StemCell Therapy

Rare Disease Genetic Testing Market analysis report gives clear idea about the market potential for each geographical region based on the growth rate, macroeconomic parameters, consumer buying patterns, possible future trends, and market demand and supply scenarios. Competitive analysis is the major feature of any market research report, and hence Rare Disease Genetic Testing Market report covers many points including strategic profiling of key players in the market, analyse core competencies of key players, and draw a competitive landscape for the Rare Disease Genetic Testing industry. Different components which are in charge of market development, has been analyzed clearly in this report.

A reliable Rare Disease Genetic Testing Market report conducts the market overview with respect to general market conditions, market improvement, market scenarios, development, cost and profit of the specified market regions, position and comparative pricing between major players. The report involves the market drivers and limitations which are obtained from SWOT analysis. By working with a number of steps of collecting and analysing market data, this finest Rare Disease Genetic Testing Market research report is framed with the expert team. The large scale Rare Disease Genetic Testing Market report comprises of various segments linked to Rare Disease Genetic Testing industry and market with comprehensive research and analysis.

Rare disease genetic testing market is expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses the market to account to grow at a CAGR of 8.30% in the above-mentioned forecast period. The increase in the facilities for patients affected by rare diseases has been directly impacting the growth of rare disease genetic testing market.

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GlobalRare Disease Genetic TestingMarket Scope and Market Size

Rare disease genetic testing market is segmented on the basis of disease type, technology, specialty and end use. The growth amongst these segments will help you analyze meager growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

Rare Disease Genetic Testing Market Country Level Analysis:

The countries covered in the Rare Disease Genetic Testing Market report are U.S., Canada, Mexico in North America, Germany, Poland, Ireland, Italy, U.K., France, Spain, Netherland, Belgium, Switzerland, Turkey, Russia, Rest of Europe in Europe, Japan, China, India, South Korea, New Zealand, Vietnam, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in Asia-Pacific (APAC), Brazil, Argentina, Chile, Rest of South America as a part of South America, U.A.E, Saudi Arabia, Egypt, Kuwait, South Africa, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA).

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Leading Rare Disease Genetic Testing manufacturers/companies operating at both regional and global levels:

Quest Diagnostics, Inc., Centogene N.V., Eurofins Scientific, Strand Life Sciences, Ambry Genetics, PerkinElmer, Inc., Macrogen, Inc., Baylor Genetics, Color, Health Network Laboratories, L.P., Preventiongenetics, Progenity, Inc., Invitae Corporation, 3billion, Inc., Arup Laboratories, Coopersurgical, Inc., Fulgent Genetics, Myriad Genetics, Inc., Laboratory Corporation Of America Holdings and Opko Health, Inc., among other domestic and global players.

Key points of the report

Reasons for purchasing this Report

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Table Of Contents: Rare Disease Genetic Testing MarketPart 01: Executive Summary

Part 02: Scope Of The Report

Part 03: Research Methodology

Part 04: Market Landscape

Part 05: Pipeline Analysis

Part 06: Market Sizing

Part 07: Five Forces Analysis

Part 08: Market Segmentation

Part 09: Customer Landscape

Part 10: Regional Landscape

Part 11: Decision Framework

Part 12: Drivers And Challenges

Part 13: Market Trends

Part 14: Vendor Landscape

Part 15: Vendor Analysis

Part 16: Appendix

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Originally posted here:
Rare Disease Genetic Testing Market To Account To Grow At A CAGR Of 8.30% In The Forecast Period Of 2020 To 2027 | Top Companies- Quest Diagnostics,...

The information below has been supplied by dairy marketers and other industry organizations. It has not been edited, verified or endorsed by Hoards Dairyman.

New Generation Genetics is excited to welcome Lauren Hendel as U.S. Sales and Progeny Specialist effective December 1, 2020.

Lauren brings diverse experience and knowledge of the dairy genetics industry. This includes experience in marketing, daughter progeny identification and photography, customer service, and A.I. bull care, collection, and semen processing.Most recently, she worked as a Genetic Consultant in southern Wisconsin.In this role she helped customers reach their genetic goals through sire selection and mating.

Laurens passion for Brown Swiss began at a young age. Growing up, she was actively involved on her familys 400-cow dairy, near Caledonia, MN. Hendel Farms has been home to registered Brown Swiss since 1922.

Lauren has an ideal skill set for this position and will be a very valuable asset to NGG going forward, stated CEO Dan Gilbert.We are confident Breeders in the Midwest and West will benefit and appreciate working with her.

Lauren is a graduate of the University of Minnesota Twin Cities with a Bachelor of Animal Science and minor in Agricultural and Food Business Management. While there she was active in the Gopher Dairy Club, and a member of the dairy judging and dairy challenge teams.

Lauren will be working out of the home office in Fort Atkinson, WI and will be covering semen sales in the Midwest & Western regions of the USA. Lauren will also coordinate progeny photography, assist with NGG's social media platform, press releases, advertising, web site maintenanceand other office responsibilities.

Continue reading here:
New Generation Genetics is excited to welcome Lauren Hendel as US Sales and Progeny Specialist effective December 1, 2020. - Hoard's Dairyman

Researchers inserted genes into mouse eye cells to protect and restore the optic nerve (red fibers in microscope image of healthy mouse retina, above).

By Kelly ServickDec. 2, 2020 , 5:30 PM

Do old and damaged cells remember what it was like to be young? Thats the suggestion of new study, in which scientists reprogrammed neurons in mouse eyes to make them more resistant to damage and able to regrow after injurylike the cells of younger mice. The study suggests that hallmarks of aging, and possibly the keys to reversing it, lie in the epigenome, the proteins and other compounds that decorate DNA and influence what genes are turned on or off.

The idea that aging cells hold a memory of their young epigenome is very provocative, says Maximina Yun, a regenerative biologist at the Dresden University of Technology who was not involved in the work. The new study supports that [idea], but by no means proves it, she adds. If researchers can replicate these results in other animals and explain their mechanism, she says, the work could lead to treatments in humans for age-related disease in the eye and beyond.

Epigenetic factors influence our metabolism, our susceptibility to various diseases, and even the way emotional trauma is passed through generations. Molecular biologist David Sinclair of Harvard Medical School, who has long been on the hunt for antiaging strategies, has also looked for signs of aging in the epigenome.

The big question was, is there a reset button? he says. Would cells know how to become younger and healthier?

In the new study, Sinclair and his collaborators aimed to rejuvenate cells by inserting genes that encode reprogramming factors,which regulate gene expressionthe reading of DNA to make proteins. The team chose three of the four factors scientists have used for more than 10 years to turn adult cells into induced pluripotent stem cells, which resemble the cells of an early embryo. (Exposing animals to all four factors can cause tumors.)

The team focused specifically on neurons at the back of the eye called retinal ganglion cells. These cells relay information from light-sensitive photoreceptors to the brain using long tendrillike structures called axons, which make up the optic nerve. Theres a stark divide between youth and age in these cells: An embryonic or newborn mouse can regenerate the optic nerve if it gets severed, but that ability vanishes with time.

To test whether their treatment could bring back some of that resilience, Sinclair and colleagues crushed the optic nerves of mice using forceps and injected a harmless virus into the eye carrying the genes for the three reprogramming factors. The injection prevented some damaged retinal ganglion cells from dying and even prompted some to grow new axons reaching back to the brain, the team reports today in Nature.

