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Archive for the ‘Blindness’ Category

Portsmouth Daily Times | Prevent Blindness declares February as … – Portsmouth Daily Times

Monday, February 6th, 2017

Today, more than 2 million Americans ages 50 and over have age-related macular degeneration (AMD), according to the Prevent Blindness report, Future of Vision: Forecasting the Prevalence and Costs of Vision Problems. This includes 88,546 in Ohio alone. And, the increase of the population aged 80 and older will lead to rapid growth in the AMD population over the next 20 years, reaching 3.4 million in 2032 and 4.4 million by 2050.

The Ohio Affiliate of Prevent Blindness has declared February as Age-related Macular Degeneration/Low Vision Awareness Month. AMD is a leading cause of vision loss for Americans age 50 and older. It affects central vision, where sharpest vision occurs. Almost 3 million Americans have low vision, according to the National Eye Institute.

According to the recent National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division (NASEM) consensus study, Making Eye Health a Population Health Imperative: Vision for Tomorrow, increasing age, white race, and female gender are associated with a higher risk of AMD. The report also found that a number of environmental, behavioral, genetic, and other physical conditions have been associated with the risk of AMD, including smoking, obesity and genetics.

There may be no symptoms until the disease progresses or affects both eyes, which is why regular eye exams are important. Vision changes due to AMD may include:

Prevent Blindness offers educational materials at no cost through its dedicated web pages and its toll-free number. Resources include:

Prevent Blindness AMD Learning Center- The AMD Learning Center, found at preventblindness.org/amd, provides a variety of educational tools including AMD risk factors, treatment options, an Adult Vision Risk Assessment tool, fact sheets and more.

Living Well with Low Vision- This growing online resource, lowvision.preventblindness.org, offers information ranging from an extensive list of searchable, local low vision resource directories, to an informative blog with news for people living with age-related eye disease and significant visual impairment, and their caregivers, authored by patient advocate and low vision educator Dan Roberts, M.M.E.

By detecting AMD and treating it early, vision loss can be significantly lessened, said Sherry Williams, President & CEO of Prevent Blindness, Ohio Affiliate. We urge everyone to make an appointment for a dilated eye exam today.

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The dangers of AMD; disease can cause blindness if left untreated … – KHON2

Monday, February 6th, 2017

It strikes like a thief in the night.

The disease, if left untreated, can slowly steal your central vision, leaving you blind for the rest of your life.

Age-related macular degeneration (AMD) affects more than 10 million people in the U.S.

This is the most common cause of vision loss that is not correctable by lenses or cataract surgery, and is very common in the 80-plus group. Fifty percent of my patients have that disease, said ophthalmologist Dr. Malcolm Ing. That occurs at the back of the eye, right near the optic nerve, right where my finger is. That is the macular, and that is the area that deteriorates.

Patients may notice blacking or graying out at the central part of their vision while reading.

Patients with dry AMD receive antioxidants as treatment.Those with Wet AMD are at higher risk of going blind and must receive injections directly into the eyes every six weeks.

Its a downhill slide right away if you see hemorrhages in the macular, Ing said. If left untreated, you can go blind within a week.

One way to avoid this is to not smoke.

For instance, if you smoke, you have four times the incidents four times 400 percent increase in macular degeneration, Ing explained.

Controlling your weight also helps.

We found that you have a big opu, like some of the people have in our kupuna group, then you increase your incidents by 200 percent, so twice as likely to have that problem, Ing said.

Belly fat produces inflammatory chemicals that target our eyes and brain. Eating fish can reduce risk of AMD by 40 percent, and so can eating green leafy vegetables.

Eat your spinach, because it has green leafy vegetables, and green leafy vegetables has nutrients that help protect the retina, Ing said.

February is AMD Awareness Month, another reason to see your eye doctor regularly.

Click here for more information about AMD from the National Eye Institute.

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Heracleum mantegazzianum – Wikipedia

Wednesday, November 30th, 2016

Heracleum mantegazzianum, commonly known as giant hogweed,[1][2][3]cartwheel-flower,[1][2][3]giant cow parsnip,[4][5]hogsbane or giant cow parsley,[6] is a plant in the family Apiaceae. In New Zealand, it is also sometimes called wild parsnip,[2] or wild rhubarb.[2] It typically grows to heights of 25.5m (6ft 7in18ft 1in).[7] Superficially, it resembles common hogweed (Heracleum sphondylium), Heracleum sosnowskyi, or garden angelica (Angelica archangelica). It is phototoxic and considered to be a noxious weed in many jurisdictions. Giant hogweed is native to the Caucasus region and Central Asia. It was introduced to Britain as an ornamental plant in the 19th century, and it has also spread to many other parts of Europe, the United States, and Canada.

The sap of giant hogweed causes phytophotodermatitis in humans, resulting in blisters and long-lasting scars. These serious reactions are due to the furocoumarin derivatives in the leaves, roots, stems, flowers, and seeds of the plant.

Giant hogweed has a stout, bright green stem that is frequently spotted with dark red and hollow red-spotted leaf stalks that produce sturdy bristles. The stems grow to more than 2 m high.[8] The hollow stems vary from 38cm (1.23.1in) in diameter, occasionally up to 10cm (3.9in). Each dark red spot on the stem surrounds a hair, and large, coarse white hairs occur at the base of the leaf stalk. The plant has deeply incised compound leaves which grow up to 11.7m (3ft 3in5ft 7in) in width.

Giant hogweed is a biennial or monocarpic perennial,[7]:827 the plants usually begin dying after they have set seed. It usually flowers in its second year from late spring to midsummer, with numerous white flowers clustered in an umbrella-shaped head that is up to 80cm (31in) in diameter across its flat top. The plant produces 1,500 to 100,000 flattened, 1-centimetre (0.39in)-long, oval, dry seeds that have a broadly rounded base and broad marginal ridges. Tall dead stems may mark its locations during winter.

Giant hogweed was among many foreign plants introduced to Britain in the 19th century as ornamental plants. It is now widespread throughout the British Isles, especially along riverbanks. By forming dense stands, they can displace native plants and reduce wildlife habitats.[9] It has spread in the northeastern and northwestern United States, and southern Canada and is an invasive species in Germany, France, and Belgium, overtaking the local native species, Heracleum sphondylium.[9]

In Canada, the plant has been sighted in British Columbia, Alberta, Saskatchewan, Ontario, Quebec, New Brunswick, Nova Scotia, and in isolated areas of Newfoundland. It has been seen in Quebec since the early 1990s.[10] The plant's spread in Ontario began in the southwest and was seen in 2010 in the greater Toronto area and Renfrew County near Ottawa.[11]

Giant hogweed was introduced into New York about 1917, and was recorded in British Columbia in the 1930s. It now occurs in the west in British Columbia, Washington, and Oregon and in eastern North America from Newfoundland and Nova Scotia west to Ontario and Wisconsin and south to Indiana, Maryland, and New Jersey.[12][13] It is also recorded occasionally in Michigan[14] It is a federally listed noxious weed in many states.[12]

The sap of the giant hogweed plant is phototoxic; when the contacted skin is exposed to sunlight or to ultraviolet rays, it can cause phytophotodermatitis (severe skin inflammations). Initially, the skin colours red and starts itching. Blisters form as it burns within 48 hours. They form black or purplish scars that can last several years. Hospitalisation may be necessary.[9] Although many media reports on giant hogweed suggest the plant can lead to temporary or permanent blindness, existing research on the plant does not back up this claim.[15]

These reactions are caused by the presence of linear derivatives of furanocoumarin in its leaves, roots, stems, flowers, and seeds. These chemicals can get into the nucleus of the epithelial cells, forming a bond with the DNA, causing the cells to die. The brown colour is caused by the production of melanin by furocoumarins.

Authorities advise that children should be kept away from giant hogweed, that protective clothing, including eye protection, should be worn when handling or digging it, and that if skin is exposed, the affected area should be washed thoroughly with soap and water and the exposed skin protected from the sun for several days.[9]

Because of its phototoxicity and invasive nature, giant hogweed is often actively removed. In the UK, the Wildlife and Countryside Act 1981 makes it an offence to plant or cause giant hogweed to grow in the wild.[9][16] Hogweed is regulated as a federal noxious weed by the US government, and is illegal to import into the United States or move interstate without a permit from the Department of Agriculture.[17] The USDA Forest Service states pigs and cattle can eat it without apparent harm.[5] The New York State Department of Environmental Conservation has had an active program to control giant hogweed since 2008, including reporting, database maintenance, and crews for removal or herbicide control.[18][19] In 2011, Maine state horticulturists, describing the plant as "Queen Anne's lace on steroids", reported that it has been found at 21 different locations in Maine, with the number of plants ranging from one to a hundred.[20]

The 1971 album Nursery Cryme by the progressive rock group Genesis contains a song called "The Return of the Giant Hogweed". The lyrics describe a murderous attack on the human race by Heracleum mantegazzianum, long after the plant was first "captured" and brought to England by a Victorian explorer.[21] It is typical of the dramatic, tongue-in-cheek humour prevalent in the band's early recordings. A live version can be found on their 1973 Genesis Live album.

The 1971 studio recording appears in Series 1 Episode 1 ("And No Birds Sing") of the British TV crime drama Rosemary and Thyme as the episode story centres around hogweed.

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Blindness (Movie Tie-In) by Jos Saramago | 2900156035582 …

Tuesday, November 29th, 2016

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Winner of the 1998 Nobel Prize for Literature. A city is hit by an epidemic of 'white blindness.' The blindness spreads, sparing no one. Authorities confine the blind to a vacant mental hospital secured by armed guards. Inside, the criminal element among the blind hold the rest captive: food rations are stolen, women are raped. There is one eyewitness to this nightmare who guides seven strangers through the barren streets. The developments within this oddly anonymous group -- the first blind man, the old man with the black eye patch, the girl with dark glasses, the boy with no mother, and the dog of tears -- are as uncanny as the surrounding chaos is harrowing.

A parable of loss and disorientation, of man's worst appetities and hopeless weaknesses, Blindness is one of the most challenging, thought-provoking, and ultimately exhilarating novels published in any language in recent years.

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Blindness – Sensory Birth Defects – Medic8

Tuesday, November 29th, 2016

Birth defects affect the structure or function of parts or systems in the body and this can result in many different developmental and health problems. Birth defects which affect the sensory organs are known as sensory birth defects; the most common examples include cataracts, visual impairment, blindness and hearing loss.

Blindness rarely develops during the teenage and early adult years; most people are either born with blindness or develop it as a result of other visual problems which get worse as they age. In some rare cases, blindness may also result from an accident or injury or exposure to a harmful chemical. Blindness that exists from birth is known as congenital blindness; in this case, the baby will probably never be able to see. There are different degrees of visual impairment and some people who have a birth defect which affects the sensory organs only suffer from mild visual impairment.

There may be many different causes of congenital blindness and visual problems; possible causes are outlined below:

Blindness can also be caused by existing conditions, which become worse over time; examples of these conditions include glaucoma and cataracts, which may be common symptoms of birth defects.

Being blind does not have any impact on intellectual capacity but it may make learning more difficult because so much of our learning and development is aided by seeing the world around us. Blind children and adults tend to rely on their other senses, particularly their hearing and touch to guide them and enable them to learn. Using Braille and other tangible objects enables blind people to do everyday activities such as crossing the road, making a phone call or reading a book; Braille uses small tangible dots and bumps that can spell out words or replace letters or numbers. Audio books enable blind people to listen to books, rather than reading them and hearing can also be very beneficial for things like communicating with others and keeping safe when out and about.

