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Archive for the ‘Blindness’ Category

X Ambassadors Team Up With Foundation Fighting Blindness For Livestream – iHeartRadio

Wednesday, August 26th, 2020

X Ambassadors have always championed the visually impaired community, and on Thursday (August 20), brothers Casey and Sam Harris are partnering with Foundation Fighting Blindness and Two Blind Brothers for a benefit livestream to raise money for research dedicated to curing blindness.

Music to Our Eyes is set to take place at 7pm EST / 4pm PST on August 20 and will feature an acoustic performance from Casey and Sam that includes their hits Renegade, Unsteady, Hold You Down, and more, along with an interview. The event is free; however, those who are able to contribute a donation are encouraged to do so.

This partnership is particularly special to the brothers. Casey was born with with a rare genetic disease called Senior-Loken syndrome that affects the kidneys and retinas. As a result, he was born legally blind.

We are so excited and honored to be collaborating with Two Blind Brothers for this livestream conversation and acoustic performance with Sam and Casey Harris of X Ambassadors, Foundation COO Jason Menzo said in a statement. Together, we have this natural connection and unwavering commitment to providing hope and empowerment for the blind and visually impaired community.

Register to reserve your spot here.

Photo: Getty Images

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X Ambassadors Team Up With Foundation Fighting Blindness For Livestream - iHeartRadio

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Global Intraocular Lens (IOL) market size was USD 3159.3 million in 2018 and is projected to reach USD 5318.8 million by 2026, exhibiting a CAGR of…

Wednesday, August 26th, 2020

Trusted Business Insights answers what are the scenarios for growth and recovery and whether there will be any lasting structural impact from the unfolding crisis for the Intraocular Lens market.

Trusted Business Insights presents an updated and Latest Study on Intraocular Lens Market 2019-2029. The report contains market predictions related to market size, revenue, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing the key driving and restraining forces for this market, the report also offers a complete study of the future trends and developments of the market.The report further elaborates on the micro and macroeconomic aspects including the socio-political landscape that is anticipated to shape the demand of the Intraocular Lens market during the forecast period (2019-2029).It also examines the role of the leading market players involved in the industry including their corporate overview, financial summary, and SWOT analysis.

Get Sample Copy of this Report @ Intraocular Lens (IOL) Market Size, Share & Industry Analysis, By Type (Monofocal Intraocular Lens and Premium Intraocular Lens (Multifocal Intraocular Lens, Toric Intraocular Lens, and Others)), By Material (Polymethylmethacrylate (PMMA) and Foldable (Hydrophobic Acrylic, and Silicone & Collamer)), By End User (Hospitals & Ambulatory Surgery Centres, and Academic & Research Institutes) and Regional Forecast, 2020-2029 (Includes COVID-19 Business Impact)

The global Intraocular Lens (IOL) market size was USD 3,159.3 million in 2018 and is projected to reach USD 5,318.8 million by 2026, exhibiting a CAGR of 6.8% during the forecast period.

We have updated Intraocular Lens Market with respect to COVID-19 Impact.Inquire before buying

Cataract is one of the leading causes of blindness. Cataract removal is estimated to be the most common ophthalmic surgery across the globe. The intraocular lens is an artificial lens that is implanted in the eye during cataract procedures. Owing to strong government support and favorable reimbursement, more and more patients are undergoing cataract surgery. This has surged the adoption of an intraocular cataract lens. Initiatives to decrease the prevalence of cataract and an increasing number of NGOs providing free eye examinations and surgery are positively impacting the market.

The huge demand for the intraocular cataract lens has triggered the manufacturers to conduct research and development activities to provide advanced lenses that would help the patients with both near and distant vision. Many players are now focused on providing the trifocal, toric lens, and aspheric lenses that eliminate the need for wearing spectacles. For example, in December 2019, Johnson & Johnson Vision announced the U.S. launch of Tecnis Toric II, an intraocular cataract lens for correction of astigmatism in cataract patients. Furthermore, with the introduction of femtosecond laser-assisted cataract surgery, the demand for IOL is projected to increase by many folds.

MARKET DRIVERS

Increasing Number of Cataract Surgeries to Surge Demand for IOLCataract surgery is one of the most common ophthalmic procedures across the world. The rising prevalence of cataract and blindness associated with cataract has resulted in increasing the volume of cataract surgeries that are performed around the world. According to Eurostat, 4.5 million cataract procedures were performed in the European Union (EU) member states in 2016. This rising number of cataract procedures is anticipated to drive the IOL market revenue during the forecast period.

