StemCell Therapy

The cell therapy technologies market is expected to gain immense growth opportunities through the forecast period of 2019-2029 owing to the rising influence of cell therapies across the life sciences sector. The overwhelming need for novel and enhanced therapies for a variety of diseases and disorders may bring extensive growth prospects for the cell therapy technologies market during the forecast period.

The increased funding by the government may also prove to be a great growth prospect for the cell therapy technologies market. The precision medicine sector is evolving at a rapid rate across the globe. In this, a patient is given personalized treatment and is useful in making more accurate decisions. Thus, this factor may boost the growth of the cell therapy technologies market.

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Cellular therapy is the transplantation of human cells to replace cells or tissues. This therapy can be used for treating various diseases and disorders. The evolution of cell therapy technologies is bringing immense advancements across the sector. This therapy is used mainly for nervous system disorders and cancer. The growing cases of these diseases may further invite promising growth.

On the basis of product, the cell therapy technologies market can be segmented into consumables, cell processing equipment, single-use equipment, other equipment, and systems and software. Based on cell type, the cell therapy technologies market can be classified into stem cells, T-cells, and other cells. Cell therapy technology is utilized expansively in biopharmaceutical and biotechnology companies and CROs, and research institutes and cell banks.

The enhancements in cell therapy technology research through immense investments from various sectors may invite prominent growth prospects for the cell therapy technologies market.

This report has extensive information on a plethora of aspects related to the growth of the cell therapy technologies market. The L.E.A.P mechanism applied by the researchers enables a 360-degree view of the cell therapy technologies market. The CXOs derive the perfect information that allows them to chalk out their business strategy accordingly. This report also has scrutinized information about the novel coronavirus outbreak and its effect on the cell therapy technologies market.

Cell Therapy Technologies Market: Competitive Insights

The cell therapy technologies market is highly fragmented. Numerous players are involved in intense competition for gaining a prominent position among the end-users. The players are also involved in expansion activities through mergers and acquisitions. Some well-entrenched players in the cell therapy technologies market are Danaher Corporation, CellGenix GmbH, IxCells Biotechnology, Wilson Wolf Corporation, SIRION Biotech GmbH, Dickinson and Company, and FUJIFILM Irvine Scientific.

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Cell Therapy Technologies Market: COVID-19 Impact

The COVID-19 impact may offer bright opportunities for the cell therapy technologies market to gain growth. The rising transmission of COVID-19 has led to rapid research and development activities in terms of an effective drug or vaccine. Cell-based research and technologies play an important role in the discovery of vaccines. Hence, this aspect may bring expansive growth prospects for the cell therapy technologies market.

Cell Therapy Technologies Market: Regional Prospects

The cell therapy technologies market in North America may gain a dominant position throughout the forecast period of 2019-2029. The maximizing research and development activities across the region for a good COVID-19 vaccine may bring profitable growth for the cell therapy technologies market. Robust healthcare expenditure, rising disposable income, and growing healthcare awareness may invite promising growth.

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Cell Therapy Technologies Market | Extensive Information on a Plethora of Aspects Related to the Growth of the Market - BioSpace

There may be nothing quite as gut-wrenching as sitting at the bedside of a loved one, watching helplessly as their life comes to an end. Perhaps the only thing more painful is when that loved one no longer recognizes you, slipping away not knowing who it was holding their hand.

November is deemed Alzheimers Awareness Month. Though with the degenerative brain disease now affecting roughly 5.8 million Americans and their families today, its perhaps not so much an increase of awareness thats needed, but rather a desperate need for effective treatment.

Alzheimers is the only disease among the top 10 causes of death in America that cannot be prevented, cured or even slowed. Over a decade and billions of dollars have been spent on research to find a cure for Alzheimers, yet none have thus far proved real clinical benefit. If the elusive cure for Alzheimers isnt found soon, scientists estimate that by 2050 someone in the United States will develop the disease every 33 seconds.

