StemCell Therapy

RSCI Don Margolis Stem Cells 101 #06
The best stem cell treatment center.

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RSCI Don Margolis Stem Cells 101 #06 - Video

Stem cells for treatment of ALS at Mayo Clinic
Researchers in the Center for Regenerative Medicine are studying the use of intraspinal deliver of mesenchymal stem cells (MSCs) to the cerebral spinal fluid...

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Stem cells for treatment of ALS at Mayo Clinic - Video

SA STGEC G G GR: Stem Cells in Aging (2009)
April 2nd, 2009 San Antonio STGEC Geriatrics Gerontological + Palliative Medicine Grand Rounds re: "Stem Cell-Based Therapy: Potential for Age-Related Dise...

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SA STGEC G&G GR: Stem Cells in Aging (2009) - Video

Human Longevity, Inc. Conference Call Audio (March 4, 2014)
Human Longevity Inc. (HLI) Launched to Promote Healthy Aging Using Advances in Genomics and Stem Cell Therapies. HLI is Building World #39;s Largest Genotype/Phe...

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Human Longevity, Inc. Conference Call Audio (March 4, 2014) - Video

21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(After)
After treatment: The patient received four times of stem cell treatment in our center. His overall condition improved a lot after the treatment. The injury l...

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21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(After) - Video

Google stem cell therapy and a whole host of results show up. Stem cell therapy for hair loss, diabetes, cancer and practically everything else. It is touted as the medicine of hope, the panacea for all ills.

But to ensure that this potentially-powerful technology is not misused in the country, the Indian Council of Medical Research has come up with a set of guidelines to regulate their use.

Under the new guidelines, any use of stem cells in patients will be considered research, not therapy.

This means stem cells can now only be used on patients within the purview of an approved, and monitored clinical trial anything outside of this would be considered malpractice. Ananthram Shetty, professor of minimally-invasive surgery at Canterbury Christ Church University, UK, said the guidelines are much-needed, welcome move in the right direction.

Prof. Shetty, who has been working with stem-cell technology for 27 years, and is often in India to demonstrate their use in research surgeries, said this would prevent anybody and everybody from claiming unproven benefits. Lots of people dont really understand what stem cells are. And those who have a terminal illness are willing to try anything. There are some people who use this to raise false hopes. And this is what the guidelines seek to stop, he said.

J.S. Rajkumar, chairman, Lifeline Hospital, however, said the guidelines could have been clearer about the use of adult stem cells over embryonic stem cells, he said. Now, the procedures involved and the time it would take could dissuade many, he said, while there is a real need for funds to be pumped in for research into this technology.

Another International Ear Care Day passed by on March 3.

It spelled out a clear message ear care can avoid hearing loss.

But the question is how many people know how to take care of their ears. What is interesting is the ear is a self-cleaning organ and does not require any kind of cleaning. But many clean their ears using safety pins, hair pins and even matchsticks.

While doctors advise against the use of such objects, they discourage the use of cotton buds too. Some heat coconut oil and pour into the ears. This could cause fungal infections. The ear drum is very thin and can be damaged, leading to loss of hearing, said M. Ramaniraj, professor of ENT, Government Stanley Medical College Hospital.

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Guidelines on use of stem cell therapy

Stem Cell Therapies for Leukemia: Marching Toward the Clinic
Join California #39;s Stem Cell Agency (CIRM) for a live Google Hangout about recent progress in stem cell based treatment strategies for leukemia. Guest experts...

By: California Institute for Regenerative Medicine

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Stem Cell Therapies for Leukemia: Marching Toward the Clinic - Video

21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(Before)
Patient with T5-6 spinal cord injury: condition before treatment Before treatment, sensation remains only above the waist. Sweating remains only in the upper...

By: Cells Center China

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21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(Before) - Video

See Inside Mar 19, 2013 |By Christine Gorman

Richard Clark, NIH

Researchers are now experimenting with stem cellsprogenitor cells that can develop into many different types of tissueto coax the bodies of a few individuals to heal themselves. Some of the most advanced clinical trials so far involve treating congestive heart disease and regrowing muscles in soldiers who were wounded in an explosion. But new developments are happening so quickly that investigators have come up with a new nameregenerative medicineto describe the emerging field.

