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Holiday Season Anxiety: What Are The Worst Foods To Eat? – Longevity LIVE – Longevity LIVE

December 8th, 2021 1:57 am

When it comes to anxiety, its not a rare problem. In fact, about 40 million Americans live with anxiety disorders. Over the festive season, anxiety can become even worse, especially if you have a tense relationship with some of your family. Generally, we can manage to avoid those family members that are difficult to deal with for the duration of the year. But over the holiday season, it can often feel like we are pressured into seeing all of our family. This can cause even more anxiety and stress. Strangely, though, it seems that some foods are linked to anxiety and may even trigger it. So what are these foods and could avoiding them around the holiday season help?

Bizarrely, we often tend to use alcohol as a crutch and a way to manage anxiety, especially in social situations where we feel uncomfortable. Generally, the holiday season also sees us consuming more alcohol than we might in the normal course of events. Its no secret that alcohol can have a negative impact on hydration and sleep.

Erin Palinski-Wade, RD, CDE explains it can trigger anxiety symptoms. Technically, alcohol is a depressant that can make you feel calmer. But actually, usually, this backfires. Another thing that alcohol does is change the levels of serotonin and neurotransmitters in the brain. Not only can this make the anxiety worse when youre drinking, but once the alcohol wears off, you may feel even more anxious than before.

Drinking on an empty stomach is a particularly bad idea as it can lead to a severe spike in blood sugar which can trigger feelings of anxiety. If you do want to have a drink, its best to do so in moderation and make sure that your alcohol intake is not excessive. Healthline recommends about 1 drink per day for women and 2 drinks per day for men. Of course, if you are on medication, its also a good idea to check in with your doctor. If you dont want to feel left out but want to avoid drinking, mocktails or alcohol-free beer are typically good options.

Rather frustratingly is that you, like me, are a bit of a coffee fiend, caffeine really inns your best friend if you suffer from anxiety. The more caffeine you consume, the more likely it is to cause anxiety. Dr. Daniel Devine, a Philadelphia-based, dual-board certified internist, and geriatrician explain that the

Liderina/Shutterstock

effects seem to be most prominent in those that consume five or more cups of coffee per day. Of course, this depends on your tolerance levels, so its best to try to ascertain what works for you and what your personal limits are.

The reason behind this seems to be the fact that it activates adenosine receptors in the central nervous system. These receptors are linked to the mediation of the fight or flight response. In general, caffeine is perfectly safe as long as you dont have too much. It is however important to mention that coffee isnt the only thing that contains caffeine, and its important to think about other foods and drinks that might contain it. The FDA recommends a daily caffeine intake of no more than 400 mg. For reference, the average grande medium roast coffee from Starbucks contains about 310 mg of caffeine.

Its important to start off with the fact that not all sugar is bad for you. And theres no way to completely avoid it, especially over the holiday season. The real culprit is added sugar. It has a nasty effect on your blood sugar levels. This rollercoaster also causes spikes and dips in energy and when your blood sugar crashes, it can cause a decline in mood and this is when anxiety levels tend to spike.

This happens as the body releases insulin in an attempt to stabilize blood sugar levels. However, this results in the body working harder in order to get back to

Photo by Andres Ayrton from Pexels

normal. This is what causes those nasty highs and lows. And it isnt just your usual culprits of soft drinks, cakes, and biscuits, there are a whole host of unlikely foods to watch out for, including:

If you already suffer from anxiety and are worried about becoming even more anxious over the holiday season, you might also be able to look to your plate. There seems to be no doubt that there is a direct connection between blood sugar levels and anxiety levels.

Making sure that you monitor and regulate your alcohol intake, caffeine, and sugar levels could definitely help you to combat anxiety. Of course, its definitely not a cure for it and, if you are on medication, make sure that you keep taking it as you should, especially during a time that can cause high stress and anxiety levels.

https://health.usnews.com/wellness/food/articles/foods-and-drinks-linked-to-anxiety

https://www.healthline.com/health/mental-health/surprising-foods-trigger-anxiety?slot_pos=article_1&utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=generalhealth&utm_content=2021-11-08&apid=37389314&rvid=79199d9de2b1a6fe12578e0247f02df8428514e8feeee772acc106b4d6f580e5

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New study finds serious COVID-19 infection could be fatal even after recovery | TheHill – The Hill

December 8th, 2021 1:57 am

People who have recovered from a serious bout of COVID-19 may still have reason to be concerned for their health within the year of their recovery.

A new study published in the journal Frontiers in Medicine suggests survivors of severe COVID-19 are more than twice as likely to die within a year after infection compared to patients who tested negative for the disease or experienced only mild symptoms.

Researchers from the University of Florida analyzed electronic health records of 13,638 patients who were tested for the virus using a PCR test in the Florida health system. Among those tested, 178 patients experienced severe symptoms and were hospitalized while 246 had only mild or moderate symptoms. The rest tested negative for the virus.

The study tracked patients over 12 months after they fully recovered and found those who had severe COVID-19 were 233 percent more likely to die.

Our country is in a historic fight against the coronavirus. Add Changing America to your Facebook or Twitter feed to stay on top of the news.

COVID-19 is even more devastating than we thought when only focusing on the initial episode. The downstream risk for the most severe outcome, death, is definitely high enough to hopefully make everyone rethink the impact of COVID-19, Arch G. Mainous, a professor at the University of Florida and the studys lead author, said in a statement.

Most deaths among severe COVID-19 survivors were not attributed to complications commonly associated with the disease, such as cardiovascular, respiratory and clotting problems. Just 20 percent of deaths were associated with these issues while the majority were the result of a variety of other conditions not typically associated with the coronavirus.

Surprisingly, the study found the increased risk of dying was greater for severe COVID-19 patients under 65.

Researchers said the study underscores the importance of vaccinations in reducing severe disease.

These findings reinforce that the internal trauma of being sick enough to be hospitalized with COVID-19 has a big consequence for peoples health. This is a huge complication of COVID-19 that has not been shown before, Mainous said.

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Lifeist Subsidiary Mikra Cellular Sciences to Launch First Product CELLF to Combat Brain Fog and Unlock Healthy Aging, Announces U.S. Patent…

December 8th, 2021 1:57 am

- Mikra patent focusing on novel cellular therapeutic targeting systemic fatigue- Mikra partners with InVivo Biosystems for pre-clinical trials to strengthen patent application and generate further data confirming expression pathways for genes

TORONTO, Dec. 06, 2021 (GLOBE NEWSWIRE) -- Lifeist Wellness Inc. (Lifeist or the Company) (TSXV: LFST) (FRANKFURT: M5B) (OTCMKTS: NXTTF), a health-tech company that leverages advancements in science and technology to enable you to find your path to wellness, today announced that its newly launched biosciences and consumer wellness subsidiary, Mikra Cellular Sciences Inc. (Mikra), is poised to launch its first product CELLF, a novel cellular therapeutic compound targeting systemic fatigue. As part of pre-launch activities of CELLF, Mikra has filed a patent application with the United States Patent and Trademark Office and partnered with InVivo Biosystems, Inc. (InVivo Biosystems) for pre-clinical trials to strengthen its patent claim.

The real health crisis isnt reduced longevity were living longer than we have in the past. Its extended morbidity thats the problem. While were all familiar with mortality, morbidity is attributable to age-related diseases that lower your quality of life which is why so many of us when we hit our 30s, 40s and 50s experience multiple physiological and mental walls notably brain fog, fatigue, and inflammation. This all happens at a cellular level, and it can cascade into poor sleep, mood drops, and an inability to enjoy life like you want to, said Faraaz Jamal, COO of Lifeist and CEO of Mikra. With that in mind, Im extremely excited to present Mikras first product, CELLF (pronounced self). We engineered this product for everyone who has started to feel like their biological age is affecting their everyday performance and ability to feel like the best version of themselves.

Continued Jamal, CELLF works at a cellular level to help combat systemic fatigue, inflammation, and brain fog by promoting the creation of mitochondria and subsequently increasing their efficiency. This is in addition to the upregulation and downregulation of certain cellular detoxification pathways that can remove the buildup of senescent (old/dysfunctional) cells that may cause excessive chronic inflammation and uncontrolled cell division.

CELLF - A science-backed cellular therapeutic, treating systemic fatigue and low-grade cellular inflammation

CELLF is manufactured in a proprietary oxygen-deprived environment to maintain biopotency and bioavailability with clinically tested United States Food & Drug Administration (FDA) certified GRAS (generally recognized as safe) bioactive ingredients. The CELLF compound delivery system is a two-stage, patented mechanism it is first bound to a transferrin glycoprotein and then encapsulated within a liposome. This allows safe passage of CELLF through the gastric environment and delivery directly into the blood plasma. The result is optimal delivery of our compound with minimal degradation to the best site of absorption. CELLF will be shipped in a package containing 30 X 10ml single-serve sachets to prevent oxidation and maximize bioavailability.

Youve got to satisfy two conditions for a product like this to work. The first is that the molecules within the compound need to be backed by rigorous science. The second is that you need to deliver it effectively into your body, and more specifically, your cells so that it is maximally absorbed. Very few products satisfy the first, let alone the second, said Jamal. As one of my lifelong heroes, Carl Sagan once said, extraordinary claims require extraordinary evidence, which is why weve partnered with Invivo Biosystems to prove and strengthen our patent claim that CELLF does both.

Mikra Partners with InVivo Biosystems

Mikra has partnered with InVivo Biosystems, experts in genetic model creation and in vivo testing, to strengthen its patent application by conducting a pre-clinical study identifying genetic signatures and pathways associated with average human healthspans and to test the effects of CELLF on healthy aging.

We are proud to partner with Mikra in developing a family of healthy living products that reduce biological aging. At InVivo Biosystems, we take a systematic, multi-omics approach to make gene-by-gene discoveries and uncover the different genetic pathways that are up or down regulated during aging. The InVivo Longevity Platform measures the complex interplay of cellular proliferation, autophagy, mitochondrial oxidative stress, genetic predisposition, and transcriptional changes that occur during aging, said Chris Hopkins, PhD, Chief Science Officer at InVivo Biosystems. In our collaboration with Mikra, we are exploring how its flagship formulation, CELLF, increases the efficiency of mitochondrial ATP production and cellular respiration. Using the InVivo Longevity Platform, we measure at the molecular level how Mikras CELLF formulation can counter periodic bouts of fatigue by providing improved cellular respiration. In our partnership, we will be generating the science-based evidence that Mikra can use as further backbone for their intellectual property claims. Here at InVivo Biosystems we are also excited to continue partnering with Mikra in the future to uncover further how CELLF, and their future product lines, can create a new baseline for healthy living after 30.