While these statistics paint a pretty bleak picture, Cynthia Lemere, Ph.D., Associate Professor of Neurology at Brigham and Womens Hospital and Harvard Medical School, assured BioSpace that hope is not lost. Despite the many failed drug trials, Lemere says the horizon is finally looking optimistic and expects to see multiple treatments approved within the next few years.

Any therapy developed at this point is going to be probably good for one subsection of that 5.8 million people with Alzheimers disease. And maybe not even that population, but maybe the population that doesnt yet have Alzheimers disease but has the changes going on in their brain of Alzheimers, so we know that theyre on the track, Lemere said.

While no real treatment is yet approved, diagnostic capabilities have grown exponentially. When Lemere first started in the neurology field, a true Alzheimers diagnosis couldnt be given until autopsy. The past decade has shown that the pathology of the disease starts in the brain roughly 20 years before clinical symptoms. PET scans can determine those on a trajectory to develop Alzheimers and with new biomarker testing working towards FDA approval, theyll be able to predict onset of clinical symptoms.

Knowing those who are most likely to develop this degenerative brain disease and when opens opportunities for clinical trials that are in the works. The majority of treatments being developed right now are targeting that window before cognitive decline. There are currently 2,050 interventional studies listed on clinicaltrials.gov around the world for the treatment of AD.

One buzzworthy drug in the news is Biogens aducanumab. Back in March 2019, Biogen stopped two Phase III trials for the antibody drug based on an interim futility analysis that indicated a lack of efficacy. But after a full collection of their data, Biogen found there was indeed efficacy in the higher dosage group who received over 10 doses.

This left them with two very different sets of trial results EMERGE with a positive reading and ENGAGE with a negative. Lemere believes the evidence in the EMERGE trial was strong enough to show positive clinical benefits. Despite much criticism and doubts surrounding aducanumab, Biogen took it to the FDA with hopes for approval and received a harsh vote from an independent advisory committee. No word yet from the FDA. Lemere predicts the FDA will call for another, large Phase III study to confirm the positive result at the higher dose for the full study. Lemere consults with Biogen for the companys Alzheimers education program and is not involved with their drug development programs.

The main breakthrough in the past year for pharmaceutical treatment of AD is that researchers finally know what the right target is - a toxic amyloid oligomer formation that is a key driver for the disease. Biogen isnt the only one targeting it with their drug candidates. Also in the race are Alzheon with ALZ-801, Eisais BAN2401 and Roches gantenerumab.

Unlike the intravenous antibody candidates from the other three, Alzheons ALZ-801 is an orally administered amyloid oligomer inhibitor. Alzheon recently dosed their first patients in a Phase II biomarker study in APOE4 carriers. Patients with an APOE4 gene are at a much higher risk for developing Alzheimers, particularly if you were passed two of the genes. In August, the National Institute of Aging awarded Alzheon an unprecedented $47 million grant to assist with a Phase III clinical trial of ALZ-801. The trial is slated to start at the beginning of next year with a timeline of 2-3 years to complete. This Phase III will be dosing younger people with Alzheimers pathology to test for primary prevention, intervening before clinical symptoms appear.

A Shanghai-based biotech is targeting AD in a completely different way. Instead of targeting amyloid in the brain, Green Valleys candidate is going after the gut. GV-971 is an oral capsule with its primary ingredient derived from seaweed to therapeutically harnesses the abnormal production of amino acids, infiltration of immune cells to the brain, and in turn neuroinflammation via remodeling the gut microbiota. Reactions to this approach range from excitement to cautious optimism to downright skepticism. Time should soon tell if theres something to this approach as Green Valley has now identified its first patient for its Phase III trial in the US with the initial dose coming soon.

Drug developers arent the only ones trying to stop the devastating progression of AD. A research team at MIT found that in Alzheimer's mouse models, the right brain waves can drive microglia, scavenger cells that remove damaged neurons and infections in the central nervous system, to consume the toxic amyloid protein deposits. More research is being done in this area to explore this as a potential option for treatment in humans to reduce amyloid deposits in the brain.

