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WASHINGTON, Dec. 5, 2019 /PRNewswire/ -- The Washington Innovation in Longevity Summit (WIN) happening here December 9-10 at the National Press Club and produced by Mary Furlong & Associates, is the only conference that brings together a highly curated audience focused on solutions, partnerships, best practices and trends driving the $7.6 trillion U.S. longevity economy. The event is unique in that it selects the top innovators in aging technology backed by leading longevity market investors to share insights, learn from and connect with the federal agencies, private companies,nonprofits and media as well as potential global partners seeking impactful and sustainable innovation to support longer lifespans worldwide.

"The longevity economy offers vast domestic and global potential for investors and entrepreneurs but there are challenges for entrants to the space," said Mary Furlong, executive producer of WIN and CEO of Mary Furlong & Associates. "Our summit is carefully curated to help attendees navigate regulatory, privacy and reimbursement issues and remain at the forefront of trends in aging while also helping innovators scale their solutions with the right U.S. and international partners."

Furlong added, "The private companies, federal agencies and nonprofits who attend also benefit by connecting with this curated collection of innovators. Since technology moves fast and so many players enter the space on a daily basis, it is a resource drain for organizations to meet with every start-up company so attending this conference cuts through the clutter to identify best of breed and pursue quicker yet quality partnerships."

Joining the notable keynote speakers Nancy LeaMond of AARP and George Vradenburg of UsAgainstAlzheimer's, will be an impressive line-up of panel speakers from the federal government: James Parker, senior advisor to the Secretary for Health Reform and director of the Office of Health Reform at the U.S. Department of Health & Human Services; Melanie Egorin, deputy health staff director, U.S. House of Representatives Committee on Ways and Means; Todd Haim, chief of the Office of Small Business Research, National Institute on Aging and Vijeth Iyengar, brain health lead and technical advisor to the Deputy Assistant Secretary

for Aging at the Administration for Community Living, U.S. Department of Health and Human

Services. They join lead investors in the longevity market, Dan Hermann, president and CEO, head of Investment Banking forZiegler Link-Age Longevity Fund and Jake Nice, principal,Nationwide Ventures; along with top aging technology entrepreneurs such as CareLinx, Posit Science, Ageless Innovation, PS Salon & Spa and 12 global companies from countries including Japan, Israel and Sweden.

"Through its small business programs, the National Institute on Aging at the National Institutes of Health provided more than $100 million in funding to start up organizations in FY 2019 alone," said Todd Haim, Ph.D., chief, NIA Office of Small Business Research. "For successful applicants, our programs are an excellent source of seed funding for the further development of innovations geared toward older adult health and well-being."

The full agenda and summit details are here. Summit registration is available here. Key sponsors for the Summit include: AARP, Ageless Innovation, CareLinx, Center for Aging + Brain Health Innovation, Sodexo, Thrive Alliance, Posit Science, Audio Cardio, LivPact, CarePredict, Stay Smart Care, LLC., AloeCare, Embodied Labs, Nationwide, It's Never Too Late, VitalTech and Home Instead.

About Mary Furlong & Associates For 17 years, Mary Furlong & Associates (MFA), headquartered in the San Francisco Bay area, has developed strategies for marketing and business development for companies focused on opportunities with the senior and baby boomer markets and the longevity economy. Dr. Furlong is the executive producer of three conferences annually: What's Next Boomer Business Summit, Silicon Valley Boomer Venture Summit, and Washington Innovation in Longevity Summit. She also co-produces What's Next Canada and is scheduled to add a fourth conference in Paris, France, focused on international aging.

Contact Information: Ben Adkins 230490@email4pr.com 502.619.4267

SOURCE Mary Furlong & Associates

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Federal Agencies, Nonprofits and Global Companies Connect with Tech Entrepreneurs, Investors at Innovation in Longevity Summit Convened in Nation's...

The age-old secret to a longer life really comes down to a healthy lifestyle including regular exercise, limiting alcohol intake, not smoking and eating a healthy balanced diet. Good nutrition is key to leading a healthy lifestyle. The foods a person eats gives the body information and materials they need to function properly. If a person eats too much food, or food that gives the body the wrong instructions, their risk of potentially life-threatening diseases increases and lifespan shortens. What is the best diet to help a person live a long, healthy life and reduce their risk of deadly diseases?

A study has been published in the JAMA Internal Medicine Journal and reignites debate around increasingly popular vegan diets amid conflicting medical advice and evidence over the impact of ones health.

The study found every three percent in calories form plant protein was found to reduce risk of death by 10 percent.

The figure rises to 12 percent for risk of dying from heart disease. By contrast, raising the share of animal protein in ones diet by 10 percent led to a two percent higher risk of death from all causes.

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Experts recommend eating more plant-based foods, such as fruits, vegetables and whole grains. Lean protein and low-fat dairy products are also recommended.

Numerous research suggests eating at least seven portions of fresh fruits and vegetables per day may lower the risk of dying from cancer by up to 15 percent.

Dr Mingyang Song said: Overall, studies have supported the importance of the sources of dietary protein for long-term health outcomes.

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How to live longer: This diet has been proven to help you live longer and stave off cancer - Express

Todays regional roundup: Turkey in a tizzy over NATO plans; Albania opens probe into deadly earthquake; Kazakhs and China; long-lived Azeris; and the Putin-Zelenskiy summit.10 December 2019

Ankara Threatens to Block NATOs Eastern Defense Plan

Poland will not stand for Turkey walking back its support for NATOs defense plan for Poland and the Baltics, an aide to President Andrzej Duda said yesterday. There is no going back from the decision made at the NATO summit last week, Krzysztof Szczerski told Reuters. After the summit, NATO Secretary General Jens Stoltenberg said Turkey had withdrawn its objections to the plan, although Turkish President Recep Tayyip Erdogan said Turkey expected support from the alliance in its fight against Syrian Kurdish forces it considers to be terrorists. Turkish Foreign Minister Mevlut Cavusoglu then escalated the rhetoric, saying, Ankara will block the plan until it receives a proposal for a defense plan for Turkey, which must be in line with the Turkish viewpoint on YPG, Euractiv quotes him as saying. The Syrian Kurdish YPG force is a main fighting arm of the U.S.-backed Syrian Democratic Forces, Reuters writes. Duda and Baltic defense ministers appeared to be more optimistic for a solution on the matter during the London summit, although Eastern European officials were cautious about the prospects for compromise, Euractiv writes.

Albania Counts the Toll of Deadly November Quake

The earthquake that hit Albania last month totally destroyed at least 261 buildings, Prime Minister Edi Rama said yesterday. Durres, the countrys second city, was worst hit by the 6.4-magnitude quake that struck in the early morning of 26 November. In Durres, 438 buildings are so badly damaged they must be demolished, Rama said. The quake claimed 51 lives, Xinhua reports. Some 500 engineers, along with experts from 11 countries, are inspecting the affected areas, Rama said. Last week, newly appointed Albanian Prosecutor General Olsian Cela said prosecutors in Durres had opened an investigation into who should be held responsible for the damage, Radio Tirana International reported. There are people who have violated the law and many have lost their lives. Responsibility will fall either [on] the builder or [on] the official. There will be no hesitation in any case, Cela said. The minister of state for relations with parliament, Elisa Spiropali, who is also the governments spokeswoman, said new neighborhoods will be built to replace damaged housing, RTI reports today. She also chided the media for spreading the lie that the state has no money for civil emergencies.

Two Ethnic Kazakhs Fight Deportation to China

Two ethnic Kazakhs from Chinas Xinjiang region are facing deportation from Kazakhstan in spite of warnings they could be tortured if returned to China. The men, Murager Alimuly and Qaster Musakhanuly, crossed into Kazakhstan illegally on 1 October and were given asylum seeker status at the end of the month, The Diplomat reported. But as RFE/RL writes, the deputy chief of Kazakhstans National Security Committee said last week that the pair, currently being held in pre-trial detention, will be deported. Three Kazakh opposition activists, Zhanbolat Mamai, Yrysbek Toqtasyn, and Tolegen Zhukeev, told the media yesterday the men will definitely face torture and possible death back in China. China is holding, by some estimates, a million or more Muslims in re-education camps in the predominantly Muslim Xinjiang region. Beijing has long accused the majority Uighur community in Xinjiang of Islamist and separatist tendencies. The few officials who have acknowledged the existence of the camp system say they are aimed at instilling loyalty to the regime, and deny reports that Muslims in the region are subject to persecution. Kazakhs are the second-largest Turkic-speaking community in Xinjiang, RFE writes.

