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Archive for the ‘Regenerative Medicine’ Category

Regenerative Medicine Lecture and Discussion with Students – Video

Thursday, November 15th, 2012


Regenerative Medicine Lecture and Discussion with Students
The first presentation of the fall 2012 Topics in Regenerative Medicine lecture series featured Dr. John Warner who discussed his research on the development of new treatment approaches for life-threatening diseases. Dr. Warner, Scientific Director of Clinical Research/Stem Cell Institute at the University of Minnesota is internationally recognized as an expert in stem cells and umbilical cord blood transplantation.From:SacStateVideoViews:2 0ratingsTime:02:15More inEducation

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Cell Therapy Industry Group Welcomes its 4,000th member

Sunday, November 11th, 2012
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I'm pleased to point out that today the LinkedIn Cell Therapy Industry Group welcomed its 4,000th member today. 


The Cell Therapy Industry group was created to serve as a network of those in the cell therapy industry. The group acts as a vehicle for referrals, networking, information, and facilitating collaboration.  The group's focus is on the activities of companies in and serving the space.


The group began in July 2008. It took 2.5 years to reach the first 1000 members, 9 mos to reach 2,0000, 6 months to reach 3,000, and 6 months to meet today's 4,000 member mark. 


As is typical, there is a very high percentage of passive participants but the group benefits from an avid group of participants who post, share, exchange, and debate on a range of topics ranging from regulatory, clinical, commercial, scientific, manufacturing, financial, and other topics of interest to the group.


As the group has grown I've noted two trends pertaining to the composition of the membership:  (a) having tapped out the c-level suite, growth is increasingly coming from down the hierarchy of the corporate food chain and including those in the operational trenches, and (b) a much higher ratio of new members of late is from outside the US, presumably as LinkedIn increasingly penetrates OUS markets.


We strive hard to maintain the quality of the participation by screening each applicant, deleting off-topic posts, moving promotional posts to the "promotions" tab" and encouraging a balance of news-sharing with useful discussion threads.


I'm proud to say the group has become a vibrant and valuable part of the sector due to the hard work and contributions of all involved.    


As these kind of virtual networks become exponentially larger and provide different value than the professional societies representing the sector, I will be fascinated to watch if and how this affects how sectors like our interact and how this will impact the traditional value proposition of member-based professional societies.


If you are not a member of the LinkedIn Cell Therapy Industry Group, check it out.


--Lee

http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/EOlUEgJGsTQ/cell-therapy-industry-group-welcomes.html

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Cell Therapy Industry Group Welcomes its 4,000th member

Sunday, November 11th, 2012
Tweet 

I'm pleased to point out that today the LinkedIn Cell Therapy Industry Group welcomed its 4,000th member today. 


The Cell Therapy Industry group was created to serve as a network of those in the cell therapy industry. The group acts as a vehicle for referrals, networking, information, and facilitating collaboration.  The group's focus is on the activities of companies in and serving the space.


The group began in July 2008. It took 2.5 years to reach the first 1000 members, 9 mos to reach 2,0000, 6 months to reach 3,000, and 6 months to meet today's 4,000 member mark. 


As is typical, there is a very high percentage of passive participants but the group benefits from an avid group of participants who post, share, exchange, and debate on a range of topics ranging from regulatory, clinical, commercial, scientific, manufacturing, financial, and other topics of interest to the group.


As the group has grown I've noted two trends pertaining to the composition of the membership:  (a) having tapped out the c-level suite, growth is increasingly coming from down the hierarchy of the corporate food chain and including those in the operational trenches, and (b) a much higher ratio of new members of late is from outside the US, presumably as LinkedIn increasingly penetrates OUS markets.


We strive hard to maintain the quality of the participation by screening each applicant, deleting off-topic posts, moving promotional posts to the "promotions" tab" and encouraging a balance of news-sharing with useful discussion threads.


I'm proud to say the group has become a vibrant and valuable part of the sector due to the hard work and contributions of all involved.    


As these kind of virtual networks become exponentially larger and provide different value than the professional societies representing the sector, I will be fascinated to watch if and how this affects how sectors like our interact and how this will impact the traditional value proposition of member-based professional societies.


