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Pay-for-Eggs Legislation: Strange Bedfellows and Existential Questions

July 14th, 2013 2:57 am
 The California pay-for-eggs bill
today generated a feature article that said the legislation has
“sparked an unusual lineup of partisans on both sides and resonates
far beyond” the Golden State.
The piece by Alex Mathews on Capitol
Weekly
, a news service specializing in California government and
political coverage, said,

“(C)omplicating the issue is
California’s role as a national leader in stem cell research, the
existential question of who or what constitutes a research subject,
and finally, the fact that compensation for fertility purposes is and
has been legal for years in California.”

Mathews was writing about the measure
(AB926) by Assemblywoman Susan Bonilla, D-Concord, that removes a ban
in California on paying women for eggs for scientific research.
Currently women can be paid in California for providing eggs for IVF.
The measure would not alter a ban on compensation for eggs in
research financed by the $3 billion California stem cell agency.
However, later this month, the agency will consider modifying its position somewhat.
The bill has passed the legislature and
is on its way to Gov. Jerry Brown. The industry association
sponsoring the bill expects the governor to sign it later this month
although the governor, as a general rule, does not make public
commitments on legislation.
Mathews' article covered the background
and arguments on the bill and noted that it has received little
mainstream media attention.
Lisa Ikemoto
UC Davis photo
She also quoted Lisa Ikemoto, a law
professor and bioethicist at UC Davis, on the sensitive nature of the
issue. Ikemoto said,

“On the fertility side, it’s
politically hard to touch because it’s all around family formation.
Nobody wants to restrict family formation. On the research side, when
the issue of payment for eggs came up, it was connected with human
embryonic stem cell research, and human embryonic stem cell research
was politicized from the outset.”

Mathews also wrote about the strange
bedfellows opposing the bill. She said,

“Groups that fundamentally oppose
stem cell research such as the California Catholic Conference and
other pro-life groups are natural opponents of the bill, but they are
joined by a number of pro-choice groups who expressed concerns over
the limited research on the effects of egg donation on women’s
health.”

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/pskHpPceyco/pay-for-eggs-legislation-strange.html

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California Stem Cell Merger: Capricor and Niles Therapeutics

July 14th, 2013 2:57 am
Capricor, Inc., a Beverly Hills company
benefiting from $27 million from the California stem cell agency,
this week announced that it is merging with Niles Therapeutic, Inc.,
of San Mateo.
Linda Marban
Capricor photo
The Capricor story and its treatment
for heart disease have been highlighted (see here and here) by the $3
billion state research agency, which is partially funding a clinical
trial for the firm. The firm sprang from work by Eduardo Marban of
Cedars-Sinai in Los Angeles, one of Capricor's founders. He received
$6.9 million for his early and current work. Capricor was awarded
$19.8 million more.
Capricor, a privately held firm, and
the publicly traded Niles announced on Monday that they were merging.
The new company will be known as Capricor Therapeutics, Inc., and will
be based in San Mateo.
The new firm will be publicly traded
with Capricor CEO Linda Marban as the new CEO.
The new board of directors will have
two members from Niles and seven from Capricor, including its
executive chairman, Frank Litvack, who was an unsuccessful candidate for chairman of the stem cell agency board in 2011.
The merger press release said that the
new company “should
have better access to capital, more potential for steady pipeline
development and more risk diversification."
On completion of the merger, a joint
press release said,

Nile
will issue to Capricor stockholders shares of Nile common stock such
that Capricor stockholders will own approximately 90% of the combined
company's outstanding shares, and Nile stockholders will own
approximately 10%, calculated in each case on a fully-diluted basis
assuming the issuance of shares underlying options and warrants.
Options of Capricor will be assumed by Nile and become options to
acquire stock of Nile.”

Linda Marban said,

"Capricor's
and Nile's product portfolios complement each other well, as our
therapies will address both the underlying causes and debilitating
effects of heart disease. Capricor's CDCs are allogeneic cardiac
derived stem cells that aim to attenuate and potentially improve
damage to the heart that can result in heart failure, while Nile's
cenderitide is intended to treat patients following hospital
discharge from an acute episode of heart failure."