When the researchers looked at methylation patternsthe DNA location of chemical tags called methyl groups that regulate gene expressionthey found that changes caused by the injury resembled those in aging mouse cells. In certain parts of the genome, the treatment reversed those changes. The researchers also found that the benefits of the introduced genes depended on cells ability to alter their methylation patterns: Mice lacking certain enzymes necessary to remove methyl groups from DNA saw no benefit to the treatment.

Thats really something special, says Leonard Levin, a visual neuroscientist at McGill University. The experiments suggest how the famous and well-studied reprogramming factors restore cells. But big questions remain, he says: How do these factors cause methyl groups to be added or removed? How does that process help retinal ganglion cells?

Sinclairs team also tested the approach in mice with a condition meant to mimic glaucoma, a leading cause of age-related blindness in humans. In glaucoma, the optic nerve gets damaged, often by a buildup of pressure in the eye. Sinclair and his colleagues injected tiny beads into the animals eyes that prevented normal drainage and increased pressure, which damaged retinal ganglion cells.

Four weeks later, the animals visual acuity had declined by about 25%, as measured by a vision test in which mice move their heads to track the movement of vertical bars displayed on computer monitors. But after the genetic treatment, the animals gained back roughly half of their lost acuitythe first demonstration of restored vision in mice after this glaucomalike injury.

Still, the improvement in acuity was small, Levin notes. And, he says, the treated mice were in a relatively early stage of damage, not the state of near or total blindness that people experience when glaucoma goes untreated for years. So its too early to say whether this approach could benefit people who have lost much of their vision. Levin adds that there are already very good treatments for early-stage glaucoma to prevent vision loss with medicated eye drops or surgery to lower eye pressure.

In a final set of experiments, Sinclair and colleagues injected the reprogramming-factor genes into the eyes of 1-year-old healthy mice, roughly the mouse equivalent of middle-age. By this stage, the animals had visual acuity scores about 15% lower than their 5-month-old counterparts. Four weeks after treatment, older mice had similar acuity scores to younger ones. In their cells, the researchers saw patterns of DNA methylation and gene expression resembling those of younger animals.

In the three sets of experiments, Sinclair says, the cells seemed to respond to the reprogramming factors by fine-tuning their gene expression to match a youthful state. He sees that behavior as a hint that cells keep a record of their epigenetic past, even though its not clear how that record is stored. A company Sinclair cofounded, Life Biosciences, is developing treatments for diseases associated with aging, including glaucoma, and he says hes now planning to test the safety of this gene therapy approach in larger animals.

Yun says that as a strategy for reversing aging or treating disease, resetting the epigenome is a very difficult one. Reprogramming cells to an earlier state carries a risk of prompting uncontrolled growth and cancer.Future studies should test how the three factors affect other types of cells and tissues and confirm that reprogrammed cells maintain their youthful state long-term, she says. There are a lot of roads to be traveled.

Originally posted here:
Researchers restore lost sight in mice, offering clues to reversing aging - Science Magazine

Aging has implications for a wide range of diseases. Researchers have been looking for ways to halt the aging process for millennia, but such methods remain elusive. Scientists at Harvard Medical School have now offered a glimmer of hope that the aging clock in the eye could be reversedat least in animals.

By reprogramming the expression of three genes, the Harvard team successfully triggered mature nerve cells in mice eyes to adopt a youthful state. The method reversed glaucoma in the mice and reversed age-related vision loss in elderly mice, according to results published in Nature.

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If further studies prove out the concept, they could pave the way for therapies that employ the same approach to repair damagein other organs and possibly treat age-related diseases in humans, the team said.

The researchers focused on the Yamanaka factors, which are four transcription factorsOct4, Sox2, Klf4 and c-Myc. In a Nobel Prize-winning discovery, Shinya Yamanaka found that the factors can change the epigenomehow genes are turned on or offand can thereby transform mature cellsback to a stem cell-like state. It has been hypothesized that changes to the epigenome drive cell aging, especially a process called DNA methylation, by which methyl groups are tagged onto DNA.

Past researches have tried to use the four Yamanaka factorsto turn back the age clock in living animals, but doing so caused cells to adopt unwanted new identities and induced tumor growth.

RELATED:Restoring eyesight with genetically engineered stem cells

To test whether the approach works in living animals, the scientists used adeno-associated virus to deliver the three genes into the retina of mice with optic nerve injuries. The treatment led to a two-fold increase in the number of retinal ganglion cells, which are neurons responsible for receiving and transmitting visual information. Further analysis showed that the injury accelerated DNA methylation age, while the gene cocktail counteracted that effect.

Next the scientists tested whether the gene therapy could also work in disease settings. In a mouse model of induced glaucomawhich is a leading cause of age-related blindness in peoplethe treatment increased nerve cell electrical activity and the animals visual acuity.

But can the therapy also restore vision loss caused by natural aging? In elderly, 12-month-old mice, the gene therapy also restored ganglion cells electrical activity as well as visual acuity, the team reported.

By comparing cells from the treated micewith retinal ganglion cells from young, 5-month-old mice, the researchers found that mRNA levels of 464 genes were altered during aging, and the gene therapy reversed 90% of those changes. The scientists also noticed reversed patterns of DNA methylation, which suggests that DNA methylation is not just the marker but rather the driver behind aging.

What this tells us is the clock doesn't just represent timeit is time. If you wind the hands of the clock back, time also goes backward, the studys senior author, David Sinclair, explained in a statement.

The study marks the first time that glaucoma-induced vision loss was reversednot just slowedin living animals, according to the team.

RELATED:Reprogrammed skin cells restore sight in mouse models of retinal disease

Other researchers are also studying regenerative approaches to treating eye diseases. A research group at the Centre for Genomic Regulation in Barcelona just showed that by modifying mesenchymal stem cells to express chemokine receptors Ccr5 and Cxcr6, retinal tissue could be saved from degeneration.

The idea of reversing age-related decline in humans by epigenetic reprogramming with a gene therapy is exciting, Sinclair said. The Harvard researchers intend to do more animal work that could allow them to start clinical trials in people with glaucoma in about two years.

Our study demonstrates that it's possible to safely reverse the age of complex tissues such as the retina and restore its youthful biological function, Sinclair said. If affirmed through further studies, these findings could be transformative for the care of age-related vision diseases like glaucoma and to the fields of biology and medical therapeutics for disease at large.

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Reversing vision loss by turning back the aging clock - FierceBiotech

The study of 1,000 Canadians requiring vision correction, conducted by research firm Leger, showed that 34 per cent of Canadians requiring vision correction say their eyes feel more tired during the pandemic than they did before, which is a possible sign of digital eyestrain, a condition caused by spending too much time in front of screens. A study found the effects of long-term computer use on the eyes suggest that digital eyestrain is a form of evaporative dry eye. As a result, tears evaporate on the surface of the eye and can cause them to feel dry, tired or irritated. Despite this:

"While it's tempting to turn to streaming services and e-books for entertainment after long days of working and learning on screens, I'm seeing patients in my clinic who are suffering from sore, tired eyes as a result, which could be a sign of dry eye caused by digital eyestrain," says Dr. Shawn Moore, optometrist at Orillia Optometry. "Conditions like dry eye can also present as blurry vision, so if you're experiencing changes in your eyesight, patients still need to prioritize seeing an optometrist at this time to re-assess their vision care needs. Your eye doctor might recommend using an eye drop with lipids, like SYSTANE COMPLETE, or switching to a daily disposable contact lens featuring water gradient technology, like DAILIES TOTAL1."

In addition to dry eye and worsening vision, the survey showed that Canadians are frustrated with the inconvenience and nuisance of foggy glasses caused by wearing a mask and glasses together while running errands. Three-quarters of Canadians who wear glasses say their glasses fog up when wearing masks; 35 per cent say they adjust their glasses more when wearing them with masks; and more than half of Canadians (51 per cent) requiring vision correction wear contact lenses when going outside.

