public partnership is in the DNA of IISc and this collaborative lab in the space of artificial intelligence in healthcare funded by Wipro GE Healthcare is timely, given the push for digital technologies.

"Translation of the research work carried out in the lab into the clinic will be the priority, and there is no better industry partner in India than Wipro GE Healthcare that can accelerate this. This is only the beginning of the collaboration and we are hoping to scale up the research activities in the near future.

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Research lab opens in India focused on deep learning | Technology & AI - Healthcare Global - Healthcare News, Magazine and Website

Latest launched research document on Ambulatory Healthcare IT Market (Covid-19 Version) study of 350 Pages provides detailed analysis with presentable graphs, charts and tables. The report also enlists several important factors share, size, growth, trends, global statistics, key manufacturers and 2027 forecast analysis. This report presents an in-depth assessment of the Ambulatory Healthcare IT including enabling technologies, Hey trends, market drivers, challenges, standardization, regulatory landscape, deployment models, operator case studies, opportunities, future roadmap, value chain, ecosystem player profiles and strategies. The Research Study also presents a complete assessment of the Market and highlights future trend, growth factors & drivers, leaders opinions, facts, and primary validated market data. This Ambulatory Healthcare IT market report provides detailed profiles of the key players to bring out a clear view of the competitive landscape of the Healthcare industry outlook.

Download Sample (350 Pages PDF) Report: To Know the Impact of COVID-19 on this[emailprotected]https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-ambulatory-healthcare-market&ab

Ambulatory Healthcare IT Market Scenario

According to Data Bridge Market Research the market for ambulatory healthcare IT is developing owing to certain parameters, such as administration commissions and maintenance for healthcare information and technology solutions, enhancing the application of big data mechanism, necessitate diminishing escalating healthcare expenses and tremendous profits on financing for healthcare IT solutions will help the market to grow. Some of the factors may hinder the business growth during the foreseen period such as information technology infrastructural restrictions in emerging nations and security concerns.

Market Drivers

Growing incidence of chronic diseases, is driving the market growth

Continuous technological advancement, is flourishing the market growth

Rising geriatric population, is helping the market to grow

Rising demand for minimally invasive surgeries, drives the market growth

Market Restraints

Inadequate communication, hinders the market growth

Prevalence of adverse drug activities, hampers the market growth

Delayed diagnostic, acts as a market restraints

The Ambulatory Healthcare IT Market Report provides in detail information about market analysis, market definition, market segmentation, key development areas, competitive analysis and research methodology. This Report Provides superior market perspective in terms of product trends, marketing strategy, future products, new geographical markets, future events, sales strategies, customer actions or behaviors. This market research study presents actionable market insights with which sustainable and money-spinning business strategies can be created. All this information, facts, and statistics lead to an actionable ideas, improved decision-making and better deciding business strategies. This Ambulatory Healthcare IT market research report is framed with the most excellent and sophisticated tools of collecting, recording, estimating and analysing market data.

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The Segments and Sub-Section of Ambulatory Healthcare IT Market are shown below:

By Type (Ambulatory Services, Primary Care Offices, Outpatient Departments, Emergency Departments, Surgical Specialty, Medical Specialty, Others)

By Modality (Hospital-affiliated, Freestanding), Surgery Type (Opthalmology, Orthopedics, Gastroenterology, Pain Management, Others)

By Application (Laceration Treatment, Bone Fracture Treatment, Emergency Care Service, Trauma Treatment)

Some of Key Competitors or Companies Included In the Study Are

AmSurg CorpSurgical Care AffiliatesSurgery PartnersHealthway Medical GroupSurgCenterTrillium Health PartnersMedical Facilities CorporationNueterra CapitalAspen HealthcareSuomen Terveystalo OyIntegraMed America, Inc.SHERIDAN HEALTHCARENueHealthAthenahealthGENERAL ELECTRICOptum, Inc.Apria Healthcare Group, Inc.DaVita Inc.LVL MedicalFresenius Kabi AGSonic HealthcareComplete Report is Available (Including Full TOC, List of Tables & Figures, Graphs, and Chart) @https://www.databridgemarketresearch.com/toc/?dbmr=global-ambulatory-healthcare-market&ab

This Ambulatory Healthcare IT Market Research document takes into consideration several industry verticals such as company profile, contact details of manufacturer, product specifications, geographical scope, production value, market structures, recent developments, revenue analysis, market shares and possible sales volume of the company. It consists of most-detailed market segmentation, systematic analysis of major market players, trends in consumer and supply chain dynamics, and insights about new geographical markets. The market insights and analysis provided in this market research document are based upon SWOT analysis on which businesses can trust confidently. This Ambulatory Healthcare IT report is produced by chewing over several fragments of the present and upcoming market scenario.