Ukraine Summit Brings Scant Progress

Ukrainian President Volodymyr Zelenskiy rammed home his no-compromise position on autonomy for Russian-backed separatists in the aftermath of yesterdays meeting with the Russian, French, and German leaders. There were no new ideas on resolving the conflict in eastern Ukraine, although Zelenskiy and Russian President Vladimir Putin agreed another ceasefire in the contested Donbas region, the Financial Times writes. They made no progress on the question that has dogged peacemaking efforts throughout the nearly six years of conflict that of a special dispensation for separatist areas in the Donbas. Before elections can be held in those regions, Kyiv must regain control of their borders, Zelenskiy said at a briefing after yesterdays Paris summit, Ukraines broadcaster 112 reports. "For Ukraine, the border is a security issue; for Russia, it is a policy, he said, adding that he and Putin finally agreed on the need to talk further. The four leaders also agreed on removing all minefields, further exchanges of prisoners, and military disengagement from three areas by next March, according to the FT.

Visit Lerik, Where the Living is Easy

Azerbaijani researchers recently conducted a study of the countrys centenarians, hoping to shed light on the legendary longevity of people in some isolated areas. There are certain generations of long-living people, Sevinj Huseynova, lead researcher at the Azerbaijani Institute of Physiologys longevity laboratory, told Trend last spring, as cited by Baku-based Caspian News. If the ecological environment is good, the gene is not lost and is inherited. Inhabitants of three districts in the south, along with Nagorno-Karabakh, are longer-lived than those in and around Baku, the study found. People living in the Talysh Mountains in the southern Lerik district are famous for exceptionally long lives and Lerik town boasts the worlds only Museum of Longevity, according to CNN. This two-room exhibition was built in 1991 and renovated in 2010. Some exhibits claim to document the incredible 168-year life of shepherd Shirali Muslumov. His 95-year-old daughter, Halima Qambarova, said while she might not match his record, she at least hopes to live to the age of 150, like her grandfather, or 130, like her aunt, CNN writes. Lifespans also run long among indigenous groups in Russias North Caucasus republics, where the Ingush often live to 80, Russia Beyond has reported. On the western flank of the region, the Abkhaz are also famed for their healthful diet and long lives.

Compiled by Ky Krauthamer

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Around the Bloc - 10 December - Transitions Online

Longer life expectancy is found among those who do a certain activity. Scientists say it not only boosts life expectancy but reduces the risk of obesity, high blood pressure, high cholesterol, disability, type 2 diabetes, heart disease and cancer. It also improves aerobic endurance, heart function, balance and metabolism. Best of all it requires no equipment, free of charge and promises some stunning scenery along the way.

Numerous studies have proven that running has a lot of health benefits. In fact, running once a week could help a person live longer, according to a November 2019 study published in the British Journal of Sports Medicine.

The study examined and analysed available data about the health benefits of running and found that running, even just 50 minutes per week, was associated with a 27 percent lower risk of death from all causes, a 30 percent reduced risk of death from heart disease and a 23 percent lower risk of death from cancer.

READ MORE: How to live longer: Following this diet once a month could increase your life expectancy

Researchers of the study noted: Increased rates of participation in running, regardless of its dose, would probably lead to substantial improvements in population health and longevity.

Fourteen studies were analysed with more than 232,000 people whose health was tracked between 5.5 and 35 years.

The collective data showed that any amount of running was associated with a reduce risk of death from heart disease or cancer.

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The reason behind how running helps reduce risk of deadly diseases and premature death is unclear and the study doesnt establish cause and effect.

Even so, the study proves that any amount of running has major benefits to the body and overall health.

Previous studies have found that fast walking also has a myriad of physical and cognitive health benefits.

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How to live longer: This activity has been proven to boost life expectancy - Express

Purdue is looking for dogs to participate in a national study on the health and wellness of dogs.(Photo: provided by Purdue)

WEST LAFAYETTE, Ind. Purdue is looking for dogs. More specifically, your dog to volunteer as a participant in a national study that will be looking at the general health and wellness of dogs.

The Dog Aging Project is a collaboration between more than 40 scientists and researchers across the U.S. and will be looking at dogs of all breeds, mixes and ages. At Purdue, Audrey Ruple, an assistant professor of One Health Epidemiology in the College of Health and Human Sciences, is one the researchers leading the study and is hoping to recruit dogs from across Indiana.

Ruple, who is a veterinary epidemiologist specializing in dogs as a model of human health, said the goal of the study is to examine factors that maximize the health and longevity of dogs, which can be linked to the health and longevity of humans.

Humans and dogs have more in common than we might think sharing 650 million base pairs of genetic information with the canines which Ruple said makes the animals useful to study human disease processes. Dogs also have a sophisticated health care system, comparable to the human health care system.

Dogs are unique because they share our environment, Ruple said. They live in our homes, drink our water and sometimes eat our human food. We both have similarities, and we see a lot of similar diseases and health issues.

The Dog Aging Project will follow participating dogs to watch how different environmental and biological factors can affect longevity for the next 10 years, although the schedule could extend beyond that time. The research hopes to look at specifics that could affect longevity, including an individuals genome, proteome, microbiome, demographics and environmental factors.

Owners who nominate their dogs to participate in the study will complete a 200-question health and lifestyle survey as well as submit electronic medial records, likely through the dogs veterinarian. The study isnt limiting the types of dogs participating eitherdogs of all breeds, mixes and sizes are encouraged to participate.

Neither the dogs nor owners will be compensated for the research, butthere is no cost to participate. Researchers will be working closely with the primary care veterinarians of the dogs, who will be expected to visit for their regular annual examination.

Ruple said the study is a citizen scientist project, meaning the owners of participating dogs are considered to be research partners in the study.

The study is funded by a five-year grant from the National Institute of Aging, which is part of the National Institute of Health, as well as private donations.

The Dog Aging Project hopes to enroll tens of thousands of dogs to research by the end of 2020.

People can take a part in the scientific process, whether its for human health or dog health, Ruple said. Through this study, we can learn to not only be better stewards of their existence, but also for our own.

TO APPLY:For more information on the Dog Aging Project or to nominate your dog, visithttps://dogagingproject.org/

Emily DeLetter is a news reporter for the Journal & Courier. Contact her at (765) 420-5205 or via email at edeletter@jconline.com. Follow her on Twitter at @EmilyDeLetter.

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Purdue is looking for your dog to participate in a national scientific study. Here's how. - Journal & Courier

Dan Buettner, the man who popularized the idea that there are five "Blue Zones" around the world where people live some of the longest, healthiest, happiest lives, says that people living in those zones all share five common traits.

"It is this interconnected web of characteristics that keep people doing the right things for long enough, and avoiding the wrong things," Buettner said.

Blue Zone residents, whether they're home in Loma Linda, California; Ikaria, Greece; Okinawa, Japan; Sardinia, Italy; or Nicoya, Costa Rica, all eat very little meat. Instead, they subsist on a largely plant-based diet filled with beans, nuts, and cruciferous vegetables, which Buettner has written about in a new cookbook.

But that diet is only, at best, about 50% of the Blue Zones longevity equation.

"It's the scaffolding, this collagen," Buettner told Insider. "That keeps people eating the right way for long enough."

Here are the other four core principles that sustain life in the Blue Zones.

Dan Buettner pioneered the idea that the world includes five "Blue Zones." Crystal Cox/Business Insider

Going to the gym is not a Blue Zones tradition.

"They don't exercise," Buettner said. Instead, people in Blue Zones are "nudged" into movement in little bursts throughout the day, by force of habit and, also, necessity.

"They're walking, or they're in their garden, or they're doing things by hand," he said.

In Buettner's home state of Minnesota, he credits shoveling the walks in winter, digging, weeding, and watering a garden in the summer with keeping him spry.

"I don't have a garage door opener, I open it by hand," he said. "To the extent that I can, I use hand-operated tools."

He's turned the inside of his house into a little mini Blue Zone, too, where he's getting up and moving all year round.

"I put the TV room on the third floor," Buettner told me, "So every time if I want a snack, I'd go up and down stairs."

The technique is one he's honed by studying life in the Blue Zones.

"It's being mindful of how to engineer little bursts of physical activity," he said.

Research has shown that such little energetic busts throughout the day can do a lot for overall fitness. One study published in January showed that even 20 second-long, vigorous stair-climbing exercise "snacks" spread out over the course of a day can improve fitness.

"It's a reminder to people that small bouts of activity can be effective," lead study author Martin Gibala told Insider when his team's research came out. "They add up over time."

Gallo Pinto ("spotted rooster") is a traditional breakfast meal in Costa Rica, made from leftover rice cooked with beans. Beans and rice are a complete protein. Kevin Schafer / Getty Images

In Japan they call it "ikigai," and in Costa Rica it's a "plan de vida." The words literally translate to "reason to live," and "life plan," respectively, and both concepts help residents of the Blue Zones feel there's a reason to get up and do what needs to get done each morning.

Studies also suggestthat a sense of purpose in life is associated with fewer strokes and less frequent heart attacks among people with heart disease, as well as more use of preventive care.

One 2017 investigation from researchers at Harvard concluded that a sense of purpose in life is associated with better "physical function among older adults," including better grip strength and faster walking.

Good health and happiness can be contagious, and obesity can too.

In Japan's Blue Zone, people form social groups called "moai" to help them get through life.

