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If you are living with type 2 diabetes, you certainly are not alone. One in 10 people in the US has diabetes, according to the CDC. However, despite considerable progress in diabetes treatment over the past 20 years, fewer than half of those with diabetes actually reach their target blood sugar goal.

In part, this may be because doctors can be slow to make changes to a patients treatment plan, even when a patients treatment goals are not being met. One reason for this may be the overwhelming number of medications currently available. And yet, waiting too long to adjust treatment for type 2 diabetes can have long-lasting negative effects on the body that may raise the risk of heart and kidney disease and other complications.

Type 2 diabetes is a chronic disease where the bodys ability to use glucose or sugar as fuel is impaired. Our bodies produce a hormone called insulin which enables sugar from carbohydrates in food we eat to reach the cells and be used as energy. In type 2 diabetes, insulins ability to do its job is compromised, and over time the body actually produces less of it. This means less sugar in the cells for fuel, and more sugar in the blood where it cant be used. Having high levels of blood sugar over time can cause damage to vital organs like the heart, kidneys, nerves, and eyes.

Some risk factors that predispose people to developing type 2 diabetes, such as genetics and age, are not modifiable. Other risk factors, such as being overweight or having obesity, can be altered. This is why losing 5% to 10% of ones baseline weight by healthful eating and physical activity remains the backbone of type 2 diabetes management.

The blood sugar goal for most adults with diabetes is an A1C of below 7%. (A1C is a measure of a persons average blood sugar over a period of about three months.) In many people, diet and exercise are not enough to reach this goal, and one or more medications may be needed. Metformin is a tried and tested medicine that has been used for many decades to treat type 2 diabetes, and is recommended by most experts as first-line therapy. It is affordable, safe, effective, and well tolerated by most people.

When metformin does not adequately control blood sugar, another medication must be added. It is at this point that doctors and patients must choose among the many drugs and drugs classes available to treat type 2 diabetes. In general, for people who are at low risk of heart disease or have no history of diabetic kidney disease, most diabetes medications that are added to metformin effectively reduce blood sugars and can lower A1C to under 7%.

So, how to choose a medication? Each person with diabetes has their own goals, needs, and preferences. Before choosing a medicine, it is important to ask some relevant questions: Is my blood sugar at goal? Is this medicine affordable? Do I have heart or kidney disease? What are the side effects? Is it a pill or injection, and how often is it taken?

Regardless of which treatment is selected, the American Diabetes Association Standards of Care recommends reassessment of diabetes control every three to six months, followed by modifications to treatment if needed.

Lately, newer treatment options for type 2 diabetes glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter-2 (SGLT2) inhibitors have been heavily advertised. These newer drug classes lower blood sugar and also have cardiovascular and kidney benefits.

GLP-1 receptor agonists are drugs that lower blood sugar after eating by helping your bodys insulin work more efficiently. All drugs in this group except one are self-injected under the skin, either daily or weekly. Several of them, such as liraglutide (Victoza), semaglutide (Ozempic), and dulaglutide (Trulicity), have been shown to lower the risk of cardiovascular disease in people who are at high risk for it, or who have pre-existing heart disease. They also promote weight loss. Some people who take GLP-1 receptor agonists may have side effects such as nausea and vomiting, and in very rare cases pancreatitis.

SGLT2 inhibitors like empagliflozin (Jardiance), canagliflozin (Invokana), dapagliflozin (Farxiga), and ertugliflozin (Steglatro) are also a newer class of medications that work by blocking your kidneys from reabsorbing sugar back into your body. They also have cardiovascular benefits, especially in those who have heart failure, and have been shown to slow the progression of diabetic kidney disease. Other benefits include lowering blood pressure and promoting weight loss. Use of these medications may increase the risk of genital yeast infections, especially in women. A rare but serious consequence of SGLT2 inhibitors is diabetic ketoacidosis, which is a medical emergency that can be avoided by stopping these medications in consultation with your doctor before major surgeries, or if you are ill or fasting.

While these diabetes medications certainly have more to offer than just improvements in blood sugar, they remain costly and inaccessible to many individuals. This is why it is essential to have an open and honest conversation with your doctor about what is most important to you and what aligns with your goals and preferences. Management of a complex disease like diabetes takes an entire team, with you being the key team member.

Link:
Type 2 diabetes: Which medication is best for me? - Harvard Health Blog - Harvard Health

Bariatric surgery, or weight loss surgery, significantly reduced the risk for pancreatic cancer in patients with obesity and diabetes, according to study results presented at UEG Week Virtual 2020.

Obesity and diabetes are well-known risk factors for pancreatic cancer via chronic inflammation, excess hormones and growth factors released by body fat, said Dr. Aslam Syed, fellow of gastroenterology and hepatology at Allegheny Health Network in Pittsburgh, Pennsylvania and lead author of the study, said in a press release. Previously, bariatric surgery has been shown to improve high blood sugar levels in diabetic patients, and our research shows that this surgery is a viable way in reducing the risk of pancreatic cancer in this growing, at-risk group.

In this study, data from 1,435,350 patients with obesity and diabetes were assessed over a 20-year period. Of these patients, 10,620 (73% women) underwent bariatric surgery, during which the digestive system is changed to help patients lose weight.

Patients who underwent bariatric surgery were less likely to develop pancreatic cancer compared with those who did not undergo the surgery (0.32% vs. 0.19%).

Clinicians should consider bariatric surgery in patients with metabolic disorders such as diabetes and obesity to help reduce the risk and burden of pancreatic cancer, said Syed.

In the press release, Syed elaborated on the importance of pancreatic cancer prevention, especially since survival has not improved in this area for decades. The average survival time at diagnosis is particularly bleak for this silent killer, at just 4.6 months, with patients losing 98% of their healthy life expectancy, said Syed. Only 3% of patients survive more than five years.

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Weight Loss Surgery May Reduce Pancreatic Cancer Risk in Patients With Diabetes and Obesity - Curetoday.com

Compared with men and patients with HIV not receiving integrase strand transfer inhibitors (INSTIs), women are more susceptible to INSTI-associated weight gain, according to a study results presented at IDWeek, held virtually from October 21 to 25, 2020.

An emerging issue associated with INSTI antiretrovirals is excessive weight gain. There is also a known association between excess weight and impaired glucose tolerance; however, the metabolic implications of INSTI-associated weight gain have not been established. Therefore, in the current study, researchers evaluated the prevalence of INSTI-associated weight gain among a diverse, urban population, and investigated potential risk factors and metabolic implications.

Of the 612 patients included in the study, 123 were initiated with INSTIs and 489 with alternative anchor regimens (non-INSTIs). Patients with a diabetes mellitus (DM) prescription before antiretroviral therapy (ART) initiation were excluded. Researchers compared patients who were initiated with INSTIs with those with an alternative regimen who remained on their initial regimen for at least 18 months. In total, 237 patients (38.7%) were women, had an average age of 41.56 years, and an average body mass index (BMI) of 25.55 (range, 22.9-28.9); 339 patients (55.4%) were Black/African American.

The primary outcome of the study was percent weight change in the first 24 months of ART. The secondary outcome was incident DM diagnosis in the 19 months after ART using progression-free survival.

Results suggested that women were more susceptible to INSTI-associated weight gain. The INSTI vs non-INSTI cohort experienced a higher percent weight gain in the first 24 months post-ART initiation. Furthermore, women vs men in the INSTI cohort experienced a higher percent weight gain in the first 24 months (+9.57%; P =.002).

The adjusted multivariable analysis of 24-month weight gain due to INSTIs showed a weight gain of 1.68% (95% CI, -3.88% to 7.24%) in White men, 2.08% (-2.52% to 6.68%) in non-White men, 10.62% (2.83%-18.41%) in White women, and 11.02% (5.17-16.88) in non-White women.