To comprehend Ambulatory Healthcare IT Market dynamics in the world mainly, the worldwide Ambulatory Healthcare IT market is analyzed across major global regions.

North America: United States, Canada, and Mexico.

South & Central America: Argentina, Chile, and Brazil.

Middle East & Africa: Saudi Arabia, UAE, Turkey, Egypt and South Africa.

Europe: UK, France, Italy, Germany, Spain, and Russia.

Asia-Pacific: India, China, Japan, South Korea, Indonesia, Singapore, and Australia.

This Ambulatory Healthcare IT Market Research/analysis Report Contains Answers to your following Questions

Which Manufacturing Technology is used for Ambulatory Healthcare IT?

What Developments Are Going On in That Technology?

Which Trends Are Causing These Developments?

Who Are the Global Key Players in This Ambulatory Healthcare IT Market?

What are Their Company Profile, Their Product Information, and Contact Information?

What Was Global Market Status of Ambulatory Healthcare IT Market?

What Was Capacity, Production Value, Cost and PROFIT of Ambulatory Healthcare IT Market?

What Is Current Market Status of Ambulatory Healthcare IT Industry?

Whats Market Competition in This Industry, Both Company, and Country Wise?

Whats Market Analysis of Ambulatory Healthcare IT Market by Taking Applications and Types in Consideration?

What Are Projections of Global Ambulatory Healthcare IT Industry Considering Capacity, Production and Production Value?

What Will Be the Estimation of Cost and Profit?

What Will Be Market Share, Supply and Consumption?

What about Import and Export?

What Is Ambulatory Healthcare IT Market Chain Analysis by Upstream Raw Materials and Downstream Industry?

What Is Economic Impact On Ambulatory Healthcare IT Industry?

What are Global Macroeconomic Environment Analysis Results?

What Are Global Macroeconomic Environment Development Trends?

What Are Market Dynamics of Ambulatory Healthcare IT Market?

What Are Challenges and Opportunities?

What Should Be Entry Strategies, Countermeasures to Economic Impact, and Marketing Channels for Ambulatory Healthcare IT Industry?

For More Information In the Analysis of Reports Please Visit:https://www.databridgemarketresearch.com/inquire-before-buying/?dbmr=global-ambulatory-healthcare-market&AB

Table of Content:

Market Overview: The report begins with this section where product overview and highlights of product and application segments of the global Ambulatory Healthcare IT Market are provided. Highlights of the segmentation study include price, revenue, sales, sales growth rate, and market share by product.

Competition by Company: Here, the competition in the Worldwide Ambulatory Healthcare IT Market is analyzed, By price, revenue, sales, and market share by company, market rate, competitive situations Landscape, and latest trends, merger, expansion, acquisition, and market shares of top companies.

Company Profiles and Sales Data:As the name suggests, this section gives the sales data of key players of the global Ambulatory Healthcare IT Market as well as some useful information on their business. It talks about the gross margin, price, revenue, products, and their specifications, type, applications, competitors, manufacturing base, and the main business of key players operating in the global Ambulatory Healthcare IT Market.

Market Status and Outlook by Region:In this section, the report discusses about gross margin, sales, revenue, production, market share, CAGR, and market size by region. Here, the global Ambulatory Healthcare IT Market is deeply analyzed on the basis of regions and countries such as North America, Europe, China, India, Japan, and the MEA.

Application or End User:This section of the research study shows how different end-user/application segments contribute to the global Ambulatory Healthcare IT Market.

Market Forecast:Here, the report offers a complete forecast of the global Ambulatory Healthcare IT Market by product, application, and region. It also offers global sales and revenue forecast for all years of the forecast period.

Research Findings and Conclusion:This is one of the last sections of the report where the findings of the analysts and the conclusion of the research study are provided.

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The orphan drug market is continuously growing over the years now at twice the growth rate of overall prescription drug market due to the arising interest from pharmaceutical companies for underlying benefits and involvement of many smaller biotechnology start-up companies who are primarily focused on rare diseases. However still there are lot of attention that needs to be given since the ratio of one having rare disease is 1 in 2000 leading to the lack of knowledge about disease mechanisms, along with FDA/Marketing approvals which take years.

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Ambulatory Healthcare IT Market By Business Growth, Trend, Segmentation, Top Key Players, Revenue and Industry Expansion Forecast Report|mSurg Corp,...

