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Archive for the ‘Regenerative Medicine’ Category

Regenerative Medicine – BioTime, Inc.

Sunday, July 2nd, 2017

Regenerative medicine combines the latest advances in stem cell biology, embryology, tissue engineering and medicine to develop products for the replacement, restoration or regeneration of damaged or diseased cells and tissues. Tools used in regenerative medicine include biomaterials and extracellular matrices, lab-generated cells and tissues, and new biological molecules. These powerful technologies and tools are allowing clinical scientists to engineer and provide healthy cells, tissues and organs to patients with chronic degenerative diseases. This revolution in medical science changes the focus from treating symptoms of chronic and degenerative diseases to providing cures, and directly addresses costs that constitute approximately 83% of the 2.5 trillion dollar annual healthcare budget in the U.S. and are growing due to an aging population.

BioTime is led by Michael West, PhD., who pioneered the regenerative medicine industry. He founded Geron Corporation in the early 90s which funded the first studies of cultured hESC to realize their potential to cure intractable human degenerative diseases. Dr. West has since built BioTime around key technologies and intellectual property that constitute major pillars of regenerative medicine.

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5280 Stem Cell | Colorado Stem Cell Therapy

Sunday, July 2nd, 2017

Colorados Regenerative Medicine

5280 Stem Cell provides a comprehensive regenerative medicine program to reduce pain and improve vitality in patients suffering from chronic pain. Stem cells from your fat, blood or bone marrow heal damaged joints, spinal discs, ligaments, and tendons. Stem Cell Therapy heals the source of pain without the side-effects associated with invasive surgery and drugs.

Call us today at (720) 619-3144 to set up an appointment with our Physicians.

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How Can We Take Away Your Pain?

The 5280 Difference:

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Low-Risk Procedures

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Advanced Treatment Options

Four Convenient Locations in Colorado

Our Colorado regenerative medicine specialists are skilled in the areas of helping you heal from chronic pain. Using state-of-the-art technologies, such as amniotic, adipose, or bone marrow stem cell injections, PRP therapy, A2M, or hormone therapies, we have found great success for patients suffering from joint, back, musculoskeletal, or tissue damage.

All of our procedures are cash-based. Call us today to learn more.

Our Mission

To provide people with non-surgical treatment options that bring relief from pain, harness the bodys ability to heal itself, and restore hope for a healthier active future.

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New study on anemone genes could pave way for regenerative … – Yahoo News

Sunday, July 2nd, 2017

sea anemone heart gene regeneration regenerative medicine

In the future, artificial and transplanted organs may be things of the past as regenerative medicine becomes so advancedthat a damaged heart or lung is simply regrown from cells already present.

That possibility is still far in the distance, but a new study out of the University of Floridacould help pave the way. While examining the genes of the starlet sea anemone an invertebrate capable of regenerating itself a research team led by Mark Martindale discovered genes that are known to grow heart cells in humans.

The finding was surprising in part because anemones dont have hearts or muscles, and yet Martindale knew they shared more in common with humans than might be expected.

A group of us sequenced the genome of the anemone about 10 years ago, he told Digital Trends. One of the super cool things we found was that this little sea anemone had more genes in common with human beings than all of the other so-called model systems that 99 percent of the people in my field work on.

Since these model systems including fruit flies and nematodes are nearer to humans on the evolutionary timescale, that finding suggested that theyve lost genes along the way.

It turns out that the number of genes you have does not seem to be a very good predictor of organismal complexity as we have traditionally interpreted it, Martindale said.

Rather of the number of genes, the deciding factor may be the way they communicate with each other.

One of the most important findings in this paper is not necessarily how many genes are involved in heart formation, but how they are wired-up. Martindale explained. Genes control other genes in very complicated networks. Many people focus on genes that are involved in cell division but not as many people have studied the differences in how these genes talk to each other in animals that can regenerate versus those that can not regenerate.

By understanding how genes communicate, the researchers hope that they can someday stimulate regenerative healing in the human body.

But theres a lot of work to be done first. One of the big challenges will be determining whether certain mechanisms are species-specific or if they can be adapted. In vertebrates, for example, heart genes create lockdown loops that require them to perform functions related to their location in the body. Anemone genes dont lockdown in such a way. Its unclear whether this feature is fixed to anemone or if it can be activated in humans as well.

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Sea anemone genes could spur advancements in regenerative medicine – Digital Trends

Sunday, July 2nd, 2017

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Why it matters to you

The new finding could help scientists unlock the secrets to regenerative medicine in humans.

In the future, artificial and transplanted organs may be things of the past as regenerative medicine becomes so advancedthat a damaged heart or lung is simply regrown from cells already present.

That possibility is still far in the distance, but a new study out of the University of Floridacould help pave the way. While examining the genes of the starlet sea anemone an invertebrate capable of regenerating itself a research team led by Mark Martindale discovered genes that are known to grow heart cells in humans.

The finding was surprising in part because anemones dont have hearts or muscles, and yet Martindale knew they shared more in common with humans than might be expected.

A group of us sequenced the genome of the anemone about 10 years ago, he told Digital Trends. One of the super cool things we found was that this little sea anemone had more genes in common with human beings than all of the other so-called model systems that 99 percent of the people in my field work on.

Since these model systems including fruit flies and nematodes are nearer to humans on the evolutionary timescale, that finding suggested that theyve lost genes along the way.

It turns out that the number of genes you have does not seem to be a very good predictor of organismal complexity as we have traditionally interpreted it, Martindale said.

Rather of the number of genes, the deciding factor may be the way they communicate with each other.

One of the most important findings in this paper is not necessarily how many genes are involved in heart formation, but how they are wired-up. Martindale explained. Genes control other genes in very complicated networks. Many people focus on genes that are involved in cell division but not as many people have studied the differences in how these genes talk to each other in animals that can regenerate versus those that can not regenerate.

By understanding how genes communicate, the researchers hope that they can someday stimulate regenerative healing in the human body.

But theres a lot of work to be done first. One of the big challenges will be determining whether certain mechanisms are species-specific or if they can be adapted. In vertebrates, for example, heart genes create lockdown loops that require them to perform functions related to their location in the body. Anemone genes dont lockdown in such a way. Its unclear whether this feature is fixed to anemone or if it can be activated in humans as well.

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Center for Regenerative Medicine | Florida Orthopaedic …

Sunday, November 27th, 2016

By Name Armaghani, Sheyan J, M.D. Baker, Christopher E., M.D. Barna, Steven A., M.D. Beatty, Ellen , M.D. Bernasek, Thomas L., M.D. Billys, James B., M.D. Clare, Michael P., M.D. Davison, Thomas M., M.D. Echols, Jr., Eddy L., M.D. Epting, Timothy C., D.O. Frankle, Mark A., M.D. Garcia, Michael J, M.D. Garlick, Grant G, M.D. Gasser, Seth I, M.D. Grayson, Christopher W, M.D. Gustke, Kenneth A, M.D. Herscovici, Jr., Dolfi , D.O. Hess, Alfred V., M.D. Infante, Jr., Anthony F, D.O. Jackson, Howard B, M.D. Lyons, Steven T, M.D. Maxson, Benjamin J, D.O. Mighell, Mark A, M.D. Mir, Hassan R, M.D. Miranda, Michael A, D.O. Morse, Adam C, D.O. Nydick, Jason A, D.O. Palumbo, Brian T, M.D. Pappou, Ioannis P, M.D. Ramirez, Jr., John D., D.C. Reina, David A, D.C. Saatman, Donna A, M.D. Sanders, Roy W., M.D. Sellman, Jeff E, M.D. Shah, Anjan R, M.D. Small, John M., M.D. Stone, Jeffrey D, M.D. Tresser, Steven J., M.D. Walling, Arthur K., M.D. Watson, David T., M.D. Weinstein, Marc A., M.D. Yi, Seung Jin, M.D. Zaffer, Syed M., M.D.

By Specialty All Specialties Elbow Foot, Ankle & Lower Leg General Orthopaedics Hand & Wrist Hip & Thigh Interventional Spine Knee & Leg Musculoskeletal Oncology Primary Care Sports Medicine Shoulder Spine Sports Medicine Trauma

By Services All Services Chiropractic Services Concussion Treatment Physical Medicine & Rehabilitation Platelet Rich Plasma Therapy (PRP) Stem Cell Therapy Urgent Care at FOI

By Locations All Locations Bloomingdale Brandon Brooksville Citrus Park North Tampa - Temple Terrace Northdale Palm Harbor South Tampa Sun City Center Wesley Chapel

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Regenerative Medicine | The Future of Plastic Surgery …

Tuesday, November 15th, 2016

Regenerative medicine is the science of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal form and function. This broadly encompasses the use of cells, tissues, drugs, synthetic biomaterials, and devices to help patients heal more effectively from trauma, cancer therapy, other disease processes, and birth anomalies. Regenerative medicine therapies can have goals of both healing damaged tissues and forming new tissue.

While many clinicians and scientists across all fields of medicine have been involved in regenerative medicine research and clinical advances over the last two decades, plastic surgeons have been especially instrumental in moving new therapies into the clinical arena and having a leadership role in new scientific discoveries.

Areas of ongoing research and clinical care:

Burn care: Plastic surgeons have been pioneers in the use of protein scaffolds to generate the dermal layer, or innermost layer of the skin, following burn injury.

Nerve regeneration: Plastic surgeons, in the practice of hand and upper extremity surgery, as well as lower extremity surgery, are forging new paths in the science of regenerating nerves and restoring optimal function after nerve injury. These therapies involve the use of special growth factors to stimulate nerve healing, as well as special biomaterials to serve as guides to direct the growth of nerve fibers.

Breast reconstruction: Breast reconstruction is a vital part of cancer therapy for many women. Plastic surgeons are achieving better outcomes through the use of decellularized tissue scaffolds to regenerate new tissue layers over implants in breast cancer survivors.

Wound care: Complex wounds that are difficult to heal represent a major focus for tissue engineering and regenerative medicine strategies. Skin substitutes, composed of living cells grown in a laboratory, are used to heal these types of wounds. Additionally, growth factors are being explored for improving wound healing. One of the most significant breakthroughs in regenerative therapy for wound healing has been the use of negative pressure devices. Discovered by a plastic surgeon, these devices use negative pressure and micro-mechanical forces to stimulate wound healing.

Fat grafting and adipose stem cell therapy: A significant advance in surgical regenerative medicine has been the development and refinement of techniques to transfer fat tissue in a minimally invasive manner. This allows the regeneration of fat tissue in other parts of the body, using a patient's own extra fat tissue. This technique is revolutionizing many reconstructive procedures, including breast reconstruction. Importantly, fat tissue is an important source of adult mesenchymal stem cells. Discovered by plastic surgeons, adipose derived stem cells, are easy to isolate from fat tissue, and hold tremendous promise for treating many disorders across the body.

