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Archive for the ‘Blindness’ Category

Swansea boy with color blindness hoping for return of special glasses – Fall River Herald News

Saturday, March 4th, 2017

Deborah Allard Herald News Staff Reporter @debsallard

SWANSEA Kids lose their glasses. It happens.

But, when Connor Latessa lost his glasses a few weeks ago, the color went out of his life.

Connor, 13, is color blind. Most of what he sees appears in shades of brown.

But, Connors special glasses allowed him to see a full rainbow of colors until he lost those glasses at school or on the way home from school.

They made everything more colorful and vibrant, Connor said.

Rachel Latessa, Connors mom, said she surprised him with the $600 glasses hed been wanting for months. It was during a Christmas party with the family all there to see Connor try out his new glasses, while they held up colorful balloons.

Connor cried when he got his first look at all the reds and greens hed been missing, and especially when he saw the Christmas lights outside.

When I got them I was very emotional, Connor said. I really didnt know what I was seeing.

He said greens and browns are mixed up to him. And, he has a hard time distinguishing between blues and purples. Orange appears as green, and light blue as pink.

We found out when I was really little, Connor said.

Latessa said she noticed things she found odd when he was young, like calling his light blue blanket pink, and crying when he was given green lollipops, though they were really orange.

Different colors, he would call something else, and hes really smart, Latessa said.

When Connor was 5, she had him examined and found out for sure he was color blind. I wasnt surprised, Latessa said.

Its an affliction carried by the women in Latessas family and passed only to male children. Im a carrier, she said.

Her father saw only in black and white, and got in trouble when he was in school for coloring everything black the most vibrant color to him in the crayon box.

Connor understands everything about the condition, and even made it his science project at Joseph Case Junior High School, where he is a student.

Its because of the X and Y chromosome, Connor said, going on to explain the scientific intricacies. He said it affects one in 10 men and one in 200 women. Hes right, according to several websites.

Latessa said Connor being color blind is just something theyve learned to live with, though the glasses are a big help, especially outside where they work best.

It doesnt affect us too much, Latessa said. At times, Ill see something very colorful, and it makes me sad. I wish he could see it.

When a friend of the Latessa family learned that Connor had lost his beloved glasses, she started an online fundraising campaign and collected $500 in just a few hours.

Latessa said shes still hoping someone finds the glasses before buying a new pair.

The glasses look just like sunglasses and are EnChroma brand, which blends a marriage of color vision science and optical technology, according to its website.

If anyone locates the special glasses, contact Latessa at rmlatessa@aol.com or drop them at the office of Joseph Case Junior High School.

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Run color blindness tests on your websites – gHacks Tech News – Ghacks Technology News

Friday, March 3rd, 2017

Color blindness affects a large percentage of the population. Studies have shown that up to 8% of males and 0.5% of females of Northern European heritage are affected by red-green color blindness for instance. The ability to distinguish between colors gets worse with age as well.

As a webmaster, you may want to make sure that your site is accessible to visitors with color blindness, or difficulties distinguishing certain color patterns.

This gives those users a better experience on your site, and may prevent part of them from insta-closing the site when they run into accessibility issues.

Probably the best way of checking your websites quickly when it comes to accessibility for color blind visitors is to use a browser extension. Some sites and services may require more than that, but the extensions should be fine for the majority of webmasters out there.

RGBlind is a simple extension. It adds an icon to the main Firefox (or Chrome) toolbar on installation that you can click on to switch between two color blindness simulation modes.

You may switch to test Protanopia or Deuteranopia, and will notice that the color scheme of the site you are on changes immediately once you make a selection. The difference between the two forms is that in protanopia, the red retinal photoreceptors are missing, whereas in deuteranopia, it is the green photoreceptors that are missing.

Basically, what the test does is simulate color blindness, so that you can see how a color blind person would see the website.

Dalton for Chrome adds tests for eight different types of color blindness to the browser. Simple navigate to the website that you want to check for accesibility, click on the extension icon, and select one of the available types (Achromatomaly, Achromatopsia, Tritanomaly, Tritanopia, Deuteranomaly, Deuteranopia, Protanomaly, Protanopia)

The extension pains the colors of the site accordingly, so that you can verify what works, and what does not.

You need to click on each type separately to test them all. An option to rotate through all types automatically would be useful, but is not provided.

Another browser extension for Google Chrome that you may use to test a site#s accessibility for the color blind.

It works almost identical to Dalton above: click on the icon, select one of the available types, and watch as the site's color scheme gets modified accordingly by the extension. Supports the same eight types as Dalton.

Colorblind test extensions for Firefox and Chrome are helpful to webmasters and designers, as it allows them to test a site's or design's accessibility. The extensions are easy to use, and it should not take longer than a couple of minutes to run initial tests to find out how well, or not, the site displays for visitors affected by the various types of color blindness.

Now You: are you color blind? Are there many sites out there that don't show up correctly for you?

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Article Name

Run color blindness tests on your websites

Description

Find out how to run color blindness tests on your websites or designs, to make sure they are accessible by people affected by the various types of color blindness.

Author

Martin Brinkmann

Publisher

Ghacks Technology News

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Philanthropy vs. Blindness: What’s the Latest? Inside Philanthropy – Inside Philanthropy

Friday, March 3rd, 2017

If ever there were a problem that might seem tailor-made for philanthropy, it's fighting blindness. Losing sight is a horrifying fate for anyone to contemplate, and it's not surprising that blindness has motivated some deep-pocketed donors for at least a century. Over the past few decades, significant gains have been made in this area. In the United States, for example, the Foundation Fighting Blindnessco-founded by venture capitalist George Gund in 1971has raised over $600 million to fund research advances to prevent and cure retinal degenerative diseases that affect more than 10 million Americans. Worldwide, a range of efforts have sought to bring poor countries affordable cataract surgery. Cataracts are the main cause of blindness for half of the 40 million or so people who cannot see. Millions of people can see today because of these efforts.