Lemere listed off multiple research projects in the works for Alzheimers prevention therapies to prevent free-radical formation and reduce oxidative stress in the brain, studies into the importance of vascular health and its impact on AD, the effects of diet and exercise, and more. One study found significant results in patients using aggressive blood pressure therapy. People that had lowered their blood pressure and kept it around 120, compared to the control group hovering around 140, showed a significant slowing of the rate of visible cognitive impairment.

The Alzheimers Association, of which Lemere is a member of the medical and scientific advisory group, is sponsoring a lifestyle intervention study in the U.S. called POINTER, that takes into account exercise, nutrition, social interactions, cognitive stimulation and management of comorbidities to protect cognitive function in healthy older adults who are at an increased risk of cognitive decline.

The big point is that probably none of these is going to work by itself, Lemere said.

Rather she sees a future in which a doctor who sees Alzheimers pathology brewing in a patient will recommend a multi-prong defense.

I think its going to be a combination of treatments. And its not going to be the same combination for each person, Lemere said. Its going to be dependent on whatever else is going on with them. Because Alzheimers rarely occurs by itself. There are usually other comorbidities. So ultimately, I think it will be more personalized medicine and combination therapy.

In 2020 alone, the National Institutes of Health is expected to spend $2.8 billion on Alzheimers research. Costing the U.S. $277 billion a year, its the most expensive disease in America. Annual cost of care is projected to increase to $1.1 trillion by 2050. While the financial burden is exorbitantly high, for family members and caregivers its the emotional cost that leaves the deepest scars.

Arkansas resident Linda Crafton knows firsthand the devastating effects Alzheimers has on a family.

To me, its worst disease known to mankind. I used to think the way I lost my dad, which was an instant death, was the hardest way to lose someone, Crafton said. I now know that was wrong. The hardest way to lose your parent is day by day, little by little, an inch at a time.

Craftons mother and five of her mothers seven siblings were victims of the aggressive disease. She said shes in a generation of cousins who now live in fear of the future, wondering which of them will be the first to show the signs, the first to receive their own diagnosis.

Time magazine writer Jeffrey Kluger said, Suffering is always hard to quantify especially when the pain is caused by as cruel a disease as Alzheimer's. Most illnesses attack the body; Alzheimer's destroys the mind and, in the process, annihilates the very self.

Though a cure for Alzheimers has frustrated scientists for years, theyre closer now than theyve ever been before.

According to the Alzheimers Association, a lack of volunteers for clinical trials is one of the greatest obstacles slowing the progress of potential new treatments. If you or someone you love is on a trajectory for the development of Alzheimers disease, the association offers a free TrialMatch service to connect volunteers with clinical trials to advance research.

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Potential for an Alzheimer's Treatment Appears to Be Closer Than Ever - BioSpace

Latest launched research document on Pharma Clinical Trial Digitization Market study of 350 Pages provides detailed analysis with presentable graphs, charts and tables. This report covers a detailed study of the Pharma Clinical Trial Digitization Market size, growth, and share, trends, consumption, segments, application and Forecast 2027. The Research Study presents a complete assessment of the Market and highlights future trend, growth factors & drivers, leaders opinions, facts, and primary validated market data. The research study provides estimates for Pharma Clinical Trial Digitization Forecast till 2027. Pharma Clinical Trial Digitization Report is a comprehensive business study on the current state of industry which analyses innovative strategies for business growth and describes important factors such as top manufacturers, production value, key regions, and growth rate.

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Pharma Clinical Trial Digitization Market is accelerating owing to the demand of personalized medicine. The enhancement in the digital pharma services to keep the track of medication through the various components namely individualized drug printing, drug impact monitoring, bioprinting and others are defining the potential future of the pharma clinical trial digitization market during the forecast period of 2020 to 2027.

