StemCell Therapy

"I'm with George Skelton(Los
Angeles Times columnist). Whatever you think about ballot box
budgeting, you could take every penny raised by this and bury it in
the ground - it would still: Reduce smoking (mostly by preventing
some kids, the most price-sensitive group of smokers from starting) .
Save lives. Hurt the lying tobacco companies. All very good things."

CIRM has not taken a position on the measure.

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

by: Steve G. Jones, Ed.S

Obesity is defined as a body mass index (BMI) of 30.0 or greater. BMI is a ratio determined by weight and height. With a large percentage of Americans classified as being obese, research is showing the effects extra weight and obesity have on a person's overall health. Recent studies show that obese people have an increased risk of developing common kidney cancer, kidney stones, and an increased risk of having a stroke.

A study involving 1,640 participants studied the effects of weight on kidney cancer. The average age of patients was 62 and all participants had kidney tumors. The study showed that patients with a BMI of 30 or higher were 48% more likely to develop clear-cell renal cell cancer (RCC). With every 1 point increase in BMI, obese patients increased their odds of getting kidney cancer by 4%.

Out of all the participants, 67% of the obese patients had kidney cancer compared to 57% of non-obese patients. Researchers do not know why there is a link between obesity and kidney cancer. Researchers are looking into a secondary link involving diabetes, hypertension, hormonal changes, and decreased immune function. Read more…

Cardiofy Heart Care Supplement

Source:
http://feeds.feedburner.com/integratedmedicine

The $3 billion California stem cell
agency, which hopes to generate income for the state through the sale
of stem cell therapies, is moving to make its profit-sharing rules
more friendly to business.

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

California biotech companies chalked up
a zero in the latest funding round by the state's $3 billion stem
cell agency, although 14 tried to run a gauntlet that industry has
complained about for years.

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

Two directors of the $3 billion
California stem cell agency have popped up in the battle over the
anti-tobacco initiative on tomorrow's ballot in the Golden State.

"The...problem with Proposition 29
is its pigeonholing of the money for cancer research rather than for
immediate needs here in California that are absolutely dire. It’s
all well and good to say that cancer research benefits everyone, but
the real question is whether it should be the absolute top priority
for a state that can’t afford to keep its children fed or offer
them medical care in the here and now. 

"Lansing and Vuori say the fact
that Prop. 29 'fails to provide funding for schools, roads or
affordable housing' is irrelevant, because it was 'was never intended
to solve these problems.'

"In the context of the state’s
needs, this is a rather callous approach to take. Let’s spell out
why, so Lansing and Vuori won’t be so inclined to dismiss these
necessities of life so casually."

"That’s just the beginning of
what might be cut because the state needs money—and won’t be able
to lay its hands on the hundreds of millions of dollars that Lansing,
Vuori, and their research colleagues are angling for. They don’t
want voters to be reminded that there are competing demands for the
tobacco money, and they do so by failing to mention that they exist,
and also by presenting the spending on cancer research as the voters’
only choice. 

"It’s the only choice because
the promoters of Proposition 29 designed it that way. Advocates of
programs like this love to pass them in via voter initiatives because
they leave no room to measure them against alternative needs."

"Organizers argued that the tax would have
less chance of passing if voters thought it would go into the state
coffers, and said that their only goal here was cutting down on
smoking."

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

The Proposition 71 campaign of 2004,
which has filled the coffers of more than 500 researchers and
institutions with $1.4 billion, was the subject today of a discussion
about miracles.

"Joan Samuelson, a leading
Parkinson's patient advocate, is shown in another ad asserting,
'There are more Americans than I think we can count who are sick
now, or are going to be sick in the future, whose lives will be saved
by Prop. 71.' Shortly after the measure passed, Samuelson was
appointed to the stem cell program's board. 

"Do these ads amount to promising
'miracles'? Given that the essence of scientific research is that no
one can predict the outcome, to assert as fact that 'lives will
be saved by Prop. 71' is plainly to promise something downright
extraordinary, if not outright miraculous. 

"Yes, this is the language of
advertising, not research, but for Trounson and Thomas to pretend
that the ad campaign somehow promised merely 'good science' and not
specific outcomes, as their letter suggested, is (at least)
miraculously disingenuous."

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

The top two leaders of the California
stem cell agency today took strong issue with a column in the Los
Angeles Times that spoke less than favorably about the history and
efforts of the state research enterprise.