Niles' stock price stood at $0.04
recently. Its 52 week high was $0.20 and the 52-week low was $0.02.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/qqVK630tSl0/california-stem-cell-merger-capricor.html

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HIV Clinical Trial Hailed by California Stem Cell Agency

July 14th, 2013 2:57 am
The
California stem cell agency today scored what it called an “important
milestone” with the announcement of the start of a clinical trial
involving a therapy to help protect persons infected with HIV from
the effects of the virus.
The
trial is partially funded from a $20 million award from the stem cell
agency, which is known as CIRM, to researchers
at UCLA and Calimmune, a Tucson, Az.,
company. Calimmune's share of the award was $8.2 million.
Alan
Trounson
, president of the $3 billion state agency, said in a
statement,

CIRM
funding of this Phase l/ll trial is an important milestone for us.
One of our goals is to support research that moves the most promising
science out of the lab and into clinical trials in people. To be able
to do that with a disease as devastating as HIV/AIDS highlights the
importance of our funding and the potential impact it could have on
the health of people around the world.”

The
trial was announced by Calimmune this morning. The company said,

The
first patient has begun treatment in a Phase I/II clinical trial
designed to determine whether a pioneering genetic medicine approach
can help to protect individuals infected with HIV from the effects of
the virus. The study, “
Safety
Study of a Dual Anti-HIV Gene Transfer Construct to Treat HIV-1
Infection
,”
utilizes a gene medicine called Cal-1, developed in the lab of Nobel
Laureate Dr. 
David
Baltimore
 and
by Calimmune.”

Baltimore
served on the CIRM board from 2004 until June 6, 2007. He 
resigned
from the board 
about
18 months before the application process began for the grant round
that ultimately funded Calimmune, a company he helped to found. He is currently chairman of the Calimmune board. 
Asked
for comment, Jeff Sheehy, a member of the CIRM governing
board and communications director for AIDS research at UC San
Francisco
, said,

"This
trial will hopefully offer several important insights into the safety
and feasibility of genetically modifying blood forming stem cells in
an HIV patient as a potential therapy.  We are very early in
this research, and with this Phase I trial's goal of establishing
safety and the risks involved, I applaud the courage and altruism
demonstrated by the patients who are willing to participate in this
study."

The Calimmune
press release
 said
the principal investigators on the clinical trial are 
Ron
Mitsayasu
 of
UCLA and 
Jacob
P. Lalezari
 of Quest
Clinical Research
 of
San Francisco. Quest is currently soliciting patients for the
clinical trial as well as UCLA. (Persons interested in participating
in the trial can find email contacts 
at
this website
.
Twelve are needed.)
The
principal investigators on the CIRM award are Irvin Chen of
UCLA and Geoff Symonds of Calimmune.  

Here are links to the CIRM press release on the subject and the agency's blog item.

(An earlier version of this story did not include the fact that Calimmune's share of the CIRM award was $8.2 million or the links to the agency press release and blog.)

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/Zot_z3D2WnI/hiv-clinical-trial-hailed-by-california.html

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Eggs and Cash: Stem Cell Agency Considering Easing Restrictions on Stem Cell Lines Derived Using Payments