Experiencing changes with your vision during COVID-19? The following steps could help:

For more information, talk to your eye care professional to learn more about DAILIES TOTAL1 or SYSTANE COMPLETE.

Study Methodology An online survey of 1,000 Canadians who wear corrective eye wear was completed between September 22 and September 27, 2020, using Leger's online panel. For comparative purposes, a probability sample of 1000 respondents would have a margin of error of 3.1%, 19 times out of 20.

About Alcon Alcon helps people see brilliantly. As the global leader in eye care with a heritage spanning more than seven decades, Alcon offers the broadest portfolio of products to enhance sight and improve people's lives. Alcon's Surgical and Vision Care products touch the lives of more than 260 million people in over 140 countries each year living with conditions like cataracts, glaucoma, retinal diseases and refractive errors. More than 20,000 Alcon associates are enhancing the quality of life through innovative products, partnerships with eye care professionals and programs that advance access to quality eye care. For more information, visit http://www.alcon.ca.

2020 Alcon Inc. 11/20 CA-DT1-2000097

SOURCE Alcon Canada

For further information: Viktoria Kiely, Cohn & Wolfe, [emailprotected], 647.259.3273

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Many Canadians believe COVID lifestyle changes are affecting their eyes - Canada NewsWire

Since my early 20s, Ive been making spectacles of myself in a manner of speaking. During my boyhood years, my right eye had occasional encounters with things like tennis balls and a toy pistol, so my distance vision needed correction. Ive worn eyeglasses ever since. However, being nearsighted, I dont need them for things up close.

My wife is different. Thanks to recent cataract surgery, she now has near-perfect farsighted vision. Its seeing things up close that poses problems. Combined, we can boast 20:20 vision both far and near, even though lots of things havent looked all that good in 2020.

If you were to choose, which would you prefer? Flawless farsighted vision, or excellent close-up vision? In terms of physical eyesight, a good argument could be made for either. It depends on what youre wanting to do.

But spiritually speaking, Im convinced being farsighted has to be the preferred choice. The Bible affirms this over and over. Its at the heart of the Christian faith being willing to trust in things we can only see from afar, despite disheartening circumstances that might surround us.

The Scriptures abound with numerous examples of what we might call spiritual farsightedness. Jesus, speaking to the doubting disciple Thomas after he insisted on seeing visible proof of His resurrection, said, Because you have seen Me, you have believed; blessed are those who have not seen and yet have believed (John 20:29).

After suffering a series of personal losses, including his children, and wracked by painful sores over his entire body, Job declared, I know that my Redeemer lives, and that in the end he will stand upon the earth. I myself will see him with my own eyes I, and not another. How my heart yearns within me! (Job 19:26-27).

Here are some other passages that underscore this emphasis on the value of spiritual far-sight:

So we fix our eyes not on what is seen, but on what is unseen, since what is seen is temporary, but what is unseen is eternal (2 Corinthians 4:18).

For we walk by faith, not by sight (2 Corinthians 5:7).

While we wait for the blessed hope the glorious appearing of our great God and Savior, Jesus Christ (Titus 2:13).

Dear friends, now we are children of God, and what we will be has not yet been made known. But we know that when he appears, we shall be like him, for we shall see him as he is (1 John 3:2).

The 11th chapter of the book of Hebrews speaks extensively about the need for spiritual farsightedness, even when the way ahead seems dark or obscured:

Now faith is the substance of things hoped for, the evidence of things not seen (Hebrews 11:1).

By faith Noah, when warned about things not yet seen, in holy fear built an ark to save his family (Hebrews 11:7).

By faith Abraham, when called to go to a place he would later receive as an inheritance, obeyed and went, even though he did not know where he was going (Hebrew 11:8).

All these people were still living by faith when they died. They did not receive the things promised; they only saw them and welcomed them from a distance (Hebrews 11:13).

After citing other glowing examples of unwavering, unconquerable faith, the chapter reaffirms, These were all commended for their faith, yet none of them received what had been promised. God had planned something better for us so that only together with us would they be made perfect (Hebrews 11:39-40).

We find ourselves in the closing days of an unforgettable year many of us wish we could forget. What weve been seeing, up close and personal, often hasnt passed the eye test. This is all the more reason for practicing, as did the biblical patriarchs, a faith that looks not down but ahead toward a not yet seen, but promised future of joy and peace. Anticipating the time when well be experiencing the words of the old hymn, It Is Well With My Soul: when the faith shall be sight.

* * *

Robert J. Tamasy is a veteran journalist, former newspaper editor and magazine editor. Bob has written, co-authored and edited more than 15 books. These include the newly published, Marketplace Ambassadors; Business At Its Best: Timeless Wisdom from Proverbs for Todays Workplace; Tufting Legacies, The Heart of Mentoring, and Pursuing Life With a Shepherds Heart. A weekly business meditation he edits, Monday Manna, is translated into more than 20 languages and sent via email around the world by CBMC International. The address for his blog is http://www.bobtamasy.blogspot.com. His email address is btamasy@comcast.net.

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Bob Tamasy: Overcoming The Obstacle Of Near-Sightedness - The Chattanoogan

JOCKEY Danny Cook is fighting to save his eyesight after suffering horrific facial injuries when he was kicked by a horse.

The Jumps star needed 50 stitches to his face and suffered a broken nose and fractured eye socket following the terrifying incident last month.

2

Cook, 37, was rushed to hospital and treated for head wounds after being kicked at Market Rasen in October.

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Incredibly, he made his racing comeback on November 21 but pulled out of last Sunday's races at Carlisle after falling off Definitly Red at Newcastle on Saturday.

Cook said he chose not to ride because he cannot see properly in one eye - and could be forced to retire if it does not improve.

He told the Yorkshire Post: "I'm going to take time out to get myself sorted.

"If they operate, there's an 80 per cent chance my sight will be even worse so I need to weigh up all the options.

"Hopefully I will know more in the next week. If it doesn't get better I will not return."

Cook - who has total career earnings on the track of just under 3m - is desperate to return to racing and had been looking forward to riding again over the busy Christmas schedule.

But that is now all on hold as he waits to find out if his vision will ever return to normal.

2

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He told the Racing Post: "Ive been having trouble with my eyesight since Ive been back riding. Im going to see the specialist and try to get something sorted.

"This is the time of year when you want to race as much as you can. All the good horses are out.

"It's frustrating being off but it's a necessity because I'm not able to ride to my full capacity with only one eye."

He added: "Mentally I am good to go and I am confident and strong.

"But the vision is very much impaired when I go into a jump - it's not helping.

"I have got to look after myself. If I can't ride at my best, I must get myself sorted.

"Whatever happens I have had a good innings and hopefully it is not the end."

Cook's admission he may be forced to retire comes after fellow jockey Harry Cobden was lucky to avoid serious injury over the weekend.

He fell underneath charging horses at Newbury but was shown walking to the on-course ambulance.

And just last week Flat rider Eoin Walsh was rushed to hospital with a broken back following a fall at Chelmsford.

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Jockey Danny Cook fighting to save eyesight and career after needing 50 stitches to his face when kicked by - The Sun

Doctors point to a rising incidence in retinal vascular occlusions this year; patients also report sudden onset of double vision

Ophthalmologists have been seeing more patients with complaints of eyesight loss this year, and doctors suspect COVID-19 may have a role to play.