CELLF Product & Community Launch

Im very excited about adding incremental value to Lifeist shareholders and unlocking the earnings potential of Mikra and subsequently Lifeist. Were taking the first steps here with bringing something novel to the market, validating and protecting it. But lets be clear, its only the first step, said Meni Morim, CEO of Lifeist. The initial traction Mikra has had around the pre-launch has been very promising to grow to a community of nearly 20,000 with a huge level of engagement, in such a short amount of time and with no sign of stopping is a testament to the teams expertise and validates the consumers desire for this type of product.

Mikras CELLF will be available for pre-sale in mid-Q1 2022 with a waitlist sign up available at http://www.wearemikra.com. CELLF will be available on http://www.wearemikra.com and Amazon following the pre-sale for full public launch.

Follow Mikras journey on your favorite social media platform with @wearemikra.

About Mikra, Cellular Sciences Inc.Mikra is a biological sciences and consumer wellness company on a mission to increase your healthspan by focusing on the tiniest aspect of your health: the cell. People are made up of over 37 trillion cells with a variety of different sizes, shapes, functions and lifespan. These cells are responsible for energy, happiness, recovery potential and so much more. Mikra is exploring the link between changes at a cellular level and the cascading effects it can have on health.

About InVivo Biosystems, Inc.InVivo Biosystems, an expert in genetics, delivers scientific proof and evidence for ingredients at the molecular and cellular level via a proprietary analytical approach. Its analytical platform helps branded ingredient developers and manufacturers substantiate their product claims, file IP patents, or refine their formulations using the best science backed measure of outcome. Managed by experienced PhD scientists, InVivo Biosystems gene expression platform can help find new applications for novel ingredients, discover new molecules, and conduct proof-of-concept studies for therapeutic purposes. Visit http://www.invivobiosystems.com/longevity for more information.

About Lifeist Wellness Inc.Sitting at the forefront of the post-pandemic wellness revolution, Lifeist is a portfolio of wellness companies leveraging advancements in science and technology to enable individuals to find their personalized path to wellness. Portfolio business units include: CannMart, which operates a B2B wholesale distribution business facilitating recreational sales to Canadian provincial government control boards and the CannMart.com marketplace which provides Canadian medical customers with a diverse selection of cannabis products from a multitude of federally licensed cultivators and its U.S. customers with access to hemp-derived CBD and smoking accessories; Australian Vapes, the countrys largest online retailer of vaporizers and accessories; Findify, a leading AI-powered search and discovery platform; and Mikra, a biosciences and consumer wellness company seeking to develop innovative therapies for cellular health and recovery.

Information on Lifeist and its businesses can be accessed through the links below:www.lifeist.com http://www.cannmart.com http://www.everyonedoesit.co.uk http://www.australianvaporizers.com.au http://www.wearemikra.com

Contacts

Lifeist Wellness Inc.Meni Morim, CEOMatt Chesler, CFA, Investor RelationsPh: 647-362-0390Email: ir@lifeist.com

Forward Looking Information

This news release contains forward-looking information within the meaning of applicable securities laws. All statements contained herein that are not historical in nature contain forward-looking information. Forward-looking information can be identified by words or phrases such as may, expect, likely, should, would, plan, anticipate, intend, potential, proposed, estimate, believe or the negative of these terms, or other similar words, expressions and grammatical variations thereof, or statements that certain events or conditions may or will happen.

The forward-looking information contained herein, including, without limitation, statements related to the launch of Mikras first product CELLF and its anticipated therapeutic benefits, are made as of the date of this press release and is based on assumptions management believed to be reasonable at the time such statements were made, including, without limitation, expectations that pre-clinical trials will prove successful and that the Companys application for a patent will be granted, expectations that CELLF will gain market acceptance along with the expansion of the market for nutraceutical products and managements perceptions of Lifeists standing in the online marketplace for wellness and related products, Lifeists beliefs regarding the expected demand for wellness and related products and the expected growth of that market, the timing of product availability, as well as other considerations that are believed to be appropriate in the circumstances. While we consider these assumptions to be reasonable based on information currently available to management, there is no assurance that such expectations will prove to be correct. By its nature, forward-looking information is subject to inherent risks and uncertainties that may be general or specific and which give rise to the possibility that expectations, forecasts, predictions, projections or conclusions will not prove to be accurate, that assumptions may not be correct and that objectives, strategic goals and priorities will not be achieved. A variety of factors, including known and unknown risks, many of which are beyond our control, could cause actual results to differ materially from the forward-looking information in this press release. Such factors include, without limitation: unforeseen developments that would delay the Companys ability to launch CELLF as anticipated and in a timely manner, the risk that pre-clinical trials are not as successful as anticipated and do not demonstrate anticipated therapeutic benefits and/or fail to strengthen the Companys patent claim, the risk that the expected demand for nutraceutical products in general and those of the Company does not develop as anticipated, regulatory risk, risks relating to the Companys ability to execute its business strategy and the benefits realizable therefrom and risks specifically related to the Companys operations. Additional risk factors can also be found in the Companys current MD&A and annual information form, both of which have been filed under the Companys SEDAR profile at http://www.sedar.com. Readers are cautioned not to put undue reliance on forward-looking information. The Company undertakes no obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as required by applicable law. Forward-looking statements contained in this news release are expressly qualified by this cautionary statement.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release or has in any way approved or disapproved of the contents of this press release.

Source: Lifeist Wellness Inc.

Photos accompanying this announcement are available at:

https://www.globenewswire.com/NewsRoom/AttachmentNg/0629e54e-48ba-4759-a4ce-344d1b6cc525

https://www.globenewswire.com/NewsRoom/AttachmentNg/4e7b131b-e5d1-4e28-a67d-7fb10c3f7dba

https://www.globenewswire.com/NewsRoom/AttachmentNg/2f4c14b5-6aa9-44f9-8553-648e1e96a21a

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Lifeist Subsidiary Mikra Cellular Sciences to Launch First Product CELLF to Combat Brain Fog and Unlock Healthy Aging, Announces U.S. Patent...

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Cataracts in Dogs: Symptoms, Treatment, Prevention & More

December 8th, 2021 1:56 am

In this Article In this Article In this Article

Dogs' eyes are not that different from our own. They have pupils, corneas, lenses, rods, and cones that work similar to ours, although they see things a little differently.

Since their eyes are similar, they can develop some of the same eye conditions that we do. One of the eye conditions our canine friends share with us is cataracts or clouded eye lenses.

Its important to know what cataracts are, how dog cataracts are caused, and what veterinarians can do to treat them. This way, you can take measures to reduce the chances of your dog developing cataracts and get them the treatment they need.

As they age, dogs develop cataracts in much the same way that humans do. A cloudy film sets into the eyes lens and keeps light from entering.

Your dog's eyes have water and proteins in them. Cataracts form when the proteins begin to clump together and form into a cloud-like substance in the eyes lens.

More and more proteins gather, eventually clouding the entire lens. Cataracts can start small and grow large, or they can appear overnight and completely blind your dog.

Cataracts are an inheritable trait, so if a dog is one of the breeds known for cataracts, there is a good chance they might develop them.

Diabetes Mellitus (sugar diabetes) can also cause cataracts in dogs.

Its also possible for eye injuries, which can cause inflammation, to lead to cataracts. Age is another leading cause of cataract development, appearing suddenly without an underlying condition.

It's important to know that another condition is similar to cataracts nuclear sclerosis, or hardening of the lenses as your dog ages.

This condition causes their eyes to become more cloudy but does not cause blindness. Your dog can see even though their eye lenses have changed. Your veterinarian will examine your dogs eyes to determine if they have nuclear sclerosis or cataracts.

Dogs eye structures change as they age, much like ours do. If your dog is aging and begins to develop a cloudy look in their eyes, or if they have an underlying eye disease cataracts can start to appear.

They might stay small or grow, depending on the condition that has caused them and where they are in the lens. If cataracts develop because your dog has diabetes, they might expand rapidly to cover the entire lens.

When a dog with cataracts is left untreated, they can become blind. The cataract completely blocks light from entering the eye through the lens and keeps your dog from seeing. The condition is still treatable at that time with surgery, but without treatment, it can develop into glaucoma.

Glaucoma is a condition where there is too much pressure in the eye, which damages the optic nerve. If the nerve is damaged, your dog will be permanently blind in the eye where the nerve sustained the damage.

Its important to note that not all cataracts can lead to glaucoma or blindness. Sometimes, they develop only enough to cause some reduction in sight.

Glaucoma isnt the only condition that can be caused by untreated cataracts. Another is lens luxation, or a condition where the lens can float around out of place. Cataract dissolution, where the cataracts dissolve on their own, can cause deep inflammation within the eye and lead to uveitis or glaucoma.

Uveitis is an inflammatory condition within the eye that is painful for your dog and can cause blindness.

All dogs can develop cataracts, but some breeds are more prone to the condition because of genetic traits.

Some of these are:

Your veterinarian will examine your dogs eyes using a light. Veterinarians also use blood tests to determine if any underlying conditions might have caused your dog's cataracts.

In most cases, you cannot prevent cataracts, but there are ways to ensure that your dogs vision is preserved, especially if a medical condition like diabetes causes it. These include:

One of the goals of cataract surgery in canines is to return functional vision. There are no known remedies that can reverse the forming of a cataract surgery is the only option for cataracts once they have formed.

Cataracts are removed with a surgical procedure under general anesthesia. The lens is removed, and the veterinarian replaces it with a lens made from plastic or acrylic. There may only be a need to operate on one eye, or the veterinary ophthalmologist may need to perform the procedure on both eyes.

Veterinarians also run tests to look for underlying conditions that are known to cause cataracts. Treating any conditions that can cause cataracts to form is essential because it reduces the chances that those conditions might cause further health issues.

Your dogs eyes will be sensitive after the surgery, so they have to be placed into a protective collar to keep them from rubbing them and causing damage. Veterinarians also give you eye drops to put in your dogs eyes a few times per day to keep them moisturized and let them heal correctly.