Santa Clara, CAMore Elmiron lawsuits are being filed in the U.S. and Canada has filed two class action lawsuits, all alleging the interstitial cystitis drug can cause permanent vision damage.

While plaintiffs complaints differ regarding how long Elmiron was used to treat interstitial cystitis, and a range of vision problems have been cited, all lawsuits, including the class action in British Columbia and the other in Quebec, are similar. All claim the manufacturers failed to disclose the serious link between Elmiron use and significant visual damage, including pigmentary maculopathy and Elmiron did not properly warn patients of the risks, according to the Quebec complaint.

In August 2020, two women in the U.S. filed lawsuits against Elmiron manufacturers Johnson & Johnson and its subsidiary Janssen, Bayer and Tevaaccusing them of failure to warn consumers of Elmirons risk, negligence, designing Elmiron in a way that makes the drug defective and hazardous to health, and fraudulent misrepresentation of the risks associated with Elmiron. One woman had taken Elmiron for about four years, the other woman ten years. These complaints (cases are Johns v. Alza Corp. et al., case number 3:20-cv-10341, and Levy v. Alza Corp., case number 3:20-cv-10342, both in the U.S. District Court for the District of New Jersey).

The British Columbia plaintiff, Arenlea Felker, filed the Elmiron side effects class action lawsuit against Janssen Inc. and Teva Branded Pharmaceutical Products R&D Inc. Felker, prescribed Elmiron to treat interstitial cystitis in 2005 and continued to take the medication daily, allegesthat the drug caused permanent vision-threatening eye disease called pigmentary maculopathy.

In a study published in Opthalmology back in November 2018, researchers concluded that maculopathy associated with chronic exposure to PPS is possibly avoidable". Another study published in January 2019 associated the Chronic use of pentosan polysulfate sodium with risk of vision-threatening disease, and a number of articles have been published with similar conclusions.

As well, studies have found that patients with interstitial cystitis who don't use Elmiron have no instances of pigmentary maculopathy. But many other issues are related to vision loss, from mental health issues to a higher risk of falling. One 2014 studypublished in JAMA Ophthalmologylinked poor vision to a reduced life expectancy. Additional issues can include cognitive decline, difficulty learning, and a feeling of being discriminated against.

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More Elmiron Lawsuits, including Canada Class Actions, and the Impact of Vision Loss - LawyersandSettlements.com

28 September 2020

Gilson Gray

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Because women typically live longer than men and may have asmaller pension pot, they need to plan accordingly to make theirmoney last.

While longevity sounds like a blessing, we wouldn't want tobe unwell and struggling financially during our later-life years.But many women run the risk that this will be their future. Notbecause they've got the 'right genes' or live asuper-healthy lifestyle: it's simply because they were born awoman.

A 40-year-old woman has a one in four chance of living to age96, and a one in ten chance of living to 100.1 Betterhealthcare and positive lifestyle changes have helped to raise lifeexpectancies across the board, but women still are likely to livelonger than men. And with several studies finding that more menthan women have died from COVID-19, the life expectancy gap couldwiden further from here.

Women not only need their pensions to last longer, they alsogenerally have smaller pension pots to use during these extra yearsof life. We already know that women typically retire with one-fifthof the pension wealth of men.2 New analysis from theCentre for Economics and Business Research found that, when lifeexpectancy is taken into account, the gender pensions gap could beas much as 108,130 for single women, and 186,120 forwomen who are married or in a relationship.3

Because they tend to live longer, women are more likely to endup in single-person households later in life. This could addfurther to their financial pressures because it can be much moreexpensive to run a household of one, covering all bills alone.

Adding to this, the State Pension age is rising, which meansmany people who will rely on this government payment will have towork longer before they can claim it. Plus, there's noguarantee your health will support you working into your lateryears.

Some women may have taken their first job at 16. If you'replanning on working until your late 60s or early 70s, that's alot of years in the workforce - you might well be feeling burnt outor struggling with health issues. As early as your mid-40s or early50s, you could be suffering from symptoms of the menopause, such as'brain fog', which can make it tough for some women tocontinue working at the pace they once did.

You may want to drop to part-time hours or get a job with lessresponsibility to take some of the pressure off, even if it justfor a few years. But will you be able to afford it?

For women in same-sex relationships, they may think that theirjoint longevity will give them a long and happy retirementtogether. But in fact they could face a triple whammy ofchallenges: both partners might take a period of maternity leavethat could impact their earning power and pension contributions,both may need to work longer, and both may suffer from healthconditions over their long lives.

