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Archive for the ‘Regenerative Medicine’ Category

The Science of Mesenchymal Stem Cells and Regenerative Medicine – Arnold Caplan PhD (Part 1) – Video

Saturday, June 8th, 2013


The Science of Mesenchymal Stem Cells and Regenerative Medicine - Arnold Caplan PhD (Part 1)
Professor Arnold Caplan of Case Western Reserve University is widely regarded as "The Father of the Mesenchymal Stem Cell". This lecture is a "must see" for ...

By: http://www.cellmedicine.com

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The Science of Mesenchymal Stem Cells and Regenerative Medicine - Arnold Caplan PhD (Part 1) - Video

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Commercialization of Regenerative Medicine: Learning from Spin-Outs

Sunday, April 28th, 2013
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The meeting “Commercialization of Your Regenerative Medicine Research: Lessons from Spin Out Successes” was hosted by the Oxbridge Biotech Roundtable (OBR) (Oxford, UK) at the University of Oxford in February, 2013, and attracted a multi-stakeholder audience spanning academia and industry. 


The event featured case studies from Gregg Sando, CEO, Cell Medica (London, UK), John Sinden, CSO, Reneuron (Guilford, UK), and Paul Kemp, CEO and CSO, Intercytex (Manchester, UK). 


OBR is a student-led initiative with over 7000 members across eight different UK and US locations with a mission to foster a conversation about the healthcare and life sciences industry. 


Anna French and David A. Brindley, along with some of my assistance, captured and have now published the main themes of the meeting and the major questions facing the regenerative medicine industry and its rapidly emerging subsets of cellular and gene therapies. 


Notably, we discuss the compatibility of regenerative therapies to the existing healthcare infrastructure, biomanufacturing challenges (including scalability and comparability), and the amenability of regenerative therapies to existing reimbursement and investment models. Furthermore, we reiterate key words of advice from seasoned industry leaders intended to accelerate the translation path from lab bench to the marketplace.


To read the review see: Commercialization of Regenerative Medicine: Learning from Spin-Outs


Anna French, R. Lee Buckler, and David A. Brindley. Rejuvenation Research. April 2013, 16(2): 164-170. doi:10.1089/rej.2013.1423.
http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

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http://feedproxy.google.com/~r/CellTherapyBlog/~3/4Uv2o54_hWQ/commercialization-of-regenerative.html

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Commercialization of Regenerative Medicine: Learning from Spin-Outs

Sunday, April 28th, 2013
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The meeting “Commercialization of Your Regenerative Medicine Research: Lessons from Spin Out Successes” was hosted by the Oxbridge Biotech Roundtable (OBR) (Oxford, UK) at the University of Oxford in February, 2013, and attracted a multi-stakeholder audience spanning academia and industry. 


The event featured case studies from Gregg Sando, CEO, Cell Medica (London, UK), John Sinden, CSO, Reneuron (Guilford, UK), and Paul Kemp, CEO and CSO, Intercytex (Manchester, UK). 


OBR is a student-led initiative with over 7000 members across eight different UK and US locations with a mission to foster a conversation about the healthcare and life sciences industry. 


Anna French and David A. Brindley, along with some of my assistance, captured and have now published the main themes of the meeting and the major questions facing the regenerative medicine industry and its rapidly emerging subsets of cellular and gene therapies. 


Notably, we discuss the compatibility of regenerative therapies to the existing healthcare infrastructure, biomanufacturing challenges (including scalability and comparability), and the amenability of regenerative therapies to existing reimbursement and investment models. Furthermore, we reiterate key words of advice from seasoned industry leaders intended to accelerate the translation path from lab bench to the marketplace.


To read the review see: Commercialization of Regenerative Medicine: Learning from Spin-Outs


Anna French, R. Lee Buckler, and David A. Brindley. Rejuvenation Research. April 2013, 16(2): 164-170. doi:10.1089/rej.2013.1423.
http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

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http://feedproxy.google.com/~r/CellTherapyBlog/~3/4Uv2o54_hWQ/commercialization-of-regenerative.html

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A KEY TO REGENERATIVE MEDICINE: Discovery of a new adult stem cell with special properties – Video

Thursday, April 25th, 2013


A KEY TO REGENERATIVE MEDICINE: Discovery of a new adult stem cell with special properties
Learn about the exciting discovery that could revolutionize regenerative medicine by providing a source to produce organs derived from a patient #39;s own stem c...

By: YourekaScience

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A KEY TO REGENERATIVE MEDICINE: Discovery of a new adult stem cell with special properties - Video

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2013 Annual Regenerative Medicine Industry Report

Sunday, April 21st, 2013

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The Alliance for Regenerative Medicine announced today the release of the 2013 annual regenerative medicine industry report.  Here is the announcement in the Wall Street Journal online.