Many children with visual impairment attend regular schools, although there are many specialist schools which cater for children with more severe visual problems and blindness. At school, pupils should be given additional support and the school should cater for them by providing Braille equipment and ensuring the surroundings are suitable and safe.

As mentioned above, many people rely on their other senses to get around and live a normal daily life; however, there are additional aids which can help to make life easier. Braille, as e have already established, is hugely beneficial for blind people; it allows them to do everything from making a telephone call and reading a book, to understanding forms and letters. Many blind people also benefit from having a specially trained guide dog; these dogs help to enable people to stay relatively independent and keep them safe when they are crossing roads or are out and about walking.

There is currently no cure for blindness and those born with blindness will have to face the reality of never being able to see; this is a strange, frightening concept for people who have good sight. There are treatments available for some visual conditions; however, not all problems are curable. If you are born with a visual impairment, your doctor or ophthalmologist will discuss all the possible options and treatment pathways with you.

Scientists and researchers are currently working on numerous projects to identify measures and treatments which can cure congenital blindness; one of the methods being trialled is gene therapy.

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Blindness Wikipdia

Thursday, November 24th, 2016

Un article de Wikipdia, l'encyclopdie libre.

Blindness, ou L'Aveuglement[1] au Qubec, est un film de science-fiction japono-canado-brsilien ralis par Fernando Meirelles, sorti en 2008.

Il s'agit de l'adaptation du roman Ensaio sobre a Cegueira (1995) de l'crivain portugais Jos Saramago, rcompens par le prix Nobel de littrature en 1998[2]. Le film est prsent en comptition officielle au festival de Cannes 2008[3].

Tout commence quand un homme perd subitement la vue alors quil est au volant de sa voiture, attendant que le feu passe au vert. Trs vite, chacune des personnes quil rencontre: le bon samaritain qui le raccompagne chez lui, son mdecin, les autres patients dans la salle d'attente sont frapps de ccit blanche. Seule la femme du mdecin est mystrieusement pargne. Alors que la contagion stend une vitesse fulgurante, la panique gagne la ville. Les victimes de lpidmie sont de plus en plus nombreuses et les autorits les placent en quarantaine dans un hpital dsaffect. La femme du mdecin, dcide rester auprs de son mari, fait croire qu'elle a galement perdu la vue. lhpital, elle tente dorganiser un semblant de vie quotidienne civilise. Lorsque le confinement dgnre en explosion de violence, elle prend la tte de la rvolte et guide une famille improvise travers la ville dvaste.

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Visual impairment – Wikipedia

Monday, October 31st, 2016

Visual impairment, also known as vision impairment or vision loss, is a decreased ability to see to a degree that causes problems not fixable by usual means, such as glasses.[1][2] Some also include those who have a decreased ability to see because they do not have access to glasses or contact lenses.[1] Visual impairment is often defined as a best corrected visual acuity of worse than either 20/40 or 20/60.[3] The term blindness is used for complete or nearly complete vision loss.[3] Visual impairment may cause people difficulties with normal daily activities such as driving, reading, socializing, and walking.[2]

The most common causes of visual impairment globally are uncorrected refractive errors (43%), cataracts (33%), and glaucoma (2%).[4] Refractive errors include near sighted, far sighted, presbyopia, and astigmatism.[4] Cataracts are the most common cause of blindness.[4] Other disorders that may cause visual problems include age related macular degeneration, diabetic retinopathy, corneal clouding, childhood blindness, and a number of infections.[5] Visual impairment can also be caused by problems in the brain due to stroke, prematurity, or trauma among others.[6] These cases are known as cortical visual impairment.[6] Screening for vision problems in children may improve future vision and educational achievement.[7] Screening adults without symptoms is of uncertain benefit.[8] Diagnosis is by an eye exam.[2]

The World Health Organization (WHO) estimates that 80% of visual impairment is either preventable or curable with treatment.[4] This includes cataracts, the infections river blindness and trachoma, glaucoma, diabetic retinopathy, uncorrected refractive errors, and some cases of childhood blindness.[9] Many people with significant visual impairment benefit from vision rehabilitation, changes in their environmental, and assistive devices.[2]

As of 2012 there were 285 million people who were visually impaired of which 246 million had low vision and 39 million were blind.[4] The majority of people with poor vision are in the developing world and are over the age of 50 years.[4] Rates of visual impairment have decreased since the 1990s.[4] Visual impairments have considerable economic costs both directly due to the cost of treatment and indirectly due to decreased ability to work.[10]

The definition of visual impairment is reduced vision not corrected by glasses or contact lenses. The World Health Organization uses the following classifications of visual impairment. When the vision in the better eye with best possible glasses correction is:

Blindness is defined by the World Health Organization as vision in a person's best eye with best correction of less than 20/500 or a visual field of less than 10 degrees.[3] This definition was set in 1972, and there is ongoing discussion as to whether it should be altered to officially include uncorrected refractive errors.[1]

Severely sight impaired

Sight impaired

Low vision

In the UK, the Certificate of Vision Impairment (CVI) is used to certify patients as severely sight impaired or sight impaired.[12] The accompanying guidance for clinical staff states: "The National Assistance Act 1948 states that a person can be certified as severely sight impaired if they are "so blind as to be unable to perform any work for which eye sight is essential". The test is whether a person cannot do any work for which eyesight is essential, not just his or her normal job or one particular job."[13]

In practice, the definition depends on individuals' visual acuity and the extent to which their field of vision is restricted. The Department of Health identifies three groups of people who may be classified as severely visually impaired.[13]

The Department of Health also state that a person is more likely to be classified as severely visually impaired if their eyesight has failed recently or if they are an older individual, both groups being perceived as less able to adapt to their vision loss.[13]

In the United States, any person with vision that cannot be corrected to better than 20/200 in the best eye, or who has 20 degrees (diameter) or less of visual field remaining, is considered legally blind or eligible for disability classification and possible inclusion in certain government sponsored programs.

In the United States, the terms partially sighted, low vision, legally blind and totally blind are used by schools, colleges, and other educational institutions to describe students with visual impairments.[14] They are defined as follows:

In 1934, the American Medical Association adopted the following definition of blindness:

Central visual acuity of 20/200 or less in the better eye with corrective glasses or central visual acuity of more than 20/200 if there is a visual field defect in which the peripheral field is contracted to such an extent that the widest diameter of the visual field subtends an angular distance no greater than 20 degrees in the better eye.[15]

The United States Congress included this definition as part of the Aid to the Blind program in the Social Security Act passed in 1935.[15][16] In 1972, the Aid to the Blind program and two others combined under Title XVI of the Social Security Act to form the Supplemental Security Income program[17] which states:

An individual shall be considered to be blind for purposes of this title if he has central visual acuity of 20/200 or less in the better eye with the use of a correcting lens. An eye which is accompanied by a limitation in the fields of vision such that the widest diameter of the visual field subtends an angle no greater than 20 degrees shall be considered for purposes of the first sentence of this subsection as having a central visual acuity of 20/200 or less. An individual shall also be considered to be blind for purposes of this title if he is blind as defined under a State plan approved under title X or XVI as in effect for October 1972 and received aid under such plan (on the basis of blindness) for December 1973, so long as he is continuously blind as so defined.[18]

Kuwait is one of many nations that share the 6/60 criteria for legal blindness.[19]

Visual impairments may take many forms and be of varying degrees. Visual acuity alone is not always a good predictor of the degree of problems a person may have. Someone with relatively good acuity (e.g., 20/40) can have difficulty with daily functioning, while someone with worse acuity (e.g., 20/200) may function reasonably well if their visual demands are not great.

The American Medical Association has estimated that the loss of one eye equals 25% impairment of the visual system and 24% impairment of the whole person;[20][21] total loss of vision in both eyes is considered to be 100% visual impairment and 85% impairment of the whole person.[20]

Some people who fall into this category can use their considerable residual vision their remaining sight to complete daily tasks without relying on alternative methods. The role of a low vision specialist (optometrist or ophthalmologist) is to maximize the functional level of a patient's vision by optical or non-optical means. Primarily, this is by use of magnification in the form of telescopic systems for distance vision and optical or electronic magnification for near tasks.

People with significantly reduced acuity may benefit from training conducted by individuals trained in the provision of technical aids. Low vision rehabilitation professionals, some of whom are connected to an agency for the blind, can provide advice on lighting and contrast to maximize remaining vision. These professionals also have access to non-visual aids, and can instruct patients in their uses.

The subjects making the most use of rehabilitation instruments, who lived alone, and preserved their own mobility and occupation were the least depressed, with the lowest risk of suicide and the highest level of social integration.

Those with worsening sight and the prognosis of eventual blindness are at comparatively high risk of suicide and thus may be in need of supportive services. These observations advocate the establishment and extension of therapeutic and preventative programs to include patients with impending and current severe visual impairment who do not qualify for services for the blind. Ophthalmologists should be made aware of these potential consequences and incorporate a place for mental health professionals in their treatment of these types of patients, with a view to preventing the onset of depressive symptomatology, avoiding self-destructive behavior, and improving the quality of life of these patients. Such intervention should occur in the early stages of diagnosis, particularly as many studies have demonstrated how rapid acceptance of the serious visual handicap has led to a better, more productive compliance with rehabilitation programs. Moreover, psychological distress has been reported (and is exemplified by our psychological autopsy study) to be at its highest when sight loss is not complete, but the prognosis is unfavorable.10 Therefore, early intervention is imperative for enabling successful psychological adjustment.[22]

Blindness can occur in combination with such conditions as intellectual disability, autism spectrum disorders, cerebral palsy, hearing impairments, and epilepsy.[23][24] Blindness in combination with hearing loss is known as deafblindness.

It has been estimated that over half of totally blind people have non-24-hour sleepwake disorder, a condition in which a person's circadian rhythm, normally slightly longer than 24 hours, is not entrained (re-set) to the light/dark cycle.[25][26]

The most common causes of visual impairment globally in 2010 were:

The most common causes of blindness in 2010 were:

About 90% of people who are visually impaired live in the developing world.[4] Age-related macular degeneration, glaucoma, and diabetic retinopathy are the leading causes of blindness in the developed world.[27]

Of these, cataract is responsible for >65%, or more than 22 million cases of blindness, and glaucoma is responsible for 6 million cases.

Cataracts: is the congenital and pediatric pathology that describes the greying or opacity of the crystalline lens, which is most commonly caused by intrauterine infections, metabolic disorders, and genetically transmitted syndromes.[28] Cataracts are the leading cause of child and adult blindness that doubles in prevalence with every ten years after the age of 40.[29] Consequently, today cataracts are more common among adults than in children.[28] That is, people face higher chances of developing cataracts as they age. Nonetheless, cataracts tend to have a greater financial and emotional toll upon children as they must undergo expensive diagnosis, long term rehabilitation, and visual assistance.[30] Also, according to the Saudi Journal for Health Sciences, sometimes patients experience irreversible amblyopia[28] after pediatric cataract surgery because the cataracts prevented the normal maturation of vision prior to operation.[31] Despite the great progress in treatment, cataracts remain a global problem in both economically developed and developing countries.[32] At present, with the variant outcomes as well as the unequal access to cataract surgery, the best way to reduce the risk of developing cataracts is to avoid smoking and extensive exposure to sun light (i.e. UV-B rays).[29]

Glaucoma is a congenital and pediatric eye disease characterized by increased pressure within the eye or intraocular pressure (IOP).[33] Glaucoma causes visual field loss as well as severs the optic nerve.[34] Early diagnosis and treatment of glaucoma in patients is imperative because glaucoma is triggered by non-specific levels of IOP.[34] Also, another challenge in accurately diagnosing glaucoma is that the disease has four etiologies: 1) inflammatory ocular hypertension syndrome (IOHS); 2) severe uveitic angle closure; 3) corticosteroid-induced; and 4) a heterogonous mechanism associated with structural change and chronic inflammation.[33] In addition, often pediatric glaucoma differs greatly in etiology and management from the glaucoma developed by adults.[35] Currently, the best sign of pediatric glaucoma is an IOP of 21mm Hg or greater present within a child.[35] One of the most common causes of pediatric glaucoma is cataract removal surgery, which leads to an incidence rate of about 12.2% among infants and 58.7% among 10-year-olds.[35]

Childhood blindness can be caused by conditions related to pregnancy, such as congenital rubella syndrome and retinopathy of prematurity. Leprosy and onchocerciasis each blind approximately 1 million individuals in the developing world.