"Parents cluster their children in groups of five, and send them through life together," as Buettner explained in a recent video. "They support each other, and share life's fortunes and woes."

The trend is not unique to the Japanese. In Loma Linda, California, Blue Zoners (many of whom are Seventh-day Adventists) are more likely to share vegetarian potluck meals than meet each other over a Chipotle burrito or McDonald's fries.

Buettner has created Blue Zones "Projects" across the US, where cities and towns enact policies that change the entire environment that people live in.

"We're genetically hardwired to crave sugar, crave fat, crave salt, take rest whenever we can," Buettner said. "We've just engineered this environment where you don't have to move. You're constantly cooled down or heated up ... and you cannot escape chips and sodas and pizzas and burgers and fries."

In cities from Minnesota to Texas, he's helped create healthier communities where policies favor fruits and vegetables over junk food, people form walking groups to move around town and shed pounds together, and many quit smoking, too.

All of this, he said, adds up to troupes of "biologically younger" people, who not only weigh less, but suffer fewer health issues as they age.

"At every decade, you have more energy," he said.

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'Biologically younger' people who defy their real age often have 5 things in common - INSIDER

World Longevity Economy Size Projections, current USD

AI for Longevity has more potential to increase healthy Longevity in the short term than any other sector. The application of AI for Longevity will bring the greatest real-world benefits and will be the main driver of progress in the widespread extension of healthy Longevity. The global spending power of people aged 60 and over is anticipated to reach $15 trillion annually by 2020. The Longevity industry will dwarf all other industries in both size and market capitalization, reshape the globalfinancial system, and disrupt the business modelsof pension funds, insurance companies, investment banks, and entire national economies.

Longevity has become a recurring topic in analytical reports from leading financial institutions such as CitiBank, UBS Group, Julius Baer, and Barclays. At the recent AI for Longevity Summit in London, top executives from Prudential, HSBC, AXA Insurance, NVIDIA, Microsoft, Babylon Health, Insilico Medicine, Longevity.Capital, Longevity Vision Fund, Juvenescence, Deep Knowledge Ventures, and the UK All-Party Parliamentary Group for Longevity came together to discuss the Longevity Industry. International policymakers and senior corporate executives shared learnings from Japan, Israel, Switzerland, the US, and the UK and exchanged ideas on beginning to work together in a new social contract to enhance global prosperity equitably.

The 7th Continent - 1 Billion People in Retirement Globally

Switzerland is one of the most longevity progressive countries in the world with both high investment in biotechnology and the capacity to integrate AI into its economic, financial, and healthcare systems. Switzerland has the potential to be a world leader in both the Global Longevity Industry and the 4th Industrial Revolution. There are currently 100 companies, 80 investors, 50 financial companies, 35 research labs, 20 precision medicine clinics, 15 nonprofits, and 10 governmental organizations in the Swiss Longevity Industry. Switzerland is in an excellent position to retain its leading position by focusing on the optimal assembly of its existing resources to transform the challenge of demographic aging into a national asset.

Switzerland has a large aging population and Swiss investment banks are acutely aware of the oncoming demographic challenge. Switzerland is one of the most efficiently regulated and supervised financial centers in the world and has been leading transformative developments emerging from the digitalization of its banking and financial sector. Longevity-progressive countries typically have large aging populations, and aging populations have two longevity-progressive benefits: voting power and spending power.

Longevity Industry in Switzerland 2019

The digitization of finance, and novel financial systems which treat Longevity as a dividend, will play an integral role in the Longevity economy. According to a recent report by Aging Analytics Agency, Switzerland has the elements necessary to become a leading Longevity financial hub, including factors such as a lean political system that facilitates rapid implementation of integrated government programs, a strong research environment for geroscience, a strong research and business environment for digital health, and most importantly, international financial prowess.

Switzerland has the ability to develop several Longevity specific programs over the next several years. One program is a Longevity progressive pension system and insurance company ecosystem that accounts for both population aging (which threatens to destabilize the current business models of insurance companies and pension funds) and the potential for widespread healthspan extension. Another program is a national strategy for intensively developing Geroscience and FinTech to a state so advanced that it propels Switzerland into a central role in the international Longevity business ecosystem and a global leader in Longevity Finance. Switzerland is leading the digitization of financial markets and establishing itself as a catalyst for financial innovation on a global level. According to Aging Analytics Agency, 10% of all European FinTech enterprises are located in Switzerland.

Switzerland has a strong and productive geroscience community and has gained prominence among investors as a global biotech hub and hotbed of innovation. The Swiss Institute for Bioinformatics has recently identified large numbers of genetic markers directly linked to human life expectancy. Switzerland is also home to the prestigious Vontobel Prize for Aging Research.

The Convergence of 5 Mega Trends

BioValley

Switzerland is situated at one end of the BioValley - one of the leading life science clusters in Europe. This cluster is unique in that it spans across three countries, Switzerland, Germany and France, and includes Basel, a global life science hub. BioValley brings together important ingredients for a successful biotech cluster including a concentration of companies, rich availability of skills, experience within Life Sciences, and a world class research base. The cluster in Switzerland has in excess of 50,000 people working in the life sciences field including 15,000 scientists. There are 600 companies in the cluster developing therapeutic, diagnostic or medical devices to address a wide range of diseases in multiple therapeutic classes. There are 100,000 students enrolled in 10 universities and research institutions including University of Basel, Max Planck Institute, and Freiburg University. The cluster has produced a number of spin-out companies supported by a financial network including both public and private financing initiatives as well as traditional venture capital and private equity. The entire process of drug development is covered in the region, from research through to clinical and drug development, and manufacturing.

Longevity AI Consortium Expands to Switzerland

Longevity AI Consortium King's College London

In November 2019, Europes firstLongevity AI Consortium(LAIC)launched at King's College London. LAIC is currently developing collaborative research projects withDynamics of Healthy Ageing (DynAge)and theDigital Society Initiative (DSI)at the University of Zurich. The research will utilize AI technologies to predict the future cognitive ability of individuals using multimodal neuroimaging and risk factor data. Academics in Zurich will work in collaboration with colleagues at the Institute of Psychiatry, Psychology, and Neuroscience at King's College London. LAIC plans to establish several collaborative projects with the University of Zurich in 2020. The joint R&D between Ageing Research at Kings and University of Zurich forms the first phase of the global Longevity AI Consortium that will eventually be extended to Israel, Singapore, Japan and the US.

The Longevity Industry

AgeTech

FinTech banks are redefining the banking industry by connecting with a new generation of mobile-first consumers. However, FinTech banks are focusing on consumers who are middle-age and younger, not on the 1 billion people in retirement and the $15 trillion dollar market opportunity. As the share of the population over 60 increases, Swiss banks are lagging behind in finding solutions for this age group. Traditional banks, as opposed to challenger banks, are making their first steps in AgeTech, adapting their infrastructure for people over 60.

WealthTech

The WealthTech Industry refers to a new generation of financial technology companies that create digital solutions to transform the investment and asset management industry. New companies have arrived on the scene offering advice based on AI and big data, micro-investment platforms, and trading solutions based on social networks. A growing aging population is one of the main drivers of innovation in WealthTech. Financial services innovators have an opportunity to enhance the financial lives of individuals over 60 by designing new solutions and adapting existing products and services for them. This is an opportunity to implement innovations that address financial health challenges head on.

Financial Wellness

As a core component of its mission to develop Switzerland into a leading international Longevity Financial Industry hub, Longevity Swiss Foundation plans on roadmapping the development of AI Centers for Financial Wellness. Whereas the proposed AI Centers for Longevity would focus on optimizing health, these centers would focus on the application of AI to the creation of methods and technologies to promote wellness in other areas including financial wellness, continuing education, psychological well being, neuroplasticity, and active social involvement. The planned development of AI Centers for Financial Wellness will enable financial stability over extended periods of healthy Longevity for Swiss citizens.

Switzerland could become the center of the Longevity Financial Industry. Given its geographic size and its reliance on international cooperation, its function in the Longevity Industry will be as a small but important node. Due to its status as an international BioTech epicenter and its reputation as one of the most progressive countries in terms of its financial industry, the prospects for Switzerland to lead the world in the development of its Longevity Financial Industry are strong.

Today, change occurs at the intersection of two or more scientific and technological domains. We are at the beginning of a trend where the degree of complexity and the number of convergence points will increase exponentially. The convergence of AI, advanced data science, and Longevity research will accelerate important medical breakthroughs that will benefit all humans. In the next decade, the Longevity Industry will impact many areas of our lives. Longevity policies enacted by governments and changes in the global financial industry will transform society. Achieving small but practical results in Longevity distributed at scale will have enormous and multiplicative effects on society. Extending the functional lifespan of humans by just one year will decrease suffering for tens of millions of people and will improve the quality of life for billions of people.