July 14th, 2013 2:57 am
The California stem cell agency is
moving to remove an absolute ban on use of stem cell lines derived
from eggs from women who have been paid to provide them.
The action comes as state legislation
is headed for Gov. Jerry Brown's desk that would permit payments for
eggs to be used in research that is not funded by the agency. The measure (AB926) would not alter the separate ban on egg payments
involving research funded by the $3 billion stem cell agency.
Under a proposal that will come before the agency's standards group July 24, CIRM's governing board could
approve the use of stem cell lines derived as a result of payment to
women. Board action would be based on whether stem cell lines would
“advance CIRM's mission” and would follow a staff evaluation
involving scientific and ethical issues.
Over recent years, stem cell
researchers around the country have reported that they are not able
to obtain sufficient eggs without payment. And earlier this year,
paid egg providers were used in research in Oregon that cloned human stem cells, a feat that researchers have struggled with for years.
A CIRM staff report said that the
Oregon research has “generated scientific interest among CIRM
grantees and the desire to utilize derived SCNT lines. CIRM’s
current policy prohibits the use of the (Oregon) SCNT lines because
oocyte donors were financially compensated. CIRM requests the Medical
and Ethical Standards Working Group (SWG) revaluate this prohibition
with regard to CIRM grantees ability to utilize the resulting lines
in light of recent scientific and policy developments.”
Last month, the California Stem Cell
Report
queried the agency concerning earlier, sketchy information onthe CIRM blog about a possible change in its compensation rules. We
asked whether the agency was considering “sidestepping” the ban
on compensation. Kevin McCormack, a CIRM spokesman, said, “No, not
at all.” He said it would be premature to elaborate until a firm
proposal was ready.
The staff proposal to be considered on
July 24 said,

“Proposition 71’s 'prohibition on
compensation' compels the ICOC(the agency's governing board) to adopt
standards 'prohibiting compensation to research donors.' This
requirement has been consistently interpreted to prohibit the use of
CIRM funds to financially compensate oocyte (or other cell or tissue)
donors. In 2006, this interpretation was extended to exclude from
use, in CIRM-funded research, any stem cell line where research
donors were financially compensated, even if the derivation was done
without the use of CIRM funds. Proposition 71, however, does not
compel the ICOC (the agency's governing board) to prohibit the use of
stem cell lines where financial compensation is provided to the
oocyte donors, provided that CIRM funds are not used to compensate
the donors or derive the lines.”

The July 24 meeting will be held in San
Francisco. No remote teleconference locations have been announced.  If approved, the changes would likely be considered July 25 by the full agency board.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/BF3kpSRnKXQ/eggs-and-cash-stem-cell-agency.html

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California Legislation Removing Ban on Payments for Eggs for Research Heads to Governor

July 14th, 2013 2:57 am
Legislation to allow women in
California to be paid for their eggs for scientific research is on
its way to Gov. Jerry Brown following final legislative approval last
week.
Sponsors of the bill, a national
fertility industry organization, expect the governor later this month
to sign the measure, which would go into effect next year.
The measure, AB 926 by Assemblywoman
Susan Bonilla, D-Concord, would repeal a ban on payments to women who
provide eggs for scientific research. However, the measure would not
affect the ban on payments to egg providers in research funded by the
$3 billion California stem cell agency. That ban is covered by a
separate legal provision. Stem cell researchers around the country have complained that they they cannot get eggs without payment.
Women in California can be paid for
providing eggs for reproductive purposes. According to a legislative analysis, payments can run as high as $50,000 for women with special
characteristics but average around $9,000 for each session, which can
generate more than one egg.
The sponsor of the legislation is the
American Society for Reproductive Medicine of Alabama, whose members
represent a wide swath of the $5 billion-a-year fertility business.
The measure would open new business avenues for the industry.
Bonilla argues that the measure allows women to be treated on the same footing as men who provide sperm for
research and would encourage more research into reproductive health issues.
Opponents argue that the safety of the
egg production procedures has not been well-established including
their long-term impact. They also argue that allowing payment would
lead to exploitation of poor and minority women.
The bill received its final
legislative approval on July 1 when the Senate passed it on a 24-9
vote.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/2FyX5YnnQHA/california-legislation-removing-ban-on.html

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Habib Torfi and stem cell therapy at Invitrx Therapeutics – Video

July 13th, 2013 2:42 am


Habib Torfi and stem cell therapy at Invitrx Therapeutics
Stem Cell Therapy.