The number of individuals blind from trachoma has decreased in the past 10 years from 6 million to 1.3 million, putting it in seventh place on the list of causes of blindness worldwide.

Central corneal ulceration is also a significant cause of monocular blindness worldwide, accounting for an estimated 850,000 cases of corneal blindness every year in the Indian subcontinent alone. As a result, corneal scarring from all causes is now the fourth greatest cause of global blindness.[36]

Eye injuries, most often occurring in people under 30, are the leading cause of monocular blindness (vision loss in one eye) throughout the United States. Injuries and cataracts affect the eye itself, while abnormalities such as optic nerve hypoplasia affect the nerve bundle that sends signals from the eye to the back of the brain, which can lead to decreased visual acuity.

Cortical blindness results from injuries to the occipital lobe of the brain that prevent the brain from correctly receiving or interpreting signals from the optic nerve. Symptoms of cortical blindness vary greatly across individuals and may be more severe in periods of exhaustion or stress. It is common for people with cortical blindness to have poorer vision later in the day.

Blinding has been used as an act of vengeance and torture in some instances, to deprive a person of a major sense by which they can navigate or interact within the world, act fully independently, and be aware of events surrounding them. An example from the classical realm is Oedipus, who gouges out his own eyes after realizing that he fulfilled the awful prophecy spoken of him. Having crushed the Bulgarians, the Byzantine Emperor Basil II blinded as many as 15,000 prisoners taken in the battle, before releasing them.[37] Contemporary examples include the addition of methods such as acid throwing as a form of disfigurement.

People with albinism often have vision loss to the extent that many are legally blind, though few of them actually cannot see. Leber's congenital amaurosis can cause total blindness or severe sight loss from birth or early childhood.

Recent advances in mapping of the human genome have identified other genetic causes of low vision or blindness. One such example is Bardet-Biedl syndrome.

Rarely, blindness is caused by the intake of certain chemicals. A well-known example is methanol, which is only mildly toxic and minimally intoxicating, and breaks down into the substances formaldehyde and formic acid which in turn can cause blindness, an array of other health complications, and death.[38] When competing with ethanol for metabolism, ethanol is metabolized first, and the onset of toxicity is delayed. Methanol is commonly found in methylated spirits, denatured ethyl alcohol, to avoid paying taxes on selling ethanol intended for human consumption. Methylated spirits are sometimes used by alcoholics as a desperate and cheap substitute for regular ethanol alcoholic beverages.

It is important that people be examined by someone specializing in low vision care prior to other rehabilitation training to rule out potential medical or surgical correction for the problem and to establish a careful baseline refraction and prescription of both normal and low vision glasses and optical aids. Only a doctor is qualified to evaluate visual functioning of a compromised visual system effectively.[45] The American Medical Association provide an approach to evaluating visual loss as it affects an individual's ability to perform activities of daily living.[20]

Screening adults who have no symptoms is of uncertain benefit.[8]

The World Health Organization estimates that 80% of visual loss is either preventable or curable with treatment.[4] This includes cataracts, onchocerciasis, trachoma, glaucoma, diabetic retinopathy, uncorrected refractive errors, and some cases of childhood blindness.[9] The Center for Disease Control and Prevention estimates that half of blindness in the United States is preventable.[2]

Aside from medical help, various sources provide information, rehabilitation, education, and work and social integration.

Many people with serious visual impairments can travel independently, using a wide range of tools and techniques. Orientation and mobility specialists are professionals who are specifically trained to teach people with visual impairments how to travel safely, confidently, and independently in the home and the community. These professionals can also help blind people to practice travelling on specific routes which they may use often, such as the route from one's house to a convenience store. Becoming familiar with an environment or route can make it much easier for a blind person to navigate successfully.

Tools such as the white cane with a red tip the international symbol of blindness may also be used to improve mobility. A long cane is used to extend the user's range of touch sensation. It is usually swung in a low sweeping motion, across the intended path of travel, to detect obstacles. However, techniques for cane travel can vary depending on the user and/or the situation. Some visually impaired persons do not carry these kinds of canes, opting instead for the shorter, lighter identification (ID) cane. Still others require a support cane. The choice depends on the individual's vision, motivation, and other factors.

A small number of people employ guide dogs to assist in mobility. These dogs are trained to navigate around various obstacles, and to indicate when it becomes necessary to go up or down a step. However, the helpfulness of guide dogs is limited by the inability of dogs to understand complex directions. The human half of the guide dog team does the directing, based upon skills acquired through previous mobility training. In this sense, the handler might be likened to an aircraft's navigator, who must know how to get from one place to another, and the dog to the pilot, who gets them there safely.

GPS devices can also be used as a mobility aid. Such software can assist blind people with orientation and navigation, but it is not a replacement for traditional mobility tools such as white canes and guide dogs.

Some blind people are skilled at echolocating silent objects simply by producing mouth clicks and listening to the returning echoes. It has been shown that blind echolocation experts use what is normally the "visual" part of their brain to process the echoes.[46][47]

Government actions are sometimes taken to make public places more accessible to blind people. Public transportation is freely available to the blind in many cities. Tactile paving and audible traffic signals can make it easier and safer for visually impaired pedestrians to cross streets. In addition to making rules about who can and cannot use a cane, some governments mandate the right-of-way be given to users of white canes or guide dogs.

Most visually impaired people who are not totally blind read print, either of a regular size or enlarged by magnification devices. Many also read large-print, which is easier for them to read without such devices. A variety of magnifying glasses, some handheld, and some on desktops, can make reading easier for them.

Others read Braille (or the infrequently used Moon type), or rely on talking books and readers or reading machines, which convert printed text to speech or Braille. They use computers with special hardware such as scanners and refreshable Braille displays as well as software written specifically for the blind, such as optical character recognition applications and screen readers.

Some people access these materials through agencies for the blind, such as the National Library Service for the Blind and Physically Handicapped in the United States, the National Library for the Blind or the RNIB in the United Kingdom.

Closed-circuit televisions, equipment that enlarges and contrasts textual items, are a more high-tech alternative to traditional magnification devices.

There are also over 100 radio reading services throughout the world that provide people with vision impairments with readings from periodicals over the radio. The International Association of Audio Information Services provides links to all of these organizations.

Access technology such as screen readers, screen magnifiers and refreshable Braille displays enable the blind to use mainstream computer applications and mobile phones. The availability of assistive technology is increasing, accompanied by concerted efforts to ensure the accessibility of information technology to all potential users, including the blind. Later versions of Microsoft Windows include an Accessibility Wizard & Magnifier for those with partial vision, and Microsoft Narrator, a simple screen reader. Linux distributions (as live CDs) for the blind include Oralux and Adriane Knoppix, the latter developed in part by Adriane Knopper who has a visual impairment. Mac OS also comes with a built-in screen reader, called VoiceOver.

The movement towards greater web accessibility is opening a far wider number of websites to adaptive technology, making the web a more inviting place for visually impaired surfers.

Experimental approaches in sensory substitution are beginning to provide access to arbitrary live views from a camera.

Modified visual output that includes large print and/or clear simple graphics can be of benefit to users with some residual vision.[48]

Blind people may use talking equipment such as thermometers, watches, clocks, scales, calculators, and compasses. They may also enlarge or mark dials on devices such as ovens and thermostats to make them usable. Other techniques used by blind people to assist them in daily activities include:

Most people, once they have been visually impaired for long enough, devise their own adaptive strategies in all areas of personal and professional management.

For the blind, there are books in braille, audio-books, and text-to-speech computer programs, machines and e-book readers. Low vision people can make use of these tools as well as large-print reading materials and e-book readers that provide large font sizes.

Computers are important tools of integration for the visually impaired person. They allow, using standard or specific programs, screen magnification and conversion of text into sound or touch (Braille line), and are useful for all levels of visual handicap. OCR scanners can, in conjunction with text-to-speech software, read the contents of books and documents aloud via computer. Vendors also build closed-circuit televisions that electronically magnify paper, and even change its contrast and color, for visually impaired users. For more information, consult Assistive technology.

In adults with low vision there is no conclusive evidence supporting one form of reading aid over another.[50] In several studies stand-based closed-circuit television and hand-held closed-circuit television allowed faster reading than optical aids.[50] While electronic aids may allow faster reading for individuals with low vision, portability, ease of use, and affordability must be considered for people.[50]

Children with low vision sometimes have reading delays, but do benefit from phonics-based beginning reading instruction methods. Engaging phonics instruction is multisensory, highly motivating, and hands-on. Typically students are first taught the most frequent sounds of the alphabet letters, especially the so-called short vowel sounds, then taught to blend sounds together with three-letter consonant-vowel-consonant words such as cat, red, sit, hot, sun. Hands-on (or kinesthetically appealing) VERY enlarged print materials such as those found in "The Big Collection of Phonics Flipbooks" by Lynn Gordon (Scholastic, 2010) are helpful for teaching word families and blending skills to beginning readers with low vision. Beginning reading instructional materials should focus primarily on the lower-case letters, not the capital letters (even though they are larger) because reading text requires familiarity (mostly) with lower-case letters. Phonics-based beginning reading should also be supplemented with phonemic awareness lessons, writing opportunities, and lots of read-alouds (literature read to children daily) to stimulate motivation, vocabulary development, concept development, and comprehension skill development. Many children with low vision can be successfully included in regular education environments. Parents may need to be vigilant to ensure that the school provides the teacher and students with appropriate low vision resources, for example technology in the classroom, classroom aide time, modified educational materials, and consultation assistance with low vision experts.

Communication with the visually impaired can be more difficult than communicating with someone who doesn't have vision loss. However, many people are uncomfortable with communicating with the blind, and this can cause communication barriers. One of the biggest obstacles in communicating with visually impaired individuals comes from face-to-face interactions.[51] There are many factors that can cause the sighted to become uncomfortable while communicating face to face. There are many non-verbal factors that hinder communication between the visually impaired and the sighted, more often than verbal factors do. These factors, which Rivka Bialistock[51] mentions in her article, include:

The blind person sends these signals or types of non-verbal communication without being aware that they are doing so. These factors can all affect the way an individual would feel about communicating with the visually impaired. This leaves the visually impaired feeling rejected and lonely.

In the article Towards better communication, from the interest point of view. Orskills of sight-glish for the blind and visually impaired, the author, Rivka Bialistock [51] comes up with a method to reduce individuals being uncomfortable with communicating with the visually impaired. This method is called blind-glish or sight-glish, which is a language for the blind, similar to English. For example, babies, who are not born and able to talk right away, communicate through sight-glish, simply seeing everything and communicating non-verbally. This comes naturally to sighted babies, and by teaching this same method to babies with a visual impairment can improve their ability to communicate better, from the very beginning.

