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'Dining with Diabetes' classes offered in Barryton

BARRYTON The Lions Club International and Michigan State University Extension are partnering to offer free "Dining with Diabetes" workshops in Barryton.

Thanks to the Lions Club International for giving back to this community. It is extra special to be able to bring 'Dining with Diabetes' to the small community of Barryton, MSUE educator Pam Daniels stated in a press release.

"Dining with Diabetes" lasts four weeks and includes research-based education, food preparation demonstrations and healthy recipe tasting. Participants receive a textbook and materials. The goals of the classes are for participants to learn self-management skills surrounding their health and to work closely with their healthcare providers.

"Dining with Diabetes" is for anyone with or at-risk of developing diabetes. Both diabetes self-care and cooking skills are taught each week. MSUE Chef Don Zimmer will be the featured guest chef each week.

Classes will take place from 1:30-3:30 p.m. Jan. 22 and 29, and Feb. 5 and 12, at the Barryton Senior Center, 71 E. Northern Ave.

RSVP is required. Call Lisa Baker at 231-592-0792 to sign up.

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'Dining with Diabetes' classes offered in Barryton - The Pioneer

Alyssa Vela, PhD; Health Psychology Fellow, McLaren FlintPhoutdavone Phimphasone-Brady, PhD; Postdoctoral Fellow, University of Colorado School of Medicine

If you have diabetes, you probably know all too well that eating is often the most challenging aspect of diabetes management. You are not alone if you struggle to figure out what to eat, when to eat, and how to eat, even years after a diabetes diagnosis. When it comes to eating and diabetes, there are a few key aspects to pay attention to. Some of these eating habits may be familiar to you, and they might even start to cause problems in your life, such as your blood sugar, your relationships with friends and family, or even your relationship with your doctor.

Be on the lookout for red flags that your eating habits may be problematic:

Everyone has to eat, so how we think about food and go about eating, plays a really important role in our happiness and well-being. There are many ways these patterns of eating can be improved to prevent any further eating-related problems and to help people meet their diabetes management goals. Such strategies include:

If your eating habits affect your life and ability to manage diabetes, talk to your doctor, a diabetes educator, and/or a mental health provider who specializes in helping patients with the challenges associated with diabetes management (a list can be found here).

Back to Healthy Living

More:
What You Should Know About Eating Behaviors and Diabetes | SBM - Society of Behavioral Medicine

Every time Jennifer Hunt crosses a finish line, her mother, her brother and her niece flash in her mind.

She runs for those three, she said, and all those diagnosed with Type 1 diabetes at an early age. Her mother died from diabetes-related complications when Hunt was 33.

Also known as juvenile diabetes, people can live for years with the disease but it is not an easy life. Hunts mother was diagnosed with Type 1 diabetes when she was 14; her brother at age 9; and her niece at age 6.

I lost my best friend and my rock. My brother is 55 and is in end-stage renal failure. My niece is my champion and is such an awesome young lady, said Hunt, 51. I run in remembrance of my mom, and I champion my niece as my reason to give her strength knowing someone understands her and what she is going through.

Through the Chevron Houston Marathon Run for a Reason Program, the Sugar Land resident is raising funds for the Juvenile Diabetes Research Fund. Last year, she raised about $5,000. This year, she is attempting to raise at least $2,500.

Since 1995, the marathon has hosted the charity program as way for race organizers to connect local philanthropies with the running community, raising more than $31 million since its inception.

On HoustonChronicle.com: Muffy King's journey started in the water. Now she creates Houston running events.

Two years ago, Hunt started running after she was diagnosed with leukemia at age 50. She needed an outlet to deal with the road ahead that was filled with doctors appointments and cancer treatment.

Hunts mother, Lucille B. Isdale, was an active volunteer for the JDRF, a nonprofit organization at the forefront of diabetes research. The foundation funds medical trials and studies that led to the first lab-engineered insulin decades ago. More recently, the foundation helped pay for studies related to an artificial pancreas device system, necessary for diabetics to regulate glucose.

This year, Hunt will auction a custom guitar by heavy metal guitarist Dan Fastuca, podium hats from Mazda race car driver Luke Oxner and a gift certificate to Sugar Land MMA. So far, she has raised $1,810.

I turned the worst time of my life into the most rewarding time by doing for others, Hunt said. I want to carry on my moms legacy and the work she did with JDRF. Every finish line I cross is such a victory on so many levels: fighting cancer and fighting for a cure for children (with diabetes) and families like mine.

Sundays half marathon will be Hunts fifth 13.1-mile race. She was aiming to race a full marathon this time, but two surgeries in July put her behind in training. She plans to train for the full marathon next year.

While working full-time, training and raising money for the foundation, Hunt is still fighting leukemia. Her next treatment will be two days after her race; she received her physicians permission to run.

You either become a victim or a victor, she said. I hope the example I set for my niece is no matter what is going on in life, go for being the victor.

This years Run for a Reason program kicked off Dec. 3 with a social media contest. As sponsor partner, Chevron donates $75,000, to be split between three charities: the charity that raises the most money; the one with the most votes; and the charity that receives the most donations from individual donors.

On HoustonChronicle.com: New mom's Houston Marathon goal isn't about pace -- it's leaving a legacy for her daughter

The winners will be announced Friday.

Every charity part of our program has local ties to Houston, said Muffy King, the marathons director of marketing, media and branding. The money is staying here, which resonates with our community.

Charity runners have to raise at least $350 to $500 to qualify for the race, but many raise thousands.

Kung Fu Running Club, already a mainstay with weekly recreational runs at Kung Fu Saloon, has coordinated Happy Hours to raise funds for its chosen charity. Many use social media, GoFundMe accounts and email campaigns, as well.

Its a cliche, but it takes a community for efforts like this. Whats great about our community is everyone is willing to help, King said.

There are 65 charities, 150 running teams and 1,160 fundraisers in this years program.

Currently, the top fundraiser so far is Lawrence Despain who has raised nearly $19,000 for the Snowdrop Foundation, Inc., an organization that provides college scholarships for pediatric cancer patients and childhood cancer survivors.

julie.garcia@chron.com

Twitter: @reporterjulie

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25 years, $31 million: How Houston running community has helped area charities - Houston Chronicle

More than 30 million Americans have diabetes. The vast majority suffer from Type 2 diabetes, which arises when the body doesnt process insulin properly. This causes blood sugar levels to rise and potentially triggers a host of other health problems, like heart disease, kidney disease and loss of vision. The disease has long been characterized as a chronic condition, requiring people to receive regular insulin injections, test their blood sugar levels and take medications.

However, a growing body of evidence suggests that reversing the condition essentially, bringing blood sugar back to a non-diabetic level without meds may be possible through diet and weight loss. In a 2016 study in Barbados, more than half of participants given a low-calorie, low-carb diet, in addition to fibrous fruits and vegetables, were able to reduce their blood sugar to non-diabetic levels. Weight-loss surgery has also been used as a technique to keep diabetes at bay.

But not everybody can control their blood sugar levels without medication, particularly in the diseases later stages. And experts caution that major lifestyle changes involving diet can be difficult for many people to maintain.