By: Habib Torfi

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Habib Torfi and stem cell therapy at Invitrx Therapeutics - Video

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Bone Marrow Stem Cells Help Cerebral Palsy – Andrew’s Testimony – Video

July 12th, 2013 11:51 pm


Bone Marrow Stem Cells Help Cerebral Palsy - Andrew #39;s Testimony
Watch Andrew #39;s Testimonial on how adult bone marrow stem cells helped him and his cerebral palsy. Stem cells are helping cerebral palsy patients today includ...

By: David Steenblock

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Bone Marrow Stem Cells Help Cerebral Palsy - Andrew's Testimony - Video

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Stem cell therapy future of medicine? – Video

July 11th, 2013 10:41 pm


Stem cell therapy future of medicine?
Everyone is talking about stem cell therapy. But scammers and swindlers are also taking advantage of the fad, prompting the Health Department to step in. Bue...

By: Rappler

Here is the original post:
Stem cell therapy future of medicine? - Video

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Stop stem cell therapy – Doctor

July 11th, 2013 10:41 pm

Manila, Philippines -- If she would have her way, Dr. Marita V.T. Reyes, Co-Chairperson of the Philippine Health Research Ethics Board (PHREB), yesterday said she would put a stop to the medical procedure of stem cell therapy.

Reyes delivered a paper yesterday on the topic, "Ethical Consideration In Stem Cell-based Therapy and Research-Poor Countries," on the last day of the 35th Annual Scientific Meeting of the Department of Science and Technology-National Academy of Science and Technology (DOST-NAST) at the historic landmark Manila Hotel.

Reyes acknowledged that there is a "standard" stem cell therapy treatment involving "hematopoietic disorders," such as "leukemia and lymphomas," through "bone marrow or cord blood transplant."

She, however, emphasized that this cannot be said yet in the cases of diseases of the heart, eyes, diabetes, stroke, spinal cord injury, Parkinson's, Alzheimer's, Lou Gehrig's (ALS), multiple sclerosis, cancer, and cartilage repair.

Stem cell therapy for these diseases, she stressed, should be stopped.

"If I have the power, I will say, 'stop this in the meantime, until the Food and Drug Administration (FDA) has come up with a quality assurance. Until the FDA is able to say that what you say is there, is there, we have no way of protecting our people," said Reyes, when asked about the ethics board's possible advice.

"So, as far as I am concerned, I would like the stem cell therapy, meaning for people who are saying they are using stem cell therapy, to stop, until we have set up very clear quality assurance (system)," the PHREB official said.

Stem cell therapy discussions resulted from the reported death of three Filipino politicians, and the complaint of a government official, after allegedly subjecting themselves from the controversial medical procedure.

Dr. Francisco Chung, Jr., of the Makati Medical Center (MMC), on the other hand, conceded that there are many stem cell procedures that are "experimental in nature."

"What we have approved clinically is bone marrow transplantation," he said, citing the approval of the United States Food and Drug Administration (USFDA).

Read this article:
Stop stem cell therapy – Doctor

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Anti Aging Options for Healthy Adult Stem Cells and Body Renewal – Video

July 11th, 2013 8:44 pm


Anti Aging Options for Healthy Adult Stem Cells and Body Renewal

By: miraclecell

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Anti Aging Options for Healthy Adult Stem Cells and Body Renewal - Video

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Stem Cell Therapy for Knee Pain: Safer than Surgery

July 10th, 2013 3:49 pm

TAMPA, Fla., July 9, 2013 /PRNewswire/ -- Stem Cell Therapy for knee joint pain has been involved in multiple clinical trials worldwide. In the United States trials for knee arthritis and back pain with degenerative disc disease have undergone safety trials and phase studies for effectiveness. The safety profile for stem cell therapy in joints has been proven. Adverse effects are not seen as related to the stem cells. These studies were conducted with allogenic (other people's) stem cells. Naturally, if using your own stem cells, the issues which may be raised from someone else's stem cells is not a concern, and are therefore even safer. There are no immune rejection issues or communicable diseases that can be obtained by using your own cells.