To avoid the rejected feeling of the visually impaired, people need to treat the blind the same way they would treat anyone else, rather than treating them like they have a disability, and need special attention. People may feel that it is improper to, for example, tell their blind child to look at them when they are speaking. However, this contributes to the sight-glish method.[51] It is important to disregard any mental fears or uncomfortable feelings people have while communicating (verbally and non-verbally) face-to-face.

Individuals with a visual disability not only have to find ways to communicate effectively with the people around them, but their environment as well. The blind or visually impaired rely largely on their other senses such as hearing, touch, and smell in order to understand their surroundings.[52]

Sound is one of the most important senses that the blind or visually impaired use in order to locate objects in their surroundings. A form of echolocation is used, similarly to that of a bat.[53] Echolocation from a person's perspective is when the person uses sound waves generated from speech or other forms of noise such as cane tapping, which reflect off of objects and bounce back at the person giving them a rough idea of where the object is. This does not mean they can depict details based on sound but rather where objects are in order to interact, or avoid them. Increases in atmospheric pressure and humidity increase a person's ability to use sound to their advantage as wind or any form of background noise impairs it.[52]

Touch is also an important aspect of how blind or visually impaired people perceive the world. Touch gives immense amount of information in the persons immediate surrounding. Feeling anything with detail gives off information on shape, size, texture, temperature, and many other qualities. Touch also helps with communication; braille is a form of communication in which people use their fingers to feel elevated bumps on a surface and can understand what is meant to be interpreted.[54] There are some issues and limitations with touch as not all objects are accessible to feel, which makes it difficult to perceive the actual object. Another limiting factor is that the learning process of identifying objects with touch is much slower than identifying objects with sight. This is due to the fact the object needs to be approached and carefully felt until a rough idea can be constructed in the brain.[52]

Certain smells can be associated with specific areas and help a person with vision problems to remember a familiar area. This way there is a better chance of recognizing an areas layout in order to navigate themselves through. The same can be said for people as well. Some people have their own special odor that a person with a more trained sense of smell can pick up. A person with an impairment of their vision can use this to recognize people within their vicinity without them saying a word.[52]

Visual impairment can have profound effects on the development of infant and child communication. The language and social development of a child or infant can be very delayed by the inability to see the world around them.

Social development includes interactions with the people surrounding the infant in the beginning of its life. To a child with vision, a smile from a parent is the first symbol of recognition and communication, and is almost an instant factor of communication. For a visually impaired infant, recognition of a parent's voice will be noticed at approximately two months old, but a smile will only be evoked through touch between parent and baby. This primary form of communication is greatly delayed for the child and will prevent other forms of communication from developing. Social interactions are more complicated because subtle visual cues are missing and facial expressions from others are lost.

Due to delays in a child's communication development, they may appear to be disinterested in social activity with peers, non-communicative and un-education on how to communicate with other people. This may cause the child to be avoided by peers and consequently over protected by family members.

With sight, much of what is learned by a child is learned through imitation of others, where as a visually impaired child needs very planned instruction directed at the development of postponed imitation. A visually impaired infant may jabber and imitate words sooner than a sighted child, but may show delay when combining words to say themselves, the child may tend to initiate few questions and their use of adjectives is infrequent. Normally the child's sensory experiences are not readily coded into language and this may cause them to store phrases and sentences in their memory and repeat them out of context. The language of the blind child does not seem to mirror their developing knowledge of the world, but rather their knowledge of the language of others.

A visually impaired child may also be hesitant to explore the world around them due to fear of the unknown and also may be discouraged from exploration by overprotective family members. Without concrete experiences, the child is not able to develop meaningful concepts or the language to describe or think about them.[55]

Visual impairment has the ability to create consequences for health and well being. Visual impairment is increasing especially among older people. It is recognized that those individuals with visual impairment are likely to have limited access to information and healthcare facilities, and may not receive the best care possible because not all health care professionals are aware of specific needs related to vision.

The WHO estimates that in 2012 there were 285 million visually impaired people in the world, of which 246 million had low vision and 39 million were blind.[4]

Of those who are blind 90% live in the developing world.[56] Worldwide for each blind person, an average of 3.4 people have low vision, with country and regional variation ranging from 2.4 to 5.5.[57]

By age: Visual impairment is unequally distributed across age groups. More than 82% of all people who are blind are 50 years of age and older, although they represent only 19% of the world's population. Due to the expected number of years lived in blindness (blind years), childhood blindness remains a significant problem, with an estimated 1.4 million blind children below age 15.

By gender: Available studies consistently indicate that in every region of the world, and at all ages, females have a significantly higher risk of being visually impaired than males.

By geography: Visual impairment is not distributed uniformly throughout the world. More than 90% of the world's visually impaired live in developing countries.[57]

Since the estimates of the 1990s, new data based on the 2002 global population show a reduction in the number of people who are blind or visually impaired, and those who are blind from the effects of infectious diseases, but an increase in the number of people who are blind from conditions related to longer life spans.[57]

In 1987, it was estimated that 598,000 people in the United States met the legal definition of blindness.[58] Of this number, 58% were over the age of 65.[58] In 19941995, 1.3 million Americans reported legal blindness.[59]

To determine which people qualify for special assistance because of their visual disabilities, various governments have specific definitions for legal blindness.[60] In North America and most of Europe, legal blindness is defined as visual acuity (vision) of 20/200 (6/60) or less in the better eye with best correction possible. This means that a legally blind individual would have to stand 20 feet (6.1m) from an object to see itwith corrective lenseswith the same degree of clarity as a normally sighted person could from 200 feet (61m). In many areas, people with average acuity who nonetheless have a visual field of less than 20 degrees (the norm being 180 degrees) are also classified as being legally blind. Approximately ten percent of those deemed legally blind, by any measure, have no vision. The rest have some vision, from light perception alone to relatively good acuity. Low vision is sometimes used to describe visual acuities from 20/70 to 20/200.[61]

The Moche people of ancient Peru depicted the blind in their ceramics.[62]

In Greek myth, Tiresias was a prophet famous for his clairvoyance. According to one myth, he was blinded by the gods as punishment for revealing their secrets, while another holds that he was blinded as punishment after he saw Athena naked while she was bathing. In the Odyssey, the one-eyed Cyclops Polyphemus captures Odysseus, who blinds Polyphemus to escape. In Norse mythology, Loki tricks the blind god Hr into killing his brother Baldr, the god of happiness.

The New Testament contains numerous instances of Jesus performing miracles to heal the blind. According to the Gospels, Jesus healed the two blind men of Galilee, the blind man of Bethsaida, the blind man of Jericho and the man who was born blind.

The parable of the blind men and an elephant has crossed between many religious traditions and is part of Jain, Buddhist, Sufi and Hindu lore. In various versions of the tale, a group of blind men (or men in the dark) touch an elephant to learn what it is like. Each one feels a different part, but only one part, such as the side or the tusk. They then compare notes and learn that they are in complete disagreement.

"Three Blind Mice" is a medieval English nursery rhyme about three blind mice whose tails are cut off after chasing the farmer's wife. The work is explicitly incongruous, ending with the comment Did you ever see such a sight in your life, As three blind mice?

Poet John Milton, who went blind in mid-life, composed On His Blindness, a sonnet about coping with blindness. The work posits that [those] who best Bear [God]'s mild yoke, they serve him best.

The Dutch painter and engraver Rembrandt often depicted scenes from the apocryphal Book of Tobit, which tells the story of a blind patriarch who is healed by his son, Tobias, with the help of the archangel Raphael.[63]

Slaver-turned-abolitionist John Newton composed the hymn Amazing Grace about a wretch who "once was lost, but now am found, Was blind, but now I see." Blindness, in this sense, is used both metaphorically (to refer to someone who was ignorant but later became knowledgeable) and literally, as a reference to those healed in the Bible. In the later years of his life, Newton himself would go blind.

H. G. Wells' story "The Country of the Blind" explores what would happen if a sighted man found himself trapped in a country of blind people to emphasise society's attitude to blind people by turning the situation on its head.

Bob Dylan's anti-war song "Blowin' in the Wind" twice alludes to metaphorical blindness: How many times can a man turn his head // and pretend that he just doesn't see... How many times must a man look up // Before he can see the sky?

Contemporary fiction contains numerous well-known blind characters. Some of these characters can "see" by means of fictitious devices, such as the Marvel Comics superhero Daredevil, who can "see" via his super-human hearing acuity, or Star Trek's Geordi La Forge, who can see with the aid of a VISOR, a fictitious device that transmits optical signals to his brain.

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American Psychological Association (APA)

Saturday, October 29th, 2016

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Psychology's superhero

What's psychology's connection to Wonder Woman, the first feminist crusader?

Eating disorders

Learn about the major kinds of eating disorders and how a psychologist can help.

The discipline gap

Black students feel less welcome at schools with excessive suspensions, study finds.

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The only cure for OCD is expensive, elusive, and scary

October 27, 2016, The Atlantic

Autism study shows benefits when parents get involved

October 26, 2016, CNN

7 ways to know if you're on the right career path

October 25, 2016, Forbes

Teen hackers study considers link to addiction

October 24, 2016, BBC News

Can mental illness be prevented in the womb?

October 22, 2016, NPR

Talking to your therapist about election anxiety

October 20, 2016, The New York Times

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Blindness by Jose Saramago – Powell’s Books

Sunday, October 9th, 2016

Awards

Winner of the 1998 Nobel Prize for Literature A New York Times Notable Book of the Year A Los Angeles Times Best Book of the Year

A devastating and often horrific look at societal breakdown, Blindness is one of the most acclaimed novels from Jos Saramago, Portugal's only Nobel laureate for literature. Far more than a mere dystopian plague novel, Blindness is a metaphorical account of society's basest tendencies in the face of catastrophe. Saramago's magnificently wending sentences and trademark style lend grace and beauty to an otherwise gruesome tale of epidemic chaos. Recommended By Jeremy G., Powells.com

A city is hit by an epidemic of "white blindness" which spares no one. Authorities confine the blind to an empty mental hospital, but there the criminal element holds everyone captive, stealing food rations and raping women. There is one eyewitness to this nightmare who guides seven strangers among them a boy with no mother, a girl with dark glasses, a dog of tears through the barren streets, and the procession becomes as uncanny as the surroundings are harrowing. A magnificent parable of loss and disorientation and a vivid evocation of the horrors of the twentieth century, Blindness has swept the reading public with its powerful portrayal of man's worst appetites and weaknesses and man's ultimately exhilarating spirit. The stunningly powerful novel of man's will to survive against all odds, by the winner of the 1998 Nobel Prize for Literature.

"Beautifully written in a concise, haunting prose...this unsettling, highly original work is essential reading." Library Journal

"Saramago's Blindness is the best novel I've read since Gabriel Garcia Marquez' Love in the Time of Cholera. It is a novel of enormous skill and authority....Like all great books it is simultaneously contemporary and timeless, and ambitiously confronts the human condition without a false note struck anywhere. Saramago is one of the great writers of our time, and Blindness, ironically is the product of his extraordinary vision." David Guterson, author of Snow Falling on Cedars

"Blindness may be as revolutionary in its own way and time as were, say, The Trial and The Plague were in theirs. Another masterpiece." Kirkus Reviews, starred review

"Saramago writes phantasmagoria in the midst of the most astonishing fantasy he has a meticulous sense of detail. It's very eloquent stuff." Harold Bloom, author of The Western Canon

"It is the voice of Blindness that gives it its charm. By turns ironic, humorous and frank, there is a kind of wink of humor between author and reader that is perfectly imbued with fury at the excesses of the current century. Blindness reminds me of Kafka roaring with laughter as he read his stories to his friends....Blindness' impact carries the force of an author whose sensibility is significant." The Washington Post

"Blindness is a shattering work by a literary master." The Boston Globe

"More frightening than Stephen King, as unrelenting as a bad dream, Jos Saramago's Blindness politely rubs our faces in apocalypse....A metaphor like 'white blindness' might easily seem forced or labored, but Saramago makes it live by focusing on the stubbornly literal; his account of a clump of newly blind people trying to find their way to food or to the bathroom provides some surprisingly gripping passages. While this epidemic has a clear symbolic burden, it's also a real and very inconvenient affliction." Salon

In Blindness, a city is overcome by an epidemic of blindness that spares only one woman. She becomes a guide for a group of seven strangers and serves as the eyes and ears for the reader in this profound parable of loss and disorientation. We return to the city years later in Saramagos Seeing, a satirical commentary on government in general and democracy in particular. Together here for the first time, this beautiful edition will be a welcome addition to the library of any Saramago fan.