Your pet will need to rest and stay in a calm environment for a few weeks as their eyes heal. If you notice any complications, notify your veterinarian immediately.

Surgery for canine cataracts can be costly. The procedure itself can cost up to a few thousand dollars per eye. If your dog has any underlying conditions, the costs continue to rise as you continue visiting the office and your veterinarian prescribes medications for them.

Depending on the severity of your dogs health and cataracts, you might face medical bills of over $5,000. In general, pre-operative costs are between $500 and $1,000, while the price of surgery ranges from $3,000 to $4,500.

While this might seem steep, when everything is complete, your dog will see you again and be able to enjoy time with you to the fullest. Be sure to monitor your dog's eye after cataract procedure, because they can still develop glaucoma and other eye conditions after surgery.

WebMD Medical Reference Reviewed by Vanessa Farner, DVM on February 10, 2021

Sources:

American College of Veterinary Ophthalmologists: Cataracts.

American Kennel Club: Cataracts Can Occur as Your Dog Ages.

American Kennel Club: Cloudy Eyes in Dogs.

American Kennel Club Canine Health Foundation: 2061: Emergence of Pigmentary Uveitis as a Potential Cause of Cataracts and Glaucoma.

National Eye Institute: Cataracts.

The Royal Society Publishing: Colour cues proved to be more informative for dogs than brightness.

UC Davis Veterinary Medicine Veterinary Genetics Laboratory: Hereditary Cataracts in Australian Shepherds.

Veterinary Partner: Cataracts in Dogs and Cats.

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Diabetic Eye Disease | NIDDK

December 8th, 2021 1:56 am

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Diabetic eye disease is a group of eye problems that can affect people with diabetes. These conditions include diabetic retinopathy, diabetic macular edema, cataracts, and glaucoma.

Over time, diabetes can cause damage to your eyes that can lead to poor vision or even blindness. But you can take steps to prevent diabetic eye disease, or keep it from getting worse, by taking care of your diabetes.

The best ways to manage your diabetes and keep your eyes healthy are to

Photo courtesy of the National Eye Institute, NIH.

Often, there are no warning signs of diabetic eye disease or vision loss when damage first develops. A full, dilated eye exam helps your doctor find and treat eye problems earlyoften before much vision loss can occur.

Diabetes affects your eyes when your blood glucose, also called blood sugar, is too high.

In the short term, you are not likely to have vision loss from high blood glucose. People sometimes have blurry vision for a few days or weeks when theyre changing their diabetes care plan or medicines. High glucose can change fluid levels or cause swelling in the tissues of your eyes that help you to focus, causing blurred vision. This type of blurry vision is temporary and goes away when your glucose level gets closer to normal.

If your blood glucose stays high over time, it can damage the tiny blood vessels in the back of your eyes. This damage can begin during prediabetes, when blood glucose is higher than normal, but not high enough for you to be diagnosed with diabetes. Damaged blood vessels may leak fluid and cause swelling. New, weak blood vessels may also begin to grow. These blood vessels can bleed into the middle part of the eye, lead to scarring, or cause dangerously high pressure inside your eye.

Most serious diabetic eye diseases begin with blood vessel problems. The four eye diseases that can threaten your sight are

The retina is the inner lining at the back of each eye. The retina senses light and turns it into signals that your brain decodes, so you can see the world around you. Damaged blood vessels can harm the retina, causing a disease called diabetic retinopathy.

In early diabetic retinopathy, blood vessels can weaken, bulge, or leak into the retina. This stage is called nonproliferative diabetic retinopathy.

If the disease gets worse, some blood vessels close off, which causes new blood vessels to grow, or proliferate, on the surface of the retina. This stage is called proliferative diabetic retinopathy. These abnormal new blood vessels can lead to serious vision problems.

Photo courtesy of the National Eye Institute, NIH.

Photo courtesy of the National Eye Institute, NIH.

The part of your retina that you need for reading, driving, and seeing faces is called the macula. Diabetes can lead to swelling in the macula, which is called diabetic macular edema. Over time, this disease can destroy the sharp vision in this part of the eye, leading to partial vision loss or blindness. Macular edema usually develops in people who already have other signs of diabetic retinopathy.

Glaucoma is a group of eye diseases that can damage the optic nervethe bundle of nerves that connects the eye to the brain. Diabetes doubles the chances of having glaucoma, which can lead to vision loss and blindness if not treated early.

Symptoms depend on which type of glaucoma you have. Learn more about glaucoma.

Photo courtesy of the National Eye Institute, NIH.

The lenses within our eyes are clear structures that help provide sharp visionbut they tend to become cloudy as we age. People with diabetes are more likely to develop cloudy lenses, called cataracts. People with diabetes can develop cataracts at an earlier age than people without diabetes. Researchers think that high glucose levels cause deposits to build up in the lenses of your eyes.

Photo courtesy of the National Eye Institute, NIH.

About one in three people with diabetes who are older than age 40 already have some signs of diabetic retinopathy.1 Diabetic retinopathy is the most common cause of vision loss in people with diabetes. Each persons outlook for the future, however, depends in large part on regular care. Finding and treating diabetic retinopathy early can reduce the risk of blindness by 95 percent.

Your chances of developing glaucoma or cataracts are about twice that of someone without diabetes.

Anyone with diabetes can develop diabetic eye disease. Your risk is greater with

High blood cholesterol and smoking may also raise your risk for diabetic eye disease.

Some groups are affected more than others. African Americans, American Indians and Alaska Natives, Hispanics/Latinos, Pacific Islanders, and older adults are at greater risk of losing vision or going blind from diabetes.

If you have diabetes and become pregnant, you can develop eye problems very quickly during your pregnancy. If you already have some diabetic retinopathy, it can get worse during pregnancy. Changes that help your body support a growing baby may put stress on the blood vessels in your eyes. Your health care team will suggest regular eye exams during pregnancy to catch and treat problems early and protect your vision.

Diabetes that occurs only during pregnancy, called gestational diabetes, does not usually cause eye problems. Researchers aren't sure why this is the case.

Your chances of developing diabetic eye disease increase the longer you have diabetes.

Often there are no early symptoms of diabetic eye disease. You may have no pain and no change in your vision as damage begins to grow inside your eyes, particularly with diabetic retinopathy.

When symptoms do occur, they may include

Talk with your eye doctor if you have any of these symptoms.

Call a doctor right away if you notice sudden changes to your vision, including flashes of light or many more spots (floaters) than usual. You also should see a doctor right away if it looks like a curtain is pulled over your eyes. These changes in your sight can be symptoms of a detached retina, which is a medical emergency.

Having a full, dilated eye exam is the best way to check for eye problems from diabetes. Your doctor will place drops in your eyes to widen your pupils. This allows the doctor to examine a larger area at the back of each eye, using a special magnifying lens. Your vision will be blurry for a few hours after a dilated exam.

Your doctor will also

Your doctor may suggest other tests, too, depending on your health history.

Most people with diabetes should see an eye care professional once a year for a complete eye exam. Your own health care team may suggest a different plan, based on your type of diabetes and the time since you were first diagnosed.

Eye exam guidelines for diabetes 2,3,4:

Women who develop gestational diabetes dont usually need an eye exam because they dont develop diabetic eye disease during pregnancy. If you have any questions, ask your doctor.

Your doctor may recommend having eye exams more often than once a year, along with management of your diabetes. This means managing your diabetes ABCs, which include your A1c, blood pressure, and cholesterol; and quitting smoking. Ask your health care team what you can do to reach your goals.

Doctors may treat advanced eye problems with medicine, laser treatments, surgery, or a combination of these options.

Your doctor may treat your eyes with anti-VEGF medicine, such as aflibercept, bevacizumab, or ranibizumab. These medicines block the growth of abnormal blood vessels in the eye. Anti-VEGF medicines can also stop fluid leaks, which can help treat diabetic macular edema.

The doctor will inject an anti-VEGF medicine into your eyes during office visits. You'll have several treatments during the first few months, then fewer treatments after you finish the first round of therapy. Your doctor will use medicine to numb your eyes so you dont feel pain. The needle is about the thickness of a human hair.

Anti-VEGF treatments can stop further vision loss and may improve vision in some people.

Laser treatment, also called photocoagulation, creates tiny burns inside the eye with a beam of light. This method treats leaky blood vessels and extra fluid, called edema. Your doctor usually provides this treatment during several office visits, using medicine to numb your eyes. Laser treatment can keep eye disease from getting worse, which is important to prevent vision loss or blindness. But laser treatment is less likely to bring back vision youve already lost compared with anti-VEGF medicines.

There are two types of laser treatment:

Vitrectomy is a surgery to remove the clear gel that fills the center of the eye, called the vitreous gel. The procedure treats problems with severe bleeding or scar tissue caused by proliferative diabetic retinopathy. Scar tissue can force the retina to peel away from the tissue beneath it, like wallpaper peeling away from a wall. A retina that comes completely loose, or detaches, can cause blindness.

During vitrectomy, a clear salt solution is gently pumped into the eye to maintain eye pressure during surgery and to replace the removed vitreous. Vitrectomy is done in a surgery center or hospital with pain medicine.

In a surgery center or hospital visit, your doctor can remove the cloudy lens in your eye, where the cataract has grown, and replace it with an artificial lens. People who have cataract surgery generally have better vision afterward. After your eye heals, you may need a new prescription for your glasses. Your vision following cataract surgery may also depend on treating any damage from diabetic retinopathy or macular edema.

To prevent diabetic eye disease, or to keep it from getting worse, manage your diabetes ABCs: your A1c, blood pressure, and cholesterol; and quit smoking if you smoke. Read more information on how to manage diabetes.

Also, have a dilated eye exam at least once a yearor more often if recommended by your eye care professional. These actions are powerful ways to protect the health of your eyesand can prevent blindness.

The sooner you work to manage your diabetes and other health conditions, the better. And, even if youve struggled in the past to manage your health, taking better care of yourself now can protect your eyes for the future. Its never too late to begin.

Ask your eye care professional to help you find a low vision and rehabilitation clinic. Special eye care professionals can help you manage vision loss that cannot be corrected with glasses, contact lenses, medicine, or surgery. Special devices and training may help you make the most of your remaining vision so that you can continue to be active, enjoy hobbies, visit friends and family members, and live without help from others.

