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Question: I have an old mixed-breed dog that has had arthritis for years and it has gotten to the point where he needs my help to get up off the floor. It is getting very hard for me to lift him. He took many different NSAIDS in his life, but now his kidneys and liver are not good, so we decided to take him off of those since they can cause more damage. We tried Tramadol and Gabapentin, but they did not help and just made him loopy. I read about a new drug for dogs called Galliprant. I asked my vet about it but he did not know anything. Would it help my Snoopy without hurting him?

Answer: It is not uncommon for dogs to have deteriorating kidney and liver function as they age. They often have stiff, aching joints as well.

We have been blessed with many good NSAIDs (non-steroidal anti-inflammatory drugs) to help decrease inflammation and pain. These drugs have been lifesavers for many dogs, and have allowed them to live longer happier lives. Unfortunately, they do have limitations and can cause gastrointestinal issues, like ulcers or vomiting, but more importantly, they are filtered through the kidneys and liver, and complications can develop if the function of these organs are compromised. This is why routine blood testing is mandatory when your dog is taking NSAIDS.

Galliprant is a new class of non-COX inhibiting NSAID medications that are used to treat osteoarthritis pain in dogs. Plumbs Veterinary formulary says: It could potentially cause significantly fewer severe adverse effects in dogs than other NSAIDS. The main side effect is diarrhea or vomiting.

Since Galliprant is a new class of osteoarthritis medication, long-term experience is somewhat limited. Most patients that have been placed on it long term are elderly dogs that have failed all other alternatives. Most owners report that their dogs response to the medication has been very good especially with the response in their dogs comfort level and increased mobility. I would feel very comfortable using this medication on my elderly dog.

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New drug Galliprant a good option for elderly dogs with arthritis - Palm Beach Post

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