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T.G. Nagaraja, distinguished professor of veterinary microbiology at Kansas State University, has been named the 2019 Distinguished Veterinary Microbiologist of the Year by the American College of Veterinary Microbiologists. This award was presented at the organizations annual meeting Nov. 4 in Chicago.

I am truly humbled by the award, Nagaraja said. It is special because this recognition is from my peers. I have had a lot of help in my research career some outstanding graduate students, very good laboratory help and excellent collaborators.

Nagaraja is a member of the diagnostic medicine and pathobiology department faculty in the K-State College of Veterinary Medicine. His appointment is 70% research and 30% teaching. His research expertise is in gut microbiology, focused primarily on the role of rumen microbes in function and dysfunction of the rumen, and on foodborne pathogens, particularly Shiga toxin-producing Escherichia coli and salmonella in cattle. His research is a blend of basic and applied studies and involves collaborative interactions with epidemiologists, molecular biologists, pathologists and ruminant nutritionists.

Included in Nagarajas teaching responsibilities are veterinary bacteriology, and mycology lecture and laboratory for sophomore Doctor of Veterinary Medicine students, ruminant digestive physiology for freshman Doctor of Veterinary Medicine students and two graduate courses, rumen metabolism and rumen microbiology. Additional responsibilities include serving as the College of Veterinary Medicines director of the graduate programs in pathobiology and veterinary biomedical science.

Nagaraja and his graduate students have been responsible for several seminal findings, including describing that the feeding of distillers grain was positively associated with prevalence of E. coli O157, a major foodborne human pathogen, in cattle. In addition, he and his associates were the first to identify and describe the role and importance of the toxin leukotoxin, produced by Fusobacteroum necrophorum that causes liver abscesses in cattle. Nagarajas group also developed an experimental model to study liver abscess in cattle by inoculating F. necrophorum via ultrasound-guided, percutaneous catheterization of the portal vein, which allowed for the demonstration that leukotoxinis can be used to protect the animal against liver abscesses. This led to the development of a U.S. Department of Agriculture-licensed leukotoxoid-based vaccine to prevent liver abscesses in feedlot cattle.

In addition, Nagaraja has developed experimental models to induce bloat and acidosis, two major digestive problems in cattle. The experimental models were instrumental for testing and identifying new compounds to control bloat and acidosis in feedlot cattle, describing the effects of antibiotics like lasalocid, monensin and virginiamycin on ruminal microbes and fermentation to better understand their modes of action.

Nagaraja and his associates have produced more than 216 peer-reviewed articles, 115 invited national and international presentations, 19 book chapters and 20 review papers and symposium proceedings on food safety research. As a mentor, he has supervised 19 doctoral students, 21 masters students and four Master of Public Health students. His work has resulted in eight U.S. patents.

Excerpt from:
Nagaraja named Distinguished Veterinary Microbiologist of the Year - Manhattan Mercury

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