StemCell Therapy

The ankylosing spondylitis and psoriatic arthritis markets are growing increasingly crowded, but Novartis now has something not all its rivals can boast: long-term data for its IL-17 med, Cosentyx.

Thursday at the Annual European Congress of Rheumatology in Madrid, the Swiss drugmaker unveiled study results showing its contender could show sustained improvements in signs and symptoms of both maladies.

In one extension trial, at three years, 80% of ankylosing spondylitis patients taking Cosentyx hit the 20 mark on the Assessment of Spondyloarthritis International Society response criteria scale.

And a new analysis of Novartis Future 2 study showed that by the two-year point, 28% of psoriatic arthritis patients treated with Cosentyxalmost all of whom had reported moderate-to-extreme pain or discomfort before starting on the drugfelt no pain or discomfort at all.

RELATED:Novartis extends lead on psoriasis rivals with a pair of new Cosentyx approvals

Its good news for Novartis, whose med is currently the only member of the IL-17 crowd to boast indications in ankylosing spondylitis and psoriatic arthritis. Knowing competition was on the way, the company worked to snag those a year after winning Cosentyx initial nod in psoriasis.

Since then, Novartis has been joined by Eli Lillys Taltz and Valeants Siliq, and development of other candidatessuch as Johnson & Johnsons guselkumabis underway. Lilly, for one, currently has Taltz in phase 3 as a treatment for axial spondyloarthritis, an umbrella that includes ankylosing spondylitis.

But its not only IL-17 products competing for a slice of the pie. Pfizer is developing its rheumatoid arthritis pill, Xeljanz, for psoriatic arthritis, and Celgene's psoriasis pill Otezla has a psoriatic arthritis nod, as well. On the ankylosing spondylitis front, J&Js Stelara could eventually challenge Cosentyx, research and consulting firm GlobalData has predicted.

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Novartis' Cosentyx racks up more long-term data in psoriatic arthritis and ankylosing spondylitis - FiercePharma

This entry was posted on June 15, 2017 at 9:44 pm and is filed under Arthritis. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed. |