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2020 Study on Digital Health: Diabetes Apps and Virtual Coaching – ResearchAndMarkets.com – Business Wire

Wednesday, April 1st, 2020

DUBLIN--(BUSINESS WIRE)--The "Digital Health: Diabetes Apps and Virtual Coaching" report has been added to ResearchAndMarkets.com's offering.

This special technology-based report provides an overview of diabetes, wearable glucose monitoring devices, smartphone-based digital health technologies, and attempts to answer the question: can digital health help improve diabetes?

Smartphone-based digital health technologies are expected to transform the diabetes management market over the next decade by substantially improving diabetes outcomes and reducing healthcare costs. These technologies are engaging and empowering patients, improving glycemic control, and lowering complications.

Digital health technologies are defined in this report as: diabetes smartphone apps integrated with blood glucose monitoring devices (both standard blood glucose meters and continuous glucose monitoring systems) and personalized virtual diabetes coaching services.

The adoption of smartphone-based digital health technologies for diabetes management is being driven by:

Key Topics Covered

Executive Summary

i. Digital health is transforming diabetes management

ii. Benefits

iii. Clinical data

iv. Limitations

v. Security concerns

vi. Conclusion

vii. Bibliography

1. Diabetes Overview

1.1 Type 1 diabetes: 5% of the diabetes population are insulin dependent

1.2 Type 2 diabetes: 95% of the diabetes population

1.3 Diabetes prevalence: rising by 50% over next 25 years

1.4 Complications: tight glycemic control can prevent complications

1.5 Prevention

1.6 Bibliography

2. New Guidelines for Achieving Glycemic Control

2.1 ADA's target A1c: 2019 Standards of Medical Care in Diabetes

2.2 The importance of self-monitoring of blood glucose

2.3 The DCCT study

2.4 New 2019 ADA guidelines for glycemic targets: time-in-range

2.5 Medtronic's TIR goa

2.6 Bibliography

3. Blood Glucose Monitoring and the Rise of Smartphone-Driven Diabetes Apps

3.1 Ascens

3.2 DarioHealth

3.3 LifeScan

3.4 Welldoc's BlueStar for diabetes

3.5 Glooko

3.6 mySugr

3.7 Bibliography

Exhibit 3-1: Selected standard blood glucose meters and diabetes apps

Exhibit 3-2: OneTouch Verio Flex and OneTouch Reveal app

Exhibit 3-3: OneTouch Reveal Plus powered by Welldoc's BlueStar technology

Exhibit 3-4: Welldoc's BlueStar AI-driven smart diabetes app

Exhibit 3-5: Glooko Mobile app

Exhibit 3-6: mySugr app

4. Virtual Diabetes Coaching

4.1 Lark Technologies

4.2 Livongo

4.3 Onduo

4.4 One Drop

4.5 Virta Health

4.6 Bibliography

Exhibit 4-1: Onduo for diabetes

Exhibit 4-2: The One Drop digital diabetes management portfolio

Exhibit 4-3: Virta app

5. Revolutionary Continuous Glucose Monitoring Systems

5.1 Abbott

5.2 Dexcom

5.3 Medtronic

5.4 Nemaura Medical

5.5 Senseonics

5.6 Bibliography

Exhibit 5-1: Selected continuous glucose monitoring systems with diabetes app

Exhibit 5-2: The FreeStyle Libre CGM 14-day sensor and LibreLink app

Exhibit 5-3: The Dexcom G6 CGM System with extended 10-day sensor

Exhibit 5-4: Dexcom CLARITY diabetes management software-

Exhibit 5-5: The Guardian Connect CGM System with Sugar.IQ app

Exhibit 5-6: The SugarBEAT system

Exhibit 5-7: The Eversense CGM and mobile app

6. Clinical data - Can Digital Health Help Improve Diabetes?

6.1 Meaningful Reduction in HbA1c

6.2 Clinical review of diabetes apps/digital health technologies

6.3 Emerging full-service virtual diabetes clinics

6.4 Bibliography

Exhibit 6-1: Selected studies, average reduction in HbA1c with use of diabetes apps and/ or digital app-based coaching programs

Companies Mentioned

For more information about this report visit https://www.researchandmarkets.com/r/gz9guz

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Exercise improves heart function in diabetes, while diet reverses the condition, finds study – Clinical Daily News – McKnight’s Long Term Care News

Wednesday, April 1st, 2020

News > Clinical Daily News

A new study has shown that exercise may be the best way to improve heart function in adults with type 2 diabetes but a specialized diet can reverse the condition.

Heart failure is a common complication of diabetes, and signs of future trouble can show up as changes to heart function in younger adults. Investigators compared the impact of supervised aerobic exercise and a low-energy meal replacement program on heart function in 87 patients ages 18 to 65 with the disease.

Participants underwent echocardiography and magnetic resonance imaging to confirm early heart dysfunction, and exercise tests to measure cardiovascular fitness.

Significant improvements in heart function were found in exercise program participants when compared with a control group. These patients also had an increase in exercise capacity. In contrast, the low energy diet did not improve heart function, but the intervention certainly wasnt a total loss. Patients in the diet group not only had favorable changes to heart structure and vascular function, but 83% in this cohort experienced a reversal of their diabetes, reported Prof. Gerry McCann, from the University of Leicester, United Kingdom.

It may seem obvious, but if we can empower patients with type 2 diabetes to make changes to their daily routines through exercise and healthy eating, we may help them reduce the risk of heart failure and even early death, McCann concluded.

Full findings were published in Diabetes Care.

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Living drug factories might treat diabetes and other diseases – MIT News

Wednesday, April 1st, 2020

One promising way to treat diabetes is with transplanted islet cells that produce insulin when blood sugar levels get too high. However, patients who receive such transplants must take drugs to prevent their immune systems from rejecting the transplanted cells, so the treatment is not often used.

To help make this type of therapy more feasible, MIT researchers have now devised a way to encapsulate therapeutic cells in a flexible protective device that prevents immune rejection while still allowing oxygen and other critical nutrients to reach the cells. Such cells could pump out insulin or other proteins whenever they are needed.

The vision is to have a living drug factory that you can implant in patients, which could secrete drugs as-needed in the patient. We hope that technology like this could be used to treat many different diseases, including diabetes, says Daniel Anderson, an associate professor of chemical engineering, a member of MITs Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science, and the senior author of the work.

In a study of mice, the researchers showed that genetically engineered human cells remained viable for at least five months, and they believe they could last longer to achieve long-term treatment of chronic diseases such as diabetes or hemophilia, among others.

Suman Bose, a research scientist at the Koch Institute, is the lead author of the paper, which appears today in Nature Biomedical Engineering.

Protective effect

Patients with type 1 diabetes usually have to inject themselves with insulin several times a day to keep their blood sugar levels within a healthy range. Since 1999, a small number of diabetes patients have received transplanted islet cells, which can take over for their nonfunctioning pancreas. While the treatment is often effective, the immunosuppressant drugs that these patients have to take make them vulnerable to infection and can have other serious side effects.

For several years, Andersons lab has been working on ways to protect transplanted cells from the hosts immune system, so that immunosuppressant drugs would not be necessary.

We want to be able to implant cells into patients that can secrete therapeutic factors like insulin, but prevent them from being rejected by the body, Anderson says. If you could build a device that could protect those cells and not require immune suppression, you could really help a lot of people.

To protect the transplanted cells from the immune system, the researchers housed them inside a device built out of a silicon-based elastomer (polydimethylsiloxane) and a special porous membrane. Its almost the same stiffness as tissue, and you make it thin enough so that it can wrap around organs, Bose says.

They then coated the outer surface of the device with a small-molecule drug called THPT. In a previous study, the researchers had discovered that this molecule can help prevent fibrosis, a buildup of scar tissue that results when the immune system attacks foreign objects.

The device contains a porous membrane that allows the transplanted cells obtain nutrients and oxygen from the bloodstream. These pores must be large enough to allow nutrients and insulin to pass through, but small enough so that immune cells such as T cells cant get in and attack the transplanted cells.