I'm proud to have been a part of putting it together and hope people find it useful.  It is available for download on the ARM website here.  


In addition to the complete download, ARM will make many of the figures, charts,  tables and sections available for members to download and use in their own publications and presentations. Watch for these resources to be announced soon.


























http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

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http://feedproxy.google.com/~r/CellTherapyBlog/~3/yFBYKblnudk/2013-annual-regenerative-medicine.html

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2013 Annual Regenerative Medicine Industry Report

Sunday, April 21st, 2013

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The Alliance for Regenerative Medicine announced today the release of the 2013 annual regenerative medicine industry report.  Here is the announcement in the Wall Street Journal online.

I'm proud to have been a part of putting it together and hope people find it useful.  It is available for download on the ARM website here.  


In addition to the complete download, ARM will make many of the figures, charts,  tables and sections available for members to download and use in their own publications and presentations. Watch for these resources to be announced soon.


























http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/yFBYKblnudk/2013-annual-regenerative-medicine.html

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Chicago Arthritis – What is Regenerative Medicine – Video

Friday, April 12th, 2013


Chicago Arthritis - What is Regenerative Medicine
Dr Tambar at Chicago Arthritis discusses regenerative medicine techniques, prp and stem cells, for arthritis and tendinitis.

By: ChicagoArthritis

Link:
Chicago Arthritis - What is Regenerative Medicine - Video

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New Study at the Center for Regenerative Medicine – Mayo Clinic – Video

Wednesday, February 20th, 2013


New Study at the Center for Regenerative Medicine - Mayo Clinic
The Center for Regenerative Medicine at Mayo Clinic investigates what advances of stem cell biology would be useful to apply in the treatment of patients with end stage diseases. Jorge Rakela, MD, associate director for the Center, provides an overview of the Center which is also involved in a tissue engineering program with Arizona State University. Jeffery Cornella, MD, a gynecological surgeon at Mayo Clinic, and Johnny Yi, MD, a surgical fellow at Mayo Clinic, talk about a study underway to develop new tissue to aid in the treatment of vaginal prolapse and other conditions.

By: mayoclinic

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New Study at the Center for Regenerative Medicine - Mayo Clinic - Video

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Introduction to the Stanford Institute for Stem Cell Biology and Regenerative Medicine – Video

Thursday, February 14th, 2013


Introduction to the Stanford Institute for Stem Cell Biology and Regenerative Medicine
Institute stem cell researchers Michael Longaker, Ravi Majeti, Renee Reijo Pera, Michael Clarke and Maximilian Diehn talk about research on regenerative medicine, cancer therapies and reproduction, and how clinical experiences motivate them to work even harder to find new therapies for disease.

By: institutesofmedicine

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Introduction to the Stanford Institute for Stem Cell Biology and Regenerative Medicine - Video

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Julia Greenstein Regenerative Medicine and Stem Cell Biology – Video

Wednesday, February 13th, 2013


Julia Greenstein Regenerative Medicine and Stem Cell Biology
This clip is part of the Career Girls ongoing series of career guidance/inspiration videos. See more at http://www.careergirls.org

By: careergirls

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Julia Greenstein Regenerative Medicine and Stem Cell Biology - Video

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How to understand stem cells – regenerative medicine – Video

Saturday, January 26th, 2013


How to understand stem cells - regenerative medicine
http://www.12hourmba.com 12 Hour MBA in Stem Cells The 12 Hour MBA in Stem Cells is an introductory level course designed to bridge gaps in your knowledge. It is most useful to new entrants, senior managers needing a big picture refresher, professional advisors and suppliers to the industry. We make it all easy -- leading you through the dynamics of stem cells, the main business drivers, giving you precious insight into where the money is made, stem cell development, commercialisation and ethics. In less than 12 hours you #39;ll: - Understand stem cells from bench to bedside - Discover where the money is made with stem cells - Understand risk and project management techniques for stem cells - Explore practices for stem cell product commercialisation - Learn about regulations, the government and the impact they can have - Consider the ethics of stem cells - Discover what the future holds for stem cells For more information, contact us at: http://www.terrapinntraining.com/contact-us.aspx

By: TerrapinnTraining

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How to understand stem cells - regenerative medicine - Video

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OTT: Breakfast Club Winter 2012 – Human Stem Cells 3.0: The Holy Grail of Regenerative Medicine – Video

Wednesday, January 23rd, 2013


OTT: Breakfast Club Winter 2012 - Human Stem Cells 3.0: The Holy Grail of Regenerative Medicine
Human Stem Cells 3.0: The Holy Grail of Regenerative Medicine Techid: 12022

By: EmoryUniversity

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OTT: Breakfast Club Winter 2012 - Human Stem Cells 3.0: The Holy Grail of Regenerative Medicine - Video

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Stan Wang talks about creating non-embryonic stem for use n regenerative medicine – Video

Wednesday, January 23rd, 2013


Stan Wang talks about creating non-embryonic stem for use n regenerative medicine
Gates Cambridge Scholar Stan Wang is pursuing a PhD in medicine supervised by recent Nobel Prize winner Sir John Gurdon. Stan works on a technique which takes tissue from any part the human body and gives it embryonic stem cell-like properties. This could have a huge impact on the world of regenerative medicine.