Jos Saramago (1922-2010) was the author of many novels, among them Blindness, All the Names, Baltasarand Blimunda, and The Year of the Death of Ricardo Reis. In 1998 he was awarded the Nobel Prize for Literature.

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Color Blindness – Topic Overview – WebMD

Sunday, September 11th, 2016

Color blindness means that you have trouble seeing red, green, or blue or a mix of these colors. It's rare that a person sees no color at all.

Color blindness is also called a color vision problem.

A color vision problem can change your life. It may make it harder to learn and read, and you may not be able to have certain careers. But children and adults with color vision problems can learn to make up for their problems seeing color.

Most color vision problems are inherited (genetic) and are present at birth.

People usually have three types of cone cells in the eye. Each type senses either red, green, or blue light. You see color when your cone cells sense different amounts of these three basic colors. The highest concentration of cone cells are found in the macula, which is the central part of the retina .

Inherited color blindness happens when you don't have one of these types of cone cells or they don't work right. You may not see one of these three basic colors, or you may see a different shade of that color or a different color. This type of color vision problem doesn't change over time.

A color vision problem isn't always inherited. In some cases, a person can have an acquired color vision problem. This can be caused by:

The symptoms of color vision problems vary:

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Optical Illusions and Visual Phenomena – Bach

Thursday, August 4th, 2016

are fascinating! They also teach us about our visual perception, and its limitations. Emphasis here is on beauty, interactive experiments, and attempts at explanation of the visual mechanisms involved.

Dont let it irk you if you dont see all the phenomena described. For many illusions, there is a percentage of people with perfectly normal vision who just dont see it, often for reasons currently unknown.

If you are not a vision scientist, you might find my explanatory attempts too highbrow. That is not on purpose, but vision research is not trivial, like any science. So, if the explanation seems gibberish, simply enjoy the phenomenon ;). More: Bach & Poloschek (2006) OpticalIllusionsPrimer; on the programming: Bach (2014, PDF).

Optical illusion sounds pejorative, as if exposing a malfunction of the visual system. Rather, I view these phenomena as highlighting particular good adaptations of our visual system to experience with standard viewing situations. These experiences are based on normal visual experiences, and thus under unusual contexts can lead to inappropriate interpretations of a visual scene (=Bayesian interpretation of perception).

Before we delve in, Id like to express my thanks for your @feedback ; any advice is appreciated .

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Editas CEO Katrine Bosley Predicts First CRISPR Human …

Thursday, August 4th, 2016

A biotechnology company says it will test advanced gene-engineering methods to treat blindness.

Editas CEO Katrine Bosley

The biotechnology startup Editas Medicine intends to begin tests of a powerful new form of gene repair in humans within two years.

Speaking this week at the EmTech conference in Cambridge, Massachusetts, Editas CEO Katrine Bosley said the company hopes to start a clinical trial in 2017 to treat a rare form of blindness using CRISPR, a groundbreaking gene-editing technology.

If Editass plans move forward, the study would likely be the first to use CRISPR to edit the DNA of a person.

CRISPR technology was invented just three years ago but is so precise and cheap to use it has quickly spread through biology laboratories. Already, scientists have used it to generate genetically engineered monkeys, and the technique has stirred debate over whether modified humans are next (see Engineering the Perfect Baby).

Editas is one of several startups, including Intellia Therapeutics and CRISPR Therapeutics, that have plans to use the technique to correct DNA disorders that affect children and adults. Bosley said that because CRISPR can repair broken genes it holds promise for treating several thousand inherited disorders caused by gene mistakes, most of which, like Huntingtons disease and cystic fibrosis, have no cure.

Editas, which had not previously given a timeline for an initial human test of CRISPR, will try to treat one form of a rare eye disease called Leber congenital amaurosis, which affects the light-receiving cells of the retina.

The condition Editas is targeting affects only about 600 people in the U.S., says Jean Bennet, director of advanced retinal and ocular therapeutics at the University of Pennsylvanias medical school. The target that they have selected is fantastic; it has all the right characteristics in terms of making a correction easily, says Bennett, who isnt involved in the Editas study.

Children with LCA are born seeing only large, bright shapes, and infants are diagnosed when they dont look into their mothers eyes or react to colorful balloons. Their poor vision can progress to stone cold blindness where everything is black, says Bennett.

Editas picked the disease in part because it is relatively easy to address with CRISPR, Bosley said. The exact gene error is known, and the eye is easy to reach with genetic treatments. It feels fast, but we are going at the pace science allows, she said. There are still questions about how well gene-editing will work in the retina and whether side effects could be caused by unintentional changes to DNA.

Editas plans to deliver the CRISPR technology as a gene therapy. The treatment will involve injecting into the retina a soup of viruses loaded with the DNA instructions needed to manufacture the components of CRISPR, including a protein that can cut a gene at a precise location. Bosley said in order to treat LCA, the company intends to delete about 1,000 DNA letters from a gene called CEP290 in a patients photoreceptor cells.

After the edit, preliminary lab experiments show, the gene should function correctly again. Bosley said Editas still needs to test the approach further in the lab and in animals before a human study starts.

Editas was created by venture capital funds including Third Rock Ventures in 2013 and was cofounded by scientists including Feng Zhang of the MIT/Harvard Broad Institute. It has raised more than $160 million in capital, allowing it to pursue ideas for several treatments simultaneously, Bosley said.

Although the Editas study could be the first for CRISPR in humans, it wouldnt be the first clinical study of gene editing. An older method called zinc fingers is already in testing to treat HIV infection by the biotechnology company Sangamo Biosciences. But the versatility and ease with which CRISPR can change DNA means it may outpace earlier approaches.

Theoretically, gene editing could be used to repair broken genes in any part of the body. But in practice it is difficult to make DNA repairs in most cell types, such as brain cells. The eye is an exception because doctors can inject treatment directly under the retina.

There is already a gene-therapy treatment for one form of LCA in late-stage clinical testing by Philadelphia biotech Spark Therapeutics, says Bennett, who helped develop that treatment. In that case, an entire, healthy version of a gene is being added to eye cells. Typically, gene therapy can only add genes, not edit them.

LCA has several different genetic causes, and standard gene therapy wont work for the form of the disease Editas is looking at. That is because the required gene, CEP290, is too big to fit inside a virus, says Bennett, and so there is no easy way to add it.

By targeting an exceptionally rare illness, Editas may have an easier time getting a treatment tested and approved. However, the eventual cost of such a treatment could be extraordinarily high, given the small number of people who would need it. Bennett says only around 3,000 Americans have LCA, and about 20 percent of those have the form being targeted by Editas.

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WHO | Measles

Thursday, August 4th, 2016

Key facts

Measles is a highly contagious, serious disease caused by a virus. In 1980, before widespread vaccination, measles caused an estimated 2.6 million deaths each year.

The disease remains one of the leading causes of death among young children globally, despite the availability of a safe and effective vaccine. Approximately 114900 people died from measles in 2014 mostly children under the age of 5.

Measles is caused by a virus in the paramyxovirus family and it is normally passed through direct contact and through the air. The virus infects the mucous membranes, then spreads throughout the body. Measles is a human disease and is not known to occur in animals.

Accelerated immunization activities have had a major impact on reducing measles deaths. During 2000-2014, measles vaccination prevented an estimated 17.1 million deaths. Global measles deaths have decreased by 79% from an estimated 546800 in 2000 to 114900 in 2014.

The first sign of measles is usually a high fever, which begins about 10 to 12 days after exposure to the virus, and lasts 4 to 7 days. A runny nose, a cough, red and watery eyes, and small white spots inside the cheeks can develop in the initial stage. After several days, a rash erupts, usually on the face and upper neck. Over about 3 days, the rash spreads, eventually reaching the hands and feet. The rash lasts for 5 to 6 days, and then fades. On average, the rash occurs 14 days after exposure to the virus (within a range of 7 to 18 days).

Most measles-related deaths are caused by complications associated with the disease. Complications are more common in children under the age of 5, or adults over the age of 20. The most serious complications include blindness, encephalitis (an infection that causes brain swelling), severe diarrhoea and related dehydration, ear infections, or severe respiratory infections such as pneumonia. Severe measles is more likely among poorly nourished young children, especially those with insufficient vitamin A, or whose immune systems have been weakened by HIV/AIDS or other diseases.

In populations with high levels of malnutrition and a lack of adequate health care, up to 10% of measles cases result in death. Women infected while pregnant are also at risk of severe complications and the pregnancy may end in miscarriage or preterm delivery. People who recover from measles are immune for the rest of their lives.

Unvaccinated young children are at highest risk of measles and its complications, including death. Unvaccinated pregnant women are also at risk. Any non-immune person (who has not been vaccinated or was vaccinated but did not develop immunity) can become infected.

Measles is still common in many developing countries particularly in parts of Africa and Asia. The overwhelming majority (more than 95%) of measles deaths occur in countries with low per capita incomes and weak health infrastructures.

Measles outbreaks can be particularly deadly in countries experiencing or recovering from a natural disaster or conflict. Damage to health infrastructure and health services interrupts routine immunization, and overcrowding in residential camps greatly increases the risk of infection.

The highly contagious virus is spread by coughing and sneezing, close personal contact or direct contact with infected nasal or throat secretions.

The virus remains active and contagious in the air or on infected surfaces for up to 2 hours. It can be transmitted by an infected person from 4 days prior to the onset of the rash to 4 days after the rash erupts.

Measles outbreaks can result in epidemics that cause many deaths, especially among young, malnourished children. In countries where measles has been largely eliminated, cases imported from other countries remain an important source of infection.

No specific antiviral treatment exists for measles virus.

Severe complications from measles can be avoided through supportive care that ensures good nutrition, adequate fluid intake and treatment of dehydration with WHO-recommended oral rehydration solution. This solution replaces fluids and other essential elements that are lost through diarrhoea or vomiting. Antibiotics should be prescribed to treat eye and ear infections, and pneumonia.

All children in developing countries diagnosed with measles should receive two doses of vitamin A supplements, given 24 hours apart. This treatment restores low vitamin A levels during measles that occur even in well-nourished children and can help prevent eye damage and blindness. Vitamin A supplements have been shown to reduce the number of deaths from measles by 50%.

Routine measles vaccination for children, combined with mass immunization campaigns in countries with high case and death rates, are key public health strategies to reduce global measles deaths. The measles vaccine has been in use for over 50 years. It is safe, effective and inexpensive. It costs approximately one US dollar to immunize a child against measles.

The measles vaccine is often incorporated with rubella and/or mumps vaccines in countries where these illnesses are problems. It is equally effective in the single or combined form. Adding rubella to measles vaccine increases the cost only slightly, and allows for shared delivery and administration costs.

