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The Science of Mesenchymal Stem Cells and Regenerative Medicine – Arnold Caplan PhD (Part 6) – Video

June 24th, 2013 12:42 pm


The Science of Mesenchymal Stem Cells and Regenerative Medicine - Arnold Caplan PhD (Part 6)
In part 6, Prof. Caplan discusses Trophic properties of mesenchymal stem cells; MSCs for heart disease; MSCs homing to heart injury site and also to skin inc...

By: http://www.cellmedicine.com

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The Science of Mesenchymal Stem Cells and Regenerative Medicine - Arnold Caplan PhD (Part 6) - Video

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Keynote address – Lord John Krebs – World Stem Cells Regenerative Medicine Congress – Video

June 24th, 2013 12:42 pm


Keynote address - Lord John Krebs - World Stem Cells Regenerative Medicine Congress
Lord John Krebs, chairman of the House of Lords Science and Technology Committee gives his presentation on #39;Mapping a route for the commercialisation of cell...

By: biopharmachannel

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Keynote address - Lord John Krebs - World Stem Cells Regenerative Medicine Congress - Video

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Commercialisation through collaboration – Ed Field – World Stem Cells Regenerative Medicine – Video

June 24th, 2013 12:42 pm


Commercialisation through collaboration - Ed Field - World Stem Cells Regenerative Medicine
Ed Field, Chief Operating Officer at Cytomedix gives his presentation on #39;Commercialisation through collaboration: what does partnering in this industry actu...

By: biopharmachannel

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Commercialisation through collaboration - Ed Field - World Stem Cells Regenerative Medicine - Video

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Health economics – Prof. Richard Lilford – World Stem Cells Regenerative Medicine Congress 2013 – Video

June 24th, 2013 12:42 pm


Health economics - Prof. Richard Lilford - World Stem Cells Regenerative Medicine Congress 2013
Prof. Richard Lilford, Clinical Epidemiology, Public Health Biostatistics at the University of Birmingham gives his presentation on #39;Health economics: how ...

By: biopharmachannel

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Health economics - Prof. Richard Lilford - World Stem Cells Regenerative Medicine Congress 2013 - Video

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World Courier Logistics Ltd. – World Stem Cells Regenerative Medicine Congress 2013 – Video

June 24th, 2013 12:42 pm


World Courier Logistics Ltd. - World Stem Cells Regenerative Medicine Congress 2013
We spoke with some of the sponsors at Europe #39;s largest stem cells and regenerative medicine industry conference. This is a three day congress that stages a s...

By: biopharmachannel

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World Courier Logistics Ltd. - World Stem Cells Regenerative Medicine Congress 2013 - Video

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Alternative financing models – Navid Malik – World Stem Cells Regenerative Medicine Congress – Video

June 24th, 2013 12:42 pm


Alternative financing models - Navid Malik - World Stem Cells Regenerative Medicine Congress
Navid Malik, Head of Life Science Research at Cenkos Securities gives his presentation on #39;Alternative financing models: floating on the stock markets to gai...

By: biopharmachannel

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Alternative financing models - Navid Malik - World Stem Cells Regenerative Medicine Congress - Video

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Chairman’s Opening Remarks – Prof. Chris Mason – World Stem Cells Regenerative Medicine Congress – Video

June 24th, 2013 12:42 pm


Chairman #39;s Opening Remarks - Prof. Chris Mason - World Stem Cells Regenerative Medicine Congress
Prof. Chris Mason from the Regenerative Medicine Bioprocessing Unit, Advanced Centre for Biochemical Engineering at the University College London gives the C...

By: biopharmachannel

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Chairman's Opening Remarks - Prof. Chris Mason - World Stem Cells Regenerative Medicine Congress - Video

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International team submits IND application

June 23rd, 2013 3:02 am

On 18 June 2013, there was an announcement at the Princess Margaret Cancer Centre, Toronto. There was also a post on the California stem cell agency blog entitled: Clinical trial to thwart cancer stem cells may begin soon. An excerpt from the post:

The Prince Margaret Center announced the FDA filing, called an Investigational New Drug application (IND), at an event in Toronto recognizing the private donors. A press release about the announcement was picked up at this biotech news site.