Many of the stem cells being studied are referred to as pluripotent, meaning they can give rise to any of the cell types in the body but they cannot give rise on their own to an entirely new body. (Only the earliest embryonic cells, which occur just after fertilization, can give rise to a whole other organism by themselves.) Other stem cells, such as the ones found in the adult body, are multipotent, meaning they can develop into a limited number of different tissue types.

One of the most common stem cell treatments being studied is a procedure that extracts a few stem cells from a person's body and grows them in large quantities in the laboratorywhat scientists refer to as expanding the number of stem cells. Once a sufficient number have been produced in this manner, the investigators inject them back into the patient.

The bone marrow is a rich source of adult stem cells, containing both the hematopoietic stem cells that give rise to the various types of blood and the so-called mesenchymal cells, which can develop into bone, cartilage and fat. Mesenchymal cells are found in the bone marrow and various other places in the body, although whether all mesenchymal stem cells are truly interchangeable irrespective of origin is unclear.

Scientific American spoke with Mahendra Rao, director of the Center for Regenerative Medicine at the National Institutes of Health in Bethesda, Md., to get a sense of the sorts of new developments that might occur in regenerative medicine in the next five years or so.

[An edited transcript of the interview follows.]

Why is there so much excitement about regenerative medicine? You could say that medicine up until now has been all about replacements. If your heart valve isn't working, you replace it with another valve, say from a pig. With regenerative medicine, you're treating the cause and using your own cells to perform the replacement. The hope is that by regenerating the tissue, you're causing the repairs to grow so that it's like normal.

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What's Next for Stem Cells and Regenerative Medicine?

Celltex Therapeutics of Houston ceased treatment patients in the U.S. last year after a warning from regulators, and will now send patients for treatments to Mexico

Flickr/GE Healthcare

US citizens who had pinned their hopes on a company being able to offer stem-cell treatments close to home will now need to travel a little farther. Celltex Therapeutics of Houston, Texas, stopped treating patients in the United States last year following a warning from regulators. A 25 January e-mail to Celltex customers indicates that the firm will now follow in the footsteps of many other companies offering unproven stem-cell therapies and send its patients abroad for treatment but only to Mexico.

The stem-cell treatments offered by Celltex involved extracting adult stem cells from a patient, culturing them and then reinjecting them in a bid to replenish damaged tissue. It had been offering the treatment for more than a year with one of its high-profile customers being Texas governor, Rick Perry when the US Food and Drug Administration (FDA) wrote to the company on 24 September 2012 advising it that the stem cells it harvested and grew were more than minimally manipulated during Celltex's procedures. As such, the FDA regarded the cells as drugs, which would require the agency's approval to be used in treatments. The FDA also warned that Celltex had failed to address problems in its cell processing that inspectors from the agency had identified in an April 2012 inspection of its cell bank in Sugar Land, Texas. Shortly after it received the letter, Celltex stopped injecting stem cells into patients.

For customers who still had cells banked at Celltex and were wondering how to get them out, things became more chaotic when Celltex and RNL Bio, a company based in Seoul, South Korea, which operated the processing center and bank in Sugar Land, sued each other over financial disagreements. Celltex had to issue a restraining order just to gain access to the cells.

The January e-mail from Celltex reassures customers that their cells are safely stored in a facility in Houston and adds: We anticipate that we will be able to offer our stem cell therapy services to physicians in Mexico starting very soon! The e-mail also says that the company is building a new laboratory in Houston, to be opened in March.

Celltex adds that it will carry out an FDA-approved clinical trial, to start shortly after a March meeting with the FDA, pending a positive review from the regulator. However, the company had said in a 25 October e-mail to patients that it would start such a trial within two months and that patient enrolment could begin in late November.

Leigh Turner, a bioethicist at the University of Minnesota in Minneapolis, says that the move to Mexico is "not surprising", given the companys difficulties in the United States.

As Celltex's stem culturing and banking technology was licensed from RNL Bio, it is also not clear whether it has the expertise needed to launch a clinical trial on its own, says Turner. "It would have to build a stem-cell company from the ground floor up. I wouldnt say it is anywhere near the starting line."

Celltex did not respond to questions about how it would ship stem cells to Mexico or how it would perform the clinical research needed to seek FDA approval.

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Controversial Stem Cell Company Moves Treatment out of U.S.

RSCI Don Margolis Stem Cells 101 #01
How stem cells treat disease.

By: Repair Stem Cells

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RSCI Don Margolis Stem Cells 101 #01 - Video

stem cell therapy treatment for Spastic Diplegic cerebral palsy by dr alok sharma, mumbai, india
improvement seen in just 5 days after stem cell therapy treatment for Spastic Diplegic cerebral palsy by dr alok sharma, mumbai, india. Stem Cell Therapy don...