In 2014, about 85% of the world's children received 1 dose of measles vaccine by their first birthday through routine health services up from 73% in 2000. Two doses of the vaccine are recommended to ensure immunity and prevent outbreaks, as about 15% of vaccinated children fail to develop immunity from the first dose.

In 2010, the World Health Assembly established 3 milestones towards the future eradication of measles to be achieved by 2015:

By 2014, the global push to improve vaccine coverage resulted in a 79% reduction in deaths. During 2000-2014, with support from the Measles & Rubella Initiative, measles vaccination prevented an estimated 17.1 million. During 2014, about 219 million children were vaccinated against measles during mass vaccination campaigns in 28 countries. All WHO Regions have now established goals to eliminate this preventable killer disease by 2020.

Launched in 2001, the Measles & Rubella Initiative (M&R Initiative) is a global partnership led by the American Red Cross, United Nations Foundation, Centers for Disease Control and Prevention (CDC), UNICEF and WHO. The M&R Initiative is committed to ensuring that no child dies from measles or is born with congenital rubella syndrome; reducing measles deaths by 95% by 2015; and achieving measles and rubella elimination in at least 5 WHO regions by 2020.

In 2012, the M&R Initiative launched a new Global Measles and Rubella Strategic Plan which covers the period 2012-2020.

The Plan provides clear strategies for country immunization managers, working with domestic and international partners, to achieve the 2015 and 2020 measles and rubella control and elimination goals.

Based on current trends of measles vaccination coverage and incidence, the WHO Strategic Advisory Group of Experts on Immunization (SAGE) concluded that the 2015 global milestones and measles elimination goals will not be achieved on time.

Measles is highly infectious and strong, sustained efforts are needed to maintain the current level of control. Improving coverage in the Democratic Republic of the Congo, Ethiopia, India and other high-burden countries will require changes in policies and practices that currently prevent vaccination of children 12 months of age or older.

To assess the reasons for the slowdown in progress since 2010 and to modify current strategies as needed, the Measles & Rubella Initiative partners have commissioned a mid-term strategy review.

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Blindness by Jos Saramago Reviews, Discussion …

Thursday, August 4th, 2016

From Nobel Prizewinning author Jos Saramago, a magnificent, mesmerizing parable of loss

A city is hit by an epidemic of "white blindness" that spares no one. Authorities confine the blind to an empty mental hospital, but there the criminal element holds everyone captive, stealing food rations and assaulting women. There is one eyewitness to this nightmare who guides her c

A city is hit by an epidemic of "white blindness" that spares no one. Authorities confine the blind to an empty mental hospital, but there the criminal element holds everyone captive, stealing food rations and assaulting women. There is one eyewitness to this nightmare who guides her chargesamong them a boy with no mother, a girl with dark glasses, a dog of tearsthrough the barren streets, and their procession becomes as uncanny as the surroundings are harrowing. As Blindness reclaims the age-old story of a plague, it evokes the vivid and trembling horrors of the twentieth century, leaving readers with a powerful vision of the human spirit that's bound both by weakness and exhilarating strength.

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Prevention of Blindness and Visual Impairment – WHO

Thursday, August 4th, 2016

The global eye health action plan 20142019 aims to reduce avoidable visual impairment as a global public health problem and to secure access to rehabilitation services for the visually impaired. This should be achieved by expanding current efforts by Member States, the WHO Secretariat and international partners, improved coordination, efficient monitoring, focusing the use of resources towards the most cost-effective interventions, and developing innovative approaches to prevent and cure eye diseases.

Blindness is the inability to see. The leading causes of chronic blindness include cataract, glaucoma, age-related macular degeneration, corneal opacities, diabetic retinopathy and eye conditions in children (e.g. caused by vitamin A deficiency). Age-related blindness is increasing throughout the world, as is blindness due to uncontrolled diabetes. On the other hand, blindness caused by infection is decreasing, as a result of public health action. Three-quarters of all blindness can be prevented or treated.

The magnitude of visual impairment and blindness and their causes have been estimated, globally and by WHO region from recent data. For countries without data estimates were based on newly developed model. Globally the number of people of all ages visually impaired is estimated to be 285 million, of whom 39 million are blind. People 50 years and older are 82% of all blind. The major causes of visual impairment are uncorrected refractive errors (43%) and cataract (33%); the first cause of blindness is cataract (51%). Visual impairment in 2010 is a major global health issue: the preventable causes are as high as 80% of the total global burden.

Visual impairment often limits peoples ability to perform everyday tasks and affects their quality of life. Blindness, the most severe form of visual impairment, reduces peoples ability to move about unaided unless properly trained.

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Blindness Synonyms, Blindness Antonyms | Thesaurus.com

Thursday, August 4th, 2016

We often, in our blindness, take a bit of our life, and look at it apart as an ended history.

It must be this sort of blindness which had led her so far in so fearful a delusion.

Therefore, let the choice be made in no haste and passion and blindness, but in deliberation and calm exercise of judgment.

Blindness is a 'privative', to be blind is to be in a state of privation, but is not a 'privative'.

Purblind men say, We do not see them, and mean, They are not; but all that their speech proves is their own blindness.

Similarly blindness is not said to be blindness of sight, but rather, privation of sight.

Before you were born, and after my blindness, I fancied that a change came over her.

This boon was granted; but the revelation which had come to him in blindness was not withdrawn.

Amid startled anguish his eyes suddenly opened to things he, in his blindness, had never guessed.

Nevertheless, no other explanation can be found for the blindness.

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What We Do | blindness.org

Thursday, August 4th, 2016

Mission Statement

The urgent mission of the Foundation Fighting Blindness is to drive the research that will provide preventions, treatments and cures for people affected by retinitis pigmentosa, macular degeneration, Usher syndrome, and the entire spectrum of retinal degenerative diseases.

Strategic Research Planning Report: A Summary

In keeping with its mission, and to ensure it has a focused and clinically relevant research program, the Foundation Fighting Blindness uses a strategic planning process to develop recommendations regarding long-term research goals. Held every four to five years, the most recent strategic planning meeting occurred in late 2008. A summary of the final outcomes from this effort and their implications for the next four to five years is presented here.

Since its founding in 1971, the Foundation Fighting Blindness has been dedicated to funding innovative research to find preventions, treatments, and cures for inherited retinal degenerative diseases that lead to blindness and affect more than 10 million people in the United States.

FFB currently funds over 134 research studies, 71 prominent research institutions and eye hospitals worldwide, including 15 dedicated research centers. In order to achieve our mission, we fund pioneering research in a comprehensive program that includes: cell biology, drug delivery, clinical & pre-clinical study, genetics, gene therapy, retinal cell transplantation, retinal implants and pharmaceutical and nutritional therapies.

In addition, FFB has established the Foundation Fighting Blindness Clinical Research Institute (FFB CRI) as a non-profit support subsidiary. FFB CRIs mission is to expedite the translation of fundamental research into clinical trials for inherited retinal degenerative diseases, and, ultimately to accelerate the availability of patient therapies. FFB CRI also fosters collaborations among the scientific, clinical, governmental, pharmaceutical, and financial communities.

Finally, FFBs mission includes public health education. We provide information on retinal degenerative diseases to all who request it, in order to increase knowledge and awareness of these diseases.

The Foundation Fighting Blindness is led by a governing board of up to 25 directors, who are elected by a board of national trustees numbering nearly 100.

FFB depends on its trustees and a nationwide volunteer fundraising network comprised of over 50 chapters to raise more than $33 million annually to fund its research initiatives. The organizations professional staff provides management and administrative support, both from our national office in Columbia, Maryland, and our eight regional offices located throughout the United States.

FOUNDATION FIGHTING BLINDNESS 7168 Columbia Gateway Drive, Suite 100 Columbia, MD 21046 PH: 1-800-683-5555

http://www.FightBlindness.org

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What We Do | blindness.org

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Blindness | Jewish Virtual Library

Thursday, August 4th, 2016

The standard Hebrew term for a blind person is (Heb. ) (ivver; Ex. 4:11; et al.), a noun in the form used for bodily defects. The abstract form is (ivvaron, "blindness"; Deut. 28:28; Zech. 12:4). The word (sanverim; Gen. 19:11; II Kings 6:18), sometimes incorrectly translated "blindness," means a blinding light causing (possibly temporary) loss of vision (E.A. Speiser). Eyes which cannot see are described by the verbs ("be dim"; Gen. 27:1; et al.), ("be fixed," "still"; I Sam. 4:15; I Kings 14:4), ("be darkened"; Lam. 5:17; et al.), ("be heavy"; Gen. 48:10), and and ("be smeared over;" Isa. 6:10, 32:3; 44:18; et al.). Genesis 29:17 describes Leah's eyes as rakkot, but whether this means "tender" or "weak" is moot.

Blindness was widespread in the ancient Near East. Preventive techniques included the application of hygienic ointments, especially kohl, and surgical operations (cf. The Code of Hammurapi, 21520 in Pritchard, Texts, 175). (There is no evidence that the biblical injunction against eating pork was intended or understood to prevent trichinosis or other diseases which cause blindness.) Biblical cases include Isaac (Gen. 27:1), Jacob (Gen. 48:10), Eli (I Sam. 3:2; 4:15), and Ahijah the Shilonite (I Kings 14:4), all of whose eyesight failed in old age. (Deut. 34:7 makes a point of reporting that Moses' eyesight had not failed in old age.) Both Isaac and Jacob in their blindness reversed the status of a younger and an older descendant in blessing them (Gen. 27 (cf. 29:236); 48:819).

Aside from old age, natural causes of blindness are not mentioned in the Bible. In a few passages blindness is mentioned as a punishment inflicted by God: it is threatened for Israel's violation of the covenant (Deut. 28:2829; M. Weinfeld takes this passage metaphorically; see below) and for the "negligent shepherd" of Zechariah 11:1517; Proverbs (30:17) warns that the eye which is disrespectful to parents will be plucked out by birds of prey (cf. The Code of Hammurapi, 193, in Pritchard, Texts, 175). Theologically speaking, all cases of blindness are attributed to God (Ex. 4:11), just as the restoration of sight is credited to Him (Ps. 146:8). However, outside of the specific cases mentioned, blindness in general is nowhere stated to be a punishment for sin. In a few passages God strikes His servants' assailants with blinding flashes (Gen. 19:11; II Kings 6:1820) or permanent blindness (Zech. 12:4; Ps. 69:24) in order to protect His servants.

As a punishment inflicted by human agency one finds the penalty of "an eye for an eye" in the talion formula (Ex. 21:24; Lev. 24:20; Deut. 19:21), although it is debated whether this was ever carried out literally in Israel (cf. The Code of Hammurapi, 1969, where the relation of the law to actual practice is similarly uncertain). Samson and King Zedekiah were blinded, respectively, by the Philistines and Nebuchadnezzar (Judg. 16:21; II Kings 25:7; Jer. 39:7; 52:11). Nahash the Ammonite demanded the putting out of the right eye of all the people of Jabesh-Gilead as a condition for sparing the city (I Sam. 11:2). Several passages speak of the eyes being "spent" or "pining away" from tears and grief. The verb used is usually ("Be spent"); the context makes it clear that soreness rather than blindness is meant (e.g., Lev. 26:16; Deut. 28:65; Jer. 14:6; Lam. 2:11; 4:17; cf. also , Ps. 6:8, "be spent," "waste away").

Blind persons are naturally helpless in many ways (cf. II Sam. 5:6; Isa. 35:56; Jer. 31:7, which invoke the blind, the lame, and the mute as representative examples of helplessness) and subject to exploitation (Deut. 28:29). Biblical ethics warned against exploiting them (Lev. 19:14; Deut. 27:18; Job 29:15).