This fight would seem eminently winnable, given that the World Health Organization estimates that 80 percent of blindness is avoidable, meaning it can be either prevented or reversed. Spurred on by that hopeful fact, the WHO galvanized a plan in 1999 called Vision 2020,a global initiative to prevent avoidable blindness, with a coalition that includes a number of foundations and top nonprofits.That milestone is now just three years away, and much work remains.

As usual, one key obstacle to faster progress has been funding. Never mind that the world's 2,500 billionaires now have assets of around $7.6 trillionthere's just never enough private or public money to fight blindness. Today's wealthy spend a fortune on luxuries even as millions of their fellow human beings cannot see. As a practical matter, reducing blindness has to compete with a bunch of other global health priorities, starting with diseases that actually kill people, like malaria and HIV/AIDS.

In addition, there aren't nearly as many major funders focused on preventing blindness as you might think. Very few of the largest U.S. foundations have made this a priority.

The Gates Foundation has patched in and out of this issue over the past 18 years, spending tens of millions fighting neglected tropical diseases that cause blindness, including large grants in the past to the Carter Center, the Task Force for Global Health, and Johns Hopkins University. But blindness hasn't been a big priority lately, at least compared to the foundation's investments in other areas.

Recently, the MacArthur Foundation announced that two of its eight semi-finalists for a special $100 million grant were organizations fighting blindness: Himalayan Cataract and the Carter Center. The fact these two made it into the top tier out of 2,000 proposals underscores the potential for big new money to make a huge impact (which is the goal of Mac's 100&Change competition).

While MacArthur's entry into the blindness space could be a game-changer, the Conrad N. Hilton Foundation stands out as one of the steadier big funders here. In particular, it's worked tirelessly to eliminate trachoma, a major cause of blindness. Trachoma is a result of repeated chlamydia trachomatis infections in the eyes. The infection, which typically starts in infancy or childhood, causes the eyelid to turn inward, resulting in corneal scarring caused by the eyelashes rubbing on the eyeball. Trachoma is incredibly painful, and if left untreated, leads to irreversible blindness. The debilitating disease is endemic in some of the poorest countries in the world.

Hilton uses the World Health Organizations (WHO) SAFE strategy (surgery, antibiotics, facial cleanliness, and environmental improvement) approach to eliminating blinding trachoma in Mali, Niger, and Tanzania. The foundation has played a crucial role in eliminating the disease in Ghana, which achieved its elimination targets in 2014. While this is a major success, Hilton isnt celebrating just yet. The foundation still has blinding trachoma in its sights and just awarded millions in grants to eliminate the disease.

Related: Researching Blindness Treatments? Conrad N. Hilton Foundation is on Your Side

Hilton made a total of $11.725 million in grants to three organizations that know more than a little bit about trachoma and avoidable blindness.

At just under $6 million, Helen Keller International received the largest award in this round. Established over 100 years ago, Helen Keller International has been on the front lines of the global trachoma battle since the 1950s, and has over 120 programs across Africa and Asia. Using the WHO's SAFE strategy as well, Helen Keller administered more than 80.5 million integrated neglected tropical disease (NTD) treatments in six African countries in 2016.

Coming in a close second behind Helen Keller International, the Carter Center received a $5.1 million grant from Hilton. The Carter Center has been a leader for over 30 years in the war against NTDs such as guinea worm, river blindness and trachoma. Since 1999, Carter has implemented the SAFE strategy in Mali and Niger. The Carter Center has facilitated thousands of surgeries and administered more than 500 million doses of antibiotics through its mass drug administration programs. Carter has also backed the construction of nearly 220,000 latrines in Mali and Niger. Better water, sanitation, and hygiene plays a critical role in preventing the spread of trachoma.

The final grant in this round was awarded to Sightsavers, which received $650,000. Sightsavers is a U.K.-based organization that has been working to eliminate avoidable blindness for six decades in over 30 countries around the world. Over the years, the group has supported more than 575 million treatments for blinding and potentially blinding conditions, and backed over 8 million surgeries to restore sight. Caroline Harper, CEO of Sightsavers, called Hiltons donation vital to meeting the WHO target for eliminating blinding trachoma by 2020.

Helen Keller International and the Carter Center are using the Hilton grants for trachoma prevention and elimination programs in Mali and Niger. Sightsavers is using its donation from Hilton to back its work in Mali. Both countries are within reach of their trachoma elimination targets.

Related: Where Have Hiltons Global Grants Been Going Lately?

The Hilton Foundations $11.725 million in grants certainly provides a nice boost toward eliminating trachoma in Mali and Niger, and the leveraging power of those funds could help both countries reach the elimination finish line. Hiltons latest trachoma grants require a dollar-for-dollar match by 2020 from each organization. Meaning, the foundation is effectively mounting a three-year, $23.45 million trachoma eradication campaign.

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Association’s Name Change Focuses on Sight, Not Blindness – Associations Now

Friday, March 3rd, 2017

The New Hampshire Association for the Blind doesnt want to limit its mission because of its name.

As a result, this week the 105-year-old organization announced that it is changing its name to Future in Sight, which the group says better reflects its goal and overall duties within the state.

In an interview with New Hampshire Public Radio, Future in Sight President and CEO David Morgan noted that 93 percent of the people the organization serves have some form of sight loss but arent blind.

From the interview:

Up until recently, we never served babies. We served seniors, but not outside their home. And more and more, were discovering there are some 30,000 New Hampshire residents with profound sight loss, and we only served about 1,100 last year. So theres certainly a compelling need out there thats left unfulfilled. And frankly, the word blind in our name inhibited a lot of conversations, particularly in doctors offices and between doctors and their patients.

The latter situation proved a significant problem for the organization, according to Morgan, who told the Concord Monitor that the group had expanded its mission in recent years, partly because of changes with the states offerings. As a result, the association has received more referrals from doctors.

But these referrals created problems because members of the public were thrown off by the name.