Furthermore, the rising prevalence of blindness and cataract is also one of the major reasons contributing to the expansion of the market. According to WHO, cataract is responsible for 47% of the world blindness and this is expected to favor the IOL market growth during the forecast period.

Launch of Several Government Initiatives for Cataract Elimination to Boost Market

The rising prevalence of cataract possesses an economic and health burden in many countries. This has resulted in the launch of various initiatives by the government for the elimination of cataracts. Vision 2020 is one such global initiative launched by the International Agency for the Prevention of Blindness (IAPB), with the aim to eliminate the main causes of avoidable blindness from the world. In addition, there is active participation by the government to achieve the target of Vision 2020 through reimbursement, eye checkup camps, and others. This is anticipated to accelerate the intraocular lens market growth in the forthcoming years.

SEGMENTATION

By Type Analysis

Monofocal Intraocular Lens Segment to Dominate Backed by Cost-effective NatureOn the basis of type, the market can be segmented into monofocal intraocular lens and premium intraocular lens. The premium intraocular lens segment is further classified into a multifocal intraocular lens, toric intraocular lens, and others. Monofocal intraocular lens segment is anticipated to dominate the IOL market share throughout the forecast period. Low pricing of monofocal lens compared to premium ones and favorable government reimbursement policies are the major factors attributable to the dominant share of monofocal IOLs.

On the other hand, premium IOLs have less penetration than monofocal IOLs. Also, many government-aided insurance policies do not cover the cost of premium IOLs and hence, the patient has to pay from their own pockets. Moreover, the advantages of the premium lenses over monofocal and the increasing preference for toric lenses are anticipated to drive the premium intraocular lens segment.

By Material Analysis

Foldable Segment to Witness a Remarkable Growth Owing to High Demand for Hydrophobic AcrylicBased on material, the market can be segmented into polymethylmethacrylate (PMMA) and foldable. The foldable segment is further divided into hydrophobic acrylic, hydrophilic acrylic, and silicone & collamer. The foldable segment is estimated to acquire a major portion of the market, primarily owing to its high refractive index and low water content, which is propelling its preference. Moreover, as intraocular cataract lenses are made from foldable material, they can be inserted through small incisions and are more widely used in cataract surgery. This intraocular lens market trend is anticipated to favor the growth of the foldable segment during the forecast period.Polymethylmethacrylate (PMMA) was the first material used for making the intraocular lens. Intraocular cataract lenses made from PMMA are significantly used in Europe and the rest of the world. This, coupled with the rising prevalence of cataract, is likely to favor the expansion of the polymethylmethacrylate (PMMA) segment during the forecast period.

By End User Analysis

Availability of Free Cataract Surgery to Drive the Growth of Hospitals & ASCs SegmentOn the basis of the end user, the market is segmented into hospitals & ambulatory surgery centers (ASCs), specialty clinics, and academic and research institutes. In terms of revenue, hospitals & ambulatory surgery centers segment accounted for the maximum portion of the market in 2018. An increase in the number of government hospitals and NGOs providing free of cost cataract surgeries, favorable health reimbursement, and increasing demand for daycare surgeries in hospitals are some of the major IOL market trends that are responsible for the growth of the segment.An increasing number of ophthalmic surgeons, a rising number of standalone eye clinics, and a significant increase in the number of cataract surgery in outpatient settings are expected to augment the expansion of the specialty clinics segment. Unite for Sight is an organization that provides financial and human resources to eye clinics around the globe. The increasing presence of such organizations to support eye clinics is also expected to boost the growth of this segment. The academic and research institutes segment is likely to propel owing to the active government efforts to train the ophthalmologists and an increasing number of doctors opting for fellowship programs to learn about the latest medical technologies.

REGIONAL ANALYSIS

North America generated a revenue of USD 892.9 million in 2018 and is projected to dominate the market throughout the forecast period. Technological advancement, such as custom cataract lens & Extended Depth of Focus (EDoF), and new product launches are the main reasons for the dominant North America IOL market share. According to the America Academy of Ophthalmology, 50 million people are projected to have a cataract in the U.S. by 2050. This is expected to favor the demand for an intraocular cataract lens in the U.S. during the forecast period.North America Intraocular Lens (IOL) Market Size, 2018

In Europe, the IOL market is anticipated to expand, owing to the increasing number of cataract surgery, rising adoption of femtosecond lasers for cataract surgery, and increased preference for toric lenses. According to Eurostat, in Germany, Italy, and Spain, the number of cataract surgeries performed per 1,000 populations in 2016 were 10, 9, and 7 respectively. This, coupled with the presence of various manufacturers in Europe, is expected to contribute to the growing demand for an intraocular cataract lens.