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AI Will Drive The Multi-Trillion Dollar Longevity Economy - Forbes

In a recent study undertaken by scientists from the National Institutes of Health and National Institute of Aging, researchers found the secret to longevity is linked with meal times.

The researchers separated 292 male mice into two groups and gave them different diets. They also examined how altering the meal times affected the life expectancy of the mice. At the end of the study period, the scientists found the results to be very impressive and concluded that the same might be true for humans. happy man longevity Photo: rottonara - Pixabay

They said the findings provided a beacon of hope for future studies and at the same time, suggested a particular diet to help improve longevity. This study, which was participated in part by scientists from the Pennington Biomedical Research Centre and the University of Wisconsin-Madison, analyzed how longer fasting times could boost health and longevity. Researchers noted that increasing the time between meals improved the overall health of the male mice. They also lived longer compared to the other group who were fed and ate more frequently.

The scientists also report that health and life span greatly improved with increased fasting times, notwithstanding the type of food the mice ate or how many calories the food contained.Dr. Richard J. Hodes, a director at the NIA, said that the study revealed that the group of mice that consumed only one meal daily appears to enjoy a longer lifespan. They also seem to have better outcomes for age-related ailments like liver disease and a number of metabolic disorders.

He also said that the fascinating results using lab mice as the model which revealed the relationship of fasting and feeding time length and total caloric intake deserve a closer examination.

Dr. Rafael de Cabo, the studys lead author and Translational Gerontology Branch chief of the NIA Intramural Research Program, said increasing daily fasting times improved the overall health of male mice. He also said that their survival chances in a number of age-related ailments also increased. These positive results occurred regardless of the caloric intake and the type of diet the mice have.

The lead author hypothesized that the extended fasting period might have enabled the maintenance and repair mechanisms of the mices bodies to kick into place. Such a process would have been absent had the mice ate food continuously.Researchers of the study also revealed the results seem to suggest that those who are able to fast at least once a month may enjoy a longer and healthier life.

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You Can Improve Longevity By Having This Diet At Least Once A Month - International Business Times

Courtesy South Shore YMCA Ruth Kundsin, 103, works out with her personal trainer Dick Raymond at the South Shore YMCA in Quincy, Massachusetts.

People lifting weights at a gym in suburban Boston can be forgiven if they have no clue the energetic woman working out next to them is 103 years old.

Ruth Kundsins exercise routine includes cardio and strength training, a lifestyle thats more active now than the decades she spent working as a microbiologist only reluctantly retiring in her 80s.

She still lives on her own, loves parties and works out with a personal trainer every Friday at the South Shore YMCA in Quincy, Massachusetts.

I feel better afterwards and I think its keeping me vertical, Kundsin told TODAY, expressing surprise at all the excitement about her centenarian status.

Its really funny to me. I think Ive gotten more accolades for my age than I have for my science and thats sort of strange because you have nothing to do with your age. I mean, you just age, but the science I really worked hard on.

Dick Raymond, who has been her personal trainer for 10 years, said weights are the most important part of her routine.

We work every part of her body trying to keep her strong, Raymond, 69, noted. The older you get, the more you need exercise because you lose strength as you age. You can prevent that you can get better at any age.

Heres what Kundsin attributes to her longevity:

Kundsin described herself as having a very upbeat, optimistic, happy outlook on life. If something disturbs her, she gets over it, she said.

Its very important to have something to look forward to. If you dont have anything to look forward to, life is bleak and dull. But it seems like I always have something to look forward to and if there isnt anything, I make it, like I throw a party, Kundsin said.

I know that no matter how bad I feel, in a little while, Ill be feeling pretty good. I dont really worry about anything any great length of time.

The daughter of Latvian immigrants, Kundsin received a doctorate of science from Harvard School of Public Health in 1958.

Kundsin felt passionate about her work as a scientist and insisted on working even though it upset her family at a time when women were expected to stay home with their children.

She was the first mother to work in her community, facing intense scrutiny from her neighbors. Even Kundsins husband didnt want her to work, but she got her own way.

Thank goodness. Now I know it was the right thing to do, she said. Its a satisfaction to have a job I loved my work.

Kundsin had 150 papers published in scientific journals and wrote five books. She worked as an associate professor at Harvard Medical School until she was 81.

Scientific work is sedentary, so after spending much of her life bent over a microscope, Kundsin decided she had to make up for it when she retired.

When an acquaintance invited her to come to a gym, she thought it would be fun and has been exercising regularly ever since. She particularly liked swimming, taking part in Senior Games and competing at the national level three times.

She started working out with Raymond at age 93. The personal trainer focuses on having her do exercises that are challenging for her because challenging things are what improve you. Easy things dont improve you, he said.

Besides her weekly workouts, Kundsin cooks for herself and takes care of her house, doing chores and climbing up and down stairs, which Dick approves of, she said.

Kundsin isnt the first centenarian Raymond has worked with. He at one point also trained his father, who recently passed away at 101.

Unlike many centenarians TODAY has profiled, Kundsin smoked cigarettes for many years and didnt quit until her 70s. Still, she hasnt had any major health problems like cancer or heart disease, she said. Its only within the past year that shes started using a cane because of balance issues.

Kundsin doesnt eat beef, but otherwise does nothing special when it comes to her diet.

Influenced by Raymonds advice, she now eats oatmeal topped with lots of fruit for breakfast and has started avoiding sugar after a lifetime of eating desserts.

She drinks a glass of wine every night not because she loves it but because she believes its good for health. Indeed, research of people who lived to 90 and beyond found those who drank moderate amounts of alcohol lived longer than those who abstained.

I should be drinking red wine, but I think its a little strong for me so I drink white wine. I prefer champagne, Kundsin said.

Related Video: 104-Year-Old Runner Shares Her Longevity Tips (Provided by Today)

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103-year-old shares secrets to longevity: Exercise and wine - msnNOW

The secret to long life expectancy is to follow a healthy lifestyle - regularly exercising, limiting alcohol intake, not smoking and eating a healthy balanced diet. When it comes to eating a healthy diet, the NHS recommends eating at least five portions of a variety of fruit and vegetables every day, basing meals on higher fibre starchy foods like potatoes, bread, rice or pasta, having some dairy or dairy alternatives, some protein, choosing unsaturated oils and spreads, and eating them in small amounts, and drinking plenty of fluids. A new study also suggests a different approach to meal times and how it could impact on your health.

In the study with the National Institute of Ageing (NIA) and the National Institutes of Health, longer daily fasting times and how it could improve health and longevity was analysed. The study noted: Increasing time between meals made male mice healthier overall and live longer compared to mice who at more frequently. Scientists from the University of Wisconsin-Madison and the Pennington Biomedical Research Centre, Baton Rouge, Louisiana , reports that health and longevity improved with increased fasting time, regardless of what the mice ate or how many calories they consumed. https://www.sciencedaily.com/releases/2018/09/180906123305.htm

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NIA director, Dr Richard J. Hodes said: This study showed that mice who ate one meal per day and thus had the longest fasting period, seemed to have a longer lifespan and better outcomes for common age-related liver disease and metabolic disorders.

"These intriguing results in an animal model show that the interplay of total caloric intake and the length of feeding and fasting periods deserves a closer look.

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How to live longer: Following this diet once a month could increase your life expectancy - Express

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Long life study explores genetics of extreme longevity

A new grant from the National Institute on Aging of the National Institutes of Health (NIH) supports research into the mysteries of extreme longevity. Researchers at Washington University School of Medicine in St. Louis are leading the Long Life Family Study, which includes several generations of families with unusual concentrations of long-lived individuals. The goal is to uncover genetic factors that play roles in long life spans.

Washington University School of Medicine in St. Louis has received a $68 million grant to investigate and discover what contributes to extreme longevity. The researchers are studying hundreds of families over several generations with individuals who have had exceptionally long lives. Many of these families have unusual concentrations of people living to at least age 100.

The goal of the Long Life Family Study, funded by the National Institute on Aging of the National Institutes of Health (NIH), is to identify genetic factors that contribute to exceptional longevity. Such information could lead to new therapeutics or other health innovations to help people live longer, healthier lives.

These families provide a unique opportunity for finding genetic links to long life spans, said principal investigator Michael A. Province, PhD, a Washington University professor of genetics. Remarkably, many study participants in the older generations are unusually healthy for their ages. We think we will find clues in their DNA that suggest how they might be protected from common diseases, such as diabetes or Alzheimers disease or, at the very least, uncover genetic factors that might delay the onset of these health problems.

The School of Medicine is the coordinating center for the project, which has field centers at Boston University, Columbia University, the University of Pittsburgh and the University of Southern Denmark. Province and Mary K. Wojczynski, PhD, an assistant professor of genetics at Washington University, lead the primary site and coordinate collaborations among the field sites and the University of Minnesota, where the laboratory for analyzing blood samples is located.

