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IIT-M develops oil-based cancer therapy – Times of India

May 10th, 2020 3:42 pm

Researchers from IIT-Madras have developed a clove oil-based emulsion to treat cancer, claiming that the formulation would have enormous scope in the treatment of undifferentiated cancer and can also overcome anti-microbial resistance. The research papers were published recently in the reputed International Journal of Nanomedicine.The researchers, led by professor R Nagarajan, head, department of chemical engineering in IIT Madras, have developed a nano-scale emulsion of clove bud using the spontaneous self-emulsification technique with potent anti-cancer and antibacterial activity. This formulation meets all compliance requirements, they said. According to Nagarajan, while conventional therapies for cancer like radiation, chemotherapy and surgery cause severe damage to normal cells along with other major side-effects, the plant-based essential oils have paved way to devise innovative solutions to these drawbacks of synthetic drugs.The advantages of these emulsions lie in their small droplet size, ease of preparation, optical clarity, good physical stability, improved bio-availability, non-toxicity and non-irritability, said Nagarajan. This formulation would have an enormous scope in the treatment of metastatic cancer. Moreover, the components involved are cost-effective and demonstrate good efficacy, and the technique employed is simple, which is the utmost need for drug development, he said.The team of scientists includes M Joyce Nirmala, post doctoral fellow, Vineet Gopakumar, B Tech student, and Latha Durai, Research Scientistall from IIT-Madras.

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IIT-M develops oil-based cancer therapy - Times of India

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