Scar treatment: Plastic surgeons are experts in the biology of scar formation and the molecular signals that impact healing. Regenerative therapies are being developed using energy-based devices, such as laser and intense pulsed light, to improve the healing of scars.

Hand and face transplantation: The ultimate in "Tissue replacement therapy," hand and face transplantation represents a life-restoring therapy for patients with severe trauma or other disease processes that result in loss of the hands or face. Most people aren't aware of this fact, but the very first successful human organ transplant was performed by a plastic surgeon. Dr. Joseph Murray performed the first kidney transplant in 1954. Plastic surgeons have been building up on his legacy in developing this new field of hand and face transplantation. This field also blends elements of cell therapy in order to control the immune response and reduce the need for toxic immunosuppressive drugs.

Bioprosthetic interfaces connecting humans and machine: This very interesting area of regenerative practice is directed at methods of connecting severed nerve endings with powered artificial limbs. This often involves "rerouting" the severed nerve endings to different muscles so that sensors over the skin can detect the signals and transmit them to a computer that controls the artificial limb.

Bone regeneration: For patients suffering extensive face or a limb trauma, large segments of bone may be missing. Plastic surgeons are using calcium based scaffolds and biomaterials derived from bone to form new bone tissue for reconstructive purposes.

"Custom made tissue flaps." For deformities that involve complex structures such as a major part of the nose, plastic surgeons are engineering new replacement parts at another site on the body. In a process called "flap prefabrication," the structure is assembled using tissue grafts and then transferred to the deformity after healing.

Generation of new skin by tissue expansion: Another technique pioneered by plastic surgeons is the use of gradual expansion of implanted balloon devices to generate new skin tissue that can cover a deformity. This technique is revolutionizing breast reconstruction and the treatment of many birth anomalies.

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Aegean Regenerative Medicine by Dr. Angelo Tellis

Tuesday, November 15th, 2016

Dr. Angelo Tellis Regenerative Medicine Specialist

Regenerative Medicine is an exciting new field of medicine that helps the body renew itself by using powerful natural agents like Platelet Rich Plasma and adult stem cells. It is much less invasive than surgery, which can often lead to even more tissue damage. It is all natural without placing any foreign substances in the body and has much less risk and downtime compared to surgery. Aegean Regenerative Medicine specializes in two different types of services including orthopedic and cosmetic procedures.

Orthopedic:Healing agents are delivered directly to the site of tissue injury. This restarts and maximizes the healing process in a natural way. New cartilage is formed, tendons and ligaments are repaired, and joints are restored.

Cosmetic:Tumescent Liposuction is performed for shaping and sculpting areas of the body while collecting adipose tissue rich in stem cells (Liposculpting). Stem cell rich adipose tissue can be combined with Platelet Rich Plasma to naturally enhance or augment other areas of the body (breasts, buttocks, hands, face, etc.) where desired (Lipotransfer).

Aegean Regenerative Medicine is available at Crystal Coast Pain Management offices located in New Bern, Morehead City and Jacksonville, North Carolina. Call 252-636-0300 to schedule a consultation with Dr. Tellis and explore your natural options.

Advantages Tumescent liposuction and breast enhancement in one procedure. All natural- nothing artificial is used. Safe and gentle procedure. Enhancement looks and feels like natural breasts. Future breast feeding not affected. Rapid recovery. Permanent, selective treatment of problem areas with smooth, even results. Virtually no scarring at insertion sites. Significantly reduced risk of complications. Comfortable outpatient procedure. Less bleeding, bruising and swelling.

Three locations to serve you Aegean Regenerative Medicine is located in Morehead City, New Bern, and Jacksonville, NC and operates under the Crystal Coast Pain Management system and supporting providers .

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Personalized Regenerative Medicine – Stem Cell Therapy San …

Monday, October 31st, 2016

DISCLAIMERS

ABOUT DR. STEENBOCKS TREATMENTS

Dr. Steenbocks clinic uses a combination of treatments in a unique approach which he calls Personalize Regenerative Therapy. The clinic usually combines multiple therapeutic modalities, including, stem cells (via bone marrow transplant), various medical devices (such as hyperbaric chambers, electrical pulse generator, IV medications (such as chelation) and proprietary nutritional supplements.

Most or all of these therapeutic modalities are given off-label, which means that while the drugs and devices are approved by the Federal Food and Drug Administration, these therapies have not been approved for your specific disease. Federal law permits physicians to make off label-use of drugs and devices based on their medical judgment.

Dr. Steenbocks use of these cutting-edge treatments and the combinations is based on his many years treating patients. His treatment approach would not be considered standard or conventional medicine, and are likely not offered any place else in the United States. Many of the diseases which Dr. Steenbock treats, such as ALS and Cerebral Palsy are considered incurable by conventional means.

Dr. Steenbock and his clinic do not and cannot promise to cure or even make better any patients disease or medical condition. Despite his best efforts, patients may not respond to his treatment approach, and in some cases, a patient may even get worse. Testimonials and patient stories contained in the web site are examples only and do not mean that a person with the same medical condition will achieve the same, similar or any beneficial result from the treatment.

ABOUT THE PURPOSE OF THIS WEB SITE

Medical information or statements made within this site are not intended for use in or as a substitute for the diagnosis or treatment of any health or physical condition or as a substitute for a physician-patient relationship which has been established by an in-person evaluation of a patient. This website does not provide specific medical advice and does not endorse any medical or professional service or services obtained through information provided on this site or any links to or from this site. This information and advice published or made available through this website is not intended to replace the services of a physician or a health care professional acting under a physicians supervision, nor does it constitute a doctor-patient relationship. Each individuals treatment and/or results may vary based upon the circumstances, the patients specific situation, as well as the health care providers medical judgment and only after further discussion of the patients specific situation, goals, risks and benefits and other relevant medical discussion. Testimonials or statements made by any person(s) within this site are not intended to substitute for this discussion or evaluation or as a guarantee as to outcomes. Whether to accept any treatment by a patient should be assessed by the patient as to the risks and benefits of such procedures and only after consultation with a health care professional. Some links within this website may lead to other websites, including those maintained and operated by third parties. These links are included solely as a convenience to you, and the presence of such a link does not imply an endorsement or approval of the content of the linked site. Use of this site constitutes acknowledgement and acceptance of these limitations and disclaimers.

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Regenerative medicine – Wikipedia

Friday, October 28th, 2016

Regenerative medicine is a branch of translational research[1] in tissue engineering and molecular biology which deals with the "process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function".[2] This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs.[3]

Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and implanting them when the body cannot heal itself. If a regenerated organ's cells would be derived from the patient's own tissue or cells, this would potentially solve the problem of the shortage of organs available for donation, and the problem of organ transplant rejection.[4][5][6]

Some of the biomedical approaches within the field of regenerative medicine may involve the use of stem cells.[7] Examples include the injection of stem cells or progenitor cells obtained through directed differentiation (cell therapies); the induction of regeneration by biologically active molecules administered alone or as a secretion by infused cells (immunomodulation therapy); and transplantation of in vitro grown organs and tissues (tissue engineering).[8][9]

The term "regenerative medicine" was first used in a 1992 article on hospital administration by Leland Kaiser. Kaisers paper closes with a series of short paragraphs on future technologies that will impact hospitals. One paragraph had "Regenerative Medicine" as a bold print title and stated, "A new branch of medicine will develop that attempts to change the course of chronic disease and in many instances will regenerate tired and failing organ systems."[10][11]

The widespread use of the term regenerative medicine is attributed to William A. Haseltine (founder of Human Genome Sciences).[12] Haseltine was briefed on the project to isolate human embryonic stem cells and embryonic germ cells at Geron Corporation in collaboration with researchers at the University of Wisconsin-Madison and Johns Hopkins School of Medicine. He recognized that these cells' unique ability to differentiate into all the cell types of the human body (pluripotency) had the potential to develop into a new kind of regenerative therapy.[13][14] Explaining the new class of therapies that such cells could enable, he used the term "regenerative medicine" in the way that it is used today: "an approach to therapy that ... employs human genes, proteins and cells to re-grow, restore or provide mechanical replacements for tissues that have been injured by trauma, damaged by disease or worn by time" and "offers the prospect of curing diseases that cannot be treated effectively today, including those related to aging." [15] From 1995 to 1998 Michael D. West, PhD, organized and managed the research between Geron Corporation and its academic collaborators James Thomson at the University of Wisconsin-Madison and John Gearhart of Johns Hopkins University that led to the first isolation of human embryonic stem and human embryonic germ cells, respectively.[16]

Dr. Stephen Badylak, a Research Professor in the Department of Surgery and director of Tissue Engineering at the McGowan Institute for Regenerative Medicine at the University of Pittsburgh, developed a process for scraping cells from the lining of a pig's bladder, decellularizing (removing cells to leave a clean extracellular structure) the tissue and then drying it to become a sheet or a powder. This extracellular matrix powder was used to regrow the finger of Lee Spievak, who had severed half an inch of his finger after getting it caught in a propeller of a model plane.[17][18][19][dubious discuss] As of 2011, this new technology is being employed by the military on U.S. war veterans in Texas, as well as for some civilian patients. Nicknamed "pixie-dust," the powdered extracellular matrix is being used to successfully regenerate tissue lost and damaged due to traumatic injuries.[20]

In June 2008, at the Hospital Clnic de Barcelona, Professor Paolo Macchiarini and his team, of the University of Barcelona, performed the first tissue engineered trachea (wind pipe) transplantation. Adult stem cells were extracted from the patient's bone marrow, grown into a large population, and matured into cartilage cells, or chondrocytes, using an adaptive method originally devised for treating osteoarthritis. The team then seeded the newly grown chondrocytes, as well as epithileal cells, into a decellularised (free of donor cells) tracheal segment that was donated from a 51-year-old transplant donor who had died of cerebral hemorrhage. After four days of seeding, the graft was used to replace the patient's left main bronchus. After one month, a biopsy elicited local bleeding, indicating that the blood vessels had already grown back successfully.[21][22]

In 2009, the SENS Foundation was launched, with its stated aim as "the application of regenerative medicine defined to include the repair of living cells and extracellular material in situ to the diseases and disabilities of ageing." [23]

In 2012, Professor Paolo Macchiarini and his team improved upon the 2008 implant by transplanting a laboratory-made trachea seeded with the patient's own cells.[24]

On September 12, 2014, surgeons at the Institute of Biomedical Research and Innovation Hospital in Kobe, Japan, transplanted a 1.3 by 3.0 millimeter sheet of retinal pigment epithelium cells, which were differentiated from iPS cells through Directed differentiation, into an eye of an elderly woman, who suffers from age-related macular degeneration.[25]

Because a person's own (autologous) cord blood stem cells can be safely infused back into that individual without being rejected by the body's immune system and because they have unique characteristics compared to other sources of stem cells they are an increasing focus of regenerative medicine research.