In this study, the researchers tested polymer coatings with pores ranging from 400 nanometers to 3 micrometers in diameter, and found that a size range of 800 nanometers to 1 micrometer was optimal. At this size, small molecules and oxygen can pass through, but not T cells. Until now, it had been believed that 1-micrometer pores would be too large to stop cellular rejection.

Drugs on demand

In a study of diabetic mice, the researchers showed that transplanted rat islets inside microdevices maintained normal blood glucose levels in the mice for more than 10 weeks.

The researchers also tested this approach with human embryonic kidney cells that were engineered to produce erythropoietin (EPO), a hormone that promotes red blood cell production and is used to treat anemia. These therapeutic human cells survived in mice for at least the 19-week duration of the experiment.

The cells in the device act as a factory and continuously produce high levels of EPO. This led to an increase in the red blood cell count in the animals for as long as we did the experiment, Anderson says.

In addition, the researchers showed that they could program the transplanted cells to produce a protein only in response to treatment with a small molecule drug. Specifically, the transplanted engineered cells produced EPO when mice were given the drug doxycycline. This strategy could allow for on-demand production of a protein or hormone only when it is needed.

This type of living drug factory could be useful for treating any kind of chronic disease that requires frequent doses of a protein or hormone, the researchers say. They are currently focusing on diabetes and are working on ways to extend the lifetime of transplanted islet cells.

This is the eighth Nature journal paper our team has published in the past four-plus years elucidating key fundamental aspects of biocompatibility of implants. We hope and believe these findings will lead to new super-biocompatible implants to treat diabetes and many other diseases in the years to come, says Robert Langer, the David H. Koch Institute Professor at MIT and an author of the paper.

Sigilon Therapeutics, a company founded by Anderson and Langer, has patented the use of the THPT coating for implantable devices and is now developing treatments based on this approach.

The research was funded by JDRF. Other authors of the paper include Lisa Volpatti, Devina Thiono, Volkan Yesilyurt, Collin McGladian, Yaoyu Tang, Amanda Facklam, Amy Wang, Siddharth Jhunjhunwala, Omid Veiseh, Jennifer Hollister-Lock, Chandrabali Bhattacharya, Gordon Weir, and Dale Greiner.

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People with diabetes are at high risk for coronavirus complications. Heres how to stay safe. – NJ.com

Wednesday, April 1st, 2020

The last time Sahar Hillel left the house beyond going to work or walking her dog was March 7.

Even then, she wore blue latex lab gloves nearly everywhere she went. Now she has her mom do her grocery shopping and has limited her trips to solitary walks with her Catahoula golden retriever mix, Wilbur.

Weeks before Gov. Phil Murphy issued a stay-at-home order to state residents, Hillel already had hunkered down, taking every precaution against the coronavirus.

A Type 1 diabetic for eight years, Hillel, 23, had seen how the disease made it difficult for her body to fight off even minor infections. Now, the East Brunswick resident is not taking any chances exposing herself to the potentially deadly novel virus.

Ive basically been in isolation for three weeks, Hillel said. With diabetes, you can end up in the hospital for little things. But this is not the time to end up in the hospital for something.

Hillel already heeded a dire warning now being issued by some health officials: People with diabetes are at high risk for serious complications from COVID-19 and should take extra precautions.

Older adults and people who have serious underlying medical conditions such as heart disease, chronic lung disease or severe obesity also are vulnerable, according to the Centers for Disease Control and Prevention. But early studies from China, as well as growing evidence in the United States, suggest people with diabetes should be especially vigilant.

Of 191 adults diagnosed with the virus early on in Wuhan, China the epicenter of the pandemic about half had underlying medical conditions, most commonly diabetes and high blood pressure, according to a study by Chinese doctors. Fifty-four of them died, with diabetes or coronary heart disease emerging as factors increasing the likelihood of death.

People with diabetes who contracted the coronavirus had a fatality rate of 7%, according to a CDC report based on 44,000 confirmed cases in China as of Feb. 11. The rate for those without an underlying medical condition was just 0.9%.

More than 30 million people in the United States or about 10% of the population have diabetes, according to the CDC. In 2017, it was the seventh-leading cause of death in the country.

Its safe to say people with diabetes should be considered among those at risk for worse outcomes with a COVID-19 infection, said Robert H. Eckel, president of science and medicine at the American Diabetes Association. The patient with diabetes needs to wake up to the fact that they will be at increased risk, and if they get the infection, they do less well.

Sahar Hillel with her dog, Wilbur.

The message came into focus early in New Jersey. During a press briefing March 10, state officials announced the first person in the state to die from coronavirus was a 69-year-old man from Bergen County with a history of health issues including diabetes.

Type 2 diabetics, who make up the majority of people with diabetes, tend to deal with chronic, low-grade inflammation that causes the immune system to operate at an abnormal state, according to Eckel. In addition, the bodys ability to fight infection by mounting a white blood cell count is impaired, Eckel said.

Taken together, diabetics have trouble fighting viral and bacterial infections, while also at increased risk of contracting common infectious diseases.

Diabetes is a condition that predisposes to many complications, some of which are short term, while others are more long term, said Michael Steinberg, chief of general internal medicine and vice chair for research at Robert Wood Johnson Medical School in New Brunswick.

Diabetes has an impact on overall immune system functioning, and elevated blood sugars themselves can increase infection risk. Therefore, people with diabetes may be at increased risk of many infections, possibly including COVID-19.

Eckel said more research is needed to fully understand the relationship between diabetes and coronavirus.

Patients with diabetes doing more poorly with this specific infection has been suggested by the Chinese, he said. But we dont have an adequate data collection in the U.S. yet to really know whether this is going to play out here.

With coronavirus spreading across New Jersey state numbers swelled to 4,402 cases and 62 deaths as of Wednesday Steinberg and Eckel said people with diabetes should be extra vigilant.

Diabetics should maintain healthy diets, exercise, limit exposure and make certain their blood sugar levels remain in optimal range.

This includes making sure they have an ample supply of their medications and that they take them regularly, Steinberg said. We know that elevated blood sugar can increase risk of infections, and this likely includes pulmonary infections, such as COVID-19.

Hillel already is heeding that advice. Diagnosed with diabetes when she was 15, the Middlesex County resident has taken health precautions for almost a decade. When she saw coronavirus reached Seattle in February, she thought it was a matter of time before it made its way to New Jersey.

She began working from home March 16.

I recognized what was going to happen, Hillel said. Im a little more conscious of stuff like that than everyone else.

I literally havent gone anywhere, she added. The last time I went to the grocery store was March 7.

Steinberg and Eckel said Hillel is making all the right decisions.

Be safe, stay at home, take your medications and avoid contact with others who could spread the infection, Steinberg said.

Matthew Stanmyre may be reached at mstanmyre@njadvancemedia.com. Follow him on Twitter @MattStanmyre. Find NJ.com on Facebook.

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Young teacher with type 1 diabetes and lung condition conquers COVID-19 – Diabetes.co.uk

Wednesday, April 1st, 2020

A young secondary school-teacher with type 1 diabetes has spoken about recovering from COVID-19, her experience, her symptoms, and how she conquered it.

Sarah Hall also has a condition called Alpha-1 antitrypsin (A1AT) which affects her lungs and liver, putting her at a greater risk of the virus.

The account begins when the 26-year-old started feeling tired at the beginning of March, she told the Daily Telegraph. She initially put the fatigue down to the stresses of teaching. However, the next day she developed a cough and felt like she was freezing cold.

She was advised to self-isolate by her work, and rang the NHS 111 operator who said it sounded like she had developed COVID-19.

Sarah said: I struggled to breathe and felt constantly dizzy I felt like I was about to pass out. But I tried to keep calm, drink plenty of water and keep as busy as I could.