This upgradation of healthcare IT infrastructure and technological assistance being provided on vast scale is driving the market growth at the rate of 5.70% annual for the mentioned seven years. This momentum will be maintained by rising practice of individualized drug printing.

Pharma Clinical Trial Digitization Market report covers strategic profiling of key players in the market, comprehensively analyzing their core competencies, and their strategies such as new product launches, expansions, agreements, joint ventures, partnerships, and acquisitions which are applicable for the businesses with which they can take better steps to improve their strategies to sell goods and services. Market research study presents actionable market insights which help create sustainable and money-spinning business strategies. An absolute way to forecast what future holds is to comprehend the trend today. Thus, with this Pharma Clinical Trial Digitization business report, more important aspects of the Pharma Clinical Trial Digitization industry can be focused.

Pharma Clinical Trial Digitization Market Scenario

According to Data Bridge Market Research the Pharma Clinical Trial Digitization market is attaining a significant growth in the developing economies during the forecast period of 2020-2027 due to factors such as introduction of medical robots in hospitals, improving quality life of people, rising popularity of technologically advanced surgical robots and increasing diagnosis of diseases will boost the growth of the market. Pharma Clinical Trial Digitization Market is becoming more competitive every year with surgical robots will expect to attain maximum share during the period of 2020-2027. The Data bridge market research new reports highlight the major growth factors and opportunities in the Pharma Clinical Trial Digitization Market.

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List of Significant Vendors Operating in this market include:

Antidote Technologies, Inc.AparitoClinerion Ltd.CliniOps, Inc.ConsilxDeep 6 AIKoneksa Health Inc.Medidata SolutionsOraclePatientsLikeMeTrialbeeTriNetX, Inc.Veeva Systems.Complete Report is Available (Including Full TOC, List of Tables & Figures, Graphs, and Chart)https://www.databridgemarketresearch.com/toc/?dbmr=global-pharma-clinical-trial-digitization-market&ab

This Pharma Clinical Trial Digitization Market Research document takes into consideration several industry verticals such as company profile, contact details of manufacturer, product specifications, geographical scope, production value, market structures, recent developments, revenue analysis, market shares and possible sales volume of the company. It consists of most-detailed market segmentation, systematic analysis of major market players, trends in consumer and supply chain dynamics, and insights about new geographical markets. The market insights and analysis provided in this market research document are based upon SWOT analysis on which businesses can trust confidently. This Pharma Clinical Trial Digitization report is produced by chewing over several fragments of the present and upcoming market scenario.

Global Pharma Clinical Trial Digitization Market Segments & Geographic Analysis:

By Services (Drug Dose Adjustment, Drug Impact Monitoring, Medical Prescription System, Bioprinting, Preventive Therapy, Individualized Drug Printing)

By Application (Clinical Data Management, Trial Monitoring, Patient Recruitment and Enrollment)

By Themes (Digital Continuity Across Clinical Trial IT Systems, Patient-centric Remote and Virtual Trial Design, Direct-to-patient Home Services)

Pharma Clinical Trial Digitization Market-Geographical Segment

North America (Canada, United States & Mexico)Europe (Germany, the United Kingdom, BeNeLux, France, Russia & Italy)Asia-Pacific (Japan, South Korea, China, India & Southeast Asia)South America (Argentina, Brazil, Peru, Colombia, Etc.)Middle East & Africa (United Arab Emirates, Egypt, Saudi Arabia, Nigeria & South Africa)Global Pharma Clinical Trial Digitization Market Scope and Market Size

Pharma clinical trial digitization market is segmented of the basis of services, application and themes. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

On the basis of services, the pharma clinical trial digitization market is segmented into drug dose adjustment, drug impact monitoring, medical prescription system, bioprinting, preventive therapy, and individualized drug printing.

Based on application, the market is segmented into clinical data management, trial monitoring, patient recruitment and enrollment.