The new name already has had an important impact on these conversations, Morgan stated.

As we stopped using the word blind, what we did was create new conversation around the word sight and the use of whats left for residual sight for both school-age kids and adults, he explained in his New Hampshire Public Radio interview.

In a blog post, Morgan added that the group is also expanding its mission to bordering states around New Hampshire.

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New Retinal Device May Give Hope To The Blind – CBS Chicago

Thursday, March 2nd, 2017

March 1, 2017 10:08 PM By Marissa Bailey

(CBS) A blind man can see light for the first time in 20 years, all thanks to a revolutionary device being researched right here at the University of Illinois-Chicago.

CBS 2s Marissa Bailey explains how it could change the lives of the blind.

This is no regular eye doctors appointment.

This is Bob Selbys first check-up since Dr. Jennifer Lim at UIC implanted the groundbreaking retinal device called the Argus II.

Ive been legally blind my whole life, really, Selby says.

The 55-year-old was born with Retinitis Pigmentosa. He was diagnosed in his 20s and completely blind by 35.

The part of the retina that doesnt work is the part of the retina that gathers the light. The photoreceptors are dead but the inner retina works, Dr. Lim explains.

Selbys device was implanted in October and thenturned on in November. Thats when he saw light flashes for the first time in more than 20 years.

Now he can see edge and contrast effects and can pick people out, but before he didnt know where they were unless they would say something, Lim says.

Heres how the device works: The lens on Selbys glasses transmits an image through a video processor box. It wirelessly sends instructions to the implant on Selbys eye. Those messages stimulate Selbys retina to send signals along the optic nerve to his brain, which allows him to see.

Within minutes of turning on the device, Selby was navigating unfamiliar hallways by himself.

Wow! Ive never been so happy to see a wall before, he said that day.

Selby calls the technology a game-changer.

For patients, its huge.To be able to see light and then not only to see the light but to have the light mean something, Lim adds.

Selby practices with his new found sight a couple of hours a day.

He says if he can see light flashes now, this may be the beginning of the end for blindness.

Imagine what they could do in five to 10 years, he says.

Selby is one of only 60 people in the world with this FDA-approved retinal implant. UIC is one of 13 sites in the U.S. where its being used.

The Argus II is now being studied in Europe for people with macular degeneration.

Marissa Bailey is the weekend anchor of the CBS 2 Chicago morning newscasts and a general assignment reporter for the station. Marissa joined the station in March 2012 as a reporter and was promoted to anchor the stations Saturday and Sunday...

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Beware Of This ‘Thief Of Sight’ That Can Gradually Cause Blindness – malaysiandigest.com

Thursday, March 2nd, 2017

Details Published on Thursday, 02 March 2017 08:32 Written by Thorsten Marquardt

Glaucoma, the silent thief of sight, is a group of diseases caused by damage to the optic nerve in the eye.

Without any warning signs or symptoms it will slowly take away the affected persons eye sight and can even cause blindness if not treated appropriately.

Tanaletchimy Rajaratnam, 63, felt completely healthy and had no symptoms at the time she was diagnosed with high eye pressure during a routine eye screening in the UK.

With high eye pressure being the number one cause for glaucoma, she decided to start the treatment right away.

Taking the risk seriously, going for regular checkups and starting with the treatment early enough helped keeping the diseases progress at bay.

This is the reason why today, 10 years after she was diagnosed with glaucoma, her eye sight has not been significantly affected.

Without early detection and swift action, this could have played out very differently.

Another patients son, Mr Wong, told MalaysianDigest, at the Tun Hussein Onn National Eye Hospital that his 75 year old father had been affected by glaucoma for a long time without even noticing it.

Only after the disease had already severely damaged his eyes and even started to cause pain, he finally consulted a doctor.

Without appropriate treatment, he is now at risk of going blind.

Before being diagnosed with the disease, like most people, both patients werent even aware of its existence. Like many other glaucoma patients in Malaysia, Wong andTanaletchimy accounts of the onset of the disease highlights the invisible nature of this condition until it is too late.

The Malaysia Glaucoma Society had produced the following public announcement about this disease a few years back to create awareness of this 'silent thief of sight'.

The World Glaucoma Week held in March each year takes place on 12 to 18 March 2017 and to help raise awareness, we have decided to highlight this often 'invisible' illness and look at a local eye hospital's role in helping glaucoma patients.

The Silent Thief Of Sight

If the optic nerve that connects the eye to the brain is too damaged, it will not be able to send an accurate and complete picture to the brain causing reduced eye sight.

This results in people having blurry vision and a restricted field of view or missing objects in their view.

Glaucoma usually comes without any symptoms and often stays undetected for a long time.

Not always, but very often, glaucoma is caused by high eye pressure damaging the optic nerves.

To be more specific, glaucoma usually develops when the production of an eye fluid called aqueous humour either increases or fails to drain properly.

This causes the pressure in the eye to rise which can damage the fibres in the optic nerve resulting in interruptions to the transmission of visual messages to the brain.

Eye drops are used to reduce the eye pressure and keep it stable to prevent further damage to the nerves.

Eye pressure is the main cause for glaucoma, but not required for its development.

People with normal eye pressure can still be affected, while people with high eye pressure are more likely to be at risk but dont necessarily develop the disease.

It is estimated that half of the people affected by glaucoma do not know that they have it, which is a serious problem because if left undetected and untreated it can lead to blindness.

According to the World Health Organization, Glaucoma is the second most common cause of blindness worldwide and it is estimated that 4.5 million persons globally are blind due to glaucoma.

If left untreated, most types of glaucoma progress (without warning nor obvious symptoms to the patient) towards gradually worsening visual damage and may lead to blindness, states the World Glaucoma Association.

Since there is no cure, the damage caused to the optic nerves and the reduced eye sight are irreversible, therefore it is important to detect it early.

