While more countries around the world continue to acknowledge the potential of CBD, the full biological effects of the cannabinoid are yet to be fully understood. However, some research demonstrates that CBD has anti-inflammatory and immunosuppressive properties.
But what does this mean for those that use CBD products, and who could potentially benefit from it?
CBD is one of the most common chemical compounds found in the cannabis plant. It is classed as a cannabinoid, along with Tetrahydrocannabinol (THC) and Cannabinol (CBN), and over a hundred other compounds in the plant. Cannabinoids are naturally occurring chemicals that have become known for their medicinal and wellness potential.
It is also clear that, in some cases, CBD might be used to treat particular diseases for which other available treatments have failed to be effective. Although we know that it produces effects in the central nervous system, in contrast to THC, which is psychoactive, CBD doesnt create the so-called high feeling.
In a nutshell, the immune system is the main defense our bodies have against diseases and other potentially damaging threats. When functioning properly, the immune system identifies and attacks intruders, such as bacteria, viruses, and parasites distinguishing them from our bodys healthy tissue.
Lymphocytes, or B cells and T cells, fight against antigens and they help the body to remember the once-beaten substances so that the next time the immune system can act quickly and effectively.
Despite the existence of the Endocannabinoid System only being confirmed by researchers in the 1990s, we already know that this system can play an important role in many bodily functions, including brain functions. Endocannabinoid receptors are expressed throughout the central nervous system, as well as in the human immune system.
Interactions between endocannabinoids and receptors are thought to influence mood, emotions, appetite, pain-sensation and memory, among other important physiological and cognitive processes. Phytocannabinoids (the most well-known are CBD and THC) interact with this system in similar ways to endocannabinoids.
According to research by James M. Nichols and Barbara L.F. Kaplan, it would appear that considering all the studies conducted on immune responses and inflammation, the data overwhelmingly demonstrate that CBD is immune suppressive and anti-inflammatory.While the definition of something being anti-inflammatory should be clear, CBD functioning as an immunosuppressant might require clarification.
As a potential immunosuppressant, CBD may reduce the immune systems inflammatory responses, promote apoptosis (cellular death), and prevent rapid cellular growth. In certain cases, these features may have a negative effect on a healthy humans immune system.
In addition, CBD exposure may also suppress the functions of cytokines, chemokines, and T cells all of which play an important role in immunodefense.
It has been suggested that CBD may have potential as an adjunct treatment for some autoimmune diseases.
An autoimmune disease is when the immune system begins to attack healthy cells, tissues, and organs. This can occur basically anywhere in the body, and it can result in particular body functions weakening and, in some cases, life-threatening conditions. The most common autoimmune diseases include Multiple Sclerosis (MS), Rheumatoid Arthritis, and Psoriasis.
Inflammation plays an important role in autoimmune diseases. As an anti-inflammatory,CBD might help the body to tackle the disease. In addition, CBDs immunosuppressive nature might be able to help it to deal with hyperactive immune systems that attack themselves.