The use of cord blood stem cells in treating conditions such as brain injury[26] and Type 1 Diabetes[27] is already being studied in humans, and earlier stage research is being conducted for treatments of stroke,[28][29] and hearing loss.[30]

Current estimates indicate that approximately 1 in 3 Americans could benefit from regenerative medicine.[31] With autologous (the person's own) cells, there is no risk of the immune system rejecting the cells.

Researchers are exploring the use of cord blood stem cells for a spectrum of regenerative medicine applications, including the following:

A clinical trial under way at the University of Florida is examining how an infusion of autologous cord blood stem cells into children with Type 1 diabetes will impact metabolic control over time, as compared to standard insulin treatments. Preliminary results demonstrate that an infusion of cord blood stem cell is safe and may provide some slowing of the loss of insulin production in children with type 1 diabetes.[32]

The stem cells found in a newborn's umbilical cord blood are holding great promise in cardiovascular repair. Researchers are noting several positive observations in pre-clinical animal studies. Thus far, in animal models of myocardial infarction, cord blood stem cells have shown the ability to selectively migrate to injured cardiac tissue, improve vascular function and blood flow at the site of injury, and improve overall heart function.[31]

Research has demonstrated convincing evidence in animal models that cord blood stem cells injected intravenously have the ability to migrate to the area of brain injury, alleviating mobility related symptoms.[33][34] Also, administration of human cord blood stem cells into animals with stroke was shown to significantly improve behavior by stimulating the creation of new blood vessels and neurons in the brain.[35]

This research also lends support for the pioneering clinical work at Duke University, focused on evaluating the impact of autologous cord blood infusions in children diagnosed with cerebral palsy and other forms of brain injury. This study is examining if an infusion of the child's own cord blood stem cells facilitates repair of damaged brain tissue, including many with cerebral palsy. To date, more than 100 children have participated in the experimental treatment many whose parents are reporting good progress.[36]

Another report published encouraging results in 2 toddlers with cerebral palsy where autologous cord blood infusion was combined with G-CSF.[37]

As these clinical and pre-clinical studies demonstrate, cord blood stem cells will likely be an important resource as medicine advances toward harnessing the body's own cells for treatment. The field of regenerative medicine can be expected to benefit greatly as additional cord blood stem cell applications are researched and more people have access to their own preserved cord blood. [38]

On May 17, 2012, Osiris Therapeutics announced that Canadian health regulators approved Prochymal, a drug for acute graft-versus-host disease in children who have failed to respond to steroid treatment. Prochymal is the first stem cell drug to be approved anywhere in the world for a systemic disease. Graft-versus-host disease, a potentially fatal complication from bone marrow transplant, involves the newly implanted cells attacking the patient's body.[39]

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Organogenesis.com – Science – Regenerative Medicine

Thursday, August 4th, 2016

Regenerative medicine is a multidisciplinary field involving biology, medicine and engineering. It combines the physical nature of a product with living cells.

"Tissue Regeneration," "Tissue Engineering" and "Regenerative Medicine" are related terms and are sometimes used interchangeably.

Where does regenerative medicine fit into modern medical practice? Current traditional approaches to treat medical diseases include:

These methods are all considered essential, but have their limitations. For example, drugs have unwanted side effects, prosthetics are not biologically active and do not integrate or remodel into the body, surgery is invasive, and organ transplantation is limited by donor availability and toxic immunosuppressive cocktails.

Regenerative medicine is an emerging approach in modern medicine as it delivers living tissue, stimulating the body's own natural healing process by activating the body's inherent ability to repair and regenerate. Innovative therapies are now available that aim to heal or reconstruct diseased tissue and support the regeneration of diseased or injured cells and organs.

Doctors use regenerative medicine to speed up healing and to help injuries that will not heal or repair on their own. Regenerative medicine may help heal broken bones, severe burns, chronic wounds, heart damage, nerve damage, and many other diseases.

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Regenerative Medicine Conferences | Europe | Worldwide …

Thursday, August 4th, 2016

The 5th International Conference on Tissue Engineering & Regenerative Medicine which is going to be held during September 12-14, 2016 at Berlin, Germany will bring together world-class personalities working on stem cells, tissue engineering and regenerative medicine to discuss materials-related strategies for disease remediation and tissue repair.

Tissue Regeneration

In the field of biology, regeneration is the progression of renewal, regeneration and growth that makes it possible for genomes, cells, organ regeneration to natural changes or events that cause damage or disturbance.This study is carried out as craniofacial tissue engineering, in-situ tissue regeneration, adipose-derived stem cells for regenerative medicine which is also a breakthrough in cell culture technology. The study is not stopped with the regeneration of tissue where it is further carried out in relation with cell signaling, morphogenetic proteins. Most of the neurological disorders occurred accidental having a scope of recovery by replacement or repair of intervertebral discs repair, spinal fusion and many more advancements. The global market for tissue engineering and regeneration products such as scaffolds, tissue implants, biomimetic materials reached $55.9 billion in 2010 and it is expected to reach $89.7 billion by 2016 at a compounded annual growth rate (CAGR) of 8.4%. It grows to $135 billion by 2024.

Related Conferences

International Conference on Cancer Immunology and Immunotherapy July 28-30, 2016 Melbourne, Australia; International Conference on Molecular Biology October 13-15, 2016 Dubai, UAE; 5th International Conference on Tissue Science and Regenerative Medicine September 12-14, 2016 Berlin, Germany; 6th World Congress on Cell & Stem Cell Research February 29-March 02, 2016 Philadelphia, USA; 5th International Conference and Exhibition on Cell and Gene Therapy May 19-21, 2016 San Antonio, USA; Tissue Niches & Resident Stem Cells in Adult Epithelia Gordon Research Conference, Regulation of Tissue Homeostasis by Signaling in the Stem Cell Niche August 7-12,Hong Kong, China; 10 Years of IPSCs, Cell Symposia, September 25-27, 2016Berkeley, CA, USA; The Company of Biologists Workshops: From Stem Cells to Human Development September 25-28, 2016Southbridge, MA, USA; World Stem Cells & Regenerative Medicine Congress May 18-20, 2016 London, UK; Notch Signaling in Development, Regeneration & Disease Gordon Research Conference, July 31-August 5, 2016Lewiston, ME, USA

Designs for Tissue Engineering

The developing field of tissue engineering aims to regenerate damaged tissues by combining cells from the body with bioresorbable materials, biodegradable hydrogel, biomimetic materials, nanostructures and nanomaterials, biomaterials and tissue implants which act as templates for tissue regeneration, to guide the growth of new tissue by using with the technologies. The global market for biomaterials, nanostructures and bioresorbable materials are estimated to reach $88.4 billion by 2017 from $44.0 billion in 2012 growing at a CAGR of 15%. Further the biomaterials market estimated to be worth more than 300 billion US Dollars and to be increasing 20% per year.

Related Conferences

6th World Congress on Cell & Stem Cell Research February 29-March 02, 2016 Philadelphia, USA; 5th International Conference and Exhibition on Cell and Gene Therapy May 19-21, 2016 San Antonio, USA; International Conference on Restorative Medicine October 24-26, 2016 Chicago, USA; International Conference on Molecular Biology October 13-15, 2016 Dubai, UAE; 2nd International Conference & Exhibition on Tissue preservation and Bio-banking August 18-19, 2016 Portland, USA; ISSCR 14th Annual Meeting 22-25 June, 2016San Francisco, California, USA; Keystone Cardiac Development, Regeneration and Repair (Z2) April 3 7, 2016Snowbird, Utah, USA; The Stem Cell NicheDevelopment & Disease May 22-26, 2016Hillerd, Denmark; EMBL Hematopoietic Stem Cells: From the Embryo to the Aging Organism, June 3-5, 2016Heidelberg, Germany; ISSCR Pluripotency: From basic science to therapeutic applications March 22-24, 2016 Kyoto, Japan

Organ Engineering

This interdisciplinary engineering has attracted much attention as a new therapeutic means that may overcome the drawbacks involved in the current artificial organs and organ transplantation that have been also aiming at replacing lost or severely damaged tissues or organs. Tissue engineering and regenerative medicine is an exciting research area that aims at regenerative alternatives to harvested tissues for organ transplantation with soft tissues. Although significant progress has been made in the tissue engineering field, many challenges remain and further development in this area will require ongoing interactions and collaborations among the scientists from multiple disciplines, and in partnership with the regulatory and the funding agencies. As a result of the medical and market potential, there is significant academic and corporate interest in this technology.

Related Conferences

International Conference on Restorative Medicine October 24-26, 2016 Chicago, USA; 5th International Conference and Exhibition on Cell and Gene Therapy May 19-21, 2016 San Antonio, USA; 6th World Congress on Cell & Stem Cell Research February 29-March 02, 2016 Philadelphia, USA; 5th International Conference on Tissue Science and Regenerative Medicine September 12-14, 2016 Berlin, Germany;2ndInternational Conference & Exhibition on Tissue preservation and Bio-banking August 18-19, 2016 Portland, USA;Phacilitate Cell & Gene Therapy WorldJanuary 25-27, 2016Washington D.C., USA;ISSCR Stem Cell Models of Neural Degeneration and DiseaseFebruary 1-3, 2016Dresden, Germany;Craniofacial Morphogenesis & Tissue RegenerationMarch 12-18, 2016California, USA;Keystone Stem Cells and Cancer (C1)March 6-10,Colorado, USA;Keystone Stem Cells and Regeneration in the Digestive Organs (X6)March 13 17Colorado, USA

CancerStem Cells

The characterization of cancer stem cell is done by identifying the cell within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. This stem cell which acts as precursor for the cancer acts as a tool against it indulging the reconstruction of cancer stem cells, implies as the therapeutic implications and challenging the gaps globally. The global stem cell market will grow from about $5.6 billion in 2013 to nearly $10.6 billion in 2018, registering a compound annual growth rate (CAGR) of 3.6% from 2013 through 2018. The Americas is the largest region of global stem cell market, with a market share of about $2.0 billion in 2013. The region is projected to increase to nearly $3.9 billion by 2018, with a CAGR of 13.9% for the period of 2013 to 2018. Europe is the second largest segment of the global stem cell market and is expected to grow at a CAGR of 13.4% reaching about $2.4 billion by 2018 from nearly $1.4 billion in 2013.