Doctors are relying on literature from other countries to confirm their diagnosis and suspicions. The retina is a thin layer of tissue at the back of the inside of the eye which receives light from the lens and sends it as neural signals to the brain through the optic nerve. When blood supply to the eye is hindered, the retina cannot function.

Mohan Rajan of Rajan Eye Care Hospital said he was seeing patients with loss of vision or double vision. Occlusions of the retinal blood vessels, following COVID-19 infection, have been reported. This is akin to a heart attack to a cardiologist and a stroke to a neurologist, he said.

Arteries and veins of the retina are exposed to the same pathological processes, and this affects ocular circulation as well. Patients have also reported a sudden onset of double vision and drooping of eyelids following COVID-19, due to paralysis of the nerves of the eye, he said.

Priya Sivakumar, neuro-ophthalmologist, Aravind Eye Care Hospital, Puducherry, said there had been an increase in the number of patients coming with loss of vision. Since initially testing for COVID-19 was not easily accessible, these patients were treated with steriods.

We could not test the patients for COVID-19 but suspected it as a cause because of the change in trend between last year and the current. Last year, we treated 20 patients in whom both eyes were affected.This year, from March to October, we have seen around 40 patients, she said. In her experience, the patients recovered when treated early.

Rajiv Raman, senior retina consultant, department of vitreo-retina, Sankara Nethralaya, said people recovering from COVID-19 had a tendency to form clots, which were treated using blood thinners. Occlusion (clot) in the blood vessel can occur in arteries and veins. If it occurs in an artery in the eye, the first six hours are the golden hours within which vision can be restored in some cases. In case of a vein occlusion, vision can be improved, to an extent, with treatment, but it might not return to normal, he said.

Dr. Rajiv said the hospital had not analysed its data. But in general, we are seeing more retinal vascular occlusions now. The occlusions could also be due to cardiovascular disease, diabetes or hypertension. Sankara Nethralaya, being a tertiary care centre, has been seeing many vivid recovered patients from across the country now, he added.

There seems to be more incidence of retinal vascular occlusions. There is emerging literature evidence supporting this fact.

Read the original:
COVID-19 could be reason for increase in patients with eyesight loss, say doctors - The Hindu

Dry eye is a common condition during the winter season

Dry eye is a condition in which your eyes are not able to produce enough tears and fails to provide adequate lubrication to the eyes. This condition can cause symptoms like itching, redness, blurred vision, sensitivity to light, gritty sensation and discomfort in completing certain tasks. Just like your skin and other body parts, the winter season affects your eyes too. It is not a surprise that your eyes are drier during the winter season. There are several reasons behind it. Dry eyes also become quite common with the drop in temperature. We spoke to Dr. Tushar Grover, Medical Director at Vision Eye Centre, New Delhi to understand what exactly leads to an increase in the incidents of dry eye cases and how to prevent this condition.

Dr. Grover explains, "Although there are certain underlying systemic conditions such as Rheumatoid arthritis, Sjogren's syndrome or vitamin A deficiency that can lead to dry eyes in a small subset of individuals, some of the most common factors which cause dryness in otherwise healthy eyes include cold temperature, low humidity and windy weather."

Also read:Exercise Your Eyes! Reduce Eye Strain With These Expert Recommended Eye Exercises

1. One should keep eyes constantly moisturised using eye drops, artificial tears or eye ointment. You should check with your doctor once to choose the best option for you.

Use eye drops can help prevent dry eyes during the winter seasonPhoto Credit: iStock

2. Shield your eyes using UV-protected wraparound glasses or a visor hat whenever you are outdoors.

3. Keep the indoor room temperature reasonably warm and not excessively hot when using heating systems such as heaters and blowers. Also, ensure that your face doesn't directly get in the way of the heat from the appliance.

Also read:5 Nutrients You Should Not Miss To Maintain Healthy Eyesight

4. Use a humidifier indoors to retain the moisture in the room. It will also help you prevent dry skin.

5. Apply warm compresses in case of extreme discomfort or irritation in the eye because of dryness. Warm compresses also help open up the clogged Meibomian glands responsible for secreting oil or meibum which prevents evaporative dry eye.

Also read: All About Vitamin A

6. Don't ignore nutritional requirements such as vitamin A and omega-3 fatty acids and consume food items that are rich in those nutrients.

Vitamin A is responsible for ensuring healthy eyesightPhoto Credit: iStock

7. Avoid continuous use of screen-based gadgets. At the same time, try to blink more frequently.

8. Keep your body hydrated all the time by regularly taking water and other fluids. A hydrated body would also keep eyes moisturized enough.

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

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Dry Eyes In Winter: Follow These Expert Recommended Tips To Prevent This Condition - NDTV

A DRIVER failed an eyesight test after his car hit a pedestrian.

The DVLA revoked his licence less than anhour after the crash in Chichester this morning.

Sussex Roads Police attended the scene at about 11.30am and confirmed that there had been no serious injuries as a result of the collision.

A spokesman for the force said: "We are at the scene of a road traffic collisionin Chichester where a car hit a pedestrian.

"Thankfully, this was low speed and injuries are not serious.

"We conducted an eyesight test with the driver, which he failed.

"The Driver and Vehicle Licensing Agency (DVLA) have already revoked his licence, less than onehour after the road traffic collision."

Sussex Roads Police have been contacted for further information.

The DVLA has a list of "driving eyesight rules" on its website.

These state: "You must wear glasses or contact lenses every time you drive if you need them to meet the standards of vision for driving.

"You must tellDVLAif youve got any problem with your eyesight that affects both of your eyes, or the remaining eye if you only have one eye.

"This doesnt include being short or long sighted, or colour blind.

"You also dont need to say if youve had surgery to correct short sightedness and can meet the eyesight standards.

"You must be able to read (with glasses or contact lenses, if necessary) a car number plate made afterSeptember 1 2001 from 20 metres."

Drivers are also recquired tohave an "adequate field of vision". This can be assessed by opticians, who are also able to provide more information on the standard drivers need to meet.

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Driver fails eyesight test after hitting pedestrian with car - The Argus

4D Molecular Therapeutics raised $75 million in June to get several gene therapy programs into and through the clinic. Now, its adding a trio of executives to spearhead its work in heart, eye and lung diseases as it looks to shepherd treatments in those focus areas forward.

Robert Fishman, M.D. becomes 4Ds chief medical officer and therapeutic area head for pulmonology. He joins from Xoc Pharmaceuticals, where as chief medical officer he led phase 1 development for programs in Parkinsons disease and migraine. Before that, he headed clinical development at InterMune, overseeing the pivotal trial of Esbriet, an idiopathic pulmonary fibrosis drug now marketed by Roche.

Accelerate Biologics, Gene and Cell Therapy Product Development partnering with GenScript ProBio

GenScript ProBio is the bio-pharmaceutical CDMO segment of the worlds leading biotech company GenScript, proactively providing end-to-end service from drug discovery to commercialization with professional solutions and efficient processes to accelerate drug development for customers.

RELATED: Restoring eyesight with genetically engineered stem cells

Raphael Schiffmann, M.D., signs on as senior vice president and therapeutic area head for 4Ds cardiology stable. He was previously director of the Institute of Metabolic Disease at the Baylor Research Institute and the lead investigator of the developmental and metabolic neurology branch at the NIHs National Institute of Neurological Disorders and Stroke.

Robert Kim, M.D., joins 4D as a senior vice president and clinical therapeutic area head of ophthalmology. Hes held multiple chief medical officer roles at ViewPoint Therapeutics, Apellis Pharma and Vision Medicines, and earlier in his career worked in ophthalmology at GlaxoSmithKline, Genentech and Novartis.

