Your immune system is your bodys defense againstinfections and other harmfulinvaders. Without it, you would constantly get sick frombacteria or viruses.
Your immune system is made up of special cells, tissues, and organs that work together to protect you.
The lymph, or lymphatic, system is a major part of the immune system. It's a network of lymph nodes and vessels. Lymphatic vessels are thin tubes that branch, like blood vessels,throughout the body. They carry a clear fluid called lymph. Lymph contains tissue fluid, waste products, and immune system cells. Lymph nodes are small, bean-shaped clumps of immune system cells that are connected by lymphatic vessels. They contain white blood cells that trap viruses, bacteria, and other invaders, including cancer cells.
White blood cells are the cells of the immune system. They are made in one of your lymph organs, the bone marrow. Other lymph organs include thespleen and thymus.
When your immune system doesn't work the way it should, it is called an immune system disorder. You may:
Beborn with a weak immune system. This is called primary immune deficiency.
Get a disease that weakens your immune system. This is called acquired immune deficiency.
Have animmune system that is too active.This may happen with an allergic reaction.
Have animmune system thatturns against you. This is called autoimmune disease.
Here are some common examples:
Severe combined immunodeficiency (SCID).This is an example of an immune deficiency that is present at birth.Children arein constant danger of infections from bacteria, viruses, and fungi. This disorder is sometimes called bubble boy disease.In the 1970s, a boyhad to live in a sterile environment inside a plastic bubble. Children with SCID are missing important white blood cells.
Temporary acquired immune deficiencies.Yourimmune system can be weakened by certain medicines, for example. This canhappen to peopleon chemotherapy or other drugs used to treat cancer. It can also happen to people followingorgan transplants who take medicine to prevent organ rejection.Also, infections like the flu virus, mono (mononucleosis), and measlescan weaken the immune system for a brief time. Your immune system can also be weakened by smoking, alcohol,and poor nutrition.
AIDS.HIV, which causes AIDS, is an acquired viralinfection that destroys important white blood cells and weakens the immune system.People withHIV/AIDS become seriously ill with infections that most peoplecan fight off. These infections are called opportunistic infections because they take advantage of weak immune systems.
If you are born with certain genes, your immune system may react to substances inthe environment that are normally harmless. These substances are called allergens. Having an allergic reaction is the most common example of an overactive immune system. Dust, mold, pollen,and foods are examples of allergens.
Some conditions caused by an overactive immune system are:
Asthma.The response in your lungs can cause coughing, wheezing, and trouble breathing. Asthma can be triggered by common allergens like dust or pollenor by an irritant like tobacco smoke.
Eczema.An allergen causes an itchy rash known as atopic dermatitis.
Allergic rhinitis.Sneezing, a runny nose, sniffling, and swelling of your nasal passages from indoor allergens like dust and pets or outdoor allergens like pollens or molds.
Inautoimmune diseases, the body attacks normal, healthy tissues. The cause is unknown. It is probably a combination of a persons genes and something in the environmentthat triggers those genes.
Three common autoimmune diseases are:
Type 1 diabetes.The immune systemattacksthe cells inthe pancreas that make insulin. Insulin removes sugar fromthe blood to use as energy.
Rheumatoid arthritis.Thistype of arthritiscauses swelling and deformities of the joints. An auto-antibody called rheumatoid factoris in the blood of some people with rheumatoid arthritis.
Lupus.This disease that attacks body tissues, including thelungs, kidneys, and skin. Many types of auto-antibodies are found in the blood ofpeople with lupus.
No one knows exactly what causes autoimmune diseases, but many factors seem to be involved. If you have an immune system disorder, learn as much as you can aboutit. And work closely with yourhealthcare providersto manage it.