Compared to non-INSTI regimens, the use of INSTIs was also associated with more incident DM diagnoses in the first 18 months of ART (hazard ratio, 3.27; P =.014).

Women having higher INSTI-associated weight gain suggests they may be more susceptible to adverse metabolic issues, the researchers concluded.

Disclosure: Several study authors declared affiliations with the pharmaceutical industry. Please see the original reference for a full list of authors disclosures.

Reference

Asundi A, Olson A, Jiang W, et al. Risk factors and metabolic implications of integrase inhibitor associated weight gain. Presented at: IDWeek 2020; October 21-25, 2020. Poster 946.

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Women Show Higher INSTI-Associated Weight Gain and Incident Diabetes Mellitus Than Men - Infectious Disease Advisor

Research suggests that women with polycystic ovary syndrome (PCOS) are more likely to develop type 2 diabetes mellitus. Lets try to understand how these two conditions are related. Also Read - That stubborn acne could be a sign of PCOS: Know how they are related

PCOS is a hormonal disorder that is common among women of reproductive age. It is a condition in which the ovaries produce an abnormal amount of androgens, also called male sex hormones. The hormonal imbalance can interfere with the growth and release of eggs from the ovaries (ovulation) and cause irregular periods, acne, and excess hair growth on the face and body. Also Read - Ayurvedic treatment of PCOS: Herbs used to manage the symptoms

Women with PCOS are also often insulin resistant, a risk factor for pre-diabetes and type 2 diabetes. Insulin resistance is when your body cant respond properly to the insulin it makes and cant use glucose from your blood for energy. Over time this results in elevated levels of glucose in the blood and increases risk for type 2 diabetes. Also Read - Beat PCOS with these easy lifestyle changes

Insulin resistance is believed to play a role in causing PCOS as well as exacerbating its symptoms.

The pancreas, a gland in the abdomen, produces insulin in response to increased blood levels of glucose that comes from the food you eat. Insulin allows the cells throughout the body to absorb glucose which serves as energy to them. When someone has insulin resistance, the cells do not respond to insulin as efficiently as it should be, leading to high glucose levels in the blood. Insulin resistance usually precedes type 2 diabetes.

Insulin resistance may also contribute to inflammation and other metabolic complications associated with PCOS. However, the relationship between these two conditions are not very clear yet. Moreover, not all women with insulin resistance develop PCOS.

Some experts opine that obesity-associated insulin resistance alters the function of the hypothalamus, a part of the brain that helps control the release of hormones from the pituitary gland. This leads to increased production of androgenic hormones, which contribute to PCOS.

As insulin is an appetite stimulant, an increase in appetite could be a symptom of insulin resistance. This may explain why women with PCOS experience frequent cravings for sweets. An increase in appetite may lead to weight gain, which in turn increases risk of obesity, cardiovascular disease and diabetes.

Insulin resistance may cause high blood sugar levels for a prolonged time after eating. This can lead to symptoms like decreased energy, increased thirst, and frequent urination. Over time, it can lead to type 2 diabetes and other metabolic conditions.

Therefore, women with PCOS are recommended to regularly check for insulin resistance. Early detection can allow earlier initiation of treatment. Fasting Blood Glucose Test: Glucose Tolerance Test: Glycosylated Hemoglobin A1C are common tests used to screen for insulin resistance.

If you have PCOS, incorporating some healthy lifestyle habits including daily exercise and a well-balanced diet can help prevent developing diabetes. Cut down on fats and sugars, eat more whole grains, fruits, and vegetables.

Being overweight is associated with an increased risk of developing insulin resistance and type 2 diabetes. Insulin resistance also runs in families. But no matter what caused the insulin resistance, losing weight will help improve symptoms associated with it.

Published : November 11, 2020 7:26 pm

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PCOS and Diabetes: Whats the connection? - TheHealthSite

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It's been a quite a week and an extraordinary year. If you're feeling anxious, know you're not alone. We asked the experts to share practical tips for how to cope in these difficult times.

This year has put all of us through the emotional wringer. And if youre struggling to cope with it all, well, youre not alone.

A report released in October by the American Psychological Association revealed nearly one in five adults (19 percent) believe their mental health is worse than this time last year. Unfortunately, that percentage may only increase in the coming months as the pandemic continues to worsen in Colorado and across the country.

Were forecasting a rough mental health winter for a lot of people, says Justin Ross, clinical psychologist at the UCHealth Integrative Medicine Center in Central Park. The good news: There are simple steps we can take to make 2020 (and beyond) feel a bit more bearable. We asked Ross and two other local mental health experts how Coloradans can best cope.

If you or someone you know is in immediate crisis, call Colorado Crisis Services at 1-844-493-8255, or text TALK to 38255.

Feel your feelings. Then, track them. First things first: Give yourself permission to feel crappy right now. What were feeling is completely normal and 100 percent human, explains Ross. Were supposed to be anxious and upset and scared and sad when our lives are disrupted on such a high magnitude. Its also important to label what youre feeling, he adds, as doing so can lessen the intensity of your emotions and provide the space you need to actually deal with them. Saying something as simple as Im noticing Im feeling anxious is a good place to start.

From there, pay close attention to your daily thoughts and actionsa process Ross describes as tracking and for which there are appsto see if you can correlate behavioral habits with mood and thus make tweaks to your routine as needed. Its imperativeespecially as we enter a colder, darker season, that were paying really close attention to maintaining healthy thoughts and healthy daily behaviors, he says.

Accept what you cant control. A big reason for our collective anxiety right now is that many stressorsthe pandemic, the election, the recessionare out of our control. And while these circumstances are undoubtedly undesirable, saying things like This is so awful and I cant cope isnt going to help. In fact, that rhetoric will probably make you feel worse, says clinical psychologist Antonia Pieracci, PhD, co-founder of CBT Denver. Instead, try to accept the stressors that are out of your influence (like the fact that we dont know when the pandemic is going to end) and redirect your energy to things you can control (for example, goals you want to accomplish in the upcoming months). Doing so will help you feel empowered and like youve regained agency over your life.

Practice gratitude. Theres a lot of strong research that shows practicing gratitude can enhance your well-being, says Jenn Leiferman, PhD, director of the Rocky Mountain Prevention Research Center and a founder of the Population Mental Health and Wellbeing Program at the Colorado School of Public Health. This isnt about donning rose-colored glasses, but instead involves reflecting on whats going well in your world as a way to shift into a more positive mindset. Simple gratitude exercises, like listing three things youre grateful for everyday, can be really powerful, says Leiferman.

Find safe ways to connect. Social interaction is critical to our health. We need other people to function well, to survive, says Pieracci, referencing research that shows people who have active social lives live longer, are at less risk for dementia, and have better physical and mental health. Connectedness helps protect us during times of uncertainty, adds Leiferman, so its important to stay in regular touch with your community right now. If in-person get-togethers arent possible because of the pandemic, schedule weekly phone calls, commit to regular Zoom dates, or keep in touch the old-fashioned way by sending letters and photos in the mail. Even going for a walk and smiling at passersby can help, says Pieracci.

Try something new. Feeling despondent? Start a new hobby that engages your brain, suggests Pierraci. Doing something novel like learning a new language or practicing a new sport can help redirect your attention in a healthy way. It will also keep things feeling fresh and give you something to focus on in the months to come, adds Ross.