The three executives arrive six months after 4D topped up its coffers with a $75 million series C round. The capital, which came two years after a $90 million B round, was earmarked to push three programs into the clinic, including two that are partnered with Roche.

Those programs include 4D-310, a treatment for Fabry disease in which patients cells accumulate a type of fat called globotriaosylceramide, and 4D-125, a treatment for the eye disease X-linked retinitis pigmentosa. Roche has the exclusive right to develop and commercialize the latter. Roche has licensed the third prospect, 4D-110, a treatment for a type of vision loss called choroideremia.

RELATED: 4D raises $90M to move gene therapies into clinical testing with AstraZeneca and Roche

The funds will also bankroll the development of 4Ds preclinical pipeline, including IND-enabling studies for 4D-710, a program in cystic fibrosis, and other candidates for neuromuscular diseases and ophthalmology.

With the addition of Robert Fishman, Raphael Schiffmann and Robert Kim to our clinical R&D leadership team, 4DMT gains not only extensive experience in clinical development and translational medicine, but also unique and specific experience within each of the initial 4DMT therapeutic areas," said 4D CEO David Kim, M.D., in a statement.

More here:
4D hires a trio of area heads as it ramps up its gene therapy pipeline - FierceBiotech

A mum was left partially blinded after she was crushed in front of her children when the skippers of two powerboats bungled a stunt turn and rammed into each other.

Jane Francis, 45, suffered catastrophic life-changing injuries that includes permanent damage to her eyesight leaving her with just 60 per cent vision.

She also sustained other serious injuries including several broken bones and a punctured lung during the accident on the Isle of May off Scotland, the Daily Record reports.

On Wednesday, Isle of May Boat Trips Ltd was fined at Dundee Sheriff Court after it admitted responsibility for the crash which happened when two skippers were carrying out a "synchronised power turn" move in July 2016.

Sheriff Alastair Carmichael said: "Jane Francis was seriously injured. Her injuries included several broken bones and a punctured lung.

"She sustained damage to her diaphragm that required surgery in 2018. The crushing injuries that she sustained caused severe damage to her eyesight which has been permanently impaired.

"She has post traumatic stress disorder as a result of the collision. The final figure is not, I stress, in any way intended to be a financial value for Jane Francis' injuries or impairment.

"There was no clear procedure in place for the skippers to follow when the synchronised power turn started to go wrong," the sheriff said.

He said the company had failed to make a suitable risk assessment, failed to provide passengers with a suitable pre-departure briefing, and failed to ensure the power turn had been properly planned.

Mrs Francis said: "My eyes suffered damage during a thoracic crush injury and I have what is called Purtscher's Retinopathy.

"This causes sight loss and damage to areas of the retina which see colour and surface detail. I have what I approximate to be about 40 per cent sight loss.

"I have no sight in the central vision of my right eye. The remaining areas across both eyes have patches of missing sight."

The court heard how she suffered catastrophic injuries during the crash when the two skippers collided while they were showing off to passengers on a cruise ship.

Mrs Francis was injured when the two Osprey rigid inflatable 12-person vessels ran into each other during a pleasure trip to view the wildlife on the Isle of May.

The court was told that the power turn was carried out to give unsuspecting passengers an "exhilarating" experience during the trip to view the birds on the island.

The court heard that the one of the skippers told passengers the manoeuvre would make people on the nearby May Princess wish they had come on the powerboat trip instead of the cruise ship.

However, when the boats completed their arc at speed they came back together closer than planned and one of the skippers swerved in the wrong direction.

Anstruther lifeboat coxswain Roy Giles, a director of the company, correctly turned his vessel in a starboard direction in accordance with maritime rules.

But Simon Chapman turned his board in a port direction and ran into the company's sister vessel, injuring Mrs Francis, who was on a day out with her husband.

The Cellardyke-based company admitted being in breach of the Merchant Shipping Act 1995 and being responsible for Mrs Francis's injury and impairment.

The company admitted that on 19 July 2016 it failed to take all reasonable steps to ensure the trip was carried out safely and failed to properly plan the power turn.

Fiscal depute Gavin Callaghan said Mrs Francis suffered several broken ribs, broke both clavicles and tore her shoulder, as well as suffering a retinopathy.

"As a result vision in both her eyes has been affected. She has a large black spot in her field of vision in her right eye and can only see light and dark in her left eye.

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"She is able to read with difficulty, a few letters at a time. She describes herself as having severe visual impairment. Diaphragm damage has affected her liver.

"She suffers PTSD and panic attacks. She is left with a fear of being somewhere that emergency vehicles find hard to access. Her memory and concentration have been affected."

Mr Callaghan said the power turn had not been explained to the passengers on the two Osprey boats, so they could not make an informed choice about whether to go on the trip.

"Simon Chapman said they would undertake manoeuvres which would make passengers on the May Princess wish they had come on this trip instead."

The prosecutor told the court that the boats should not have come within 20 metres of each other and would not have collided but for Mr Chapman's error.

Counsel for the company, Gavin Anderson, said the company no longer allowed skippers to do power turns and had taken other steps to improve on-board safety.

He said: "We wish to express the company's profound regret at causing a risk of injury and actual injury to Mrs Francis.

"The time taken from the beginning of the manoeuvre to the collision would have been no more than 15 seconds. Both skippers knew not to pass closer than 20 metres from another vessel.

"The company recognise the matter is a serious one. The company fell short of the appropriate standard. The manoeuvre which gave rise to the accident is simply not done at all now."

The company has been allowed to pay the fine at 3,000 per year.

View original post here:
Mum blinded after being crushed in front of her kids in boat trip 'stunt' horror - Mirror Online

SportOther SportDANNY Cook hopes eye surgeons can save his career after being forced to give up race-riding for the time being.

Sunday, 29th November 2020, 2:01 pm

He made the decision immediately after Definitly Red, a horse integral to his career, fell in Newcastles Rehearsal Chase. He cited medical reasons for giving up two rides at Carlisle on Sunday.

Cook had returned to the saddle on November 21 just weeks after suffering a fractured eye socket in a horror fall. He required 60 stitches to facial injuries following a fall at Market Rasen in which he was kicked in the face by a pursuing horse.

But the jockey, who has built a strong association with Yorkshire trainers Sue Smith and Brian Ellison, has conceded that he is currently unable to do justice to his rides because of impaired vision during races.

Im going to take time out to get myself sorted its just one of those things, he told The Yorkshire Post.

If they operate, theres an 80 per cent chance my sight will be even worse so I need to weigh up all the options.

Hopefully, I will know more in the next week. If it doesnt get better, I will not return.

Cook denied widespread weighing room speculation that he had already chosen to retire. People are going to say what they are going to say, he went on.

Mentally, I am good to go and I am confident and strong. But the vision is very much impaired when I go into a jump its not helping.

I have got to look after myself. If I cant ride at my best, I must get myself sorted. Whatever happens, I have had a good innings and hopefully it is not the end.

Time will tell. I have just got to take time to get it right because I dont feel I am riding to the best of my ability as things stand.

Ellison said that the jockey had told him that he was finished after the ride on Definitly Red, a former winner of Wetherbys Charlie Hall Chase, at Newcastle.

The Malton trainer says the horse appears sound after a fall which saw the multiple Grade Two winner, and former Cheltenham Gold Cup contender, slither along the turf. He says Definitly Red could reappear at Christmas.

The Rehearsal Chase was ultimately won by the resurgent Yorkhill for Sandy Thomson and former Grand National-winning jockey Ryan Mania, who was recording his most significant win since he made his own comeback from retirement just over a year ago.