By: GatesCambridge

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Stan Wang talks about creating non-embryonic stem for use n regenerative medicine - Video

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7.10 – Regenerative Medicine – Video

Tuesday, January 22nd, 2013


7.10 - Regenerative Medicine
Speaker: Ms. Elizabeth Sump, Director of Research Administration for the Orthopaedic and Rheumatology Institute, and Director of Governmental Relations, Cleveland Clinic and Dr. Fehmida Kapadia, Research Program Manager, Cleveland Clinic Ms. Sump is the Director of Research Administration for the Orthopaedic and Rheumatology Institute at the Cleveland Clinic, as well as a Director of Government Relations at Cleveland Clinic. She has previously served as the Executive Director of the Clinical Tissue Engineering Center, Chief Commercialization Officer of the Armed Forces Institute of Regenerative Medicine and Vice President of Corporate Development for NetGenics Inc., an enterprise bioinformatics company. A Cleveland native, Ms. Sump has been developing technology for the Healthcare and Life Sciences industries for nearly 25 years. Dr. Kapadia is a Research Program Manager at the Cleveland Clinic responsible for managing product development and commercialization of a device used to identify and isolate stem cells. Dr. Kapadia also manages the research being conducted to develop products for the treatment of wounded warriors as a part of an Armed Forces Institute of Regenerative Medicine research grant. Dr. Kapadia has a PhD in Biochemistry and a Master #39;s in Biotech Entrepreneurship. She has worked for several years in research labs conducting research in cardiovascular and molecular biology. Before joining the Cleveland Clinic, Dr. Kapadia worked at BioEnterprise which is ...

By: NEOinnovates

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7.10 - Regenerative Medicine - Video

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#33 – Tissue regeneration, stem cells, regenerative medicine – Video

Wednesday, January 16th, 2013


#33 - Tissue regeneration, stem cells, regenerative medicine
The ability of tissues to repair themselves is influenced by their capacity to regenerate the missing tissue and their ability that is inherent for them to divide and undergo mitosis. In most continuously dividing tissues the mature cells are terminally differentiated and short-lived. As mature cells die the tissue is replenished by the differentiation of cells generated from stem cells. Thus, in these tissues there is a homeostatic equilibrium between the replication and differentiation of stem cells and the death of the mature, fully differentiated cells. Regenerative medicine is the "process of replacing or regenerating human cells, tissues or organs to restore or establish normal function".

By: Kevin Mangum

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#33 - Tissue regeneration, stem cells, regenerative medicine - Video

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10 Reasons to attend the World Stem Cell

Friday, January 11th, 2013


10 Reasons to attend the World Stem Cell Regenerative Medicine Congress
Why should you attend? Watch the video to find out.

By: biopharmachannel

Excerpt from:
10 Reasons to attend the World Stem Cell

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Cell Therapy Blog welcomes 2013

Sunday, January 6th, 2013
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Happy new year to all our readers.  We look forward to our interactions throughout 2013. This month watch for:
We look forward to seeing you on the 2013 conference circuit.  For a complete and current list of 2013 cell therapy industry conferences, click here.

We will be in San Francisco next week during EBD Biotech Showcase and JP Morgan as well as at the Phacilitate Cell and Gene Therapy Forum in Washington, DC at the end of the month.

As always we welcome your comments, feedback, criticisms, and questions.

Thank you for all for everything to contributed to and did to support this blog and our efforts this past year.  Let's have a great 2013!


p.s.  Don't forget to follow Cell Therapy Blog on Twitter @celltherapyblog 

http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/ABphTtPOrwo/cell-therapy-blog-welcomes-2013.html

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Cell Therapy Blog welcomes 2013

Sunday, January 6th, 2013
Tweet 

Happy new year to all our readers.  We look forward to our interactions throughout 2013. This month watch for:
We look forward to seeing you on the 2013 conference circuit.  For a complete and current list of 2013 cell therapy industry conferences, click here.

We will be in San Francisco next week during EBD Biotech Showcase and JP Morgan as well as at the Phacilitate Cell and Gene Therapy Forum in Washington, DC at the end of the month.