Read the original here:
Disorders of the Immune System | Johns Hopkins Medicine
- Systemic Lupus Erythematosus (Lupus) - Who gets it? | NIAMS - February 7th, 2025
- Systemic Lupus Erythematosus (Lupus) Basics - National Institute of ... - February 7th, 2025
- Long COVID: women at greater risk compared to men could immune system differences be the cause? - The Conversation - February 7th, 2025
- What is Pemphigus? Symptoms & Causes | NIAMS - February 7th, 2025
- How the immune system influences pancreatic cancer: New interactions provide therapeutic insights - Medical Xpress - February 7th, 2025
- Mitochondrias Secret Power Unleashed in the Battle Against Inflammation - SciTechDaily - February 7th, 2025
- WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis - Nature.com - February 7th, 2025
- The role of the behavioral immune system in the expression of short and long-term orientation in young Chilean men during the COVID-19 pandemic - BMC... - February 7th, 2025
- Harvard nutritionist eats these 5 foods to keep her 'immune system strong' and 'energy high' - CNBC - February 7th, 2025
- Micro Immune Response On-chip (MIRO) models the tumour-stroma interface for immunotherapy testing - Nature.com - February 7th, 2025
- Personalized Therapeutic Vaccine Steers the Immune System to Fight Kidney Cancer | Newswise - Newswise - February 7th, 2025
- Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma - Nature.com - February 7th, 2025
- Serotonin attenuates tumor necrosis factor-induced intestinal inflammation by interacting with human mucosal tissue - Nature.com - February 7th, 2025
- Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquidliquid phase separation-related genes - Nature.com - February 7th, 2025
- FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy - Nature.com - February 7th, 2025
- Young Innovators: U of S researcher uses bat immune systems to find next generation therapies - Saskatoon Star-Phoenix - February 7th, 2025
- World Cancer Day 2025: Chronic stress, immune system, and cancer risk- How are these connected? - The Times of India - February 7th, 2025
- New research unlocks key to long-lasting immune response in cancer and chronic diseases - The Peter Doherty Institute for Infection and Immunity - February 7th, 2025
- Microbial Dynamics and Immune Response to NTHi in COPD - Physician's Weekly - February 7th, 2025
- MHE Week in Review RFK Jr. Spotlight - Managed Healthcare Executive - February 7th, 2025
- Psoriasis Basics: Overview, Symptoms, and Causes - January 27th, 2025
- Vitiligo Symptoms, Treatment & Causes | NIAMS - January 27th, 2025
- The Surprising Connection Between Obesity, Parasites, and Your Immune System - SciTechDaily - January 27th, 2025
- Versatile 69p spice that boosts immune system can go in soups, smoothies and milk - Express - January 27th, 2025
- How the skins secret immune system could lead to needle-free vaccines - Gavi, the Vaccine Alliance - January 27th, 2025
- Fevers link with a key kind of immunity is surprisingly ancient - Science News Magazine - January 27th, 2025
- Immunology - The Scientist - January 27th, 2025
- Opinion: Immune System And Ageing Why We Get More Vulnerable As We Age - ABP Live - January 27th, 2025
- 'Forever chemicals' (PFAS) may weaken immune function in children, leading to more frequent infections - U.S. Right to Know - January 27th, 2025
- Cellular Signals That Wreak Havoc in Sepsis are Revealed - LabRoots - January 27th, 2025
- New Combination Immunotherapy Targets Melanoma and Breast Cancer with Promising Results - Inside Precision Medicine - January 27th, 2025
- New Research in The Journal of Poultry Science: Trained Immunity Offers Novel Poultry Disease Prevention Strategies - PR Newswire - January 27th, 2025
- Scientists uncover how cancer cells hijack T-cells, making it harder for the body to fight back - Medical Xpress - January 27th, 2025
- MiNK Therapeutics Targets Immune Reconstitution to Combat - GlobeNewswire - January 27th, 2025
- Mitochondria may be a promising therapeutic target for inflammatory diseases - Medical Xpress - January 27th, 2025
- Explainer: What is Guillain-Barr Syndrome and how it affects the immune system - Mathrubhumi English - January 27th, 2025
- Yes, Some Vaccines Contain Aluminum. Thats a Good Thing. - The New York Times - January 27th, 2025
- You Are What You Eat? MD Breaks Down The Science Of The Gut Microbiome - mindbodygreen - January 27th, 2025
- Potential gamechanger: Researchers discover basis for immunotherapy-induced myocarditis - Healio - January 27th, 2025
- Ozempic and Wegovy may boost health, from addiction to dementia - BBC.com - January 27th, 2025
- Neutrophil diversity and function in health and disease - Nature.com - December 6th, 2024