Meditate. Meditation, Ross explains, can help alleviate the physiological symptoms of anxiety, which include elevated heart rate, rapid breathing, and surges of adrenaline and cortisol. Meditation can also help reorient your thoughts, he adds. Dont know how to meditate? Learn with an app. Ross recommends Headspace, Calm, 10 Percent Happier, and Insight Timer (on which he is an instructor).

Limit doom scrolling. Its important to stay informed on whats going on in the world, but constantly consuming the news can increase feelings of hopelessness, says Pieracci. To strike a healthy balance, set both a time and a source limit for your social media consumption, suggests Ross. For example, commit to spending just five minutes every hour on social media and visit just two platforms during that time.

Get outside. Spending time in nature can be very therapeutic, and you dont need to drive anywhere to get your fix, says Leiferman. Go on a walk in your neighborhood, visit a local park, or simply sit in your backyard. While youre there, Leiferman suggests asking yourself: What are two things Im hearing right now? Two things Im seeing? Two things Im smelling?Turning your attention to your senses can help clear anxious thoughts and center your mind in the moment.

Exercise and practice basic self-care. Protect your well-being this winter by exercising, eating healthy, limiting alcohol consumption, and getting enough sleep, says Leiferman. Exercise, in particular, can have a powerful effectPieracci cites a 2019 study published in Depression and Anxiety that concluded exercising in any form for three hours a week may lower risk of depression. So if you find your mood dipping, sneak in some movement. It neednt be a full-blown workout; small bursts of activity, like jogging up and down your stairs a couple times, walking your dog an extra mile, or having a dance party in your kitchen, can make a difference.

Weve all been a little (or a lot) on edge this year. But if your mental health has tanked to the point where its interfering with relationships or your ability to perform your job or complete school work, seek professional help, advises Pieracci. You should also talk to someone if you feel like youre suffering so much internally that youre barely able to hold things together, she adds. Yet another sign you should connect with a pro is if your mental health has notably nosedived and you just cant seem to get back to normal, says Ross.

Not sure where to turn? Consider Energize Colorado, an organization that contracts with therapists (including Pieracci) to offer free and low-cost therapy sessions to people who would not otherwise be able to afford such services right now. Their website also contains links to mental health support groups, a directory of Colorado-based mental health professionals, educational resources, and more. The Happiness Trap is another online resource with free mental health videos and resources, says Pieracci. And the Colorado School of Public Healths Population Mental Health and Wellbeing website, recommended by Leiferman, contains educational content and links to community resources.

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The Mental Health Advice We All Need Right Now - 5280 | The Denver Magazine

The global nutrigenomics testing market is estimated to surpass $1,079.9 million by 2027, exhibiting a CAGR of 13.0% from 2020 to 2027.

The report aims to offer a clear picture of the current scenario and future growth of the global Nutrigenomics Testing market. The report provides scrupulous analysis of global market by thoroughly reviewing several factors of the market such as vital segments, regional market condition, market dynamics, investment suitability, and key players operating in the market. Besides, the report delivers sharp insights into present and forthcoming trends & developments in the global market.

The report articulates the key opportunities and factors propelling the global Nutrigenomics Testing market growth. Also, threats and limitations that have the possibility to hamper the market growth are outlined in the report. Further, Porters five forces analysis that explains the bargaining power of suppliers and consumers, competitive landscape, and development of substitutes in the market is also sketched in the report.

For More Detail Insights, Download Sample Copy of the Report at: https://www.researchdive.com/download-sample/526

The report reveals various statistics such as predicted market size and forecast by analyzing the major factors and by assessing each segment of the global Nutrigenomics Testing market. Regional market analysis of these segments is also provided in the report. The report segments the global market into four main regions including Asia-Pacific, Europe, North America, and LAMEA. Moreover, these regions are sub-divided to offer an exhaustive landscape of the Nutrigenomics Testing market across key countries in respective regions. Furthermore, the report divulges some of the latest advances, trends, and upcoming opportunities in every region.

Furthermore, the report profiles top players active in the global Nutrigenomics Testing market. A comprehensive summary of 10 foremost players operating in the global market is delivered in the report to comprehend their position and footmark in the industry. The report highlights various data points such as short summary of the company, companys financial status and proceeds, chief company executives, key business strategies executed by company, initiatives undertaken & advanced developments by the company to thrust their position and grasp a significant position in the market.

RESEARCH METHODOLOGY

The research report is formed by collating different statistics and information concerning the Nutrigenomics Testing market. Long hours of deliberations and interviews have been performed with a group of investors and stakeholders, including upstream and downstream members. Primary research is the main part of the research efforts; however, it is reasonably supported by all-encompassing secondary research. Numerous product type literatures, company annual reports, market publications, and other such relevant documents of the leading market players have been studied, for better & broader understanding of market penetration. Furthermore, medical journals, trustworthy industry newsletters, government websites, and trade associations publications have also been evaluated for extracting vital industry insights.

Connect with Our Analyst to Contextualize Our Insights for Your Business:https://www.researchdive.com/connect-to-analyst/526

KEY MARKET BENEFITS

KEY MARKET SEGMENTS

The global Nutrigenomics Testing market is segmented on the basis of the following:

Global Nutrigenomics Testing Market By Applications:

Global Nutrigenomics Testing Market By Regions:

Top Leading key players stated in Global Nutrigenomics Testing Market report are:

Holistic Heal, GeneLink, Cura Integrative Medicine, Nutrigenomix, GX Sciences, Interleukin Genetics, NutraGene, Metagenics, Pathway Genomics, Salugen, Genelex.

The report also summarizes other important aspects including financial performance, product portfolio, SWOT analysis, and recent strategic moves and developments of the leading players.

Contact Us:

Mr. Abhishek PaliwalResearch Dive30 Wall St. 8th Floor, New YorkNY 10005 (P)+ 91 (788) 802-9103 (India)+1 (917) 444-1262 (US) TollFree : +1 -888-961-4454Email:[emailprotected]LinkedIn:https://www.linkedin.com/company/research-diveTwitter:https://twitter.com/ResearchDiveFacebook:https://www.facebook.com/Research-DiveBlog:https://www.researchdive.com/blogFollow us on:https://covid-19-market-insights.blogspot.com

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Development Trends: Nutrigenomics Testing Market by Top Key Players, Applications and Forecast to 2020-2027 - Zenit News

A burp is a common sign that you're, well, experiencing some gas. Chest pain, on the other hand, is a gas symptom that's way less discussed.

"Gas can cause more than just pain in the belly. Gas can be described as a stabbing pain or tightness in the chest, which mimics chest pain," Dr. Monisha Bhanote, MD, FCAP, an integrative medicine physician, said.

According to Dr. Bhanote, gas is created in the body two ways: by swallowing air and through the digestive process.

When one eats or drinks too quickly, they can swallow air, which may lead to gas accumulation in the stomach; so, eating slower could help, she explained.

As for digestion, Dr. Bhanote said that not all of the sugar, starch, and fiber one consumes is broken down in the small intestine. It passes onto the large intestine, where bacteria further breaks it down into carbon dioxide, oxygen, nitrogen, hydrogen, and methane, which eventually leaves the body.

"Certain foods may also increase gas in individuals. This varies based not only on the food but on the bacterial colonization of the individual's gastrointestinal tract. Common culprits may include cruciferous vegetables, such as broccoli and cabbage [and] whole grains, as well as dairy products, soft drinks, beans, and some fruits."

Those experiencing chest pain should always consult a doctor about a diagnosis and treatment Dr. Bhanote stressed this if your gas is persistent and severe enough to affect your daily activities or cause changes in bowel movements, constipation, diarrhea, nausea, vomiting, or bloody stools. And if you're experiencing prolonged abdominal or chest pain that is out of the ordinary, Dr. Bhanote said to seek immediate care.