Overall, her symptoms included:

At one point Sarah thought she was feeling better and was over the worst, but in just a couple of days she began sweating, vomiting and struggling to breathe.

She said: At this point Im unsure whether to go to hospital. I feel as though Ill be wasting valuable resources and I may be an infection risk to vulnerable patients.

At 7pm on Saturday night I ring NHS 111 again. Im in a really bad way. We wait nine hours for an ambulance to arrive and face-to-face assess me.

When the ambulance still does not appear, it is suggested that Sarah gets herself to hospital. She is admitted and eventually tested positive for COVID-19.

She said: I was severely dehydrated so was ordered fluids, and then sent back home. By day seven of the virus I felt better and the symptoms started to lessen. My birthday was ruined though I couldnt blow out candles!

Its not pleasant but I have a lung condition as well as diabetes and I conquered the virus.

The illness is the first of its kind to have such a global impact in living memory, but Sarahs story of conquering the virus shows that it is not all doom and gloom. There are many things you can do to protect yourself and keep yourself safe. For more information, you can refer to the Government website or view our coronavirus coverage and what you should be doing to follow the government guidelines.

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AADE7 Self-Care Behaviors revised in new guidance from the Association of Diabetes Care & Education Specialists – Newswise

Wednesday, April 1st, 2020

Newswise The revised framework for the AADE7 Self-Care Behaviors published this week in the April issue of The Diabetes Educator journal. As the foundation of diabetes self-management care and support, updates to the framework reflect growing shifts in diabetes, prediabetes and cardiometabolic care since their last update in 2010.

This update is in response to a broader change in how we now think about self-management, from linear behaviors we review on a list, to overlapping, connected lifestyle changes that build on each other, said Kellie Antinori-Lent, MSN, RN, ACNS-BC, BC-ADM, CDCES, FADCES, 2020 president of the Association of Diabetes Care & Education Specialists. Each behavior is, at its core, person-centered and that means we start with the person with diabetes and their readiness to change and sustain change. What barriers do they experience and how must we help them overcome those barriers?

Key trends from the revision include:

Expanded role of the diabetes care and education specialist

Increasing integration of technology into self-care

Greater awareness of social determinants of health

To read the revised framework, visit DiabetesEducator.org/AADE7behaviors.

About the Association of Diabetes Care & Education Specialists: ADCES is an interdisciplinary professional membership organization dedicated to improving prediabetes, diabetes and cardiometabolic care through innovative education, management and support. With more than 12,000 professional members including nurses, dietitians, pharmacists and others, ADCES has a vast network of practitioners working to optimize care and reduce complications. ADCES supports an integrated care model that lowers the cost of care, improves experiences and helps its members lead so better outcomes follow. Learn more at DiabetesEducator.org, or visit us on Facebook or LinkedIn (Association of Diabetes Care & Education Specialists), Twitter (@ADCESdiabetes) and Instagram (@ADCESdiabetes).

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10 Unexpected Things That Happen to Your Body if Diabetes Goes Untreated – msnNOW

Wednesday, April 1st, 2020

When you hear diabetes, your mind likely jumps to problems with producing insulin and regulating blood sugar. And thats definitely a key part of this chronic disease, which affects nearly 1 in 10 Americans, according to the Centers for Disease Control and Prevention (CDC). But thats also just the tip of the iceberg.

Diabetes is like termites, in that it causes slow, hidden, but significant damage in the body, says Osama Hamdy, M.D., Ph.D., director of the Inpatient Diabetes Program at the Joslin Diabetes Center in Boston. Most patients with type 2 diabetes die from a heart attack, Dr. Hamdy says, but because the disease doesnt have many symptoms, people tend to take it lightly.

And evidence continues to mount that diabetes affects every system in the body, wreaking havoc if its not well managed. Learn more below about the side effects of diabetes and how you can protect yourself from complications. (The good news: Most can be avoided by following the treatment plan set out by your doctor.)

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Why people with diabetes, like Tom Hanks, may be at increased risk of coronavirus – USA TODAY

Sunday, March 15th, 2020

Tom Hanks and his wife Rita Wilson have tested positive for coronavirus while working in Australia. USA TODAY

As the new coronavirus spreads and sickens more people in the USA, people with preexisting health conditions areat particular risk, public health officials say.

Actor Tom Hanks, who revealed that he was living with Type 2 diabetes in 2013, confirmed Wednesday that he and his wife tested positive for the coronavirus that causes COVID-19.

People with diabetes are among those at increased risk for complications from COVID-19, the Centers for Disease Control and Prevention says.

That's becausefluctuations in blood glucose levelsand possible diabetes complications can make it harder to treat a viral infection, the International Diabetes Federationsays.

The latest on coronavirus: EU rips travel ban; US stocks struggle; NBA suspends season; US death toll at 38

Though doctors are still learning what exactly puts someone at higher risk for developing a severe illness with COVID-19, early information indicates older patients and those with chronic medical conditions may be at higher risk.

According to early data frommore than 44,000 confirmed casesin China as of Feb 11, deaths among patients who had diabetes were at 7%, compared with 0.9% for those without an underlying condition, the CDC says.

According to theInternational Diabetes Federation, there may be two reasons for the complications that can arise.

"Firstly, the immune system is compromised, making it harder to fight the virus and likely leading to a longer recovery period," the group wrote in its "Diabetes Voice" publication. "Secondly, the virus may thrive in an environment of elevated blood glucose."

Q&A: You asked us tons of questions about the coronavirus. We answered them.

"Diabetes affects healing in general," said Dr.Susan Spratt, an endocrinologist at Duke University. Patients who have diabetes can have an increased risk of taking more time to heal and get a secondary infection, Spratt said.

People with diabetes can't make enough or can't as effectively usethe insulin in their bodies, according to the CDC. Insulin helps people use sugar in their bloodstreams for energy. As the food we eat breaks down into sugar, or glucose, it is released into our blood, and our pancreas releases insulin to facilitate the process.

"When there isnt enough insulin or cells stop responding to insulin, too much blood sugar stays in your bloodstream. Over time, that can cause serious health problems, such as heart disease, vision lossand kidney disease," the CDC says.

When a patient's diabetes is uncontrolled, meaning blood sugar levels are not in a recommended range, this can especially contribute to heart or kidney problems, said Dr. Maria Pea, director of endocrine services at Mount Sinai Doctors Forest Hills in New York.

Having both problems with their heart or kidney and diabetes could worsenthe prognosis for patients with COVID-19, she said.

Another potential issue for patients with diabetes amid the COVID-19 outbreak is inflammation, saidPea.

Increased blood sugar can increase inflammation, as can viral infections,Pea said. With bothincreasinginflammation, this can increase the likelihood of a more severe complication, she added.

People with diabetes, even those with the condition well managed, are at a higher risk of complications from the flu as well, the CDC says.

Patients with Type 1 diabetes, caused when a person's immune system attacks the cells in their pancreas that create insulin, are at an increased risk fordiabetic ketoacidosis. "This can make fluid and electrolyte management even trickier when trying to manage sepsis," Spratt said.

According to research published Wednesdayin the medical journal The Lancet, sepsis and septic shock are among the severe complications observed in some COVID-19 cases.

The CDC recommends people with preexisting conditions take everyday precautions to protect themselves from COVID-19. This includes avoiding contact with sick people, washing their hands regularly and not touching their face, among other measures.

Those who have a condition such as diabetes should make sure they're in contact with their doctor if they need extra medication or supplies, such astest strips or insulin.

The American Diabetes Associationrecommends gatheringsimple carbs such asregular soda, honey, jam,Jell-O, hard candies or popsicles.

"If you have diabetes and you have symptoms such as cough, high temperature and feeling short of breath, you need to monitor your blood sugar closely," Dan Howarth, head of care at Diabetes UK, said in a statement.