The pharma clinical trial digitization market on the basis of theme is segmented into digital continuity across clinical trial it systems, patient-centric remote and virtual trial design and direct-to-patient home services.

Years considered for this report:o Historical Years: 2010-2019o Base Year: 2019o Estimated Year: 2020o Pharma Clinical Trial Digitization Market Forecast Period: 2020-2027

With tables and figures helping analyses worldwide Global Pharma Clinical Trial Digitization market trends, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

Table of Content:

Market Overview:The report begins with this section where product overview and highlights of product and application segments of the global Pharma Clinical Trial Digitization Market are provided. Highlights of the segmentation study include price, revenue, sales, sales growth rate, and market share by product.

Competition byCompany:Here, the competition in the Worldwide Pharma Clinical Trial Digitization Market is analyzed, By price, revenue, sales, and market share by company, market rate, competitive situations Landscape, and latest trends, merger, expansion, acquisition, and market shares of top companies.

Company Profiles and Sales Data:As the name suggests, this section gives the sales data of key players of the global Pharma Clinical Trial Digitization Market as well as some useful information on their business. It talks about the gross margin, price, revenue, products, and their specifications, type, applications, competitors, manufacturing base, and the main business of key players operating in the global Pharma Clinical Trial Digitization Market.

Market Status and Outlook by Region:In this section, the report discusses about gross margin, sales, revenue, production, market share, CAGR, and market size by region. Here, the global Pharma Clinical Trial Digitization Market is deeply analyzed on the basis of regions and countries such as North America, Europe, China, India, Japan, and the MEA.

Application or End User:This section of the research study shows how different end-user/application segments contribute to the global Pharma Clinical Trial Digitization Market.

Market Forecast:Here, the report offers a complete forecast of the global Pharma Clinical Trial Digitization Market by product, application, and region. It also offers global sales and revenue forecast for all years of the forecast period.

Research Findings and Conclusion:This is one of the last sections of the report where the findings of the analysts and the conclusion of the research study are provided.

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Data Bridge Market Research provides customization of reports as per your need. This report can be personalized to meet your requirements. Get in touch with our sales team (Corporatesales@databridgemarketresearch.com), who will guarantee you to get a report that suits your necessities.

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Pharma Clinical Trial Digitization Market Size, Share, Revenue, Demand and Forecasted Healthcare Industry with Upcoming Trends and Expectations by...

Four New C-Codes for IVL Performed Below the Knee in Hospital Outpatient Setting Four New C-Codes for IVL Performed Below the Knee in Hospital Outpatient Setting

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Centers for Medicare & Medicaid Services Creates New Codes That Establish Specific Payment for Intravascular Lithotripsy Performed Below the Knee

NEW YORK and PETACH TIKVA, Israel, Dec. 04, 2020 (GLOBE NEWSWIRE) -- Y-mAbs Therapeutics, Inc. (Nasdaq: YMAB) (the “Company” or “Y-mAbs”) a commercial-stage biopharmaceutical company focused on the development and commercialization of novel, antibody-based therapeutic products for the treatment of cancer and Takeda Israel, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited (TSE:4502/NYSE:TAK) (“Takeda”) announced today that they have entered into an exclusive license and distribution agreement for the registration and commercialization in Israel of DANYELZA for the treatment of patients with relapsed/refractory high-risk neuroblastoma and omburtamab for the treatment of pediatric patients with CNS/leptomeningeal metastasis from neuroblastoma. DANYELZA (naxitamab-gqgk) was approved by the U.S. FDA on November 25, 2020. Additionally, Y-mAbs plans to resubmit the amended BLA for omburtamab for the treatment of pediatric patients with CNS/leptomeningeal metastasis from neuroblastoma to the FDA by the end of 2020 or in early 2021.