One topic worth discussing with your doctor is how to reduce gas by adjusting your eating habits. Dr. Bhanote suggested exploring possible food intolerances and eliminating unnecessary contributors to gas production, like carbonated beverages and sugar substitutes.

Slowing down when eating, avoiding drinking through a straw, and passing on chewing gum are easy ways to avoiding swallowing access air, she added.

And if you're unable to prevent gas from building up, there are some holistic approaches you can take (with a doctor's permission!) to feel better.

"Some herbal teas can aid in the digestive process and reduce gas. These may include any combination of ginger, peppermint, chamomile, or anise."

Additionaly, you can drink a glass of water with added apple cider vinegar before a meal to help prevent gas and bloating, Dr. Bhanote said. Getting active after a meal can also help by moving nutrients through your body more efficiently.

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Yes, Gas Can Cause Chest Pain Here's What You Need to Know - POPSUGAR

Trusted Business Insights answers what are the scenarios for growth and recovery and whether there will be any lasting structural impact from the unfolding crisis for the Complementary And Alternative Medicine market.

Trusted Business Insights presents an updated and Latest Study on Complementary And Alternative Medicine Market 2020-2029. The report contains market predictions related to market size, revenue, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing the key driving and restraining forces for this market, the report also offers a complete study of the future trends and developments of the market.The report further elaborates on the micro and macroeconomic aspects including the socio-political landscape that is anticipated to shape the demand of the Complementary And Alternative Medicine market during the forecast period (2020-2029).It also examines the role of the leading market players involved in the industry including their corporate overview, financial summary, and SWOT analysis.

Get Sample Copy of this Report @ Complementary And Alternative Medicine Market 2020 and Forecast 2021-2027 Includes Business Impact Analysis of COVID-19

Report Overview: Complementary And Alternative Medicine Market

The global complementary and alternative medicine market size was projected at USD 58.1 billion in 2019, registering a CAGR of 18.8% over the forecast period 2021-2027. Yoga, meditation, magnetic intervention, acupuncture, and complementary wellness treatments are gaining immense popularity across developed countries. This can be attributed to wide acceptance of these alternative treatments among general population, further causing an upswing in the number of yoga studios, meditation centers, spas, and complementary wellness facilities.

Government initiatives play a pivotal role in boosting the adoption of Complementary and Alternative Medicine (CAM). In addition, increased funding, establishing government facilities dedicated to complementary therapies, and the expensive nature of conventional treatment options are some of the secondary factors encouraging companies to invest in the market for complementary and alternative medicine.

Regional government authorities and players are focusing on strengthening medical tourism associated with complementary and alternative medicine. Government authorities in India are heavily investing in the development and standardization of facilities pertaining to complementary medicine in recent years. For instance, Ministry of Ayush is set up by national authorities to govern research, development, education, and other facilities pertaining Ayurveda, yoga, naturopathy, and homeopathy.

Alternative medicine is expected to become more mainstream in the coming years, especially in developed countries. This can be attributed to a new acceptance displayed by physicians and doctors in U.S. toward alternative philosophies and treatments that were conventionally excluded from mainstream medicine.

Advent of integrative medicine has proven to be profitable for propelling the penetration of complementary and alternative treatment. Professionals state that integrative medicine has the potential to address an array of patients influences, including environmental, emotional, physical, and spiritual.

Robust investments in this direction began in 2016 and have continued since then. For instance, Andrew Krupp, a late philanthropist granted approximately USD 30 million to the Center for Integrative Medicine, California for a research program. This program was designed to analyze the potential benefits of exercise, diet, and natural therapeutics in the treatment of various chronic ailments, such as cancer and heart disease.

Intervention Insights: Complementary And Alternative Medicine Market

Gradual expansion of alternative interventions, such as energy healing, is expected to drive the complementary and alternative medicine market. For instance, The Healing Company headquartered in England exhibits a diverse portfolio of complementary therapies, including reflexology, reiki, and havening techniques. Havening is a breakthrough complementary therapeutic approach developed to treat patients suffering from trauma and mental stress.Furthermore, magnetic therapy is gaining significant traction among professionals operating in the field of traditional medicine. Still in its nascent stage, a few clinical trials have stated the potential benefits of magnetic field therapy in pain management, which is set to boost its penetration across medical settings.

For instance, Memorial Sloan Kettering Cancer Center, a research institution and cancer treatment center offer magnet therapy using different products, including Bioflex magnets, magnet therapy mattresses, and MagnaBloc.

Distribution Method Insights: Complementary And Alternative Medicine Market

The direct sales distribution segment is the largest contributor to the revenue generated by the global market for complementary and alternative medicine. This can be attributed to the fact that most frequently performed complementary and alternative therapies require direct interaction with the patient.

These therapies include naturopathy, energy healing, magnetic intervention, and acupuncture, associated with direct sales by practitioners to the patients. Also, soaring demand achieved by distance correspondence-based alternative medicine has contributed to the highest CAGR of this segment.

Majority of the practitioners operate at micro business level and are more inclined toward achieving the required therapeutic expertise as compared with their marketing skills. However, growing medicinal and economic significance of complementary and alternative medicine is expected to enhance the distribution methods targeted toward strengthening revenue generation.

Regional Insights: Complementary And Alternative Medicine Market

Europe is expected to account for the highest revenue throughout the forecast period followed by the Asia Pacific region. Wide acceptance of alternative treatment approaches and rising patient preference toward the same is boosting the regional market for complementary and alternative medicine.

Expanding research efforts with regard to CAM have been witnessed in U.K.; this is also supplemented by stringent regulations and laws imposed on the practitioners to ensure appropriate administration of complementary and alternative medicine therapies. The National Institute for Health and Care Excellence (NICE), U.K., recommends the use of manual therapy in pain management, acupressure to reduce morning sickness, and Alexander technique for the treatment of Parkinsons disease.

The fact that ancient medicine originated in the Asia Pacific countries, including China, Japan, and India, offers regional companies with a competitive edge in terms of CAM expertise and education. Popular complementary and alternative medicine therapies introduced by Chinese include Reiki, tai chi, and energy healing, whereas yoga, chakra healing, and Ayurveda have originated in India.Complementary And Alternative Medicine Market Share Insights

Some of the major players include

The market for complementary and alternative medicine is largely fragmented owing to presence of numerous medium and large-sized players. Several strategic initiatives such as portfolio expansions and marketing programs have been adopted by market players to maintain their market presence.For instance, in July 2019, Columbia Nutritional developed a novel process with multi-phase onboarding aspect suitable for efficient launch of latest products online while meeting customers specifications. This strategy was targeted toward maintaining Minimum Order Quantity (MOQs) that would further enhance the quality of service offered.

On the other hand, in December 2018, Ramamani Iyengar Memorial Yoga Institute arranged an exposition for 12 days, wherein 1,200 students from approximately 53 countries were involved. This exposition helped promote the practice of yoga among the youth.This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2027. Trusted Business Insights has segmented the global complementary and alternative medicine market report based on intervention, distribution method, and region:

Intervention Outlook (Revenue, USD Billion, 2016 2027)

Distribution Method Outlook (Revenue, USD Billion, 2016 2027)

Looking for more? Check out our repository for all available reports on Complementary And Alternative Medicine in related sectors.

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By: Lifestyle Desk | New Delhi | November 9, 2020 10:00:56 amHere's why walking barefoot on earth is good for your health. (Source: Getty Images/Thinkstock)

Have you ever thought why it feels good to walk in a lush green garden or when you are at a hill station or the beach? That is simply because you are in close proximity to nature and it is said that the closer you are with nature, the happier and healthier you become. And one such practise that helps you connect with nature is grounding or walking barefoot on the ground or clean grass. It is a therapeutic lifestyle change if you have access to a garden or clean soil, says Luke Coutinho, Holistic Lifestyle Coach Integrative Medicine.