If you are not a member of the LinkedIn Cell Therapy Industry Group, check it out.


--Lee

http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/EOlUEgJGsTQ/cell-therapy-industry-group-welcomes.html

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CombiCult® Workflow – Video

Friday, November 9th, 2012


CombiCult® Workflow
A overview on how Plasticell (www.plasticell.co.uk) uses combinatorial cell culture (CombiCult®) to discover optimised stem cell differentiation protocols in record time, at a fraction of the cost of the status quo while reducing project return risk. CombiCult® is used by our customers in a range of applications in regenerative medicine, cell therapy and research and development.From:PlasticellLimitedViews:1 0ratingsTime:06:40More inScience Technology

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Integrating History And Philosophy Of Science – Video

Friday, November 9th, 2012


Integrating History And Philosophy Of Science
ll4.me Integrating History And Philosophy Of Science From the contents: Introduction by Seymour Mauskopf and Tad Schmaltz Part I: General Reflections Thomas Kuhn and Interdisciplinary Conversation: Why Historians and Philosophers of Science Stopped Talking to One Another , Jan Golinski The History and Philosophy of Science History, David M. Miller What in Truth Divides Historians and Philosophers of Science?, Kenneth Caneva History and Philosophy of Science: Recollections and Reflections, Ronald Giere Philosophy of Science and Its Historical Reconstructions , Peter Dear The Underdetermination Debate: How Lack of History Leads to Bad Philosophy, Wolfgang Pietsch Part II: Case Studies Beyond Case Studies: History as Philosophy, Hasok Chang Hidden Entities and Experimental Practice: Renewing the Dialogue between History and Philosophy of Science, Theodore Arabatzis Studying Methodological Thought: S. Weir Mitchell s Research on the Venom of Poisonous Snake, Jutta Schickore Quantum Gravity: History, Historiography and Philosophy, Dean Rickles Social Epistemology of Stem Cell Research: History, Philosophy and Experiment, Melinda Fagan History and Philosophy of Science at Work: Making Regenerative Medicine Better EAN/ISBN : 9789400717459 Publisher(s): Springer, Berlin, Springer Netherlands Discussed keywords: Geschichtsschreibung, Interdisziplinaritt, Wissenschaftsphilosophie Format: ePub/PDF Author(s): Mauskopf, Seymour - Schmaltz, Tad From the contents: Introduction by ...From:susanbranch9865Views:0 0ratingsTime:00:16More inPeople Blogs

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stem cell banking | Knowing More About Cord Blood Banking – Video

Friday, November 9th, 2012


stem cell banking | Knowing More About Cord Blood Banking
http://www.cordbloodrecommendation.com The umbilical cord blood is rich in stem cells as the baby #39;s organs, tissues and body is developed by it. Diseases that are genetically based would most likely be an allogenic transplant. Human umbilical cord blood cells are very rich in stem cells and progenitor cells which make them the perfect place to take cells from and then store them in a cord blood bank or a stem cells bank. There is also another option given by non-profit cord blood banks, of free programs through which one can store umbilical cord blood stem cell samples. A man can change his god-gifted features wishfully with the help of science. Given the progress that stem cell research and regenerative medicine have attained at present, and the promise that they show for the future, stem cell transplants may one day provide a cure for type 1 diabetes, heart disease, and brain injury, among other potentially life threatening and debilitating illnesses and conditions with inadequate treatment options today. One study in particular by Wagner, et al. ""The theory exists that any reduction in the volume of umbilical cord blood units in albumin or dextran prior to transfusing into patients leads to better cell viability. The mother will be informed about the status of the blood unit and the test results so that she is aware of any infection or disease that might affect her baby. Many parents see placental and cord blood banking as valuable tools to help them secure potentially ...From:fivespanishViews:0 0ratingsTime:01:18More inScience Technology

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Fat-derived Stem Cells Hold Potential for Regenerative Medicine

Friday, November 9th, 2012

PHILADELPHIA As researchers work on reconfiguring cells to take on new regenerative properties, a new review from Penn Medicine plastic surgeons sheds additional light on the potential power of adipose-derived stem cells - or adult stem cells harvested from fatty tissue - in reconstructive and regenerative medicine.

