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10. Treat Cerebral Palsy and Epilepsy with Stem Cells (before) – Video

December 21st, 2013 3:42 pm


10. Treat Cerebral Palsy and Epilepsy with Stem Cells (before)
Cerebral palsy is a non-progressive disease, that is, it will be steady as the growth of children. However, epilepsy is a progressive disease. It will be wor...

By: Cells Center China

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10. Treat Cerebral Palsy and Epilepsy with Stem Cells (before) - Video

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Baby Teeth Stem Cells Medical Course – Video

December 21st, 2013 3:42 pm


Baby Teeth Stem Cells Medical Course
For Educational Use Only - Fair Use - Doctors have been harvesting stem cells from umbilical cords for years however recent research shows that baby teeth th...

By: Abiezer Abigail

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Speakiing better and feeling stronger since stem cells – Video

December 21st, 2013 3:42 pm


Speakiing better and feeling stronger since stem cells
Just proving to myself I am speaking better lol.

By: Jayne Thomas

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Speakiing better and feeling stronger since stem cells - Video

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9. Stem Cells for Different Types of Cerebral Palsy in Children(before) – Video

December 20th, 2013 2:43 am


9. Stem Cells for Different Types of Cerebral Palsy in Children(before)
Generally speaking, there are five types of cerebral palsy in children. We will make specific treating plan to each patient according to their real illness c...

By: Cells Center China

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Democracy 3: United Kingdom – "Stem Cells Are Cool" [Part #5] – Video

December 20th, 2013 2:43 am


Democracy 3: United Kingdom - "Stem Cells Are Cool" [Part #5]
Elected Prime Minister after his party promised that they wouldn #39;t pass internet censorship, The ConflictNerd must now take the United Kingdom to new heights...

By: ConflictNerd

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Democracy 3: United Kingdom - "Stem Cells Are Cool" [Part #5] - Video

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Stem Cells for MS update – Video

December 20th, 2013 2:43 am


Stem Cells for MS update
December 18, 2013 My 2nd infusion of this treatment....feeling fine.

By: Judi Lecoq

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Stem Cells for MS update - Video

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Rudolf Jaenisch – Induced pluripotent stem cells – Video

December 20th, 2013 2:43 am


Rudolf Jaenisch - Induced pluripotent stem cells
Serious Science - http://serious-science.org.

By: SeriousScience

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Stem Cell Therapy – Facet Syndrome Patients Relieve Back and Neck Pain Dr Robert Wagner – NSPC – Video

December 20th, 2013 2:41 am


Stem Cell Therapy - Facet Syndrome Patients Relieve Back and Neck Pain Dr Robert Wagner - NSPC
How to know if the cause of your back or neck pain is Facet Syndrome. Discover how biologic regenerative treatments are able to pick up where traditional tre...

By: StemCell Arts

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Stem Cell Therapy - Facet Syndrome Patients Relieve Back and Neck Pain Dr Robert Wagner - NSPC - Video

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Stem Cell Therapy by Vet-Stem, a Surprising Alternative to Hip Surgery for a New Jersey Chocolate Labrador Retriever

December 19th, 2013 10:41 pm

Poway, CA (PRWEB) December 19, 2013

Amazing Grace Hamiltons banked stem cells from Vet-Stem, Inc. have recently helped her avoid hip surgery for the second time. Gracie is now nearly 12 years old and her owners noticed her activities had dramatically slowed in the last year. They turned to banked stem cells that Gracie had stored with Vet-Stem, Inc. in Poway, California to help with the discomfort and pain of arthritis that was slowing her down.

When Gracies owners brought her to Garden State Veterinary Specialists in Tinton Falls, New Jersey in October of this year the x-rays showed a severely deteriorated right hip. Dr. Thomas Scavelli and Dr. Michael Hoelzler were very concerned and recommended hip replacement. Gracies owners wanted to try stem cell therapy first, since it had given them such positive results five years before.

We needed to give the stem cells a try before going to the more invasive surgical approach, Mrs. Hamilton said. At the time of the procedure Dr. Hoelzler told me that Gracies hips were the worst he had seen, but in just a couple of days after the stem cell therapy we began to see a difference. Just shy of two weeks after the procedure I took her back to Dr. Hoelzler and he was very impressed. She was walking comfortably.