As a physical defect blindness disqualified priests from sacrificing or approaching the altar (Lev. 21:1723) and rendered sacrificial animals unacceptable (Lev. 22:2122; Deut. 15:21; Mal. 1:8). Some have taken the enigmatic saying "the blind and the lame shall not come into the house" (II Sam. 5:8) to indicate that at one time these were forbidden entranceto temples.

Blindness is used with several metaphoric meanings in the Bible. Frequently it refers to the lack of intellectual or moral understanding (Isa. 29:910, 18). Judges are warned that bribes, or gifts, blind the eyes of the discerning (Ex. 23:8; Deut. 16:19). Isaiah is told that his mission is to besmear the eyes of Israel so that it will not "see" and repent and be healed (6:10). In Isaiah 56:10 blindness refers to negligence, while in Numbers 16:14 putting out the eyes is usually taken to mean deceiving. The

The Hebrew Braille system adopted universally in the 1950s.

helplessness and exploitability of the blind made blindness a natural metaphor for oppression and injustice in Deuteronomy 28:2829 and Isaiah 59:910 (cf. Lam. 4:14; M. Weinfeld has noted that the association of blindness and darkness with oppression in these passages also reflects the Mesopotamian association of the sun-god with justice (cf. a related association in II Sam. 23:34; Hos. 6:5b; Zeph. 3:5)). A related metaphor is the use of blindness to describe those who dwell in the darkness of prison or captivity (Isa. 42:7, 1619; 43:8; 49:9; 61:1; cf. Ps. 146:78; this use has roots in Mesopotamian royal inscriptions).

[Jeffrey Howard Tigay]

The unusually large number of talmudic sages who were blind probably reflects the wide prevalence of this disability in ancient times. In addition to Bava b. Buta, who was blinded by Herod (BB 4a), mention may be made of Nahum of Gimzo (Ta'an. 21a), Dosa b. Harkinas (Yev. 16a), and R. Joseph and R. Sheshet in Babylon (BK 87a), as well as a number of anonymous blind scholars (cf. ag. 5b; tj Pe'ah, end). Matya b. Heresh is said to have deliberately blinded himself to avoid temptation, but his sight was subsequently restored by the angel Raphael (Tan. B., ed. Buber, addition to xukkat). The talmudic name for a blind man is suma (ag. 1:1; Meg. 4:6), but the euphemism sagi nahor ("with excess of light") is often used (Ber. 58a.; TJ Pe'ah end; and especially Lev. R. 34:13 "the suma whom we call sagi nahor").

Unlike the deaf-mute, who is regarded in Jewish law as subnormal, the blind person is regarded as fully normal, and most of the legal and religious restrictions placed upon him are due to the limitations caused by his physical disability. The statement (Ned. 64b) based on Lamentations 3:6 "He hath made me to dwell in darkness as those that have been long dead" that "the blind man is regarded as dead," is of purely homiletic interest and has no practical application. In the second century R. Judah expressed the opinion that a blind man was exempt from all religious obligations, and as late as the time of the blind Babylonian amora Joseph (fourth century) the halakhah had not yet been determined (see his moving statement in bk 87a), but it was subsequently decided against his view. Even the statement of R. Judah that a person blind from birth cannot recite the Shema, since the first of the two introductory blessings is for the daily renewal of light (Meg. 4:6; TB Meg. 24a), was later amended since he enjoys the benefit of light (Rosh, resp. 4:21); the law that a blind man could not be called up to the reading of the Torah, since the passage must be read from the scroll (O 53:14), was abolished with the institution of the ba'al kore, who reads the passage for those called up (Taz. to O 141:1). The ruling of Jair ayyim Bacharach (avvot Ya'ir 176) that if there were a person more suitable, a blind person should not conduct the service is an individual opinion and Yehudai Gaon, who himself was blind, gives a contrary opinion (J. Mueller, Mafte'a li-Teshuvot ha-Ge'onim (1891), 67).

Similarly, although it was laid down that a totally blind person may not act as a judge, it is stated that when R. Johananheard of a blind man acting as judge he did not forbid it (Sanh. 34b, cf. M 7:2; for instances in the Middle Ages see Pahad Yiak S.V. Suma). Even as late as the time of Joseph Caro in the 16th century, it was laid down that a blind person is forbidden to act as a shoet only "in the first instance"; the total prohibition was enacted later (YD 1:9 and commentaries). A special case was the exemption of a blind person from the duty of going up to Jerusalem on the Pilgrim Festivals. The special nature of this law, which is derived from the homiletical interpretation of a word, is seen in the fact that it applied even to a person blind in only one eye (ag. 1:1, and TB ag. 2a).

During the Middle Ages, blinding was imposed by some battei din as a form of extrajudicial punishment and was condoned by contemporary rabbis (Assaf in bibl. nos. 97, 98, 135). Blindness was said to be caused by bloodletting at unfavorable times and by the machinations of demons (see Zimmels in bibl., pp. 88 and 153).

The question has been raised in recent times as to the permissibility of removing the cornea of a deceased person and grafting it on a blind person to restore his sight. Halakhic opinion is almost unanimously in favor, and in a responsum I.J. Unterman added the consideration that the danger to the life of a blind person through accidents is such that it can be regarded as a special case of pikku'a nefesh (see *Autopsy ).

[Louis Isaac Rabinowitz]

The Jewish blind have been traditionally assisted by regular communal and voluntary agencies and associations, as well as special institutions. In the United States the New York Guild for the Jewish Blind, founded around 1908, had a home for aged blind, has offered integrated services to the visually handicapped, and has initiated a nonsegregated living plan for the blind. In the United Kingdom the central agency was the Jewish Blind (now Jewish Blind and Disabled) Society in London, founded in 1819. By 1970 it was caring for the needs of over 1,500 Jewish blind. It maintained a number of residential and holiday facilities, day centers in provincial cities, and the Burr Center for Personal Development which offered various courses for the blind and disabled.

The special conditions in Israel as a country of immigration created the problem that the proportion of blind persons of working age in the state was three times higher than in Anglo-Saxon countries (1956). Much has been done to alleviate this position, while the blind person is as far as possible not treated as a social case. He is, however, exempted from paying income tax. Special placement officers facilitate his employment. In 1956 the proportion of blind to ordinary residents was estimated at approximately 2.5 per 1,000; 87% of them had immigrated after 1948. Over 85% were born in countries of Asia and Africa where in many cases the blind were not cared for or enabled to work. There was a comparatively high proportion of married women or widows due to marriage of blind girls to elderly men. The Jewish Institute for the Blind in Jerusalem, founded in 1902, cared for the majority of blind children in the country. It included a kindergarten, elementary school where subjects were taught in braille, and boarding facilities for 6090 pupils attending regular secondary school. It also had a vocational school, industrial training shop, a braille printing press, and two houses for mentally or physically handicapped blind adults.

Other agencies and associations for help of the blind in Israel included Migdal Or, the American Israeli Lighthouse Rehabilitation Center for the Blind in Haifa (Kiryat ayyim), which gave casework reorientation, special training and courses, and has developed home industries for blind who are physically incapacitated. The Women's League for Israel of New York assisted joint projects with the Ministry of Social Welfare for rehabilitation of blind girls and women, and maintained a sheltered workshop, Orah, and a bookbindery, Malben, which in 1951 took over Kefar Uriel, a village for the blind established in 1950 by the Jewish Agency for blind immigrants; in 1962 it had 63 families (about 350 persons). Heads of families were employed in four workshops. The Israel Foundation for Guide Dogs for the Blind in Haifa was established around 1950. A Central Library for the Blind, established in 1952 in Netanya, had over 5,000 volumes in braille and a talking book library.

The Association for the Blind and Prevention of Blindness, founded in 1953, had branches in nine centers. The National Council for the Blind, established in 1958 for coordinating, research, and planning, was represented on the World Council for the Blind. Voluntary agencies giving assistance from abroad include Hilfe fuer Blinde in Switzerland and Aide aux Aveugles Israliens in France. Training for non-Jewish blind has also been given by the Saint Vincent Roman Catholic hostel in Jerusalem, and at handicraft centers established in Nazareth and Shefaram. Isolated Arab villages have been visited by home teachers.

There is no statutory registration of blindness anywhere in the world. All comparative statistics on the incidence and causes of blindness are therefore largely speculative, and this applies in particular to statistics on blindness in Jews, for whom data are usually lacking in whatever national statistics are available. Comparative studies are thus impossible, and little more than some generalizations can be advanced.

The incidence and causes of blindness in most parts of the world are determined essentially by environmental factors. Jews, as a widely dispersed community, therefore suffer from the locally prevailing environmental causes of blindness. In this respect, if the incidence of blindness in a particular Jewish community is different from that in the general population, it will merely reflect the differences found in the various social groupings of the population at large. Thus it occurs in all countries where trachoma is endemic. The disease is more prevalent in rural areas, ill provided with sanitation and health services, than in the more developed urban centers with their populations relatively well housed and well served medically. The high incidence of trachoma in Oriental Jews who immigrated to Israel reflects country of origin and social level, rather than their Jewishness.

In the more highly developed countries, infections and other environmental causes of blindness are steadily declining, and most cases of blindness are now due to affections seen in the elderly (such as "senile" cataract and "senile" macular degeneration) or in the middle-aged (such as glaucoma and, to a lesser extent, myopic atrophy, uveitis, and diabetic retinopathy). These are all "constitutional" diseases, and clinical experience in Western Europe and the United States has brought out a greater incidence of three of these affections in Jews: myopia, diabetic retinopathy, and Tay-Sachs disease, a rare lethal disorder. Although adequate statistics are lacking, this clinical experience is probably well-founded and would be readily explained by the fact that these three affections are all genetically determined, generally by recessive or by polygenic inheritance. Although there is no such thing as a Jewish gene pool, it is true that inbred groups Quakers no less than Jews and royal families no less than village communities have many features and genes in common. These are readily perpetuated under the prevailing conditions: a recessive mutant gene is much more likely to spread in a closed community than elsewhere. (The gene for Tay-Sachs disease probably originated as such a mutant in a Jewish family in White Russia during the last century, and by emigration, carriers have spread it into the Jewish communities of Great Britain and the United States.) Contrary to early beliefs, the affection is not exclusively Jewish, for it is seen in other ethnic groups as well. These occasional cases do not add substantially to the instances of hereditary blindness in Jews, and it is a moot point whether the greater incidence of blindness from high myopia and diabetic retinopathy in Western Jews adds to that load. The numbers involved would be relatively slight, and compensating deficiencies in other hereditary causes are theoretically possible; actual data are lacking, however.

See section on Braille in *Alphabet, Hebrew .

[Arnold Sorsby]

Gordon, in: Archives of Ophthalmology, 9 (1933), 751ff.; E.A. Speiser, Genesis (1964), 139 (on Gen. 19:11); idem, in: JCS, 6 (1952), 81ff. (esp., 89 n. 52); Harrison, in: IDB, 1 (1962), 4489; M.Z. Segal, Sifrei Shemu'el (1964), 260, 262 (on II Sam. 5:6, 8); Weinfeld, in: Biblica, 46 (1965), 4201; Paul, in: JAOS, 88 (1968), 182; H.J. Zimmels, Magicians, Theologians and Doctors (1952), 461 notes; S. Assaf, Ha-Onshin Aarei atimat ha-Talmud (1922), 97 98, 135.

Source: Encyclopaedia Judaica. 2008 The Gale Group. All Rights Reserved.