All living creatures on earth, besides adults, maintain their contact with the soil. Our modern lifestyle separates humans from such contact. We sleep on beds, walk with shoes, etc., and this lost contact with earth or nature, in general, is why most of us are unhappy and ungrounded. Today, there are scientific studies proving the disconnect between nature and humans as a major contributor to physiological dysfunction and unwellness, he tells indianexpress.com.

ALSO READ | Fasting is not starvation or a fad, it is a discipline: Luke Coutinho

However, grounding doesnt mean sleeping on the floor, it is about having a little exposure to earth and soil. Below, he shares some benefits of the practice.

It can make one feel refreshed and more in sync with nature

Grounding is one of the best ways to connect with mother earth and nature. Walking barefoot on earth can give pleasure and peace if done mindfully. This is not possible on cement or tiled surfaces.

It develops mindfulness and awareness

Walking barefoot on the ground helps us tune into our awareness and makes us alert.

Reduces blood pressure

Walking barefoot on the ground can help us feel relaxed, calm and safe almost instantly, thereby having a positive effect on blood pressure. In naturopathy, it is recommended to walk for 10-15 minutes barefoot to the normalise blood pressure.

Reduces inflammation and pain

Earth has a special electrical power which gives vital force to any person walking barefoot on it. Science says that walking barefoot helps us absorb negative ions from the earth, and due to the direct physical contact, it allows a vast supply of electrons from the surface of the earth, similar to what lighting up Himalayan pink salt lamps do.

Boosts immunity and gut health

Exposing yourself to the soil and ground can benefit as the powerful microbes found in soil help build immunity naturally. Microbes enter our body through our skin, from under our nails and feed the good bacteria in our gut microflora making us stronger and healthier, thereby boosting our immune system. We live in a world thats full of antimicrobial handwashes, soaps chemically-laden shampoos, which is not a bad thing, but it wipes us off necessary microbes that also exist on our skin. Grounding can help us absorb some of the good bacteria.

Its a great acupressure

Walking barefoot helps activate several acupressure points on our foot due to its uneven surface. This can have a positive impact on our entire body.

Can improve feet hygiene

Our skin surface houses thousands of bacteria and when the bad bacteria outweigh the good, it could lead to bad odour. Mud is known to pull out these toxins and bad odour. This is why people in rural areas clean their houses by applying a mix of earth and water on the floors and walls and even wash their hands with mud after answering natures call. Things which are rotten are covered with earth.

Much in the same way, walking barefoot can pull out toxins from the soles of our feet and increase the number of good bacteria on the skin surface, thereby boosting foot hygiene. This, again, isnt possible when we wear shoes all the time.

There is a common notion that walking barefoot can induce cold and cough. However, this is incorrect. Ancient sages and holy men traditionally walked barefoot and gave training to their disciples to do the same. Whether you catch a cold or not, is on your immunity, mentions Coutinho.

Hence, it is a good idea to adopt this practice especially if you have access to nature or do it once in a while whenever you get a chance.

Note: Please practice caution in case of diabetes, as any cut or injury due to walking barefoot on soil or grass can lead to further complications.

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Why walking barefoot on soil is good for you; a lifestyle coach explains - The Indian Express

Life as a new mom is hard as it is. Factor in a pandemic, spending months indoors, and having to wear a face mask to do basic things like head to doctor appointments and grocery store run, and it's completely understandable if your new mom friends are ready to pull their hair out. Now is the perfect time to show them just how solid of a support system they have in you with a gift to help ease their day-to-day challenges.

While they may not be dealing with the woes or homeschooling just yet, learning the ins-and-outs of caring for a new baby, all while trying to maintain some semblance of a self-care routine is a hell of a lot of work. Show them some love with these helpful items that'll make life as a new mom a lot more comfortable.

Between the pregnancy acne and chafing from nursing, dealing with pre- and post-baby skin can feel like it's on a wild roller coaster ride. Help your mom friends and family keep their skin soft, soothed, and chap-free with the help of Mutha Body Butter, a whipped blend of moisturizing shea, cocoa, and mango butters. Or for those areas that need a bit more love, Lano's Golden Dry Skin Salve is a multi-purpose balm that heals cracked, lips, hands, and heels.

And with its mousse-like texture and cocoa butter and jojoba oil-laced formula, the Allure Best of Beauty-winning Ever Lavish Ultra Rich Body Butter is an even more luxurious moisturizing gift to give.

The Conscious Coconut Home Bath Bundle comes with a jar of organic coconut oil and a dry brushing tool to exfoliate rough skin. New moms in your life who are already familiar with the fan-favorite Bio-Oil original formula will likely be into the brand's newest launch, the Bio-Oil Dry Skin Gel. Thirty years after the launch of its first product, Bio-Oil introduced a gel-to-oil formula with glycerin and urea to help moisturize intensely dry skin. It's a perfect addition to any unpredictable, post-pregnancy skin-care routine.

The Burt's Bees Tips and Toes Kit Gift Set was made especially for dry extremities. The six-piece set has a hand cream, foot cream, multi-purpose salve, cuticle cream, lip balm, and travel-size hand cream all with skin-nourishers like sweet almond oil and vitamin E.

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23 New Mom Gifts Thatll Make The First Year Less Stressful - Allure

Two European leaders in biopharma and integrative software are working together to advance drug discovery

Synthace Ltd and Ipsen, a global biopharmaceutical company focused on innovation and specialty care, have partnered to accelerate development of novel biotherapeutics targeting multiple therapeutic areas, including oncology, endocrinology, pain management, regenerative medicine and rare diseases. Ipsen has automated design and construction of therapeutic candidates using Synthaces integrative software platform, Antha. The process aims to speed up biotherapeutic candidate entry into the screening pipeline and shorten development time for treatment of diseases via targeted secretion inhibition.

Ipsen has developed novel biotherapeutic molecules, called Targeted Secretion Inhibitors TSIs. (TSIs are a fusion of select parts of the botulinum neurotoxin with another protein domain) to redirect its mode of action, resulting in a unique targeted therapeutic. The design and construction of TSIs is both labor intensive and manually complex, typically taking 30 days to develop between 24-48 constructs which then go on to therapeutic screening.

The Ipsen R&D team required a solution to increase throughput and efficiency of its TSI generation and screening pipeline, while utilizing its Type IIs construct assembly method. They looked to fellow innovators Synthace, whose flexible and integrative software Antha has built-in workflows for automating processes such as Type II construct assembly, bacterial transformation, plating, data generation and analysis.

Synthaces Antha platform allowed the Ipsen team to plan, simulate, and test their assemblies in silico before executing the protocol. The partnership of Antha and Ipsen produced approximately 90 constructs five times faster than previous methods, substantially increasing the number of molecules entering the screening cascade. Antha was also able to increase efficiency by re-using core DNA building blocks for multiple construct assemblies, resulting in a 10-fold reduction in costs associated with DNA synthesis.

Dr Karen Bunting, Director of Protein Science at Ipsen said, The development of novel biotherapeutics like TSI is key to treating debilitating illnesses across multiple therapeutic areas. The first step in this is generating and screening high-quality molecules as therapeutic candidates. Using Antha, our team increased throughput at this crucial step, allowing us to design, construct, and screen novel TSI candidates rapidly and helping to advance our therapeutic solutions.

Drug discovery is a costly and laborious process where thousands of candidates are generated, screened and validated, but only a select few are chosen to move forward in the pipeline. Pharma companies are turning to automation and software to aid in the design, construction and screening of these compounds, reducing costs and increasing efficiency without compromising on quality.