Luckily, there are things all women can do to increase yourchances of a financially secure life, however long you live. If youdo nothing else, have a think about what you want your future tolook like. Do an appraisal of all your long-term savings plans,rounding up any small savings pots you may have forgotten aboutover time. Sit down and have a chat with a financial adviser to seehow things are actually looking for your retirement years. Takinginto account the money you've already saved, and your capacityto save over the coming years, an adviser can model a likelyoutcome.

You may find that you can retire sooner than you think or canslow down your working pace as you near retirement if you come upwith a sensible plan now. Take charge today and speak to your St.James's Place Partner for help with your finances.

Footnotes

1. ONS life expectancy calculator, accessed 7 September2020

2. Securing the Financial Future of the Next Generation,Insuring Women's Futures and Chartered Insurance Institute,2018

3. Centre for Economics and Business Research, September2020

The content of this article is intended to provide a generalguide to the subject matter. Specialist advice should be soughtabout your specific circumstances.

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Mayer Brown

The topic of employers looking to change employment contract terms is becoming increasingly important as we move towards the end of the Coronavirus Job Retention Scheme (CJRS) and beyond.

Mayer Brown

In our latest episode Nick looks at a case where the employee tried to rely on the GDPR and Human Rights to prevent disciplinary proceedings being taken against her.

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Women's Health, Wealth And Longevity - A Retirement Triple-Threat - Employment and HR - UK - Mondaq News Alerts

Among Us and Fall Guys have been in a tussle to see who can capture more fans. As of now, Among Us seems to be the clear winner with the popularity of the game still rising. On the other hand, Fall Guys is seeing a steep, downward trend which is quite alarming for the game.

Regardless of its popularity, Among Us shouldnt be too quick to celebrate. The gaming industry is constantly innovating and really dynamic. Just like it rendered Fall Guys pretty irrelevant, there might soon come a game that would do the same to Among Us.

However, analyst Rod Breslau feels that there is one solution that would help both the games stay relevant for a long time. The idea would increase engagement among players.

Many games such as GTA 5 and Minecraft have involved the community in their development process. It is safe to say that a majority of them have seen rising engagement in players as well as a jump in sales. The freedom to include an element of ones creativity in the game always motivates fans. There is similar scope for both the games in question concerning their maps.

Popular streamer Shroud has already urged Fall Guys to add maps, especially if the game wants to stay in the race. It would make it so much easier for the developers to give that responsibility to the community.

This would allow the community to flaunt its creative side. Allowing players to make community maps will provide unlimited and constant new content for the game.

With limited maps and modes, the game becomes a bit repetitive after a while. This wont happen if they have unlimited access to new maps and tasks.

Not only is this Slashers opinion but that of many fans as well. They think that this something the developers should have included since the inception of the game.

While Among Us has other plans for the game to keep it interesting, Fall Guys needs to work on this stat!

It might not be that easy a task because it would require major changes in the game. Therefore, no matter how much criticism the game faces, it will still be a while until we are able to see those options come to the game. Till then, just like Among Us, Fall Guys too can work on other strategies to stay featured in the spotlight.

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Among Us and Fall Guys Can Ensure Longevity With This Feature - Essentially Sports

DANVERS, Mass.--(BUSINESS WIRE)--Health care costs are a major expense during the Womens Longevity Gap, the period in which a woman will need to cover expenses single-handedly after the death of a male spouse or partner, according to recent data from HealthView Services, the nations leading provider of health care cost projection software. The company estimates that in retirement an average, healthy 43-year-old woman will face nearly $200,000 more in health insurance premiums than her husband.

The company, which provides software for personalized health care cost projections to financial professionals, urges women and couples to start planning early to address the longevity gap.

HealthView Services encourages thoughtful, personalized planning for the disparities of age, income, and life expectancy that commonly exist among male/female couples. Recommendations include:

Following these steps, women and their financial advisors can mitigate and potentially even eliminate the longevity gap and the other challenges that are common among female retirees, said Ron Mastrogiovanni, CEO of HealthView Services. Financial advisors with the right tools and data at their fingertips have the power to help their female clients close that longevity gap.

About HealthView ServicesFounded in 2008, HealthView Services is the nations leading provider of healthcare cost projection software, built on a dataset of 530 million health care claims. Its portfolio of retirement healthcare planning applications centered on personalized longevity estimates and individual health care cost projections is used by advisors, financial institutions, employers and consumers to create comprehensive, reliable health cost projections for 33 million users annually. Visit us to know more: http://www.hvsfinancial.com.

