A new, non-invasive knee procedure could bring some relief for patients suffering from debilitating chronic pain, for whom surgery is not an option.
The treatment, recently approved by the Food and Drug Administration, is called cooled radio frequency ablation and is a less drastic option for people with moderate to severe osteoarthritis pain who are not ready to have knee replacement surgery, or who have health conditions that dont make them a good candidate for surgery.
Marketed as "Coolief", the procedure uses radio frequency to target and mute the nerves responsible for sending pain signals from the arthritic knee to the brain. Coolief doesnt repair arthritis in the knee, but eases the pain, helping patients go back to activities without discomfort and fewer medications.
What we're changing is the wiring of the knee so we're taking away the pain signal and interrupting it," Dr. Amin Sandeep, a pain specialist at Rush University Medical Center in Chicago who performs the procedure, told NBC News.
One 2016 study compared Coolief to popular cortisone injections, with patients reporting greater, longer-lasting pain relief with the new treatment than injections. Coolief reduces pain for about to 6 to 12 months, depending on how fast the nerves in the knee regenerate.
Related: Common Knee Surgery May Not Help You
Osteoarthritis can affect any joint when the cartilage wears off over time, often striking big joints like the knee, causing pain, swelling and stiffness. According to the American Academy of Orthopedic Surgeons, nearly 10 million Americans had osteoarthritis of the knee in 2010.
The three current recommended approaches for knee arthritis pain are physical therapy, non-steroidal anti-inflammatory drugs such as ibuprofen and naproxen, or the opioid painkiller tramadol.
But those didn't help Felicia McCloden, a 65-year-old grandmother from outside of Chicago. The excruciating pain in her right knee made simple tasks like grocery shopping impossible.
I had inflammation, swelling, and my knee was like the size of a golf ball, McCloden told NBC News. "The arthritis was so bad that I could barely step down without severe pain.
Because she wasnt eligible for a knee replacement she tried cortisone injections, physical therapy, medications nothing relieved her pain.
"I thought I was going to limp for the rest of my life," she said.
Related: What Really Helps Knee Pain? The Answer May Surprise You
In May, McCloden underwent the Coolief treatment and the result was instant.
I couldn't even imagine first of all, not having the pain," she said. "It erased all of that.
The outpatient procedure typically takes about 40 minutes, is performed with local anesthesia and doesnt require an incision. Instead, doctors use specialized needles that emit radio frequencywaves into the knee. The cost of the treatment is between $2,000 and $4,000. Because it was just approved by the FDA in April, the treatment is not widely available yet, but pain centers across the country are beginning to offer it.
Some of the reported risks from the procedure include bleeding and infection. "Though patients have a risk of the physician hitting the wrong nerve, that is extremely rare in the hands of an experienced professional, Amin said.
Recovery time is minimal, with most patients walking immediately after the procedure and resuming normal activities in a day or two.
For some patients with structural problems of the knee, the procedure won't help, said pain specialist Dr. Edgar Ross, associate professor of anesthesia at Brigham and Womens Hospital.
"But lets say a patient is younger, instead of going for a total knee replacement early, which might have to be repeated later on, Coolief can postpone the need for the total knee replacement," Ross told NBC News.
Coolief can be repeated if necessary, but it's not a permanent solution. While it reduces pain, it can't stop the progression of osteoarthritis.
"While it can delay total knee replacement, knee replacement may still eventually be necessary in a big number of patients," said Dr. Dennis Cardone, associate professor of orthopedic surgery at NYU Langone Medical Center.
Link:
Cool' New Knee Procedure Eases Arthritis Pain Without Surgery - NBCNews.com
- 001 Treating Adult Artritis with Stem Cells Shows Incredible Promise [Last Updated On: June 30th, 2010] [Originally Added On: June 29th, 2010]
- 002 Platelet Rich Plasma for hair loss with or without Hair Transplant - Video [Last Updated On: November 23rd, 2011] [Originally Added On: November 23rd, 2011]
- 003 Stem cell treatment by Adiva Health Care India after Spinal Cord Injury - Video [Last Updated On: November 23rd, 2011] [Originally Added On: November 23rd, 2011]
- 004 HIV/AIDS: Advancing Stem Cell Therapies: 2011 CIRM Grantee Meeting - Video [Last Updated On: January 15th, 2012] [Originally Added On: January 15th, 2012]
- 005 Skin cells turned into neural precusors, bypassing stem-cell stage [Last Updated On: January 31st, 2012] [Originally Added On: January 31st, 2012]