Follow USA TODAY's Ryan Miller on Twitter @RyanW_Miller

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Artificial Intelligence in Diabetes Management Industry to Generate Revenues of Over $1.26 Billion by 2024 – Infinium Global Research – Benzinga

Sunday, March 15th, 2020

PUNE, India, March 13, 2020 /PRNewswire/ -- Infinium Global Research has recently published a global report on "Artificial Intelligence in Diabetes Management Market(Device - Insulin Delivery Devices, Diagnostic Devices, and Glucose Monitoring Devices): Global Industry Analysis, Trends, Size, Share and Forecasts to 2024", the reported study estimated the market for artificial intelligence in diabetes management will reach up to USD 1264.7 million by 2024, with a compound annual growth rate of 47.5%, in the forecast period (2018-2024).

Digitization has made big data technologies more relevant in the healthcare environment. The propagation of smart devices has enhanced the transition to digitized healthcare. The smart apps have made self-management of diabetes by the patients affordable. Sensors are proficient in transmitting data to smart devices and diabetics can monitor their blood glucose levels on these devices. Pharmacogenetics and machine learning will help systems embedded with artificial intelligence to manage diabetes better than humans in the near future. Artificial intelligence algorithms bring about advanced glucose prediction methods that help in tackling diabetes effectively.

Furthermore, artificial intelligence is leveraging the avalanche of healthcare data and is improving patient outcomes for diabetes patients. Machine learning algorithms allow better diagnosis and monitoring resulting in enhanced patient-centric treatment. It is predicted that diabetes will extensively be managed by smart machines and artificial intelligence algorithms over the forecast period.

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Increasing Prevalence of Diabetes Globally

Diabetes is a medical condition wherein the inability of the pancreas to produce insulin causes augmented glucose levels in the body. Presently, the major part of the world is suffering from type 2 diabetes to a greater extent. Furthermore, genetics and an unhealthy lifestyle are considered as major causes of diabetes mellitus. Diabetics face various daily challenges such as dietary restrictions and regular administering of insulin. The anytime-anywhere nature of digital technology allows patients to address their health problems by connecting with the healthcare team and sharing data. This is creating a digital ecosystem of data driven tools that can associate patients and their care team for better management of diabetes.

Moreover, the government programs are running across the world in order to control diabetes. Numerous software companies come with an idea of several applications in diabetes management which would help in controlling and managing diabetes. Growing use of mobile phones permits these companies to design apps which directly or indirectly help to manage the diabetes mellitus.

Increasing Penetration of Connected Devices and other Wireless Technology Will Spur Revenue Growth

The global artificial intelligence in diabetes management market is anticipated to witness the exceptional growth during the estimated period. The growth is primarily associated with the increasing prevalence of the geriatric population across the globe. In addition, the rising prevalence of metabolic disorders together with increasing adoption of a torpid or sedentary lifestyle also contributes to boosting the growth of artificial intelligence in the diabetes management market.

However, few factors such as government regulation, a dearth of awareness, and high cost are the major restraints limiting the growth of artificial intelligence in the diabetes management market. Nevertheless, various research and technological developments are considered as better opportunities that help in bringing new growth paths for artificial intelligence in the diabetes management market over the forecast period.

Novel Solutions Offered by Several Companies and Digital Health Start-Ups Assist in Revenue Growth

The key players are investing in integrated Artificial Intelligence technology with other technologies such as the Internet of Things (IoT), Natural Language Processing (NLP), and Machine Learning (ML). Launch of the technologically advanced and economical system by key players in the market are projected to propel the growth of the market during the forecast period. Various companies are also providing a wide range of devices and software portfolio to offer advanced solutions to their customers.

Furthermore, mergers & acquisitions, strategic partnerships, collaboration, and agreement are some of the major strategies adopted by industry vendors to sustain competition in the market. For instance, in June 2019, Companion Medical, a leader in the development of advanced insulin delivery technology to improve diabetes care, and Glooko, a leader in diabetes data visualization and management, have declared an incorporated data partnership agreement that will permit insulin data from users of the InPen Smart Insulin Injection Pen to be integrated into the Glooko Enterprise diabetes data management system and Glooko Mobile App. This amalgamation will assist users to automatically incorporate their insulin data with the Glooko diabetes data management system for medical evaluation by their healthcare professionals.

Evolving Healthcare Infrastructure in Developing Nations Enables Market Growth in Asia Pacific

North America region is estimated to remain its dominance in artificial intelligence in the diabetes management market during the prediction period due to growing innovation in artificial intelligence-based solutions. Furthermore, North America is in the next phase of digitization of concepts like the Internet of Things, big data, robotics, and machine learning. Consequently, these digital technologies are expected to drive the regional market over the projection period. The Asia Pacific region is anticipated to witness an enormous growth in the near future owing to new product launches and a huge diabetes population base.

In addition, the Asia Pacific region is also witnessing numerous product launches. For instance, in May 2019, Roche Diabetes Care India introduced its Integrated Diabetes Management Solution (IDMS) program in India along with the introduction of the Accu-Chek Instant blood glucose monitoring (BGM) system and the My Sugar app. Moreover, the government of China is promoting the development of artificial intelligence in the healthcare sector and offering funds for smart healthcare facilities.

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Global Artificial Intelligence in Diabetes Management Industry Coverage

Chapter - 1 Preface

Chapter - 2 Executive Summary

Chapter - 3 Global Artificial Intelligence in Diabetes Management Market Overview

Chapter - 4 Artificial Intelligence in Diabetes Management Market Macro Indicator Analysis

Chapter - 5 Global Artificial Intelligence in Diabetes Management Market by Device

Chapter - 6 Global Artificial Intelligence in Diabetes Management Market by Region 2018-2024

Chapter - 7 Company Profiles and Competitive Landscape

Browsein-depth TOC on "Artificial Intelligence in Diabetes Management Market"

About Us

Infinium Global Research is a business consulting and market research firm; a group of experts that caters to fulfilling business and market research needs of leading companies in various industry verticals and business segments. The company also serves government bodies, institutes and non-profit/non-government organizations to meet their knowledge and information needs.

Through our information services and solutions, we assist our clients to improve their performance and assess the market conditions to achieve their organizational goals. Our team of experts and analysts are engaged in continuously monitoring and assessing the market conditions to provide the knowledge support to our clients. To help our clients and to stay updated with the advances and inventions in technology, business processes, regulations and environment, Infinium often conducts regular meets with industry experts and opinion leaders. Our key opinion leaders are involved in monitoring and assessing the progress in the business environment, so as to offer the best opinion to our clients.

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Defeating Diabetes: What you don’t know can kill you. Take the test – KTBS

Sunday, March 15th, 2020

Bossier, La. - More than 7-million American adults have diabetes and don't know it. That's about one in four people. And with diabetes, what you don't know can kill you.

There is absolutely no way to tell who in this crowd has diabetes, "You don't just go to bed one day and wake up the next and you're diabetic," says Endocrinologist, Laura E. Kimball-Ravari, M.D.

There are symptoms that go unnoticed leaving one-third of diabetes cases undiagnosed, "Changes and differences in your body from having high blood sugars can start early on," says Ravari. She adds, the sooner a person discovers they're diabetic the better.

"Diabetes is the leading cause of blindness in adults, the leading cause of kidney failure requiring hemodialysis, the leading cause of lower limb amputation," says Ravari.

Tiffany McCallister was just a toddler when her mother suspected something might be wrong, "She took me to the doctor and they said there was nothing wrong."

At that time, blood glucose tests weren't as accurate. Her mother got a second opinion, "And immediately smelled my breath and said she's a diabetic."

Tiffany has Type1. Diabetes typically considered the type that affects children, "But, they can also be diagnosed when they're much older, even 30's and 40's. But, they're usually a more slender build and are normally more fit," adds Ravari.

Still the first step is diagnosis which means knowing the symptoms. "You do have to look for the symptoms of diabetes, and some of the symptoms are being very hungry, being very tired, and maybe having some blurry vision," says Ravari.

Frequent urination is also a symptom. A person might also have cuts that don't properly heal.