Reconstructive plastic surgeons have clinically integrated "fat grafting" into different surgeries for years, for breast, facial, and other reconstructive and restorative surgeries, with good success. Now, researchers are beginning to understand the power that fatty tissue holds. This new paper, published in the Aesthetic Surgery Journal, enforces that adipose-derived stem cells can be routinely isolated from patients and, once molecular methods are worked out, may be useful for a multitude of regenerative medicine applications.

"The opportunities for regenerative medicine interventions based on adult stem cells are tremendous. It is critically important for us to better understand the biology of these cells so that we can develop novel, safe and effective treatments for our patients using their own cells." said the paper's senior author, Ivona Percec, MD, PhD, assistant professor in the division of Plastic Surgery in the Perelman School of Medicine at the University of Pennsylvania.

Many groups are looking into different modes of isolating and modifying these cells for their regenerative properties, including experts at Penn's Institute for Regenerative Medicine and around Penn Medicine. For example, Dr. Percec's team is conducting translational research into the mechanisms controlling adipose-derived stem cells, and how they contribute to the normal human aging process.

Stem cells can undergo multiple divisions without differentiation, making them useful tools for cell-replacement therapy. Embryonic stem cells can convert to any cell type, whereas adult stem cells, like the stem cells derived from fat, can differentiate into many, but not all, cell types. A person's own fat tissue could then potentially be converted into cells specially designed to repair damage to the heart, cartilage, blood vessels, brain, muscle, or bone.

As regenerative medicine techniques are refined, experts will continue to explore the utility and benefits of stem cells derived from adipose tissue.

The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.

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Fat-derived Stem Cells Hold Potential for Regenerative Medicine

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cryocell | Why Store Your Cord Blood In a Bank? – Video

Friday, November 9th, 2012


cryocell | Why Store Your Cord Blood In a Bank?
http://www.cordbloodrecommendation.com A large number of people die waiting for a transplant due to this reason. Before any blood donations are made it is important for a pregnant mother interested to make the donation to contact the bank before the thirty fourth week of her pregnancy. However, private banking is generally not recommended unless there is a family history of specific genetic diseases. It contains stem cells that have been found to be excellent for research and treatment of many diseases. A man can change his god-gifted features wishfully with the help of science. Given the progress that stem cell research and regenerative medicine have attained at present, and the promise that they show for the future, stem cell transplants may one day provide a cure for type 1 diabetes, heart disease, and brain injury, among other potentially life threatening and debilitating illnesses and conditions with inadequate treatment options today. One study in particular by Wagner, et al. ""Settling on a name for your newborn is definitely something all parents spend time doing, but one decision that is rarely thought of or overlooked is saving your newborn #39;s cord blood. The mother will be informed about the status of the blood unit and the test results so that she is aware of any infection or disease that might affect her baby. Many parents see placental and cord blood banking as valuable tools to help them secure potentially lifesaving treatment options their families may some day ...From:loshoteles enmedellinViews:0 0ratingsTime:01:18More inScience Technology

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454: A Documentary About Stem Cell Research – Video

Tuesday, November 6th, 2012


454: A Documentary About Stem Cell Research
In 2004 Alex Goldberg, then a 20 year old local filmmaker began a documentary on stem cell research at the University of Washington. On June 16 2011, he died before the film was finished. This film highlights the need for this research to continue in order to save thousands of lives. In this unsettling political climate, the film resonates. It was made during the Bush era when stem cell lines were limited, thus stunting the research and in turn a cure for so many diseases. Many thanks to Dr Charles Murry and his staff for their tireless efforts to create therapies in regenerative medicine. Dr Murry may be reached through the University of Washington research labs. If you would like to make donations to help fund this research and the researchers who work without appropriate compensation please click the following link: depts.washington.eduFrom:Leta GoldbergViews:67 2ratingsTime:15:03More inEducation

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umbilical cord stem cells | Cord Blood Storage and Why – Video