Often times, people will go on these very restrictive, low-calorie diets, says Ann Albright, director of the Division of Diabetes Translation at the Centers for Disease Control and Prevention. The evidence is clear that, for a majority of people, those are not sustainable.

Read more:

When Dieting, Should We Be Fasting or Grazing?

The Biggest Factor Behind Obesity May Be One We Don't Want to Hear

Breakfast Might Not Be So Essential After All

Visit link:
Can You Reverse Type 2 Diabetes with Diet and Weight Loss? - Discover Magazine

Lawton First Christian Church and the Oklahoma Healthy Aging Initiative (OHAI) Southwest Center of Healthy Aging are collaborating to provide the Powerful Tools for Caregivers and Diabetes and Beyond programs.

Both classes will be held at First Christian Church, 701 SW D, beginning the first week of January.

Powerful Tools for Caregivers is a class series designed to help family caregivers take better care of themselves while caring for a family member or friend. In the six weekly classes, caregivers will develop self-care tools to reduce stressors, change negative self-talk, communicate their needs to family members and healthcare or service providers, effectively communicate in challenging situations, deal with difficult feelings, and make tough caregiving decisions. Class participants will have access to a copy of The Caregiver Help Book, developed specifically for the training.

This class will begin at 2 p.m. Jan. 6 and will continue once a week through Feb. 17.

The Diabetes and Beyond Program is a six-week program designed to teach self-management tools to older adults and their caregivers who want to learn how to manage diabetes to improve their overall quality of life. This program is interactive and will teach through small groups, games, activities and support conversations. Lessons include learning about management through meal planning, how diabetes affects the body, how to monitor changes, tips on physical activity and encouraging family involvement.

The diabetes class will begin at 2 p.m. Jan. 8 and will continue once a week through Feb. 12.

Instructors are provided by OHAI, a program of the Donald W. Reynolds Department of Geriatric Medicine at the University of Oklahoma. OHAI serves all individuals who are eligible for its programs without regard to race, national origin, ancestry, color, religion, sex, age or disability, under program guidelines.

To receive additional information or to reserve a spot in the classes, call OHAIs Southwest Center of Healthy Aging at (580) 699-3976.

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Powerful tools for caregivers, diabetes classes on the way - The Lawton Constitution

The significant findings of the DAPA-HF data have been well received in both the scientific and payer communities, but we also need to ensure that patients with diabetes are educated on the signs, symptoms, and risk factors linked with heart failure, said Kiersten Combs, BS, US vice president of Cardiovascular Metabolism at AstraZeneca.

The significant findings of the DAPA-HF data have been well received in both the scientific and payer communities, but we also need to ensure that patients with diabetes are educated on the signs, symptoms, and risk factors linked with heart failure, said Kiersten Combs, BS, US vice president of Cardiovascular Metabolism at AstraZeneca.

Transcript

Can you discuss the importance of the patient-reported outcomes data that was presented at AHA 2019? How do these data contribute to value-based agreements?

Especially in the heart failure patients where these patients are highly symptomatic, the data that we're reporting out, specifically using the Kansas City Cardiomyopathy Questionnaire [KCCQ] score, demonstrates that when patients take FARXIGA, they will actually feel better. So, not only is there an important clinical benefit, but there's also important patient benefit. I believe that will translate into the discussions in the impact that it will have with payers because they're ultimately looking to not only provide better health solutions for their patients, but also lower the cost to serve those patients.

Were hearing more about value-based agreements in the diabetes and cardiovascular area, including agreements directly between manufacturers and large employers or purchasing groups that represent employers. Can you discuss any novel solutions that AstraZeneca is pursuing in this area?

We are extremely proud that we have been thought leaders in this space, not only with the number of value-based agreements we have with payers today, but also that we have these agreements across the breadth of our portfolioso within the cardiovascular metabolic portfolio, but really also across our respiratory and oncology portfolio too. So, when we look at the data, such as what's being presented here, as well as everything else in our portfolio, we are engaging payers across the portfolio seeing what is possible; but I would just add that while the DAPA-HF data has been significant, and well received in the scientific community and in the payer community, I would also say that's not enough. We also need to make sure that we're educating patients on the signs, symptoms, and risk factors associated with heart failure. So, we're also quite proud that we've made an investment in just launching here at AHA 2019, a public service campaign called Diabetes Can Break Your Heart that will do exactly that.

Originally posted here:
Kiersten Combs: Educating Patients With Diabetes on Heart Failure Risk Is Key to Effective Care - AJMC.com Managed Markets Network

Abbas Ebadi,1,2 Davide Ausili,3 Ahmed N Albatineh,4 Shahin Salarvand,5 Reza Ghanei Ghashlagh6

1Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran; 2Nursing Faculty, Baqiyatallah University of Medical Sciences, Tehran, Iran; 3Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy; 4Department of Community Medicine and Behavioral Sciences, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait; 5Social Determinant of Health Research Center, School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran; 6Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran

Correspondence: Reza Ghanei GhashlaghSocial Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Pasdaran Ave, Sanandaj 6618634683, IranTel +98 9144050284Fax +98 36237511Email Rezaghanei30@yahoo.com

Background: Lifelong self-care is important in particular for patients with diabetes, because preventing diabetes complications can help maintain the quality of life and independence of diabetic patients. Currently, there are 16 self-care tools, the majority of which focus on one part of self-care. Therefore, the aim of this study was to evaluate the psychometric properties of the Farsi Self-Care of Diabetes Inventory (F-SCODI) in Iran.Methods: A cross-sectional study was performed on 400 diabetic patients who were selected by convenience sampling to complete the F-SCODI. In this regard, construct validity was assessed using exploratory factor analysis. Additionally, the internal consistency of the F-SCODI was evaluated by McDonalds omega coefficient and Cronbachs alpha; whereas its stability was assessed by a test re-test approach.Results: In total, four factors were extracted (activity-nutritional behavior, smoking avoidance behavior, illness-related behaviors, and health-promoting behaviors) in the dimension of self-care maintenance, three factors (symptom monitoring, symptom assessment, and symptom recognition) in the dimension of self-care monitoring, two factors (autonomous self-care and consultative self-care) in the self-care management dimension, and two factors (task-specific self-care confidence and persistence self-care) in the dimension of confidence. In this regard, the overall consistencies of the four dimensions were 0.809, 0.767, 0.590, and 0.886, respectively.Conclusion: This study indicated that the Farsi version of SCODI had acceptable internal consistency and reliability as well as content and construct validity. Given the acceptable psychometric properties, this tool can be used in future studies in Iranian patients with diabetes.

Keywords: diabetes, self-care, Self-Care of Diabetes Inventory, factor analysis, Iran

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Psychometric Evaluation of the Farsi Version of the Self-Care of Diabe | DMSO - Dove Medical Press

Mon, Dec 30, 2019 - 5:50 AM

Singapore

DIABETES is one of the fastest growing health challenges of the 21st century. In Singapore, the prevalence of diabetes in adults aged 18 and above has nearly doubled in just 15 years - from 7 per cent in 2004 to 13.7 per cent today (about 606,000 people).