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Women's Health Care Costs in Retirement Projected to be $200000 More than Men's - Business Wire

At 69.4 years, Indias life expectancy has made almost a 20 year leap from 49.7 in 1970-75. While this is no mean feat, the sobering reality is that Japan was here in 1960 and China in 1990. The link between poverty and life expectancy is fairly obvious looking at the India story. People in Delhi, Kerala, Jammu & Kashmir, Himachal Pradesh, Punjab, Maharashtra and Tamil Nadu with lower incidence of extreme poverty live longer than the national average. Poorer states like Chhattisgarh, UP, MP, Assam, Rajasthan, Bihar and Jharkhand drag down life expectancy.

Worries that Indias current economic difficulties are turning the clock back in the fight against poverty make life expectancy a key indicator to track. Countries like Nepal and Bangladesh had lower life expectancy than India in the 1980s, but they have now pulled ahead. Apart from the incidence of poverty, access to public health services could be an equally important factor separating Indian states. This is borne out by infant mortality and maternal mortality rates largely correlating with life expectancy. Keralas IMR is 7 per 1,000 live births, Delhis 13 and TNs 15 against 48 in MP, 43 in UP and 41 in Assam.

The Covid pandemic may be a short term phenomenon. But its effect on lives and health services has multiple dimensions with generational implications. State outreach like immunisation and supplemental nutrition schemes took a backseat this year. Treatments became harder to access, evident in statistics of fewer surgeries, procedures and OPD visits for heart diseases, cancer, TB etc. The loss of incomes and livelihoods will force many to scrimp on meals and protein-rich foods. A vigorous public health response to neutralise these setbacks is needed.

Total fertility rates have fallen sharply below replacement levels in most Indian states, barring a few like UP and Bihar. Coupled with better institutional services and families investing in fewer children, this could help reduce malnutrition and IMR. While the Centre is betting big on health insurance for the poor, this cannot substitute adequate doctor availability and healthcare infrastructure in rural areas. The neglect of public healthcare by successive governments has been extremely expensive for the country. While this must be urgently remedied, only a growing economy will enable the government to make these interventions and citizens to live longer and healthier lives.

This piece appeared as an editorial opinion in the print edition of The Times of India.

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Longevity gap: Poverty remains a scourge. India must focus on economy, public health - The Times of India Blog

Its not hard to see why yoga has become so popular. In addition to helping with strength, balance, and body awareness, its meditative qualities can help center your life and reduce stress and anxiety. Taking a yoga class with a professional yoga instructor is an absolute must since some moves can be dangerous if not performed properly.

Taking yoga as a group class, additionally, will allow for the meditative qualities of yoga to be enhanced by group participation and will give you the motivation to participate more fully in the spiritual aspects of the practice. Being a group yoga classalso allows you to benefit from the shared, collective energy of the group, and youll be able to leverage that energy throughout your yogic flows. For those who struggle to stay consistent with their yoga effortsparticularly beginnersthese classes can be a great way to create accountability, learn from others, and make it more fun.

Taking a group dance class can be an incredibly fun social experience, especially if you go with your significant other. Dance has many of the same advantages of yoga, including strength, balance, and cardio training, but instead of meditation, it concentrates on interpersonal interaction.

The social aspects of group dance go back to ancient traditions. All over the world, dance would have incredible importance in the ritual life of the community. Many of these ancient rituals have been lost, but some of those social benefits can be tapped into. Be it through swing, salsa, and other group dance classes. In fact, the ability to build close connections with your fellow dancers is one of the biggest benefits.

Because dancing involves physical connection, it allows you to bridge the gap between human interaction and human touch. Group dance classes are also almost always more affordable than private lessons, and youll benefit from getting a firsthand look at how many different people have different styles and approacheseven for the same dance.

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Top 5 Group Exercise Classes for Your Return to the Gym - Longevity LIVE

Its a diet thats really effective in weight loss and is a good diet for those that are currently severelyobese. Thererealso cases of the diet being really effective in dealing with type two diabetes, as many followersof this diet have been able to put the disease in remission, however, more evidence is needed on this front to determine its viability in combating diabetes.

The way the diet works is pretty simple. By drastically reducing carbohydrates and replacing themwith fat, yourbody is put in a metabolic state called ketosis.Being in this state makes your body really good at burning fat for energy, and this type of diet is also great at reducing blood sugar and insulin levels.

There are various forms of the Ketogenic diet. However, they all follow the main basic principle: fewer carbs and more fat. There is the Standard ketogenic diet, which can be broken down as 75% fat, 20% protein, and 5% carbs; High-protein ketogenic diet, which has a 15% increase in protein and a corresponding decrease in fat consumption; Cyclical ketogenic diet, which allows you to have two days a week of eating more carbs; and Targeted ketogenic diet, that allows you to add carbs around a workout.