To achieve this, biopharmaceutical companies like Ipsen are partnering with specialists in integrating the digital and physical aspects of R&D, providing an easy-to-use interface between scientists, design software, automated devices, and data handling downstream. This flexible, integrated approach to the discovery process has clear advantages in boosting efficiency at the earliest stages of drug development, with the ultimate goal of making more effective treatment options available to patients sooner.

Tim Fell, CEO of Synthace concluded, We are thrilled to see our Antha platform applied to develop new biotherapeutics. Antha has accelerated Ipsens TSI construction and screening programme while reducing costs and the time scientists spent in the lab. Automating processes like these allows scientists to focus on experimental design and data analysis rather than liquid handling, enabling them to create more beneficial therapeutics for patients.

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Synthace joins Ipsen to accelerate therapeutic development - SelectScience

Dana Laake and her special guest Dr. Liz Lipski will discuss the keys to optimal digestive wellness.

Dr. Liz Lipski holds a PhD in clinical nutrition and is a Fellow of the American College of Nutrition (FACN). She has two board certifications in clinical nutrition (CNS and BCHN) and one in functional medicine (IFMCP), and is on the faculty for The Institute for Functional Medicine and the Metabolic Medicine Institute fellowship program. Dr. Lipski is on the board of the American Nutrition Association, and advisory boards for the International Association of Health Coaches and the Autism Hope Alliance. She is a professor and director of academic development for graduate programs in clinical nutrition at Maryland University of Integrative Health, and the owner of the Innovative Healing Academy.She has been a co-author in peer-reviewed papers and is the author of three books, Digestive Wellness, Digestive Wellness for Children and Leaky Gut Syndrome, and a video course, The Art of Digestive Wellness.

Continued here:
The Keys to Optimal Digestive Wellness - Federal News Network

This year has exposed the vulnerabilities of traditional fee-for-service practices in ways we could never have foreseen, says Bauer. And 2020 has also underscored the resilience and rewards of the Specialdocs model of personalized medicine and inspired rising numbers of physicians to consider this beneficial alternative for themselves and their patients. At this pivotal point in American healthcare, we are privileged to share with Concierge Medicine Forum attendees our collective experience and first-person stories of transformation from our network of dedicated doctors.

Michael Tetreault, CMF organizer and editor of Concierge Medicine Today, says: The virtual format enables us to host a more diverse gathering of healthcare professionals than ever before, and offer 24/7 on-demand access to insights from the industrys most creative minds. Were thrilled to feature groups like Specialdocs, pioneers and continual innovators in the concierge medicine space.

Specialdocs will be featured at events including: (all ET)

Thursday, Nov. 12th Pre-conference workshop

Friday, Nov. 13th

After 2 pm

Saturday, Nov. 14th

Since 2002, concierge medicine transition and management experts Specialdocs Consultants have helped physicians nationwide transform their practices with a uniquely customized and sustainable concierge model.

Contact: Mindy Kolof, [emailprotected]

SOURCE Specialdocs Consultants

https://specialdocs.com

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Specialdocs Informs and Inspires at Concierge Medicine Industry's Signature Event Nov. 12th 14th - Virtual-Strategy Magazine

Whos the chica? my nosy neighbor asked when he saw Natasha Khallouf climb into her car and take off. I wanted to tell him to mind his own business. Instead, I said, Shes a doctor. No doubt about it, Dr. Khallouf stood out in my backyard. Her cannabis brand, Mindzright, also stands out in Sonoma County, as does her cannabis farm,Agricola Flower.

A Doctor of Acupuncture and Chinese Medicine (DAOM), and an L.Ac, Khallouf runs a Sebastopol clinic, On Point Integrative, where she integrates acupuncture with herbs and helps educate patients about nutrition and healthy lifestyles.

I think of her not only as a doctor of Chinese medicine and a marijuana grower, but also as a curandera, which translates from Spanish to English as healer. Curanderos often provide the first line of defense against aches, pains, colds and the blues throughout Latin America and in parts of the U.S. In some ways, Western medicine is still catching up with curandero lore and folk remedies, including the use of cannabis.

Raised in a trilingual home in SoCalher mother was born in Nicaragua, her father in LebanonKhallouf cut her eye teeth on the streets of L.A. She began to use cannabis at an early age and was fortunate, she tells me, to encounter and explore many of the citys alternative communities, hear all kinds of musicincluding reggae and classic rockand rub shoulders with intellectuals.

Along the way to becoming a doctor, she learned cannabis has been cultivated for thousands of years. Indeed, it shows up prominently in Shen Nong Ben Cao Jing, the classic Chinese text on herbs, agriculture and acupuncture which was written nearly 2,000 years ago and is still used as a reference guide.

In 1996, when California voters approved Prop. 215, which ushered in the era of medical marijuana, Khallouf stepped into the breach to link cultivators, patients and health care providers, and offered helpful suggestions about the best strains for particular ailments, how much to use and how often and what methods were the most effective.

When the pandemic arrived this winter, followed by fires, heat and smoke, Khallouf refocused her practice and began to devote herself to the care of the undocumented and farm workers at risk.

As a single woman with two children, she says she can feel marginalized in Sonoma County, even among the cannabis crowd. She draws strength from her inner reserves and the communities she serves. Id go to her clinic and ask for acupuncture and herbs, both of which I have made use of for decades. One day my nosy neighbor might say, You rock, chica.

Jonah Raskin is the author of Dark Past, Dark Future: A Tioga Vignetta Murder Mystery.

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The Healer Is In | Rolling Papers - North Bay Bohemian

The promise of treatment or cure of many chronic illnesses has led to thousands of patients worldwide travelling internationally to receive Stem Cell Treatment. This is what has come to be known as stem cell tourism.

The medical facilities offer Stem Cell Treatment to treat conditions like Spinal Cord Injury, Alzheimers and Parkinsons by introducing stem cells into the patients bodies. The stem cells would then develop into new tissue or cells and repair damage caused by illness or injury.

Such clinics are mainly spread across Asia, Eastern Europe and South America. Patients from the West the United States, Western Europe and Australia travel to these facilities to receive treatment. The main reason for this travel is that the approval of drugs in the East is faster and more accommodative than in western countries.

One of the Bloomberg Businessweek publications told the story of an American man who travelled to China to receive treatment for paralysis caused by severe Spinal Cord Injury.

24-year-old Chuck Melton suffered a head injury and a severe spinal cord injury after a diving accident. He remained paralysed from the chest down for five years with no hope for a cure in the US. He then opted to travel to China to receive Stem Cell Treatment.

He was injected with stem cells into his spine and was showing significant improvement a week later. His doctors noted that the involuntary muscle spasms in his legs had stopped. He was also able to perspire for the first time since the injury. This allowed him to spend time outdoors without endangering his life.

Five years after the treatment, he may not be able to walk but his quality of life has improved greatly. Before the procedure, Melton has told the media that he hoped to walk again but would be satisfied with any improvement in his condition.

Many conventional researchers may fault the treatment options offered by Stem Cell Treatment facilities in the East for lack of orderly research but for the patient whose time is limited, it is their only hope. With success stories such as Meltons, stem cell researchers are willing and have come out to defend their work.

The researchers have unequivocally stated that conventional medicine is not the only way to treat patients. It was noted that even some crucial treatment procedures in modern medicine bypassed the customary approval route. One such procedure is heart transplantation, it was quickly co-opted by heart surgeons worldwide (before orderly research) after Dr. Christiaan Barnards first successful procedure.

H/T:Stem Cell Tourism

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Stem Cell Tourism: Providing Hope For Treatment Away From ...