A multiple Grade One winner with Willie Mullins, Yorkhill had badly lost his way in the last two seasons after successive wins at the Cheltenham Festival seemingly had left him destined for greatness.

Golfing star Lee Westwood took over ownership with friend David Armstrong, from their mutual acquaintance Sir Graham Wylie, and sent him to be trained in the Scottish Borders by Thomson.

I think he just needed the personal touch theyve given him a bit of time to nurture him back to where he was, eulogised an emotional Westwood. I was at Cheltenham the day he beat Yanworth, and I got a real feel he was back to that sort of form.

His ears were pricked, he loved his jumping, and when they came at him he went away again he was even racing the loose horse at the end. I was in tears.

Champion Hurdle heroine Epatante confirmed her class by landing the Grade One Fighting Fifth Hurdle in scintillating style Micky Hammonds Cornerstone Lad, the 2019 winner, was a non-runner because of the quick ground.

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Jockey Danny Cook fighting to save eyesight and career - Yorkshire Post

Exercise brings countless benefits to the mind and body; namely burning fat and fortifying mental health. There is no shortage of studies that demonstrate its impact on longevity but knowing what to do and how much to do can seem bamboozling, particularly if you are starting out. Fortunately, you can add years to your lifespan without the need to invest in high-tech equipment or engaging in high-intensity exercise.

Research published in Mayo Clinic Proceedings extolls the benefits of brisk walking, suggesting that the straight-forward exercise can boost your longevity by years.

What's more, the finding was consistent across all body profiles.

The researchers monitored the walking habits and deaths of nearly 475,000 people, most of whom were in their 50s at the start of the study, and found that people who have a quicker walking pace lived longer than those who walked more slowly.

Brisk walking was defined by researchers as walking at least three miles per hour, or 100 steps a minute.

READ MORE:How to live longer: Cinnamon lowers risk of Alzheimers & heart disease to boost longevity

However, walking pace was self-reported by participants, who were asked to indicate whether they walked at a slow pace, steady/average pace, or brisk pace.

Participants with brisk walking paces had longer life expectancies across all categories of body mass index (BMI).

The BMI is a measure that uses your height and weight to work out if your weight is healthy.

"The survival is the same for fast walkers for a wide range of body mass index, from 20 to 40, Dr Francesco Zaccardi, a clinical epidemiologist at the University of Leicester in the United Kingdom and the studys lead researcher, told Healthline.

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"This result indicates that physical function is a stronger determinant of longevity than body mass index, and also people with high body mass index but with good fitness may survive longer, he said.

Conversely, participants with slower walking paces had shorter life expectancies across all categories of BMI.

Researchers reported that women who walked more quickly had a life span of about 87 years compared to 72 years for women who walked slowly.

Men who walked quickly had a life span of about 86 years compared to 65 years for men who walked more slowly.

That works out as a 15-year average difference for women and a 20-year average difference for men.

Exercise is integral to longevity because it provides a bulwark against obesity, which can usher in life-threatening diseases and conditions.

These include:

Obesity can also undermine your quality of life and lead to psychological problems, such as depression and low self-esteem.

In addition to exercising regularly, it is vital that you eat a healthy, balanced diet to tackle obesity.

According to the NHS, a healthy diet should consist of:

"Try to avoid foods containing high levels of salt because they can raise your blood pressure, which can be dangerous for people who are already obese," warns the the health body.

It adds: "You'll also need to check calorie information for each type of food and drink you consume to make sure you don't go over your daily limit."

The rest is here:
How to live longer: Brisk walking proven to boost longevity - how fast must you walk? - Express

Were all getting used to wearing masks, using hand sanitizer, and standing at least 1 meter apart. One industry that is hoping a new normal can breathe life back into their livelihoods is the world of travel.

Staycations have grown in popularity, which is great for the UK economy. But with tourism worth billions for countries across the globe, it is important that people are still able to see travelling abroad as a viable and safe option during unpredictable times.

In this article, we are going to discuss what the future of holidays may look like today, tomorrow, and in a post-pandemic world, as global economies get to grips with recovering from nearly a year of lockdowns and closures.

The safety of people is paramount when you consider how wildly the virus can spread. We have seen the devastation it can cause without the correct measures in place.

We know the ability to travel abroad hinges on the health of the passenger and the health of the country. This is because of infection rates, especially spikes that raise alarm bells for governments and medical professionals.

The UKs travel corridors are a way of working out which countries are deemed safe to travel to. Were in a situation where you could be in a country one night and everything is okay, to waking up and finding out youll need to quarantine for 14-days on your return.

Its the world we live in right now. Economies need to support each other. But, at the same time, it has to be a case of common sense over cash is king. Were likely to be in a position for quite some time when the rules change overnight. Hopefully, it doesnt completely deter people from booking holidays and visiting new places. That said, hopefully, you respect social distancing and other measures put in place by the country you call your own for a week or two.

Choosing where to stay when you go on holiday isnt just about the room youll sleep in. Food, drink, entertainment, and the fact its going to be full can play on your mind more than the thickness of the duvet.

But during and even for a short time after the global pandemic, a secluded area could be the ideal way to avoid busy pool areas and hungry holiday goers at the buffet. Villas and private apartments can offer luxury, sun, and the all-important peace of mind that youre able to spend time in a family bubble while socially distancing in the more vibrant areas of popular destinations.

Lockdown has given people more time to think and more opportunity to realize what is important for them. Weve seen the rise of home workouts with the likes of Joe Wicks, and now were potentially heading for a rise in wellness retreats, where seclusion and safety is the order of the day. Bali and China are home to some of the most beautiful wellness retreats in the world such as the Sangha Retreat in Yangcheng Island, Suzhou the perfect place to seek self-clarity and serenity. Such is the beauty of this retreat, especially that youll be Googling how to complete a Chinese visa application once you check out the website.

Its easy to speculate about the future of travelling abroad and what a post-pandemicor even a current pandemic holidaylooks like. But its important to remember that the travel, tourism, and cultural tourism industries have been hit hard by the virus. The fact a future can even be talked about is positive. However, the hope is that it doesnt just remain talk and that we continue to move forward with the new normal and the new way to go on holiday.

This is Longevity Live Partner Content

Thomas Bradley is a copywriter at Visa Genie. He has over seven years communications and copywriting experience, having previously worked in the financial services sector and car industry.

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What Will the Future of Holiday Travel Look Like? - Longevity LIVE - Longevity LIVE

LAKE HIAWATHA, NJ - GladysHess, resident of Lake Hiawatha, NJ for more than 25years, will be turning 101 on December 28.

Gladyswas born andraised in New Jersey. She is mother to seven children andcountless grandchildren andgreat-grandchildren.

Gladysnever got her drivers license, andhas navigatedher way around New Jersey andNew York by walking andcatching the local buses. She recentlyretireda few years ago, but still remainsactive - enjoying walks andtraveling.

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Her family andfriends describe her as kind, funny, anddetermined. They also say she has the most interesting stories around- from lunching with Frank Sinatra, to seeing towns transition from gas to electricity, andthe rapid growth of technology (she has a cell phone!)

Two of her many secrets for looking andfeeling good are black coffee andred wine.

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NJ Resident Turning 101 Credits Longevity to Red Wine and Black Coffee - TAPinto.net

Speaking frankly to married clients about the implications of survivorship is a critical service that financial advisors not only can and should provide but also are uniquely suited to address.

Given womens longer life spans and the fact that women in opposite-sex marriages tend to marry men who are older than they are, women often must be prepared to cover their expenses single-handedly for years after their husbands die. Compounding the problem, widowhood will likely occur during a phase of life when health care expenses will be at their highest.