- Harnessing the Power of the Immune System for Breast Cancer Treatment - Breast Cancer Research Foundation - December 6th, 2024
- Study Examines Neoantigen Landscapes and Their Role in Immunotherapy Efficacy - Consult QD - December 6th, 2024
- The 5 Best Teas to Support Your Immune System This Cold & Flu Season - EatingWell - December 6th, 2024
- Engineered immune cells may be able to tame inflammation - Medical Xpress - December 6th, 2024
- Hybrid model of tumor growth, angiogenesis and immune response yields strategies to improve antiangiogenic therapy - Nature.com - December 6th, 2024
- Opioids interfere with cancer immunotherapy, but another type of drug could help - Medical Xpress - December 6th, 2024
- RANKL cytokine restores thymus cells in old mice, reducing tumor growth and improving T cell immune response - Fierce Biotech - December 6th, 2024
- Predictive role of neutrophil percentage-to-albumin ratio, neutrophil-to-lymphocyte ratio, and systemic immune-inflammation index for mortality in... - December 6th, 2024
- Immuno-Oncology Strategic Industry Research Report 2023-2024 & 2030: Approval of Pembrolizumab (Keytruda) and Nivolumab (Opdivo), which Target... - December 6th, 2024
- Study cracks the cold case of immunotherapy resistance - News-Medical.Net - December 6th, 2024
- New immune therapy improves survival and reduces tumor burden in glioblastoma - News-Medical.Net - December 6th, 2024
- Identification of immune-related hub genes and potential molecular mechanisms involved in COVID-19 via integrated bioinformatics analysis - Nature.com - December 6th, 2024
- Immune Cell Breakthrough: Scientists Discover a Hidden Ally in the Fight Against Cancer - SciTechDaily - December 6th, 2024
- Rising temperatures impact the immune system of wild monkeys - Earth.com - December 6th, 2024
- Study declaring Alzheimer's to be a "brain disease" proven to be fabricated - Earth.com - December 6th, 2024
- Warming temperatures impact immune performance of wild monkeys, U-M study shows - University of Michigan News - December 6th, 2024
- New study explores heart risks of cancer immunotherapy - News-Medical.Net - December 6th, 2024
- 'Incredible' way to boost your immune system naturally and ward of colds and flu this winter - The Mirror - December 6th, 2024
- Tis the Season to Boost Your Immune System - Mix93.3 - December 6th, 2024
- A mathematical model simulating the adaptive immune response in various vaccines and vaccination strategies - Nature.com - October 14th, 2024
- Fox Chase Cancer Center Researchers Find Gene That Triggers Immune Response in Treatment-Resistant Small-Cell Lung Cancer - Fox Chase Cancer Center - October 14th, 2024
- What Does It Mean to Be Immunocompromised? - The New York Times - October 14th, 2024
- Scientist hopes to cure Type 1 diabetes by disguising stem cells - The University of Arizona - October 14th, 2024
- Watching an infection unfold with a sphingolipid probe - Drug Discovery News - October 14th, 2024
- The cells that protect your brain against infection could also be behind some chronic diseases - BBC.com - October 14th, 2024
- On Nutrition: Foods that help strengthen the immune system - LimaOhio.com - October 14th, 2024
- An integral T cell pathway has implications for understanding sex-based immune response - Medical Xpress - October 14th, 2024
- Immune Response Linked to Lewy Body Formation - Neuroscience News - October 14th, 2024
- Are vaccines the future of cancer prevention? - Genetic Literacy Project - October 14th, 2024
- The Gut Microbiome and Autoimmunity - Inside Precision Medicine - October 14th, 2024
- Researchers discover how oral cancer cells may block the body's immune response - News-Medical.Net - September 21st, 2024
- Are Vaccines More Effective When You Believe in Them? - Greater Good Science Center at UC Berkeley - September 21st, 2024
- Researchers discover immune response to dengue can predict risk of severe reinfections - Medical Xpress - September 21st, 2024
- Texas Researchers Find Acid Walls That Shield Cancer Tumors from Bodys Immune System Response - DARKDaily.com - Laboratory News - September 21st, 2024
- Lysosomes in the immunometabolic reprogramming of immune cells in atherosclerosis - Nature.com - September 21st, 2024
- A new way to reprogram immune cells and direct them toward anti-tumor immunity - MIT News - September 21st, 2024
- Unravelling the many mysteries of the immune system - Cosmos - September 21st, 2024
- Long COVID patients maintain robust immune memory two years after infection - News-Medical.Net - September 21st, 2024
- Nutraceuticals and pharmacological to balance the transitional microbiome to extend immunity during COVID-19 and other viral infections - Journal of... - September 21st, 2024