[1] Centers for Disease Control and Prevention. National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States, 2014. Atlanta, GA: U.S. Department of Health and Human Services; 2014.

[2] Diabetic retinopathy preferred practice pattern guidelines. American Academy of Ophthalmology website. https://www.aao.org/preferred-practice-pattern/diabetic-retinopathy-ppp. Updated January 2016. Accessed June 2, 2017.

[3] Fraser CE, DAmico DJ. Diabetic retinopathy: prevention and treatment. UpToDate website. https://www.uptodate.com/contents/diabetic-retinopathy-prevention-and-treatment. September 28, 2016. Accessed June 2, 2017.

[4] American Diabetes Association. Standards of medical care in diabetes2016 abridged for primary care providers. Clinical Diabetes. 2016 Jan;34(1):321.

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Glaucoma: How to defeat this leading cause of blindness before it strikes; treatment, future – Times Now

December 8th, 2021 1:56 am

Glaucoma is one of the leading causes of blindness in the world.  |  Photo Credit: iStock Images

In a world that is witnessing rapid progress in the arena of science and technology, one hopes that researchers can find answers to some of the most vexing medical maladies. Glaucome or Kala Motiya Bindu is one of them. Glaucoma is the second leading cause of blindness in the world.

What is Glaucoma?Glaucoma is a general term used to describe a group of eye disorders that damage the optic nerve. Damage to the delicate optic nerve leads to vision loss. In most cases of Glaucoma, fluid builds up in the front part of the eye -- putting pressure (intraocular pressure (IOP)/eye pressure) on the eye, gradually damaging the optic nerve.

Left untreated, this eye pressure can permanently affect vision. Treatments including eye drops, laser treatments and surgeries can slow down vision loss and save your sight.

What causes Glaucoma?According to Cleveland Clinic, glaucoma can occur without any cause but is affected by many factors. The most important of which is the intraocular eye pressure. Your eyes produce a fluid called aqueous humor that nourishes them. This liquid flows through the pupil to the front of the eye. In a healthy eye, the fluid leaves through a drainage canal located between the iris and cornea.

Is Glaucoma curable? If not now, maybe in the near future?At the moment we have no treatment that can restore the lost vision. We will need to insert new nerve cells, reconnect the new cells to the cells that are still there, and make those connections work with the existing connections in the way that they did originally. Doctors and researchers across the world have taken the first steps in this process, it will be years before the successful restoration of vision in a human eye is possible

Why is glaucoma not caught early?One of the reasons that glaucomas damage is not noticed early on is that it typically affects only one eye at first. The other eye is still fully functional. Since the brain converts the two separate signals from both eyes into a single picture, we see it and we think nothing is missing. Until of course, too late.

Can glaucoma affect both eyes?Most people develop glaucoma in both eyes, although the disease initially may be worse in one eye. Certain types of glaucoma appear to cause moderate or severe damage in one eye initially, while the other eye may be mildly affected. Over time, the disease damages both eyes. People with closed-angle glaucoma in one eye have a raised likelihood of developing the same type of glaucoma in the other eye within five to 10 years.

Which hospitals are the finest in glaucoma treatment?According to the Global Clinic Rating (GCR) website, the Wilmer Eye Institute at the Johns Hopkins Hospital, the Cleveland Clinic's Cole Eye Institute, the Jules Stein Eye Institute, and the Ahad Mahootchi, MD, PA are the four top-most among the best all-around ophthalmology centres in the United States. These are also top-ranked clinics for glaucoma treatment. ()

Indian-origin Dr Pradeep Ramulu, MD, PhD is the Chief of the Glaucoma Division at the Johns Hopkins -- Wilmer Eye Institute.

How to prevent glaucoma:Early detection of glaucoma through routine eye exams is the best way to protect eye health and prevent vision loss. Make sure that you have eye health checkups periodically, just as one sets the calendar for a dental check-up and other health issues. Cleveland Clinic suggests that you must visit your ophthalmologist as per the table suggested below:

Disclaimer: Tips and suggestions mentioned in the article are for general information purpose only and should not be construed as professional medical advice. Always consult your doctor or a dietician before starting any fitness programme or making any changes to your diet.

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UVA Discovers Harmful Inflammation Trigger in Lupus, Macular Degeneration | UVA Today – University of Virginia

December 8th, 2021 1:56 am

University of Virginia School of Medicine researchers have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness.

The two diseases share a common contributor to harmful inflammation, the scientists found. The insights could let researchers develop new treatments for those diseases and other conditions driven by the newly discovered inflammation source.

We were quite surprised at the common link between lupus and macular degeneration, said Dr. Jayakrishna Ambati of UVAs Department of Ophthalmology and the founding director of UVAs Center for Advanced Vision Science. It appears that the new inflammatory pathway we identified could be therapeutically targeted for many chronic diseases.

Ambati and his collaborators have discovered an unknown role for an inflammasome an agent of the immune system called NLRC4-NLRP3. Inflammasomes play an important role in marshaling the bodys defenses to protect it from invaders such as viruses and bacteria.

In lupus and atrophic macular degeneration, however, it appears that NLRC4-NLRP3 contributes to harmful inflammation, the UVA researchers found. In lupus, it helps drive the hyperactive immune response that leads to symptoms such as joint pain, rash, fever and more. In macular degeneration, meanwhile, NRC4-NLRP3 appears to contribute to inflammation that destroys the vital light-sensing cells in the eyes retina.

Ambatis new work helps explain why. The inflammasome, he found, is sent into action by a special class of genetic material calledshort interspersed nuclear element RNAs,or SINE RNAs. This type of RNA makes up more than 10% of our genomes, and it activates in response to cell stresses such as infection, genetic damage and aging. The resulting inflammation caused by SINE RNAs can be harmful in many chronic diseases.

SINE RNAs are elevated in both macular degeneration and lupus, Ambati found. In addition to discovering the role of SINE RNA in the two diseases, Ambati and his colleagues identified an unknown receptor for the SINE RNAs called DDX17. Scientists have been looking for this receptor for decades, and the new discovery helps them better understand the process that leads to the harmful inflammation.

These findings indicate that blocking a single inflammasome might not be enough, and that targeting both the NLRC4 and NLRP3 inflammasomes would be a superior strategy, Ambati said.

Using this new information, scientists may be able to target the source of harmful inflammation in lupus, macular degeneration and other diseases driven by SINE RNAs. That could lead to new treatments to benefit patients, the UVA researchers say.

Were excited to have developed drugs called Kamuvudines that block this dual inflammasome, which we anticipate will be in clinical trials next year, Ambati said.

The researchershavepublished their findings in the scientific journal Science Immunology. The work is featured on the journals cover. The research team consisted of Shao-bin Wang, Siddharth Narendran, Shuichiro Hirahara, Akhil Varshney, Felipe Pereira, Ivana Apicella, Meenakshi Ambati, Vidya L. Ambati, Praveen Yerramothu, Kameshwari Ambati, Yosuke Nagasaka, Dionne Argyle, Peirong Huang, Kirstie L. Baker,Kenneth M. Marion, Kartik Gupta, Bo Liu, David R. Hinton,Scott W.Canna, Tamer Sallam, Srinivas R. Sadda, Nagaraj Kerur, Bradley D. Gelfand and Jayakrishna Ambati.

Jayakrishna Ambati is a co-founder of iVeena Holdings, iVeena Delivery Systems and Inflammasome Therapeutics and has done consulting work unrelated to the research. A full list of the authors disclosures is included in the paper.

The study was supported by the National Institutes of Health, grantsDP1GM114862, R01EY028027, R01EY29799, R01EY031039, R01AI148741, R00EY024336, R21EY030651, R01EY028027, R01EY031039 and R01EY032512. It was also supported by the John Templeton Foundation, grant 60763; the UVA Strategic Investment Fund; the DuPont Guerry III professorship; a gift from Mr. and Mrs. Eli W. Tullis; the BrightFocus Foundation; and the Owens Family Foundation.

To keep up with the latest medical research news from UVA, subscribe to theMaking of Medicineblog.

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The many benefits of Vitamin A – Deccan Herald

December 8th, 2021 1:56 am

Ever been told to properly eat your carrots and spinach because theyre good for your eyes? If yes, chances are you are familiar with the many benefits of the wonder nutrient - Vitamin A. Abundantly available in carrots, tomatoes, bell peppers, and broccoli, Vitamin A is required by the human body for normal functioning. Its deficiency can also cause a range of problems ranging from vision, immune function, reproduction and skin health.

Benefits of Vitamin A

Vitamin A helps vital organs like the heart, kidneys, and lungs function optimally. When it comes to eyes, it helps them adjust to dim light conditions. Its benefits are more easily understood if one knows what insufficient Vitamin A could translate to, health-wise. A mild vitamin A deficiency could be behind dry skin, fatigue, vulnerability to infections, and even infertility. If one is seriously deficient in this essential micronutrient, they could majorly undermine eye health, and experience issues such as severe eye dryness, night blindness and irregular patches on the white of the eyes. According to the World Health Organisation, Vitamin A deficiency contributes to maternal mortality and other poor outcomes of pregnancy and lactation. Insufficient Vitamin A diminishes the ability to fight infections.

What does Vitamin A help with?

Better overalleye health

Lessening the risk of blindness, including night blindness, and vision loss due to macular degeneration

Development of immune cells and strengthen bodys ability to fight infections

Supporting a healthy pregnancy and fetal growth

Treating acne and supporting skin health, to some extent

Reducing the risk of some types of cancers, such as lung and prostate cancers

Sources of Vitamin A

As a rule of thumb, no matter the health goal, a balanced diet plan should factor in all nutrients according to the daily requirement of the specific micronutrient. Coming from both animal sources (called retinoids and including retinol) and plant sources (called carotenoids and including beta-carotene), Vitamin A is formed within the human body by the conversion of beta-carotene into vitamin A.

The provitamin Vitamin A can be naturally obtained from green leafy vegetables like broccoli and spinach, bright-coloured vegetables like sweet potatoes, pumpkin, carrots and squash, as well as bell peppers, tomatoes, apricots, mangoes, and dairy products like milk. It is also found in certain kinds of cheese.

One can also find a type of this vitamin, called preformed Vitamin A, from meat, poultry, fish, and dairy products. If you are keeping your meals balanced, theres a strong possibility that you are meeting the recommended daily allowance (RDA) of Vitamin A which is about 600 micrograms for both men and women.