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6th World Congress on Cell & Stem Cell Research February 29-March 02, 2016 Philadelphia, USA; 5th International Conference and Exhibition on Cell and Gene Therapy May 19-21, 2016 San Antonio, USA; International Conference on Molecular Biology October 13-15, 2016 Dubai, UAE; 5th International Conference on Tissue Science and Regenerative Medicine September 12-14, 2016 Berlin, Germany;2ndInternational Conference & Exhibition on Tissue preservation and Bio-banking August 18-19, 2016 Portland, USA; Molecular and Cellular Basis of Growth and Regeneration (A3) January 10 14, 2016Colorado, USA; Phacilitate Cell & Gene Therapy World January 25-27, 2016Washington D.C., USA; ISSCR Stem Cell Models of Neural Degeneration and Disease March 13 17, 2016Dresden, Germany; Craniofacial Morphogenesis & Tissue Regeneration March 12-18, 2016California, USA; World Stem Cells & Regenerative Medicine Congress May 18-20, 2016 London, UK

Bone Tissue Engineering

Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centered on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy. The availability of growth factors and the expanding knowledge base concerning the bone regeneration with modern techniques like recombinant signaling molecules, solid free form fabrication of scaffolds, synthetic cartilage, Electrochemical deposition, spinal fusion and ossification are new generated techniques for tissue-engineering applications. The worldwide market for bone and cartilage repairs strategies is estimated about $300 million. During the last 10/15 years, the scientific community witnessed and reported the appearance of several sources of stem cells with both osteo and chondrogenic potential.

Related Conferences

5th International Conference on Tissue Science and Regenerative Medicine September 12-14, 2016 Berlin, Germany; 6th World Congress on Cell & Stem Cell Research February 29-March 02, 2016 Philadelphia, USA; 3rd2nd International Conference & Exhibition on Tissue preservation and Bio-banking August 18-19, 2016 Portland, USA; 5th International Conference and Exhibition on Cell and Gene Therapy May 19-21, 2016 San Antonio, USA; International Conference on Restorative Medicine October 24-26, 2016 Chicago, USA;10th World Biomaterials Congress May 17-22, 2016 Quebec, Canada;2016 TERMIS-EU Conference June 28- July1, 2016 Uppsala, Sweden; 2016 TERMIS-AP Conference Tamsui Town of New Taipei CityMay 23-28, 2016;2016 TERMIS-AM Conference September 3-6, 2016, San Diego, USA; Pluripotency: From basic science to therapeutic applications 22-24 March 2016 Kyoto, Japan

Scaffolds

Scaffolds are one of the three most important elements constituting the basic concept of regenerative medicine, and are included in the core technology of regenerative medicine. Every day thousands of surgical procedures are performed to replace or repair tissue that has been damaged through disease or trauma. The developing field of tissue engineering (TE) aims to regenerate damaged tissues by combining cells from the body with highly porous scaffold biomaterials, which act as templates for tissue regeneration, to guide the growth of new tissue. Scaffolds has a prominent role in tissue regeneration the designs, fabrication, 3D models, surface ligands and molecular architecture, nanoparticle-cell interactions and porous of the scaffolds are been used in the field in attempts to regenerate different tissues and organs in the body. The world stem cell market was approximately 2.715 billion dollars in 2010, and with a growth rate of 16.8% annually, a market of 6.877 billion dollars will be formed in 2016. From 2017, the expected annual growth rate is 10.6%, which would expand the market to 11.38 billion dollars by 2021.

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4th International Congress on Bacteriology and Infectious Diseases May 16-18, 2016 San Antonio, USA; 2nd World Congress and Expo on Applied Microbiology October 31-November 02, 2016 Istanbul, Turkey; International Conference on Infectious Diseases & Diagnostic Microbiology Oct 3-5, 2016 Vancouver, Canada; International Conference on Water Microbiology & Novel Technologies July 18-20, 2016 Chicago, USA; 5th International Conference on Clinical Microbiology and Microbial Genomics October 24-26, 2016 Rome, Italy; Annual Meeting of the German Society for Gene Therapy 12 - 13 March 2015 Vienna, Austria; International Bone-Tissue-Engineering Congress 8 - 10 October 2015. Stuttgart, Germany; Till & McCulloch Meetings October 26-28, 2015 Toronto, Canada; 9th International Symposium on Neuroprotection and Neurorepair April 19 to April 22, 2016 Magdeburg, Germany; Craniofacial Morphogenesis & Tissue Regeneration March 12-18, 2016California, USA

Tissue Regeneration Technologies

Guided tissue regeneration is defined as procedures attempting to regenerate lost periodontal structures through differential tissue responses. Guided bone regeneration typically refers to ridge augmentation or bone regenerative procedures it typically refers to regeneration of periodontal therapy. The recent advancements and innovations in biomedical and regenerative tissue engineering techniques include the novel approach of guided tissue regeneration and combination of nanotechnology and regenerative medicine.

Related Conferences

3rd International Conference on Gynecology & Obstetrics October 17-19, 2016 Dubai, UAE; 5th International Conference on Tissue Science and Regenerative Medicine September 12-14, 2016 Berlin, Germany; 6th World Congress on Cell & Stem Cell Research February 29-March 02, 2016 Philadelphia, USA; 2nd International Conference & Exhibition on Tissue preservation and Bio-banking August 18-19, 2016 Portland, USA; International Conference on Restorative Medicine October 24-26, 2016 Chicago; 2016 Annual Convention & Exposition June 6-9, 2016 Philadelphia, USA;3rd International Conference on BioTribology - ICoBT 2016 September 11-14, 2016 London, UK; International Symposium on Endovascular Therapy - ISET February 6-10, 2016Florida, USA; International Bone Tissue Engineering Congress October 810 , 2015Stuttgart, Germany

Regeneration and Therapeutics

Regenerative medicinecan be defined as a therapeutic intervention which replaces or regenerates human cells, tissues or organs, to restore or establish normal function and deploys small molecule drugs, biologics, medical devices and cell-based therapies. It deals with the different therapeutic uses like stem cells for tissue repair, tissue injury and healing process, cardiac stem cell therapy for regeneration, functional regenerative recovery, effects of aging on tissue repair/regeneration, corneal regeneration & degeneration. The global market is expected to reach $25.5 billion by 2011 and will further grow to $36.1 billion by 2016 at a CAGR of 7.2%. It is expected to reach $65 billion mark by 2024.

Related Conferences

World Congress on Human Genetics October 31- November 02, 2016 Valencia, Spain; 5th International Conference on Tissue Science and Regenerative Medicine September 12-14, 2016 Berlin, Germany; 2nd International Conference & Exhibition on Tissue preservation and Bio-banking August 18-19, 2016 Portland, USA; European Conference on Genomics and Personalized Medicine April 25-27, 2016 Valencia, Spain; 4th International Conference on Plant Genomics July 14-15, 2016 Brisbane, Australia; World Stem Cells & Regenerative Medicine Congress May 18-20, 2016 London, UK; 18th International Conference on Tissue Engineering and Regenerative Medicine Applications May 12 - 13, 2016 Amsterdam, Netherlands; 18th International Conference on Bone, Muscle and Joint Diseases February 25 - 26, 2016 London, UK; 2nd Conference on Tissue Engineering and Regenerative Medicine March 18 to 20, 2016 Los Angeles, USA;

Regenerative medicine

Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function. The latest developments involve advances in cell and gene therapy and stem cell research, molecular therapy, dental and craniofacial regeneration. Regenerative medicines have the unique ability to repair, replace and regenerate tissues and organs, affected due to some injury, disease or due to natural aging process. These medicines are capable of restoring the functionality of cells and tissues. The global regenerative medicine market will reach $ 67.6 billion by 2020 from $16.4 billion in 2013, registering a CAGR of 23.2% during forecast period (2014 - 2020). Small molecules and biologics segment holds prominent market share in the overall regenerative medicine technology market and is anticipated to grow at a CAGR of 18.9% during the forecast period.

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International Conference on Next Generation Sequencing July 21-22, 2016 Berlin, Germany; 5th International Conference on Computational Systems Biology August 22-23, 2016 Philadelphia, USA; 7th International Conference on Bioinformatics October 27-28, 2016 Chicago, USA; International Conference on Synthetic Biology September 28-30, 2015 Houston, USA; 4th International Conference on Integrative Biology July 18-20, 2016 Berlin, Germany; World Conference on Regenerative Medicine October 2123, 2015 Lepizig, Germany; World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases April 14-17 2016 Malga, Spain; Bioinspired Materials Gordon Research Conference June 5-10, 2016, Girona, Spain

Applications of Tissue Engineering

The applications of tissue engineering and regenerative medicine are innumerable as they mark the replacement of medication and organ replacement. The applications involve cell tracking and tissue imaging, cell therapy and regenerative medicine, organ harvesting, transport and transplant, the application of nanotechnology in tissue engineering and regenerative medicine and bio banking. Globally the research statistics are increasing at a vast scale and many universities and companies are conducting events on the subject regenerative medicine conference like tissue implants workshops, endodontics meetings, tissue biomarkers events, tissue repair meetings, regenerative medicine conferences, tissue science conference, regenerative medicine workshop, veterinary regenerative medicine, regenerative medicine symposiums, tissue regeneration conferences, regenerative medicine congress.

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World Congress on Human Genetics October 31- November 02, 2016 Valencia, Spain; 5th International Conference on Tissue Science and Regenerative Medicine September 12-14, 2016 Berlin, Germany; 2nd International Conference & Exhibition on Tissue preservation and Bio-banking August 18-19, 2016 Portland, USA; European Conference on Genomics and Personalized Medicine April 25-27, 2016 Valencia, Spain; 4th International Conference on Plant Genomics July 14-15, 2016 Brisbane, Australia; Biocatalysis (GRS) Gordon Research Seminar Jul 9-10, 2016 New England, UK; World Conference on Regenerative Medicine October 2123, 2015 Lepizig, Germany; 18thInternational Conference on Tissue Engineering and Regenerative Medicine Applications May 12 - 13, 2016 Amsterdam, Netherlands; International Bone-Tissue-Engineering Congress 8 - 10 October 2015. Stuttgart, Germany; Craniofacial Morphogenesis & Tissue Regeneration March 12-18, 2016California, USA.

Market Analysis in Regenerative Medicine:

There are strong pricing pressures from public healthcare payers globally as Governments try to reduce budget deficits. Regenerative medicine could potentially save public health bodies money by reducing the need for long-term care and reducing associated disorders, with potential benefits for the world economy as a whole.The global market for tissue engineering and regeneration products reached $55.9 billion in 2010, is expected to reach $59.8 billion by 2011, and will further grow to $89.7 billion by 2016 at a compounded annual growth rate (CAGR) of 8.4%. It grows to $135 billion to 2024. The contribution of the European region was 43.3% of the market in 2010, a value of $24.2 billion. The market is expected to reach $25.5 billion by 2011 and will further grow to $36.1 billion by 2016 at a CAGR of 7.2%. It grows to $65 billion to 2024.