There is no cure for glaucoma as yet, and vision loss is irreversible. However medication or surgery (conventional or laser) can halt or slow-down any further vision loss. Therefore, early detection is essential to limiting visual impairment and preventing the progression towards severe visual handicap or blindness, states the World Glaucoma Association.

Everybody Is At Risk Of Glaucoma

Datuk Dr. Linda Teoh, a full time consultant ophthalmologist and glaucoma specialist at the Tun Hussein Onn National Eye Hospital (THONEH), told MalaysianDigest that everybody can be affected by glaucoma.

There are certain risk factors, like for example high eye pressure and a family history, but the disease can affect anyone.

It is not just about the eye pressure. The eye pressure might be normal but the person can still develop glaucoma. There can also be people with high eye pressure but no glaucoma. Too many people look only at the eye pressure, she said.

People with high eye pressure are at a much higher risk of getting glaucoma and it is generally assumed that people with a family history of glaucoma already have a 1 in 4 chance of developing the disease.

There are, however, many other factors that come into play.

Everybody is potentially at risk of developing glaucoma, but there are certain risk factors that increase the likelihood.

People above the age of 60, people with diabetes, people who have used steroids for a long period of time and people with physical eye injuries are also at a higher risk.

Some ethnicities are more prone to the disease than others.

The Glaucoma Research Foundation found that African Americans are more likely to be affected by glaucoma than Caucasians.

The ingredients of certain weight loss appetite suppressant pills are also linked to an increased risk.

In Malaysia around 1.8 percent of the population is affected by glaucoma and, according to surveys, only 21 percent of the population are even aware of the disease.

Since glaucoma is very unpredictable, can affect anyone and comes without warning, routine eye checkups, measuring eye pressure and conducting visual field tests are crucial in detecting and treating the disease early enough to avoid major irreversible damage to the eye sight.

Education And Cooperation Between Doctor And Patient Are The Key To A Successful Treatment

When it comes to treating glaucoma, it is very important that the patient and the doctor are on the same page.

Since glaucoma is a disease that continuously gets worse while causing irreversible damage, regular checkups and adjustments to the treatment are very important.

In order to keep the disease from progressing, it is required to keep the eye pressure low and stable.

Datuk Dr. Linda Teoh, a full time consultant ophthalmologist and glaucoma specialist at the Tun Hussein Onn National Eye Hospital (THONEH)Glaucoma is actually a group of diseases causing damage to the optic nerve of the eye. By controlling the eye pressure, the drops can slow down the progress of glaucoma, Dr. Linda explained.

I think what is important is education. Patients should know the nature of the disease and understand how it progresses.

Despite the aggressive nature of the disease and lack of cure, it is possible to prevent the loss of eye sight through appropriate treatment.

This, however, can be costly, time consuming and requires the patients to actively take an interest in informing themselves about the disease and be compliant with their medication.

Dr. Linda thinks that a lack of education and knowledge about the disease leads many patients to be neglectful and hamper the effectiveness of the treatment.

They feel there is no improvement in spike of treatment. They fail to understand the nature of the disease. Then they blame the doctor if they dont get better. They always want to improve, but what they dont understand is that Glaucoma cannot be improved; its progress can only be slowed down. What they need is education, she said.

In order to successfully treat the disease and prevent it from progressing, patients have to go for regular checkups, use the prescribed medicine correctly, meet doctors regularly to adjust the treatment based on changing conditions and undergo surgery (to control the eye pressure) if the necessity arises.

The drops used to reduce the eye pressure, for example, have to be adjusted regularly depending on whether the eye pressure are effectively controlled in order to avoid fluctuations that damage the optic nerve further.

Dr. Linda opined that patients who are either too uninformed and ignorant about the disease or dont trust the doctors are more likely to fail at properly treating the disease.

Tanaletchimy, who managed to slow down the progress of the disease by being very proactive and engaged with her doctors also sees cooperation between doctors and patients as the most important factor.

Just listen to what the specialists have to say. They are the experts. You must have confidence in the doctor and just follow what the doctor suggests, she said.

According to Dr. Linda, education, cooperation with the doctor, early detection and early treatment are the most important factors in successfully treating glaucoma.

In conjunction with the World Glaucoma Week 2017 starting from March 12, the Tun Hussein Onn National Eye Hospital (THONEH) will be hosting an open day on 22 March 2017 (Wednesday).

There will also be a presentation ceremony and a series of programmes including an eye health talk open to the public. For further information, contact THONEH at 603-7718 1588 or email This email address is being protected from spambots. You need JavaScript enabled to view it..

-mD

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‘Treasure map’ identifies first genetic clues to form of blindness – Blue Mountains Gazette

Thursday, March 2nd, 2017

27 Feb 2017, 6:11 p.m.

Researchers have identified genetic clues which could reveal a person's risk of going blind.

Tom Doumani thought something was up when he started having trouble reading street signs while driving. Letters seemed to be missing and, if the street name was an unfamiliar one, he had no way of guessing what it might be.

It was enough to prompt him to go and get his eyes tested. However the results showed his long distance vision was fine.

Unconvinced all was as it should be, he mentioned it to his GP who referred him to an eye specialist. This time the tests picked it up. Dr Doumani had the rare and rather awkwardly named Macular Telangiectasia type 2.

Like many rare conditions, little is known about what causes "MacTel 2", which in scientific circles is known as idiopathic juxtafoveal telangiectasia. Idiopathic meaning "of unknown cause".

However that may have changed, thanks to research led by Melbourne scientists which has found "a treasure map" revealing the location of the genetic triggers behind this little-understood form of blindness.

Outlined in the journal Nature Genetics, it is the first clue as to what causes MacTel 2, an incurable and untreatable degenerative disease which affects people from age 40 upwards.

The condition is characterised by an abnormal growth of blood vessels in the macula. Patients lose their central vision and tasks such as driving and reading can become impossible.

The international study was led by Walter and Eliza Hall Institute of Medical Research scientists Melanie Bahlo and Thomas Scerri.