Tuesday, November 6th, 2012


umbilical cord stem cells | Cord Blood Storage and Why
http://www.cordbloodrecommendation.com By preserving this cord blood through cord blood banking, your baby will be ensured a perfect source of cells in the event of some unfortunate accident, disease or other life threatening illness. Safety is a concern in the public banks because of the high cost of maintaining the storage unit. Besides this, children without siblings and people belonging to certain races or ethnicities, who don #39;t have access to other people of their race in their area, also face problems. Sources of stem cells, such as blood, fats, bone, or umbilical cords were simply named as sources, not as natural resources. By preserving your baby #39;s cord blood, you are actually saving your child from the dangers of waiting for matching donors during emergencies. ""Regenerative medicine is the next evolution of medical treatments. Stromal cells are a kind of cells that form bone, cartilage, fat, and fibrous connective tissue. There are people who are against this practice as well and there are many opinions supporting it too therefore it is best to consult your doctor regarding this issue and get the right advice. For this, the patient needs a donor whose tissues and cells match his own. In case the cord blood is collected before the removal of placenta, the umbilical cord is clamped and detached as usual. - Stem groups can be certainly obtained from cord blood- flex blood stem groups are a 100% reach for the patron, 50% reach for biological parents and 25% reach for blood ...From:Alexander santafeViews:0 0ratingsTime:01:13More inScience Technology

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Texas Can Become Center for Regenerative Medicine

Tuesday, November 6th, 2012

Gov. Rick Perry today highlighted Texas leading role in the advancement of regenerative medicine to produce safe, effective and ethical adult stem cell therapies. The governor spoke at the inaugural Houston Stem Cell Summit, which focuses on adult stem cell research and its potential to tackle life-threatening diseases.

Im proud Texas is playing a key role in the advancement of adult stem cell research and therapies, both of which are promising for patients and our economy, Gov. Perry said. This conference represents another step in the growth of this industry that I hope and expect will be centered right here in the Lone Star State.

Texas has taken clear steps to advance research in ethical regenerative medicine as quickly and safely as possible, while protecting patients receiving these treatments in the state. Earlier this year, the Texas Legislature, Texas Medical Board and Texas Department of Health and Human Services set up a regulatory framework to guide companies, institutions and physicians collaborating to produce effective stem cell research.

Additionally, Texas continues to attract top researchers in biotechnology and regenerative medicine thanks to our commitment to investing in the technologies of the future through the Cancer Prevention Research Institute of Texas (CPRIT) and Texas Emerging Technology Fund (TETF). CPRIT has funded 427 awards totaling more than $756 million for cancer research, commercialization and prevention in academic institutions, non-profit organizations and private companies. The TETF has invested more than $180 million in grant-matching and research superiority funds in Texas universities, and more than $194 million in 137 early-stage companies, with more than $103 million of that going directly to biotechnology and life science companies.

Texas researchers have also received more than $52 million in National Institute of Health (NIH) funding in 2009 for adult stem cell studies. These grants have resulted in the Austin Heart Hospital successfully treating heart attack patients with adult stem cells, and success in treating spinal cord injuries and a variety of heart conditions.

The Houston Stem Cell Summit highlights the latest research and breakthroughs regarding the use of adult stem and progenitor cell therapies. The summit covers all aspects of emerging stem cell therapies including the latest in peer reviewed academic stem cell research, breakthroughs in adult stem cell therapies, patient experiences, the business of stem cell therapies and the evolving regulatory environment for stem cell therapies. For more information, please visit http://www.stemcellsummit.com/houston/. To view the governors full remarks, please visit http://governor.state.tx.us/news/speech/17803/

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Texas Can Become Center for Regenerative Medicine

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Midwest regenerative medicine symposium to be held in Cincinnati

Tuesday, November 6th, 2012

Public release date: 5-Nov-2012 [ | E-mail | Share ]

Contact: Katie Pence katie.pence@uc.edu 513-558-4561 University of Cincinnati Academic Health Center

CINCINNATIHoxworth Blood Center, the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center will host the Midwest Symposium on New Concepts For Tissue-Specific Regenerative Medicine, Nov 17-18, 2012, in Rieveschl Auditorium of the Vontz Center for Molecular Studies.

The symposium, also being co-sponsored and co-funded by UC's Center for Clinical and Translational Science and Training (CCTST), will focus on research and collaboration regarding regenerative medicinethe process of regenerating human cells, tissues or organs to restore or establish normal function.