Diagnosed as a toddler, to Tiffany managing diabetes is a way of life. Whether you're a Type 1 or Type 2 diabetic, going undiagnosed could be deadly, "I've had it a long time. And the best thing, take care of yourself and don't limit yourself."

If you are experiencing any of the symptoms - make an appointment with a doctor. The longer diabetes goes undiagnosed, the more damage it can cause. Prevalence of the disease is expected to increase by 54-percent in the next 10 years.

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Type 2 diabetes and coronavirus: How to lower risk of catching virus if you have diabetes – Express

Sunday, March 15th, 2020

Type 2 diabetes is not a major concern in and of itself, but if left untreated, the condition can lead to a number of deadly complications, such as heart disease. This is because your blood sugar levels are more prone to fluctuating if you have diabetes, and this mechanism damages blood vessels and impairs other vital bodily functions. There is now a threat that has been added to the list of potential complications: COVID-19.

COVID-19 is a new strain of virus that belongs to the coronavirus group, a family of respiratory infections.

The virus, which first broke out in the Wuhan province in China in December, has so far caused 124,933 cases worldwide and lead to 4,585 fatalities.

Scientists gathering data on the pathogen have revealed that infected people with diabetes are more prone to developing a serious illness.

It is believed that diabetes can weaken your immune systems defences, leaving you more susceptible to illness.

READ MORE:Type 2 diabetes: How much sleep you need each night to keep blood sugar levels in check

According to official reports, older people, those with a compromised immune system and those with high blood pressure or heart problems, are at an increased risk of developing a serious illness.

People with diabetes should also heed the advice issued to the general public on how to reduce the risk of catching and spreading the virus.

Thoroughly washing your hands with soap and water for at least 20 seconds is the most important measure.

Take notice of areas you might miss including the back of your hands, between your fingers and around the nails, advises Diabetes.co.uk.

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Prevent the silent epidemic of kidney disease – The Baxter Bulletin

Sunday, March 15th, 2020

Jim Miller, The Savvy Senior Published 3:47 p.m. CT March 15, 2020

Jim Miller(Photo: File)

Dear Savvy Senior,

Do kidney problems run in families? My mother died from kidney failure 10 years ago at age 74 but didnt know she had a kidney problem until it was too late.

Just Turned 60

Dear 60,

Anyone who has a family history of kidney disease, or who has high blood pressure or diabetes is at increased risk and needs to have their kidneys tested.

According to the Center for Disease Control and Prevention, around 37 million U.S adults have chronic kidney disease (when the kidneys cant properly do their job of cleaning toxins and wastes from the blood), and millions more are at risk of developing it, yet most people dont realize it. Thats because kidney disease develops very slowly over many years before any symptoms arise. But left untreated, the disease can eventually require people to spend hours hooked up to a dialysis machine or get a kidney transplant. Even mild kidney problems can double a persons risk of heart attack and stroke, as well as cause anemia and bone disease.

The reason kidney disease has become so widespread today is because of the rise of obesity, type-2 diabetes and high blood pressure which all strain the kidneys.

Another factor is the increasing number of people who take multiple medications, which can overtax the organs. People over age 60 are especially vulnerable both because they tend to take more drugs, and because kidney function normally declines somewhat with age.

Because kidney disease has no early symptoms, the only way to catch it before it advances is to have a simple blood and urine test by your doctor. So, anyone that has diabetes, high blood pressure or heart disease, a family history of kidney disease, or is age 60 or older needs to get tested. African, Hispanic, Asian and Indian Americans along with Pacific Islanders are also at increased risk.

If youre diagnosed with kidney disease you need to know that theres no cure, but there are steps you can take to help contain the damage, including:

Control your blood pressure: If you have high blood pressure, get it under 130/80. If you need medication to do it, ACE inhibitors and ARBs are good choices because of their proven ability to protect the kidneys.

Control your diabetes: If you have diabetes, keep your blood sugar as close to normal as possible.

Change your diet: This usually means reducing the amount of protein and phosphorus you eat and cutting back on sodium and possibly potassium. Your doctor can help you determine an appropriate eating plan, or you may want to talk to a dietitian.

Watch your meds: Dozens of commonly used drugs can damage the kidneys, especially when taken in high doses over long periods most notably NSAIDs like ibuprofen and naproxen. Herbal supplements can also be very dangerous. Talk to your doctor about all the prescription, over-the-counter and herbal products you take to identify potential problems and find alternatives.

Exercise and lose weight: If youre overweight and inactive, start an aerobic fitness routine (walk, swim, cycle, etc.) that gets your heart pumping. This will help lower blood pressure, control diabetes and help you lose excess weight all of which will help your kidneys.

Quit smoking: If you smoke, quit. Heart disease becomes a much greater risk to the kidneys if your smoke. Smoking also doubles the rate of progression to end-stage renal failure.

Limit alcohol intake: Drinking too much alcohol can worsen kidney disease too, so talk to your doctor to see if its safe for you to drink, and if so, limit yourself to no more than one drink per day.

Send your senior questions to: Savvy Senior, P.O. Box 5443, Norman, OK 73070, or visit SavvySenior.org. Jim Miller is a contributor to the NBC Today show and author of The Savvy Senior book.

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Wear The Gown: Rolling back diabetes with diet and exercise – KENS5.com

Sunday, March 15th, 2020

SAN ANTONIO For many who develop type-2 diabetes, they become reliant on medicationand, in many cases, more than one type. But it is possible to roll back diabetes and get off the medications with diet and exercise.

"It was eight-point-something and now we are down to 5.7, which is borderline diabetic. Anything under six is where I want to stay," said Armida Oliver, a diabetes patient for the past 10 years, while discussing her A1C number. "That was about two or three years ago. I'm down to just one medication and my numbers have been great."

At one point she was taking three medications: Metformin, Januvia, and Invokana. But thanks to diet and exercise, she managed to drop two of them, along with 55 pounds.

"I join my sisters for senior water aerobics every morning. We try Monday through Friday, but we are happy if we go four times a week," Oliver said.

Some of the benefits of exercise for diabetes includes lowered blood sugar levels, improved insulin sensitivity, reduced body fat, a lowered risk of heart disease and an enhanced quality of life.

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"Miss Oliver is really a model patient. She's the perfect example of someone who, through lifestyle modifications, has been able to not only get her diabetes under control, but really throwing the diabetes into what we call remission," said Dr. Alberto Chavez, an endocrinologist with the Texas Diabetes Institute within the University Health System.

He added there has been some debate about what diabetes remission really means.

"The bottom line is that it is a reality that patients can get off of medications or many amounts of medications by making meaningful lifestyle changes," Chavez said.

That is exactly what Oliver did in cutting her medications from three to one.

"I take it faithfully and I know that I can't have two donuts in one sitting," she said. "I'm not depriving myself, but, by the same token, I just limit myself."

For more information about family health, call (210)358-3045. You can also find the rest of Wear The Gown stories, just go to WearTheGown.com.

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Type 2 diabetes symptoms: The change in your breathing pattern to watch out for – Express

Sunday, March 15th, 2020

Type 2 diabetes is a condition whereby the pancreas does not produce enough of the hormone insulin to regulate glucose in your blood, a type of sugar that you get from food and drink. With the pancreas out of action, blood sugar levels rise uncontrollably. This process can damage blood vessels, causing a number of life-threatening complications, such as heart disease.

This internal mechanism largely goes undetected in the beginning so people with type 2 diabetes often live with the condition for years before getting diagnosed.

Over time, however, high blood sugar levels can produce a number of noticeable signs.

One major warning sign to watch out for is shortness of breath, according to Mayo Clinic.

This symptom arises when blood sugar levels cause toxic acids to build up in your blood and urine, explains the health body.

READ MORE:How to live longer: Three reasons why paprika spice may increase your life expectancy

It is important to note that becoming short of breath can also indicate kidney failure, the most severe stage of kidney disease.

As Diabetes.co.uk, kidney disease is one of the more common complications of diabetes, affecting about 40 percent of people with diabetes.