As always we welcome your comments, feedback, criticisms, and questions.

Thank you for all for everything to contributed to and did to support this blog and our efforts this past year.  Let's have a great 2013!


p.s.  Don't forget to follow Cell Therapy Blog on Twitter @celltherapyblog 

http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/ABphTtPOrwo/cell-therapy-blog-welcomes-2013.html

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The Accuracy of Adipose Stem Cell Doses

Sunday, December 23rd, 2012
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In August we published a blog post, "Are some cell counts too good to be true? Why some companies' product data may mislead", pointing people to a white paper released by INCELL Corporation.  That white paper appears now to have been pulled from their website (we are working to get a copy to make available again) but now they have published a paper providing more detailed data on aspects of their comparative cell count study.


The paper is introduced by the following abstract:

"Cell therapy products derived from adipose tissue have some unique processing issues with regard to obtaining accurate cell counts. This is because processing methods may not only show us the nucleated stromal vascular fraction (SVF) cells but also the micellular and microvesicle particles. This is true for both veterinary and human clinical products, and poses special concerns for in-clinic processing where the cell therapy dose is correlated with cell numbers and other QC data is not especially useful.

In this study, multiple cell counting methods were compared for SVF cell reparation that were derived from canine adipose tissue using commercially-available rocessing kits. The data clearly showed that many non-nucleated particles appear cell-like by size and shape, and can lead to counting errors with automated counters. In addition, certain reagents important to processing can have properties wherein the reagents alone (e.g., lecithin) may be counted as cells. The most accurate cell numbers were from hemocytometer-counting of cells stained with 4´,6-diamidino-2-phenylindole (DAPI) which shows the nuclei in concert with a viability stain such as trypan blue. The data clearly showed that care must be taken when counting cells used as a therapeutic dose."

This is an important issue particularly as it pertains to autologous cell-based treatments produced by point-of-care devices and/or kits.  I encourage you to read the paper.   

Morrison DG, Hunt DA, Garza I, Johnson RA, Moyer MP*. Counting and Processing Methods Impact Accuracy of Adipose Stem Cell DosesBioProcess J, 2012; 11(4): 4-17.

* Dr. Moyer is CEO and Chief Science Officer for INCELL Corporation, 12734 Cimarron Path, San Antonio, Texas 78249 USA. http://www.incell.com

http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/z30UCNTkzIQ/the-accuracy-of-adipose-stem-cell-doses.html

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The Accuracy of Adipose Stem Cell Doses

Sunday, December 23rd, 2012
Tweet 


In August we published a blog post, "Are some cell counts too good to be true? Why some companies' product data may mislead", pointing people to a white paper released by INCELL Corporation.  That white paper appears now to have been pulled from their website (we are working to get a copy to make available again) but now they have published a paper providing more detailed data on aspects of their comparative cell count study.


The paper is introduced by the following abstract:

"Cell therapy products derived from adipose tissue have some unique processing issues with regard to obtaining accurate cell counts. This is because processing methods may not only show us the nucleated stromal vascular fraction (SVF) cells but also the micellular and microvesicle particles. This is true for both veterinary and human clinical products, and poses special concerns for in-clinic processing where the cell therapy dose is correlated with cell numbers and other QC data is not especially useful.

In this study, multiple cell counting methods were compared for SVF cell reparation that were derived from canine adipose tissue using commercially-available rocessing kits. The data clearly showed that many non-nucleated particles appear cell-like by size and shape, and can lead to counting errors with automated counters. In addition, certain reagents important to processing can have properties wherein the reagents alone (e.g., lecithin) may be counted as cells. The most accurate cell numbers were from hemocytometer-counting of cells stained with 4´,6-diamidino-2-phenylindole (DAPI) which shows the nuclei in concert with a viability stain such as trypan blue. The data clearly showed that care must be taken when counting cells used as a therapeutic dose."

This is an important issue particularly as it pertains to autologous cell-based treatments produced by point-of-care devices and/or kits.  I encourage you to read the paper.   

Morrison DG, Hunt DA, Garza I, Johnson RA, Moyer MP*. Counting and Processing Methods Impact Accuracy of Adipose Stem Cell DosesBioProcess J, 2012; 11(4): 4-17.

* Dr. Moyer is CEO and Chief Science Officer for INCELL Corporation, 12734 Cimarron Path, San Antonio, Texas 78249 USA. http://www.incell.com

http://www.celltherapyblog.com hosted by http://www.celltherapygroup.com

Source:
http://feedproxy.google.com/~r/CellTherapyBlog/~3/z30UCNTkzIQ/the-accuracy-of-adipose-stem-cell-doses.html

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