What is perhaps of most concern about the diabetes trend is how unaware people remain of it.

"Diabetes is a silent disease," explained Pedro Goncalves, head of Roche Diabetes Care Region International (APAC, Middle-East, Africa, Russia & LATAM). "You can have it and not know it until it's quite late."

The International Diabetes Federation (IDF) estimates that half of adults with diabetes - about 232 million people worldwide - are undiagnosed, which puts them at high risk of developing serious diabetes-related complications such as blindness, nerve damage, heart disease and limb amputation. Singapore, for example, has the world's highest rate of diabetic kidney failure, despite its proclaimed war on diabetes.

Therefore, companies such as Roche Diabetes Care have begun investing in digital alternatives to help people track their health information.

"It's very important to have information on glucose levels and other markers immediately accessible by doctors and healthcare professionals," said Mr Goncalves. Digital technology that can facilitate quicker, easier consolidation of such information will help diabetes patients get better at staying within healthy ranges, he added.

The advent of digital technology is timely as the cost of diabetes treatment is increasing at double-digit rates throughout Asia. In Singapore alone, over S$1 billion is spent each year on managing diabetes.

Rising trends skew disproportionately towards Type 2 diabetes, driven by growing urbanisation and changing lifestyle habits (higher calorie intake, increasing consumption of processed foods, sedentary lifestyles), said Mr Goncalves. This makes diabetes difficult to detect and manage without regular visits to the doctor.

"It's not about providing only clinical decisions like prescribing, it's really about helping them understand what they do, what they eat, how to balance their lifestyle so they can control the disease better," he said.

Compared to traditional methods, digital technology is able to facilitate not only reactive treatment but also proactive prevention, which many healthcare professionals agree is both more effective and less costly for disease management.

"It's about preventive action and the need to work on the early stage of diabetes, so we avoid this epidemic that is taking place in Asia more than anywhere else in the world," said Mr Goncalves.

One such digital solution is mySugr, a free mobile app for managing diabetes that collects and consolidates relevant therapy data in one place through external devices, integrations, and manual entry. Since its June launch in Singapore, the app has garnered nearly 9,000 users.

"The data allows us to zero in on the areas we can improve on, be it adjusting medicine dosage or food intake, so that I can live as normally as I can," said mySugr user Shane Sim, 31. "It is definitely better than the old school way of using a pen and paper logbook, which is very inconvenient to carry around."

Making diabetes "suck less", as the app's tagline claims, is a helpful motivator for diabetes patients who struggle daily with having to keep track of meals, medications, blood sugar levels and other important data. Said Heng Pei Yan, 33: "I appreciate the constant improvements and modifications made to the app to make blood sugar monitoring fun for users."

"It's a very user-friendly interface," said Eileen Lee, head of communications at Roche Diabetes Care. "It's very gamified, it's very easy to enter your data, so it's not complicated, even for older users."

With the burden of disease management lightened and streamlined by digital solutions, better outcomes can be expected, said Mr Goncalves.

"Patients only see a doctor once per year or twice. It's impossible to manage a disease that is influenced by behaviour if you don't have permanent support," he explained. "We need to find other ways of providing support to people, and that's exactly where digital solutions come in."

For S$210, mySugr also offers a three-month subscription plan for mySugr Coaching, an in-app add-on bundle of special features that includes access to direct communication with diabetes educators for personalised advice between clinic visits.

The growing capabilities of healthcare technology aside, the responsibility to take action remains key to health and disease management.

"Technology is just the bridge to help you do things right," said Mr Goncalves. "But it takes a while for humans to change their behaviour ... and that's always a challenge."

Original post:
The war on diabetes goes digital - The Business Times

Poxel and its new diabetes tablet are heading to regulators. Well, in Japan at least.

The French pharma and its Japanese partner Sumitomo Dainippon announced the third straight Phase III success for its new kind of diabetes tablet. In the year-long, open-label TIMES 2 trial, Imeglimin decreased blood sugar levels (HbA1c) as a monotherapy or in combination with one of any of 8 common diabetes drugs. That included a .92% decline when given with DDP-4 inhibitors, one of the most common diabetes meds in Japan.

The results keep Poxelon track for the same 2020 Japanese regulatory submission and 2021 approval they laid out after positive double-blind TIMES 1 results were announced in April. Top-line TIMES 3 results, also positive, were unveiled in November.

The results sent Poxels stock on the European exchange up 9.92% to 9.75 per share.

The TIMES 2 results represent a significant milestone for Imeglimin, with the completion of our robust Phase 3 program in Japan, Poxel CEO Thomas Kuhn said in a statement referring to all three trials. Taken together, these results feature Imeglimins potential to treat type 2 diabetes at multiple stages of the disease.

Poxels path to the rest of the world remains less clear. Nearly two years ago, the French group sold US and European rights to Vivek Ramaswamys Roivant in a deal worth $50 million upfront and up to $600 million in milestones. The deal had been long-sought; although Poxel had a positive Phase IIb in 2014 and dosing levels to go to Phase III, they needed a deeper-pocketed partner willing to take on the heavy financial burden of a global diabetes trial.

Updates, though, have been sparse since they signed that deal in February 2018. The Poxel website still lays out the 2018 plans under the Imeglimin US/EU tab, and the Roivant website refers back to the Poxel one. Clinicaltrials.gov lists only one active trial for the drug a Phase I in Munich for hepatic impaired subjects.

The compound, though, will enter the Japanese regulatory process with a bevy of evidence behind it. Part of a new class of oral chemical agents called glimins, the drug is designed to target all three key organs affected in Type II diabetes: Increasing insulin in the pancreas in a glucose-dependent manner, decreasing excess glucose production in the liver and enhancing insulin sensitivity in muscles.

Collectively, the three trials enrolled 1,100 patients. TIMES 2 was open-label but TIMES 1 and 3 were double-blind. All met primary endpoints.

Poxel should find a ready market, too. An aging population and rising obesity have swelled the number of suspected diabetics in Japan past 10 million as of 2016, according to past estimates from Nikkei.

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Poxel passes 3rd straight Phase III diabetes trial in Japan, but what's going on with US/EU partner Roivant? - Endpoints News

New Delhi [India], Dec 29 (ANI): Nearly 400 people with known diabetes (type-1) below the age of 30 years underwent the comprehensive annual screening for their complication due to their health condition at the annual medical camp- 'Diabetes Onset on Youth' organised with the All India Institute of Medical Sciences (AIIMS) on Saturday.

The participants included children, teenagers, and young adults till 30 years of age from Delhi-NCR for the annual screening process which is a mandatory part of their clinical practices.

Patients were from AIIMS endocrinology department, paediatrics (AIIMS) and Safdarjung Hospital.

"The idea for these camp is that all people with diabetes need to undergo a periodic evaluation and annual evaluation which is more detailed and also includes screening for complications associated with diabetes," (Prof) Dr Nikhil Tandon, head of endocrinology and metabolism department at AIIMS told ANI.

In 2006, ICMR constituted a Registry of People with Diabetes with Young Age at Onset (YDR), to maintain a data- Youth Onset of Diabetes.