In Asia Pacific, the market is estimated to flourish owing to the rising prevalence of diabetes and cataract. Furthermore, increasing the volume of cataract surgery and strong government support are projected to boost the market for intraocular cataract lens. According to the National Programme for Control of Blindness and Visual Impairment (NPCB&VI), over 6.4 million surgeries were performed in India during 2016-2017. Such a high volume of cataract operations in India, China, and Japan are expected to augment the IOL market size in Asia Pacific. Increasing governmental efforts to improve the cataract surgical rate (CSR), rising number of ophthalmologists and rapid adoption of teleophthalmology are estimated to expand the intraocular lens market share in Latin America and the Middle East and Africa.

INDUSTRY KEY PLAYERS

Alcon and Johnson & Johnson Services, Inc. to Emerge as Leading PlayersIn terms of intraocular lens market revenue, Alcon and Johnson & Johnson Services, Inc. accounted for a leading position. Alcon had the highest IOL market share owing to the high demand and preference for AcrySof IOL. Increased efforts of the company to increase the penetration of premium lenses is the major reason for driving the growth of the company. The market shares of Johnson and Johnson Services, Inc. had increased drastically owing to the acquisition of Abbott Medical Optics in February 2017. Apart from this, increasing sales of the companys IOLs is anticipated to strengthen its position.

List Of Key Companies Profiled:

REPORT COVERAGE

Cataract is regarded as the leading cause of blindness in the world. Many programs are initiated to decrease the burden of cataract. This has resulted in increasing the number of cataract procedures and which, in turn, has surged the demand for an intraocular cataract lens. Furthermore, technological advancements, such as trifocal IOLs, accommodating IOLs, and others are expected to boost the adoption of IOL in the coming years. The report provides qualitative and quantitative insights on the global intraocular lens market trends and detailed analysis of market size & growth rate for all possible segments in the market.

An Infographic Representation of Intraocular Lens Market

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To get information on various segments, share your queries with us

The report provides a detailed analysis of the market and focuses on key aspects such as leading companies, competitive landscape, and product types. Besides, the report offers insights into the market trends and highlights key industry developments, such as mergers, acquisitions, and partnerships. In addition to the aforementioned factors, the report encompasses several key insights, such as the number of cataract surgery for key countries, prevalence of cataract for key countries, regulatory scenario for key countries, reimbursement scenario for key countries, new product launches, an overview of government cataract initiatives, etc.

Report Scope & Segmentation

Segmentation

By Type

By Material

By End User

By Geography

INDUSTRY DEVELOPMENT:

December 2019: Johnson & Johnson Vision announced the U.S. launch of Tecnis Toric II, an intraocular lens for the correction of astigmatism in cataract patients.

August 2019: Alcon announced the launch of AcrySof IQ PanOptix Trifocal Intraocular Lens in the U.S. The product is designed to deliver near and distance vision without the requirement of glasses.

February 2017: Johnson & Johnson Vision completed the acquisition of Abbott Medical Optics, which strengthened the companys position in the ophthalmic devices market.

Looking for more? Check out our repository for all available reports on Intraocular Lens in related sectors.

Quick Read Table of Contents of this Report @ Intraocular Lens (IOL) Market Size, Share & Industry Analysis, By Type (Monofocal Intraocular Lens and Premium Intraocular Lens (Multifocal Intraocular Lens, Toric Intraocular Lens, and Others)), By Material (Polymethylmethacrylate (PMMA) and Foldable (Hydrophobic Acrylic, and Silicone & Collamer)), By End User (Hospitals & Ambulatory Surgery Centres, and Academic & Research Institutes) and Regional Forecast, 2020-2029 (Includes COVID-19 Business Impact)

Trusted Business InsightsShelly ArnoldMedia & Marketing ExecutiveEmail Me For Any ClarificationsConnect on LinkedInClick to follow Trusted Business Insights LinkedIn for Market Data and Updates.US: +1 646 568 9797UK: +44 330 808 0580

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Global Intraocular Lens (IOL) market size was USD 3159.3 million in 2018 and is projected to reach USD 5318.8 million by 2026, exhibiting a CAGR of...

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Credential Theft Via Spoofed Login Pages Increase, Healthcare Top Target – HealthITSecurity.com

Wednesday, August 26th, 2020

August 25, 2020 -A newIRONSCALESreportfound a drastic increase in successful credential theft attempts sent through spoofed login pages and social engineering attacksduring the first half of 2020. And themost common recipients targeted with these attacks were those in the healthcare sector.