The financial and longevity disparities between women and men create a unique challenge. In our white paper Addressing The Womens Longevity Gap we discuss the challenges women face in retirement, largely stemming from lower working salaries and greater longevity relative to men, making the threat of poverty quite real for millions of women.

Financial advisors have an opportunity to help married men and women plan strategically for the womens longevity gap. A prepared advisor can help women mitigate and potentially even eliminate the unique financial challenges of the longevity gap by taking the following steps:

Make financial plans based on personalized data and actuarial longevity.

Address retirement health care costs today.

Start Social Security optimization planning today (with a focus on survivor benefits).

Discuss finances, including Medicare surcharges, for the surviving spouse.

Plan for end-of-life costs for both partners.

On average, a healthy 65-year-old woman is expected to live to age 89, compared to age 87 for a healthy 65-year-old man, according to actuarial data. Compounding this longevity gap, women tend to marry men two years older than they are, stretching the average length of widowhood by four years or more.

HealthView Services data indicates that a given client might live much longer or much shorter than the average, largely depending on how well or how poorly their health conditions are managed as they age.

Relevant, personalized data and actuarial longevity figures can help advisors pinpoint specific future costs, such as health care expenses. With this information, advisors can develop retirement income plans that are appropriate for their clients expected life spans and avoid overly conservative plans that unnecessarily restrict spending.

Three in five women age 60 and over say they are worried that their health care costs will exceed their retirement income, the National Council on Aging reported. On average, women pay more than men do for health care in retirement, primarily due to womens longer life spans rather than increased use of medical services.

When comparing projected retirement health care costs between a healthy 45-year-old man and his 43-year-old wife, her costs are projected to be about $200,000 more. While that is a large sum, she can fund that amount by investing just $8,000 more today, assuming an investment in a balanced portfolio of 60% stocks and 40% bonds with an average annual return of 6%.

This example demonstrates the value advisors can provide by tackling retirement planning early with couples. The notable lifetime cost increases women face can be offset more easily with early planning for investments and insurance products. Advisors can sharpen the efficacy of these plans by using reliable, personalized actuarial health care cost projections.

Designed to replace 40% of preretirement earnings, Social Security benefits never expire. As a result, women on average collect more years of benefits than men do, but a couples decisions about Social Security will have a major impact on benefit calculations and the wifes income during the longevity gap.

Social Securitys benefit calculations are based on a complex formula that tracks past earnings. Women tend to have lower earnings over their lifetimes due to their pay inequality as well as time spent out of the workforce caregiving for children, parents and spouses. Lower earnings produce a lower primary insurance amount, which is the starting point for all Social Security benefit calculations.

The following strategies can help female clients maximize the stream of income they receive from Social Security.

Delay retirement. Social Security benefits are based on the highest 35 years of Social Security-taxed earnings. Filling as many of those years as possible with employment is beneficial, especially with late-career, high-income years.

Delay Social Security filing age. Claiming benefits at 62, the earliest possible age, permanently reduces an individuals retirement benefits, and yet it is the choice made by about one-third of women. Delaying benefits, especially if still working, ensures that women earn a higher income later.

Optimize Social Security from a household benefit perspective, including survivor benefits. Advisors should help couples maximize household income rather than looking at each spouse separately. Since many women will outlive their husbands, this approach is particularly important. For example, benefits for a man (Paul) who claims Social Security at 70 instead of at 62 will be 76% higher during his lifetime. After his death, his wifes (Judy) survivor benefit would be 60% higher a meaningful increase. As the lower-wage earner, a woman who is eligible for Social Security benefits may begin collecting her husbands benefits and forgo her own, which are likely to be lower for reasons stated earlier.

Plan for benefits from former spouses. Women (and men) may be eligible to collect survivor benefits from a former spouse if they meet certain criteria. Making them aware of all of their claiming options can help maximize the benefits they ultimately receive.

Although Social Security is meant to replace 40% of preretirement income, other savings and investments comprise the remaining income stream and support a consistent standard of living. The sources that fuel retirement income are not treated consistently from either a tax perspective or by Medicare, making this another area where financial advisors have a real opportunity to shine for clients.

Known as means testing, Medicares Income-Related Monthly Adjustment Amount determines the surcharges paid for Medicare Parts B and D. These surcharges vary by income and marital status. But when one spouse dies, the survivors income threshold is reduced by 50%, despite the fact that many may reduce their household income by only 20% after the passing of a spouse. As a result, women may be pushed into higher surcharge brackets, potentially resulting in tens of thousands of dollars of additional costs.

A financial advisor could address this challenge well before it comes up, with the understanding that Medicare measures ones means by modified adjusted gross income. Some forms of income, such as required 401(k) distributions, do count as MAGI; and other forms, such as health savings accounts, life insurance, annuities and Roth IRAs, do not. Therefore, advisors have a significant opportunity to help clients build a balanced portfolio of savings and retirement income vehicles that will limit taxes as well as substantial Medicare surcharges.

Death can come very quickly, or it can be a slow, debilitating and expensive decline, but its an eventuality for all. Being prepared for significant end-of-life care expenses is not something couples will ever regret. Savvy financial advisors can help client couples plan years before retirement for the cost of end-of-life care.

In 20 years, a year of nursing home care is expected to cost $175,000, while a year of assisted living would run $100,000, with dramatic regional variations in costs. This consideration is crucial for women, who, on average, spend about two-and-a-half years in long-term care facilities at the end of life. Thats a full year longer than what the average man experiences because he has his wife to care for him.

Accurately planning for a mans end-of-life care costs is critical to his widows ongoing financial security. But planning for her end-of-life care costs is critical to her experience. It will define whether she has suitable care options for her final years or ends up dependent on state support or her children.

Whether couples choose to buy long-term care coverage or free up additional cash to invest, or both, the steps they take now can help fill the womens longevity gap with financial security.

Understanding their personal health outlook can help guide savings amounts and selection of the most advantaged vehicles to ensure a financially secure retirement and the ability to manage future health care costs without dramatic reductions to the couples hoped-for standard of living.

As their trusted advisor in these sensitive, important areas, you will earn their confidence, trust and referrals. And you will give your clients the invaluable: genuine peace of mind as they age.

Originally posted here:
Take Steps To Bridge The Women's Longevity Gap - Insurance News Net

New Jersey, United States: Market Research Intellect has added a new report to its huge database of research reports, entitled Longevity and Anti-senescence Therapy Market Size and Forecast to 2027. The report offers a comprehensive assessment of the market including insights, historical data, facts, and industry-validated market data. It also covers the projections using appropriate approximations and methods.

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The Longevity and Anti-senescence Therapy Market Report provides comprehensive data on market dynamics, market trends, product growth rate, and price. The Longevity and Anti-senescence Therapy market report has various facts and statistics assuming the future predictions of the upcoming market participants. In addition, it offers business security taking into account sales, profit, market volume, demand and market supply ratio. The in-depth study provides vital information related to market growth, driving factors, major challenges, opportunities, and threats that will prove to be very helpful for market participants in making upcoming decisions.

Longevity and Anti-senescence Therapy Market: Competitive Landscape

The Longevity and Anti-senescence Therapy Market report consists of the Competitive Landscape section which provides a complete and in-depth analysis of current market trends, changing technologies, and enhancements that are of value to companies competing in the market. The report provides an overview of sales, demand, futuristic costs and data supply as well as a growth analysis in the forecast year. The key vendors in the market that are performing the analysis are also clearly presented in the report. Their development plans, their growth approaches, and their merger and acquisition plans are also identified. Information specific to a keyword in each of these regions is also provided. This report also discusses the submarkets of these regions and their growth prospects.