"The effort is to try and make it easier for these individuals who already have diabetes. This medical camp at AIIMS is a single-window, single day system and all that patients require for investigation was taken care," Dr Tandon said.

Experts say that Type -1 diabetes occurs usually in the first two decades of life when body's immune system destroys the cell in the pancreas which generates insulin, as a result, these young people do not have insulin production inside their body. So they are compelled to take insulin from outside and dependent on insulin for most of their survival.

On the other hand, Type 2 diabetes occurs mostly in the older age group population. Under this health complication, the initial part of the disease is associated with a condition called- insulin resistance diabetes, though the body produces insulin the body's tissue remains insensitive towards action. Therefore, doctors need to give more & more insulin and hence a lot of time, we need to give medications by mouth is also enough to take care of the process.

In 2014, AIIMS started the annual evaluation of people with known diabetes wherein 200 participants got registered and underwent annual health check for the complications associated with the disease. The project is funded by ICMR.

Investigations like haemoglobin A1c, proteinuria or microalbuminuria in urine, cholesterol, and fats in the blood (lipid profile) and kidney function test were performed on participants.

Citing the latest data published in the International Diabetes Federation (IDF), Dr Tandan said that currently, India has a burden of 100,000 people suffering from known diabetes.

Patients and attendants were sensitised through nukkad nataks, poster making, and quiz competitions. (ANI)

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AIIMS conducts annual screening of about 400 people with Type-1 diabetes - Yahoo India News

What are the chronic complications of diabetes?

These diabetes complications are related to blood vessel diseases and are generally classified into small vessel disease, such as those involving the eyes, kidneys and nerves (microvascular disease), and large vessel disease involving the heart and blood vessels (macrovascular disease). Diabetes accelerates hardening of the arteries (atherosclerosis) of the larger blood vessels, leading to coronary heart disease (angina or heart attack), strokes, and pain in the lower extremities because of lack of blood supply (claudication).

The major eye complication of diabetes is called diabetic retinopathy. Diabetic retinopathy occurs in patients who have had diabetes for at least five years. Diseased small blood vessels in the back of the eye cause the leakage of protein and blood in the retina. Disease in these blood vessels also causes the formation of small aneurysms (microaneurysms), and new but brittle blood vessels (neovascularization). Spontaneous bleeding from the new and brittle blood vessels can lead to retinal scarring and retinal detachment, thus impairing vision.

To treat diabetic retinopathy, a laser is used to destroy and prevent the recurrence of the development of these small aneurysms and brittle blood vessels. Approximately 50% of patients with diabetes will develop some degree of diabetic retinopathy after 10 years of diabetes, and 80% retinopathy after 15 years of the disease. Poor control of blood sugar and blood pressure further aggravates eye disease in diabetes.

Cataracts and glaucoma are also more common among diabetics. It is also important to note that since the lens of the eye lets water through, if blood sugar concentrations vary a lot, the lens of the eye will shrink and swell with fluid accordingly. As a result, blurry vision is very common in poorly controlled diabetes. Patients are usually discouraged from getting a new eyeglass prescription until their blood sugar is controlled. This allows for a more accurate assessment of what kind of glasses prescription is required.

Kidney damage from diabetes is called diabetic nephropathy. The onset of kidney disease and its progression is extremely variable. Initially, diseased small blood vessels in the kidneys cause the leakage of protein in the urine. Later on, the kidneys lose their ability to cleanse and filter blood. The accumulation of toxic waste products in the blood leads to the need for dialysis. Dialysis involves using a machine that serves the function of the kidney by filtering and cleaning the blood. In patients who do not want to undergo chronic dialysis, kidney transplantation can be considered.

The progression of nephropathy in patients can be significantly slowed by controlling high blood pressure, and by aggressively treating high blood sugar levels. Angiotensin converting enzyme inhibitors (ACE inhibitors) or angiotensin receptor blockers (ARBs) used in treating high blood pressure may also benefit kidney disease in patients with diabetes.

Nerve damage from diabetes is called diabetic neuropathy and is also caused by disease of small blood vessels. In essence, the blood flow to the nerves is limited, leaving the nerves without blood flow, and they get damaged or die as a result (a term known as ischemia). Symptoms of diabetic nerve damage include numbness, burning, and aching of the feet and lower extremities. When the nerve disease causes a complete loss of sensation in the feet, patients may not be aware of injuries to the feet, and fail to properly protect them. Shoes or other protection should be worn as much as possible. Seemingly minor skin injuries should be attended to promptly to avoid serious infections. Because of poor blood circulation, diabetic foot injuries may not heal. Sometimes, minor foot injuries can lead to serious infection, ulcers, and even gangrene, necessitating surgical amputation of toes, feet, and other infected parts.

Diabetic nerve damage can affect the nerves that are important for penile erection, causing erectile dysfunction (ED, impotence). Erectile dysfunction can also be caused by poor blood flow to the penis from diabetic blood vessel disease.

Diabetic neuropathy can also affect nerves to the stomach and intestines, causing nausea, weight loss, diarrhea, and other symptoms of gastroparesis (delayed emptying of food contents from the stomach into the intestines, due to ineffective contraction of the stomach muscles).

The pain of diabetic nerve damage may respond to traditional treatments with certain medications such as gabapentin (Neurontin), phenytoin (Dilantin), and carbamazepine (Tegretol) that are traditionally used in the treatment of seizure disorders. Amitriptyline (Elavil, Endep) and desipramine (Norpraminine) are medications that are traditionally used for depression. While many of these medications are not indicated specifically for the treatment of diabetes related nerve pain, they are used by physicians commonly.

The pain of diabetic nerve damage may also improve with better blood sugar control, though unfortunately blood glucose control and the course of neuropathy do not always go hand in hand. Newer medications for nerve pain include Pregabalin (Lyrica) and duloxetine (Cymbalta).

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9 Symptoms of Type 1 & Type 2 Diabetes: Complications ...

Diabetes is a condition where your body either does not produce enough insulin or it is unable to use the insulin that it produces effectively. Insulin is a hormone that regulate your blood sugar levels. Uncontrolled diabetes can lead to many chronic health problems that can, at times, be fatal. The World Health Organisation says that diabetes can be treated, and its consequences avoided or delayed with diet, physical activity, medication and regular screening and treatment for complications.

Here, we reveal the best diabetes tips to follow in 2020. With our tips, you can save your self from a lot of adverse complications and live a long and healthy life.

If you are overweight, try to come down to your ideal body weight. Maintaining your body weight will help you to keep your blood sugar levels under control. If you think it will help, consult a nutritionist or your doctor. Hey will be able to guide you on the right path.

Add a lot of fruits and vegetables to your diet. Have fibre rich foods and avoid processed and sugary foods. Eat whole grains and legumes. Keep away from alcohol and stop smoking. All this will boost your overall health and also help you to keep your diabetes in check.

This test will help you know your average blood sugar level for the past 2 to 3 months. This will go a long way in helping you to formulate a plan to check your sugar levels. Seek an appointment with your doctor and get this test done. You should ideally do this twice a year. It will help you know if you are on the right track.