The Principal Investigators present for the announcement were Dr. Tak Mak of the Princess Margaret Cancer Centre and Dr. Dennis Slamon of the University of California, Los Angeles (UCLA). What they have done is summarized in another excerpt from the blog post:

By working first to understand the various proteins that drive cells to divide, particularly in cancer, they were able to pinpoint an enzyme, that if blocked, could be the key to keeping cancer in check. They then discovered that this enzyme, called PLK4, can be derailed by a new drug they developed. In the lab, it has been shown to inhibit the growth of breast, ovarian, colorectal, lung, pancreatic and prostate cancer, as well as melanoma.

Information about the human PLK4 protein is available here.

Some background: In June 2008, it was announced that a partnership had been formed between Canada’s Cancer Stem Cell Consortium (CSCC) and the California Institute for Regenerative Medicine (CIRM) for international collaboration to advance cancer stem cell research. An excerpt from the CSCC's announcement:

It is proposed that one of the first initiatives to be launched by the CSCC will be a collaboration between Canadian and Californian scientists through CIRM's upcoming Disease Team Research Awards Competition, which will support multi-disciplinary teams of scientists in pursuit of therapies for specific diseases.The goal is to fund teams that will develop therapy or diagnostics for a particular disease or serious injury.Successful proposals will likely include a description of a path to an Investigational New Drug filing at the end of the four-to-five year grant.

Note the intent to file an IND by the end of the term of the grant.

The results of the Disease Team Research Awards Competition were announced on October 28, 2009. The award to Drs. Slamon and Mak is Grant number DR1-01477. See: Therapeutic Opportunities to Target Tumor Initiating Cells in Solid Tumors. As was stated in a page about Cancer Stem Cells on the website of the Canadian Institutes for Health Research (CIHR), this award was to one of two multi-disciplinary research teams co-led by Canadian and Californian scientists. The other team is co-led by Dr. John Dick of the University Health Network and Dr. Dennis Carson of the University of California, San Diego. My blog post (October 29, 2009) about the awards is entitled: Disease Team awards announced. The post ends with this Disclosure:

I'm a member of the Board of the CSCC, but also a staff member (emeritus) at the University Health Network. So, I was in conflict of interest, and was absent during all of the discussions, by the CSCC Board, about which Canadian applications should be considered for the Disease Team awards.

Source:
http://cancerstemcellnews.blogspot.com/2013/06/international-team-submits-ind.html

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Pay-For-Eggs Legislation Draws More Media Attention

June 23rd, 2013 3:02 am
California legislation to allow women
to be paid for their eggs for scientific research generated several news articles this week as the measure neared final legislative
approval.
The coverage included both pro and con
but did not amount to major attention from the mainstream media. And,
with one exception, the articles failed to report that the
legislation did not apply to research funded by the $3 billion
California stem cell agency, which bans compensation for egg
providers.
The proposal (AB926) is now on the
state Senate floor with a vote possibly coming as early as next
Thursday. A spokesman for the American Society for Reproductive
Medicine
in Birmingham, Ala., an industry group sponsoring the bill,
said unequivocally that the Gov. Jerry Brown is expected to sign the
measure. (See the Senate floor bill analysis here and a press release on the bill here.)
Assemblywoman Susan Bonilla
Photo Source -- Bonilla's office
The articles about the legislation by
Assemblywoman Susan Bonilla, D-Concord, have appeared in the journal
Nature, the San Francisco Chronicle and the Huffington Post over the
past few days.
Alice Crisci, a California patient
advocate writing on the Huffington Post, yesterday remarked that
women egg providers should be treated the same as men involved in
scientific experiments.

“After all, aren't we past the days
when we treat women like they are less capable than men of making
sound decisions for their own well-being? It's my body and my choice
if I want to donate a dozen of my eggs to science. Who knows -- maybe
it's my egg that will be used to find a cure for cancer.”

Debra Saunders, writing a column in the
Chronicle on Sunday, said,

“That sperm-egg parity argument is so
bogus. When men donate sperm, they risk second thoughts about
unknown, random offspring, but they do not risk serious medical side
effects. Egg donation, on the other hand, can be hazardous to your
health. The New York Times reports, "Egg donors can suffer
serious side effects from the powerful hormones needed to generate
multiple eggs." And: "The most significant risk is ovarian
hyper-stimulation syndrome, which can cause bloating, abdominal pain
and, rarely, blood clots, kidney failure and other life-threatening
ailments."