Researchers identified and analyzed fake login pages sent during the first half of the year, which are commonly used in support of spear-phishing campaigns and other hacks. Intotal, they identified more than 50,000 fake login pages, which spoofed login pages from over 200 prominent global brands.

Outside of healthcare, other leading recipients were those in financial services, government agencies, and technology industries.

The growing cyber threat of fake login pages [are] nefarious, yet often highly realistic looking pages [and] now a common tactic deployedby attackers seeking to obtain a persons login credentials to a legitimate website, such as a bank, email client, or social media site, among many other popular services, researchers explained.

The operation, commonly known as credential theft, is simple: target unsuspecting recipients with an email spoofing a trusted brand and persuade them via social engineering to insert their legitimate credentials, such asa username and password, into a fake login page either embedded within the body of an email or built into a phishing website, they added.

Once the victim has inputted their credentials, the hacker harvests the data to loginto real accounts and commence further illegal activities.

Just thisweek, the FBI and the Department of Homeland Security warned hackers were using voice phishing, or vishing, campaigns to build trust with victims, later duping them into logging intomaliciouswebsites made to appear astheir employers webpages.

Previous campaigns have spoofedZoom,Google,and MicrosoftOffice 365executive accounts, among others.

The IRONSCALES report found the top five brands with the most fake login pages are nearly identical to those that frequently have the most active phishing websites.

PayPal was the leading brand with 11,000 fake login pages, or 22 percent, closely followed by Microsoft with 9,500, or 19 percent and Facebook with 7,500, or 15 percent.eBaywas listed in fourth with 3,000pages, or 6 percent, with Amazon in last, with 1,500 pages, or 3 percent.

Other top brands with spoofed login pages included Aetna, Wells Fargo, Adobe, Apple, Tesco, and JP Morgan Chase, along with a host of others.

Although PayPal sits atop the list, the greatest risk may derive from the 9,500 Microsoft spoofs, as malicious Office 365, SharePoint and One Drive login pages put not just people but entire businesses a risk, researchers warned.

The researchers said its believed fake login pages are successful for two reasons. To start,malicious phishing emails containing spoofed logins often bypass technical controls like secure email gateways andSPAM filters, without requiring much investment in time, funds, or resources by the hacker.

Secondly, the attack's success may be due towhat is known as inattentional blindness or when an individual does not perceive the unexpected change hiding in plain sight.

Inattentional blindness became an internet sensation in 2012 when a video posted asking viewers how many white shirted players passed a ball. Intently focused on the task at hand, more than 50 percent of the viewers failed to recognize a woman in a gorilla suit in the middle of the picture, researchers wrote. Even people with phishing awareness training are susceptible to inattentional blindness.

Notably, about 5 percent of these attacks leveraging fake login pages were polymorphic in nature, where a hacker implements light but significant and often random change to an emails artifacts, such as its content, copy, subject line, sender name or template in conjunction with or after an initial attack has deployed.

An earlier IRONSCALES report showed 42percentof phishing attacks are polymorphic.The technique allows for the quick development of phishing attacks able to dupe signature-based email security tools that arent designed to recognize the modifications. As a result, a targeted victim could receive different versions of the same attack in their email account without being detected.

About 24 percent of the attacks spoofing Microsoft were polymorphic, with 314 permutations, followed by Facebook with 13 percent of permutation attacks or 160 permutations in total.

While we cannot say for certain why these brands have more permutations than others, we can make an educated guess that this occurred for one of two reasons:The security teams associated with these brands are actively looking to take down fake login pages, so attackers are forced to more frequently evolve the attack ever so slightly so to defeat human and technical controls, researchers mused.

These brands are a priority and or easy target for a certain hacking group(s), so there is more activity and therefore a need to constantly evolve in order to stay one step ahead of security teams, they added.

Microsoft has previously shared spear-phishing insights, which may help healthcare organizations better understand how these attacks work and mitigation techniques to harden enterprisedefenses.

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Credential Theft Via Spoofed Login Pages Increase, Healthcare Top Target - HealthITSecurity.com

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Global Inherited Retinal Diseases Market Will Generate Massive Revenue in Coming Years| Top Leaders-Fighting Blindness, FIGHTING BLINDNESS CANADA,…

Wednesday, August 26th, 2020

Inherited retinal diseases marketis expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses the market to account to an annual growth rate of 4.40% in the above-mentioned forecast period.