Other symptoms associated with consistently high blood sugar levels include:

If you recognise any of the above symptoms associated with type 2 diabetes, you should see a GP immediately, says the NHS.

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As the health body points out, the earlier diabetes is diagnosed and treatment started, the better.

After receiving a diabetes diagnosis, a GP will usually recommend revising your lifestyle to lower your blood sugar levels.

One key aspect of blood sugar management is to improve your diet.

One tried-and-tested way to reduce your blood sugar levels is to restrict your intake of high-carb foods.

Foods with a high-carb content are broken down into blood sugar relatively quickly and therefore has a more pronounced effect on blood sugar levels than either fat or protein.

High-carb culprits include starchy foods such as rice, pasta and flour (therefore including pastry, bread and other dough based foods).

Following the Glycemic Index (GI) can help you differentiate between low and high-carb foods.

The Glycemic Index (GI) is a relative ranking of carbohydrate in foods according to how they affect blood glucose levels.

Carbohydrates with a low GI value (55 or less) are more slowly digested, absorbed and metabolised and cause a lower and slower rise in blood glucose and, usually, insulin levels.

Carbs that rank low on the GI index include:

Many whole grain breads and cereals (like barley, whole wheat bread, rye bread, and all-bran cereal)

The other key component of blood sugar management is regular exercise.

According to the NHS, you should aim for 2.5 hours of moderate-intensity exercise a week to keep blood sugar levels in check.

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Coronavirus: how diabetes, asthma and other underlying health conditions affect how you cope – Telegraph.co.uk

Sunday, March 15th, 2020

As the number of UK cases of coronavirus continues to rise, what has become clear is how many of the patients to die from the virus have underlying health conditions that make them susceptible to catching it.

The death toll in Britain is up to 22. Of the latest deaths in the UK, eight were men aged over 80. All but one had known underlying health conditions.

Its a new infection, but from our experience with dealing with flu epidemics, we know that people with various conditions will fare worse, says Fan Chung, a professor of respiratory medicine at Imperial College. A paper has just published in the New England Journal of Medicine, that looked at the first 1,001 cases in Wuhan. The figures showed those with diabetes, high blood pressure, heart disease, COPD, cancer and renal disease, fared worse. And I suspect the people who very unfortunately died in the UK had one or any of those conditions."

A Chinese study hasfound people with heart disease, diabetes and cancer had a 79 per cent chance of being admitted to intensive care or dying from the virus, due to their weakened immune systems.

Here are the underlying health conditions that put you at higher risk of getting the coronavirus, anda reminder of how it might initially spread.

People with diabetes face a higher risk of complications if they get the coronavirus, due to the fact their fluctuating or elevated glucose levels leave them with lowered immunity. This also means they have less protection against getting the virus. Coronavirus or COVID-19 can cause more severe symptoms and complications in people with diabetes, says Dan Howarth from Diabetes UK. If you have diabetes and you have symptoms such as a cough, high temperature and feeling short of breath you need to monitor your blood sugar closely and call the NHS 111 phone service.

People with diabetes who dont experience symptoms and have recently travelled to any of the affected areas need to follow information on the NHS and theGOV.UKwebsites, adds Howarth. "These are updated regularly and are the most up-to-date source of information available.

Its believed around 40 per cent of hospitalised coronavirus patients have heart disease. Somebody with a heart condition is more likely to have a compromised immune system, so their immune response wont be as strong if exposed to a virus. COVID-19 also targets the lungs, which could cause problems for a diseased heart that has to work harder to get oxygenated blood around the body.

Asthma is a respiratory condition that leads to inflammation of the breathing tubes that transport air to and from the lungs.Coronavirus can cause respiratory problems for anyone, but for the 5.4million people in the UK with asthma, the risk is greater, says Jessica Kirby, Head of Health Advice at Asthma UK. Respiratory viruses like thiscan triggerasthma symptoms and couldlead to anasthma attack.

Kirby says if youre a sufferer, itsessential to takeyour preventer, daily as prescribed. This helps cut the risk of an asthma attack being triggered by any virus, including coronavirus, she says. Keeping a reliever inhaler to handis vital, soyoucan use it ifyou get asthmasymptoms.

Ifyourasthma symptomsgetworse, and you havent travelled to an at-risk area or been in contact with someone who has, make an appointment to see your GP as soon as you can. If you think you might have coronavirus, use the NHS 111 online coronavirus service."

COPD is the name for certain lung conditions that cause breathing difficulties, including emphysema, which is characterised by damage to the air sacs in the lungs,and chronic bronchitis, which is a long-term condition involving inflammation of the lungs airways. People with COPD are more likely to get coronavirus if exposed to the virus because they have damage to their epithelial lining, which makes it easier for viruses to enter the body.

Cancer patients are more susceptible due to their compromised immune system. Various cancer drugs and treatments, like chemotherapy, mean your immune system may be suppressed, says Prof Chung, and this would increase your chances of catching it. And if you do get it while you havecancer, you would probably fare worse than somebody with the virus who didnt have cancer.

Not a health condition as such, but many of the thousands of deaths so far have involved elderly people with underlying health conditions. The elderly are at greater risk, and government advice for the elderly to avoid crowded areas is sound advice, says Prof Chung. The figures we have so far seem to imply the risk increases above the age of 70. However its even worse for those over 80. The chances of getting it and faring worse increase two or three times above the age the 70, but even more so above 80.

In terms of children, who appear to be less prone to getting the coronavirus and, if they do, getting a more benign version of the illness, Prof Chung says that a young person with an underlying health condition isn't at a greater risk: A young person with asthma, or heart disease, wouldnt be predisposed to get the coronavirusor suffer from it, in the same way an adult with the condition would, he says. Maybe its their immune system, and how its different from older people, but in terms of their susceptibility of getting the coronavirus, health conditions in young people dont seem to increase their chances of catching it.

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Evaluation of Factors Affecting the Severity of Diabetic Foot Ulcer in | DMSO – Dove Medical Press

Sunday, March 15th, 2020

Akram Ghobadi,1 Pegah Ahmadi Sarbarzeh,2 Milad Jalilian,2 Alireza Abdi,1 Sara Manouchehri3

1Nursing Department, Nursing and Midwifery School, Kermanshah University of Medical Sciences, Kermanshah, Iran; 2Nursing Department, Nursing and Midwifery School, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran; 3Biostatistics Department, Kermanshah University of Medical Sciences, Kermanshah, Iran

Correspondence: Pegah Ahmadi SarbarzehNursing Department, Nursing and Midwifery School, Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, IranTel +98 930 1946547Email Ahmadi.pegah554@yahoo.com

Introduction: Diabetes mellitus is a metabolic disease characterized by high blood sugar (BS) levels and the change in the metabolism of lipids, carbohydrates, and insulin resistance, and is one of the main causes of disability and mortality worldwide. Among the different types of complications, which have many negative effects on personal and social life, diabetic foot ulcer (DFU) is very important. This study aims to investigate the factors affecting the severity of DFU among patients with diabetes.Methods: The study participants included 190 diabetic patients with a diagnosis of DFU. Data were collected using a two-part questionnaire for self-care awareness and functions in diabetic patients and Wagners scale. The questionnaire was answered in cooperation with patients and the Wagners score was estimated bya wound supervisor in the diabetes center.Results: There was 109 women (57.4%). Twenty-six patients had other diabetic complications as well as DFU. The average score of awareness in patients was 6.99 2.76 and the function was 62.22 9.92. The results found a direct relation between the age and the durationofillness with the score of the patients awareness (P=0.008, P=0.000). There was also a direct relation between the level of education with score of awareness and the score of function in self-care (P=0.000, P=0.000), but the statistical results did not find any relation between awareness and the function in self-care of patients with the severity of DFU (P> 0.05).Discussion: There was no relation between the self-care awareness and function with severity of DFU (P> 0.05) that can be due to the more relation between DFU severity with hygiene and physical factors after the disease and the effect of awareness and function would be only in the incidence of the DFU.Conclusion: Awareness and function of patients in self-care is less than average. Increasing awareness of patients and empowering them through appropriate training can be effective in preventing diabetic foot ulcers.