Charlotte Schubert, writing in Nature
on Tuesday, said,

“In practical terms, the bill would
bump up payments from hundreds to thousands of dollars. In Oregon —
which, like most states, does not have regulations governing egg
donation — women recently received $3,000–7,000 each for eggs
used in a study that created stem-cell
lines from cloned human embryos
.”

Prices for eggs can run substantially higher depending on the characteristics of the supplier.
Bonilla's office said the bill did not
come up for a vote during today's Senate floor session but could come
up next Thursday.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/O3i-n3NxdnA/pay-for-eggs-legislation-draws-more.html

Read More...

International team submits IND application

June 23rd, 2013 2:59 am

On 18 June 2013, there was an announcement at the Princess Margaret Cancer Centre, Toronto. There was also a post on the California stem cell agency blog entitled: Clinical trial to thwart cancer stem cells may begin soon. An excerpt from the post:

The Prince Margaret Center announced the FDA filing, called an Investigational New Drug application (IND), at an event in Toronto recognizing the private donors. A press release about the announcement was picked up at this biotech news site.

The Principal Investigators present for the announcement were Dr. Tak Mak of the Princess Margaret Cancer Centre and Dr. Dennis Slamon of the University of California, Los Angeles (UCLA). What they have done is summarized in another excerpt from the blog post:

By working first to understand the various proteins that drive cells to divide, particularly in cancer, they were able to pinpoint an enzyme, that if blocked, could be the key to keeping cancer in check. They then discovered that this enzyme, called PLK4, can be derailed by a new drug they developed. In the lab, it has been shown to inhibit the growth of breast, ovarian, colorectal, lung, pancreatic and prostate cancer, as well as melanoma.

Information about the human PLK4 protein is available here.

Some background: In June 2008, it was announced that a partnership had been formed between Canada’s Cancer Stem Cell Consortium (CSCC) and the California Institute for Regenerative Medicine (CIRM) for international collaboration to advance cancer stem cell research. An excerpt from the CSCC's announcement:

It is proposed that one of the first initiatives to be launched by the CSCC will be a collaboration between Canadian and Californian scientists through CIRM's upcoming Disease Team Research Awards Competition, which will support multi-disciplinary teams of scientists in pursuit of therapies for specific diseases.The goal is to fund teams that will develop therapy or diagnostics for a particular disease or serious injury.Successful proposals will likely include a description of a path to an Investigational New Drug filing at the end of the four-to-five year grant.

Note the intent to file an IND by the end of the term of the grant.

The results of the Disease Team Research Awards Competition were announced on October 28, 2009. The award to Drs. Slamon and Mak is Grant number DR1-01477. See: Therapeutic Opportunities to Target Tumor Initiating Cells in Solid Tumors. As was stated in a page about Cancer Stem Cells on the website of the Canadian Institutes for Health Research (CIHR), this award was to one of two multi-disciplinary research teams co-led by Canadian and Californian scientists. The other team is co-led by Dr. John Dick of the University Health Network and Dr. Dennis Carson of the University of California, San Diego. My blog post (October 29, 2009) about the awards is entitled: Disease Team awards announced. The post ends with this Disclosure:

I'm a member of the Board of the CSCC, but also a staff member (emeritus) at the University Health Network. So, I was in conflict of interest, and was absent during all of the discussions, by the CSCC Board, about which Canadian applications should be considered for the Disease Team awards.

Source:
http://cancerstemcellnews.blogspot.com/2013/06/international-team-submits-ind.html

Read More...

Pay-For-Eggs Legislation Draws More Media Attention

June 23rd, 2013 2:59 am
California legislation to allow women
to be paid for their eggs for scientific research generated several news articles this week as the measure neared final legislative
approval.
The coverage included both pro and con
but did not amount to major attention from the mainstream media. And,
with one exception, the articles failed to report that the
legislation did not apply to research funded by the $3 billion
California stem cell agency, which bans compensation for egg
providers.
The proposal (AB926) is now on the
state Senate floor with a vote possibly coming as early as next
Thursday. A spokesman for the American Society for Reproductive
Medicine
in Birmingham, Ala., an industry group sponsoring the bill,
said unequivocally that the Gov. Jerry Brown is expected to sign the
measure. (See the Senate floor bill analysis here and a press release on the bill here.)
Assemblywoman Susan Bonilla
Photo Source -- Bonilla's office
The articles about the legislation by
Assemblywoman Susan Bonilla, D-Concord, have appeared in the journal
Nature, the San Francisco Chronicle and the Huffington Post over the
past few days.
Alice Crisci, a California patient
advocate writing on the Huffington Post, yesterday remarked that
women egg providers should be treated the same as men involved in
scientific experiments.