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2ndInternational Conference & Exhibition on Tissue preservation andBio-bankingAugust 18-19, 2016 Portland, USA; European Conference on Genomics andPersonalized MedicineApril 25-27, 2016 Valencia, Spain;3rdInternational Conference onGynecology& Obstetrics October 17-19, 2016 Dubai, UAE; 5thInternational Conference on Tissue Science andRegenerative MedicineSeptember 12-14, 2016 Berlin, Germany; 6thWorld Congress on Cell &Stem Cell ResearchFebruary 29-March 02, 2016 Philadelphia, USA;18thInternational Conference on Bone, Muscle andJoint DiseasesFebruary 25 - 26, 2016 London, UK; 2ndConference on Tissue Engineering andRegenerative MedicineMarch 18 to 20, 2016 Los Angeles, USA;InternationalBone-Tissue-Engineering Congress 8 - 10 October 2015. Stuttgart, Germany; CraniofacialMorphogenesis& Tissue Regeneration March 12-18, 2016California, USA.

Market Analysis Report:

Tissue engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole organ. Regenerative medicine is not one discipline. It can be defined as a therapeutic intervention which replaces or regenerates human cells, tissues or organs, to restore or establish normal function and deploys small molecule drugs, biologics, medical devices and cell-based therapies

Currently it has emerged as a rapidly diversifying field with the potential to address the worldwide organ shortage issue and comprises of tissue regeneration and organ replacement. Regenerative medicine could potentially save public health bodies money by reducing the need for long-term care and reducing associated disorders, with potential benefits for the world economy as a whole.The global tissue engineering and regeneration market reached $17 billion in 2013. This market is expected to grow to nearly $20.8 billion in 2014 and $56.9 billion in 2019, a compound annual growth rate (CAGR) of 22.3%. On the basis of geography, Europe holds the second place in the global market in the field of regenerative medicine & tissue engineering. In Europe countries like UK, France and Germany are possessing good market shares in the field of regenerative medicine and tissue engineering. Spain and Italy are the emerging market trends for tissue engineering in Europe.

Tissue engineering is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole organ. Currently it has emerged as a rapidly diversifying field with the potential to address the worldwide organ shortage issue and comprises of tissue regeneration and organ replacement. A novel set of tissue replacement parts and implementation strategies had shown a great revolution in this field. Cells placed on or within the tissue constructs is the most common methodology in tissue engineering.

Regenerative medicine is not one discipline. It can be defined as a therapeutic intervention which replaces or regenerates human cells, tissues or organs, to restore or establish normal function and deploys small molecule drugs, biologics, medical devices and cell-based therapies

This field continues to evolve. In addition to medical applications, non-therapeutic applications include using tissues as biosensors to detect biological or chemical threat agents, and tissue chips that can be used to test the toxicity of an experimental medication. Tissue Engineering and Regenerative Medicine is the major field in Medicine, which is still under research and the advancements are maximizing day to day.

Regenerative Medicine-2015 is an engrossed a vicinity of cognizant discussions on novel subjects like Tissue Regeneration, Materials & Designs for Tissue Engineering, Stem CellTools to Battle Cancer, Bioreactors in Tissue Engineering, Regeneration & Therapeutics, Cord Blood & Regenerative Medicine and Clinical Medicine, to mention a few. The three days event implants a firm relation of upcoming strategies in the field of Tissue Science & Regenerative Medicine with the scientific community. The conceptual and applicable knowledge shared, will also foster organizational collaborations to nurture scientific accelerations.We bring together business, creative, and technology leaders from the tissue engineering, marketing, and research industry for the most current and relevant.

Berlin is one of the largest and most diverse science regions in Europe. Roughly 200,000 people from around the world teach, research, work and study here. Approximately 17 percent of all students come from abroad, most of them from China, Russia and the USA. Many cooperative programs link Berlins institutes of higher education with partner institutes around the world. Berlin is a city of science at the heart of Europe a city whose history of scientific excellence stems from its many important research institutions and its long track record of scientific breakthroughs. Berlin has numerous modern Technology Centers. Their science-oriented infrastructure makes them attractive locations for young, technology-oriented companies.

Germany places great emphasis on globally networked research cooperation. Many organizations support international researchers and academics: Today more than 32,000 are being supported with scholarships. Besides this, research funding in Germany has the goal of financing the development of new ideas and technologies. The range covers everything from basic research in natural sciences, new technologies to structural research funding at institutions of higher education. On the basis of geography, the regenerative medicine bone and joint market Europe hold the second place in the global market in the field of regenerative medicine & tissue engineering. The market growth is expected to reach $65 billion by 2024 in Europe. In Europe countries like UK, France, and Germany are possessing good market share in the field of regenerative medicine and tissue engineering. Spain and Italy are the emerging market trends for tissue engineering in Europe. As per the scope and emerging market for tissue engineering and regenerative medicine Berlin has been selected as Venue for the 5th International Conference on Tissue Science and Regenerative Medicine.

Meet Your Target MarketWith members from around the world focused on learning about Advertising and marketing, this is the single best opportunity to reach the largest assemblage of participants from the tissue engineering and regenerative medicine community. The meeting engrossed a vicinity of cognizant discussions on novel subjects like Tissue Regeneration, Materials & Designs for Tissue Engineering, Stem CellTools to Battle Cancer, Bioreactors in Tissue Engineering, Regeneration & Therapeutics, Cord Blood & Regenerative Medicine and Clinical Medicine, to mention a few. The three days event implants a firm relation of upcoming strategies in the field of Tissue Engineering & Regenerative Medicine with the scientific community. The conceptual and applicable knowledge shared, will also foster organizational collaborations to nurture scientific accelerations.Conduct demonstrations, distribute information, meet with current and potential customers, make a splash with a new product line, and receive name recognition.

International Stem Cell Forum (ISCF)

International Society for Stem Cell Research (ISSCR)

UK Medical Research Council (MRC)

Australian Stem Cell Center

Canadian Institutes of Health Research (CIHR)

Euro Stem Cell (ACR)

Center for Stem Cell Biology

Stem Cell Research Singapore

UK National Stem Cell Network

Spain Mobile Marketing Association

European Marketing Confederation (EMC)

European Letterbox Marketing Association(ELMA)

European Sales & Marketing Association (ESMA)

The Incentive Marketing Association (IMA Europe)

European Marketing Academy

Figure 1: Statistical Analysis of Societies and Associations

Source: Reference7

Presidents or Vice Presidents/ Directors of Associations and Societies, CEOs of the companies associated with regenerative medicine and tissue engineering Consumer Products. Retailers, Marketing, Advertising and Promotion Agency Executives, Solution Providers (digital and mobile technology, P-O-P design, retail design, and retail execution), Professors and Students from Academia in the study of Marketing and Advertising filed.

Industry 40%

Academia 50%

Others 10%

Figure 2: Target Audience

Technische University Munchen

University of Wrzburg

University Medical Center

University of Tubingen

Universittsklinikum Mnster

Technische Universitt Dresden

Leipzig University

University Medicine of Rostock

Institut fur Humangenetik und Anthropologie der Universitat

Otto-von-Guericke University

Hannover Medical School

Max Planck Institute

Figure 3: Top Universities in Germany

There are strong pricing pressures from public healthcare payers globally as Governments try to reduce budget deficits. Regenerative medicine could potentially save public health bodies money by reducing the need for long-term care and reducing associated disorders, with potential benefits for the world economy as a whole.The global market for tissue engineering and regeneration products reached $55.9 billion in 2010, is expected to reach $59.8 billion by 2011, and will further grow to $89.7 billion by 2016 at a compounded annual growth rate (CAGR) of 8.4%. It grows to $135 billion to 2024

The contribution of the European region was 43.3% of the market in 2010, a value of $24.2 billion. The market is expected to reach $25.5 billion by 2011 and will further grow to $36.1 billion by 2016 at a CAGR of 7.2%. It grows to $65 billion to 2024. [Source: Reference2]

Figure 4: Global Market Growth of Tissue Engineering and Regenerative Medicine

Figure 5: Industries associated with Tissue Engineering and Regenerative Medicine

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Regenerative Medicine Conferences | Europe | Worldwide ...

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IRM at UPenn – Institute For Regenerative Medicine – Phila

Thursday, August 4th, 2016

The Institute for Regenerative Medicine is based in the Smilow Center for Translational Research and extends across UPenns campus.

The links between medicine, engineering and veterinary science differentiate Penns Institute for Regenerative Medicine from other stem cell Institutes across the country.

The IRM promotes discoveries in stem cell biology and regeneration to generate new therapies that may alleviate suffering and disease.

When our interdisciplinary research and programs bring together individuals with broad interests and diverse backgrounds, our collaborations lead to greater advances.

Stem cell research is critical to developing new skin tissues and, ultimately, changing the way we care for devastating wounds.

At Penn, we're discovering real possibilities of future treatments for cardiac disease because we have the research and clinical expertise to make it happen.

Thursday - April 21, 2016

Finding could lead to better drugs for the many asthma patients who dont respond well to current medications PHILADELPHIAAsthma is an enormous public health problem that continues to grow larger, in part because scientists dont

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Wednesday - March 23, 2016

This spring, the BioEYES program celebrates a major milestone: It will serve its 100,000th student. That means in the 14 years since BioEYES began, 100,000 elementary, middle, and high school students from Philadelphia and four

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Wednesday - February 10, 2016

A study from researchers at The Childrens Hospital of Philadelphia may add new lines to the textbook description of how cancer cells divide uncontrollably and develop into tumors. Their study, published in Nature Communications, identifies

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IRM at UPenn - Institute For Regenerative Medicine - Phila

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Stem Cell Conferences | Stem Cell Congress | Regenerative …

Thursday, August 4th, 2016

Conference Series LLC International Conferences invites all the participants from all over the world to attend Annual Conference on Stem Cell and Regenerative Medicine during Aug 4-5, 2016 at Manchester, UK which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

Track 1:Stem Cell Therapy

Stem cell therapy is used to treat or prevent diseases by using stem cells. It has potential in a wide range of territories of potential and restorative examination. This treatment is by and large used to supplant or repair harmed cells or tissues . It additionally helps in transplanting immature microorganisms or giving medications that objective undifferentiated organisms as of now in the body. Undeveloped cell treatment is a rising innovation, the recovery of body part is not really another idea.

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Track 2:Stem cell

An undifferentiated cell of a multicellular creature which is fit for offering ascend to inconclusively more cells of the same sort, and from which certain different sorts of cell emerge by separation. The most entrenched and generally utilized undifferentiated organism treatment is the transplantation of blood foundational microorganisms to treat infections and states of the blood and invulnerable framework, or to restore the blood framework after medications for particular growths. Subsequent to the 1970s, skin undifferentiated organisms have been utilized to develop skin joins for patients with serious smolders on expansive territories of the body. Just a couple of clinical focuses can do this treatment and it is normally held for patients with life-debilitating blazes. It is likewise not a flawless arrangement: the new skin has no hair follicles or sweat organs. Research went for enhancing the strategy is continuous.

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Track 3:Stem cell treatment

The most entrenched and broadly utilized undifferentiated organism treatment is the transplantation of blood foundational microorganisms to treat illnesses and states of the blood and invulnerable framework, or to restore the blood framework after medicines for particular malignancies. Subsequent to the 1970s, skin undifferentiated organisms have been utilized to develop skin unites for patients with extreme blazes on substantial territories of the body. Just a couple of clinical focuses can do this treatment and it is normally held for patients with life-undermining smolders. It is additionally not an immaculate arrangement: the new skin has no hair follicles or sweat organs. Research went for enhancing the method is progressing.