The research team, including scientists in New York and London, analysed more than 6 million genetic markers in the genome of patients with the condition and compared them to those without.

Among the 476 people diagnosed with MacTel 2, genetic similarities were found in five key regions of the genome.

Curiously four of the five regions are associated with a person's metabolism. Those with MacTel 2 recorded lower levels of the basic amino acids glycine and serine.

"That was a bit of a surprise to say the least," Professor Bahlo said.

The fifth region identified, in what Professor Bahlo has described as "our treasure map", is tied to the size of retinal blood vessels.

"This is the first time we have been able to say with certainty that this is a genetic condition," she said. "And the map tells us where to 'keep digging' in order to discover the specific genes implicated in MacTel 2."

Identifying the specific genes would lead to improved diagnostic testing for the disease which is notoriously difficult to identify and also developing ways to prevent or stop its progression.

Diagnosed in 2012 at the age of 61, retired corporate banker Tom Doumaniwas among theMelbourne participants, sourced through Centre for Eye Research Australia. Heknows that while he may not benefit directly from participating in the study, he is contributing to the global search for a cause or cure.

"To help advance the knowledge, that's what appealed to me in taking part," he said. "I had no hesitation in participating."

The story 'Treasure map' identifies first genetic clues to form of blindness first appeared on The Sydney Morning Herald.

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World-first genetic clues point to risk of blindness — ScienceDaily – Science Daily

Wednesday, March 1st, 2017
World-first genetic clues point to risk of blindness -- ScienceDaily
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Scientists have discovered the first evidence of genes that cause Macular Telangiectasia type 2 (MacTel), a degenerative eye disease which leads to blindness ...

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Wayne State University scientists discover the Zika virus can … – Fox17 – Fox17

Wednesday, March 1st, 2017

DETROIT Scientists with Wayne State University say they are the first to publish research to show the Zika virus can damage retina cells in the eyes, and in some cases cause blindness.

The key message of the study is that indeed the Zika virus can cause damage, said Dr. Ashok Kumar, microbiologist and assistant ophthalmology professor with Wayne State University School of Medicine at the Kresge Eye Institute.

Dr. Kumar led a team which launched research in July to publish their study in JCI Insight, the Journal of Clinical Investigation Feb. 23.

Using mice Dr. Kumar says the Zika virus can infect and cause lesions in retina cells, causing damage and in some cases cause blindness. Their research showed the Zika virus mostly killed cells specifically lining the blood-retinal barrier, the retinal endothelium, and retinal pigment epithelium.

Zika virus can actually infect those cells, and we did studies and we found it can replicate in those cell types and ultimately it kills those cells, said Dr. Kumar.

Their study builds on existing research published May 2016 in the Journal of the American Medical Association Ophthalmology that linked the Zika virus to eye problems. Researchers showed that some infants born with congenital Zika infection and microcephaly-or significantly smaller head and underdeveloped brain-in the northeast state of Brazil, Bahia, they also had problems in their retinas, other organs, and some hearing loss.

Pretty much the whole eye can be infected with the Zika virus, said Dr. Gary Abrams, ophthalmology professor with Wayne State University School of Medicine at the Kresge Eye Institute, who assisted Dr. Kumar with the clinical aspect of this study.

Dr. Abrams says about one third of infants born with Zika will develop eye issues they have discovered, whereas 15 percent of adults with Zika will have some sort of ocular impact, but most do not get a retinal infection.

This is a virus thats fairly pervasive: once the infection occurs it can be pretty much all over the body, including in the eyes, in the tears, and elsewhere, said Dr. Abrams.

Currently, Dr. Kumar says they are continuing research in hopes of developing methods to track and treat Zika infections. According to the Centers for Disease Control and Prevention, there is no known treatment at this time.

There are so many questions we dont know, said Dr. Kumar. First thing is: how does the virus replicate? How long is it going to replicate? And what will be the visual outcome.

The big question really is that Zika virus was discovered in 1947, so its about 70 years, and why suddenly is it becoming so prevalent?

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Did you know diabetes can cause blindness? – Londoner

Wednesday, March 1st, 2017

Diabetics who may be experiencing vision loss without realizing it are the target of a new awareness campaign St. Josephs Health Care London hopes will lead to more screening.

Vision loss can be sneaky, said London-based optometrist, Harry Van Ymeren, in a news release. In my practice, I have seen it many times. People think they are fine and we discover a problem. The point of screening is to catch it before it becomes too late.

Diabetes is a chronic disease that prevents the body form making or using insulin, in turn increasing sugar levels in the blood stream. The development of early-onset cataracts and glaucoma is more likely for people who have diabetes, but Tom Sheidow, an ophthalmologist at the Ivey Eye Institute, said the main threat is the effect of diabetes on the retina, the part of the eye that allows you to see.

This is why screening early and often is so important for those with diabetes, he said. Diabetes can affect all blood vessels in your body, including those inside your eye. Diabetic eye damage, also called diabetic retinopathy, occurs when there is a weakening of the blood vessels in the retina that can result in swelling, the abnormal growth of blood vessels, and potentially severe bleeding. If diabetic retinopathy is left untreated, blindness can result.

According to St. Joes, estimates put the number of people in Canada with some form of diabetic retinopathy at around two million. It is the most common cause of blindness in people under age 65 and the most common cause of new blindness in North America.

Sarah MacArthur was diagnosed with type 1 diabetes at the age of three and has been cautious with her care because she understands the importance of screening. MacArthur said she has discovered symptoms of diabetic retinopathy in the past four years because of screenings with Van Ymeren.

I had no signs at all, she said. There was nothing that prompted me or made me think something was wrong with my vision. We are keeping a close eye on any changes so we know immediately if there is a concern.

A routine eye examination is all it takes to diagnose potentially threatening changes that can cause blindness. But once damage has occurred, the effects can be permanent.