Stem Cell Therapy for joints also do not carry surgical risks such as anesthesia, there is no greater risk for other postoperative complications such as blood clots, infections, or need for revision surgery if it is unsuccessful. Dr. Dennis Lox, a Regenerative and Sports Medicine physician in the Tampa Bay, Florida area (www.drlox.com), comments, "Surgery for joint replacement does carry some significant risks, as this is a highly invasive surgery. Knee and other joint replacement surgery consent forms do include the complication of death. More common problems are infection and blood clots. Stem Cell Therapy injections for joints are no more difficult than injecting cortisone into the knee," states Dr. Lox."There is preparation involved to get to that point, however the injection can be a simple, same-day, office-based procedure."

Dr. Lox notes, "Stem Cell Therapy for joint repair has been used for acute and chronic injuries, knee meniscal tears, loss of knee joint cartilage, and to stop the progression of degenerative arthritis. Even avascular necrosis (AVN) or osteonecrosis has been treated with Stem Cell Therapy. The secondary arthritis from joint collapse in avascular necrosis (AVN) can be significant leading to knee joint replacement. The useof stem cells is becoming a more common alternative to joint replacement."

Dr. Lox further notes, "Some patients may have already had one knee joint replaced with a bad outcome, and wish to avoid a second knee replacement. Others may not be healthy enough. Some medical disorders such as bad hear ailments may preclude having a knee replacement. In these cases, having a regenerative medicine procedure is an attractive, conservative option. Patients who are not medically suited for joint or knee replacement are generally good candidates for Stem Cell Therapy. The pursuit of conservative options in patients who wish to avoid surgery for joint disorders, may find Stem Cell Therapy as an attractive alternative."

About Dr. Dennis Lox Dr. Lox practices in the Tampa Bay Florida area. Dr. Lox is a Sports and Regenerative Medicine Physician, who specializes in the use of regenerative and restorative medicine to assist in treating athletic and arthritis conditions. Dr. Lox may be reached at (727) 462-5582 or visit Drlox.com.

http://www.drlox.com

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Stem Cell Therapy for Knee Pain: Safer than Surgery

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Treatment for Spinal Cord Injury with Stem Cells Therapy – Video

July 10th, 2013 10:45 am


Treatment for Spinal Cord Injury with Stem Cells Therapy
Treatment for Spinal Cord Injury with Stem Cells Therapy, successfully results , after receiving the Stem Cells Treatment patient is regaining leg feeling and capable to perform initial movements...

By: enjades

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Treatment for Spinal Cord Injury with Stem Cells Therapy - Video

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Stem Cells For Spinal Cord Injury successfully results – Video

July 10th, 2013 10:45 am


Stem Cells For Spinal Cord Injury successfully results
Stem Cells For Spinal Cord Injury successfully results, Performed by NeuroSurgeon Dr. Luis Jorge Quintero, patient was treated with Stem Cells Therapy and ge...

By: enjades

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Stem Cells For Spinal Cord Injury successfully results - Video

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Jeunesse® Global Revolutionary Anti Aging Skin Care with Stem Cells – Video

July 10th, 2013 10:45 am


Jeunesse® Global Revolutionary Anti Aging Skin Care with Stem Cells
Info / Join Online : http://www.Network888.JeunesseGlobal.com At Jeunesse®, we #39;ve turned science fiction into science fact. We #39;re redefining youth and shifti...

By: JeunesseNetwork

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Jeunesse® Global Revolutionary Anti Aging Skin Care with Stem Cells - Video

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Stem Cell Therapy Treatment for Duchenne Muscular Dystrophy by Dr Alok Sharma, Mumbai, India. Part 2 – Video

July 9th, 2013 12:49 pm


Stem Cell Therapy Treatment for Duchenne Muscular Dystrophy by Dr Alok Sharma, Mumbai, India. Part 2
Improvement seen in just 3 months after Stem Cell Therapy Treatment for Duchenne Muscular Dystrophy by Dr Alok Sharma, Mumbai, India. After Stem Cell Therapy...