At three years Gracie had been diagnosed with hip dysplasia. By six years of age she had slowed to the point of great concern as her owners described it. The pain caused by arthritis from the hip dysplasia was beginning to interfere with her life.

Gracie was no longer running and jumping, and certain activities had become difficult (like climbing onto my husbands sailboat). She also had a noticeable limp, Mrs. Hamilton remembered the signs of pain and discomfort that prompted Gracies first stem cell therapy five years before.

Gracie was brought to Dr. Scavelli in 2008 with painful symptoms, and stem cell therapy for pets was the latest, cutting edge treatment. Gracies owners understood that without stem cell therapy Gracie would have faced hip surgery at the time.

We are grateful for stem cell therapy which has restored Gracies ability to enjoy her morning walks again, Mrs. Hamilton shared, She enjoys wrestling with us and playing with her toys. She looks forward to visiting her friends, and prances around like a puppy. Gracie is a happy dog and we are happy owners because she does not appear to be in pain anymore!

About Vet-Stem, Inc.

Vet-Stem, Inc. was formed in 2002 to bring regenerative medicine to the veterinary profession. The privately held company is working to develop therapies in veterinary medicine that apply regenerative technologies while utilizing the natural healing properties inherent in all animals. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem, Inc. pioneered the use of regenerative stem cells in veterinary medicine. The company holds exclusive licenses to over 50 patents including world-wide veterinary rights for use of adipose derived stem cells. In the last decade over 10,000 animals have been treated using Vet-Stem, Inc.s services, and Vet-Stem is actively investigating stem cell therapy for immune-mediated and inflammatory disease, as well as organ disease and failure. For more on Vet-Stem, Inc. and Veterinary Regenerative Medicine visit http://www.vet-stem.com or call 858-748-2004.

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Stem Cell Therapy by Vet-Stem, a Surprising Alternative to Hip Surgery for a New Jersey Chocolate Labrador Retriever

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Adult Stem Cells Found to Suppress Cancer While Dormant

December 18th, 2013 1:42 pm

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Available for logged-in reporters only

Newswise Researchers at UCLAs Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered a mechanism in adult stem cells by which the cells suppress their ability to initiate cancer during their dormant phase, an understanding that could be exploited for better cancer prevention strategies. The study was led by Andrew White, post-doctoral fellow, and William Lowry, associate professor of molecular, cell and developmental biology in the life sciences and the Maria Rowena Ross Term Chair in Cell Biology.

The study was published online ahead of print in Nature Cell Biology on December 15, 2013.

Hair follicle stem cells (HFSC), the tissue-specific adult stem cells that generate the hair follicles, are also the cells of origin for cutaneous squamous cell carcinoma (SCC), a common skin cancer. These HFSCs cycle between periods of activation, during which they can grow, and quiescence, when they remain dormant.

Using mouse models, White and Lowry applied known cancer-causing genes (oncogenes) to HFSCs and found that during cell quiescence, the cells could not be made to initiate SCC. Once the HFSC were in their active period, they began growing cancer.

We found that this tumor suppression via adult stem cell quiescence was mediated by Pten, a gene important in regulating the cells response to signaling pathways, White said, therefore, stem cell quiescence is a novel form of tumor suppression in hair follicle stem cells, and Pten must be present for the suppression to work.

Understanding cancer suppression through quiescence could better inform preventative strategies in patients susceptible to SCC, such as organ transplant patients, or those taking the drug vemurafenib for melanoma, another type of skin cancer. This study also may reveal parallels between SCC and other cancers in which stem cells have a quiescent phase. This research was supported by the California Institute of Regenerative Medicine (CIRM), University of California Cancer Research Coordinating Committee (CRCC) and National institutes of Health (NIH).