The study includes almost 5,000 individuals from three generations of 539 families across the United States and Denmark, first recruited from 2006 through 2009. The average age of representatives of the oldest generation in the study was 90 at that time, with some individuals exceeding 110. Those in the second generation of these families now average over 70 years of age, and the grandchildren of the oldest group are now in their 50s, on average. Studying multiple generations of families with histories of long lives presents the opportunity to study individuals who have a greater chance of reaching older ages. In particular, it provides the ability to study such individuals when they are younger and not yet obviously different from those with shorter life spans.

When we study long-lived people, we would really like to be able to travel back in time and study them before they reach older ages to see how they might differ from the general population when those differences might not yet be obvious, Province said. Our earlier findings from this study have shown that individuals in the second generation are healthier, on average, than individuals from families with more typical longevity, when measured, for example, in middle age. But these healthier traits vary by family. For example, some long-lived families might tend to have lower blood pressure while others might have better cognition into later life, and still others might have better lung function or grip strength. Across these families, there is no single factor that stands out as the main reason for the long health and life spans.

The researchers suspect this variability may be linked to specific rare genetic variants that may protect such families from the harmful effects of aging in a variety of ways. The new funding will support whole genome sequencing of study participants in an effort to identify special protective variations in the DNA.

The researchers also will study the consequences of such differences in DNA through analyzing what effects they might have on the proteins, metabolites and other molecules that have a direct impact on the bodys biology. Such measures change with age, and the researchers are interested in comparing these with more average populations over their life spans. The comparison group is composed of participants from the well-known Framingham Heart Study, which has been tracking the health of multiple generations of families living in Framingham, Mass., since that study began in 1948. The researchers said less than 1% of families participating in the Framingham Heart Study meet the longevity criteria of the Long Life Family Study.

One genetic characteristic that stands out in some but not all long-lived families is the length of telomeres, or the end caps on chromosomes that protect the DNA from damage. Every time a cell divides, the telomeres get a little shorter, and shorter telomeres have been associated with chronic diseases, such as diabetes, heart disease, dementia and other disorders common among elderly people. Long-lived families seem to have longer than average telomeres.

Telomere length might be one key component of healthy aging, Province said. There is evidence that healthy behaviors like exercise can protect telomere length or even extend it. But there is a genetic component to it as well. Some people just naturally have longer telomeres, or at least appear to have resilient telomeres. And that is the case in many of the families were studying. Based on that data, we have honed in on a gene that could be involved in telomere length, and this new grant will help us explore that possibility and other new avenues further.

Washington University School of Medicines 1,500 faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Childrens hospitals. The School of Medicine is a leader in medical research, teaching and patient care, ranking among the top 10 medical schools in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Childrens hospitals, the School of Medicine is linked to BJC HealthCare.

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Families with long, healthy life spans focus of $68 million grant - Washington University School of Medicine in St. Louis

A plant-based diet underpins the health of those who live longest according to experts. Beans, legumes and pulses (such as lentils and chickpeas), compared with any other food, are the most important dietary predictor of longevity. They probably offer the best bang for your nutritional buck than any other food out there. David McLain

Wild greens like purslane, dandelion and arugula are a great source of minerals as well as carotenoids the colorful pigments our body converts to vitamin A. David McLain

Mushrooms, particularly shiitake, contain more than 100 compounds with immune-protecting properties. David McLain

Ginger's golden cousin is a powerful anticancer, antioxidant and anti-inflammatory agent. David McLain

Imo is a supercharged purple sweet potato that doesn't cause blood sugar to spike as much as a regular white potato. David McLain

Residents of Nicoya, Costa Rica -- a population more likely to reach a healthy 90 years old than anyone else on the planet -- use small sweet peppers in most of their dishes, and other peppers are also a staple food in longevity-prone Sardinia and Ikaria in Greece. Peppers are rich in vitamins, especially vitamin C. David McLain

Squash, available in several varieties, belongs to the botanical family Cucurbitaceae, known for providing high levels of useful carotenoids. David McLain

Nuts, as well as nut butters, are prominent in the diet of the Seventh-day Adventists, a religious group with a longer than average lifespan when compared to other Americans. One study found that those who ate a handful of nuts at least five times a week lived two to three years longer than those who didn't eat any nuts. David McLain

Ikarians in Greece drink tea brewed from local rosemary, wild sage and dandelion all of which are herbs known to have anti-inflammatory properties. David McLain

Lime-treated ground corn, or nixtamal, is used to make tortillas eaten at breakfast, lunch and dinner. It increases the body's ability to absorb calcium, iron and minerals. David McLain

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The ingredients to longevity - CNN

HERE IT IS just a few days after Thanksgiving, and Im probably not alone in thinking about the poundage I usually put on (then struggle to lose) in just one extremely treat-filled month. There is no doubt from the many studies on this topic about the relationship between weight and longevity in humans. While there are no studies of longevity in dogs that Im aware of, its likely the same relationship exists.

Longevity in dogs is a problem or rather lack of longevity. The American Veterinary Medical Association claims dogs are living longer. Longer than what? A hundred years ago, sanitation and medical improvements saved infants and the young from early death, greatly affecting human longevity. The claim that dogs are living longer might be related to the reduction and elimination of diseases that kill puppies. At the other end of the spectrum, the sad fact is that dogs do not live as long as they used to.

When I was a child, dogs often lived well into their teens. My next-door-neighbors dog, an Irish setter, was the same age as I. She died when I was a freshman in college. We were both 17. They also had a cocker spaniel that lived to be 20!

Nearly 50 years ago, I interviewed for a job at a Newfoundland kennel with more than 40 dogs, many that were 18 to 20 years old. They fully expected their dogs to live well into their mid-to late teens. Now, a mere 45 years later, a Newfie that lives to be 10 is old hardly an increase in longevity.

While genetics plays a role in longevity, there is a profound message for dog owners in this simple statement: Thin creatures live longer than fat ones.

Could it be that our pets reduced longevity is in part because we feed them too much? There is a lot we dont know about why so few dogs live into their late teens, but certainly one factor could well be excess weight even just a few too many pounds. A 50-pound dog that is just 10 pounds overweight is carrying 20% more weight than its frame and organs are designed for. This is considered to be obesity in humans, but in dogs its considered show weight or proof that we love and spoil our dogs usually said with an apologetic shrug.

If by spoiling our dogs were shortening their lives, wouldnt it be better to be tough (read kind) and cut out fattening snacks? Consider the greyhound, a large, sleek hound with a life expectancy many years beyond large, heavier hounds. Bloodhounds, a similar size, but much heavier dog, live to 10 or 11, while a greyhound often lives to 14 or 15. Greyhounds are one of the only show dogs for whom show weight is not overweight. You can see the ribs of a healthy greyhound, while it is often hard to even feel the ribs on many pet dogs.

I firmly believe that one of the reasons my English mastiffs lived to 13 or 14 (years beyond the life expectancy of the breed) was in part because I keep my dogs thin anathema for many mastiff people. For many giant breed owners, bigger is better. Theyll proudly exclaim, My Mastiff weighed 250 pounds! He might have died at the age of 6 and could barely walk because he was grossly overweight, but, by golly, he was huge!

Veterinarians we talk to almost universally agree that most pet dogs are too fat. In many cases, they have given up fighting that battle. Despite recommendations that the dog needs to lose weight, many owners seem to have a hard time cutting back on their dogs food and seem to believe theyre punishing their dog if they provide low-fat snacks. Youre not! Youre being kinder to your dog.

So in this holiday season, consider not sharing your turkey skin and leftover gravy with your dog. Or if you do, cut back on your dogs food that day. Your dog wont hate you for it, and you might well have him around a few extra months or years.

Gail Fisher, author of The Thinking Dog and a dog behavior consultant, runs All Dogs Gym & Inn in Manchester. To suggest a topic for this column, which appears every other Sunday, email gail@alldogsgym.com or write c/o All Dogs Gym, 505 Sheffield Road, Manchester, NH 03103. Past columns are on her website.

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Gail Fisher's 'Dog Tracks': Spoiling your dog with extra food could cut short its life - The Union Leader

With the rise of fad diets, so-called superfoods, and a growing range of dietary supplements on the market, it's hard to know what to eat to prevent dementia and increase our lifespan. But there is solid science behind the power of certain foods to protect your brain from oxidative damage and improve cognition and memory.

More and more studies are pointing to lifestyle changes to protect our brains from diseases including Alzheimer's. Noted expert Dr. Gary Small, author of "2 Weeks to a Younger Brain" and editor of The Mind-Body Health Report, tells Newsmax that according to researchers at the University of California at San Francisco, up to half the Alzheimer's cases are potentially attributable to "modifiable risk factors."

"In our book we focus on nutrition as well as stress management, physical exercise, and mental stimulation to keep the brain healthy and potentially delay the symptoms of dementia," says Small. In fact, studies have shown that sticking to the MIND diet is associated with 30 to 35 percent lower risk of cognitive impairment in older adults. The MIND diet, which stands for the Mediterranean-DASH Intervention for Neurodegenerative Delay, is a hybrid of both the famous Mediterranean and DASH diets.