Heart diseases is a common complication of diabetes. And, blood pressure has a direct impact on heart diseases. So, it is essential to keep blood pressure levels under control. Go for regular check -ups and take prescribed medications for blood pressure.

This will improve overall fitness and health. It will help you lose weight and control cholesterol and blood pressure. Try to squeeze in at least 30 minutes of exercise e very day. Anything that increases heart rate will help.

Published : December 27, 2019 2:16 pm | Updated:December 27, 2019 2:30 pm

Original post:
Diabetes tips 2020 for a fit and healthy life - TheHealthSite

When you think about your preride prep, chances are, the coffee is just as important as the gels or energy bars you stash in your pockets. Which is good, because the health benefits of coffee, including a decreased risk of certain cancers, dementia, and stroke, are widely known. And while there is evidence that a cup of joe can also protect against the development of type 2 diabetes, new research out of Sweden found that the way you make your coffee might play a bigger role in the diseases prevention than previously thought.

In the study, published in the Journal of Internal Medicine, researchers looked at data from 421 participants in the Vsterbotten Intervention Program (1991 to 2005) who, after about seven years, developed type 2 diabetes and compared them to 421 participants who stayed healthy.

They looked at specific biomarkers in the participants blood samples (that were frozen from the Vsterbotten Intervention Program) and found that those who drank two to three cups of filtered coffee a day were 60 percent less likely to develop type 2 diabetes than those who drank only one cup of filtered coffee a day. However, drinking unfiltered coffeeboiled, K-cups, or French press, for examplehad no effect on type 2 diabetes risk.

So whats the deal? While researchers dont know for sure, the compounds in coffee that are known to elevate your blood lipid and homocysteine (an amino acid) levelswhich could lead to type 2 diabetesget captured in the filter paper and dont actually make it into the coffee you end up drinking, according to Rikard Landberg, Ph.D., study coauthor and head of the Division of Food and Nutrition Science at Chalmers University of Technology.

While this may seem alarming, Landbergs takeaway is still a positive one: Coffee isnt detrimental to your overall health. Intake of two to three cups per day could make a significant contribution to a healthy lifestyle for prevention of type 2 diabetes, he told Bicycling.

[Find 52 weeks of tips and motivation, with space to fill in your mileage and favorite routes, with the Bicycling Training Journal.]

While this specific study found that filtered coffee may be best for prevention, coffee, in general, contains chromium, which helps your body utilize insulin (a hormone that regulates your blood sugar).

So if you have a family history of diabetes or simply want to reduce your chances of developing it later in life, go ahead and sip a cup for a jolt of caffeine in the morning as well as an afternoon pick-me-up. Itll do more than just wake you up.

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Could the Way You Make Your Coffee Impact Your Health? - Bicycling

Diabetes is a troublesome disorder that can cause havoc on the body. According to the International Diabetes Federation, approximately463 million adultswere living with diabetes in 2019 and by 2045 this number is set to rise to700million.

Furthermore, theproportion ofpeople with type 2 diabetes is increasingin most countries. Now, a new study has found that "fat over-spills from the liver into the pancreas" may be what is responsible for triggering type 2 diabetes.

RELATED:WEIGHT TRAINING CAN CONTROL DIABETES IN OBESE PEOPLE

The research followeda group of people who had type 2 diabetes but had lost weight and successfully reversed the condition.The researchers uncovered that type 2 diabetes is caused as a response to too much fat in the body.

We saw that when a person accumulates too much fat, which should be stored under the skin, then it has to go elsewhere in the body. The amount that can be stored under the skin varies from person to person, indicating a personal fat threshold above which fat can cause mischief," said in a statementProfessor Roy Taylor, from theNewcastle University Institute of Translational and Clinical Research,

When fat cannot be safely stored under the skin, it is then stored inside the liver and over-spills to the rest of the body including the pancreas. This clogs up the pancreas, switching off the genes which direct how insulin should effectively be produced, and this causes Type 2 diabetes.

The study brings good news for type 2 diabetes sufferers as it indicates that the condition is reversible. In fact,previous Newcastle studies that found that type 2 diabetes can be reversed led to the large DiRECT trial.

This trial found that weight loss techniques combined with a low-calorie diet resulted in a remission of type 2 diabetes.

This means we can now see type 2 diabetes as a simple condition where the individual has accumulated more fat than they can cope with," said Taylor.

Importantly this means that through diet and persistence, patients are able to lose the fat and potentially reverse their diabetes. The sooner this is done after diagnosis, the more likely it is that remission can be achieved.

Originally posted here:
Excess Fat That Spills From the Liver into the Pancreas May Cause Type 2 Diabetes - Interesting Engineering

DexCom, Inc. has partnered with Tandem Diabetes Care in the UK,Sweden,Italy, andSpainto distribute the Dexcom G6 CGM System integrated with the Tandem Diabetes Care t:slim X2 insulin pump for people with diabetes.

Tandems t:slim X2 insulin pump with Basal-IQ technology uses Dexcom G6 CGM readings to predict glucose levels 30 minutes ahead and suspend insulin delivery when glucose is predicted to go low.

Insulin delivery resumes as soon as sensor glucose values begin to rise. The use of the integrated system reduced the time spent below 3.9 mmol/L (70 mg/dL) by 31 percent compared to the use of a CGM-integrated pump without automated insulin suspension1.

Combining the Dexcom G6 with Tandems t:slim X2 insulin pump will meaningfully improve diabetes management. Not only does the system eliminate the need for fingersticks, but it also helps patients reduce the frequency and duration of low-glucose events, saidErik Bjorkman, Dexcoms General Manager for EMEA.

Also, with the Dexcom G6 app, users can share their glucose information with up to five people. Whether you are a parent of a child with diabetes or an adult, the Dexcom G6 lets you seamlessly keep track of glucose levels and enables the users care team to remotely monitor their loved ones for extra peace of mind.

The t:slim X2 insulin pump with Basal-IQ technology, combined with the Dexcom G6, presents a meaningful advancement in the automated insulin delivery category, offering people with diabetes a simple-to-use system that predicts and helps prevent lows with zero fingersticks, saidBrian Hansen, executive vice president and chief commercial officer for Tandem Diabetes Care.

Some of the Dexcom G6 features include:

The CE Marking confirms that the G6 system meets the Essential Requirements of the Medical Device Directive MDD 93/42/EEC as amended by 2007/47/EC.

The powerful and ground-breaking new system is also the first CGM system to receive the US Food and Drug Administrations (FDA) De Novo classification.

With this new classification, the Dexcom G6 CGM system is indicated for use as both a stand-alone CGM and for integration into automated insulin dosing (AID) systems.

For more information on Dexcom G6, visitwww.dexcom.com/global.

Source:

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Dexcom Partners With Tandem Diabetes Care on Insulin Pump in Parts of Europe - dLife.com

Ive been on a real insulin-resistance kick lately. Its imperative that all people with diabetes understand the causes of insulin resistance and thus the importance of reducing it with a healthy diet and active lifestyle.