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8thWorld Congress on Stem Cell ResearchMarch 20-22, 2017 Orlando, USA; 5th International Conference and Exhibition onCell and Gene TherapyMay 19-21, 2016 San Antonio, USA; InternationalConference on Restorative MedicineOctober 24-26, 2016 Chicago, USA; InternationalConference on Molecular BiologyOctober 13-15, 2016 Dubai, UAE; 2nd InternationalConference on Tissue preservation and Biobanking September12-13, 2016 Philadelphia USA;Conference on Cardiac Development, Regeneration and RepairApril 3 7, 2016 Snowbird, Utah, USA; TheStem Cell DevelopmentMay 22-26, 2016 Hillerd, Denmark;Hematopoietic Stem Cells: From the Embryo to the Aging Organism, June 3-5, 2016 Heidelberg, Germany; ISSCR Pluripotency: From basic science to therapeutic applications March 22-24, 2016 Kyoto, Japan

Track 4:Somatic Cell Therapy

Somatic cell treatment is the organization to people of autologous, allogeneic, or xenogeneic living cells which have been controlled or prepared ex vivo. Assembling of items for substantial cell treatment includes the ex vivo proliferation, development, choice. Substantial cell treatment is seen as a more moderate, more secure methodology since it influences just the focused on cells in the patient, and is not went on to future eras. Substantial quality treatment speaks to standard essential and clinical exploration, in which helpful DNA (either incorporated in the genome or as an outside episome or plasmid) is utilized to treat illness. Most concentrate on extreme hereditary issue, including immunodeficiencies, hemophilia, thalassaemia and cystic fibrosis. Such single quality issue are great possibility for substantial cell treatment.

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Track 5:Tissue Regeneration

Tissue Engineering is the investigation of the development of new connective tissues, or organs, from cells and a collagenous platform to create a completely useful organ for implantation over into the contributor host. Effective improvements in the multidisciplinary field of tissue building have created a novel arrangement of tissue new parts and execution approaches. Investigative advances in biomaterials, foundational microorganisms, development and separation components, and biomimetic situations have made special chances to manufacture tissues in the research facility from blends of designed extracellular networks cells, and organically dynamic particles.

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Track 6:Regeneration and Therapeutics

Tissue regenaration therapeutics, making foundational microorganisms for supportive application in regenerative pharmaceutical. Regenerative solution is to offer the body some help with recuperating itself more sufficiently. In regenerative pharmaceutical, cell, tissue and organ substitutes are made to restore normal limit that has been lost.

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Track 7:Tumour cell science

An irregular mass of tissue, tumours are a great indication of aggravation, and can be favourable or threatening. Tumour for the most part mirror the sort of tissue they emerge in. Treatment is likewise particular to the area and kind of the tumour. Benevolent tumours can once in a while essentially be overlooked, destructive tumours; choices incorporate chemotherapy, radiation, and surgery.

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Track 8:Stem Cell & Gene therapy

Gene therapy remains a fairly new and still experimental procedure for the treatment of disease. In addition stem cells are still a relatively new concept and remain a confusing and complicated technology that much of the public struggles to understand. The potential for stem cells to be used in gene therapies is however, a valid one that has important ramifications for treating a range of diseases, many of which currently have no cure.

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Track 9:Stem Cell Biomarkers

Stem Cell Biomarker is characterized as a quality or their proteins that are utilized to disengage and recognize immature microorganisms. The other approach to distinguish the undifferentiated organisms is by utilizing utilitarian assays.Molecular biomarkers serve as profitable apparatuses to arrange and segregate embryonic immature microorganisms (ESCs) and to screen their separation state by immunizer based systems. ESCs can offer ascent to any grown-up cell sort and in this way offer colossal potential for regenerative medication and drug revelation. Various biomarkers, for example, certain cell surface antigens, are utilized to dole out pluripotent ESCs

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Track 10:Stem Cell Biobanking & Tissue preservation

Biobanks play a crucial role in biomedical research. The wide array of biospecimens (including blood, saliva, plasma, and purified DNA) maintained in biobanks can be described as libraries of the human organism.he process by which a tissue or aggregate of cells is kept alive outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).

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Track 11:Stem Cell Technologies

Cell separation is the movement, while a cell changes starting with one cell sort then onto the next. Variety happens various times amid the advancement of a multicellular living being as it changes from a straightforward zygote to a perplexing arrangement of tissues and cell sorts. Separation proceeds in adulthood as grown-up undifferentiated organisms isolate and make completely separated girl cells amid tissue repair and amid typical cell turnover. Some separation happens in light of antigen introduction. Separation drastically changes a phone's size, shape, film potential, metabolic movement, and responsiveness to flags. These progressions are to a great extent because of very controlled changes in quality expression and are the investigation of epigenetics. With a couple of exemptions, cell separation never includes an adjustment in the DNA succession itself. Along these lines, diverse cells can have altogether different physical attributes in spite of having the same genome.

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Track 12:Stem Cell Nano-Technology

In recent years, the inter crossing of nanotechnology in stem cell biology and biomedicine has led to an emerging new research field, known as stem cell nanotechnology. Stem cell nanotechnology is defined as the application of nanotechnology in stem cells research and development, and it is characterized as highly rapid in development, highly interdisciplinary, and highly controversial.

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Track 14: Stem Cell Apoptosis and Signal Transduction

Self-reestablishment and multiplication of foundational microorganism populaces is controlled, to some degree, by affectation of apoptosis. The quantity of foundational microorganisms is thusly a harmony between those lost to separation/apoptosis and those increased through multiplication. Apoptosis of immature microorganisms is accepted to be a dynamic procedure which changes because of natural conditions.

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Track 15: Tissue science & Engineering

Tissue Science and Engineering employs physical, chemical, and biological factors to replace and/or improve biological functions of the cell. The interdisciplinary field of tissue engineering has been one of the most active and quickly expanding disciplines during the past two decades.

Global stem cell market is dominating the healthcare industry with its reliable and cost effective method of treatment with fewer side effects. Current market for cord blood therapeutics accounts for $6.5 billion, which is expected to grow at 33.4% CAGR from 2013-2020. Other segments of this market include - Adult stem cell and embryonic stem cells. Cord blood stem cell is the only type of stem cell that is stored in controlled condition due to its lower volume higher cell count feature. Storage service market is expected grow at 33.4% CAGR from 2013-2020.

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Track 16: Novel Approaches in GTR

GTR is defined as procedures that are used to regenerate the lost periodontal structure by using different tissue responses. Many methods are used for tissue regeneration by using different materials like collagen, calcium sulphate, poly tetra flouro ethylene, polyglactin etc.It has become a standard of care in Periodontology and also used in periapical surgery.

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Track 17: Potential Applications of Stem cell Therapy

Foundational microorganisms are utilized to recuperate the body , advance recuperation. It has more helpful potential applications. It is utilized as a part of Cell Replacement Therapy which is particularly intended to taget the specific organs.Improvements of medications that advance cell expansion and separationIt is likewise used to deliver foundational microorganisms from the patient's skin and blood utilizing Ips innovation

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Track 18:Regenerative Medicine and Market

Regenerative pharmaceuticals have the one of a kind capacity to repair , supplant and recover tissues and organs , influenced because of some harm , infection. These drugs are ability of restoring the usefulness of cells and tissues. These medications have wide appropriateness in treating degenerative scatters including dermatology, cardio vascular, neurodegenerative sicknesses.

Cell treatment is the quickest developing fragment of regenerative drug. This undeveloped cell treatment is making up the biggest part of this business sector.

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Track 19:Stem cell-Bioinformatics

Computational Biology, sometimes referred to as bioinformatics, is the science of using biological data to develop algorithms and relations among various biological systems. Bioinformatics groups use computational methods to explore the molecular mechanisms underpinning stem cells. To accomplish this bioinformatics develop and apply advanced analysis techniques that make it possible to dissect complex collections of data from a wide range of technologies and sources.

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Track 20:Biomaterial Engineering

Abiomaterialis any matter, surface, or construct that interacts with living systems. As a science,biomaterialsis about fifty years old. The study of biomaterials is calledbiomaterials science or biomaterials engineering. It has experienced steady and strong growth over its history, with many companies investing large amounts of money into the development of new products.

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Track 19: Ethics inStem cellResearch

Stem cell research offers incredible guarantee for comprehension fundamental systems of human improvement and separation, and additionally the expectation for new medications for maladies, for example, diabetes, spinal string damage, Parkinson's ailment, and myocardial localized necrosis. Be that as it may, human undifferentiated organism (hSC) explore likewise raises sharp moral and political debates. The induction of pluripotent undifferentiated organism lines from oocytes and fetuses is laden with question about the onset of human personhood. The reinventing of substantial cells to deliver affected pluripotent undifferentiated organisms maintains a strategic distance from the moral issues particular to embryonic foundational microorganism research. In any hSC research, in any case, troublesome situations emerge with respect to delicate downstream research, agree to give materials for hSC research, early clinical trials of hSC treatments, and oversight of hSC examination. These moral and approach issues should be examined alongside exploratory difficulties to guarantee that undifferentiated cell examination is done in a morally fitting way. This article gives a basic investigation of these issues and how they are tended to in current arrangements.

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With the trail of success of the previous conference, OMICS International hosted the 5thWorld Congress on Cell and Stem Cell Research during March 23-25, 2015, at Double Tree by Hilton Chicago - North Shore, Chicago, USA with the theme Advanced Approaches in Cell Science and Stem Cell Research. Benevolent response and active participation was received from the Editorial Board Members of OMICS Group Journals as well as from the Stem Cell researchers, scientists, doctors, students and leaders from the fields of Cell and Stem Cell Research, who made this event successful.

The meeting was carried out through various sessions, in which the discussions were held on the following thought provoking and cerebrating scientific tracks:

The conference was embarked with an opening ceremony followed by workshops symposiums and a series of lectures delivered by both Honorable Guests and members of the Keynote forum. The adepts who promulgated the theme with their exquisite talk were;

Dr. James L. Sherley, Asymmetrex LLC, USA

Dr. Ornella Parolini, International Placenta Stem Cell Society (IPLASS), Italy

Dr. Paul J. Davis, Albany Medical College, USA

Dr. Haval Shirwan, University of Louisville, USA

Dr. Diana Anderson, University of Bradford, United Kingdom

Conference Proceedings

Best Poster Awardees:

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Regenerative medicine consultation service – Mayo Clinic …

Thursday, August 4th, 2016

At Mayo Clinic, an integrated team, including stem cell biologists, bioengineers, doctors and scientists, work together and study regenerative medicine. The goal of the team is to treat diseases using novel therapies, such as stem cell therapy and bioengineering. Doctors in transplant medicine and transplant surgery have pioneered the study of regenerative medicine during the past five decades, and doctors continue to study new innovations in transplant medicine and surgery.