The field holds the promise of repairing damaged tissues and organs in the body by stimulating the body's own repair mechanisms or by growing replacement tissues in labs.

Jose Cancelas, MD, PhD, professor of pediatrics at the UC College of Medicine and director of the research division at Hoxworth Blood Center, is a co-organizer of the symposium and says regenerative medicine expertise is very strong in the region.

"The purpose of the symposium will be to create a forum where investigators and their groups can meet and share ideas and data," he says. "In addition, it will serve as an excellent platform for regional scientific interactions for investigators, postdocs and students that have interest in regenerative medicine and stem cell biology. Hopefully, this meeting will spark collaborations locally and regionally."

Specifically, the meeting will focus on research using stem cells in the body, or those manipulated in a petri dish, to study disease, generate therapeutic tissues and create genetic therapies.

Keynote speakers will deliver addresses followed by short oral presentations with extended discussions to allow interaction among attendees.

"Research presentations will span from how scientists are looking at the use of stem cells to assist with gastrointestinal, pancreas, lung, corneal, skeletal muscle, vascular and cardiac regeneration to genetic therapies and how this research could and is translating to treatment," Cancelas says. "There's a wealth of scientific and clinical stem cell work being done right here in Cincinnati.

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New iPS goal: brains, lungs, kidneys

Sunday, November 4th, 2012

Sunday, Nov. 4, 2012

A science ministry working group studying stem cells and regenerative medicine has updated its road map on induced pluripotent stem-cell research, aiming to create human organs including brains, lungs and kidneys via iPS cells within 10 years.

The group's updated plan, first compiled in 2009, calls for the distribution of iPS cells for regenerative medicine to start within the next two to three years. The announcement comes after Kyoto University professor Shinya Yamanaka jointly won this year's Nobel Prize in physiology or medicine for his revolutionary work in developing iPS cells.

The new road map includes a plan by the government-backed Riken research institute to begin a clinical study in fiscal 2013 on the transplantation of retinas created through iPS cells into patients suffering age-related deterioration in their vision.

In addition, a clinical study on heart muscle will start within three to five years, targeting patients who have suffered heart attacks or are experiencing other cardiac diseases. A study on brain nerve cells will also be launched in five to seven years, mainly for patients afflicted with Parkinson's disease.

Riken official Shinichi Nishikawa, also a member of the ministry's working group, said researchers from various fields should cooperate in compiling safety standards on the use of iPS cells.

The science ministry has sought 8.7 billion for research related to regenerative medicine as part of its budget request for fiscal 2013.

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New iPS goal: brains, lungs, kidneys

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GEN’s "Cellular Therapy Wave Finally Cresting". An overview and data set.

Sunday, November 4th, 2012
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We first provided a listing (with very few details) of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials on this blog late last year (see the posting here).

We are now pleased to we have worked with Genetic Engineering and Biotechnology News and Enal Razvi of Select Biosciences to provide an updated (as of June 2012) and more detailed listing of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials (excluding cell-based immunotherapies which we intend to cover in a follow-up article).

A link to the listing can be found in an article published today entitled "Cellular Therapy Wave Finally Cresting" found in the November 1, 2012 issue of GEN.  

While not my favorite title, the article is a brief - but we hope useful - overview of the sector and its pipeline.  It also provides a snapshot of the cell therapy products already in commercial distribution. 
Some will quibble about the numbers. Certainly others have published larger revenue numbers, for instance, but in our view these have almost always included revenue from cord blood banking which we have excluded.
We encourage you to read the article but for convenience here is a direct link to the spreadsheet.  Of course it's already out-dated but we'll do an update again soon here on this blog.


Hope this is useful.
--Lee


http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/ctijFXeY01M/gens-cellular-therapy-wave-finally.html

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GEN’s “Cellular Therapy Wave Finally Cresting”. An overview and data set.

Sunday, November 4th, 2012
Tweet 

We first provided a listing (with very few details) of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials on this blog late last year (see the posting here).