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Y-mAbs and Takeda Announce Exclusive License and Distribution Agreement for DANYELZA® (naxitamab-gqgk) and Omburtamab in Israel

WILLIAMSVILLE, N.Y., Dec. 04, 2020 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (NYSE American: XXII), a leading plant-based, biotechnology company that is focused on tobacco harm reduction, very low nicotine content tobacco, and hemp/cannabis research, announced today that it will be presenting at the 13th Annual LD Micro Main Event Conference on Monday, December 14, 2020, at 9:20 a.m. ET. James A. Mish, chief executive officer of 22nd Century Group, will be presenting to a live, virtual audience.

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22nd Century Group to Present at 13th Annual LD Micro Main Event Conference

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Zynerba Pharmaceuticals Presents New Data in Two Posters at the 2020 Annual Meeting of the American Epilepsy Society (AES)

VALNEVA

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Valneva - Déclaration d’actions et de droits de vote – NOVEMBRE 2020

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Tauriga Sciences Inc. to Further Expand its Product Offerings With Dark Chocolate [20mg] CBD Infused Round Medallions

Basel, December 4, 2020 — Detailed results from the pivotal Phase III REACH3 study demonstrate Jakavi® (ruxolitinib) significantly improved outcomes across a range of efficacy measures in patients with steroid-refractory/dependent chronic graft-versus-host disease (GvHD) compared to best available therapy (BAT)1. The results of REACH3, the first successful, randomized Phase III trial in chronic GvHD, were presented today during the 62nd American Society of Hematology Annual Meeting & Exposition (ASH). REACH3 is jointly sponsored by Novartis and Incyte.

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Novartis announces first data from REACH3 trial showing Jakavi® (ruxolitinib) significantly improved outcomes in patients with...

DECLARATION OF THE NUMBER OF SHARES AND VOTING RIGHTS

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Virbac : Declaration of the number of shares and voting rights 11/2020

Mechelen, Belgium; 4 December 2020, 22.01 CET; regulated information – Galapagos NV (Euronext & NASDAQ: GLPG) announces a share capital increase arising from subscription right exercises.

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Galapagos increases share capital through subscription right exercises

SAN JOSE, Dec. 04, 2020 (GLOBE NEWSWIRE) -- Anpac Bio-Medical Science Co., Ltd. (“Anpac Bio,” the “Company” or “we”) (ANPC), a biotechnology company with operations in China and the United States focused on early cancer screening and detection, announced today the resignation of Ernst & Young Hua Ming LLP ("EY"), which previously was the independent registered public accounting firm of Anpac Bio, on November 3, 2020 and the appointment of Friedman LLP ("Friedman") as the Company's independent registered public accounting firm on December 2, 2020 to conduct the audit for the fiscal year ended December 31, 2020.   The appointment of Friedman has been approved by both the audit committee and the board of directors (the "Board") of the Company. The change was not made due to any disagreements with EY.

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Anpac Bio Announces Change of Auditor

WALTHAM, Mass., Dec. 04, 2020 (GLOBE NEWSWIRE) -- Apellis Pharmaceuticals, Inc. (Nasdaq: APLS), a global biopharmaceutical company and leader in targeted C3 therapies, today announced that the company approved the grant of equity awards to two new employees with grant date of December 1, 2020, as equity inducement awards outside of the company's 2017 Stock Incentive Plan (but under the terms of the 2020 Inducement Stock Incentive Plan) and material to the employees’ acceptance of employment with the company. The equity awards were approved on October 27, 2020 and November 16, 2020, in accordance with Nasdaq Listing Rule 5635(c)(4).