Stem cell therapy has the potential to improve the quality of life for many patients with chronic diseases such as; diabetes, Parkinsons disease, Alzheimers disease, rheumatoid arthritis and many other inflammatory diseases. Esthetic treatments like anti-aging options, weigh-loss, and hormone treatments are also showing great potential in the wellness/medical tourism field in Costa Rica.

McKinsey and Company, an influential global consulting company, reported that medical tourists from the United States and Canada, prefer Latin American countries including Costa Rica because of the short travel time, affordable costs, and the opportunity to enjoy a memorable vacation.

There are direct flights from many cities in the United States and Europe; it is only a 2.5-hour flight from Miami, Florida to San Jose, Costa Rica or a 3.5-hour flight from Houston, Texas. TheStem Cells Transplant Instituteis located close to the airport in Escazu, San Jose.

Treatment packages include a two-night stay at the beautifulIntercontinental Hotellocated just minutes from the clinic as well as shopping and restaurants. Another option for accommodations for patients to stay in would be theHotel Quality Real San Jos. From either location, you could enjoy the rich culture and heritage of San Jose by taking a VIP bus tour or, if you are feeling a bit more adventurous, venture out on your own to Avenida Central and visit the many museums, parks, shops and restaurants located along the avenue.

Traveling to Costa Rica for a stem cell treatment allows you the opportunity to explore a beautiful and diverse country. Approximately 2 million tourists come to explore the beauty of Costa Rica every year; they come to hike the rainforests, lounge on thebeachor relax in the hot springs. Costa Rica is also a bird watching paradise with more than 850 species, more species than the United States and Canada combined. However, if you are just looking to relax, the country also has some amazing spas located in the city or surrounded by the beauty and solitude of the rain forest. Many resorts specialize inyoga and wellness retreats, spas, and weight-loss programs. The Nicoya Peninsula around Tambor, Montezum and Mal Pais is largely undeveloped and a great place to go on some nature tours. For an ICT approved, excellent travel agency, for complete travel packages, contactCosta Rican Trails. Go to https://bancoinfo.co.cr for all bank locations and hours.

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Medical Tourism - Stem Cells Transplant Institute

NEW YORK, Nov. 4, 2020 /PRNewswire/ --

Anti-Aging Market Research Report: By Product (Anti-Wrinkle, Hair Color, Ultraviolet Absorption, Anti-Stretch Mark), Treatment (Hair Restoration, Anti-Pigmentation, Adult Acne Therapy, Breast Augmentation, Liposuction, Chemical Peel), Demography (Generation X, Baby Boomers, Generation Y) - Global Industry Analysis and Growth Forecast to 2030

Read the full report: https://www.reportlinker.com/p05982459/?utm_source=PRN

The major driving factors for the anti-aging market are the rising number of awareness-raising seminars and conferences, surging geriatric population, increasing disposable income, technological advancements, expanding medical tourism sector, and escalating cosmetic surgery volume. These factors will lead to an increase in the industry revenue from $191.5 billion in 2019 to $421.4 billion in 2030, at an 8.1% CAGR during 20202030 (forecast period). Products used to diminish the signs of aging are easily available at physical stores and online portals.

A key factor aiding the anti-aging market advance is the rising number of seminars and conferences being organized to make plastic surgeons, students, and the general public about the advanced anti-aging treatments. For instance, the Aesthetic & Anti-Aging Medicine World Congress (AMWC) hosted by EuroMediCom (Informa Group) in April 2019 in Monte Carlo, Monaco, included five knowledge sharing and discussion sessions on anti-aging and aesthetics. Formerly, the Aesthetic & Anti-Aging Medicine World Congress 13th Edition was hosted in Thailand in September 2018 by the American Academy of Anti-Aging Medicine (A4M).

Another major reason the demand for anti-aging treatments and products is increasing is the booming geriatric population. The United Nations says that the number of people in the age group of 65 and above will surge from 703 million in 2019 to 1.5 billion by 2050. With age, people experience stem cell and fibrous tissue loss, which leads to dryness, wrinkles, sagging, and pigmentary alteration. Therefore, in order to continue looking young and attractive, the geriatric population regularly uses anti-aging remedies, which tighten and revitalize the skin, in addition to making people look young.

North America is the dominant region in the anti-aging market currently, owing to the rising plastic surgery volume and geriatric population. The UN expects the number of elderly people on the continent to increase to 96.2 million by 2050 from 59.9 million in 2019. This, coupled with the growing volume of plastic surgeries, is expected to result in a massive surge in the demand for various therapies and products that help people look young and aesthetically appealing.

Hence, as more people age and their awareness regarding how they can reverse or physically hide the effects of this process rises, the market will keep blossoming.

Read the full report: https://www.reportlinker.com/p05982459/?utm_source=PRN

About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

__________________________ Contact Clare: [emailprotected] US: (339)-368-6001 Intl: +1 339-368-6001

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Anti-Aging Market Research Report: By Product, Treatment, Demography - Global Industry Analysis and Growth Forecast to 2030 - PRNewswire

According to IMARC Groups latest report, titled Regenerative Medicine Market: Industry Trends, Share, Size, Growth, Opportunity and Forecast 2020-2025,. Looking forward, IMARC Group expects the global regenerative medicine market to continue its strong growth during the next five years.

Regenerative medicine refers to a field of biomedical sciences involved in restoring the structure and function of damaged cells, organs, and tissues. It includes the study of stem cells that are developed in laboratories and then safely inserted into the human body to regenerate damaged bones, cartilage, blood vessels, and organs. Cellular and acellular regenerative medicines are widely adopted in various clinical therapeutic procedures, including cell therapies, immunomodulation, and tissue engineering. They have the potential to treat various chronic diseases, including Alzheimers, Parkinsons, cardiovascular disorders (CVDs), osteoporosis, spinal cord injuries, etc.

Request for a free sample copy of this report: https://www.imarcgroup.com/regenerative-medicine-market/requestsample

Market Trends

The rising prevalence of chronic diseases and genetic disorders is primarily driving the demand for regenerative medicine across the globe. Moreover, the growing geriatric population who are more prone to musculoskeletal, dermatological, and cardiological disorders is also augmenting the need for regenerative medicines. Furthermore, several technological advancements in cell-based therapies have led to the adoption of 3D bioprinting techniques and artificial intelligence (AI), thereby further propelling the market for regenerative medicine. Moreover, regenerative medicine decreases the risk of organ rejection by the body post-transplant and increases the patients recovery speed, thereby gaining traction in numerous organ transplantation procedures. The increasing investments in extensive R&D activities in the field of medical sciences are expected to drive the market for regenerative medicine.

Regenerative Medicine Market 2020-2025 Analysis and Segmentation:

Competitive Landscape:

The competitive landscape of the market has been studied in the report with the detailed profiles of the key players operating in the market.

Some of these key players include:

The report has segmented the market on the basis of type, application, end user and region.

Breakup by Type:

Breakup by Application:

Breakup by End User:

Ask Analyst for Instant Discount and Download Full Report with TOC & List of Figure: https://bit.ly/2RAf08Y

Breakup by Region:

About Us

IMARC Group is a leading market research company that offers management strategy and market research worldwide. We partner with clients in all sectors and regions to identify their highest-value opportunities, address their most critical challenges, and transform their businesses.

IMARCs information products include major market, scientific, economic and technological developments for business leaders in pharmaceutical, industrial, and high technology organizations. Market forecasts and industry analysis for biotechnology, advanced materials, pharmaceuticals, food and beverage, travel and tourism, nanotechnology and novel processing methods are at the top of the companys expertise.