As we age, our metabolism becomes less efficient and is less able to get rid of compounds generated from what is termed "oxidative stress." The toxic compounds generated by oxidative stress steadily build up, slowly damaging the brain and eventually leading to symptoms of Alzheimer's disease.

"Antioxidant fruits and vegetables protect the brain from oxidative stress, which causes wear and tear on our neurons as we age," notes Small. "Omega-3 fats from fish fight brain inflammation, helping us reduce the risk for age-related cognitive decline. Minimizing consumption of processed foods and refined sugars reduces the risk for diabetes, which further protects brain health throughout life."

Here are the five top foods to boost brain power:

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5 Foods to Boost Brain Health and Longevity - Newsmax

Somewhere in a coffee shop in America, some green-haired millennial is typing away feverishly on their brand new Macbook Air, broadcasting to their Twitter followers about how evil capitalism is. As they pour a dab of pasture-grazed New Zealand cows milk into their freshly roasted cup of Guatemalan organic free-trade coffee, they lament their woes to the world. Whycant society give me more? Why cant I enjoy success without hard work? On the other side of the globe, some hard workers in New Zealand are pulling off some prettymajor feats to put that delicious milk on the table.

It all starts at LIC, a New Zealand cooperative whose core business is dairy genetics. (Theyre responsible for inseminating 80% of New Zealands national dairy herd.) Next to LICs headquarters in Hamilton sit the prized bulls whove sired tens of thousands of calves. When the time comes, the bull is loaded into a custom tractor-trailer and taken to a building thats been there for decades. (The bull is transported this way so it doesnt stub its toe while walking over and consequently produce less sperm.) The bull is led up to an attractive cow who stands waiting while a human handler watches and waits. Once the bull convinces the cow that hes not just another player interested in a one-night stand, he mountsher, and this is where all the fun begins.

Collecting a jump Source: Livestock Improvement Corporation (LIC)

The human handler then needs to manipulate the bull with a device that collects the prized semen or a jump as its called in dairy lexicon. Once collected, some of the semen is frozen and shipped to various parts of the world. Its where life starts, and its a fitting place for a longevity company to start as well.

Founded in 2015, Hamilton, New Zealand startup Synthase Biotech has taken in$3.36 millionin funding and contributions to develop a platform technology that seems to have limitless promise. The technology behind the company came about as somewhat of an accident while researchers were looking for an alternative to latex when the Japanese were constraining supply. In an Arizona desert exists a shrub that contains latex that also contains an enzyme that prevents the latex from oxidizing. (Oxidization ishow a substance reacts to oxygen, and in some instances its not good like rust.) Its this plant enzyme that may, eventually, be used to increase longevity in humans.

Turns out that humans dont react well to prolonged exposure to oxygen over time. While oxygen is what you need to live, its also what can ultimately take you out in the end.Youve probably all heard of antioxidants which can prevent oxidative damage to cells and tissues by scavenging unconstrained radicals. Its damage that arises from unconstrained free radicals that can eventually be fatal. Synthase Biotech hasan enzyme that it calls Aloxsyn which has extraordinary specificity and rates of reaction against toxic lipid peroxides. In other words, this enzyme can be used to halt and even repair much of the damage that aspects of oxidization can do to mammalian cells, andthe company has developed a way to produce the enzymeusinga fermentation process.

We sat down to talk with Dr. Andrew West of Synthase Biotech, which has IP protection around the use of this enzyme, Aloxsyn, in their first product applications for frozen bull semen and cattle embryos.

Given how much work happens in Hamilton around frozen bull semen, it was a likely place to start. If a cow isnt fertile, its not producing milk. Consequently, you want to maximize cow fertility in order to maximize milk production. Keeping a cow that doesnt produce milk is uneconomic and produces unnecessary greenhouse emissions from its belching, or whatever it is theyre supposed to be doing thats wrecking the planet.

Ideally, fresh semen works best for artificial insemination, but there are many use cases where frozen semen is needed.You may need to transport the semen long distances, or you may want to preserve some semen from a prized bull to be used next year. When using frozen semen instead of fresh semen, fertility rates can drop as you might expect. However, when adding some Aloxsyn to the mix, you can get a better outcome. Thats based on a major trial that Synthase Biotech recently conducted.

If youre talking cattle, the final customer is always the farmer. Thats who Aloxsyn is helping. But its just one of many potential applications for this technology.

Synthases proprietary bioactive, Aloxsyn, may have a positive impact anywhere inflammationcan be found. Dr. West believes that the number of potential applications for the companys enzyme are very large. One application Synthase is looking at is storage of blood platelets, which will require some trial testing, but which represents a huge potential market. Then, there are more sperm applications.

Once a bull has a jump, that sperm dies almost immediately if it doesnt end up inside the cow where it belongs. Whilst working on frozen sperm, it looks like Aloxsyn also extendsthelife of fresh cattle sperm by five days. (LIC scientistsshowed us a proprietary solution theyre using that increases the life of cattle sperm by three days.) Why stop at cattle sperm? Fertility of pigs and horses could also be of interest as well, not to mention human fertility.

Source: Synthase Biotech

All of these fertility applications are higher margin, but there are also lower margin applications that can be considered such as increasing the shelf life of food. With around 30% of food waste in developed markets attributed to food spoilage, its another way that we may be able to help feed all the billions of mouths coming online. (Seems like a fitting application considering that theyre about increasing human fertility.) In order to address high-volume applications like this, production would need to be scaled and costs would need to be driven down. It all requires investment and partnerships with interested parties who want to collaborate.

No longevity companyis without some grand visions of what the future might hold. In some preliminary experiments, a rats heart was stopped from beating for 30 minutes and then blood applied with the enzyme. The rat heart recovered 100% of its function. A rat with a severe stroke could fully recover if Aloxsyn was applied within 45 minutes of that stroke. The implication here is an interesting one. Perhaps lipid peroxides in all thatbacked up blood behind the clot serve to damage the brain when the clot is overcome, and Aloxsyn cleans up those toxins? Its a promising example of what the future might hold, and if you have about $100,000 to pony up, Dr. West says Synthase Biotech will work to create a mouse that produces its own Aloxsyn, a mouse that just might live longer. Its a drop in the bucket forthe many billionairesout thereseeking the fountain of youth. For New Zealand investors, however, that sort of work is pretty risky.

The New Zealand Herald published a pretty comprehensive articleon Synthase Biotech last year which contains some relevant information about the state of biotech in New Zealand. Its dismal. Investorsdont look favorably on life sciences companies and that could be because the New Zealand stock exchange isnt of a size that would support them. (The entire New Zealand stock exchange has a market cap of just $142 billion. To put that number in perspective, Johnson & Johnson is over twice that size with a market cap of $363 billion.)

On the other hand, Australia is much more accepting towards biotechs with about 200 listings on the ASX. Synthase is not pursuing an ASX listing, but if the company moves into development of a human drug based on Aloxsyn, it will need millions of dollars for clinical trials. Significant investments over time will allow Synthase to add a range of human applications to complement its livestock ones. After a few years of selling animal products, their manufacturing operation will have all the kinks sorted out, andthats half the battle before embarking on some human trials.

The more we know about the world, the more we realize how little we know. Thats obvious when you consider how some of the worlds greatest inventions penicillin, X-rays, the microwave, LSD were all discovered by accident. The Peter Thiel types out there who are willing to sink large sums into theburgeoning longevity industrymight find the capital requirements for companies like Synthase Biotech to be more economical. According to a talk by Finistere Ventures a few years back, agtech valuations in the United Statesare half of fintech valuations, while New Zealand agtech valuations are half of that. If the fountain of youth exists inThe Land of the Long White Cloud, its likely to be selling at bargain-basement prices.

We thinkthis AI-powered weight loss app could be a multi-billion dollar business - not because it's backed by the world's most sophisticated investors- but because it works. If you want to lose weight and keep it off for good, check out Noom. People who use Noom lose weight and keep it off for good.

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Increasing Longevity by Decreasing Oxidization - Nanalyze

In a world where the rich always seem to get richer whatever the game, Social Security has always seemed to be one program that was truly progressive it benefited the working class more than the moneyed class. Right?

Sadly, no.

In reality, despite painstaking efforts to ensure that Social Security benefits are distributed fairly, the wealthy are receiving disproportionately large payouts after all. Thats the finding of a new study by Alicia H. Munnell and Anqi Chen of the authoritative Center for Retirement Research at Boston College.

Munnell and Chen, Boston College

The mismatch lurks within the adjustments made both when workers claim Social Security benefits early that is, before their full retirement age and late. Claim early, and monthly benefits will be reduced; claim late, and theyll be raised. These adjustments aim to make the timing decision actuarially neutral: On average, total lifetime benefits should remain equivalent whether one claims before ones full retirement age or later.

Munnell and Chen calculate that the actuarial adjustments are out of whack and favor late claiming. As a result, they increasingly favor higher earners, they write.

Sigh.