"Proposition 71(the stem cell
initiative), you may recall, was sold to a gullible public via
candy-coated images of Christopher Reeve walking again
and Michael J. Fox cured of Parkinson's. The
implication was that these miracles would happen if voters approved a
$3-billion bond issue for stem cell research."

"In his article opposing
Proposition 29, Michael Hiltzik makes a number of misleading
statements about Proposition 71, the voter-approved measure funding
stem-cell research. 

"No ads for Proposition 71
promised miraculous cures. They promised good science, and that is
what is being funded, with more than 62 promising therapies for 40
different diseases on their way to clinical trials. 

"The stem-cell agency has
conflict-of-interest rules as strict as any government agency. We
undergo state-mandated audits to ensure we follow all rules and
regulations, and the most recent one, completed just this month,
praised the agency for its performance. 

"As for being 'an unwieldy
bureaucrac just 6% of the money we get goes to pay for staff; 94%
goes to fund research here in California, creating new jobs,
generating income for the state and, most important, helping find
treatments for deadly diseases."  

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

"Commercialization has emerged as
dominant theme in both the advocacy of science and in the grant
writing process.  But is this push good for science? What damage
might the market’s invisible hand do to the scientific process?"

"There are many recent examples of
how commercialization plays out in top-down policy approaches to
science.  The UK government recently justified a £220 million
investment in stem cell research on the pledge that it will help
stimulate an economic recovery. A 2009 policy document from
Texas made the optimistic prediction that stem cell research could
produce 230,000 regional jobs and $88 billion in state economic
activity.  And President Obama’s 2011 State of the
Union address went so far as to challenge American researchers
to view this moment in time as 'our generation’s Sputnik
moment'—the opportunity to use science and innovation to drive the
economy, create new jobs, and compete with emerging economies, such
as China and India. 

"The impact of this
commercialization pressure is still unfolding, but there is a growing
body of research that highlights the potential challenges, including
the possibility that this pressure could reduce collaborative
behavior, thus undermining scientific progress, and contribute to the
premature application of technologies, as may already be
happening in the spheres of stem cells and genetic
research. For example, might the controversial new Texas stem cell
research regulations, which allow the use of experimental adult
stem cell therapies without federal approval, be, at least in part, a
result of the government’s belief in the economic potential of
the field? 

"Such pressure may also magnify
the growing tendency of research institutions and the media to hype
the potential near future benefits of research—another phenomenon
that might already be occurring in a number of domains and
could have the effect of creating a public expectation that is
impossible to satisfy. 

"Furthermore, how will this trend
conflict with the emerging emphasis on an open approach to
science? A range of national and international policy entities, such
as the Organisation for Economic Co-operation and Development,
suggest 'full and open access to scientific data should be adopted as
the international norm.' Can policy makers have it both ways? 
Can we ask researchers to strive to partner with industry and
commercialize their work and share their data and results
freely and as quickly as practical?"

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

"I think that scientists have an obligation to educate the
public. I welcome visits from both stem cell proponents and
opponents, so I have a chance to clarify any misconceptions about
what it is that we really do. We have to figure out how to deal with
our opponents as well as our friends. I have a policy of welcoming
opponents so I can teach them. It works. Education wins minds."

"Governor Rick Perry left my lab
understanding far more about induced pluripotent stem cells than he
did when he arrived. If we don't engage those who don't share our
views, who will tell them the truth? How will they know that we are
ethical and working to improving human health? 

"The visit was arranged by Michael
Thorsnes, a well-known Democratic fundraiser. He is a very
impressive person who knows politicians of every stripe, and he
arranged the meeting with Perry so that I could explain our project
to make iPSCs from people with Parkinson's disease, and our work
using iPSC derivatives in multiple sclerosis. Perry is promoting
'adult' stem cell therapy in Texas, and I wanted to be sure that he
understood the difference between 'adult' stem cells and pluripotent
stem cells. He does. Educating those in positions of power is one
of our responsibilities, and I take it very seriously."

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

"I'm with George Skelton(Los
Angeles Times columnist). Whatever you think about ballot box
budgeting, you could take every penny raised by this and bury it in
the ground - it would still: Reduce smoking (mostly by preventing
some kids, the most price-sensitive group of smokers from starting) .
Save lives. Hurt the lying tobacco companies. All very good things."

CIRM has not taken a position on the measure.

Source:
http://californiastemcellreport.blogspot.com/feeds/posts/default?alt=rss

In the middle of all the shops, eateries and art galleries on South Main in Memphis, you'll see a red, blue and white flag. That would be the Russian flag, and inside 509 S. Main you can get a taste of the world's largest country -- the Russian Federation.