These limits, however, have recently been revised by the Food Safety and Standards Authority of India (FSSAI) to about 1000 micrograms for men and 840 micrograms for women, applicable from 2023. In addition to filling up your plate with healthier food choices, one way of upping your daily Vitamin A intake could be oral supplements. However, one must be aware of the amount of every micronutrient going inside the body, so it does not cause exceed the tolerable upper level (UL) intake.

(The writer is a nutrition specialist)

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Saudi aid agency drive to combat blindness in Djibouti ends – Arab News

December 8th, 2021 1:56 am

JEDDAH: With more than 130 films set to be screened at the Red Sea International Film Festival, VOX Cinemas are on a mission to support and promote local films the best way they can.

The Red Sea International Film Festival kicked off its festivities at Jeddahs UNESCO World Heritage Site old town, Al-Balad, on Dec. 6. It will run until Dec. 15, in partnership with VOX Cinemas and others.

VOX Cinemas will screen 138 feature films and shorts from 67 countries in 34 languages. The content was produced by established and emerging talent, with fans, film enthusiasts, filmmakers and actors in attendance for many of the films.

A slate of new Saudi films 27 from an exciting wave of Saudi filmmakers will be shown alongside the best of contemporary international cinema.

Were very proud to be partners of this festival, especially since this has been the first international Red Sea Film Festival taking place in Jeddah in the Kingdom of Saudi Arabia, Toni El Massih, managing director of VOX Cinemas, told Arab News.

RSIFF is a significant breakthrough for the whole industry, exhibitors, distributors and producers, he said. This platform will help future filmmakers and storytellers know that this country is so full and rich in culture and storytelling. This is the exact platform that is needed for the talent to come across and present their project, he added.

HIGHLIGHT

VOX Cinemas will screen 138 feature films and shorts from 67 countries in 34 languages. The content was produced by established and emerging talent, with fans, film enthusiasts, filmmakers and actors in attendance for many of the films.

On tour to the main VOX Cinema sites in Al-Balad that have been constructed to screen RSIFF films, Arab News spoke to Mohamed Al-Hashemi, KSA chief of Majid Al Futtaim. He said: The Red Sea Film Festival is a statement for the Kingdom. There were no cinemas prior to April 2018, however, customers enjoyed the set of experiences as soon as they opened.

With life coming back to normal after the COVID-19 period, the Red Sea Film Festival is a statement from the Kingdom to the world that Saudi Arabia will be a major player when it comes to local content production, demand for international content, and most importantly, demand for exhibitions as well, when it comes to the best of the best that can be offered to consumers.

With movie theaters in more than six cities across the Kingdom in over 15 locations, VOX Cinemas operates 154 screens in Saudi Arabia. We are considered to be the largest cinema exhibitors in the Kingdom in terms of site numbers and screen counts, Al-Hashemi said.

Why is the screen count so important?

The screen basically is the only platform where people can showcase local content producers on the big screen. With more big screens, more local content will be produced for the local market and the regional market, and hopefully Saudi as well to the international market, Al-Hashemi said.

The RSIFF is where the Kingdom can act as a local content producer and where we can bring out the folded and untold stories of this beautiful company, to the customers within Saudi, he added.

On Dec. 6. during the inaugural red-carpet event, VOX Cinemas announced an ambitious initiative that aims to foster homegrown talent and showcase untold stories on the big screen.

A plan was made to boost regional film production and develop 25 Arabic films in the next five years.

El Massih said that many of these films would be from Saudi Arabia, with Saudi talent working as directors, producers and actors. There will also be films coming out of the United Arab Emirates and Egypt.

Speaking on the genres of the future films, he said: The genre that we are focusing on and that has proven to work best is the comedy-drama. This is the sort of film that well be working toward.

As part of the initiative, VOX Cinemas will continue to support the next generation of homegrown content developers and provide resources for emerging filmmakers to bring their scripts to screen.

This platform will search and scout for talent. Itll be the same case later in the UAE and in other festivals that are taking place across the region.

Accordingly, well start putting a team together, building screening and writing rooms, getting stories from each of the different regions together, and then well take that forward and then do the necessary films that well see on the big screen, El Massih said.

Majid Al Futtaim has been very active in the region since 1999, starting off with exhibition, and then elevating our activities into film distribution, and recently in film production.

Being a main contributor and partner of RSIFF is huge, he added, saying that such an opportunity will support emerging talent.

El Massih said: This is the perfect platform for us to be participating and searching for the emerging talent and filmmakers that we can bring on board.

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Air Pollution Causes Irreversible Damage to The Eyes – India.com

December 8th, 2021 1:56 am

With AQI values in the majority of Indias major cities reaching dangerously high levels, it is taking a big toll on our eyes, posing a significant risk to our eye health and eyesight in general. Air pollution has been linked to an increased risk of age-related macular degeneration (AMD), a progressive and irreversible visual loss that can lead to blindness.Also Read - Air Pollution Latest Update: Air Quality Panel Orders Immediate Closure of Industries in NCR For Not Using Cleaner Fuels

AMD is the major cause of permanent blindness among those over the age of 50 in high-income nations, with 300 million people expected to be afflicted by 2040. Also Read - Can Air Pollution Cause Vision Loss? Expert Answers

Certain people, such as elderly patients, smokers, Covid patients, and people with heart and lung problems, are especially vulnerable to high amounts of pollution. Also Read - Delhi Metro Presses 14 Anti-Smog Guns Into Service at Project Sites to Curb Air Pollution, to Install More

Individuals who travel in highly polluted areas, as well as those who stay outside for a lengthy amount of time, are equally at risk.

Fine ambient particulate matter with an aerodynamic diameter of 2.5 micrometres, nitrogen dioxide, and sulphur dioxide are all associated with an increased risk of self-reported age-related macular degeneration (AMD).

Air pollution is a global issue that many people cannot avoid, with the World Health Organization (WHO) claiming that more than 99 per cent of the worlds population lives in areas where air quality levels exceed the limits established for chemicals that pose health concerns.

Dry Eye Disease, watering and burning sensations, impaired vision, cataracts, irritation, allergies, and even glaucoma are some of the symptoms that are commonly noticed following ocular exposure to air pollution.

While long-term solutions are required to reduce air pollution, eye specialists feel that some preventive actions, such as wearing sunglasses and limiting eye contact with airborne contaminants, can assist. Artificial tears and eye drops can help lubricate the eyes and keep irritation at bay.

In the absence of an infection or allergy, the treatment for the ocular symptoms of air pollution exposure is simply to cool the eyes by using a cold compress.

Cosmetics and contact lenses should be avoided in the event of pain until the eyes have totally recovered. If any symptoms continue, a complete eye examination should be undertaken to determine the underlying reason.

In addition, one must also practise preventive maintenance by seeing an eye doctor on a regular basis, which can help reduce the likelihood of getting an eye ailment. Furthermore, having a diet rich in important vitamins and minerals, staying healthy, quitting smoking, and maintaining hand cleanliness will aid in taking early precautions.

(Authored by Dr Hem Shah , Senior Consultant, Sharp Sight Eye Hospitals)

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Pope at Mass in Cyprus: Only together can we be healed from blinding darkness – Vatican News

December 8th, 2021 1:56 am

Pope Francis refers to the parable of the two blind men from Matthew's Gospel to urge Cypriots to follow three steps in order to be freed of a similar darkness in which we often find ourselves.

By Francesca Merlo

Addressing the faithful in Nicosia's GSP Stadium for Holy Mass in Cyprus, Pope Francis recalled a passage from Matthew's Gospel, in which as Jesus passed by, two blind men cried out "Have mercy on us, Son of David". The Pope noted that the two men are blind, yet they realise that Jesus is the Messiah who has come into the world. They can help us, during this advent season, "to welcome the Lord when he comes", said the Pope.

Pope Francis noted that the first step is that the two "went to Jesus for healing". Although they cannot see him, he said, "they hear his voice and follow his footsteps".The two men in the Gospel trusted in Jesus, he continued, and so "they followed him in search of light for their eyes".

The Pope noted that the two trusted in Jesus because "they realise that, within the darkness of history, he is the light that brightens the nights of the heart and the world". He stressed that we too have a kind of blindness in our hearts, and like the two blind men are often immersed in the darkness of life.Often we would rather remain closed in on ourselves, alone in the darkness, feeling sorry for ourselves and content to have sadness as our companion, but instead we must go to Jesus, said the Pope. Let us give Jesus the chance to heal our hearts.

The next step, continued the Pope, is that "they shared their pain".They ask for help together, said the Pope. "This is an eloquent sign of the Christian life and the distinctive trait of the ecclesial spirit: to think, to speak and to act as we, renouncing the individualism and the sense of self-sufficiency that infect the heart".

These two blind men have much to teach us, continued the Pope. "Each of us is blind in some way as a result of sin", he explained, adding that this "prevents us from seeing God as our Father and one another as brothers and sisters". This sin distorts reality, continued the Pope, but if we bear our inner blindness alone, we can become overwhelmed. "We need to stand beside one another, to share our pain and to face the road ahead together", he said.

Dear brothers and sisters, continued the Pope. "Faced with our own inner darkness and the challenges before us in the Church and in society, we are called to renew our sense of fraternity". If we remain divided we will never be completely healed of our blindness", he stressed. Healing takes place when we carry our pain together, when we face our problems together, when we listen and speak to one another.

The third, and final step, continued the Pope, is "they joyfully proclaimed the Good News". After Jesus had healed the two blind men, the two "began to spread the good news to the entire region". There is a bit of irony in this, noted the Pope. "Jesus had told them to tell no one what had happened, yet they do exactly the opposite". Their intention was not to disobey the Lord, said the Pope. "They were simply unable to contain their excitement at their healing and the joy of their encounter with Jesus". This, he added, "is another distinctive sign of the Christian".

Bringing his homily to an end, the Pope thanked all thos present in the Nicosia stadium for living "with joy" the liberating message of the Gospel, and encouraged them to "keep advancing on this path". Like the two blind men in the Gospel, "let us once more encounter Jesus, and come out of ourselves to be fearless witnesses of Jesus to all whom we meet!"

"Brothers and sisters, the Lord Jesus is also passing through the streets of Cyprus, hearing the cries of our blindness", stressed the Pope. "He wants to touch our eyes and hearts and to lead us to the light, to give us spiritual rebirth and new strength".Let us renew our faith in him, concluded the Pope, "Let us say to him: Jesus, we believe that your light is greater than our darkness; we believe that you can heal us, that you can renew our fellowship, that you can increase our joy".

