Shortly after a baby’s first wail at birth she or he receives a tiny prick on the heel. A few drops of blood are caught on special filter paper to screen for myriad diseases. [More]
-- Read more on ScientificAmerican.com
http://rss.sciam.com/~r/sciam/topic/gene-therapy/~3/qJICV6zfIAo/article.cfm
Shortly after a baby’s first wail at birth she or he receives a tiny prick on the heel. A few drops of blood are caught on special filter paper to screen for myriad diseases. [More]
-- Read more on ScientificAmerican.com
http://rss.sciam.com/~r/sciam/topic/gene-therapy/~3/qJICV6zfIAo/article.cfm
Four researchers from UCLA’s Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have received Early Translational Research Awards totaling approximately $13 million from the California Institute for Regenerative Medicine, the state's stem cell agency. The UCLA researchers received four of the 12 total awards; no other institution received more than one.
The Independent Citizens Oversight Committee, CIRM’s governing body, announced at its Aug. 28 meeting in La Jolla, Calif., that grant recipients included Dr. Jerome Zack, professor of medicine and microbiology, immunology and molecular genetics; Dr. Robert Reiter, Bing Professor of Urologic Research; Dr. Donald Kohn, professor of pediatrics and microbiology, immunology and molecular genetics in th...
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Earlier this year Yaniv Erlich of the Whitehead Institute for Biomedical Research at M.I.T. sent bioethicists into a frenzy when he and his team uncovered the names of people whose anonymous genome...
-- Read more on ScientificAmerican.com
http://rss.sciam.com/~r/sciam/topic/gene-therapy/~3/c3dvzwuFAUI/article.cfm
Earlier this year Yaniv Erlich of the Whitehead Institute for Biomedical Research at M.I.T. sent bioethicists into a frenzy when he and his team uncovered the names of people whose anonymous genome...
-- Read more on ScientificAmerican.com
http://rss.sciam.com/~r/sciam/topic/gene-therapy/~3/c3dvzwuFAUI/article.cfm
Stem Cell and Gene Therapy for CV Disease: Lessons learned and future directions
Les Miller, MD Director of the USF Heart Institute Professor of Cardiovascular Sciences at the USF Health Morsani College of Medicine Cardiology Grand Rounds...
By: DukeClinicalResearch
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Stem Cell and Gene Therapy for CV Disease: Lessons learned and future directions - Video
Macular Degeneration And Acupuncture: Gene Therapy and Stem Cell for AMD Safe?
http://www.MacularDegenerationSupport.com or (908) 264-5484 Download the FULL webinar for free by clicking the link. Dr. Andy Rosenfarb conducted an hour lon...
By: Dr. Andy Rosenfarb
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Macular Degeneration And Acupuncture: Gene Therapy and Stem Cell for AMD Safe? - Video
Abstract
Few options are available for treating patients with advanced prostate cancer (PC). As PC is a slow growing disease and accessible by ultrasound, gene therapy could provide a viable option for this neoplasm. Conditionally replication?competent adenoviruses (CRCAs) represent potentially useful reagents for treating prostate cancer (PC). We previously constructed a CRCA, Cancer Terminator Virus (CTV), which showed efficacy both in vitro and in vivo for PC. The CTV was generated on a serotype 5?background (Ad.5?CTV) with infectivity depending on Coxsackie?Adenovirus Receptors (CARs). CARs are frequently reduced in many tumor types, including PCs thereby limiting effective Ad?mediated therapy. Using serotype chimerism, a novel CTV (Ad.5/3?CTV) was created by replacing the ...
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'Grinder' can listen to music player by wearing a loose wire coil around his neckDon't offer Rich Lee a pair of headphones to listen to music: he's already got a pair, even though you can't see them. They're implanted in his ears – a procedure carried out by a "body modification" expert.Now, by connecting his music player to a loose wire coil around his neck (which he can tuck under his shirt), Lee can listen to music without blocking out the outside world. The tiny magnets implanted invisibly in his outer ears pick up the signal and generate sound.But that's only the beginning. Lee, 34, who works as a salesman, intends to hook it up to an ultrasonic rangefinder – effectively giving himself bat-like echolocation. And he would like to have X-ray vision, super-strength, and anything else...
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'Grinder' can listen to music player by wearing a loose wire coil around his neckDon't offer Rich Lee a pair of headphones to listen to music: he's already got a pair, even though you can't see them. They're implanted in his ears – a procedure carried out by a "body modification" expert.Now, by connecting his music player to a loose wire coil around his neck (which he can tuck under his shirt), Lee can listen to music without blocking out the outside world. The tiny magnets implanted invisibly in his outer ears pick up the signal and generate sound.But that's only the beginning. Lee, 34, who works as a salesman, intends to hook it up to an ultrasonic rangefinder – effectively giving himself bat-like echolocation. And he would like to have X-ray vision, super-strength, and anything else...