When on a Ketogenic diet, there is only a certain amount of food you are permitted to eat. This includes meat, particularly red meat, and pork, as well as fatty varieties of fish like salmon, tuna, and mackerel. Eggs are good to have, as well as cheese like cheddar and mozzarella. Avocados are also very worthwhile food to eat on this diet, as there are lots of health benefits when it comes to consumingavocados.

It may sound strange, due to other diets encouragement of high fruit and vegetable consumption, but for the Keto diet, its critical that you avoid all fruit and root vegetables such as potatoes, carrots, and parsnips. Sugary food is also a no-go, as sugar is just a form of carbohydrates, which also means you should avoid wheat-based products like pasta. Its also important that you avoid alcohol, as due to its carb content you would turn the ketosis process off.

There are negatives tothis diet, however, and the main one is that for it to work, it needs to be followed strictly. If not, your body will fail to entera ketogenic state, meaning that youll actually store the fats youre eating, making you put on weight. It can also make you feel extremely tired and fatigued when you first start the diet, and could also see you get an increase of headaches and muscular pain.

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Finding The Right Diet To Eat For You and Your Body - Longevity LIVE - Longevity LIVE

Dry shampoos are taking the beauty world by storm. You can freshen up your hair quickly, although many products leave a white residue on your hair. Not with COLABs award-winning products, which is why we think you would love this review.

Unlike standard shampoos, dry shampoos require absolutely no water so its the perfect choice to freshen up hair quickly and on the go! Just spray, massage and style!

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You Will Love This Dry Shampoo With No White Residue - Longevity LIVE - Longevity LIVE

I am writing in response to the Steamboat Pilot & Today article titled, The Longevity Project, Part 4 | Plants over pills: Non-traditional medicine growing in popularity, especially in Colorados mountain towns.

I first started my career in the medical realm as an occupational therapist and changed careers after my masters degree in social work.I have worked in the medical field in Steamboat Springs and currently own the integrated holistic clinic Minds in Motion.

I have been on both the conventional medicine side and also the holistic side with two different careers and love and respect both approaches.Anyone who knows me or what I have tried to give to this community for 18 years knows that I advocate strongly for the partnership of western/conventional medicine and holistic medicine.We must work together to give best practice of care and break the stigma of a right medicine.

I am responding to the article printed last week, because I believe the article was well intended but lacking in objectivity and information.Strained relationships and degrading comments about each side of medicine may be a little outdated, as there have been strong relationships between the two sides for over two decades, with many university hospitals now having alternative branches of care under their same roofs.

In our community of Steamboat, Minds in Motion works closely with physicians from all specialties including but not limited to pediatrics, orthopedics, family medicine, workers comp and internal medicine.Minds in Motion practitioners strongly recommend clients using their primary care physicians as part of their care plan.

Alternative medicine is a large category, and one must be careful when considering alternative medicine. The National Center for Complementary and Alternative Medicine is a branch of the National Institute of Health and has compiled thousands of peer-reviewed, evidence-based studies on effective alternative practices such as meditation, acupuncture, yoga and functional medicine.This medicine is put through the same rigorous reviews as western and conventional medicine and is often times hundreds, if not thousands, of years older than western and traditional medicine.If a client is looking for care, they should review the efficacy of every treatment regardless of what category it falls under.

Another aspect to consider when looking at your medical provider is level of education and where and how that provider is licensed for accountability of care.Sometimes, accountability is late in the game even on the conventional medicine side. For example, my degree of occupational therapy, which is currently a masters level of education, was only licensed in Colorado in 2008.Psychotherapists dont even need a masters degree to practice in the state of Colorado but can register through the state licensure anyway (ask your counselor for a disclosure of their education to cover this loophole).

At Minds in Motion, all alternative and holistic providers have a masters degree or higher of education from an accredited university and are licensed by a governing body. Dr. Fegley is an MD with additional certifications in functional medicine, and Dr. Grace Charles is an ND with similar educational demands as conventional medical school. It is for this reason we dont need to put quotation marks around doctor.

It only takes a couple minutes to do your homework to make sure your provider isnt a huckster. You can search for any licensed provider in the Colorado Department of Regulatory Agencies website athttps://dora.colorado.gov/.Some alternative medicine providers are still amazing even if they arent regulated by a governing body and can address the mind/body/spirit connection in a way that our culture doesnt value. Please remember that, but know your provider and ask the questions about their education or skills.