Munnell and Chen identify two culprits in throwing off the math: One is interest rates, which have been lower than experts at the Social Security Administration and on Capitol Hill anticipated when they set the differentials. (The early-retirement option was made available for women in 1956 and for men in 1961. The credit for delaying retirement was introduced in 1972 and recalculated in 1983, according to the authors.)

The second factor may be more significant: Average life expectancy is rising. As a result, retirees are collecting benefits for longer than the designers expected. Longevity is rising faster for wealthier individuals than middle- and lower-income workers, however, which is what makes late claiming more of a boon for the wealthy.

In the six decades since retirement options were broadened, Munnell and Chen write, Much has changed.... Interest rates have declined; life expectancy has increased; and longevity improvements have been much greater for higher earners.

Munnell and Chen assert that because of these two factors the penalty for early retirement is now too high. The bump up for delayed retirement is about right on average, they say, but because of the demographics favoring the wealthy, its too large for those who delay.

Before exploring the ramifications of these findings, lets look at how early and late retirement affect Social Security benefits.

Life expectancy has been rising for the wealthy faster than everyone else and the gap has broadened since the turn of the century.

(Boston College)

A Social Security reform measure in 1983 raised the full retirement age from the traditional 65 in incremental steps. For those born in 1943-54, including those reaching 65 this year, the full retirement age is 66. For those reaching 65 next year, it will be 66 and 2 months. The change tops out at age 67 for those born in 1960 or later.

Workers can start claiming benefits as early as 62, though monthly benefits are reduced by about 6.7% for every year prior to their full retirement. At the other end of the spectrum, workers can defer benefits until age 70, for a roughly 8% bump in monthly benefits for every year deferred.

Consider workers reaching 66 this year, when the average retirement benefit is $1,474.77 per month. Early retirement at 62 would reduce the monthly stipend by about 23%, while deferring until 70 would raise it by about 32%. So if those workers had started taking benefits four years ago, at age 62, theyd be entitled to only about $1,135.57 per month. If they hold out until 70, theyll get more than $1,947 a month. That means a reduction of about $4,000 a year for early retirement, and a gain of $5,667 a year for waiting.

For those expecting to collect the maximum benefit of $2,861 a month at full retirement age this year, early retirement at 62 would have reduced that to $2,209 a month, and deferral to 70 will raise it to $3,770.

Those figures explain the common advice to retirees is to wait as long as possible to start claiming. Of course, the advice isnt right for everyone. It does take more than 12 years of the higher maximum payouts after reaching age 70 to make up for the four years of skipped benefits after age 66, so retirees would need to factor their health expectations into the decision to wait.

More to the point, deferring Social Security isnt practical for many working people. Some are in jobs that are too physically taxing to continue too far into their 60s. Some dont have savings, pensions or other sources of income to live on. Indeed, among the top 20% of earners, just over half claim their retirement benefits at or after their full retirement age. Among the bottom 20%, however, nearly two-thirds claim early.

The salient point is that deferring Social Security tends to become a more inviting option the higher ones income and larger the nest egg. That advantage is compounded by such recipients longer average lifespans.

Wealthier workers are able to wait longer after their full retirement age (FRA) to start claiming Social Security benefits.

(Boston College)

As a research team led by economist Raj Chetty of Stanford reported in 2016, among the top 1% of earners (average household income of about $2 million), the average life expectancy is about 89 for women and 87.3 for men. Among the bottom 20% (average household income of about $25,000), the average life expectancy is about 83 for women and 78 for men.

The differential is based not only on income. Average life expectancy is higher for whites than for African Americans and rise with educational attainment.

As weve reported before, the longevity gap between rich and poor has been widening, largely because life expectancy for those in the bottom 20% has stagnated or even moved backward, while it has soared for those at the top.

The National Academy of Sciences calculated in 2015 that for those born in 1930, males in the bottom 20% who reached age 50 had a life expectancy of 76.6; those with the same characteristics born in 1960 could expect to live only to 76.1. Among the top 20% of income earners, males born in 1930 could expect to live to 81.7, while those born in 1960 could expect to live to 88.8. In other words, a longevity gap of just over five years between rich and poor born in 1930 widened to nearly 13 years for those born in 1960. A similar pattern can be found among women.

That trend line in itself made Social Security less progressive less advantageous for lower-income workers than for the better-off. It also undermined the argument that Social Security could be made fiscally healthier by continuing to raise the retirement age. It would, but at the expense of the working class. The National Academy of Sciences reckoned that raising the official retirement age to 70 would reduce the benefits of those in the lowest fifth of income earners by 25%, but by only 20% for those in the top fifth.

Munnell and Chen dont make specific recommendations about what adjustments should be made in the early- and late-retirement differentials, beyond stating that theyre outdated. Curiously this aspect of Social Security benefits is seldom, if ever, addressed by reform proposals from either left or right. (Progressives generally advocate expanding and raising benefits, while conservatives want to cut them or turn the entire program over to the private sector.)

Redressing the imbalance may not be that difficult. The early-retirement penalty should be recalculated -- that is, reduced -- based on the recent history of interest rates and changes in expectations for their future course.

Reducing the late-retirement credit, currently 8% per year of deferral, is somewhat more complicated. For the individual with average life expectancy, the reduction for early claiming is too large and the delayed retirement credit is about right, Munnell and Chen observe. The problem with the credit is that its right on average but too good for those who actually tend to receive it, i.e., the wealthy.

Finding a way to make the credit fair across the entire income spectrum may require some imagination. But the options could include increasing the income tax on Social Security benefits for high-income taxpayers. Currently, up to 85% of benefits are taxable for those with income of more than $34,000 for individuals or $44,000 for couples. (In other words, a taxpayers tax rate is applied to 85% of benefits, not that 85% of benefits is taxed away.) Tweaking that formula, say by making 100% of the benefits claimed by richer retirees subject to tax might help bring the credit effectively back into line.

The report by Munnell and Chen underscores the inequity bequeathed to Social Security by demographics. The wealthy not only live longer than their poorer colleagues, but they also get an additional windfall from outdated math. Thats how the world works, but that doesnt make it right.

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Column: The rich are getting a windfall from Social Security - Los Angeles Times

Alistair Overeem has been around for a long, long time. Of the course of a 20-year combat sports career, the Dutchman has picked up titles in Strikeforce, Dream, and K-1 and hes still not done yet.

Ahead of his upcoming showdown with Jairzinho Rozenstruik, which will top the UFCs December 7 return to Washington, D.C., Overeem sat down with UFC.com and opened up on the mindset that has kept him competing at the highest level for so long.

Part of it, he says, is simply being hard-wired with a fighters mentality a mentality hes always had.

I think Ive always been a fighter, Overeem said (via MMA Junkie). Ive always kicked ass even before I was professionally a fighter. Id have fights in the street and it even got me in trouble a couple of times.

Some people will never be fighters, and then some people are born fighters.

Overeem also attributes his longevity to his love for fighting.

I think us fighters go for amazing stories, Overeem said. My career in particular has been a long adventure. I think I was built for it. Ive been all over the world. Ive fought in 89 fights, kickboxing and MMA. Im just doing my thing. Im following my passion. Its been a great adventure and Im still going strong.

If Overeem is able to defeat Rozenstruik an undefeated fighter and one of the hottest prospects in the heavyweight division hell once again be close to a UFC heavyweight title shot. The Dutch legend says winning a UFC title would be the icing on the cake of his incredible career.

I have my own goals of course: UFC gold, Overeem said. To win the title would be a great close on my career.

Do you think Alistair Overeem will come out on top in Washington D.C.?

This article first appeared onBJPENN.comon 11/29/2019.

Continued here:
Alistair Overeem discusses the keys to his longevity - BJPenn.com

A Research Scientist with Agriculture and Agri-Food Canada says, by extending the longevity of sows in the breeding herd, pork producers can take greater advantage of their increased milk production in later parities.

Mothers milk is the only source of nutrients and energy available to the piglet at birth but, over the years, as the result of increased liter sizes, the amount of milk available to each piglet has decreased.

Improving Sow Lactational Performance was among the topics discussed in Saskatoon as part of Saskatchewan Pork Industry Symposium 2019.

Dr. Chantal Farmer, a Research Scientist in Sow Lactation Biology with Agriculture and Agri-Food Canada in Sherbrooke, says the amount of milk a sow will produce will increase in later parities.

The multiparous animal, so parity two and onward will produce 25 percent more milk than primiparous animals and the maximum amount of milk yield is in parities two to four. So really we should keep our sows up till four parities if we want to maximize the milk yield of the sows but, I know in Quebec anyway and Im quite sure its the same here, we dont keep sows for that long.

We have culling problems and longevity problems so thats something we need to work on because keeping the sows in the herd for four parties would maximize the milking capacity of those sows. The peak in milk yield is in parties two to four so what its telling us is that we need to keep our animals in the herd long enough to be able to take advantage of that peak in milk yields. So any management procedure you can have to make sure you extend longevity of these animals, avoid leg problems and anything you can do to have a good body condition, make sure theyre not too thin, its a good thing to keep these animals for the fourth first lactations.