We are now pleased to we have worked with Genetic Engineering and Biotechnology News and Enal Razvi of Select Biosciences to provide an updated (as of June 2012) and more detailed listing of industry-sponsored late-stage (pivotal, phase 3 and 2/3) cell therapy clinical trials (excluding cell-based immunotherapies which we intend to cover in a follow-up article).

A link to the listing can be found in an article published today entitled "Cellular Therapy Wave Finally Cresting" found in the November 1, 2012 issue of GEN.  

While not my favorite title, the article is a brief - but we hope useful - overview of the sector and its pipeline.  It also provides a snapshot of the cell therapy products already in commercial distribution. 
Some will quibble about the numbers. Certainly others have published larger revenue numbers, for instance, but in our view these have almost always included revenue from cord blood banking which we have excluded.
We encourage you to read the article but for convenience here is a direct link to the spreadsheet.  Of course it's already out-dated but we'll do an update again soon here on this blog.


Hope this is useful.
--Lee


http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/ctijFXeY01M/gens-cellular-therapy-wave-finally.html

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Stem Cell Meeting on the Mesa – Video

Saturday, November 3rd, 2012


Stem Cell Meeting on the Mesa
The 2012 Stem Cell Meeting on the Mesa is a three-day conference aimed at bringing together senior members of the business development and scientific research communities in regenerative medicine to advance stem cell science into cures for debilitating diseases and injuries. The meeting features a nationally recognized Scientific Symposium attended by more than 600 leading scientists and researchers along side the regenerative medicine industry #39;s premier annual Investor and Partnering Forum designed to facilitate a bridge between academia and industry through one-on-one meetings and further the translation of clinical research. Scientific Meeting Agenda at a Glance 8:00 am -- Welcome Remarks Alan Trounson, President, California Institute for Regenerative Medicine 8:15 am -- Morning Keynote Speaker ** NO FILMING - Speaker did not consent to being recorded. Michele De Luca, Professor, Director, Centre for Regnerative Medicine, University of Modena and Reggio Emilia; Scientific Director, Holostem Terapie Avanzate Srl 8:45 am -- Panel 1: Cancer and Cancer Stem Cells Chair: Robert Wechsler-Reya, Professor, Director, Tumor Development Program, Sanford-Burnham Medical Research Institute Panelists: Jeremy Rich, Chairman, Department of Stem Cell Biology and Regenerative Medicine, The Cleveland Clinic Luke Lairson, Assistant Professor, The Scripps Research Institute Ben Spike, Senior Research Associate, Salk Institute for Biological Studies Catriona Jamieson, Associate Professor ...From:SalkInstituteViews:96 0ratingsTime:00:00More inScience Technology

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BioTime Subsidiary OrthoCyte Corporation Announces the Appointment of Francois Binette as Vice President

Saturday, November 3rd, 2012

ALAMEDA, Calif.--(BUSINESS WIRE)--

BioTime, Inc. (NYSE MKT: BTX) and its subsidiary OrthoCyte Corporation today announced the appointment of Francois Binette, PhD, as OrthoCytes Vice President of Research and Business Development. Dr. Binettes primary focus will be to develop and partner near- and long-term product opportunities in regenerative medicine with an emphasis on orthopedic diseases and injuries. OrthoCyte is a wholly owned subsidiary of BioTime, Inc. that develops cellular therapeutics for orthopedic repair, diseases, and injuries.

I am impressed by the robust nature of the novel and diverse progenitors of skeletal tissues that BioTime has isolated using its ACTCellerateTM technology, said Dr. Binette. The ability to generate scalable and precisely identified types of cartilage, bone, and tendon, combined with the HyStem technology for tissue engineering, gives us a remarkable platform for manufacturing an array of novel products to address some of the largest and fastest growing needs in the orthopedic space. I look forward to building on the science and technology developed at OrthoCyte to aggressively develop the companys product pipeline and pursue partnering opportunities.

Francois brings tremendous expertise in regenerative medicine, cell therapy, biologics, biomaterials, and combination medical devices. He also has significant business experience in partnering and collaboration with both start-up and large life science companies, said Michael D. West, PhD, BioTimes Chief Executive Officer. We welcome Francois to the OrthoCyte team and look forward to working together with him in developing commercial product opportunities for the orthopedic repair market.