The Russian Cultural Center opened early this year with the mission of telling Memphis and the Mid-South about a country of almost 150 million that few Americans know much about.

Photo by Dale Anderson // Buy this photo

Beck Niyazov, a native of the former Soviet Union, and Anna Terry are members of New World Connection, the organization that founded the Russian Cultural Center in Memphis. They see the center ultimately as a means to develop business opportunities between Russia and the United States.

"There's so much misinformation about Russia," said Anna Terry, president of New World Connection, the group that created the center. "Americans really don't know much about Russia. They think of the Soviet Union and the Cold War. That was two decades ago. It's all very different now."

The old Soviet Union, that longtime adversary of the U.S., was dissolved in May 1991, and during the past 20 years, a new modern country has emerged, one that Memphians need to get to know better, Terry said.

It was "film night" at the center, and a classic Russian movie was being screened for an audience of about 25.

"People the world over love Memphis' food, culture and music," she said. "So we want to bring some of Russia's food, music and culture to Memphis."

Film night was just one of several events hosted by and planned for the center. Since it opened, there have been history lectures, art showings and musical performances.

Last month, Dr. Valery Kukekov, a stem cell research scientist at St. Jude Children's Research Hospital, was the guest lecturer, presenting an exhibit of his artwork as part of the center's program, "Great Russian Memphians."

See original here:
Russian cultural center seeks to show Memphis new face of old adversary

Functioning liver from stem cells

(AFP) / 9 June 2012

Japanese researchers have created a functioning human liver from stemcells, a report said, raising hopes for the manufacture of artificial organs for those in need of transplants.

A team of scientists transplanted induced pluripotent stem (iPS) cells into the body of a mouse, where it grew into a small, but working, human liver, the Yomiuri Shimbun said.

Stemcells are frequently harvested from embryos, which are then discarded, a practice some people find morally objectionable. But iPS cells which have the potential to develop into any body tissue can be taken from adults.

A team led by professor Hideki Taniguchi at Yokohama City University developed human iPS cells into precursor cells, which they then transplanted into a mouses head to take advantage of increased blood flow.

The cells grew into a human liver 5 millimetres in size that was capable of generating human proteins and breaking down drugs, the Yomiuri reported. The breakthrough opens the door to the artificial creation of human organ. Taniguchis research could be an important bridge between basic research and clinical application but faces various challenges before it can be put into medical practice, the Yomiuri said.

Link:
Functioning liver from stem cells

All in the eyes...the medical breakthrough is a world first. Source: Supplied

A MEDICALl breakthrough by Australian scientists has shown how sheets of stem cells grown on contact lenses can repair damaged eyes.

The treatment transfers minuscule strips of adult stem cells from specifically designed contact lenses onto the eye, to help rebuild the surface of the cornea.

The world-first research could pave the way for an effective treatment for painful caustic or thermal burns, or severe inflammation of the surface of the eye.

Centre for Eye Research Australia researcher Karl David Brown said it was the first time they had proved cells had transferred from the contact lens to the eye to rebuild the surface.

During the trial, limbal stem cells, which function naturally to repair the eye, were taken from the edge of the cornea. Sheets containing hundreds of thousands of cells were grown on contact lenses.

They were inserted in the eye and left for four days. During this time the cells transferred from the lens to the wounded eye.

There are already experimental treatments using human amnion, a membrane that surrounds an embryo, but sourcing the donor tissue after a baby is born and ensuring it is of sufficient quality is difficult.

Brown said the benefit of this new technique was that the cells could be harvested from the patient's own eyes or, if they are too damaged, from donor tissue. Small human trials of the technique are about to start.

"I'm cautiously optimistic that the human trials will yield positive results," Brown said.

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Stem cells used to repair eyes

A medical breakthrough by Australian scientists has shown how sheets of stem cells grown on contact lenses can repair damaged eyes.

The treatment transfers minuscule strips of adult stem cells from specifically designed contact lenses onto the eye, to help rebuild the surface of the cornea.

The world-first research could pave the way for an effective treatment for painful caustic or thermal burns, or severe inflammation of the surface of the eye.

Centre for Eye Research Australia researcher Karl David Brown said it was the first time they had proved cells had transferred from the contact lens to the eye to rebuild the surface.

During the trial, limbal stem cells, which function naturally to repair the eye, were taken from the edge of the cornea. Sheets containing hundreds of thousands of cells were grown on contact lenses.

They were inserted in the eye and left for four days. During this time the cells transferred from the lens to the wounded eye.