Contact US:IMARC Group30 N Gould St, Ste RSheridan, WY 82801, USAWebsite: https://www.imarcgroup.com/Email: [emailprotected]USA: +1-631-791-1145Follow us on twitter: @imarcglobalLinkedin: https://www.linkedin.com/company/imarc-group

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Regenerative Medicine Market 2020: Analysis, Top Companies, Size, Share, Demand and Opportunity To 2025 - Eurowire

DetailsCategory: DNA RNA and CellsPublished on Monday, 09 November 2020 18:03Hits: 291

NEW YORK, NY, USA I November 09, 2020 I Axovant Gene Therapies Ltd. (NASDAQ: AXGT), a clinical-stage company developing innovative gene therapies, today announced that the U.S. Food and Drug Administration (FDA) has lifted its clinical hold and cleared the Investigational New Drug (IND) Application to initiate a registrational study of AXO-AAV-GM2 gene therapy to treat patients with Tay-Sachs disease and Sandhoff disease. AXO-AAV-GM2 is the first investigational gene therapy to achieve IND clearance for Tay-Sachs and Sandhoff diseases. The Company received a letter from the FDA indicating that it has satisfactorily addressed all issues related to the clinical hold.

The IND clearance of AXO-AAV-GM2, the first potentially curative treatment for Tay-Sachs and Sandhoff diseases to enter the clinic, marks a seminal moment for the entire GM2 gangliosidosis community. Along with AXO-AAV-GM1 for GM1 gangliosidosis, todays announcement represents the second IND clearance for Axovants gene therapy pipeline in the last 12 months, said Gavin Corcoran, M.D., Chief R&D Officer of Axovant. AXO-AAV-GM1 and AXO-AAV-GM2 are the first gene therapies to enter active clinical development in their indications. Each program captures the essence of our mission to liberate patients from debilitating neurological diseases by rapidly advancing these gene therapy programs into clinical development. We look forward to working with our study investigators, academic partners, the patient community, and families to begin enrollment in the study promptly.

Sue Kahn, Executive Director of the National Tay-Sachs & Allied Diseases Association (NTSAD), added, This is a big step toward a potential therapy for the GM2 community. It has been a long journey since NTSAD started supporting this promising gene therapy research in 2006. We are thrilled that it is now entering the clinic, bringing tremendous hope to families and the entire NTSAD community.

Axovant aims to advance the program through strategic partnerships with leading research organizations. The Company recently announced a partnership with Viralgen, an AskBio subsidiary, to support AAV-based vector manufacturing of clinical trial material for the registrational study. Additionally, through an existing genetic testing collaboration with Invitae, ongoing partnership with GM2 gangliosidosis patient groups, and collaboration with leading academic researchers at the University of Massachusetts Medical School and Massachusetts General Hospital, Axovant expects to begin patient identification and site startup activities in preparation for dosing children in the planned clinical study.

AXO-AAV-GM2 is an investigational gene therapy for Tay-Sachs and Sandhoff diseases, which are rare, monogenic neurodegenerative lysosomal storage disorders caused by mutations in the genes that encode -Hexosaminidase A, HEXA and HEXB. Children affected by Tay-Sachs and Sandhoff diseases suffer from a progressively debilitating disease course and reduced life expectancy. AXO-AAV-GM2 delivers two vectors encoding the HEXA and HEXB genes directly to the central nervous system to produce a fully functional -Hexosaminidase A enzyme. In 2019, clinical evidence from two patients under an investigator-initiated study found that treatment with AXO-AAV-GM2 was generally well-tolerated and associated with improved bioactivity outcomes. In addition, the data demonstrated the attainment of normal neurodevelopmental milestones and improvement in myelination. AXO-AAV-GM2 has been granted Orphan Drug and Rare Pediatric Disease Designation by the FDA.

The study will enroll both infantile and juvenile subjects with GM2 gangliosidosis in the U.S. The two-part trial, sponsored by Axovant, will consist of (1) a dose ranging cohort evaluating the safe and efficacious dose of the gene therapy, followed by (2) an efficacy cohort, both of which form the basis of the registrational program. Terence R. Flotte, M.D., Professor of Pediatrics and Dean at the University of Massachusetts Medical School, will serve as principal investigator on the clinical trial.

About AXO-AAV-GM2

AXO-AAV-GM2 is an investigational gene therapy for GM2 gangliosidosis (also known as Tay-Sachs and Sandhoff diseases), a set of rare and fatal pediatric neurodegenerative genetic disorders caused by defects in theHEXA(leading to Tay-Sachs disease) orHEXB(leading to Sandhoff disease) genes that encode the two subunits of the -hexosaminidase A (HexA) enzyme. These genetic defects lead to progressive neurodegeneration and shortened life expectancy. AXO-AAV-GM2 aims to restore HexA function by introducing a functional copy of theHEXAandHEXBgenes via delivery of two co-administered AAVrh8 vectors.

About Axovant Gene Therapies

Axovant Gene Therapies is a clinical-stage gene therapy company focused on developing a pipeline of innovative product candidates for debilitating neurodegenerative diseases. Our current pipeline of gene therapy candidates target GM1 gangliosidosis, GM2 gangliosidosis (also known as Tay-Sachs disease and Sandhoff disease), and Parkinsons disease. Axovant is focused on accelerating product candidates into and through clinical trials with a team of experts in gene therapy development and through external partnerships with leading gene therapy organizations. For more information, visit http://www.axovant.com.

In 2018, Axovant licensed exclusive worldwide rights from the University of Massachusetts Medical School for the development and commercialization of gene therapy programs for GM1 gangliosidosis and GM2 gangliosidosis, including Tay-Sachs and Sandhoff diseases.

SOURCE: Axovant Gene Therapies

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Axovant Gene Therapies Announces FDA Clearance of IND for AXO-AAV-GM2 Gene Therapy in Tay-Sachs and Sandhoff Diseases | DNA RNA and Cells | News...

PhoreMost Limited, the UK-based biopharmaceutical company and Oxford Biomedica plc (LSE:OXB) (Oxford Biomedica), a gene and cell therapy group, today announced that they have entered into a discovery collaboration to develop next-generation CAR-T cell therapies. Financial details of the agreement are not disclosed.

PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER, to identify therapeutic candidates for Oxford Biomedicas LentiVector gene therapy delivery system. The program will initially focus on CAR-T therapy and aims to develop next-generation cell therapies with significantly improved efficacy and durability.

Dr Chris Torrance, CEO, PhoreMost, said: This collaboration with Oxford Biomedica, a global pioneer in cell and gene therapies, is further recognition of the power of SITESEEKER, offering an exciting opportunity to discover and accelerate the development of clinical stage products. The natural complementarity between SITESEEKER and LentiVector offers great promise for this and future collaborations between the two companies.

John Dawson, CEO of Oxford Biomedica, said: We are excited to apply this next-generation technology to our LentiVector platform. The collaboration has the potential to deliver more effective CAR-T therapies, and we look forward to working closely with the PhoreMost team.

SITESEEKER exploits protein shape diversity to find functionally active peptides linked to any chosen disease setting, significantly enhancing the power of phenotypic screening and translation into therapeutic modalities. Based on proprietary protein interference, or PROTEINi, technology, SITESEEKER is able to systematically probe the entire proteome in a live cell environment to identify and exploit novel drug targets.

Oxford Biomedica is a world-leading pioneer of cell and gene therapies. Its LentiVector platform enables the successful development of breakthrough gene and cell-based medicines, and through collaborations with pharmaceutical partners, has delivered the first FDA and EMA approved CAR-T cell therapy.

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PhoreMost and Oxford Biomedica Enter Gene Therapy Discovery Collaboration - Technology Networks