Dr. Binette most recently was the founder of Rediens Inc., a Bay Area start-up company focused on chronic back pain therapies. Prior to establishing Rediens, he wasDirector of BiologicsR&D for the Spinal & Biologics business unit of Medtronic, Inc., and he also served in a variety of positions with Johnson & Johnson, where he focused on regenerative medicine therapies for various orthopedic indications, including cartilage injuries and back pain. Dr. Binette began his corporate career at Genzyme Tissue Repair, where he helped pioneer Carticel, the first FDA Biologic License Application-approved cell therapy product. Dr. Binette received his PhD in Biochemistry at Laval University in Qubec and was a postdoctoral research fellow at the LaJolla Cancer Research Foundation of the Sanford-Burnham Medical Research Institute and at MGH/Harvard Medical School. He is currently a fellow with the International Cartilage Repair Society.

About OrthoCyte Corporation

OrthoCyte Corporation (OrthoCyte), http://www.orthocyte.com, a subsidiary of BioTime, Inc., is a biotechnology company developing cell-based therapies for orthopedic disease. The company's lead product is OTX-CP07, monoclonal human embryonic progenitor cell lines for the repair of osteoarthritis. In addition, OrthoCyte has proprietary human embryonic stem cell-derived progenitors to skeletal muscle, tendon, and bone, all of which are in the preclinical phase of development.

About BioTime, Inc.

BioTime, headquartered in Alameda, California, is a biotechnology company focused on regenerative medicine and blood plasma volume expanders. Its broad platform of stem cell technologies is enhanced through subsidiaries focused on specific fields of application. BioTime develops and markets research products in the fields of stem cells and regenerative medicine, including a wide array of proprietary ACTCellerate cell lines, HyStem hydrogels, culture media, and differentiation kits. BioTime is developing Renevia (formerly known as HyStem-Rx), a biocompatible, implantable hyaluronan and collagen-based matrix for cell delivery in human clinical applications. BioTime's therapeutic product development strategy is pursued through subsidiaries that focus on specific organ systems and related diseases for which there is a high unmet medical need. BioTime's majority-owned subsidiary Cell Cure Neurosciences Ltd. is developing therapeutic products derived from stem cells for the treatment of retinal and neural degenerative diseases. BioTime's subsidiary OrthoCyte Corporation is developing therapeutic applications of stem cells to treat orthopedic diseases and injuries. Another subsidiary, OncoCyte Corporation, focuses on the diagnostic and therapeutic applications of stem cell technology in cancer, including the diagnostic product PanC-Dx currently being developed for the detection of cancer in blood samples. ReCyte Therapeutics, Inc. is developing applications of BioTime's proprietary induced pluripotent stem cell technology to reverse the developmental aging of human cells to treat cardiovascular and blood cell diseases. BioTime's subsidiary LifeMap Sciences, Inc. markets GeneCards, the leading human gene database, and is developing an integrated database suite to complement GeneCards that will also include the LifeMap database of embryonic development, stem cell research and regenerative medicine, and MalaCards, the human disease database. LifeMap will also market BioTime research products. BioTime's lead product, Hextend, is a blood plasma volume expander manufactured and distributed in the U.S. by Hospira, Inc. and in South Korea by CJ CheilJedang Corporation under exclusive licensing agreements. Additional information about BioTime can be found on the web at http://www.biotimeinc.com.

Forward-Looking Statements

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BioTime Subsidiary OrthoCyte Corporation Announces the Appointment of Francois Binette as Vice President

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The Vatican's Pontifical Council for Culture, NeoStem, The Stem for Life Foundation & STOQ International Announce 'The …

Saturday, November 3rd, 2012

NEW YORK, Nov. 1, 2012 (GLOBE NEWSWIRE) -- The Stem for Life Foundation, NeoStem, Inc. (NYSE MKT:NBS), The Pontifical Council for Culture, and STOQ International today announced that they will host The Second International Vatican Adult Stem Cell Conference: Regenerative Medicine -- A Fundamental Shift in Science & Culture, from within The Vatican, April 11-13, 2013.