Link:
How Does CBD Affect the Immune System and Autoimmune Disease? - The Cannabis Exchange
- Systemic Lupus Erythematosus (Lupus) - Who gets it? | NIAMS - February 7th, 2025
- Systemic Lupus Erythematosus (Lupus) Basics - National Institute of ... - February 7th, 2025
- Long COVID: women at greater risk compared to men could immune system differences be the cause? - The Conversation - February 7th, 2025
- What is Pemphigus? Symptoms & Causes | NIAMS - February 7th, 2025
- How the immune system influences pancreatic cancer: New interactions provide therapeutic insights - Medical Xpress - February 7th, 2025
- Mitochondrias Secret Power Unleashed in the Battle Against Inflammation - SciTechDaily - February 7th, 2025
- WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis - Nature.com - February 7th, 2025
- The role of the behavioral immune system in the expression of short and long-term orientation in young Chilean men during the COVID-19 pandemic - BMC... - February 7th, 2025
- Harvard nutritionist eats these 5 foods to keep her 'immune system strong' and 'energy high' - CNBC - February 7th, 2025
- Micro Immune Response On-chip (MIRO) models the tumour-stroma interface for immunotherapy testing - Nature.com - February 7th, 2025
- Personalized Therapeutic Vaccine Steers the Immune System to Fight Kidney Cancer | Newswise - Newswise - February 7th, 2025
- Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma - Nature.com - February 7th, 2025
- Serotonin attenuates tumor necrosis factor-induced intestinal inflammation by interacting with human mucosal tissue - Nature.com - February 7th, 2025
- Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquidliquid phase separation-related genes - Nature.com - February 7th, 2025
- FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy - Nature.com - February 7th, 2025
- Young Innovators: U of S researcher uses bat immune systems to find next generation therapies - Saskatoon Star-Phoenix - February 7th, 2025
- World Cancer Day 2025: Chronic stress, immune system, and cancer risk- How are these connected? - The Times of India - February 7th, 2025
- New research unlocks key to long-lasting immune response in cancer and chronic diseases - The Peter Doherty Institute for Infection and Immunity - February 7th, 2025
- Microbial Dynamics and Immune Response to NTHi in COPD - Physician's Weekly - February 7th, 2025
- MHE Week in Review RFK Jr. Spotlight - Managed Healthcare Executive - February 7th, 2025
- Psoriasis Basics: Overview, Symptoms, and Causes - January 27th, 2025
- Vitiligo Symptoms, Treatment & Causes | NIAMS - January 27th, 2025
- The Surprising Connection Between Obesity, Parasites, and Your Immune System - SciTechDaily - January 27th, 2025
- Versatile 69p spice that boosts immune system can go in soups, smoothies and milk - Express - January 27th, 2025
- How the skins secret immune system could lead to needle-free vaccines - Gavi, the Vaccine Alliance - January 27th, 2025
- Fevers link with a key kind of immunity is surprisingly ancient - Science News Magazine - January 27th, 2025
- Immunology - The Scientist - January 27th, 2025
- Opinion: Immune System And Ageing Why We Get More Vulnerable As We Age - ABP Live - January 27th, 2025
- 'Forever chemicals' (PFAS) may weaken immune function in children, leading to more frequent infections - U.S. Right to Know - January 27th, 2025
- Cellular Signals That Wreak Havoc in Sepsis are Revealed - LabRoots - January 27th, 2025
- New Combination Immunotherapy Targets Melanoma and Breast Cancer with Promising Results - Inside Precision Medicine - January 27th, 2025
- New Research in The Journal of Poultry Science: Trained Immunity Offers Novel Poultry Disease Prevention Strategies - PR Newswire - January 27th, 2025
- Scientists uncover how cancer cells hijack T-cells, making it harder for the body to fight back - Medical Xpress - January 27th, 2025
- MiNK Therapeutics Targets Immune Reconstitution to Combat - GlobeNewswire - January 27th, 2025
- Mitochondria may be a promising therapeutic target for inflammatory diseases - Medical Xpress - January 27th, 2025
- Explainer: What is Guillain-Barr Syndrome and how it affects the immune system - Mathrubhumi English - January 27th, 2025
- Yes, Some Vaccines Contain Aluminum. Thats a Good Thing. - The New York Times - January 27th, 2025
- You Are What You Eat? MD Breaks Down The Science Of The Gut Microbiome - mindbodygreen - January 27th, 2025
- Potential gamechanger: Researchers discover basis for immunotherapy-induced myocarditis - Healio - January 27th, 2025
- Ozempic and Wegovy may boost health, from addiction to dementia - BBC.com - January 27th, 2025