~ Dr. Chantal Farmer, Agriculture and Agri-Food Canada

Dr. Farmer says the more milk the piglet consumes the faster it will grow and the less time it will take to reach market weight and the more colostrum, the piglet receives the more resistant it will be to disease.

More:
Increasing longevity allows maximized sow milk production - mySteinbach.ca

Shekhar Iyer

The Common Minimum Programme (CMP) that supposedly lists out key priorities for the new government opened with a preamble emphasising on secularism rather than propounding a grand political vision for Maharashtra.

Ironically, the Congress spent too much time hammering out the CMP until the early morning shock and awe type of swearing-in of Bharatiya Janata Partys (BJPs) Devendra Fadnavis as chief minister on November 23. This robbed the Opposition of its slumber and forced it to knock on the doors of the Supreme Court, whose intervention for an early floor test saved the alliance.

Soon, strategy managers were busy in herding their numbers and wooing the rebel, NCPs Ajith Pawar who was sworn-in as deputy chief minister under Fadnavis, back to the fold. The political drama ended on November 26, a day before the apex court-ordered floor test was to be conducted. This has left the numbers versus longevity game to be settled for another day.

For grabbing an opportunity of heading the government after 20 years, the Shiv Sena dumped a 30-year-old alliance with the BJP and shed initial disagreements on using the word secular in CMP, where now the word appears twice in the first paragraph itself. Reports were that the Sena was against the word appearing in the coalitions or Maha Vikas Aghadis CMP.

A day after he won the confidence vote, Shiv Sena chief and Maharashtras Chief Minister Uddhav Thackeray could not help saying that the Hindutva ideology is indispensable to the Shiv Sena and the party will not leave it. I am still with the ideology of 'Hindutva' and won't ever leave it," he said in the state assembly.

They rely on his averments that he would not allow anything that makes the common man feel terrorised. Therefore, the CMP would serve as a tool that will bridge the ideological and temperamental gulf between the Congress and the Sena by focusing on some pressing issues faced by the commoners, particularly farmers.

Other key focus areas in the CMP were hardly contentions issues as most parties agreed on tackling them on a priority basis: farm distress, unemployment, health, industry, social justice, women, education and urban development. Similarly, a law to ensure 80 per cent reservation in jobs for local/domicile youth (which is seen as the Senas plank) should not bother the ruling partners in terms of their ideologies.

However, observers feel that the sore-spot for the alliance is not in the new-found Shiv Sena-Congress relationship it is the equations within NCP leader Sharad Pawars family where his prodigy Ajit Pawar has returned to the NCP fold and where tension is brewing. It is said that the junior Pawar has still not reconciled to Thackeray being allowed a full five-year term as CM.

On the other side, the Congress is wary of Ajit Pawar after he joined hands with the BJP. That said, Congress interim President Sonia Gandhi and her aides realise that he is too important for the NCP and cannot be stopped from becoming deputy chief minister. Without him in the government, the NCP may well disintegrate.

Importantly, the Congress decision to nominate a former BJP MP Nana Patole for the assembly Speakers post is not exactly an expression of friendship towards the NCP. Patole, a fourth-term MLA from Sakoli, won Bhandara Lok Sabha seat as a BJP candidate, defeating former Union minister Praful Patel in 2014. Patole quit the BJP and joined the Congress following his disappointment with the top BJP leaders, citing their friendship with Patel and for refusing to act against his acts of commission and omission during the UPA regime. Patel remains a very influential leader in the NCP as he is close of the Pawars. Patel has never been averse to the NCP doing business with the BJP and wont take kindly to the Congress decision on Patole.

Be as it may, the Thackeray-led Cabinet will be expanded this week. The buzz is that, besides the post of deputy CM, the NCP is all set to emerge as the biggest gainer by getting high-profile portfolios such as revenue, home and the public works department. It is also likely that the NCP may get one more ministry than the Shiv Sena. Given these complexities, the BJPs wait may be longer than it thinks, but are there enough reasons for the Aghadi to come unstuck a year from now?

See the rest here:
Maha Vikas Aghadi | With numbers on its side, longevity is the challenge - Moneycontrol.com

The global longevity and anti-senescence therapies market should grow from $329.8 million in 2018 to $644.4 million by 2023 with a compound annual growth rate (CAGR) of 14.3% during 2018-2023.

Report Scope:

The scope of this report is broad and covers various therapies currently under trials in the global longevity and anti-senescence therapy market. The market estimation has been performed with consideration for revenue generation in the forecast years 2018-2023 after the expected availability of products in the market by 2023. The global longevity and anti-senescence therapy market has been segmented by the following therapies: Senolytic drug therapy, Gene therapy, Immunotherapy and Other therapies which includes stem cell-based therapies, etc.

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Revenue forecasts from 2028 to 2023 are given for each therapy and application, with estimated values derived from the expected revenue generation in the first year of launch.

The report also includes a discussion of the major players performing research or the potential players across each regional longevity and anti-senescence therapy market. Further, it explains the major drivers and regional dynamics of the global longevity and anti-senescence therapy market and current trends within the industry.

The report concludes with a special focus on the vendor landscape and includes detailed profiles of the major vendors and potential entrants in the global longevity and anti-senescence therapy market.

Report Includes:

71 data tables and 40 additional tables An overview of the global longevity and anti-senescence therapy market Analyses of global market trends, with data from 2017 and 2018, and projections of compound annual growth rates (CAGRs) through 2023 Country specific data and analysis for the United States, Canada, Japan, China, India, U.K., France, Germany, Spain, Australia, Middle East and Africa Detailed description of various anti-senescence therapies, such as senolytic drug therapy, gene therapy, immunotherapy and other stem cell therapies, and their influence in slowing down aging or reverse aging process Coverage of various therapeutic drugs, devices and technologies and information on compounds used for the development of anti-ageing therapeutics A look at the clinical trials and expected launch of anti-senescence products Detailed profiles of the market leading companies and potential entrants in the global longevity and anti-senescence therapy market, including AgeX Therapeutics, CohBar Inc., PowerVision Inc., T.A. Sciences and Unity Biotechnology

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Summary

Global longevity and anti-senescence therapy market deals in the adoption of different therapies and treatment options used to extend human longevity and lifespan. Human longevity is typically used to describe the length of an individuals lifetime and is sometimes used as a synonym for life expectancy in the demography. Anti-senescence is the process by which cells stop dividing irreversibly and enter a stage of permanent growth arrest, eliminating cell death. Anti-senescence therapy is used in the treatment of senescence induced through unrepaired DNA damage or other cellular stresses.

Global longevity and anti-senescence market will witness rapid growth over the forecast period (2018-2023) owing to an increasing emphasis on Stem Cell Research and an increasing demand for cell-based assays in research and development.

An increasing geriatric population across the globe and a rising awareness of antiaging products among generation Y and later generations are the major factors expected to promote the growth of global longevity and anti-senescence market. Factors such as a surging level of disposable income and increasing advancements in anti-senescence technologies are also providing traction to the global longevity and anti-senescence market growth over the forecast period (2018-2023).

According to the National Institutes of Health (NIH), the total geriatric population across the globe in 2016 was over REDACTED. By 2022, the global geriatric population (65 years and above) is anticipated to reach over REDACTED. An increasing geriatric population across the globe will generate huge growth prospectus to the market.

Senolytics, placenta stem cells and blood transfusions are some of the hot technologies picking up pace in the longevity and anti-anti-senescence market. Companies and start-ups across the globe such as Unity Biotechnology, Human Longevity Inc., Calico Life Sciences, Acorda Therapeutics, etc. are working extensively in this field for the extension of human longevity by focusing on study of genomics, microbiome, bioinformatics and stem cell therapies, etc. These factors are poised to drive market growth over the forecast period.

Global longevity and anti-senescence market is projected to rise at a CAGR of REDACTED during the forecast period of 2018 through 2023. In 2023, total revenues are expected to reach REDACTED, registering REDACTED in growth from REDACTED in 2018.

The report provides analysis based on each market segment including therapies and application. The therapies segment is further sub-segmented into Senolytic drug therapy, Gene therapy, Immunotherapy and Others. Senolytic drug therapy held the largest market revenue share of REDACTED in 2017. By 2023, total revenue from senolytic drug therapy is expected to reach REDACTED. Gene therapy segment is estimated to rise at the highest CAGR of REDACTED till 2023. The fastest growth of the gene therapy segment is due to the Large investments in genomics. For Instance; The National Human Genome Research Institute (U.S.) had a budget grant of REDACTED for REDACTED research projects in 2015, thus increasing funding to REDACTED for approximately REDACTED projects in 2016.

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Read more:
Longevity And Anti-Senescence Therap Market Analysis 2023 Leading Manufacturers & Regions, Application & Types - Guru Online News