Keywords: diabetes, diabetic foot ulcer, diabetes complications

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Chester woman won’t let diabetes get in the way of her first London Marathon – Cheshire Live

Sunday, March 15th, 2020

A woman from Chester is preparing to run her first marathon three years after being diagnosed with type 1 diabetes.

Kirsten Gooderham, 26, of Huntington, will take on the Virgin Money London Marathon on Sunday, April 26.

She is well on course to raise more than 2,000 in sponsorship for Diabetes UK, a charity which she says has transformed her life since her diagnosis in April 2017.

Type 1 diabetes causes the level of glucose in the blood to become too high. It happens when the body cant produce enough of a hormone called insulin, which controls blood glucose.

Type 1 diabetes is treated by daily insulin doses taken either by injections or via an insulin pump.

People with type 1 diabetes need to check their blood glucose levels are not too low or too high by using a glucose testing device several times a day.

Diabetes UKs Fight for Flash campaign empowered Kirsten to push for a flash glucose monitor. The device sits under the skin and measures the amount of sugar in the fluid under the skin, called interstitial fluid.

It has made it much easier for the former Chester Queens School pupil to manage her diabetes and run regularly in her free time.

Kirsten said: Flash means I no longer have to prick my fingers eight times a day in order to know my glucose readings. I can scan my arm and know within seconds what my levels are, 24/7.

Its changed my life completely and I have Diabetes UK to thank for that.

As well as reducing the need for as many finger pricks, the technology makes it easier to see when sugar levels are starting to rise or drop, meaning people can take action earlier.

Kirsten finds the monitor particularly useful when she is training and also uses an insulin pump, which she says is a massive help.

She added: Running is hard enough as it is, in terms of what to eat before a run, what to eat after. Now I have diabetes, its a constant battle of making sure Ive got enough carbs on board, and not having too many.

The main thing I found is you need to get into a routine to get out there and practice. Sometimes it goes wrong and you just have to move on and learn from it.

Sometimes it goes right, and its very rewarding when that happens.

Kirsten, who works as a production planner at a Deeside car engine factory, ran her first half-marathon while she was at university.

She had to pull out of the Chester Half Marathon in 2017 as it was due to take place soon after she was diagnosed with diabetes.

However, she managed to run it the following year and this year she will be stepping up to the full 26.2 miles in London for the first time.

The big run takes place three years and two days on from Kirstens diagnosis.

Clare Howarth, head of the North of England at Diabetes UK, said: Our much-needed work wouldnt be possible without the determination and generosity of our incredible fundraisers.

We are extremely grateful to Kirsten for her hard work running a marathon is no mean feat! The money raised will help fund ground-breaking research, care services and campaigns that can change the lives of those living with diabetes.

To sponsor Kirsten, please visit: https://justgiving.com/fundraising/Kirsten-Gooderham.

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What patients of diabetes, asthma need to do to stay safe from COVID-19 – ThePrint

Sunday, March 15th, 2020

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New Delhi: Coronavirus, which is now officially a pandemic, is deadly, but not for everyone. Illness due to coronavirus, also called COVID-19, is generally mild, especially for children and young adults, according to the World Health Organization (WHO).

However, the early clinical profile of COVID-19 suggests severe manifestation in people suffering from diabetes, cardiovascular conditions and lung diseases like asthma and chronic pulmonary obstructive disorder (COPD).

These conditions are common among Indians for example, India ranks second in diabetes incidence, with an estimated 7.7 crore diabetics, according to the International Diabetes Foundations Diabetes Atlas.

Similarly, medical journal The Lancet found heart diseases and strokes to be one of the top reasons for deaths in India, where the number of cardiovascular disease patients reportedly increased to 5.45 crore in 2016 from 2.57 crore in 1990.

COPD was the second-strongest cause of death in India after heart disease in 2017, killing 9.58 lakh Indians that year, according to the University of Washingtons Global Burden of Disease study 2018.

Patients of these conditions need to exercise additional caution amid the spread of COVID-19, which, according to WHO, had killed over 3,500 people by 8 March.

Such patients are primarily advised to stock drugs for the long-term and take extra precautions, and ensure theyve received vaccines for influenza and pneumococcal infections, which include severe pneumonia.

Also Read:Forget coronavirus, homoeopathy cant cure anything. Its a placebo, at best

While data about COVID-19 in patients with diabetes is limited at present, the condition was present in 42.3 per cent of 26 fatalities in Wuhan, China, the epicentre of the pandemic, according to a Chinese study (which factored in data for December 2019-January 2020) published by the Switzerland-based, peer-reviewed Journal of Clinical Medicine in February.

Individuals with diabetes are at risk of infections, especially influenza and pneumonia. This risk can be reduced, though not completely eliminated, by good glycaemic control. All people with diabetes (above 2 years of age) are recommended pneumococcal and annual influenza vaccinations, said Dr Anoop Misra, chairman at Fortis, C-Doc, in a study co-authored by him.

The research, titled Diabetes & Metabolic Syndrome: Clinical Research & Reviews, was published in the latest edition (May-June) of ScienceDirect, a portal for peer-reviewed research.

Pneumococcal vaccines prevent infections caused by bacteria spread through person-to-person contact, which could lead to serious infections like pneumonia, blood infections, and bacterial meningitis.

Patients with diabetes generally contract severe infections due to respiratory viruses.

Diabetes was seen as an important risk factor for mortality in patients infected with Pandemic Influenza A 2009 (H1N1), Severe Acute Respiratory Syndrome (SARS) coronavirus and Middle East Respiratory Syndrome-related coronavirus (MERS-CoV), the aforementioned study said.

When people with diabetes develop a viral infection, it is often difficult to treat them due to fluctuations in their blood glucose levels and the presence of diabetes complications. Their immune system is compromised, Dr Mahesh DM, a consultant for endocrinology at Bengalurus Aster CMI Hospital.

Also, patients with Type-1 diabetes should measure blood glucose and urinary ketones frequently if fever occurs while blood glucose levels are high.

Frequent changes in dosage may be required to maintain normal sugar in the blood, Misra said.

Also Read: 10 reasons why you dont need to panic about coronavirus

While the specific impact of coronavirus infection on the cardiovascular system remains unclear, according to the American College of Cardiology, there have been reports of acute cardiac injury, arrhythmias, hypotension, tachycardia, and a high proportion of concomitant cardiovascular disease in infected individuals, particularly those who require more intensive care.

Arrhythmia means irregular heartbeats while hypotension refers to abnormally low blood pressure and tachycardia to rapid heartbeats.

Patients who have undergone angioplasty or have a stent inside their hearts are believed to be more vulnerable to severe COVID-19 infection. The virus can cause tears in a patients blood vessels and then lead to secondary infections.

Influenza virus is already known as a propellant for heart attacks. The patients who are on blood-thinning medications, their chances of bleeding from lungs become high in case of coughing, such as in the case of coronavirus infection, said Yugal Kishore Mishra, head of cardiac sciences at Manipal Hospital in Delhi.

Based on an advisory from the US Centres for Disease Control and Prevention (CDC), doctors recommend that cardiac patients should take flu and bacterial pneumonia vaccinations.

When the body is fighting a major pathogen like coronavirus, it becomes vulnerable to other viruses and bacterial infections. The vaccine for flu and pneumonia will reduce the chances of death in case of coronavirus infections, said Dr K.K. Aggarwal, a cardiologist and former president of the Indian Medical Association (IMA).

Doctors also recommend immunity boosters along with a nutritious diet. I prescribe regular doses of Vitamin C and B-complex along with vaccination to the susceptible category, Mishra added.

Apart from stocking their routine medicines and inhalers, patients, experts advise, should consult doctors about new dosage requirements, if any.