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Blindness | ReverbNation

Thursday, August 4th, 2016

Right now alls I want is someone to plop a Mad Hatter chapeau on my noggin, dose me, point in the direction of the nearest clandestine warehouse gig, and play this fucker loud.

This record by Blindness is among the best of what the shoegaze/postpunk moment of this year has to offer. Words fail to describe the genius of this album, one that will end up in the list of 2015

Theres a lot more to this album than a cursory glance would catch... Imagine PJ Harvey fronting a band made up of the members of The Scientists, Rema Rema and Guided By Voices. Trust me, this one needs to to be heard.

... Wrapped in Plastic is not industrial. Its electronic infused rock, with enough melodies to give it some pop cred. However it is much too dirty, to slick to be defined by those terms. As the band describes it, its Electro Filth, and its awesome!

BLiNDNESS is a loud shoegaze-centric trio out of London who released debut album Wrapped In Plastic through Saint Marie Records. It's a sonic blast that comes from Debbie Smith of Curve and Echobelly, a dark shivering slithering beast of a record.

Blindness is an aggressive trio of noise mongers... Feedback aficionados take note this one will scrape the paint off your living room walls while its ferocious energy will have you pogoing around the room.... these are not your typical Girl On A Motorcycle, leatherclad dolly birds looking to get peeled, rather hard rocking veterans incorporating their varied influences into a darkly fascinating listening experience.

BLiNDNESS just feels like they're operating on a different plane than everyone else and I love it about them.

From the opening fuzz-laden, sleazy bass grind of the opening Serves Me Right to the closing dark, hazy, danceable psychedelia of Confessions, Wrapped In Plastic maintains a thoroughly engaging standard of excellence rarely heard at all, let alone on a first release... Its English 90s Britpop and shoegaze mastery updated for a modern age of self-exiled technocrats.

Serves Me Right, the latest track taken from Twin Peaks-referencing debut album Wrapped In Plastic, may well remind you of JAMCs Sidewalking in its glorious sleaziness.

It may have been a long time coming but the debut album from BLiNDNESS makes time immaterial as it sizzles on the senses from start to finish spreading a dark wave electro pop seduction which is just as likely to snarl and explode with attitude as it is to smoulder and caress. Wrapped In Plastic is a sonically and imaginatively charged incitement, an adrenaline driven helter-skelter of sound and energy that ears and thoughts quickly bask in. The accompanying press release to the album calls it a rollercoaster ride of beautiful chaos and that about says it all... Wrapped In Plastic (is) a release you need to spend time with to reap all its strengths and qualities. BLiNDNESS definitely rewards such focus though with an encounter which leaves ears ringing, bodies sweaty, and satisfaction bloated.

BLINDNESS 101: A BRIEF INTRO TO A TRIO YOU DESPERATELY NEED TO BE LISTENING TO Although the UKs BLiNDNESS technically formed in 2008, their debut full-length, WRAPPED iN PLASTiC, isnt set to hit shelves until July 24th although the album is well worth the wait BLiNDNESS is comprised of Beth Rettig, Emma Quick, and Debbie Smith (of Curve, Echobelly, and Snowpony fame), a trio whose sonic output is reflective of many of the 1990s greatest musical movements, from straight-ahead alt rock to shoegaze and electronic rock, with notable hints of industrial and grunge, but while always maintaining an aesthetic that puts their songwriting (which seems largely indebted to post-punk) center stage. The band...have an upcoming album launch show on July 26th at Londons Nambucca and, although they have no current plans to play this side of the Atlantic, in a recent chat with Beth Rettig, she reveals to me that thats something that (they) could get quite excited about...

Band of the Month - July - Blindness As the country bakes in current heat wave, we thought wed bring you one of the coolest bands to come out of scorching London, Blindness. The trio are set to release their fervently anticipated debut LP, which is already heralding critical acclaim and rightly so too. Two of the band, Beth Rettig and Debbie Smith, answer our questions...

Tracks of the Month (May 2015) Blindness - Sunday Morning from Wrapped In Plastic album. "The debut album from Blindness has been a long, long time coming, but having heard the whole thing a few times now (a review is nearly complete, I promise!), it delivers on the promise that this band have had for ages now. The pick of the album for me is this track, like a few on the album a long-time part of their live repertoire. Rather than the squalling guitar effects and bitter, furious vocals that are their perhaps more regular sound, this song has a more languid air that befits the title, a near trip-hop-esque beat and the fuzzy, remorseful feel of the morning after that follows a long, long night. The album Wrapped In Plastic is released 24-July."

THE MAGNIFICENT 7 Week 22 No. 5 Humming Song by BLINDNESS Multilayered, dark electro turmoil from London

Wrapped in Plastic wraps its smooth electro legs around you with an impulsive sexual ferocity. Like a mind blowing encounter with a mysterious woman you met a day ago that has to abruptly leave to catch her flight home. She obviously didn't tell you her secret and you're too caught up in the stranglehold-high to even care. Dark erotic melodies and grinding disco-dark waves drag you into a turbulent sea of lust, euphoria, and sultry contemplation on the latest full-length from the band known as BLiNDNESS. Hesitant sordid fragments of feedback and sonic six string scratches breathe heavy within these mood altering alterations of modern song. Kicking and playfully screaming from start to finish, the seductive and wary vocals of Beth Rettig pull you into the sweet ruptured noise. She hones a twisted tone that combines Sleeper and The Stranglers into a steamy design of volatile unhinged harmony... a feverish nine-song sleepwalk into the darkest pleasures of an endless summer night.

The trio of Beth Rettig, Emma Quick, and Debbie Smith (guitarist for Curve, Echobelly, and Snowpony) take the sideways-side-walking paths established by the UKs leather & distortion clad indie upstarts deeper into the melting pot marshes of melted & boiled media fabrics that informs todays rebels. The video for Confessions presents Beth, Debbie, and Emma performing about in a linen covered (or maybe its plastic?) space, where Blindness sheds some views into dealing with matters whilst feeling broke down. Without a sign of surrendering to fleeting feelings, and asserting themselves; Blindness takes on a slew of different expressive poses to show serious sides, the aches of being addled with anxiety, and more to make for dramatic shots to match the gruelling grate of guitar gears.

Featuring Beth Rettig (vocals, programming), Emma Quick (bass) and Debbie Smith (guitar), best known as being the guitarist in Curve, Echobelly and Snowpony, the London-based trio Blindness formed in 2008. And since the bands formation, theyve developed a reputation for a darkly seductive sound thats been influenced by The Jesus and Mary Chain, My Bloody Valentine and PJ Harvey. As youll hear on their latest single, Confessions off their forthcoming album, Wrapped in Plastic, the song consists of explosive blasts of propulsive drumming, power chords played through layers upon layers of distortion and feedback paired with Rettigs come hither vocals and as a result, the trio have received quite a bit of attention across their native London; but I suspect that with the release of Wrapped in Plastic, youll start hearing more about the British trio, as they put a subtle yet new spin on a familiar and beloved sound.

I first encountered London Blindness about 12 months ago and was blown away by their music... Their sound takes a walk on the darker side of chillwave with an electro-pop sheen. They recycle Garbage (sorry current resist) with more than a hint of one of guitarist Debbie Smith's former bands Curve. The awesome 'Broken' is a slab of dirty, sleazy, dark robotic pop. 'Confessions' is more Curvey with a beat so big it could cause an earthquake. There are none so blind than those that will not see the brilliance of Blindness.

...The music is spacious, urgent and dark with the last track reminiscent of how Joy Division would have sounded had PJ Harvey been at the Helm..

Thanks to a friend for the headsup on this lot - a seemingly London-based band who, by their own admission, channel Kate Bush, My Bloody Valentine, Curve and Nine Inch Nails, and remarkably really do end up sounding like a mashup of the four. It has a shoegazey vibe to it, particularly in the barely intelligible vocals, the buzzing guitars, and the dense production. But crucially they haven't forgotten the tunes, particularly in the fantastic title track. They are playing live in London twice this month, and I perhaps ought to make a beeline for at least one of the gigs - I suspect we are going to be hearing a lot more about this lot in the coming months.

A Model Of Control

...Fans of Curve MBV, Lush, NIN and the JAMC will no doubt be impressed by the throbbing beast of a song that is Confessions fusing loops, beats with searing guitar to devastating effect.

Tonight I only have time for one band. And I choose...Blindness. Blindness layer their songs in shuddering sheets of effect-laden guitar-noise, the sweeping guitar-tides break on the rocks of the beat. Programming and real drums, working together in an unholy alliance, slap down a rhythm that doesn't mess about. The basslines go striding relentlessly through the sonic surf as if they're wearing wading boots. There's a pop sensibility at work in the songwriting, too. The band don't just do noise. Vocalist Beth Rettig strikes surrealist vogueing shapes in a dress that looks like it's had a bite taken out of it by a passing shark (what is it with me and my sea similies today?) and sings in a glassy croon that goes from soothing to scary in the space of a chorus. As the set progresses, the scariness levels increase until she reaches some sort of overload and collapses on stage, lying there unmoving as the music convulses around her...

No messing around here, heavily Nine Inch Nails influenced electro-pop that is lean and polished. The thundering title track sounds like giant factory machinery that just happens to be creating music, howling and whistling with feedback, a constant for most of the EP that never sounds gratuitous. Confessions is a fine EP that manages to be comprehensive and varied within the confines of its three tracks... Its hard to find fault with this.

Creatures of the night behold Blindness for they are playing your tune. Hailing from the Big Smoke, theyve got that grindhouse electro pop feel that seems right at home after midnight. The title track of this EP - Confessions strafes you with ripped up riffs and droning loops that drill their way into your daylight starved brain. Crank the volume up a bit more and it all makes sense. Well sort of. Were talking a sort of madness here - the hormonal insanity of a broke down girl. Twisted and compelling and surely no stranger to the dangers of the dance floor, Beth Rettigs vocals exude the necessary torment. Broken goes all robotic but manages to sound vaguely mystical with the vocals drifting high above you over the kind of distorted psyched out guitar that makes you think of a half speed drug induced trance... One more for the soundtrack of your own personal urban wasteland

I love this Do you remember Curve? Well Blindness will certainly help you remember them and also have their own dark wave, brooding, ominous female vocal. Very urgent, very strong and powerful and its one of those ones that creeps up on you and pops a hood over your head and wrestles you to the ground and forces you to keep listening to it, which makes it sound like some sort of musical stalker... Another great track

Vibrant rich silky alternative darkwave pop with an electronic edge and a healthy touch of Curve/ Nine Inch Nails/Jesus & Mary Chain to gently propel it all along. Girl-voiced lushness, exquisite warmth, seductive dark wave electro pop and rising temperatures from the London based (four) piece. Beth Rettig on vocals, Debbie Smith (ex Curve/Echobelly) on guitar, Kendra Frost on bass.

A monster beat, layered squalls of guitar, and a vocal at once rueful and exultant - 'It was the best I could do in the state I was in,' sings Beth Rettig on 'Confessions', as the guitar ties itself in frayed knots and the bassline strides nonchalantly past in its big boots. Blindness match dirty technology with a big rock racket, and in 'Confessions' - a song about emerging bloodied but unbowed from some unspecified trauma - they've created an anthem that grabs both regret and triumph by the scruff of their necks and sets them marching... 'Broken' is all grinding bass and eruptions of volcanic guitar - that's Debbie Smith on guitar, ex-Curve, and her sheets of noise are instantly recognisable. 'No One Counts' is a bit of a ballad, but it's no shrinking violet. It's got a stuttering machine-beat, that untrammelled six-string overdrive, and plenty of the band's dirty cool. Dirt and coolness? Yes, that's the stuff we like.

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