People who feel completely healthy are the focus of this diabetes vision screening awareness campaign, said Sheidow. Anyone with diabetes (both type 1 and type 2) should have their vision checked.

Referrals to an optometrist from a family doctor are not required and in Ontario, the cost of an eye exam for people living with diabetes is covered through OHIP. Resources to locate an optometrist are available at opto.ca. For communities without an optometrist, an ophthalmologist is an option, said Van Ymeren.

It doesnt matter if you see an ophthalmologist or an optometrist, as long as you get your eyes checked. Yearly screening is free for people with diabetes.

For more information, visit diabetesvisionscreening.ca

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Genetic clue to form of blindness could lead to early diagnosis – ABC Online

Tuesday, February 28th, 2017

Posted February 28, 2017 17:44:11

The first genetic indicator of an eye disease which results in blindness has been discovered by an international team of researchers.

The degenerative eye disease Macular Telangiectasia type 2, or MacTel, is incurable and usually strikes people who are over the age of 40.

Up until now identifying a possible cause for the disease has been difficult.

Scientists are unsure as to how many Australians have MacTel, but they estimate somewhere between 500 and 1,200.

The disease affects the macular the centre of the eye said Professor Melanie Bahlo, from the Walter and Eliza Hall Institute in Melbourne.

"What happens is blood vessels dissolve and start growing into the centre of the eye, and that leads to blindness," she said.

"And there's also the crystalline deposits that form."

This leads to a gradual loss of central vision over a period of 10 to 20 years, impacting people's use of their sharp vision for tasks like driving and reading.

There were also signs that there could be genetic predispositions for MacTel in certain people.

"You can get several family members [with the disease], in the worst case scenario," Professor Bahlo said.

"That usually means that there's a genetic basis to the disease."

To find out more, researchers collaborated with teams in London and New York to analyse the genetic data of nearly 500 MacTel patients, and 1,700 people without the disease.

Professor Bahlo said they carried out statistical analysis of DNA data from about 6 million markers in the genome of patients with the condition and then compared them to those without.

They found genetic similarities in five key regions of the genome.

Professor Bahlo said four of the five genome regions identified were connected with two crucial amino acids and the fifth region was connected with the size of blood vessels in the retina.

She likened the discovery of the five genetic risk locations to a "treasure map" and said scientists would now keep digging to find out more about the genes associated with MacTel.

Professor Bahlo said they hoped the discovery would eventually help identify people at risk of developing the eye disease.

"For the first time we know a pathway to investigate the future by medical research with future studies in the lab," she said.

"We'll try and validate those findings further. But we've also got some potential biomarkers which will help us diagnose the disease, which is difficult to diagnose, and just pinpoint people who may have faster or slower progression."

The study will be published in the journal Nature Genetics.

Topics: dna, science-and-technology, genetics, cloning-and-dna, eyes, diseases-and-disorders, health, medical-research, research, melbourne-3000, australia, vic

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Genetic clue to form of blindness could lead to early diagnosis - ABC Online

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Americans Are Terrified of Going Blind – Esquire.com

Tuesday, February 28th, 2017

Americans are a fearful lot. In 2016, one survey found 60 percent of Americans feared corrupt government officials, 41 percent feared a terrorist attack, and 35.5 percent were afraid of Obamacareall fears they channeled into an election. In a separate survey conducted at Johns Hopkins, a majority of Americans (47.4 percent) said loss of sight was the "worst possible" health problem someone could go through. Now, ironically, 56 percent of Americans are afraid they'll lose their health insurance. Blindness, for those keeping track, is often preventable with regular healthcare.

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In a study of 2,044 adults, blindness was ranked as more dreaded than loss of hearing, memory, speech, a limb, or contracting HIV/AIDS, according to The New York Times, because it would have the worst perceived effect on quality of life and a person's independence. Adult blindness is usually caused by four diseasescataracts, glaucoma, diabetes, and age-related macular degenerationthe signs of which can be detected pretty early on by an eye doctor.

With access to an ophthalmologist and a desire for preventative healthcare, that's one major American fear taken care offor now. Shall we tackle government corruption next?

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Americans Are Terrified of Going Blind - Esquire.com

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Aids for Vision Loss, From Those Who’ve Been There – New York Times

Monday, February 27th, 2017

New York Times
Aids for Vision Loss, From Those Who've Been There
New York Times
But he insisted, Blindness does not cut me off from the world. He cited skillful use of a cane, travel devices that tell him where he is and what is around him and periodicals available in real time by telephone among myriad other gadgets that see ...

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Retinopathy of Prematurity and Childhood Blindness: Why is it Still Happening – The Ring of Fire Network

Monday, February 27th, 2017

Several years ago, an article published in the Ophthalmic Mutual Insurance Company Digest reported that the size and amounts of malpractice judgments were discouraging ophthalmologists from doing screenings for retinopathy of prematurity (ROP).

The issue was addressed over twenty years ago in a letter from an ophthalmologist to the administration of the hospital where he was employed as well as the state medical board. The letter outlined the reasons for his decision to no longer perform ROP screenings:

Guidelines from the Cryotherapy of Prematurity Study must be followed exactly. The timing of the evaluation and follow-up visits are critical. This is often not under the physicians control (i.e., patients family compliance to follow-up visit requests is at times marginal). The risk of liability in these cases is high. The emotional trauma of dealing with any kind of litigation is great.

A few years later, a study published in Transactions of the American Ophthalmological Society indicated that doctor errors in ROP examinations are fairly common. One of the problems addressed in that piece is inconsistency.

While the standard of care for specialists is national, it does not necessarily apply to general practitioners. When it comes to primary care physicians or pediatricians, the standard of care is determined on a local or regional basis, and can differ from one jurisdiction to the next.

It also comes down to the question of who bears the most responsibility when it comes to diagnosing and treating ROP. Obviously, the pediatricians or neonatologist is part of the equation. However, because this is an eye and vision issue, input from an experienced ophthalmologist is also necessary. This is especially important because this professional is held to a higher standard of care and has dedicated his/her career to the study of vision issues.