Causes of insulin resistance are multi-factorial. First: obesity, specifically abdominal obesity. This is primarily due to a high circulation of free fatty acids and unwanted fat deposits in the muscles and liver (enlarged adipose tissues at max capacity). This process causes chronic inflammation, resulting in a decrease in protective metabolic regulators and an increase in inflammatory mediators. These mediators have been directly associated with increased insulin levels (or insulin requirements). This inflammatory process can also occur high fat diets.

Lipoatrophy, the partial or complete loss of adipose tissue, and lipodystrophy, unwanted fat deposits in the muscles or liver (fatty liver), have also been associated with insulin resistance. The reason for this is unclear, but it is hypothesized that this condition results in a decrease in insulin receptor expression and insulin signaling. People with PCOS are also prone to higher levels of insulin resistance as a result of their associated generalized lipodystrophy. Acanthosis nigricans (Google it) is a common skin condition observed with lipodystrophy and is often seen in insulin resistant PWD.

Related: The 'Taboo' Type 1 Diabetes Medication: What to Know About GLP-1 Therapy

Research also shows a correlation between chronic stress and insulin resistance thanks to the hormone cortisol. In acute stress, cortisol stimulates production of glucose by the liver, designed to be immediately utilized in a fight-or-flight response. Chronic stress, however, is directly correlated with increased insulin requirements (endogenous or exogenous), a disruption of insulin signaling, and impaired overall insulin-mediated glucose uptake.

Menstruation tends to have a negative effect on insulin resistance, particularly just after ovulation. There is little research, but this phenomenon is thought to be due to the progesterone spike that happens during the luteal phase. Hopefully, there will be more research on this topic in the near future (insert empowering feminist comment here).

These are a few of the many contributors to insulin resistance. I havent even scratched the surface so I will likely do another post shortly. I just wanted to get some food for thought out to you all. Those of you who have been following me closely know that I have been attempting to decrease my insulin resistance with a low-fat, plant-based, whole-food diet. I have been on the diet for about a week thus far and have really been enjoying it! I have seen a reduction in my prandial insulin requirements, yet I have been eating more than I was when on my previous standard diet. Also, Ive really been enjoying fruits, something I used to stay away from!

The 'Taboo' Type 1 Diabetes Medication: What to Know About SLGT2 Inhibitors

How to Cope When Diabetes and Stress Become a Vicious Cycle

Why Continuous Glucose Monitors Are the Real MVP of Diabetes Management

Diabetes and Genetics: Is Your Child At Risk?

6 Ways to Pull Yourself Out of Diabetes Burnout

Read the original post:
What Every Person With Diabetes Should Know About Insulin Resistance - Yahoo Lifestyle

By Satchin Panda University of California San Diego Pam Taub University of California San Diego

People with obesity, high blood sugar, high blood pressure or high cholesterol are often advised to eat less and move more, but our new research suggests there is now another simple tool to fight off these diseases: restricting your eating time to a daily 10-hour window.

Studies done in mice and fruit flies suggest that limiting when animals eat to a daily window of 10 hours can prevent, or even reverse, metabolic diseases that affect millions in the U.S.

We are scientists - a cell biologist and a cardiologist - and are exploring the effects of the timing of nutrition on health. Results from flies and mice led us and others to test the idea of time-restricted eating in healthy people. Studies lasting more than a year showed that TRE was safe among healthy individuals. Next, we tested time-restricted eating (TRE) in patients with conditions known collectively as metabolic syndrome. We were curious to see if this approach, which had a profound impact on obese and diabetic lab rats, can help millions of patients who suffer from early signs of diabetes, high blood pressure and unhealthy blood cholesterol.

A leap from prevention to treatment

It's not easy to count calories or figure out how much fat, carbohydrates and protein are in every meal. That's why using TRE provides a new strategy for fighting obesity and metabolic diseases that affect millions worldwide. Several studies had suggested that TRE is a lifestyle choice that healthy people can adopt and that can reduce their risk for future metabolic diseases.

However, TRE is rarely tested on people already diagnosed with metabolic diseases. Furthermore, the vast majority of patients with metabolic diseases are often on medication, and it was not clear whether it was safe for these patients to go through daily fasting of more than 12 hours - as many experiments require - or whether TRE will offer any benefits in addition to those from their medications.

In a unique collaboration between our basic science and clinical science laboratories, we tested whether restricting eating to a 10-hour window improved the health of people with metabolic syndrome who were also taking medications that lower blood pressure and cholesterol to manage their disease.

We recruited patients from UC San Diego clinics who met at least three out of five criteria for metabolic syndrome: obesity, high blood sugar, high blood pressure, high level of bad cholesterol and low level of good cholesterol. The patients used a research app called myCircadianClock, developed in our lab, to log every calorie they consumed for two weeks. This helped us to find patients who were more likely to spread their eating out over the span of 14 hours or more and might benefit from 10-hour TRE.

We monitored their physical activity and sleep using a watch worn on the wrist. As some patients with bad blood glucose control may experience low blood glucose at night, we also placed a continuous glucose monitor on their arm to measure blood glucose every few minutes for two weeks.

Nineteen patients qualified for the study. Most of them had already tried standard lifestyle interventions of reducing calories and doing more physical activity. As part of this study, the only change they had to follow was to self-select a window of 10 hours that best suited their work-family life to eat and drink all of their calories, say from 9 a.m. to 7 p.m. Drinking water and taking medications outside this window were allowed. For the next 12 weeks, they used the myCircadianClock app, and for the last two weeks of the study they also had the continuous glucose monitor and activity monitor.

Timing is the medicine

After 12 weeks, the volunteers returned to the clinic for a thorough medical examination and blood tests. We compared their final results with those from their initial visit. The results, which we published in Cell Metabolism, were pleasantly surprising. We found most of them lost a modest amount of body weight, particularly fat from their abdominal region. Those who had high blood glucose levels when fasting also reduced these blood sugar levels. Similarly, most patients further reduced their blood pressure and LDL cholesterol. All of these benefits happened without any change in physical activity.

Reducing the time window of eating also had several inadvertent benefits. On average, patients reduced their daily caloric intake by a modest 8%. However, statistical analyses did not find strong association between calorie reduction and health improvement. Similar benefits of TRE on blood pressure and blood glucose control were also found among healthy adults who did not change caloric intake.

Nearly two-thirds of patients also reported restful sleep at night and less hunger at bedtime - similar to what was reported in other TRE studies on relatively healthier cohorts. While restricting all eating to just a six-hour window was hard for participants and caused several adverse effects, patients reported they could easily adapt to eating within a 10-hour span. Although it was not necessary after completion of the study, nearly 70% of our patients continued with the TRE for at least a year. As their health improved, many of them reported having reduced their medication or stopped some medication.

Despite the success of this study, time-restricted eating is not currently a standard recommendation from doctors to their patients who have metabolic syndrome. This study was a small feasibility study; more rigorous randomized control trials and multiple location trials are necessary next steps. Toward that goal, we have started a larger study on metabolic syndrome patients.