In stem cell therapy, or regenerative medicine, researchers study how stem cells may be used to replace, repair, reprogram or renew your diseased cells. Stem cells are able to grow and develop into many different types of cells in your body. Stem cell therapy may use adult cells that have been genetically reprogrammed in the laboratory (induced pluripotent stem cells), your own adult stem cells that have been reprogrammed or cells developed from an embryo (embryonic stem cells).

Researchers also study and test how reprogrammed stem cells may be turned into specialized cells that can repair or regenerate cells in your heart, blood, nerves and other parts of your body. These stem cells have the potential to treat many conditions. Stem cells also may be studied to understand how other conditions occur, to develop and test new medications, and for other research.

Researchers across Mayo Clinic, with coordination through the Center for Regenerative Medicine, are discovering, translating and applying stem cell therapy as a potential treatment for cardiovascular diseases, diabetes, degenerative joint conditions, brain and nervous system (neurological) conditions, such as Parkinson's disease, and many other conditions. For example, researchers are studying the possibility of using stem cell therapy to repair or regenerate injured heart tissue to treat many types of cardiovascular diseases, from adult acquired disorders to congenital diseases. Read about regenerative medicine research for hypoplastic left heart syndrome.

Cardiovascular diseases, neurological conditions and diabetes have been extensively studied in stem cell therapy research. They've been studied because the stem cells affected in these conditions have been the same cell types that have been generated in the laboratory from various types of stem cells. Thus, translating stem cell therapy to a potential treatment for people with these conditions may be a realistic goal for the future of transplant medicine and surgery.

Researchers conduct ongoing studies in stem cell therapy. However, research and development of stem cell therapy is unpredictable and depends on many factors, including regulatory guidelines, funding sources and recent successes in stem cell therapy. Mayo Clinic researchers aim to expand research and development of stem cell therapy in the future, while keeping the safety of patients as their primary concern.

Mayo Clinic offers stem cell transplant (bone marrow transplant) for people who've had leukemia, lymphoma or other conditions that have been treated with chemotherapy.

Mayo Clinic currently offers a specialty consult service for regenerative medicine within the Transplant Center, the first consult service established in the United States to provide guidance for patients and families regarding stem cell-based protocols. This consult service provides medical evaluations for people with many conditions who have questions about the potential use of stem cell therapy. The staff provides guidance to determine whether stem cell clinical trials are appropriate for these individuals. Regenerative medicine staff may be consulted if a doctor or patient has asked about the potential use of stem cell therapies for many conditions, including degenerative or congenital diseases of the heart, liver, pancreas or lungs.

People sometimes have misconceptions about the use and applications of stem cell therapies. This consult service provides people with educational guidance and appropriate referrals to research studies and clinical trials in stem cell therapies for the heart, liver, pancreas and other organs. Also, the consult service supports ongoing regenerative medicine research activities within Mayo Clinic, from basic science to clinical protocols.

Read more about stem cells.

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Regenerative Medicine – Biolife Solutions, Inc.

Friday, October 9th, 2015

Regenerative Medicine is the process of engineering living, functional cell and tissue-based therapies and administering these to patients to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects. Target diseases include cancers, diabetes, heart disease, ALS and target disorders include spinal/movement, hearing loss, vision loss, and neurological (i.e., stroke).

Nearly all currently available and development stage regenerative medicine products and therapies utilize biopreservation processes and products in the acquisition of source material, isolation and manipulation of specific cells, and storage and shipment of a final product dose to a patient location. System optimization is critical and biopreservation economics greatly impact product commercialization potential through shelf life impact on distribution, and clinical dose efficacy following preservation.

This market is comprised of nearly 700 commercial companies and numerous other hospital-based transplant centers developing and delivering cellular therapies such as stem cells isolated from bone marrow, peripheral and umbilical cord blood as well as engineered tissue-based products. MedMarket Diligence, LLC, estimates that the current worldwide market for regenerative medicine products and services is growing at 20 percent annually. We expect pre-formulated biopreservation media products such as our HypoThermosol and CryoStor to continue to displace home-brew cocktails, creating demand for clinical grade preservation reagents that will grow at greater than the overall end market rate.

We have shipped our proprietary biopreservation media products to over 200 regenerative medicine customers. We estimate that our products are now incorporated into 30 to 40 regenerative medicine cell- or tissue-based products in pre-clinical and clinical trial stages of development. While this market is still in an early stage, we have secured a valuable position as a supplier of critical reagents to numerous regenerative medicine companies and university based centers.

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Regenerative Medicine - Biolife Solutions, Inc.

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Regenerative Medicine – Transplant Center – Mayo Clinic

Thursday, October 1st, 2015

At Mayo Clinic, an integrated team, including stem cell biologists, bioengineers, doctors and scientists, work together and study regenerative medicine. The goal of the team is to treat diseases using novel therapies, such as stem cell therapy and bioengineering. Doctors in transplant medicine and transplant surgery have pioneered the study of regenerative medicine during the past five decades, and doctors continue to study new innovations in transplant medicine and surgery.

In stem cell therapy, or regenerative medicine, researchers study how stem cells may be used to replace, repair, reprogram or renew your diseased cells. Stem cells are able to grow and develop into many different types of cells in your body. Stem cell therapy may use adult cells that have been genetically reprogrammed in the laboratory (induced pluripotent stem cells), your own adult stem cells that have been reprogrammed or cells developed from an embryo (embryonic stem cells).

Researchers also study and test how reprogrammed stem cells may be turned into specialized cells that can repair or regenerate cells in your heart, blood, nerves and other parts of your body. These stem cells have the potential to treat many conditions. Stem cells also may be studied to understand how other conditions occur, to develop and test new medications, and for other research.

Researchers across Mayo Clinic, with coordination through the Center for Regenerative Medicine, are discovering, translating and applying stem cell therapy as a potential treatment for cardiovascular diseases, diabetes, degenerative joint conditions, brain and nervous system (neurological) conditions, such as Parkinson's disease, and many other conditions. For example, researchers are studying the possibility of using stem cell therapy to repair or regenerate injured heart tissue to treat many types of cardiovascular diseases, from adult acquired disorders to congenital diseases. Read about regenerative medicine research for hypoplastic left heart syndrome.

Cardiovascular diseases, neurological conditions and diabetes have been extensively studied in stem cell therapy research. They've been studied because the stem cells affected in these conditions have been the same cell types that have been generated in the laboratory from various types of stem cells. Thus, translating stem cell therapy to a potential treatment for people with these conditions may be a realistic goal for the future of transplant medicine and surgery.

Researchers conduct ongoing studies in stem cell therapy. However, research and development of stem cell therapy is unpredictable and depends on many factors, including regulatory guidelines, funding sources and recent successes in stem cell therapy. Mayo Clinic researchers aim to expand research and development of stem cell therapy in the future, while keeping the safety of patients as their primary concern.

Mayo Clinic offers stem cell transplant (bone marrow transplant) for people who've had leukemia, lymphoma or other conditions that have been treated with chemotherapy.

Mayo Clinic currently offers a specialty consult service for regenerative medicine within the Transplant Center, the first consult service established in the United States to provide guidance for patients and families regarding stem cell-based protocols. This consult service provides medical evaluations for people with many conditions who have questions about the potential use of stem cell therapy. The staff provides guidance to determine whether stem cell clinical trials are appropriate for these individuals. Regenerative medicine staff may be consulted if a doctor or patient has asked about the potential use of stem cell therapies for many conditions, including degenerative or congenital diseases of the heart, liver, pancreas or lungs.

People sometimes have misconceptions about the use and applications of stem cell therapies. This consult service provides people with educational guidance and appropriate referrals to research studies and clinical trials in stem cell therapies for the heart, liver, pancreas and other organs. Also, the consult service supports ongoing regenerative medicine research activities within Mayo Clinic, from basic science to clinical protocols.

Read more about stem cells.

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Tissue Engineering and Regenerative Medicine | National …

Thursday, October 1st, 2015

Cells are the building blocks of tissue, and tissues are the basic unit of function in the body. Generally, groups of cells make and secrete their own support structures, called extra-cellular matrix. This matrix, or scaffold, does more than just support the cells; it also acts as a relay station for various signaling molecules. Thus, cells receive messages from many sources that become available from the local environment. Each signal can start a chain of responses that determine what happens to the cell. By understanding how individual cells respond to signals, interact with their environment, and organize into tissues and organisms, researchers have been able to manipulate these processes to mend damaged tissues or even create new ones.

The process often begins with building a scaffold from a wide set of possible sources, from proteins to plastics. Once scaffolds are created, cells with or without a cocktail of growth factors can be introduced. If the environment is right, a tissue develops. In some cases, the cells, scaffolds, and growth factors are all mixed together at once, allowing the tissue to self-assemble.

Another method to create new tissue uses an existing scaffold. The cells of a donor organ are stripped and the remaining collagen scaffold is used to grow new tissue. This process has been used to bioengineer heart, liver, lung, and kidney tissue. This approach holds great promise for using scaffolding from human tissue discarded during surgery and combining it with a patients own cells to make customized organs that would not be rejected by the immune system.

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Regenerative Medicine – Colorado Clinic

Friday, September 25th, 2015

Colorado Clinic offers multiple regenerative medicine stem cell treatments. These treatments are provided as an outpatient by a Double Board Certified Doctor. Each treatment maintains minimal risk, with the possibility of providing repair and healing of injured tendons, ligaments, cartilage and muscle.

Click on the Treatments on the Left Tabs for more information.

Stem Cell Treatments at Colorado Clinic

Traditional therapies for osteoarthritis, ligament injury and tendonitis maintain certain commonalities. They help provide excellent pain relief, however, they do not alter the condition or help with the healing process. They act as an excellent band aid, but they do not REPAIR the problem!

The newest treatments for helping repair the damage involve Regenerative Medicine. The therapies are cutting edge and include stem cells, platelets, growth factors and cytokines.

Here is an example of what regenerative medicine offers. When a football player sustains a rotator cuff tendon injury, it may heal by itself in six to 10 weeks. Healing of damaged tendons or ligaments may occur naturally. However, it does not reach 100% strength like it was before.

With regenerative medicine, this situation may be very different. Healing of the rotator cuff injury may occur much faster, and it may reach 100% normal strength. This can help prevent future injury and get patients back on the field faster.

Regenerative treatments may permit patients to avoid or delay the need for surgery when it comes to all sorts of injury. The most common of these is degenerative arthritis. Joint replacement surgery is not without risk, therefore, stem cell treatments may help repair some of the cartilage damage while providing substantial pain relief.

With minimal risk, outpatient stem cell treatments offer a substantial upside. Make your appointment at Colorado Clinic today!