Angela Melzer, LCSW, OTR/LMinds in Motion owner

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Letter: We need to break the stigma of the 'right' medicine - Steamboat Pilot and Today

Even more encouragingly, evidence suggests that increasing our heart rate through exercise changes our brain chemistry, increasing anti-anxiety neurochemicals such as mood-enhancing serotonin.

If you dont usually make exercise a planned part of your day, it may be difficult at first to get the ball rolling, but the trick is to start small. You do not have to buy expensive equipment or join a high charging gym, simply schedule a time (perhaps on your lunch break, or when you get home from work) to go for a 30-minute walk. Once youve done this for a month, youll know youve cemented the idea of exercise time into your routine, and can be a little more ambitious perhaps booking a yoga class, or heading to the local swimming pool.

Whatever it is, by creating the time to be physically active every day even if its just engaging in a bit of enthusiastic housework or gardening you can enjoy all those mood-boosting brain chemicals and become that bit more mindful, learning to live in the moment with a bit more ease.

Research into the human microbiome (the vast collection of bacteria and fungi that live within our bodies, and most particularly in our gut) suggests that our digestive health has a surprising link to our mental health and that making certain food choices can help our mood. While a healthy diet looks different for everyone, some good tips are:

5. Actively practice gratitude and acceptance

Whether its a difficult divorce, impending redundancy, or a devastating pandemic, there are some events in life which cannot be solved in a way which we find constructive and satisfying, no matter how hard we try. And while everyone finds these situations hard to cope with, they can be doubly challenging for those who also live with anxiety. Sometimes we need to focus on simply getting to the other side of a rough patch rather than thriving, but we can make this easier by embedding habits into our life which increases our resilience and coping skills.

Within a daily journaling habit, we can acknowledge the things that are out of our control. We can also still explore productive strategies to mitigate their impact through the actions we can control. For example, if you are going through a breakup, you may not be able to control how your ex-partner feels and reacts, but you can use calming techniques like breathing exercises to respond to the situation in a way that you will later feel proud of.

A big part of this is a daily practice of acceptance and gratitude. The prayer from theologian Reinhold Niebuhr, Grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference may be oft-repeated, but its message rings true.

If we can learn through daily reinforcement to accept what we cannot change and to notice the things which we are grateful for (even if, on some bad days, its nothing but appreciating the small beauty of sunlight falling through a window) we can find anxiety in challenging situations easier to cope with.

Excerpt from:
Seven Daily Habits To Reduce Anxiety - Longevity LIVE - Longevity LIVE

Okinawa has the highest concentration of centenarians in the world, and the regional diet and lifestyle may be the key to Okinawans remarkable longevity.

Okinawa is the largest of the Ryukyu islands, which sit southwest of Japan between the East China and Phillippine Seas and near to Taiwan. The traditional Okinawa diet is high in carbohydrates, low in calories, and emphasizes locally grown plants and vegetables.

Overall, the diet is filled with nutrient-dense but low-calorie foods, resulting in a slight calorie deficit. Healthcare organizations such as the NHS recommend between 2000 and 2500 calories per day. While the typical, traditional Okinawa diet yielded approximately 11 percent less than the RDA. Several studies indicate that a minor caloric deficit may lead to improved overall health when combined with sufficient nutrients.

According to a report by Science Direct, Okinawa has 68 centenarians for every 100,000 residents. This is more than three times the number of centenarians found in comparable U.S. populations. More than 85 percent of the people who reach 100 years of age are women.

The Okinawa Centenarian Study (OCS), founded in 1975, has been investigating the life expectancy of Okinawa citizens over 100 for more than 45 years. By 2016, the OCS had examined 1,000 centenarians from the Okinawa region.

Okinawans have a high life expectancy, and many people also enjoy extremely good health well into their old age. Approximately two-thirds of Okinawas centenarians live independently until the age of 97. The islands oldest inhabitants also show little sign of cardiovascular disease. They also experience far lower rates of cancer, diabetes, and dementia than other comparably aging populations.

So what exactly does the Okinawa diet include? And why is it so healthy?

In the mid-20th centurywhen Okinawas current centenarians were young adultsthe typical island diet focused on home-grown vegetables, tofu, and small quantities of seafood. Approximately 60 percent of total calories came from a local, purple-fleshed variety of the sweet potato known as beni imo, as well as the white-fleshed tuber taro.