Although we did not see any of our patients go through dangerously low levels of glucose during overnight fasting, it is important that time-restricted eating be practiced under medical supervision. As TRE can improve metabolic regulation, it is also necessary that a physician pays close attention to the health of the patient and adjusts medications accordingly.

We are cautiously hopeful that time-restricted eating can be a simple, yet powerful approach to treating people with metabolic diseases.

The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.

Read more:
Limited eating times could be new way to fight obesity, diabetes - Sumter Item

Many people with diabetes also experience anxiety, and they may wonder whether there is a link between the two conditions.

Diabetes and anxiety are both among the leading causes of disability in developed countries around the world.

In the United States alone, anxiety affects close to 40 million adults. Diabetes is also common, with about 30.3 million U.S. adults living with this condition.

A 2013 meta-analysis revealed that people with diabetes face a higher likelihood than the general population of experiencing anxiety.

In this article, we outline the reasons for this association. We also describe the symptoms of both diabetes and anxiety, as well as how healthcare professionals diagnose each of these conditions.

People with diabetes are responsible for managing their blood sugar levels and ensuring that these stay within a healthy range. This task can be challenging and stressful.

Doctors will ask people with diabetes to remain mindful of their blood sugar levels and to engage in routine behaviors, such as:

Planning, checking, and being prepared for a wide range of challenges are all important for effective diabetes management. However, some people may worry excessively about their blood sugar levels or how their disease may progress. These concerns may trigger episodes of anxiety.

According to the National Library of Medicine, anxiety is "excessive worry or fear at real or imagined situations."

The emotional challenges of living with diabetes can also trigger anxiety.

Researchers report that anxiety affects about 40% of people with diabetes. This prevalence is much higher than that in the general U.S. population, where the condition affects 18.1% of people.

People with diabetes are at risk of developing low blood sugar, or hypoglycemia. Some of the symptoms of hypoglycemia are identical to those of anxiety.

Additionally, the results of a 2015 animal study suggest that experiencing several episodes of hypoglycemia can increase the likelihood of anxiety. The reason for this may be that hypoglycemic episodes trigger chemical and metabolic changes that physically affect the part of the brain that plays a role in processing anxiety.

The procedures that healthcare professionals use to diagnose diabetes and anxiety are quite different.

According to the Centers for Disease Control and Prevention (CDC), doctors diagnose diabetes using one or more of the following blood tests:

A person should see their doctor if they think that they have anxiety. The doctor may ask the person to fill in a questionnaire that asks about their psychological and physical symptoms.

In some cases, a doctor may refer the person for a mental health screening with a psychiatrist or psychotherapist. These mental health professionals will be able to carry out a more detailed assessment.

People with diabetes and anxiety must learn to distinguish between rational concerns over diabetes management and irrational, anxious thinking.

The first step in this process is to work closely with healthcare professionals to develop a diabetes treatment plan. This plan should include information on the following:

For people with anxiety, many different treatment options are available. A doctor or mental health professional may recommend one or more of the following approaches:

The combination of diabetes and anxiety can create a vicious cycle of physical and emotional problems. However, people who learn to manage their anxiety may find themselves better able to manage their diabetes.

Certain lifestyle practices can be beneficial for people with diabetes, anxiety, or both. These include:

Diabetes and anxiety are two serious yet common conditions, which can share some of the same symptoms.

People with diabetes are at increased risk of developing anxiety because they may experience excessive fear and worry about the management and possible progression of diabetes. Concerns over the physical symptoms themselves can also trigger anxiety.

Anxiety can, in turn, interfere with a person's ability to manage their blood sugar levels. Due to this, a person who has diabetes should see their doctor if they begin to experience symptoms of anxiety.

Many treatment options are available to help people deal with the symptoms of diabetes and anxiety. Certain lifestyle changes may also help with the management of both conditions.

Continue reading here:
Can diabetes cause anxiety? Blood sugar and other causes - Medical News Today

LOS ANGELES Until the recentapprovalofliraglutidefor the treatment of children and adolescents with type 2 diabetes, investigators likeSonia Caprio, MD,were at their wits' end watching the beta-cell function of their patients decline on metformin treatment.

"The kids were not doing well. It was like they were being treated with water," Dr. Caprio, a pediatric endocrinologist at Yale University, New Haven, Conn., said at the annual World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease.

For example, in the NIH-fundedTODAY(Treatment Options for Type 2 Diabetes in Adolescents and Youth) study thatbegan enrollment in 2004, 699 patients aged between 10 and 17 years and with type 2 diabetes were treated with metformin (1,000 mg, twice daily) to attain a glycated hemoglobin level of less than 8% and were then randomly assigned to continued treatment withmetforminalone or to metformin combined with rosiglitazone (4 mg, twice a day) or a lifestyle-intervention program that focused on weight loss through modifying eating and activity behaviors (N Engl J Med. 2012;366:2247-56).

Over the course of 11 months, the researchers found that 46% of the children were failing treatment. "The worst arm was the metformin arm," said Dr. Caprio, who was involved with the study. "Kids were not responding to the drug at all. About 52% of children failed to do better using metformin a classic drug that we all start kids on when we diagnose them with type 2 diabetes."

Findings from a follow-up study,TODAY2, showed that these young patients were prone to serious diabetes-related events, such as heart attacks, chronic kidney disease, retinal disease, neuropathy, and complications in the offspring of pregnancies.

In addition, results from theRISE(Restoring Insulin Secretion) Pediatric Medication Study found that, in youth with impaired glucose tolerance or recently diagnosed type 2 diabetes, neither 3 months of insulin glargine followed by 9 months of metformin nor 12 months of metformin alone halted the progressive deterioration of beta-cell function (Diabetes Care. 2018;41:1717-25).

"The uniqueness ofRISEis that we employed very sophisticated techniques to measure insulin secretion and sensitivity while they were being treated with these usual drugs," said Dr. Caprio, who was one of the study investigators. "The beta cell is unresponsive to metformin and other treatments. The question is, why?"

Despite these findings, 2018 consensus guidelines from the American Diabetes Association on the evaluation and management of youth-onset diabetes (Diabetes Care. 2018;41:2648-68) call for the administration of metformin twice daily in youth with new-onset diabetes who have a hemoglobin A1c(HbA1c)level of less than 8.5%. "I argue that is not the way. We need better ways to treat [these patients] because they are moving fast to having complications," she said.

Enter theEllipse Trial, a pivotal multicenter, randomized study that evaluated the effect of the glucagonlike peptide-1 receptor agonist liraglutide in children and adolescents with type 2 diabetes (N Engl J Med. 2019;381:637-46).

Researchers, led byWilliam V. Tamborlane, MD, chief of Yale Medicine Pediatric Endocrinology, also in New Haven, randomized 135 patients to one of two arms: 66 to subcutaneous liraglutide (up to 1.8 mg/day) and 69 to placebo for a 26-week, double-blind period, followed by a 26-week open-label extension period. All patients received metformin during the trial. More than half of the study participants (62%) were female, the mean age was 15 years, 65% were white, the mean body mass index was 33.9 kg/m2, their mean fasting glucose was 8.4 mmol/L, and their mean HbA1cwas 7.8%.