Prominent players operating in the market:

Longevity and Anti-senescence Therapy Market Segmentation

The report contains the market size with 2019 as the base year and an annual forecast up to 2027 in terms of sales (in million USD). For the forecast period mentioned above, estimates for all segments including type and application have been presented on a regional basis. We implemented a combination of top-down and bottom-up approaches to market size and analyzed key regional markets, dynamics and trends for different applications.

Longevity and Anti-senescence Therapy Market Segment by Type:

Longevity and Anti-senescence Therapy Market Segment by Application:

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In the report, experts analyze and forecast the Longevity and Anti-senescence Therapy market on a global as well as regional level. Taking into account all aspects of the market in terms of regions, the focus of the report is on North America, Europe, Asia Pacific, the Middle East and Africa, and South America. The prevailing trends and various opportunities in these regions are studied that can convince the growth of the market in the forecast period 2020 to 2027.

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Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage, and more. These reports deliver an in-depth study of the market with industry analysis, the market value for regions and countries, and trends that are pertinent to the industry.

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Longevity and Anti-senescence Therapy Market Size, Revenue, Share, Scope, Growth Rate And Forecast To 2027 - Cheshire Media

The Aerobics Centre Longitudinal Study, published in Medicine and Science in Sports and Exercise, analysed nearly 13,000 adults.

Three health outcomes were measures - cardiovascular events such as heart and stroke that didnt result in death, all cardiovascular events including death and any type of death.

DC Lee, associate professor of kinesiology, said resistance exercise reduced the risk of all three.

The results are encouraging, but will people make weightlifting part of their lifestyle? Will they do it and stick with it? That's the million-dollar question, he said.

READ MORE:New long-Covid symptom: Coronavirus may cause sufferers teeth to fall out, say dentists

A lot of research on strength training has focused on bone health, physical function and quality of life in older adults.

When it comes to reducing the risk for cardiovascular disease, most people think of running or other cardio activity.

But Less said weight lifting is just as good for your heart, and there are other benefits to be had.

Lee and his colleagues also looked at the relationship between resistance exercise and diabetes, as well as high cholesterol.

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The two studies, published in Mayo Clinic Proceedings, found resistance exercise lowered the risk of both.

Less than an hour of weekly resistance exercise, when compared with no resistance exercise, was associated with a 29 percent lower risk of developing metabolic syndrome - a condition which increases the risk of heart disease, stroke and diabetes.

The risk of high cholesterol was 32 percent lower.

The results for both studies were also independent of aerobic exercise.

"Muscle is the power plant to burn calories. Building muscle helps move your joints and bones, but also there are metabolic benefits. I don't think this is well appreciated," said Lee.

If you build muscle, even if you're not aerobically active, you burn more energy because you have more muscle.

This also helps prevent obesity and provide long-term benefits on various health outcomes."

Weekly resistance exercise is recommended by the NHS.

As part of its physical activity guidelines for adults aged 19 to 64 it advises adults aim to do strengthening activities that work all the major muscles (legs, hips, back, abdomen, chest, shoulders and arms) on at least two days a week.

Adults are also advised to aim to do at least 150 minutes of moderate intensity activity a week or 75 minutes of vigorous intensity activity a week.

You should aim to be physically active every day - any activity is better than none.

And you should reduce time spent sitting or lying down, and break up long periods of not moving with some activity.

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How to live longer: Lifting weights for less than an hour a week could boost longevity - Express

We have been told about the importance of protecting gut health as a measure to take care of overall health. Do you know what probiotics are and what are they for? These live bacterial cultures have become one of the best allies to protect intestinal health. Any gut doctor can advise you on their importance.

They are critical to the synthesis of some essential nutrients and to maintain optimal digestive health. Likewise, they create a protective barrier against infections and act beneficially on some inflammatory processes. Although they exist naturally in the body, they can be consumed through some fermented or dairy foods as well as food supplements. You should look for the best probiotic supplements that will keep your gut in perfect shape.

Probiotics are good bacteria and yeasts. They survive passage through the gastrointestinal tract to implant in the colon and small intestine. Although many associate bacteria with the disease, their role is very different.

Probiotics can stop the excessive growth of infectious microorganisms. Therefore, they are key to preventing the development of various pathogens. Those most used for human benefit are lactobacilli and bifidobacteria.

To sum it up, these non-harmful bacteria and yeasts occupy sites where pathogenic microorganisms could implant. By not leaving room for them and favoring some processes such as digestion, they are beneficial.

The gastrointestinal tract is packed with about 400 bacterial species. Among its primary functions is to protect the body against the proliferation of pathogens responsible for many conditions.

They are also responsible for controlling the differentiation of epithelial cells. They are also involved in metabolic processes and the production of vitamins. Therefore, it is essential to have a balanced intestinal flora rich in healthy bacteria.

Probiotics are the best alternative to improve gut health. Here are the benefits of probiotics.

There is nothing worse than having diarrhea. If youre suffering from diarrhea caused by an infection, probiotics can help you heal faster and lessen the severity of your symptoms. It will get rid of all the elements that bring about stomach pain. Using it will not affect some of the good bacteria in your gut.

Are you taking antibiotics? Probiotics can help rebalance your gut. Taking antibiotics kills the harmful bacteria that are causing your infection. However, it can also kill the good bacteria in your gut, leading to diarrhea in some people. Probiotics can play a pivotal role in replenishing some of the good bacteria destroyed by the drugs.

Irritable Bowel Syndrome is a condition affecting the stomach. It causes severe pain and problems, including constipation, diarrhea, or a combination of the two. It is a syndrome that affects around 10% to 15% of the population. Research shows that bacteria can play an essential role in this syndrome. Probiotics have shown promise in improving IBS symptoms, especially in people who experience diarrhea more often.

Are you going on a trip? Consider bringing probiotics. We all want to focus on the fun things to do, local food, and sightseeing while on vacation. That said, theres nothing worse than having your trip ruined by an unexpected episode of tourista. Fortunately, probiotics containing specific strains of bacteria and yeast have shown promise in this regard. If you plan on taking a probiotic while traveling, remember to choose one that doesnt need to be refrigerated. Ask your pharmacist to help you select a product if in doubt.

Different types of probiotics have other health effects. Many of the effects of probiotics take place via multiple actions of these on the gut flora:

Now that we know what probiotics are for, it is good to know their sources. Here are some of its sources.

Fermented foods contain probiotics. The most popular include:

Not all people get enough probiotics through diet. Considering their importance for health, the option of including them in supplements is an excellent idea. Supplements are available in capsules, powders, and other similar products. These contain large concentrations of microorganisms, beneficial, and protective of health.

Some presentations are enriched with prebiotics, which are foods that promote the growth of these good bacteria. Therefore, in many cases, these products are more effective than the probiotics that come from the traditional diet. In other words, a prebiotic food is one that favors the growth of beneficial microorganisms. And a probiotic is one that directly contains those healthy beings.

Bowel balance is good for your general health. We are learning a lot of things about probiotics every day, and the proof for their benefits keeps growing. If you want to add probiotics to your life, talk to a qualified pharmacist or healthcare professional. They will help choose the product thats best for you.

The gut is regularly referred to as the second brain because the gut microbiome can have a big impact on your body, including the state of your hair. That said, the gut microbiome can be affected by your lifestyle choices and anything that throws it off balance can compromise your health, as well asaffect the health of your locks. So, heres how a healthy gut can help prevent hair loss.

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5 Benefits of Probiotics for Gut Health - Longevity LIVE - Longevity LIVE