This said, the majority of ROP cases that generate lawsuits found the failure occurred when it came to transferring care of the patient after being discharged from the hospital. In a study of 13 legal actions involving ROP, three were found to be due to delayed follow-up examinations. In another case, there was failure on the part of the screening facility to refer the outpatient case to the ophthalmologist, while one case centered around an unsupervised resident physician who was charged with care of the patient. In the remaining eight cases, the hospital did not transfer the case at all once the patient had been discharged.

The main point is that most cases of ROP are treatable and even preventable. However, this requires communication and coordination between the pediatrician, the neonatologist, the ophthalmologist and the family affected. All involved parties should also have access to knowledge of the latest guidelines for screening and treatment. In an age of cost-cutting and belt-tightening, however, this does not always occur; and unfortunately its the family and child who end up suffering an immeasurable loss.

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Retinopathy of Prematurity and Childhood Blindness: Why is it Still Happening - The Ring of Fire Network

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‘Treasure map’ identifies first genetic clues to form of blindness – The Sydney Morning Herald

Monday, February 27th, 2017

Tom Doumani thought something was up when he started having trouble reading street signs while driving. Letters seemed to be missing and, if the street name was an unfamiliar one, he had no way of guessing what it might be.

It was enough to prompt him to go and get his eyes tested. However the results showed his long distance vision was fine.

Unconvinced all was as it should be, he mentioned it to his GP who referred him to an eye specialist. This time the tests picked it up. Dr Doumani had the rare and rather awkwardly named Macular Telangiectasia type 2.

Like many rare conditions, little is known about what causes "MacTel 2", which in scientific circles is known as idiopathic juxtafoveal telangiectasia. Idiopathic meaning "of unknown cause".

However that may have changed, thanks to research led by Melbourne scientists which has found "a treasure map" revealing the location of the genetic triggers behind this little-understood form of blindness.

Outlined in the journal Nature Genetics, it is the first clue as to what causes MacTel 2, an incurable and untreatable degenerative disease which affects people from age 40 upwards.

The condition is characterised by an abnormal growth of blood vessels in the macula. Patients lose their central vision and tasks such as driving and reading can become impossible.

The international study was led by Walter and Eliza Hall Institute of Medical Research scientists Melanie Bahlo and Thomas Scerri.

The research team, including scientists in New York and London, analysed more than 6 million genetic markers in the genome of patients with the condition and compared them to those without.

Among the 476 people diagnosed with MacTel 2, genetic similarities were found in five key regions of the genome.

Curiously four of the five regions are associated with a person's metabolism. Those with MacTel 2 recorded lower levels of the basic amino acids glycine and serine.

"That was a bit of a surprise to say the least," Professor Bahlo said.

The fifth region identified, in what Professor Bahlo has described as "our treasure map", is tied to the size of retinal blood vessels.

"This is the first time we have been able to say with certainty that this is a genetic condition," she said. "And the map tells us where to 'keep digging' in order to discover the specific genes implicated in MacTel 2."

Identifying the specific genes would lead to improved diagnostic testing for the disease which is notoriously difficult to identify and also developing ways to prevent or stop its progression.

Diagnosed in 2012 at the age of 61, retired corporate banker Tom Doumaniwas among theMelbourne participants, sourced through Centre for Eye Research Australia. Heknows that while he may not benefit directly from participating in the study, he is contributing to the global search for a cause or cure.

"To help advance the knowledge, that's what appealed to me in taking part," he said. "I had no hesitation in participating."

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'Treasure map' identifies first genetic clues to form of blindness - The Sydney Morning Herald

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The sorghum plant that could tackle blindness – Devex

Monday, February 27th, 2017

Sorghum farmer Dorothy Warubua in Kiatine Village, Kenya. Photo by: CropLife

Up to half a million children around the world are going blind every year due to a lack of Vitamin A in their diets. According to the World Health Organization,Vitamin A deficiency, which afflicts 250 million children worldwide is the leading cause of preventable blindness in children and increases the risk of disease and death from severe infections. It is a public health problem in more than half the worlds nations, especially in Africa and Southeast Asia, affecting young children and pregnant women in low-income countries the hardest.

In Kenya, scientists are tackling this problem by developing biofortified sorghum, a staple crop that has been genetically modified to contain higher levels of Vitamin A. More than 300 million sub-Saharan Africans depend on sorghum as their primary calorie source. Its drought- and heat-tolerant properties mean it is a vital crop in drought-prone countries, where irrigation is not always accessible or affordable. Improving the nutritional level of staple crops can provide both food and nutritional security.

TheAfrica Biofortified Sorghum, or ABS, project is a public-private partnership established to tackle chronic Vitamin A deficiency in children, as well as improve levels of zinc and iron. If it gets commercial approval, it will be the first-ever biotech sorghum on the market. LikeGolden Rice, biofortified sorghum is a cutting-edge approach to food security and quality.

In terms of tonnage, sorghum is Africas second most important cereal and because it originated in east Africa, Africans know how to plant, cook and eat it. Dr. Titus Magomere, a lecturer in biotechnology at Kenyatta University,is one of 70 scientists involved in the ABS project. He says it is the obvious crop to focus on.

With the work that I am doing with biofortified sorghum, we are not trying to change the way people live, we are just improving the available nutrients in what they already have, he said.

Dr. Magomere and his team have already increased the Vitamin A available in sorghum test plants.

This is the first step, he explained. The second step has been to increase availability of iron and zinc and this has been done by reducing the levels of a protein that binds iron and zinc in the plants. We hope once the product is ready, a meal of sorghum, which will be available to the local farmers, will reduce nutritional deficiencies significantly.

Farmers like Dorothy Warubua from Kenya are hoping to take these scientific advancements from the lab to the fields.

With the work that I am doing with biofortified sorghum, we are not trying to change the way people live, we are just improving the available nutrients in what they already have.