Beni imo, in particular, is an Okinawan staple. Restaurants, stores, and street food stalls all stock the bright purple potato. In Japan, there is even a beni imo flavored KitKat. In its natural form, it is extremely high in B vitamins and potassium and contains a higher concentration of the antioxidant anthocyanin than blueberries. Beni imo is also high in vitamin C, vitamin A, and has a low glycemic index that can help regulate blood sugar.

Overall, the Okinawa diet of the mid-20th century features what is now known as the Okinawan ratio of 10:1 carbohydrate to protein. While not technically a low protein diet, it still particularly emphasizes carbs. It also deprioritizes animal-derived proteins such as seafood and red meat.

By as early as the late 19th century many Okinawan households kept a family pig. But pork products were and are mostly eaten in moderation or as celebratory foods. Meat and seafood make up just 2 percent of the traditional islander diet.

While informed by a variety of neighboring countries and cultures, Okinawan cuisine is singular. Many of the regions popular dishes are completely unique to the archipelago. Chanpur, a popular stir-fry, combines tofu with a small portion of vegetables, meat, or fish.

Variations may include gy, a bitter melon, along with thinly sliced pork or spam. While not meat-free, this dish notably emphasizes plant foods and vegetables as the heart of the meal.

Cabbage, okra, pumpkin, and daikon radish are also popular ingredients. These types of vegetables make up approximately 60 percent of the traditional Okinawan diet. Grains such as wheat, millet, and rice make up 33 percent. While soy-based foods such as tofu, miso, and edamame make up 5 percent.

Because of its location, the Pacific archipelago of Okinawa blends cuisine and cooking styles from China, Southeast Asia, and Japan. Both Okinawa and Japan have food-centered cultures, while the concept of food as medicine is commonplace in China.

The Okinawa diet incorporates this, particularly through its use of herbs and spices thought to have medicinal properties, such as turmeric. The vibrant yellow or orange spice contains curcumin, which some studies indicate has significant anti-inflammatory properties. It may also lower the risk of heart disease and Alzheimers.

While there are a variety of different factors that contribute to longevity, access to healthy food does significantlyand demonstrablyimpact health. According to the Physicians Committee for Responsible Medicine (PCRM), plant-based whole foods can prevent and treat many chronic health conditions, such as inflammation and diabetes.

The traditional Okinawa diet includes seaweed, particularly kombu and wakame. Both varieties are rich in vitamins and known to reduce blood cholesterol and hypertension. Wakami is also high in iodine, iron, and calcium, along with vitamins A and C. Much like the beni imo, wakame can help regulate and maintain blood sugar levels.

The modern Okinawa diet still emphasizes traditional foods, but westernization and other factors have led to an increase in the consumption of meat, processed food, and refined sugar. By the year 2000, the risk of heart disease and other health concerns had risen significantly.

While there is no magic wand for long life, research increasingly indicates that emphasizing plant-based foods, whole grains, and unsaturated fatsalong with an active, healthy lifestylecan support personal health and even longevity. Much like the diets found in any of the other so-called Blue Zones around the world.

Blue Zones are regions where the local population lives longer than the global average. National Geographic fellow, author, and explorer Dan Buettner first coined the term in 2004.

Specific Blue Zone regions include Icaria in Greece, Sardinia in Italy, the Nicoya Peninsula in Costa Rica, Loma Linda in California, and Okinawa. While diets in these regions naturally vary, there are a few common factors. Including a particular emphasis on carbohydrates and plant foods.

Beans and legumes are also widely thought to support longevity. As is limiting the consumption of red meat in favor of small quantities of fish or plant proteins. Not overeating, and consuming the bulk of the days calories in the morning and afternoon may also contribute to a longer life.

Plant foods are high in fiber, which significantly reduces the risk of cardiovascular disease and certain cancers. While the natural estrogens in tofu and other soy products, flax, legumes, and broccoli are thought to contribute to the longevity of Blue Zone and Okinawan women, in particular.

There are other cultural and social factors in longevity, too. In Okinawa, consistent and supportive social interaction may contribute to the islanders health. A moai is a lifelong circle of friends that supports each other into old age. This concept comes from the ancient practice of yuimaru, or mutual aid, which helped support community members with the greatest need.

Now, Okinawans form moai as supportive social groups, but members continue to support one another as much as possible. Loneliness has a significant impact on physical and mental health, and studies indicate that tight-knit communities and regular socializing can reduce depression in older people.

The Mediterranean and other Blue Zone regions also emphasize both socializing and staying active within the community. Exercise, regular time with others, and healthy eating intersect and provide overall health improvements.

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Is the Okinawa Diet the Secret to a Longer Life? - LIVEKINDLY