Full video of Holy Mass at the GSP Stadium" in Nicosia, Cyprus

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Amid the Conflict in Yemen, Mass Campaigns to End the Threat of Tropical Diseases Continue [EN/AR] – Yemen – ReliefWeb

December 8th, 2021 1:56 am

Schistosomiasis and soil-transmitted helminths are neglected tropical diseases (NTDs), but these parasitic worm infections can lead to anemia, malnutrition, and learning difficulties among children. Left untreated, schistosomiasis can damage the liver, intestines, bladder, spleen, and lungs, and soil-transmitted helminths can cause a range of problems, including slow physical and mental development.

Public health authorities have battled for more than a decade to tackle schistosomiasis, supported by partners such as the World Banks International Development Association (IDA) and World Health Organization (WHO). In 2010, one in five residents in Yemen were at risk of contracting schistosomiasis, better known as bilharzia. Today, that has dropped to fewer than one in 15 (about three million people). Limited data exists for the soil-transmitted helminths that affect communities across the country but bringing these infections under control is another public health goal.

Eliminating schistosomiasis involves the mass administration of drugs, in which members of a target population are treated once a year. Several rounds of drugs are administered over several years to get rid of a community of the parasite. The Emergency Health and Nutrition Project (EHNP), funded by IDA, the World Banks fund for poorest countries, has helped to eliminate schistosomiasis as a public health problem in Yemen.

Nothing beats a childs smile. This project represents a critical opportunity to decrease the disease burden among vulnerable Yemenis, particularly children. The project is part of the World Banks strategy to invest in Yemens most important assets: its people said Tania Meyer, World Bank Country Manager for Yemen.

During a recent four-day mass campaign, almost 860,000 children and adolescents between 6- and 19-years-old, were targeted (whether enrolled in school or not) across seven southern and eastern governorates, Abyan, Hadramout/Mukalla, Hadramout/Sayoun, Lahj, Mareb, Shabwa, and Taiz. In total, 37 districts, 373 team leaders, 1,070 team supervisors, and 2,140 drug distributors were involved and over 80% of the target population reached.

Yemen is making progress against other neglected tropical diseases as well. Lymphatic filariasis, which causes swelling of limbs and is spread by infected mosquitos, was eliminated as a public health problem in 2019. The administrative certification of the elimination of leprosy in Yemen is underway, and technical teams are working hard to eliminate blindness of infectious origins: trachoma by 2024, and onchocerciasis, or river blindness, by 2030.

This progress is encouraging, and a sign that the elimination of schistosomiasis as a public health problem may be within reach in Yemen in the next five years, said Dr. Adham Rashad Ismail Abdel-Moneim, WHOs Yemen Representative. Reaching it, however, will depend on continued support from partners.

The campaign was carried out in close collaboration with Yemens Ministry of Education and th Health Education Center, which is part of the Ministry of Public Health and Population. Technical and statistical local plans were prepared, a training of trainers session carried out, and workshops given to drug distributors and the heads of teams in charge of both fixed and mobile treatment facilities. A third-party team conducted direct monitoring of the activities and interviews with around 4,000 people across 1,000 randomly selected households.

The campaign in January 2021 targeted 2.4 million people at 3,300 sites across 32 districts in seven northern governorates, involving 6,700 drug distributors. Approximately, 4.8 million praziquantel tablets and 2.4 million albendazole tablets were distributed.

More mass campaigns against soil-transmitted helminths and schistosomiasis are planned in 2022, with more investment to improve community engagement made in order to reach more than 80% of the targeted population in future.

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Defence policy is based on ‘over-simplified’ hype about cyber warfare, experts warn – Telegraph.co.uk

December 8th, 2021 1:56 am

Britain's defence policy is based on "over-simplified" hype about cyber warfare, experts have claimed in a new book.

Defence experts Dr Jack Watling and Justin Bronk say damaging narratives are too easily accepted as fact by many in military and government circles.

Such assumptions quickly come to dominate thinking at the highest levels of UK defence policy, they have said.

In a new book launched on Monday, called Necessary Heresies, the experts warn there is an institutional blindness at the heart of UK defence policy.

Specialist advice is often overlooked or misinterpreted as senior decision-makers shape policy based on their own understanding, the book argues, of briefings given by subject matter experts.

Crucial nuances and practical constraints are almost unavoidably lost in translation.

This tendency is exacerbated by a natural inclination to over-hype the potential for novel technologies or strategies to provide transformative effects.

The authors argue future war is unlikely to be dominated by grey zone attacks short of out and out armed conflict.

The dangers of so-called grey zone operations, characterised by cyber attacks, assassinations, political interference and disinformation, were regularly cited by the former Chief of the Defence Staff (CDS), General Sir Nick Carter, as being the likely shape of future warfare.

The authors say such woolly thinking is an intellectual dustbin that confuses the true nature of conflict.

They cited Gen Carters comments during the annual CDS Rusi lecture, delivered in December 2020, that our rivals seek to win without resorting to war.

He said that arms length tools like drones and mercenaries would be used more often as they provide deniability and strategic ambiguity - thus enabling intervention without the risk of entanglement.

The authors say Gen Carters ideas not only lack crucial nuance and are unsound, but also produce "potentially harmful distortionary effects throughout Defence.

The new book attempts to challenge some of these misleading narratives before they drive acquisition and force-design decisions that undermine the British Armed Forces.

The book argues that through years of repetition, narratives about the rapidly changing character of warfare and the transformative effects of novel technologies have become akin to gospel truths, enshrined in policy documents.

Senior defence policy planning is hampered by received wisdom the authors suggest.

In many areas of Defence policy, such as cyber warfare, space or novel weapons systems, deep subject matter expertise is required to understand the potential benefits and limitations."

Incompatible demands for efficiency savings and equipment modernisation lead to senior defence planners seeking silver bullet solutions.

Once policy has been stated on an issue, further nuances and important caveats are often lost as the wider policy community try to tailor their own outputs to align with what they perceive as the new high-level consensus.

As such, the narratives that end up shaping much of the coal face work in Defence are not...(usually) nuanced.

Instead, they are often mantras or collective received wisdom that in practice has been oversimplified or distorted by repeated translation, repetition, and transmission.

A Ministry of Defence spokesperson said: With 24 billion investment over the next four years, the Armed Forces will be modernised to meet future threats. The Integrated Review, backed by the largest investment in Defence since the Cold War, is delivering a force fit to meet the challenges posed by a more uncertain world, not battles of the past.

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In search of ‘colour’: The story of aspiring filmmaker Ashutosh Kumar’s tryst with FTII – EdexLive

December 8th, 2021 1:56 am

When did you finally realise what you'd do in life? Some of us are still clueless. But Ashutosh Kumar (30), from Patna had not only decided which career to take up but also selected an institute for himself when he was in Class 7. He wanted to work with films and graduate from the Film and Television Institute of India (FTII) in Pune. But what he did not know is that his dreams would have to jump through hoops for at least 6 years to get there.

And it all came down to a filmmaker's essence - his eyes. Ashutosh found out that he was colour blind at the medical examination before his admission to the FTII and that changed his life. "I was intrigued by cinema from a very young age. Both our parents would go to work and my sister and I would spend the afternoons watching films. When I was in Class 7 or so, I accompanied my father to Delhi. On our way back, we met two people who claimed to be filmmakers and were talking about films. I heard the name FTII for the first time and studying there became a goal. After I finished my schooling I wanted to enrol, but they (FTII) said that I needed a graduation degree to get in. I did my graduation completed my graduation in BA Psychology (Hons) from Patna University. The next step was to apply. I applied in 2013 the first time but did not get in. In 2016, I got through Film Editing. I was there prepared with the fees and everything. Then came the test, where they said that I was colour blind and that I was not eligible to study this course," said Ashutosh.

READ ALSO :FTII students desperately reach out to Shekhar Kapur in a bid to stop online classes, but to no avail

Ashutosh moved the Bombay High Court and then the Supreme Court in 2017. In the meanwhile, he has been taking up freelance work after a short stint in journalism and also completed his Masters in Mass Communication from the Nalanda Open University. "I have endured everything in these few years. I do not come from a family with affluence or filmmakers in their lineage," said Ashutosh. He also reached out to famous filmmakers like Raju Hirani for their statement on this issue and they helped. "Colour blindness should not affect the work of a film editor," wrote Hirani and added that the director and the cinematographer are the people who look after that aspect.

Ashutosh said that his fight was not just for himself but for everyone with colour blindness. "Three out of 10 human males in the world are colour blind. This isn't just my fight but for all those who will come next," said the young filmmaker.

The Supreme Court bench of justices Sanjay Kishan Kaul and MM Sundresh has now asked a committee to be formed. The committee will have an ophthalmologist, director, film editor, colourist, script supervisor, head of any department of FTII and a lawyer. Role of the committee would be to ascertain whether colour blindness is to be perceived as a disqualification for all courses in FTII, the court order said, adding that the rules of the institute need to be looked at keeping the Right to Persons with Disabilities (RPwD) Act of 2016 in the perspective. It is an evolving process. We now have documents with details of some renowned filmmakers, some even got national awards in India, who have been colour blind...The best thing to say is that with the advancement of science, the issue should be revisited by a committee, within the principle of reasonable accommodation. It is futuristic thinking, added the two-judge bench.

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In search of 'colour': The story of aspiring filmmaker Ashutosh Kumar's tryst with FTII - EdexLive

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"Sight"-restoring bionic eye proceeds along the path to human trials – New Atlas

December 8th, 2021 1:56 am

There may be new hope for people with certain types of blindness, as an experimental sight-restoring device has been deemed safe for implantation. It still has to be tested on humans, though, and it will likely provide a fairly rudimentary form of vision.

Known as the Phoenix99 Bionic Eye, the prosthesis is currently being developed by scientists at Australia's University of Sydney and University of New South Wales. It's intended for use on patients with blindness caused by degenerative conditions such as retinitis pigmentosa, in which the retina is compromised but the optic nerve remains intact.

The system incorporates a small video camera mounted on a pair of glasses, which images the scene in front of the wearer. Its output is converted into a wireless signal, which is transmitted from the camera to a communication module implanted under the skin behind the patient's ear.