The stem cell center was launched in 2005 with a UCLA commitment of $20 million over five years. A $20 million gift from the Eli and Edythe Broad Foundation in 2007 resulted in the renaming of the center. With more than 200 members, the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research is committed to a multi-disciplinary, integrated collaboration of scientific, academic and medical disciplines for the purpose of understanding adult and human embryonic stem cells. The center supports innovation, excellence and the highest ethical standards focused on stem cell research with the intent of facilitating basic scientific inquiry directed towards future clinical applications to treat disease. The center is a collaboration of the David Geffen School of Medicine, UCLAs Jonsson Comprehensive Cancer Center, the Henry Samueli School of Engineering and Applied Science and the UCLA College of Letters and Science. To learn more about the center, visit our web site at http://www.stemcell.ucla.edu.

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Adult Stem Cells Found to Suppress Cancer While Dormant

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Will stem cell therapy help cure spinal cord injury?

December 18th, 2013 1:42 pm

Dec. 17, 2013 A systematic survey of the scientific literature shows that stem cell therapy can have a statistically significant impact on animal models of spinal cord injury, and points the way for future studies.

Spinal cord injuries are mostly caused by trauma, often incurred in road traffic or sporting incidents, often with devastating and irreversible consequences, and unfortunately having a relatively high prevalence (250,000 patients in the USA; 80% of cases are male). High-profile campaigners like the late actor Christopher Reeve, himself a victim of sports-related spinal cord injury, have placed high hopes in stem cell transplantation. But how likely is it to work?

This question is addressed in a paper published 17th December in the open access journal PLOS Biology by Ana Antonic, David Howells and colleagues from the Florey Institute and the University of Melbourne, Australia, and Malcolm MacLeod and colleagues from the University of Edinburgh, UK.

Stem cell therapy aims to use special regenerative cells (stem cells) to repopulate areas of damage that result from spinal cord injuries, with the hope of improving the ability to move ("motor outcomes") and to feel ("sensory outcomes") beyond the site of the injury. Many studies have been performed that involve animal models of spinal cord injury (mostly rats and mice), but these are limited in scale by financial, practical and ethical considerations. These limitations hamper each individual study's statistical power to detect the true effects of the stem cell implantation.

This new study gets round this problem by conducting a "meta-analysis" -- a sophisticated and systematic cumulative statistical reappraisal of many previous laboratory experiments. In this case the authors assessed 156 published studies that examined the effects of stem cell treatment for experimental spinal injury in a total of about 6000 animals.

Overall, they found that stem cell treatment results in an average improvement of about 25% over the post-injury performance in both sensory and motor outcomes, though the results can vary widely between animals. For sensory outcomes the degree of improvement tended to increase with the number of cells introduced -- scientists are often reassured by this sort of "dose response," as it suggests a real underlying biologically plausible effect.

The authors went on to use their analysis to explore the effects of bias (whether the experimenters knew which animals were treated and which untreated), the way that the stem cells were cultured, the way that the spinal injury was generated, and the way that outcomes were measured. In each case, important lessons were learned that should help inform and refine the design of future animal studies. The meta-analysis also revealed some surprises that should provoke further investigation -- there was little evidence of any beneficial sensory effects in female animals, for example, and it didn't seem to matter whether immunosuppressive drugs were administered or not.

The authors conclude: "Extensive recent preclinical literature suggests that stem cell-based therapies may offer promise; however the impact of compromised internal validity and publication bias means that efficacy is likely to be somewhat lower than reported here."

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Will stem cell therapy help cure spinal cord injury?

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Regenerative Medicine: Mayo Clinic and Collaborators Develop New Tool for Transplanting Stem Cells – Video

December 18th, 2013 2:46 am


Regenerative Medicine: Mayo Clinic and Collaborators Develop New Tool for Transplanting Stem Cells
Mayo Clinic researchers and colleagues in Belgium have developed a specialized catheter for transplanting stem cells into the beating heart. The novel device...

By: Mayo Clinic

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Regenerative Medicine: Mayo Clinic and Collaborators Develop New Tool for Transplanting Stem Cells - Video

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With new multimillion-dollar grants, UCLA scientists take stem cell research to patients

December 17th, 2013 12:42 pm

PUBLIC RELEASE DATE:

16-Dec-2013

Contact: Shaun Mason smason@mednet.ucla.edu 310-206-2805 University of California - Los Angeles

Scientists from UCLA are now bringing their groundbreaking stem cell science directly to patients in two exciting new clinical trials scheduled to begin in early 2014, thanks to funding from California's stem cell agency.