There are already experimental treatments using human amnion, a membrane that surrounds an embryo, but sourcing the donor tissue after a baby is born and ensuring it is of sufficient quality is difficult.

Brown said the benefit of this new technique was that the cells could be harvested from the patient's own eyes or, if they are too damaged, from donor tissue. Small human trials of the technique are about to start.

"I'm cautiously optimistic that the human trials will yield positive results," Brown said.

Click for more from the Herald Sun.

Read more here:
Stem cells used to repair damaged eyes in world-first trial

CLEARWATER, FL--(Marketwire -06/08/12)- Biostem U.S., Corporation, (HAIR) (HAIR) (Biostem, the Company), a fully reporting public company in the stem cell regenerative medicine sciences sector, today reported that it has engaged Acropolis Inc. http://www.acropolisinc.com, a full-service advertising agency located in Orlando, Florida, to lend their expertise in brand building, marketing, and advertising development and placement.

Biostem Chief Executive Officer Dwight Brunoehler stated, "After several months of interviewing prospective agencies, we have come to the conclusion that Acropolis is the one to assist us in executing our plans. Their notable work in multiple media areas is impressive, to say the least. Their client list including The University of Florida, Arby's Restaurants, and the City of Orlando, speaks for itself."

Acropolis Principal, Scott Major, said, "This is a great fit for Acropolis. Our entire team loves the Biostem business approach in the incredible field of regenerative medicine. The hair re-growth field in which we will be marketing the Biostem technology is enormous. We are pleased to be a part of Biostem's expansion."

About Biostem U.S. CorporationBiostem U.S., Corporation is a fully reporting Nevada corporation with offices in Clearwater, Florida. Biostem is a technology licensing company with proprietary technology centered on providing hair re-growth using human stem cells. The company also intends to train and license selected physicians to provide Regenerative Cellular Therapy treatments to assist the body's natural approach to healing tendons, ligaments, joints and muscle injuries by using the patient's own stem cells. Biostem U.S., Corporation is seeking to expand its operations worldwide through licensing of its proprietary technology and acquisition of existing stem cell related facilities. The company's goal is to operate in the international biotech market, focusing on the rapidly growing regenerative medicine field, using ethically sourced adult stem cells to improve the quality and longevity of life for all mankind.

For further information, contact Fox Communications Group at 310-974-6821, or view the Biostem website at http://www.biostemus.com.

The rest is here:
Biostem U.S., Corporation Engages Acropolis Agency to Assist in Implementing Its International Marketing Plan

Editor's Choice Main Category: Cardiovascular / Cardiology Article Date: 08 Jun 2012 - 12:00 PDT

Current ratings for: 'Scientists Say They Found A Stem Cell That Causes Heart Disease'

5 (2 votes)

4 (1 votes)

The research is profound because it contradicts much of the generally accepted theories of what causes arterial hardening, and the concept may also relate to many other diseases could the associated stem cells be pinpointed.

What senior author Song Li, a bioengineering professor at UC Berkeley and a researcher at the Berkeley Stem Cell Center, and his team have uncovered is a dormant stem cell in blood vessel walls, that seems to sit inactive for most of a person's lifetime, before coming to life and causing less functional cells to begin to grow. Li says these new types of cells that start growing in later life, are the root cause of arterial hardening and clogging that are associated with deadly strokes and heart attacks.

Originally, it was thought that the smooth muscle cells in the arteries lining become scarred over time, and this leads to the narrow and brittle arteries that play a major part in causing cardiovascular disease. Not so says Liu: Essentially, what the scientists are saying is that the smooth muscle cells are not to blame. Rather a different kind of stem cell, that Li calls multipotent vascular stem cells, kicks in, and begins growing cells that look much like the smooth muscle cells, but don't function correctly. The cells were not found previously, because there are so few of them, that they were hard to isolate.

Li continues:

It almost sounds like something from Bladerunner, where the replicant humans have been deliberately designed to deteriorate and die at a much faster rate than the natural ones. What purpose would it serve the body under standard evolutionary terms to have cells activating later in life that effectively lead to its demise? With the arteries poorly formed, with wrong cell types, the blood flow becomes slowed and can then stopped completely. This causes strokes or heart attacks, depending on the location of the blockage. Strokes and heart attacks are one of the leading causes of death in the United States.

Creating drugs or other genetic treatments to shut down these stem cells or even deactivate them while a person is still young has the potential in the future to prevent arteriole hardening, reverse the damage already done, and even make this type of cardiovascular disease a thing of the past. Perhaps the futuristic Woody Allen movie "Sleeper" where people smoke tobacco and eat a high fat diet because it's healthier is not so far fetched after all.