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Apellis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Basel, December 5, 2020 — Novartis announced analyses from two separate trials with Kymriah® (tisagenlecleucel) in patients with certain advanced lymphomas. In the interim analysis of the investigational Phase II ELARA study, Kymriah led to a complete response (CR) in 65% of patients with relapsed or refractory (r/r) follicular lymphoma (FL) and an overall response rate (ORR) of 83% after at least three months of follow-up. These patients continued to relapse or have refractory disease despite exposure to numerous lines of therapy (median four prior lines of therapy [range 2-13]) prior to Kymriah infusion1. The second analysis – a 40-month median follow-up from the Phase II JULIET trial – reported that the two-year progression-free survival (PFS) rate was 33% in patients with r/r diffuse large B-cell lymphoma (DLBCL), an important finding given these patients have limited treatment options that provide durable responses2. The JULIET study continued to show the effectiveness and well-characterized safety profile of Kymriah for these patients. These results were presented today during the 62nd American Society of Hematology Annual Meeting & Exposition (ASH).

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Novartis analyses confirm benefit of Kymriah® with clinically meaningful rates of complete response seen in patients with certain advanced lymphomas

CAMBRIDGE, Mass., Dec. 05, 2020 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc. (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases, today announced that preclinical data with FTX-6058 for the treatment of sickle cell disease will be presented in three posters at the virtual 62nd American Society of Hematology (ASH) Annual Meeting and Exposition taking place December 5-8, 2020. FTX-6058 is a highly potent small molecule EED inhibitor that induces expression of fetal hemoglobin (HbF). Elevating HbF can compensate for the mutated adult hemoglobin that has been identified as the root cause of several hemoglobinopathies and can ameliorate or eliminate the symptoms of sickle cell disease.

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Fulcrum Therapeutics Presents Updated Data on Sickle Cell Disease Program at the 62nd American Society of Hematology (ASH) Annual Meeting and...

Data support novel approach to develop and manufacture a best-in-class, durable medicine for people living with hemoglobinopathies

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Editas Medicine Announces Preclinical Data and Large-Scale Manufacturing Process for EDIT-301, in Development for the Treatment of Sickle Cell Disease...

CAMBRIDGE, Mass., Dec. 05, 2020 (GLOBE NEWSWIRE) -- Intellia Therapeutics, Inc. (NASDAQ:NTLA), is presenting new preclinical data in support of NTLA-5001, the company’s wholly owned Wilms’ Tumor 1 (WT1)-directed T cell receptor (TCR)-T cell therapy candidate for the treatment of acute myeloid leukemia (AML), at the 62nd American Society of Hematology (ASH) Annual Meeting, taking place virtually from December 5-8, 2020. NTLA-5001 capitalizes on how natural T cells recognize and respond to tumors. The target, WT1, is highly overexpressed in AML, a cancer of the blood and bone marrow that is often fatal despite existing treatments (NIH SEER Cancer Stat Facts: Leukemia – AML). The new preclinical data being presented today highlight the faster expansion and superior function of T cells manufactured by Intellia’s proprietary approach, compared to a standard genome editing process. Specifically, NTLA-5001’s lead TCR-T cells resulted in significantly higher anti-tumor activity in mouse models of acute leukemias than that observed in mice treated with cells engineered using the standard process.

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Intellia Therapeutics Presents New Preclinical Data Supporting Its CRISPR/Cas9-Engineered TCR-T Cell Treatment for Acute Myeloid Leukemia at the...

SOUTH SAN FRANCISCO, Calif., Dec. 05, 2020 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) therapies for cancer, today announced positive initial results from the Phase 1 UNIVERSAL study of ALLO-715 in relapsed/refractory multiple myeloma (MM). Data were presented at an oral session of the American Society of Hematology (ASH) annual meeting. This study utilizes ALLO-647, Allogene's anti-CD52 monoclonal antibody (mAb), as a part of its differentiated lymphodepletion regimen.

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Allogene Therapeutics Reports Positive Initial Results from Phase 1 UNIVERSAL Study of ALLO-715 AlloCAR T™ Cell Therapy in Relapsed/Refractory...

- Beta thalassemia: All seven patients were transfusion independent with 3 to 18 months of follow-up after CTX001 infusion -

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CRISPR Therapeutics and Vertex Present New Data for Investigational CRISPR/Cas9 Gene-Editing Therapy, CTX001™ at American Society of Hematology...