This event is part of a five-year collaboration between The Stem for Life Foundation, a not-for-profit organization devoted to raising global awareness of the therapeutic potential of adult stem cells, NeoStem, an emerging leader in the fast growing cell therapy industry, The Vatican's Pontifical Council for Culture and its foundation, called STOQ International (Science, Theology and the Ontological Quest).

With renowned journalists serving as moderators -- Meredith Vieira from NBC News, Bill Hemmer from The Fox News Channel, Peggy Noonan of The Wall Street Journal and Dr. Max Gomez from WCBS-TV -- The Second International Vatican Adult Stem Cell Conference will feature leading adult stem cell scientists and clinicians, thought leaders of faith, ethics and culture, business leaders as well as Ministers of Health, Ambassadors to The Holy See and regulatory officials from around the world. During the event, adult stem cell scientists and clinicians will present an array of medical advancements and ongoing research occurring throughout the world, including the ability to grow replacements for damaged and diseased organs; restoring heart function after heart attack; growing new skin for burn victims; rebalancing our own immune systems, pushing back a rising tide of chronic disease; advancements in cancer therapy; preventing organ rejection and addressing a range of other conditions and trauma, such as MS, traumatic brain injuries and cardiovascular disease via adult stem cell therapies. Throughout the event, patients will share their own stories of the unique, powerful treatments that have helped address their disease and reduce suffering.

"Regenerative medicine is poised to revolutionize disease management by finding new ways to boost the body's ability to heal itself. Whereas today treatment for many diseases is a matter of managing symptoms, regenerative medicine seeks to reverse the course of the disease by targeting its cause and repairing diseased or defective tissues or organs," said Dr. Robin Smith, President of The Stem for Life Foundation. "Not only will our conference educate people of all ages, religions and cultures on the potential of adult stem cells to treat chronic disease as part of this next great frontier, but we will generate a truly international dialogue on regenerative medicine, one that explores the interconnections between scientific breakthroughs, faith, culture and ethics."

The goals of the 2013 Second International Vatican Adult Stem Cell Conference are to:

"The developments within regenerative medicine are of great interest," said Msgr. Tomasz Trafny. "They show how science changes, causing paradigm shifts through interdisciplinary research. Cellular biology is a good example of such changes. These dynamics also cause deep cultural transformations on different levels, from health care to economy, from new technologies to legal issues. Thus, topics that apparently seem to be circumscribed only to strictly scientific discussions or theoretical ones, in fact modify our understanding of social dynamics, relationships and, in the ultimate analysis, our understanding of the human being. Today we acknowledge that insights from natural sciences play a crucial role in our society, having consequences for anthropology, philosophy and even theology. It is our mission and our duty to explore the above dynamics, to offer the best tools for pastoral care, and to encourage understanding of changing culture."

In June, The Pontifical Council for Culture and The Stem for Life Foundation presented the first copy of their forthcoming book, The Healing Cell: How The Greatest Revolution in Medical History is Changing Your Life, to The Holy Father, Pope Benedict XVI. The book is the result of a unique collaboration between the two organizations, and will be available in 2013. It includes a special address by His Holiness Benedict XVI, urging increased support and awareness for advancements in adult stem cell research in order to alleviate human suffering. To reserve a copy of the book, go to:http://www.stemforlife.org/healingcell

To learn more about The Second International Vatican Adult Stem Cell Conference please visit http://www.adultstemcellconference.org.

About The Pontifical Council for Culture

The Pontifical Council for Culture is that Dicastery of the Roman Curia which assists the Pope in the exercise of his supreme pastoral office for the benefit and service of the universal Church and of particular Churches concerning the encounter between the saving message of the Gospel and cultures, in the study of the weighty phenomena of the rift between the Gospel and cultures; indifference in matters of religion; unbelief. It is also concerned with relationships between the Church and the Holy See and the world of culture; in particular it promotes dialogue with contemporary cultures, so that human civilization may become increasingly open to the Gospel, and so that men and women of science, letters and the arts may know that the Church acknowledges their work as a service to truth, goodness and beauty. http://www.cultura.va

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The Vatican's Pontifical Council for Culture, NeoStem, The Stem for Life Foundation & STOQ International Announce 'The ...

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