At 26 weeks, the mean glycated hemoglobin level had decreased by 0.64 percentage points with liraglutide and increased by 0.42 percentage points with placebo,for an estimated treatment difference of 1.06 percentage points (Pless than .001). By 52 weeks, the difference increased to 1.30 percentage points.

"There was also a significant drop in BMIzscore in patients treated with liraglutide, which is important," Dr. Caprio said. "This medication is having an impact on weight, which is a key driver of the onset of type 2 diabetes in youth. This is a remarkable achievement because weight loss is hard to achieve in obese adolescents, as we showed in the TODAY study."

The number of adverse events reported by patients was similar in the treatment and placebo groups (85% and 81%, respectively), but the overall rates of adverse events and gastrointestinal adverse events were higher with liraglutide.

"I use liraglutide just for weight reduction because I mainly see a lot of kids with obesity. Many kids are not responding because of the GI effects of this drug. I think the weight loss could have been better had the investigators moved to a dose of 1.8 mg, which we use in adults."

A fasting plasma glucose of 6.1 mmol/L was the primary reason for participants remaining on a lower dose of liraglutide, she said. At the same time, liraglutide concentration data indicated a high rate of noncompliance, which was expected in this population. "That's a big problem we face with children," Dr. Caprio said. "Some of them are not constantly taking the medication. They skip doses a lot. But that happens with patients in this age group."

"Finally, we have something else to help children and teenagers to delay the complications we are seeing," Dr. Caprio said. "To me, I think this is a new era. I have hope. It will be interesting to see whether liraglutide and perhaps SGLT2 [sodium-glucose transporter 2] inhibitors can delay the onset of type 2 diabetes in children. In my view, we will be doing this with drugs. I don't think the weight loss [concerns are] going to go away without medication, unfortunately."

Dr. Caprio reported having no financial disclosures.

This article originally appeared on MDEdge.com.

See original here:
Could Liraglutide Stall the Onset of Type 2 Diabetes in Kids? - Medscape

Scientists from various parts of the world involved in a $6 million dollar study have come up with an interesting revelation: Long-term remission from type 2 diabetes is possible just by losing 1 gram of fat from the pancreas. While this finding comes as a surprise to many, there are some facts about blood sugar that we are all aware of. Type 2 diabetes has a strong association with your lifestyle. What you eat determines your susceptibility to this condition and also, how well you can manage it.

Type 2diabetesaffects the bodys ability to either produce insulin or to use insulin effectively, you need treatment to keep your blood sugar levels within a normal range. Although there are numerous treatment options available to keep your blood sugar levels in control, home remedies can work wonders in achieving this task. Here are top 10 effective home remedies to maintain your blood sugar levels and lead a healthy life with diabetes.

The leaves of holy basil are packed with antioxidants and essential oils that produce eugenol, methyl eugenol and caryophyllene. Collectively these compounds help the pancreatic beta cells (cells that store and release insulin) to function properly and increase sensitivity to insulin. An added advantage is that the antioxidants present in the leaves help beat the ill effects of oxidative stress.

Tip: Consume two to three tulsi leaves whole or about one tablespoon full of its juice on an empty stomach to lower the blood sugar levels. Here are top 10 health benefits of tulsi.

Due to their high fibre content flaxseeds help digestion and aid in the proper absorption of fats and sugars. Consuming flax seed helps reduce a diabetics postprandial sugar level by almost 28 percent.

Tip: Consume one tablespoon of ground flaxseed powder every morning on an empty stomach with a glass of warm water. However, do not have more than 2 tablespoons per day, as it can be detrimental to your health. Here are 11 ways to include flaxseeds in your diet.

The leaves of bilberry have been used in Ayurveda for many centuries to control diabetes. Recently, the Journal of Nutrition stated that the leaves of the Bilberry plant contain high amounts of anthocyanidin, which enhance the action of various proteins involved in glucose transportation and fat metabolism. Due to this unique property, bilberry leaves are a great way to lower ones blood sugar levels.

Tip: Crush bilberry leaves in a mortar and pestle and consume 100 milligrams of this extract every day on an empty stomach.

Also known as dalchini, it improves insulin sensitivity and lower blood glucose levels. Having as little as teaspoon of cinnamon per day can improve ones insulin sensitivity and help controlling weight, thereby decreasing ones risk for heart disease.

Tip: Include about 1 gram of dalchini into your daily diet for about a month to help lower blood sugar levels. Read more health benefits of cinnamon.

Unlike other tea leaves, green tea is unfermented and is high in polyphenol content. Polyphenol is a strong antioxidant and hypo-glycaemic compound that helps control the release of blood sugars and helps the body use insulin better. Read more 10 types of flavoured green tea that have 20 health benefits.

Tip: Steep a bag of green tea in hot water for 2-3 minutes. Remove the bag and drink a cup of this tea in the morning or before your meals.

Also called moringa, the leaves of this plant are best known for their ability to boost ones energy. These have also been declared a superfood. In the case of diabetics, the moringa leaf increases satiety and slows the breakdown of food and lower blood pressure.

Tip: Take a few drumstick leaves, wash and crush them to extract their juice. Now take about 1/4th cup of this juice and drink it on an empty stomach, every morning to keep your sugar levels under control.

Also known as psyllium husk is often used as a laxative. When isabgol comes in contact with water, it swells to form a gel-like substance. This slows the breakdown and absorption of blood glucose. Isabgol also protects the stomach lining from ulcers and acidity.

Tip: Cosume isabgol after every meal, ideally with milk or water. Avoid having it with curd as it can lead to constipation. Read in detail about 8 health benefits of isabgol or psyllium husk you didnt know.

Bitter gourd is rich in plant insulin-polypeptide-P, a bio-chemical that mimics the insulin produced by the human pancreas and thus, reduces sugar levels in the body. It is also known to be highly beneficial for diabetics owing to thetwo very essential compounds called charatin and momordicin, which are the key compounds in lowering ones blood sugar levels.

Tip: Consume karela at least once a week either as a subzi or in a curry. If you want quick results, try having a glass of karela juice on an empty stomach once in three days. Read more about 8 healthy reasons to drink bittergourd or karela juice!

Found abundantly in India, the bitter leaf has a number of amazing medicinal properties. Neem enhances insulin receptor sensitivity, helps improve blood circulation by dilating the blood vessels, lowers blood glucose levels and reduces ones dependence on hypoglycemic drugs. Here are more health benefits of neem.

Tip: Drink the juice of the tender shoot of neem leaves on an empty stomach for best results.

A glycoside present in the seeds of Indian blackberry prevents the conversion of starch to sugar. It lowers blood sugar and helps prevent insulin spikes. Jambul also has properties that can protect you from heart diseases and other vascular disorders.

Tip: Eat around 5 6 jamuns in the morning to control your blood sugar levels. Alternatively, you can also add a spoonful of jamun seeds powder to a glass of warm water or milk and drink this daily for better control of diabetes.

Published : December 16, 2019 4:10 pm | Updated:December 17, 2019 11:06 am

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Top 10 diabetes home remedies that tame your blood sugar levels - TheHealthSite