“After all, aren't we past the days
when we treat women like they are less capable than men of making
sound decisions for their own well-being? It's my body and my choice
if I want to donate a dozen of my eggs to science. Who knows -- maybe
it's my egg that will be used to find a cure for cancer.”

Debra Saunders, writing a column in the
Chronicle on Sunday, said,

“That sperm-egg parity argument is so
bogus. When men donate sperm, they risk second thoughts about
unknown, random offspring, but they do not risk serious medical side
effects. Egg donation, on the other hand, can be hazardous to your
health. The New York Times reports, "Egg donors can suffer
serious side effects from the powerful hormones needed to generate
multiple eggs." And: "The most significant risk is ovarian
hyper-stimulation syndrome, which can cause bloating, abdominal pain
and, rarely, blood clots, kidney failure and other life-threatening
ailments."

Charlotte Schubert, writing in Nature
on Tuesday, said,

“In practical terms, the bill would
bump up payments from hundreds to thousands of dollars. In Oregon —
which, like most states, does not have regulations governing egg
donation — women recently received $3,000–7,000 each for eggs
used in a study that created stem-cell
lines from cloned human embryos
.”

Prices for eggs can run substantially higher depending on the characteristics of the supplier.
Bonilla's office said the bill did not
come up for a vote during today's Senate floor session but could come
up next Thursday.

Source:
http://feedproxy.google.com/~r/blogspot/uqpFc/~3/O3i-n3NxdnA/pay-for-eggs-legislation-draws-more.html

Read More...

How stem cells are extracted from cloned human skin cells – Video

June 23rd, 2013 2:44 am


How stem cells are extracted from cloned human skin cells
Earlier this week, researchers published in the journal Cell that they had created embryonic stem cells by cloning human skin cells. An embryo is usually cre...

By: TomoNewsUS

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How stem cells are extracted from cloned human skin cells - Video

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First dog on Oahu gets stem cell therapy – Video

June 20th, 2013 9:45 pm


First dog on Oahu gets stem cell therapy
A 13-year-old dog who was barely able to walk is back on his paws thanks to stem cell therapy. Before the treatment Kumba suffered from arthritis so bad he c...

By: Joem Costes

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First dog on Oahu gets stem cell therapy - Video

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SyStemAge: Hematopoietic Stem Cells – Video

June 20th, 2013 11:48 am


SyStemAge: Hematopoietic Stem Cells
Hematopoietic Stem Cells (HSC - that can differentiate into blood cells or cells of the immune system) in culture grow more efficiently when in contact with ...

By: HorizonHealthEU

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SyStemAge: Hematopoietic Stem Cells - Video

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Do you talk to your stem cells? — ISSCR Fun with Life Technologies – Video

June 20th, 2013 11:48 am


Do you talk to your stem cells? -- ISSCR Fun with Life Technologies
What do you say to your stem cells when no one is around? Hear what scientists at ISSCR are saying to their cells. Visit http://www.lifetechnologies.com/stem...

By: LifeTechnologiesCorp

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Do you talk to your stem cells? -- ISSCR Fun with Life Technologies - Video

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American Health Journal PBS Special Laminine Stem Cell Therapy Full Version – Video

June 20th, 2013 11:47 am


American Health Journal PBS Special Laminine Stem Cell Therapy Full Version
http://www.LaminiNHealth.com/dc/ Doctors are interviewed about Fibroblast Growth Factor, Laminin, Cortisol, Serotonin Do-It-Yourself Stem Cell Therapy - La...

By: David Dolores

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American Health Journal PBS Special Laminine Stem Cell Therapy Full Version - Video

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ASCI Two Worlds of Stem Cell Therapy Animation – Video

June 19th, 2013 2:42 pm


ASCI Two Worlds of Stem Cell Therapy Animation
Asian Stem Cell Institute (ASCI) Two Worlds of Stem Cell Therapy Animation Autologous Stem cell Treatments, mobilized peripheral blood, bone marrow and adipo...