The new grants to researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, which total nearly $21 million, were announced Dec. 12 at a meeting of the California Institute of Regenerative Medicine (CIRM) Citizen's Oversight Committee. They are apart of the state agency's Disease Team Therapy Development III initiative.

A team led by UCLA's Dr. Dennis Slamon and Dr. Zev Wainberg was awarded nearly $7 million for a clinical trial that will test a new drug targeting cancer stem cells, and UCLA's Dr. Donald Kohn received almost $14 million for a clinical trial that will focus on stem-cell gene therapy for sickle cell disease.

"The CIRM support demonstrates that our multidisciplinary center is at the forefront of translating basic scientific research into new drug and cellular therapies that will revolutionize medicine," said Dr. Owen Witte, director of the UCLA Broad Stem Cell Research Center.

Dennis Slamon and Zev Wainberg: Targeting solid tumor stem cells

This clinical trial builds on Slamon's previous work, partially funded by CIRM, with Wainberg and Dr. Tak Mak, director of the Campbell Family Institute at the University Health Network in Toronto, aimed at developing a drug that targets those stem cells thought to initiate solid cancer tumors.

The AmericanCanadian collaborative team will lead this first in-human Phase 1 trial testing their new therapy, which has received investigational new-drug approval from the U.S. Food and Drug Administration and Health Canada, Canada's therapeutic regulatory agency. The project has been approved to begin enrolling patients in both the U.S. and Canada.

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With new multimillion-dollar grants, UCLA scientists take stem cell research to patients

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Stem Cells and You – Video

December 17th, 2013 4:44 am


Stem Cells and You
Education on Stem Cells.

By: Andrew Trybull

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Stem Cells and You - Video

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3. Treat Cerebral Palsy Children with Stem Cells (after treatment) – Video

December 17th, 2013 4:44 am


3. Treat Cerebral Palsy Children with Stem Cells (after treatment)
With the development of medical technology, there are still many cerebral palsy children all over the world. Zhe Zhe, male, 5 years old. He was admitted for ...

By: Cells Center China

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3. Treat Cerebral Palsy Children with Stem Cells (after treatment) - Video

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Stem cells therapy in Mexico Testimony-Carmen1 – Video

December 17th, 2013 4:44 am


Stem cells therapy in Mexico Testimony-Carmen1
http://a1stemcells.com Testimony after 5 embryonic stem cells IV injections for a rejuvenation study.

By: Cure4Cancers

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Stem cells therapy in Mexico Testimony-Carmen1 - Video

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Stem cells and ccsvi, step 2 – Video

December 16th, 2013 11:43 am


Stem cells and ccsvi, step 2
Finally made it to Newport Beach to meet Dr. Arata!

By: Judi Lecoq

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Stem cells and ccsvi, step 2 - Video

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1. PHAM After the First Course Stem Cells Treatment (after) – Video

December 16th, 2013 11:43 am


1. PHAM After the First Course Stem Cells Treatment (after)
PHAM, 3-year-old boy, Cerebral Palsy patient. After first stem cells, he can walk alone and steadily. In addition, he is more smart than before. Now, he is p...

By: Cells Center China

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1. PHAM After the First Course Stem Cells Treatment (after) - Video

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1. PHAM Before the First Course Stem Cells Treatment (before) – Video

December 16th, 2013 11:43 am


1. PHAM Before the First Course Stem Cells Treatment (before)
Before the first stem cells treatment, PHAM can not walk and stand. Cerebral Palsy.

By: Cells Center China

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1. PHAM Before the First Course Stem Cells Treatment (before) - Video

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Rejection… is it a problem with stem cell arthritis treatment? – Video

December 16th, 2013 11:41 am


Rejection... is it a problem with stem cell arthritis treatment?
http://www.stemcellsarthritistreatment.com Stem cells may not be rejected... here #39;s why it #39;s important for arthritis treatment... Ryan and colleagues in an a...

By: Nathan Wei

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Rejection... is it a problem with stem cell arthritis treatment? - Video

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