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When Google CEO Larry Page blogged about his struggles speaking and, at times, breathing last week on his Google+ page he spotlighted a rare condition, bilateral vocal cord paralysis , which leaves sufferers short of breath and with few viable treatment options. This is likely to change in coming years. Page has deep pockets and has promised to fund research into the disorder via the Voice Health Institute . In the meantime scientists are experimenting with electrical stimulation technologies to enhance existing voice therapy as well as surgical treatments. [More]
Source:
http://rss.sciam.com/click.phdo?i=b3c657c36bd85f3126649923bb8701fe
When Google CEO Larry Page blogged about his struggles speaking and, at times, breathing last week on his Google+ page he spotlighted a rare condition, bilateral vocal cord paralysis , which leaves sufferers short of breath and with few viable treatment options. This is likely to change in coming years. Page has deep pockets and has promised to fund research into the disorder via the Voice Health Institute . In the meantime scientists are experimenting with electrical stimulation technologies to enhance existing voice therapy as well as surgical treatments. [More]
Source:
http://rss.sciam.com/click.phdo?i=b3c657c36bd85f3126649923bb8701fe
Authors: Yoshida T, Kondoh M, Mizuguchi H, Yagi K
Abstract
Hepatitis C virus (HCV) is a hepatotropic member of the Flaviviridae family and contains a 9.6 kb positive-sense RNA genome. Approximately 170-million people are infected with HCV worldwide. These people face increased risks of chronic hepatitis, cirrhosis and hepatocellular carcinoma compared with the general population. Transduction of the HCV genome into hepatocytes is essential for understanding the mode of action of HCV infection, and for preparing HCV, evaluating HCV replication, and screening anti-HCV drugs. Although electroporation of in vitro-synthesized HCV genome and transduction of plasmid vectors containing the HCV genome are widely used in HCV research, a more convenient system with higher transduction efficie...
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Authors: Yoshida T, Kondoh M, Mizuguchi H, Yagi K
Abstract
Hepatitis C virus (HCV) is a hepatotropic member of the Flaviviridae family and contains a 9.6 kb positive-sense RNA genome. Approximately 170-million people are infected with HCV worldwide. These people face increased risks of chronic hepatitis, cirrhosis and hepatocellular carcinoma compared with the general population. Transduction of the HCV genome into hepatocytes is essential for understanding the mode of action of HCV infection, and for preparing HCV, evaluating HCV replication, and screening anti-HCV drugs. Although electroporation of in vitro-synthesized HCV genome and transduction of plasmid vectors containing the HCV genome are widely used in HCV research, a more convenient system with higher transduction efficie...
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Bone Marrow Stem Cell Transplantation and Gene Therapy for Cystinosis
A presentation by Stephanie Cherqui, PhD, University of California, San Diego at the 2013 Day of Hope Cystinosis Research Foundation Family Conference, Balbo...
By: Natalieswish
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Bone Marrow Stem Cell Transplantation and Gene Therapy for Cystinosis - Video
A child born to an HIV-infected mother in Mississippi may be cured after a swiftly administered course of drugs. A number of factors make the child’s case unique, however, and clinicians caution that we have not discovered a general cure for HIV yet. Still, the medical first may hint at ways to fight the AIDS-causing virus .
Source:
http://rss.sciam.com/click.phdo?i=95337d9798ea17db628f12536ca0a05b
Editor’s Note: Excerpted from Shouting Won’t Help: Why I--and 50 Million Other Americans--Can’t Hear You , by Katherine Bouton, published by Sarah Crichton Books, an imprint of Farrar, Straus and Giroux, LLC. Copyright © 2013 Katherine Bouton. All rights reserved.
Source:
http://rss.sciam.com/click.phdo?i=26ba9d76b5b91ce8e95b09bea6e3b5c4
A child born to an HIV-infected mother in Mississippi may be cured after a swiftly administered course of drugs. A number of factors make the child’s case unique, however, and clinicians caution that we have not discovered a general cure for HIV yet. Still, the medical first may hint at ways to fight the AIDS-causing virus .
Source:
http://rss.sciam.com/click.phdo?i=95337d9798ea17db628f12536ca0a05b
Editor’s Note: Excerpted from Shouting Won’t Help: Why I--and 50 Million Other Americans--Can’t Hear You , by Katherine Bouton, published by Sarah Crichton Books, an imprint of Farrar, Straus and Giroux, LLC. Copyright © 2013 Katherine Bouton. All rights reserved.
Source:
http://rss.sciam.com/click.phdo?i=26ba9d76b5b91ce8e95b09bea6e3b5c4
Muscle stiffness is a major clinical feature in Duchenne muscular dystrophy (DMD). DMD is the most common lethal inherited muscle-wasting disease in boys, and it is caused by the lack of the dystrophin protein. We recently showed that the extensor digitorum longus (EDL) muscle of mdx mice (a DMD mouse model) exhibits disease-associated muscle stiffness. Truncated micro- and mini-dystrophins are the leading candidates for DMD gene therapy. Unfortunately, it has never been clear whether these truncated genes can mitigate muscle stiffness. To address this question, we examined the passive properties of the EDL muscle in transgenic mdx mice that expressed a representative mini- or micro-gene (H2-R15, R2-15/R18-23/C, or R4-23/C). The passive properties were measured at the ages of 6 and 20 mo a...
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