- 006 VistaGen Therapeutics Enters Strategic Drug Screening Collaboration With Vala Sciences [Last Updated On: March 21st, 2012] [Originally Added On: March 21st, 2012]
- 007 Entest BioMedical Excited With Progress on 10 Dog Pilot Study of "Universal Donor" Stem Cell Treatment for Canine ... [Last Updated On: March 21st, 2012] [Originally Added On: March 21st, 2012]
- 008 Mechanism found connecting metastatic breast cancer and arthritis [Last Updated On: April 2nd, 2012] [Originally Added On: April 2nd, 2012]
- 009 Tulsa Arthritis walk set for Saturday [Last Updated On: May 17th, 2012] [Originally Added On: May 17th, 2012]
- 010 San Rafael dog gets arthritis relief from stem cell treatment [Last Updated On: August 6th, 2012] [Originally Added On: August 6th, 2012]
- 011 TiGenix : completes patient enrollment in Phase IIa rheumatoid arthritis study [Last Updated On: August 8th, 2012] [Originally Added On: August 8th, 2012]
- 012 Stem cells may prevent post-injury arthritis [Last Updated On: August 11th, 2012] [Originally Added On: August 11th, 2012]
- 013 'Humanized' mice advance study of rheumatoid arthritis [Last Updated On: October 4th, 2012] [Originally Added On: October 4th, 2012]
- 014 'Humanized' mice may enable discovery of better medicines for rheumatoid arthritis [Last Updated On: October 5th, 2012] [Originally Added On: October 5th, 2012]
- 015 Innocent Intrigue : Hans S. Keirstead at TEDxOrangeCoast - Video [Last Updated On: November 4th, 2012] [Originally Added On: November 4th, 2012]
- 016 Stem Cells Rheumatoid Arthritis Treatment: A New Discovery... Will It Work? - Video [Last Updated On: November 4th, 2012] [Originally Added On: November 4th, 2012]
- 017 What Areas of Arthritis Do Autologous Stem Cells Work Best For? - Video [Last Updated On: November 15th, 2012] [Originally Added On: November 15th, 2012]
- 018 Adapts to any job: sugar for stem cell arthritis treatment.mp4 - Video [Last Updated On: February 11th, 2013] [Originally Added On: February 11th, 2013]
- 019 Knee arthritis repair... Is it just injecting stem cells into the knee...No! - Video [Last Updated On: February 23rd, 2013] [Originally Added On: February 23rd, 2013]
- 020 BMP needed for cartilage repair and growth in arthritis - Video [Last Updated On: February 24th, 2013] [Originally Added On: February 24th, 2013]
- 021 Alternative to knee replacement: The guinea pig arthritis model! - Video [Last Updated On: April 21st, 2013] [Originally Added On: April 21st, 2013]
- 022 Stem cell arthritis treatment and cartilage repair using Sox... Huh? - Video [Last Updated On: May 10th, 2013] [Originally Added On: May 10th, 2013]
- 023 Blood vessels and stem cells for arthritis treatment - Video [Last Updated On: May 12th, 2013] [Originally Added On: May 12th, 2013]
- 024 Malibu gets stem cell treatment to help his arthritis - Video [Last Updated On: September 24th, 2013] [Originally Added On: September 24th, 2013]
- 025 What are sources of stem cells in the adult ... implications for arthritis treatment - Video [Last Updated On: October 13th, 2013] [Originally Added On: October 13th, 2013]
- 026 Ankle arthritis treatment... what are thre options? - Video [Last Updated On: October 17th, 2013] [Originally Added On: October 17th, 2013]
- 027 Rejection... is it a problem with stem cell arthritis treatment? - Video [Last Updated On: December 16th, 2013] [Originally Added On: December 16th, 2013]
- 028 Shoulder Arthritis: Non-Surgical Alternatives To Help Your Body Heal - Video [Last Updated On: February 1st, 2014] [Originally Added On: February 1st, 2014]
- 029 Arthritis Treatment...Three Dimensional Scaffolds Help Stem Cells Produce Hyaline Cartilage - Video [Last Updated On: February 17th, 2014] [Originally Added On: February 17th, 2014]
- 030 - Rheumatoid Arthritis and Parkinsons: Stem cell treatment - Video [Last Updated On: February 25th, 2014] [Originally Added On: February 25th, 2014]
- 031 Rheumatoid arthritis | umbilical cord stem cells for ra - Video [Last Updated On: June 1st, 2014] [Originally Added On: June 1st, 2014]
- 032 Knee arthritis six months after stem cell injection by Dr Harry Adelson - Video [Last Updated On: June 29th, 2014] [Originally Added On: June 29th, 2014]
- 033 Knee arthritis one year after bone marrow stem cells by Harry Adelson, N.D. - Video [Last Updated On: September 13th, 2014] [Originally Added On: September 13th, 2014]
- 034 Dog's arthritis greatly helped by stem cell treatment - Video [Last Updated On: January 23rd, 2015] [Originally Added On: January 23rd, 2015]
- 035 Arthritis | Treatment for arthritis | www.stemrx.in - Video [Last Updated On: January 31st, 2015] [Originally Added On: January 31st, 2015]
- 036 Blood stem cells, Degenerative arthritis in a dog. - Video [Last Updated On: February 4th, 2015] [Originally Added On: February 4th, 2015]
- 037 Living with Arthritis [Last Updated On: May 19th, 2015] [Originally Added On: May 19th, 2015]
- 038 Rheumatoid arthritis - Wikipedia, the free encyclopedia [Last Updated On: May 19th, 2015] [Originally Added On: May 19th, 2015]