- Neutrophil diversity and function in health and disease - Nature.com - December 6th, 2024
- Harnessing the Power of the Immune System for Breast Cancer Treatment - Breast Cancer Research Foundation - December 6th, 2024
- Study Examines Neoantigen Landscapes and Their Role in Immunotherapy Efficacy - Consult QD - December 6th, 2024
- The 5 Best Teas to Support Your Immune System This Cold & Flu Season - EatingWell - December 6th, 2024
- Engineered immune cells may be able to tame inflammation - Medical Xpress - December 6th, 2024
- Hybrid model of tumor growth, angiogenesis and immune response yields strategies to improve antiangiogenic therapy - Nature.com - December 6th, 2024
- Opioids interfere with cancer immunotherapy, but another type of drug could help - Medical Xpress - December 6th, 2024
- RANKL cytokine restores thymus cells in old mice, reducing tumor growth and improving T cell immune response - Fierce Biotech - December 6th, 2024
- Predictive role of neutrophil percentage-to-albumin ratio, neutrophil-to-lymphocyte ratio, and systemic immune-inflammation index for mortality in... - December 6th, 2024
- Immuno-Oncology Strategic Industry Research Report 2023-2024 & 2030: Approval of Pembrolizumab (Keytruda) and Nivolumab (Opdivo), which Target... - December 6th, 2024
- Study cracks the cold case of immunotherapy resistance - News-Medical.Net - December 6th, 2024
- New immune therapy improves survival and reduces tumor burden in glioblastoma - News-Medical.Net - December 6th, 2024
- Identification of immune-related hub genes and potential molecular mechanisms involved in COVID-19 via integrated bioinformatics analysis - Nature.com - December 6th, 2024
- Immune Cell Breakthrough: Scientists Discover a Hidden Ally in the Fight Against Cancer - SciTechDaily - December 6th, 2024
- Rising temperatures impact the immune system of wild monkeys - Earth.com - December 6th, 2024
- Study declaring Alzheimer's to be a "brain disease" proven to be fabricated - Earth.com - December 6th, 2024
- Warming temperatures impact immune performance of wild monkeys, U-M study shows - University of Michigan News - December 6th, 2024
- New study explores heart risks of cancer immunotherapy - News-Medical.Net - December 6th, 2024
- 'Incredible' way to boost your immune system naturally and ward of colds and flu this winter - The Mirror - December 6th, 2024
- Tis the Season to Boost Your Immune System - Mix93.3 - December 6th, 2024
- A mathematical model simulating the adaptive immune response in various vaccines and vaccination strategies - Nature.com - October 14th, 2024
- Fox Chase Cancer Center Researchers Find Gene That Triggers Immune Response in Treatment-Resistant Small-Cell Lung Cancer - Fox Chase Cancer Center - October 14th, 2024
- What Does It Mean to Be Immunocompromised? - The New York Times - October 14th, 2024
- Scientist hopes to cure Type 1 diabetes by disguising stem cells - The University of Arizona - October 14th, 2024
- Watching an infection unfold with a sphingolipid probe - Drug Discovery News - October 14th, 2024
- The cells that protect your brain against infection could also be behind some chronic diseases - BBC.com - October 14th, 2024
- On Nutrition: Foods that help strengthen the immune system - LimaOhio.com - October 14th, 2024
- An integral T cell pathway has implications for understanding sex-based immune response - Medical Xpress - October 14th, 2024
- Immune Response Linked to Lewy Body Formation - Neuroscience News - October 14th, 2024
- Are vaccines the future of cancer prevention? - Genetic Literacy Project - October 14th, 2024
- The Gut Microbiome and Autoimmunity - Inside Precision Medicine - October 14th, 2024
- Researchers discover how oral cancer cells may block the body's immune response - News-Medical.Net - September 21st, 2024
- Are Vaccines More Effective When You Believe in Them? - Greater Good Science Center at UC Berkeley - September 21st, 2024
- Researchers discover immune response to dengue can predict risk of severe reinfections - Medical Xpress - September 21st, 2024
- Texas Researchers Find Acid Walls That Shield Cancer Tumors from Bodys Immune System Response - DARKDaily.com - Laboratory News - September 21st, 2024
- Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis - Nature.com - September 21st, 2024
- A new way to reprogram immune cells and direct them toward anti-tumor immunity - MIT News - September 21st, 2024
- Unravelling the many mysteries of the immune system - Cosmos - September 21st, 2024
- Long COVID patients maintain robust immune memory two years after infection - News-Medical.Net - September 21st, 2024
- Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other viral infections - Journal of... - September 21st, 2024