Amniotic Stem Cell Injections

Life comes from birth. Its one of the most commonly accepted rules in our society. But can the birth process offer even more? As research and science evolved over time, studies have shown that amniotic stem cells can have a revolutionary effect on the human recovery process.

First, lets look at what amniotic stem cells are. Stem cells are the basic components (cells) of our human body. One of their most amazing characteristic is that they can become almost any type of cell, from muscle to bone or skin cell.

Amniotic stem cells are obtained from the amniotic fluid, which is produced during a caesarean birth. During pregnancy, the amniotic fluid protects the fetus and it feeds it with the necessary supplements needed to sustain life and development. A while back, this fluid was normally discarded, but once researchers got to understand its amazing therapeutic benefits, now its collected and stored because of its high concentration of pluripotent stem cells.

Amniotic derived stem cell fluid comes from consenting donors and is processed at an FDA regulated lab. It is checked for all sorts of diseases prior to being accepted for use in others.

Although stem cells have been used for decades, regenerative therapy is fairly new, and sometimes pushes the boundaries of human imagination and perception. Following the use of amniotic stem cell injections, more evidence reveals exciting results in muscle repair and pain relief which has made amniotic stem cells possibly the holy grail in treatment.

Amniotic stem cell injections offer the ability to heal damaged tissue naturally. The tissue regeneration and repair properties of the amniotic stem cell fluid are an effective anti-inflamatory that relieves pain and contains natural growth factors that assist in healthy tissue growth. Moreover, the hyaluronic acid that is also in amniotic fluid is an important component of the joint fluid that helps cartilage growth. Amniotic fluid is also a great source of stem cells, found in a much higher concentration than the adult bone marrow. And just like when one uses their own stem cells, the use of amniotic fluid doesnt cause rejection or allergic reaction when injected into a patient.

Amniotic stem cell injections have been getting more attention since they have been openly used by prominent athletes with impressive results and even a few saved careers! The ability to safely and effectively treat painful and debilitating injuries and conditions of the knees, elbows, and shoulders without lengthy rehabilitation or recovery time isnt just appealing to professional athletes, but to anyone who wants relief from pain and to return to their favorite activities.

Initial small studies are showing that amniotic stem cell injections work well for the following indications: 1) Tendonitis 2) Ligament Injury 3) Arthritis 4) Sports Medicine Injuries 5) Cartilage Defects

Dr. Sisson at Colorado Clinic is an expert in regenerative medicine treatments. Call the practice today for an appointment!

Bone Marrow Derived Stem Cell Injections for Musculoskeletal Problems

What are Bone Marrow Derived Stem Cell Injections?

There are many types of stem cell injections that are currently in research mode. One type of stem cell injection currently used for many types of degenerative conditions is the bone marrow derived stem cell injection. This type of stem cell treatment is excellent for degenerative disc disease, joint arthritis, ligament injuries, spinal arthritis, and tendonitis. Studies have shown that therapy using regenerative treatment, such as bone marrow stem cell injections, work well for degenerative conditions.

Bone Marrow Derived Stem Cell Collection and Injection

Bone marrow derived stem cell injections are an outpatient procedure where a patients bone marrow is harvested. It is then processed and injected into the area of concern in the same setting. In bone marrow derived stem cell injections, collection is done in an outpatient procedure which takes about 30 minutes. The bone marrow derived stem cells are collected using a catheter and local anesthetic.

The bone marrow derived stem cells are removed from the body in the blood, circulated through a machine with the filtered blood, and returned to the patients body in the same procedure. The stem cells are filtered out of the blood using the aspheresis machine, which retains only the stem cells.

What is the Future of Bone Marrow Derived Stem Cell Injections?

The future of bone marrow derived stem cell injections is a bright one. There are two types of bone marrow stem cells that can be derived from the tissue composing the middle of the bones, mesenchymal, and hematopoietic stem cells. It is the hematopoietic stem cells that differentiate back into blood cells among other things, and the mesenchymal cells that differentiate into skeletal and vertebral tissues.

Bone marrow derived stem cell injections are showing excellent results for tendonitis, ligament injuries and degenerative arthritis. This can help produce great results for athletes and individuals who desire to avoid or delay the need for joint replacement surgery.

Dr. Sisson at Colorado Clinic is at the forefront of regenerative medicine treatments with stem cells. You will be in good hands!

PRP Therapy at Colorado Clinic

The Facts about PRP Injections

Platelet-rich (PRP) therapy is a form of therapy that is used for damage that occurs within the tendons, ligaments, and joints. This type of therapy works by stimulating repair within the areas that are damaged, while also providing pain relief for the area where the therapy is used. PRP therapy has been around for quite some time, but has only recently become a more common method of treatment for musculoskeletal conditions.

Due to the ease of application, and the very few side-effects present with PRP therapy, it is commonly replacing other treatments that are more invasive, such as surgical procedures.

What exactly is PRP Therapy?

PRP therapy is often called platelet-rich plasma therapy, and this type of therapy is provided in the form of an injection. Initially, about 30-60cc of blood is drawn from the patients arm. It is placed into a centrifuge machine and separates into several layers. The middle layer contains concentrated platelets and growth factors and is used in the treatment for injection into the problem area.

Your blood is composed of several different parts, and when the blood is put into a medical machine that spins it at a fast rate, the platelets are separated from the blood, collected, and then put into a vial in a concentrated amount. The collected platelets are then injected into the area that is damaged, which provides the pain relief and repairing effects for the area. This allows the patient to get the platelets and growth factors needed for healing, while also using the bodys own resources, which eliminates the possibility of side-effects occurring due to the body rejecting the injection that is made.

The platelets that are removed from the blood are the same ones within the blood that stick to one another when we are injured and the blood clots. While the blood as a whole is known to have great healing powers, the platelets are one of the most effective healing components of the blood. When injected into the different damaged areas of the body, they are able to call in stem cells, and also allow for regeneration of the soft tissue.

How does PRP Therapy Work?

When the PRP injection is made, the solution goes directly into the area that is damaged, and also into the areas surrounding the damage. The therapy is known to provide pain relief within a week for patients in up to 80% of cases, due to the ability ofthe injections to stimulate healing in the area at a much faster rate than what your body is able to provide. Platelet rich plasma also contains significant amounts of growth factors, and even severe damage can be healed over time with the use of this form of therapy.

Where can PRP be Used?

PRP therapy can be used in all of the joints within the body, and even areas of soft tissue that are damaged such as the shoulder, elbow, achilles, etc. This may include tendonitis, ligament injury or degenerative arthritis.

Platelet-rich plasma therapy at Colorado Clinic is offered by the top pain management and regenerative medicine doctor in Northern Colorado, Dr. Sisson. He has extensive experience with regenerative medicine including PRP therapy, make your appointment today!

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MetroMD

Friday, September 25th, 2015

MetroMD Institute of Regenerative Medicine provides consumers and Healthcare Providers opportunities to benefit from uniquely effective services and products belonging to a new branch of Twenty-First Century medicine called Regenerative Medicine.

The evidenced-based, new technologies of Regenerative Medicine address health & Cosmetic problems currently unresolved by conventional medical-surgical approaches.

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Regenerative medicine – Wikipedia, the free encyclopedia

Tuesday, July 21st, 2015

Regenerative medicine is a branch of translational research[1] in tissue engineering and molecular biology which deals with the "process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function".[2] This field holds the promise of engineering damaged tissues and organs via stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs.[3]

Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and safely implanting them when the body cannot heal itself. If a regenerated organ's cells would be derived from the patient's own tissue or cells, this would potentially solve the problem of the shortage of organs available for donation, and the problem of organ transplant rejection.[4][5][6]

Attributed to William Haseltine (founder of Human Genome Sciences),[7] the term "regenerative medicine" was first found in a 1992 article on hospital administration by Leland Kaiser. Kaisers paper closes with a series of short paragraphs on future technologies that will impact hospitals. One paragraph had Regenerative Medicine as a bold print title and stated, A new branch of medicine will develop that attempts to change the course of chronic disease and in many instances will regenerate tired and failing organ systems.[8][9]

Regenerative medicine refers to a group of biomedical approaches to clinical therapies that may involve the use of stem cells.[10] Examples include the injection of stem cells or progenitor cells obtained through Directed differentiation (cell therapies); the induction of regeneration by biologically active molecules administered alone or as a secretion by infused cells (immunomodulation therapy); and transplantation of in vitro grown organs and tissues (tissue engineering).[11][12]

From 1995 to 1998 Michael D. West, PhD, organized and managed the research between Geron Corporation and its academic collaborators James Thomson at the University of Wisconsin-Madison and John Gearhart of Johns Hopkins University that led to the first isolation of human embryonic stem and human embryonic germ cells.[13]

Dr. Stephen Badylak, a Research Professor in the Department of Surgery and director of Tissue Engineering at the McGowan Institute for Regenerative Medicine at the University of Pittsburgh, developed a process for scraping cells from the lining of a pig's bladder, decellularizing (removing cells to leave a clean extracellular structure) the tissue and then drying it to become a sheet or a powder. This extracellular matrix powder was used to regrow the finger of Lee Spievak, who had severed half an inch of his finger after getting it caught in a propeller of a model plane.[14][15][16][dubious discuss] As of 2011, this new technology is being employed by the military on U.S. war veterans in Texas, as well as for some civilian patients. Nicknamed "pixie-dust," the powdered extracellular matrix is being used to successfully regenerate tissue lost and damaged due to traumatic injuries.[17]

In June 2008, at the Hospital Clnic de Barcelona, Professor Paolo Macchiarini and his team, of the University of Barcelona, performed the first tissue engineered trachea (wind pipe) transplantation. Adult stem cells were extracted from the patient's bone marrow, grown into a large population, and matured into cartilage cells, or chondrocytes, using an adaptive method originally devised for treating osteoarthritis. The team then seeded the newly grown chondrocytes, as well as epithileal cells, into a decellularised (free of donor cells) tracheal segment that was donated from a 51 year old transplant donor who had died of cerebral hemorrhage. After four days of seeding, the graft was used to replace the patient's left main bronchus. After one month, a biopsy elicited local bleeding, indicating that the blood vessels had already grown back successfully.[18][19]

In 2009 the SENS Foundation was launched, with its stated aim as "the application of regenerative medicine defined to include the repair of living cells and extracellular material in situ to the diseases and disabilities of ageing." [20]

In 2012, Professor Paolo Macchiarini and his team improved upon the 2008 implant by transplanting a laboratory-made trachea seeded with the patient's own cells.[21]

On Sep 12, 2014, surgeons at the Institute of Biomedical Research and Innovation Hospital in Kobe, Japan, transplanted a 1.3 by 3.0 millimeter sheet of retinal pigment epithelium cells, which were differentiated from iPS cells through Directed differentiation, into an eye of an elderly woman, who suffers from age-related macular degeneration.[22]

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