That module in turn decodes the video signal into a pattern of electrical pulses, which are relayed to a stimulation module which is implanted on the retina in the affected eye(s). That device is able to bypass the retina's dysfunctional photoreceptor neurons, which have lost their ability to react to light focused onto the retina. Instead, the implant directly stimulates the underlying (and still functional) retinal ganglion cells, which are responsible for gathering input from other retinal cells and relaying it along the optic nerve to the brain.

"With regards to the quality of the restored vision, we know that it will be very different from what one would call normal vision," U Sydney biomedical engineer Samuel Eggenberger tells us. "Similar concepts of electrical stimulation of the retina have been tested in humans around the world and the results have been very variable, but expectations should be that the prosthesis will provide simple information about the persons surroundings such as detecting obstacles, with the purpose to help with navigation, orientation or even reading of big letters."

In a recent three-month study, it was found that the Phoenix99 setup was well-tolerated by the bodies of sheep in which it was implanted. There were no reactions in the tissue surrounding the components, leading the scientists to believe that the system could safely remain in place for a number of years. The team is now applying for approval to conduct clinical trials on humans.

"We hope that through this technology, people living with profound vision loss from degenerative retinal disorders may be able to regain a useful sense of vision," says Eggenberger.

A paper on the sheep study was recently published in the journal Biomaterials.

Source: University of Sydney

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Disease Interventions Give Health Systems a Boost – SaportaReport

December 8th, 2021 1:56 am

By Dr. Kashef Ijaz, Vice President-Health, The Carter Center,and Sarah Yoss, Associate Director of Special Health Projects, The Carter Center

When The Carter Center partners with a country to eliminate a disease through its disease-specific programs or otherwise improve health, a related goal is to strengthen the overall health system of the partner country. Strengthening health systems aligns with the Carter Centers core belief that people can improve their own lives when provided with the necessary skills, knowledge, and access to resources.

The Centers Public Health Training Initiative has helped improve the preparedness of health professionals in Ethiopia, Nigeria, and Sudan, while our Mental Health Program has assisted in the building of a mental health care system in Liberia by supporting the training of hundreds of clinicians. Even beyond those focused initiatives, there is an element of health systems strengthening in all of our disease-specific health programs Guinea worm eradication, river blindness elimination, trachoma control, lymphatic filariasis elimination, schistosomiasis control, and our efforts to eliminate malaria and lymphatic filariasis from Hispaniola. Each of our health programs work closely with ministries of health and local communities to strengthen public health capabilities and improve health services.

Health systems strengthening, as defined by the World Health Organization, consists of efforts to achieve sustained improvements in health outcomes through the improvement of the six building blocks of a health system:

Health systems strengthening is also key in promoting global health security, as has been apparent throughout the COVID-19 pandemic as well as previous events such as the Zika virus outbreak in Latin America and the Ebola outbreak in West Africa. Increasingly, national and global public health organizations, including the WHO, are framing health systems strengthening as integral to health security, promoting an approach that can build and maintain essential health services alongside the resources and capacities to prevent, detect, and respond to health emergencies, including epidemics and pandemics.

This concept was summed up by Dr. Tedros Ghebreyesus, director-general of the WHO: Quality health systems not only improve health outcomes in peacetime, theyre also a bulwark against outbreaks and other public health emergencies. Universal health coverage and health security are two sides of the same coin.

The Carter Centers efforts focus on strengthening the capabilities, processes, and resources of ministries of health, national public health institutes , health training programs in academic institutions, the primary health care system, and community-based health workers, so that countries and communities will be equipped to stand on their own with robust domestic systems and will not have to rely on outside assistance.

Health systems strengthening promotes health security within the particular country and around the world by improving the countrys ability to identify and mitigate future outbreaks before they become pandemics. That alone should be incentive enough to support the effort.

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New LED headlights are blinding drivers. Will it take tragedy to fix it? – Desert Sun

December 8th, 2021 1:55 am

Brian Davis| Guest columnist

Bright headlights and super bright tail lights.

I'm talking about these new cars with the LED lights where it seems that they have their brights on. In some cases they actually do.

These lights are a danger because they're blinding. After the car passes you, your eyes are affected.

I know I'm not alone on this, because I talk to many people. There are multiple Facebook groups about this.There are multiple articles written about this.

There are also petitions that are being signed.

As always, it takes people with money and influence to die from an issue before anything is done.

So my rhetorical question is: When will the right people with money and influence die from a car accident due to night blindness because of the super bright LED lights on some vehicles?

In the meantime, I'm encouraging people to adjust their visors with all kinds of shading devices to block thelights from many cars.

The problem with this is decreases your lead time on seeing a pedestrian or a bicyclist or perhaps another car coming out in front of you.

I can't imagine the supposed safety factor of these super-blinding LED lights outweighs people being blinded by them or blocking their vision with visors.

Super bright LED brake lights on some of these vehicles are equally as dangerous, particularly when sitting behind them at a red light.

I know I'm not alone in this, because I talk to other people who experience the same thing.

The National Highway Traffic Safety Administration has really missed the ball with allowing these vehicles to be manufactured and sold in the United States.

There's also the issue of people retrofitting their old headlight lenses with LEDs that end up being just as blinding, if not worse.

My question is what is being done by elected officials or bureaucrats about this? And why are police not citing these vehicles right and left for inspections?

Brian Davis lives inCathedral City.

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Religious Groups Official Positions on Stem Cell Research …

December 8th, 2021 1:54 am

American Baptist Churches in the U.S.A.

The group has no explicit policy on the issue; rather it states that one must be guided by ones own relationship with God and Scripture.

Overview: Stem Cell Research at the Crossroads of Religion and PoliticsEmbryonic stem cell research, which uses cells found in three- to five-day-old human embryos to seek cures for a host of chronic diseases, has sparked a major debate in the United States.

The Science Behind Stem Cell ResearchStem cells, the building blocks of nature, can transform into any other type of cell in the body.

Public OpinionA March 2009 poll report from the Pew Research Center for the People & the Press finds that opinions about stem cell research have been fairly stable in recent years.

Religious Groups Official Positions on Stem Cell ResearchA breakdown of 17 major religious groups views on the issue.

Stem Cell Research Around the WorldThe U.S. is only one of many countries playing an important role in stem cell research.

Quotes on Stem Cell ResearchQuotes on stem cell research from political, religious and other prominent figures.

Though Buddhist teachings do not directly address the issue, there are two main tenets the prohibition against harming or destroying others (ahimsa), and the pursuit of knowledge (praja) and compassion (karua) that divide Buddhist scholars and communities. Some Buddhists argue that stem cell research is in accordance with the Buddhist tenet of seeking knowledge and ending human suffering, while others argue that it is a violation of the notion of not harming others.

In accordance with their anti-abortion stance, the U.S. Conference of Catholic Bishops supports adult stem cell research but opposes embryonic stem cell research since it creates or destroys human embryos.

The Church of Jesus Christ of Latter-day Saints has not issued a statement on the issue of stem cell research.

In 2004, the churchs governing body, the General Convention, declared itself in favor of stem cell research as long as the embryos used would have been destroyed otherwise, the embryos were not created solely for research purposes and the embryos were not bought or sold.

The ELCA does not have an official position on the issue. In 2005, the Churchwide Assembly, the governing body of the church, created a task force to study the issues of genetics and biotechnology and to present a report in 2011.

Though Hinduism believes that life begins at conception, the religion has no official position on stem cell research.

There is no explicit Islamic ruling on the issue of stem cell research. While some Muslim leaders allow for stem cell research on the ground that, according to Islam, an embryo in the early stage of pregnancy does not have a soul, others argue that the termination of an embryo at any stage of pregnancy is morally impermissible.

All major Jewish denominations including the Reform, Conservative, Orthodox and Reconstructionist movements support both embryonic and adult stem cell research as long as it is for medical or therapeutic purposes.

In 2005, the group reaffirmed its opposition to embryonic stem cell research, advocating instead for adult stem cell research.

In 2005, the National Association of Evangelicals issued a statement voicing its opposition to stem cell research.

After an evaluation in 2006 of the debate surrounding stem cell research, the National Council of Churches Human Biotechnologies Policy Development Committee adopted a position stating that as a result of a lack of clear consensus [among ethicists, academia and scientists], the National Council of Churches neither endorses nor condemns experimentation on human embryos.

In 2004, the Presbyterian Churchs governing body, the General Assembly, reaffirmed its position in favor of stem cell research that is intended to [restore health] to those suffering from serious illness.

In 1999, the Southern Baptist Convention reaffirmed its opposition to the destruction of human embryos [and] support for the development of alternative treatments which do not require human embryos to be killed.

In 2006, the associations policymaking body, the General Assembly, stated its support for stem cell research as long as the research is for medical therapies and not the reproductive cloning of humans.

In 2001, the United Church of Christ ruled in favor of research on embryonic stem cells that would otherwise be discarded from in vitro fertilization.

In 2004, the United Methodist Church asserted its support for therapeutic cloning in which spare embryonic stem cells resulting from in vitro fertilization are used. The church also maintained its opposition to the use or creation of embryonic stem cells solely for the purpose of research.

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Regenerative Stem Cells Knee Pain Treatment London, UK …

December 8th, 2021 1:54 am

The Regenerative therapy procedure is performed in an outpatient setting and only takes up to two hours. No general anaesthesia is required, and most patients dont need post-operative pain medication. After the procedure, patients typically return to work within a week or two and may resume physical activity much faster than after invasive surgery. Many patients report feeling marked improvement in their joint within one to three months.

For the procedure, PRP and cell concentrates are obtained from your body and prepared for injection. Once injected, cells follow inflammatory signals from damaged tissues and travel to the injured areas. These cells have multiple ways of repairing these damaged areas from inducing the production of natural anti-inflammatories which can assist with Osteoarthritis pain and swelling in the joint area to kick-starting the healing in injuries and stimulating regeneration. The anti-inflammatory effect lasts from 2-3 months. From there, you can see continued gradual improvement as the cells help provide healing to the affected area. However, you should not expect to see the full effect of the treatment earlier than six months, especially in the case of joint interventions. Variables like the type of disease or condition, age, lifestyle, comorbidities, general health and other factors also affect the outcome and length of recovery.

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Regenerative Stem Cells Knee Pain Treatment London, UK ...