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Scientists Say They Found A Stem Cell That Causes Heart Disease

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Stem cell therapy offers new treatment options for pets -- and humans

BACKGROUND: Tooth loss, although often associated with a diet high in sugar, has been a problem for as long as mankind has existed. Before the widespread use of refined sugar in food, tooth loss was often a result of disease and malnutrition, although dietary practices also contributed to the problem. Several studies have documented the negative aspects of not having teeth or dentures including impaired nutritional intake, lower self-confidence and self-esteem and reduced quality of life. The three most common tooth replacement options are dental implants, fixed bridges and removable appliances. (Source: perio.org)

STEM CELLS: Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell. (Source: The National Institutes of Health resource for stem cell research)

CLONING TEETH: Nova Southeastern Universitys dental researchers at the College of Dental Medicine are growing and harvesting human dental stem cells in the lab. The cells normally grow in flat layers of single cells in Petri dishes. To get them to form a 3-D tissue structure, researchers seed the cells on tissue engineering scaffolds made from the same polymer material as bio-resorbable surgical sutures. The scaffolds function like those you see around buildings under construction. They provide mechanical support and control the size and shape of a tissue. Once the stem cells are seeded on the scaffolds, researchers add growth factors to signal to the stem cells what type of tissue to grow. The combination of dental stem cells, tissue engineering scaffolds and growth factors allows researchers to engineer new tooth tissues. NSU scientists are working, similar tooth research labs, to create fully functional replacement teeth.

Dental researchers have been successful at regenerating teeth in the laboratory and in animals. They have developed a stem cell therapy for growing new teeth following root canal treatment, and also for replanting teeth that have been knocked out of the mouth. In NSUs technique for regenerating teeth, the pre-clinical trial subjects were able to eat and chew normally. No current studies have examined the ability of animals to eat using completely regenerated teeth because no one has yet regenerated all the teeth in an animal. In NSUs technique, the soft tissue, or pulp, inside teeth was removed and regenerated. The monkey subjects were able to use their teeth normally to eat and chew.

NSU is in the process of patenting a "regeneration kit" that will allow dentists to deliver stem cell therapies to replace dead tissue inside a tooth. In addition, several companies are collecting baby teeth to harvest stem cells through dental offices. The stem cells are being stored for future regenerative therapies, including growing new teeth or growing other replacement organs. (Source: NSU, Sun Sentinel)

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Cloning Teeth: Medicine’s Next Big Thing?

CLEARWATER, FL--(Marketwire -06/08/12)- Biostem U.S., Corporation, (HAIR) (HAIR) (Biostem, the Company), a fully reporting public company in the stem cell regenerative medicine sciences sector, today reported that it has engaged Acropolis Inc. http://www.acropolisinc.com, a full-service advertising agency located in Orlando, Florida, to lend their expertise in brand building, marketing, and advertising development and placement.

Biostem Chief Executive Officer Dwight Brunoehler stated, "After several months of interviewing prospective agencies, we have come to the conclusion that Acropolis is the one to assist us in executing our plans. Their notable work in multiple media areas is impressive, to say the least. Their client list including The University of Florida, Arby's Restaurants, and the City of Orlando, speaks for itself."

Acropolis Principal, Scott Major, said, "This is a great fit for Acropolis. Our entire team loves the Biostem business approach in the incredible field of regenerative medicine. The hair re-growth field in which we will be marketing the Biostem technology is enormous. We are pleased to be a part of Biostem's expansion."

About Biostem U.S. CorporationBiostem U.S., Corporation is a fully reporting Nevada corporation with offices in Clearwater, Florida. Biostem is a technology licensing company with proprietary technology centered on providing hair re-growth using human stem cells. The company also intends to train and license selected physicians to provide Regenerative Cellular Therapy treatments to assist the body's natural approach to healing tendons, ligaments, joints and muscle injuries by using the patient's own stem cells. Biostem U.S., Corporation is seeking to expand its operations worldwide through licensing of its proprietary technology and acquisition of existing stem cell related facilities. The company's goal is to operate in the international biotech market, focusing on the rapidly growing regenerative medicine field, using ethically sourced adult stem cells to improve the quality and longevity of life for all mankind.

For further information, contact Fox Communications Group at 310-974-6821, or view the Biostem website at http://www.biostemus.com.

See the rest here:
Biostem U.S., Corporation Engages Acropolis Agency to Assist in Implementing Its International Marketing Plan