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Kidney disease: how could stem cells help? | Eurostemcell

July 5th, 2017 8:41 pm

The kidneys are towards the back of the body, roughly 10 cm above the hipbones and just below the ribcage. They are the bodys filtering units, maintaining a safe balance of fluid, minerals, salts and other substances in the blood. They produce urine to remove waste and harmful substances from the body. They also produce several hormones: erythropoietin (EPO), which acts on the bone marrow to increase the production of red blood cells; calcitriol (active Vitamin D3), which promotes absorption and use of calcium and phosphate for healthy bones and teeth; and the enzyme renin, which is involved in monitoring and controlling blood pressure.

The key working component of the kidney is the nephron.

The nephron - the functional unit of the kidney:The best evidence so far for stem cells in the adult kidney suggests they might be found in the blue area, called the urinary pole.

The nephron is made up of:

Microscope image of kidney tissue showing tubules. One tubule is highlighted to show epithelial cells (blue), cell nuclei (green) and the tubule lumen (dark center).

See the article here:
Kidney disease: how could stem cells help? | Eurostemcell

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