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The Case Against Embryonic Stem Cell Research: An …

December 8th, 2021 1:54 am

Scientists largely agree that stem cells may hold a key to the treatment, and even cure, of many serious medical conditions. But while the use of adult stem cells is widely accepted, many religious groups and others oppose stem cell research involving the use and destruction of human embryos. At the same time, many scientists say that embryonic stem cell research is necessary to unlock the promise of stem cell therapies since embryonic stem cells can develop into any cell type in the human body.

In late 2007, researchers in the United States and Japan succeeded in reprogramming adult skin cells to act like embryonic stem cells. The new development offers the possibility that the controversy over the use of embryos could end. But many scientists and supporters of embryonic stem cell research caution that this advance has not eliminated the need for embryos, at least for the time being.

Recently, the Pew Forum sat down with Yuval Levin, author of Tyranny of Reason, to discuss the ethical and moral grounds for opposing embryonic stem cell research. Previously, Levin was the executive director of the Presidents Council on Bioethics. Currently, he is the Hertog Fellow at the Ethics and Public Policy Center in Washington, D.C., where he also directs the centers Bioethics and American Democracy program.

A counterargument explaining the case for embryonic stem cell research is made by Jonathan Moreno, a professor at the University of Pennsylvania and a senior fellow at the Center for American Progress in Washington, D.C.

Featuring:Yuval Levin, Hertog Fellow and Director of the Bioethics and American Democracy Program, Ethics and Public Policy Center

Interviewer:David Masci, Senior Research Fellow, Pew Forum on Religion & Public Life

Recently, researchers in the United States and Japan successfully turned human skin cells into cells that behave like embryonic stem cells. There has been some discussion that this advance makes the moral and ethical debate over embryonic stem cells moot. Do you think thats an accurate assessment?

I think its going to take a while for the ethical debate to catch up with the science. The scientific community has reacted very positively to this advancement, which was made in November 2007. There have been many additional scientific studies published on the topic since then, and it appears increasingly likely that the cells produced using skin cells are the equivalent of embryonic stem cells. So I think that, in time, this probably will be the final chapter of this particular debate about embryonic stem cells, but I dont think were at the end of it quite yet.

Do you agree with Professor James Thomson, who led the American research team that made this breakthrough, when he maintains that this advance does not, for the time being, abrogate the need for embryonic stem cell research?

Part of his argument for continuing to use embryonic stem cells was backward-looking to make the point that researchers wouldnt have been able to develop this technique if they hadnt been doing embryonic stem cell research. I think thats true, although in a certain way it actually vindicates the logic of President Bushs stem cell policy, which is to allow some work to be done without creating an incentive for the destruction of further embryos to advance the basic science in these kinds of directions.

Thomson also argued that there will still be a need to use embryos in the future. I think thats also a fair argument in the sense that there are always interesting things to learn from different kinds of experiments, but it doesnt address the ethical issues surrounding the debate. If there were no ethical concerns, then certainly the new development wouldnt mean embryonic research would become totally useless. But given that there are concerns, the case for destroying embryos does become a lot weaker. For some people, myself included, the ethical concerns are matters of principle and dont change with new developments.

But for a lot of people, the stem cell debate has always been a matter of balance. People are aware that there are ethical concerns and that there is enormous scientific promise. Now the debate is: Given the ethical questions at stake, is the scientific promise sufficient to make us put the ethical concerns aside and support the research? I think that balance has changed because of this advance, and having an alternative to embryonic stem cell research that achieves the same result will obviously affect the way people think about the ethics of this issue.

That doesnt mean the scientists no longer have any use for embryonic stem cells or even that they wont have any use for them. But I do think it means that people are going to change the way they reason about the balance between science and ethics because of this advance.

I know that you believe that human embryos have intrinsic worth. Do you believe that they have the same intrinsic worth as a five-year-old child or a 50-year-old man?

The question of intrinsic worth is complicated. I dont think it is right to try to determine an embryos intrinsic worth by debating when human life begins. The question of when life begins is a biological question, and the answer actually is fairly straightforward: The life of an organism begins at conception. The ethical question, however, is not about when a life begins but whether every life is equal, and thats a very different question.

I think that the embryonic stem cell debate is ultimately about the question of human equality. The United States has had one answer to that question written in its birth certificate the Declaration of Independence which states that all men are created equal. I think that examining this principle of human equality provides the right answer to this debate, but it is not a simple answer. Human equality doesnt mean that every person is the same or that every person can even be valued in the same way on every scale. What it means is that our common humanity is something that we all share. And what that means, in turn, is that we cant treat a human being in certain ways that we might non-human beings.

The protection of human life comes first. And to the extent that the debate is about whether it is acceptable to destroy a living human being for the purpose of science even for the purpose of helping other human beings I think that in that sense, the embryo is our equal. That doesnt mean that I would think of an embryo in the same way that I would think of a three-year-old child, but I would reject a technique that uses either of them for scientific experimentation.

So in other words, even though you would grieve the death of a 50-year-old man more than a five-day-old embryo, on at least the most basic level you believe that they both have the same right to life.

Yes, thats right. And right to life derives from human equality. The right to life is, in a way, drawn out of the political vocabulary of the Declaration of Independence. And so, to my mind, the argument at the heart of the embryonic stem cell debate is the argument about human equality.

Recently in The New Republic magazine, Harvard psychologist Steven Pinker wrote that conservative bioethicists like yourself consistently predict the worst when looking at developments in biotechnology. He went on to say that had there been a presidents council on cyber-ethics in the 1960s, no doubt it would have decried the threat of the Internet since it would inexorably lead to 1984 or computers taking over like HAL in 2001. How do you respond to this suggestion that there always seems to be this sort of chorus of doomsayers every time something new comes along?

To my mind, biotechnology is fundamentally different from past developments in technology because its directed to the human person. From the beginning of the scientific revolution, science and technology have tried to allow us to manipulate and shape the world around us for the benefit of man. Now that were beginning to manipulate and shape man, the question is: For the benefit of what? In some cases thats easy to see. Obviously curing disease is more of an old-fashioned scientific pursuit. But there are newer scientific developments, such as certain types of human enhancement technologies that raise very complicated questions of how we should judge the ends and the means of technological advancements. That being said, Pinker has a point, in a larger sense that judging the risks of new technologies is very difficult. In general, I think we ought to give the benefit of the doubt to our ability to use new technologies. I dont think that we should assume that the worst will happen. But there are specific instances, which are few but very important, when we do need to be cautious.

Lets shift gears to a question about religion and faith. Obviously there are people of faith on both sides of this debate. In fact, there are conservatives traditional social conservatives, such as Republican Sen. Orrin Hatch of Utah who support embryonic stem cell research. But could you explain how the Judeo-Christian and Western moral ethic informs your views on this issue and why you think that God is ultimately on your side?

Well, I dont know that I think that. My approach to this is not religious. Im not a particularly religious person and I come at this from more of a liberal democratic concern for human equality and the foundations of our society. That being said, those foundations are not utterly secular, and my understanding of them is not utterly secular. I think that to believe in human equality you do have to have some sense of a transcendent standard by which to make that judgment. In other words, when we talk about equality, what do we mean? Equal in relation to what?

Some people have certainly tried to make a purely secular liberal argument for human equality. While I think its very hard to ground a genuine, deep belief in human equality in a worldview that sees nothing above the material, I dont think that that belief depends on specific theological commitments. To my mind, its an American belief more than it is a religious belief.

Certainly I think that President Bushs commitment to human equality has a lot to do with a particular Christian sense of human worth and human value. But I dont think that its necessary to ground yourself in a particular theological or sectarian preference. I think that this is really about whether we believe in a liberal society, which comes from a belief in human equality. The American left, which for the most part is on the other side of this debate from where I am, has always been the champion of human equality, and I think that its a question that they have to really think about.

The Pew Forum and the Pew Research Center for the People & the Press have done polling on this issue over the last six or seven years and have found that Americans generally favor embryonic stem cell research. Why do you think this has happened, and what do you think this trend indicates?

Thats an interesting question. We actually did a poll here at the Ethics and Public Policy Center in February on a similar question, and the lesson I drew from that, and from some other polling thats been done, is that on the stem cell debate, people are just very confused about the facts, and the trend lines have generally followed the sense that cures are coming. In the end, the issue has been misrepresented as a choice between cures and Christianity, and people increasingly think that curing people like Christopher Reeve is just as much of a human good as protecting an embryo that they cant even imagine.

But when you dig down into peoples views about stem cell research, you find a great deal of confusion, and when you put the questions in ethical terms, you find small majorities opposing it. When you put the question in medical terms, you find, I think, somewhat larger majorities supporting it. In our poll, we asked the same people a series of questions that basically put the same issue in several different ways, and their responses are total opposites of one another. The fact that the same people come out on the opposite sides of the same issue when its put in different ways suggests to me that the issue is very hard to understand which it is.

Frequently one hears that, ultimately, you cant stop science or progress and that ethical, moral and religious objections inevitably will fall by the wayside when there are clear material gains to be made. Do you think thats the most likely scenario in this case, assuming the scientific community continues to see a need for embryonic stem cell research?

Well, thats the big assumption, right? To my mind, the aim of people such as myself has always been to find ways of doing the science without violating the ethics rather than to force a choice between the science and the ethics. If we force that choice, I think its more likely that the country would choose science over ethics, and thats exactly why we have to avoid the choice. I dont think we should be overconfident in our ability to persuade people to pass up a material benefit for an ethical principle, although I hope that can be done in the stem cell research debate. It certainly has been done in some instances when the principle was more evident and more obvious such as imposing limits on human subject research.

Again, the aim from my point of view and from a lot of people on my side of this argument has been to find ways to advance the science without violating the ethics. Thats the logic of President Bushs stem cell policy; thats why people have been pushing for alternatives; thats why theyre encouraging the development of these latest alternatives to avoid the choice, not to force the choice. I think thats the best thing for the country, from everybodys point of view. You dont want a situation where youve got sort of red-state medicine and blue-state medicine and people believe that the treatment their hospital is giving them is obtained in unethical ways. That would begin to break up the practice of medicine and to affect our attitudes about science which on the whole has done a tremendous amount of good for society. So I think what everybody should aim for is finding a way to end this potentially very damaging debate rather than force a choice.

This transcript has been edited for clarity, spelling and grammar.

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