By: stemcellregeneration

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ASCI Two Worlds of Stem Cell Therapy Animation - Video

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ASCI – TWO WORLDS OF STEM CELLS – Video

June 19th, 2013 4:49 am


ASCI - TWO WORLDS OF STEM CELLS
ASCI - Asian Stem Cell Institute - http://www.stem-cell-regeneration.com/

By: VIDUMO Team

Excerpt from:
ASCI - TWO WORLDS OF STEM CELLS - Video

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Wellington Chen, M.D. of Advanced Rejuvenation Introduces Stem Cell Therapy For OsteoArthritis & COPD in Sarasota …

June 18th, 2013 10:41 am

Sarasota, Florida (PRWEB) June 18, 2013

After almost 20 years of performing regenerative treatments in the field of non surgical orthopedics, Wellington Chen, M.D., will begin conducting clinical trials for many degenerative diseases using adipose-derived stem cell therapy in Sarasota, Florida. The independent review board of the International cell medicine society is responsible for overseeing these trials.

Advanced Rejuvenation will treat patients suffering from chronic obstructive pulmonary disease (COPD) and osteoarthritis following the IRB-approved protocols. Advanced Rejuvenation will be using adult autologous stem cells, harvested from the patients own adipose (fat) tissue or bone marrow if fat is not available. Because patients are receiving their own cells, there is no risk of rejection. As of 2007, over 9,000 studies have shown the safety using these cell lines.

Autologous stem cell therapy are your bodies repair men. They are circulated throughout your body and as soon as there is a need for them, chemical messages trigger them to migrate to the area and do their magic. They are both immune modulating and also regenerative which makes them a great therapeutic agent for osteoarthritis and COPD. Numerous studies have shown them to have the capacity to grow new cartilage, muscle, ligaments, glands and even organs. We believe stem cell treatments will become the future of care for most orthopedic problems avoiding the need for surgery. With COPD, when stem cells are run into the blood stream through an IV they will mostly pass through the lungs. We are excited to be apart of these research studies.

Advanced Rejuvenation trained under scientist Kristin Comella, CEO of Stemlogix. She was recently named in the Wall Street Journal as one of the 50 most influential people on stem cell research. Advanced Rejuvenation will implement Stemlogixs patented extraction process, allowing for an exceptionally high yield and viability of stem cells from fat.

During the in-office and same day procedure, a mini liposuction is performed. A half of a cup of fat in harvested from around the abdominal region which produces approximately 8 million stem cells. The stem cells are isolated put back into the patients joints or with COPD via an IV infusion. Local anesthesia is all that is needed and pain medication can be prescribed but is rarely necessary.

Advanced Rejuvenation has treated various orthopedic conditions for 4 years using fat transfer and now offers these treatments to patients ranging from NFL players to retired golfers. If you would like more information, e-mail Advanced Rejuveantion at AskDrGecko(at)Gmail(dot)com or call our office.

About Advanced Rejuvenation

Advanced Rejuvenation is a multi specialty practice in Sarasota, Florida, specializing in regenerative treatments such as Stem Cell Treatments, Prolotherapy, Ozone Therapy, Naturopathic, Acupuncture, Chiropractic Functional Neurology, Osteopathy, Functional Medicine, Active Isolated Stretching (AIS)

Contact: Advanced Rejuvenation Phone: (941) 330-8553 E-mail: AskDrGecko(at)Gmail(dot)com Website: http://www.SarasotaStemCell.com Office address: 2033 Wood Street #210 Sarasota, Florida 34237

Read the rest here:
Wellington Chen, M.D. of Advanced Rejuvenation Introduces Stem Cell Therapy For OsteoArthritis & COPD in Sarasota ...

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How to Use Stem Cells to Repair Hip Joints – Video

June 18th, 2013 12:44 am


How to Use Stem Cells to Repair Hip Joints
Dr. Alex Martin discusses the use of stem cell therapy to repair damaged hip joints. For more info, please call (323) 285-5300 or email info@metromd.net or v...

By: MetroMD

Here is the original post:
How to Use Stem Cells to Repair Hip Joints - Video

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