With the summer coming, several patients re-adjust and reduce the dosage. In the winter, they generally need higher doses. This time, I recommend all patients to check with their doctors about the required dosage, said Dr Navneet Sood, pulmonology consultant at Dharamshila Narayana Superspeciality Hospital in Delhi.

We advise flu vaccines and pneumococcal vaccines apart from wearing N-95 masks, even if you are feeling healthy.

Also Read:Funny videos, TikTok dances, serious info how social media has responded to coronavirus

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Standardised self-management kits for children with type 1 diabetes: pragmatic randomised trial of effectiveness and cost-effectiveness. – DocWire…

Sunday, March 15th, 2020

This article was originally published here

Standardised self-management kits for children with type 1 diabetes: pragmatic randomised trial of effectiveness and cost-effectiveness.

BMJ Open. 2020 Mar 12;10(3):e032163

Authors: Noyes J, Allen D, Carter C, Edwards D, Edwards RT, Russell D, Russell IT, Spencer LH, Sylvestre Y, Whitaker R, Yeo ST, Gregory JW

AbstractOBJECTIVE: To estimate the effectiveness of standardised self-management kits for children with type 1 diabetes.DESIGN: Pragmatic trial with randomisation ratio of two intervention: one control. Qualitative process evaluation.SETTING: 11 diabetes clinics in England and Wales.PARTICIPANTS: Between February 2010 and August 2011, we validly randomised 308 children aged 6-18 years; 201 received the intervention.INTERVENTION: We designed kits to empower children to achieve glycaemic control, notably by recording blood glucose and titrating insulin. The comparator was usual treatment. OUTCOME MEASURES AT 3 AND 6 MONTHS: Primary: Diabetes Pediatric Quality of Life Inventory (PedsQL). Secondary: HbA1c; General PedsQL; EQ-5D; healthcare resource use.RESULTS: Of the five Diabetes PedsQL dimensions, Worry showed adjusted scores significantly favouring self-management kits at 3months (mean child-reported difference =+5.87; Standard error[SE]=2.19; 95% confidence interval [CI]) from +1.57to +10.18; p=0.008); but Treatment Adherence significantly favoured controls at 6months (mean child-reported difference=-4.68; SE=1.74; 95%CI from -8.10 to -1.25; p=0.008). Intervention children reported significantly worse changes between 3 and 6months on four of the five Diabetes PedsQL dimensions and on the total score (mean difference=-3.20; SE=1.33; 95%CI from -5.73 to -0.67; p=0.020). There was no evidence of change in HbA1c; only 18% of participants in each group achieved recommended levels at 6 months. No serious adverse reactions attributable to the intervention or its absence were reported.Use of kits was poor. Few children or parents associated blood glucose readings with better glycaemic control. The kits, costing 185, alienated many children and parents.CONCLUSIONS: Standardised kits showed no evidence of benefit, inhibited diabetes self-management and increased worry. Future research should study relationships between children and professionals, and seek new methods of helping children and parents to manage diabetes.TRIAL REGISTRATION NUMBER: ISRCTN17551624.

PMID: 32169923 [PubMed as supplied by publisher]

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Standardised self-management kits for children with type 1 diabetes: pragmatic randomised trial of effectiveness and cost-effectiveness. - DocWire...

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Why the UKs NHS leads the world in managing diabetes – Financial Times

Sunday, March 15th, 2020

While the UKs taxpayer-funded National Health Service suffers its share of criticism, its approach to the management and prevention of diabetes is widely recognised as world-leading.

Single-payer systems such as the NHS tend to perform well when it comes to the management of chronic diseases. In contrast to insurance-based provision, where people may move between providers every few years, compromising continuity of care, the NHS generally cares for its patients without interruption and free of charge for a lifetime.

This, in turn, creates the conditions in which a chronic disease such as diabetes can be effectively monitored and managed.

Jonathan Valabhji, a consultant diabetologist who combines his work as a doctor at Londons Imperial College Healthcare NHS Trust with his role as national clinical director for diabetes and obesity in NHS England, says the concept of free healthcare for all at the point of need is particularly well suited to chronic diseases, and in some respects diabetes is the classic chronic disease. Once you develop it, most people will have it for the rest of their lives.

The numbers underline the scale of the challenge facing the NHS. Statistics issued last month by NHS England show that almost 2m patients registered with a GP have non-diabetic hyperglycaemia, a condition which puts them at high risk of developing type-2 diabetes, the form of the disease linked to lifestyle.

Dr Valabhji says estimates suggest that about 10 per cent of the entire annual NHS budget is now being spent on people with diabetes. So it has a significant impact on the sustainability of the health system moving forward.

As a clinician, he is now diagnosing people at earlier and earlier ages. Since many of the complications that accompany diabetes, such as eye, kidney or foot disease, increase in prevalence the longer someone has the condition, this in turn has a big potential impact within the health service in the decades to come, he points out.

FT correspondents unearth the ways cities are helping their citizens live healthier lives, from doctors who prescribe exercise rather than pills, to a car-free economy that is booming. Listen to the series

To tackle this seemingly unrelenting tide of current and prospective cases, the NHS has worked to incentivise doctors to focus on treating the condition.

Since 2003 about 15 per cent of GP income has been related to delivering specific aspects of care. Of that, a significant proportion is focused on diabetes care, Dr Valabhji says, which I think has had an important impact on the quality of care across the country.

At the same time the NHS established a national diabetes audit, to track the effectiveness of care of patients, not only with type-2 diabetes, but also with type-1, an autoimmune disease that is not susceptible to lifestyle changes.

Perhaps its most far-reaching initiative is a national diabetes prevention programme that is the biggest of its type in the world and to which more than half a million people have been referred since it was established in 2014. By 2023-24 up to 200,000 people a year are expected to participate.

One of the innovative approaches that the NHS has adopted reflects recent evidence that limiting peoples dietary intake to just over 800 calories a day for three months can cause significant weight loss. Strikingly, in the case of people recently diagnosed with type-2 diabetes, the condition can actually be put into remission.

The NHS has also been at the forefront of exploring digital interventions to help overweight or obese people lose weight in order to prevent type-2 diabetes or to lessen the impact in those already diagnosed with the condition.

Among those whose innovations have been taken up the by NHS are Chris Edson and Mike Gibbs, two young engineers who set up a company called Second Nature. It uses a blend of technology such as smart weighing scales linked to an online app and professional and peer support to help people make the lifestyle changes that can ward off diabetes.

Second Nature has recently been accepted as a national provider for the diabetes prevention programme. Crediting the NHSs forward-thinking approach, Mr Edson says: There arent many health organisations in the world that have put their neck out and said, yes, we believe that digital has the outcomes for diabetes prevention and management and were going to commission it nationally.

His companys clients, he says, are people in the risk zone for diabetes. Our programme is to get them out of the risk zone. Separately it also offers a programme aimed at putting people who already have diabetes into remission.

We help them make such drastic lifestyle changes that they actually [no longer meet] the diagnostic criteria for type-2 diabetes and they come off all of their medication, he says. Data it has recently published in a professional journal show that it has achieved this feat in 40 per cent of cases, he adds.

Within five years, wed like to eradicate type-2 diabetes within the UK

About 5,000 NHS patients have already gone through the programme, for which people can also choose to pay themselves without a doctors referral.

Mr Edson has a striking ambition for Second Nature, which recently raised $10m in a venture capital funding round: Within five years, wed like to eradicate type-2 diabetes within the UK. Combined with other initiatives that the NHS is doing, I think its a realistic goal.

Meanwhile Dr Valabhji is awaiting data on the impact of the national diabetes prevention programme nationally, confident that it will show a reduction in the rate of growth in diabetes cases in England.

Results so far are extremely encouraging and I think it will be around 2021 that were able to show an impact on the trajectory of type-2 diabetes incidence, he says.

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Why the UKs NHS leads the world in managing diabetes - Financial Times

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