When I was young, many people grew sorghum, but then people were encouraged to grow other crops, and started looking down on sorghum, she said.

Farmers were encouraged to grow maize in particular, but after a number of poor harvests, the Kenyan Ministry of Agriculturesupported the reintroduction of sorghum.

Sorghum needs very little rain. If you plant sorghum and maize at the same time, the sorghum will succeed but the maize often will not so that's why we prefer sorghum, says Warubua.

A reliable harvest also means a more secure source of nutrition and income for farmers and their families.

You have to have a farmer who is going to harvest so that the people will eat, emphasizes Warubua.

WithFood Heroeslike Warubua growing food for her community, and Magomere enhancing micronutrients in staple crops, the chronic nutritional deficiencies that haunt millions of African children can start to be addressed.

Were looking for more farmers and scientists to tell their story. Help us uncover the men and women who are securing food supplies for future generations so we can share their story. Submit your Food Heroes stories or your own story here.

Join the Devex communityand access more in-depth analysis, breaking news and business advice and a host of other services on international development, humanitarian aid and global health.

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Empathize with deaf-blindness in world’s 1st interactive space … – Times of India

Sunday, February 26th, 2017

Ahmedabad: Picture this: You walk into a room and after two steps inside, you are past a curtain and you can't see anything-there isn't a single ray of light. There is 'white noise' in the background that is suppressing all other sounds around. Your only guide is the walls and things you can touch and the smells you can identify. The thought may either be intimidating, disturbing or even adventurous and beautiful. Such is the space designed by city-based space designer duoFreyaan Anklesaria and Mirant Tiwarito let people experience the life of a deaf-blind person for a few minutes. In fact, it is the world's first interactive space to emulate deaf-blindness. Known as 'SenseX', indicating Sensory Experience, the interactive space is created with a view to making people empathize with deaf-blindness, a disability even though long-prevailing in India, that was recognized as a disability in the last winter session of the Parliament with the new disabilities bill. At present, the installation of the experiential space is kept at the campus of Blind People's Association. "Deaf-blind people lose 95% of their input information as their receptive sensory organs are impaired. Our idea is not to let people get disturbed but rather let them experience the life of a deaf-blind person and see beauty through their eyes," explained Freyaan, who is a city-based interior designer. "The space is still being improvised with minor changes to make the experience more wholesome," she added. The entire project is funded by Sense International India, an NGO which is working to address multi-sensory impairment, mainly deaf-blindness. Sharing more details about the project, Mirant, who is the co-founder of Hats & Beards, a design agency, said, "Initially during the research phase, we looked for existing spaces that were designed to simulate deaf-blindness so that we get an idea to implement them better. While we came across experiential spaces for deafness and blindness separately, we did not come across a single one that lets one experience both."

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Wayne State study finds Zika virus may cause blindness – Crain’s Detroit Business

Friday, February 24th, 2017

Crain's Detroit Business
Wayne State study finds Zika virus may cause blindness
Crain's Detroit Business
A study released Friday by a team of Wayne State University researchers in Detroit shows that Zika virus may cause blindness. The report, led by microbiologist Ashok Kumar, found that the virus can spread and damage tissue in the eye's retinal cells ...
Wayne State Vision Researchers Show Zika Virus Can Damage Retina and Cause BlindnessInfection Control Today

all 2 news articles »

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Blindness charity returns as partner for Recency Run – Leamington Observer

Thursday, February 23rd, 2017

BRITISH Blind Sport is returning as a charity partner for the Wright Hassall Regency Run.

Organised by the Leamington and District Round Table the 10k run takes place on Sunday April 2.

The Leamington-based charity which helps blind and partially sighted people to get active and play sport are hoping to encourage more people of all running abilities to become guide runners.

Following the success of the Rio Paralympics the profile of disabled sport is higher than ever and the charity wants runners of any ability to run the 10k and raise funds for them to support their Find a Guide service which pairs visually impaired runners and guide runners.

Fundraising manager for British Blind Sport, Ian Carr, said: The Regency Run is a fantastic event and were really grateful to the Round Table for once again supporting us this way.

The event has really helped us to raise the profile of British Blind Sport in Warwickshire and funds raised will support our guide running programme so we can continue our work in providing sporting opportunities for visually impaired people.

And Mark Chambers from the Round Table added: This is our 13th year hosting the Regency Run, and we hope to see more entries than ever before.

There is always such a good atmosphere and a great sense of community so it should be a fantastic day.

The run has helped to raise thousands of pounds for British Blind Sport over the last few years and were looking forward to supporting the work of the charity again.

Visit http://www.regency10k.co.uk to enter and http://www.britishblindsport.org.uk for further details.

* A WARWICK community centre can continue delivering youth sport activities thanks to cash raised by the Regency Run.

The Gap Community Centre has received 2,000 and will receive 4,000 more over the next two years from the Leamington Round Table as a result of funds raised by the Regency Run.

Based in Oakwood Grove, the donation allows the community centre to fund a youth worker for a whole year to deliver sport activities for young people at the centre.

More than 2,000 people visit the centre each month, with activities available for babies through to the elderly.

Gap director Marcos Campos said they were grateful for the funding.

He added: We are the only universal provision for young people in Warwick, other than after-school clubs, and funding like this is essential to allow us to continue providing this unique provision in the area.

We only charge members 60p a session, 1.20 for non-members you wouldnt get that anywhere else. Those who cant afford to pay, dont pay at all, we want everyone to be able to access the activities we offer here.

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Blindness charity returns as partner for Recency Run - Leamington Observer

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A look into four eye diseases that could lead to blindness – The Hindu

Thursday, February 23rd, 2017

The Hindu
A look into four eye diseases that could lead to blindness
The Hindu
A recent study from researchers at the Wilmer Eye Institute at Johns Hopkins University School of Medicine found that most Americans regard loss of eyesight as the worst ailment that could happen to them, surpassing such conditions as loss of limb ...

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