By: Neurogen Brain and Spine Institute

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stem cell therapy treatment for Spastic Diplegic cerebral palsy by dr alok sharma, mumbai, india - Video

The California Institute for Regenerative Medicine is rethinking its rules in the wake of a recent breakthrough involving the creation of stem cell lines from a cloned human embryo

OHSU Photos

The announcement last month of a long-awaited breakthrough in stem-cell research the creation of stem-cell lines from a cloned human embryo has revived interest in using embryonic stem cells to treat disease. But US regulations mean that many researchers will be watching those efforts from the sidelines.

The US National Institutes of Health (NIH), which distributes the majority of federal funding for stem-cell research, prohibits research on cells taken from embryos created solely for research a category that includes the six stem-cell lines developed by Shoukhrat Mitalipov, a reproductive-biology specialist at the Oregon Health and Science University in Beaverton, and his colleagues. The team used cloning techniques to combine a donor cell with an unfertilized egg whose nucleus had been removed, creating a self-regenerating stem-cell colony that is genetically matched to the cell donor.

Mitalipovs cell lines are also off limits to researchers funded by the California Institute for Regenerative Medicine (CIRM), which was created in part to support stem-cell work that is restricted by the NIH. CIRM funds cannot be used for studies that pay women for their eggs or rely on cell lines produced using eggs from paid donors. That rules out Mitalipovs lines, because his team paid egg donors US$3,0007,000 each, says Geoffrey Lomax, senior officer to the standards working group at CIRM, which is based in San Francisco. That amount is above and beyond any out-of-pocket costs to donors, he says.

The end result, says Mitalipov, is that a dozen or so universities are struggling to negotiate material transfer agreements to receive the new cell lines without running afoul of CIRM or the NIH. Interest in the new cell lines is high, especially since the identification of errors in images and figures in Mitalipovs research paper shortly after its publication in Cell. But regulations would require laboratories to use only dedicated, privately funded equipment to study the new cells, a condition that only a fewresearchers such as George Daley, a stem-cell expert at Boston Childrens Hospital in Massachusetts will be able to meet.

That concerns Daley, who calls the NIH stem-cell policy a frustrating limitation that will preclude federal dollars being used to ask many important questions about how Mitalipovs cell lines compare with induced pluripotent stem cells (iPS), which are created by reprograming adult cells to an embryonic state. Most labs will take the path of least resistance and continue working with iPS cells unless someone shows that there is a clear and compelling reason to change course, Daley says.

Mitalipov also worries that his cell lines wont be sufficiently analyzed, which he says could hamper efforts to understand how epigenetic changes modifications to chromosomes that determine how genes are expressed affect stem cells' ability to transform into a wide array of mature cell types. We just dont have that much expertise at looking at all aspects of epigenetics, he says.

But some scientists say that the impact of US stem-cell restrictions is overestimated. Alexander Meissner, a developmental biologist at the Harvard Stem Cell Institute in Cambridge, Massachusetts, says Mitalipov's cell lines will not reveal much about how stem cells transform. That work can be done only with eggs that are easy to come by, allowing scientists to examine the reprograming process at many points. In practical terms, that means relying on eggs from mice instead of humans. Everything is over by time you derive those cell lines, he says of Mitalipovs cells. There is no signature that would tell you what has happened. Its the wrong species.

In the meantime, CIRM is re-examining the rules that govern the research its supports. The institute is not likely to alter the restrictions against funding studies that pay cell donors, but it might overturn the rules against using cell lines produced in such studies, Lomax says. The original policy was set in 2006 to address concerns that arose in the wake of fraud and ethical violations by Woo Suk Hwang, then a researcher at Seoul National University.

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Scientists Chafe at Restrictions on New Stem Cell Lines

regenerative medicine - How Stem Cells Fight Aging - Adult Stem Cells
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regenerative medicine - How Stem Cells Fight Aging - Adult Stem Cells - Video

stem cell therapy treatment for Cerebral Palsy with Mental Retardation by dr alok sharma, mumbai
improvement seen in just 5 daysafter stem cell therapy treatment for Cerebral Palsy with Mental Retardation by dr alok sharma, mumbai, india. Stem Cell Thera...