By: Neurogen Brain and Spine Institute

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Stem Cell Therapy Treatment for Duchenne Muscular Dystrophy by Dr Alok Sharma, Mumbai, India. Part 2 - Video

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Stem cell therapy future of medicine?

July 9th, 2013 12:49 pm

by Rappler.com Posted on 07/09/2013 9:42 PM |Updated 07/09/2013 10:20 PM

MANILA, Philippines - Everyone is talking about stem cell therapy. But scammers and swindlers are also taking advantage of the fad, prompting the Health Department to step in. Buena Bernal reports.

Its the new medical buzzword in the Philippines. Stem cell therapy is a procedure which uses repair cells found in the body to replace old cells. Dr Florencio Lucero started doing the procedure 6 years ago.

DR FLORENCIO LUCERO, STEM CELL TRANSPLANT SURGEON: Stem cells can help degenerative diseases. Some people who have serious illnesses, and they cannot find any solution to their condition, they seek this kind of treatment, because it can improve their condition. But not a cure. It cannot cure.

Stroke survivor Pilar Vasquez says she felt energized after undergoing the treatment.

PILAR VASQUEZ, STEM CELL TRANSPLANT PATIENT: Stem cell is very good. I did not feel pain or what. Everything is very good. Before, I dont talk. Now, I always talk. Thats a very good difference, because now they say, Ay si Mommy, ang galing galing niyan, parating nagsasalita!

But stem cell therapy became controversial after 3 government officials allegedly died from the treatment, while another official filed charges against his German doctor for his botched treatment last year. Food and Drug Administration director Dr. Kenneth Hartigan Go says right now, stem cell therapy is allowed but under investigation.

DR KENNETH HARTIGAN-GO, DIRECTOR, FOOD AND DRUG ADMINISTRATION: We are keeping an objective mind and saying, okay, if this is investigational, go ahead. And then we have to see outcome, say, within a period of a time whether the product actually works or not.

The Department of Health cautions the public from engaging in prohibited forms of the treatment -- those that are performed outside accredited facilities and those that source stem cells from human embryos. Health Secretary Enrique Ona says he does not want to stifle the innovation but there must be regulation.

View original post here:
Stem cell therapy future of medicine?

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Anti aging + Multiple Disorders Treatment using stem cells – Video

July 9th, 2013 6:45 am


Anti aging + Multiple Disorders Treatment using stem cells
THE ADVANTAGES Of A Fat Stem Cell Anti-Aging Treatment Stem Cells from your own body are used No chemicals or drugs are needed Better breathing and sleeping pattern. Energy levels restored...

By: StemRx BioScience

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Anti aging + Multiple Disorders Treatment using stem cells - Video

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Cerebral Palsy treatment using stem cells – Video

July 9th, 2013 6:45 am


Cerebral Palsy treatment using stem cells
Cerebral Palsy can be treated with stem cell therapy. know more at http://www.stemrx.in.

By: StemRx BioScience

Originally posted here:
Cerebral Palsy treatment using stem cells - Video

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Testimonial: Heart Attack, Kidney Failure, Hyperuricemia (Mr. Say Bee) – Video

July 9th, 2013 6:44 am


Testimonial: Heart Attack, Kidney Failure, Hyperuricemia (Mr. Say Bee)
Follow me on YouTube and Facebook for more updates and information! Contact Evelyn @ +65 8699 5092 Facebook: Purtier - Live Stem Cell Therapy.

By: PurtierSG

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Testimonial: Heart Attack, Kidney Failure, Hyperuricemia (Mr. Say Bee) - Video

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Purtier NZ Live Stem Cell Therapy presented by Dr Chen – Video

July 9th, 2013 6:43 am


Purtier NZ Live Stem Cell Therapy presented by Dr Chen
For Live demo and discussion: Call John 90036287 / Daphne 91455217.

By: petty joy

Visit link:
Purtier NZ Live Stem Cell Therapy presented by Dr Chen - Video

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