- 039 CDC - Arthritis - Basics - FAQs [Last Updated On: May 19th, 2015] [Originally Added On: May 19th, 2015]
- 040 Psoriatic arthritis - Wikipedia, the free encyclopedia [Last Updated On: May 22nd, 2015] [Originally Added On: May 22nd, 2015]
- 041 Arthritis - Wikipedia, the free encyclopedia [Last Updated On: June 1st, 2015] [Originally Added On: June 1st, 2015]
- 042 CDC - Arthritis - Basics - Definition - Rheumatoid Arthritis [Last Updated On: June 15th, 2015] [Originally Added On: June 15th, 2015]
- 043 Arthritis : Causes, Signs & Diagnosis - Healthline [Last Updated On: June 26th, 2015] [Originally Added On: June 26th, 2015]
- 044 Arthritis: Facts on Diet, Treatment and Symptoms [Last Updated On: July 2nd, 2015] [Originally Added On: July 2nd, 2015]
- 045 CDC - Arthritis - Data and Statistics - Arthritis Related ... [Last Updated On: July 3rd, 2015] [Originally Added On: July 3rd, 2015]
- 046 Home Remedies for Arthritis Pain: Symptoms, Treatment ... [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 047 Rheumatoid Arthritis (RA) [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 048 Knee Arthritis - Diagnosis and Treatment of Wear and Tear [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 049 Natural Cures for Arthritis - Earth Clinic [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 050 Rheumatoid Arthritis Condition Center - Health.com [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 051 What is Arthritis? (with pictures) - wiseGEEK [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 052 Arthritis Information from Drugs.com [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 053 CCFA: Arthritis [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 054 Arthritis | UW Orthopaedics and Sports Medicine, Seattle [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 055 Arthritis Symptoms, Diagnosis, and Treatment [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 056 Arthritis - KidsHealth [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 057 Arthritis, Causes, Tests, Diagnosis & Treatment [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 058 Arthritis Symptoms, Diagnosis, Treatments and Causes ... [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 059 Arthritis - Chronic Arthritis - Arthritis Treatment ... [Last Updated On: July 9th, 2015] [Originally Added On: July 9th, 2015]
- 060 Arthritis: Get the Facts About Symptoms and Diet [Last Updated On: July 24th, 2015] [Originally Added On: July 24th, 2015]
- 061 Arthritis: Causes, Symptoms and Treatments [Last Updated On: July 24th, 2015] [Originally Added On: July 24th, 2015]
- 062 Osteoarthritis - Wikipedia, the free encyclopedia [Last Updated On: August 3rd, 2015] [Originally Added On: August 3rd, 2015]
- 063 Award-Winning Arthritis & Rheumatology Practice | ARAPC [Last Updated On: August 4th, 2015] [Originally Added On: August 4th, 2015]
- 064 CDC - Arthritis - Basics - Definition - Osteoarthritis [Last Updated On: August 14th, 2015] [Originally Added On: August 14th, 2015]
- 065 Arthritis: MedlinePlus Medical Encyclopedia [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- 066 Arthritis | At A Glance Reports | Publications | Chronic ... [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- 067 About Arthritis [Last Updated On: September 2nd, 2015] [Originally Added On: September 2nd, 2015]
- 068 Foods and Arthritis | The Physicians Committee [Last Updated On: September 3rd, 2015] [Originally Added On: September 3rd, 2015]
- 069 Arthritis & Joint Pain - Orthopedics Advice from About.com [Last Updated On: September 3rd, 2015] [Originally Added On: September 3rd, 2015]
- 070 Arthritis - Arthritis Causes - Symptoms, Treatments, and ... [Last Updated On: September 3rd, 2015] [Originally Added On: September 3rd, 2015]
- 071 Rheumatoid Arthritis: Medication, Treatment and Diet Facts [Last Updated On: September 3rd, 2015] [Originally Added On: September 3rd, 2015]
- 072 Arthritis | ASPCA [Last Updated On: September 3rd, 2015] [Originally Added On: September 3rd, 2015]
- 073 arthritis | disease | Britannica.com [Last Updated On: September 3rd, 2015] [Originally Added On: September 3rd, 2015]
- 074 CDC - Arthritis - Physical Activity for Arthritis - Overview [Last Updated On: September 11th, 2015] [Originally Added On: September 11th, 2015]
- 075 Arthritis & Joint Conditions - Rehabilitation Institute of ... [Last Updated On: September 15th, 2015] [Originally Added On: September 15th, 2015]
- 076 Fluoride Action Network | Arthritis [Last Updated On: September 15th, 2015] [Originally Added On: September 15th, 2015]
- 077 Arthritis - UpToDate [Last Updated On: September 15th, 2015] [Originally Added On: September 15th, 2015]
- 078 Arthritis News -- ScienceDaily [Last Updated On: September 18th, 2015] [Originally Added On: September 18th, 2015]
- 079 Arthritis - RadiologyInfo.org [Last Updated On: September 20th, 2015] [Originally Added On: September 20th, 2015]
- 080 Arthritis | Taking Charge of Your Health & Wellbeing [Last Updated On: September 20th, 2015] [Originally Added On: September 20th, 2015]