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stem cell therapy treatment for Cerebral Palsy with Mental Retardation by dr alok sharma, mumbai - Video

RSCI Don Margolis Stem Cells 101 #02
The difference between Embryonic and Repair Stem Cells.

By: Repair Stem Cells

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RSCI Don Margolis Stem Cells 101 #02 - Video

BBQ2d Ethical Issues Related to Stem Cell Therapy
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By: Emily DeMarco

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BBQ2d Ethical Issues Related to Stem Cell Therapy - Video

Experience and expertise run in the genes of this doctor, a third-generation fresh cell therapy practitioner

It was a pleaseant, winter morning in Edenkoben, Germany and a group of 15 people from various countries such as Indonesia, the Philippines, Italy, and Germany congregated for breakfast in a coffee shop in this quaint city. Most of these people just flew in from their respective countries, or drove in from different European cities.

But they were not there for an international conference. They were all there for their shots of fresh cell from Dr. Robert Janson-Mueller.

For the past couple of years, through his solo practice, Dr. Robert Mueller has been sharing the benefits of fresh cell therapy with people who need to seek alternative means to remedy various diseases or chronic conditions of their body, or anti-aging solutions.

Although Filipinos has heard of stem cell therapy only in recent years, thanks to celebrities and politicians who have undergone the treatment and do swear by its efficacy, fresh cell therapy has been around since the 1930s.

The Swiss doctor Prof. Paul Niehans first injected cells originating from animal organs intramuscular into patients in 1931 and is thus considered the founder of live cell therapy. Dr. Robert Muellers grandfather, Dr. Philipp Janson, was one of the first doctors to introduce this method in Germany in 1949. His father, Dr. Wolfgang Janson-Meller, also extensively practiced for 35 years.

Since the 90s, I have been able to participate in the wealth of experience that my father, who is always available for help and advice, has gladly passed on to me. I have been using this method of treatment in my own practice since 2003, says Dr. Mueller.

However, the 47-year old doctor differentiates his practice from others (there are only five known doctors who do fresh cell therapy in Germany) because his clinic tailor-fits the fresh cell injections according to the specific needs of the individuals body. A patient thus gets from about eight to 30 injections, depending on the needs.

In this interview with Dr. Mueller, the German expert sheds more light on this therapy that is attracting more and more Filipinos as an alternative treatment. He also explains why fresh cell therapy is not a cure-all or a miracle therapy, why cells from the sheep embryo is being used, why the treatment is becoming popular in Asia, and why it is not possible, up to now, that these therapies can be done in the Philippines.

For more information on fresh cell therapy, visit the website http://www.janson-mueller.de or call Joey Santos at 0917898-6564 or 633-8653.

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Cracking the fresh cell code

Orange County, CA (PRWEB) March 03, 2014

The top stem cell treatment clinic in Southern California, Telehealth, is now offering several knee pain treatment options for avoiding joint replacement. The regenerative medicine treatments involve either platelet rich plasma therapy, bone marrow derived stem cell injections or blood derived stem cell treatment. Call for more information and scheduling call (888) 828-4575. The treatments may be completely or partially covered by insurance.

Although knee replacement procedures have been exceptionally successful for reducing one's pain and improving functional abilities, there are some risks associated with the procedure, along with the fact they are not meant to last forever. Unlike conventional nonoperative treatments, such as steroid injections, regenerative medicine treatments maintain the ability to repair and regenerate arthritic tissue as opposed to simply masking pain.

The Board Certified doctors at Telehealth have extensive experience and regenerative medicine therapies for degenerative arthritis of the knee. Stem cell therapy for arthritis has been shown in several small published studies to provide excellent pain relief and maintain cartilage in the knee.

All of the treatments provided are low-risk and outpatient. They involve blood or bone marrow from the patient him or herself, which reduces the risk profile even more.

Telehealth Medical Group has two locations in Southern California. One is right in Santa Ana, while the other is in Upland. Appointments are readily available. Call for more information and scheduling to (888) 828-4575.

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Southern California Stem Cell Clinic, Telehealth, Now Offering Several Knee Treatment Options to Avoid Joint Replacement

Stem Cell Injections in Knee May Improve Response to Medial Meniscectomy A Study Finds
Please like, subscribe, comment and share! ARTICLE http://jbjs.org/article.aspx?articleid=1809954 The objectives were to evaluate the safety of intra-articul...

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Stem Cell Injections in Knee May Improve Response to Medial Meniscectomy A Study Finds - Video