The major players covered in the inherited retinal diseases market report are American Society of Gene & Cell Therapy, Spark Therapeutics, Inc., Invitae Corporation., The Choroideremia Research Foundation Inc, American Council of the Blind, Foundation Fighting Blindness, Guide Dogs for the Blind, Inc., Fighting Blindness, FIGHTING BLINDNESS CANADA, Lighthouse Guild, The RDH12 Fund For Sight, Sofia Sees Hope, Retina International, Usher Syndrome Coalition, VisionServe Alliance among other domestic and global players. Market share data is available for global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.

Ask For Complimentary Sample PDF| Request Athttps://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-inherited-retinal-diseases-market

How does this market Insights help?

Europe is assumed to be the most lucrative inherited retinal disease market due to a relatively bigger prevalence of acquired retinal complications copulated with a higher treatment-seeking rate.

Global Inherited Retinal Diseases Market Scope and Market Size

Inherited retinal diseases market is segmented on the basis of type, treatment type and distribution channel. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

Based on type, inherited retinal diseases market is segmented into leber congenital amaurosis (LCA), retinitis pigmentosa, choroideremia, stargardts disease, and achromatopsia.

Inherited retinal diseases market has also been segmented based on treatment type such as gene therapy treatment, and symptomatic treatment.On the basis of distribution channel, the inherited retinal diseases market is segmented into hospital pharmacies, and retail pharmacies.

Inquiry For Customize Report With Discount at :https://www.databridgemarketresearch.com/inquire-before-buying/?dbmr=global-inherited-retinal-diseases-market

Global Inherited Retinal Diseases Market Drivers:

he growing awareness amongst the physicians and patients regarding the benefits associated with the usage of inherited retinal diseases has been directly impacting the growth of inherited retinal diseases market.

The swelling prevalence of the acquired retinal disorders is foreseen to push the growth of inherited retinal diseases treatment market. Expanding knowledge and treatment-seeking flow is anticipated to feed the germination of the inherited retinal diseases therapy business. Emphasizing knowledge of the inherited retinal disease surgery options and analysis of the condition is moreover awaited to magnify the growth of the inherited retinal disease surgery market.

The production businesses in the inherited retinal diseases market is moreover concentrating on the gene mutation-specific way for developing innovative outputs which is anticipated to accelerate the growth of inherited retinal diseases market. Numerous companies are contracting in collaborations, businesses to perform clinical experiments to promote acquired retinal disorder medication alternatives more efficiently. These certain mentioned factors are expected to drive the market growth in the forecasted period of 2020 to 2027.

To know more about the study,https://www.databridgemarketresearch.com/reports/global-inherited-retinal-diseases-market

About Data Bridge Market Research

An absolute way to forecast what future holds is to comprehend the trend today!Data Bridge set forth itself as an unconventional and neoteric Market research and consulting firm with unparalleled level of resilience and integrated approaches. We are determined to unearth the best market opportunities and foster efficient information for your business to thrive in the market. Data Bridge endeavors to provide appropriate solutions to the complex business challenges and initiates an effortless decision-making process.Data bridge is an aftermath of sheer wisdom and experience which was formulated and framed in the year 2015 in Pune. We ponder into the heterogeneous markets in accord with our clients needs and scoop out the best possible solutions and detailed information about the market trends. Data Bridge delve into the markets across Asia, North America, South America, Africa to name few.Data Bridge adepts in creating satisfied clients who reckon upon our services and rely on our hard work with certitude. We are content with our glorious 99.9 % client satisfying rate.

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What young people have to say about race and inequality in South Africa – The Conversation CA

Wednesday, August 26th, 2020

Meritocracy is the belief that holding power or success should be judged on peoples individual ability, rather than on wealth or social connections. At first glance, this appears to be a reasonable proposition. But the focus on individual merit becomes harder to fathom as one enters the messy world of structural inequality and discrimination.

As our research shows, ideologies of meritocracy and individualism create obstacles for collective action towards a more equal and just society. Our findings were published in the book Race in Education, the outcome of a thinktank on the effects of race at the Stellenbosch Institute for Advanced Study.

Using a methodology called Dreaming Workshops, our study explored how Grade 11 students, of around 16 and 17 years old, from different schools in the South African coastal city of Durban imagined race, racism and non-racialism in a utopian future.

Young South Africans are being socialised into a highly racialised society and experience severe disparities. Expecting them to eradicate racism without dismantling material inequalities is a deferral of adult responsibility. Mindful of this, we designed a study to listen to young peoples ideas, as opposed to looking to them for solutions.

The five schools that participated in this study, three government and two private, are located in a middle-class, formerly white area in Durban. The schools have, on average, a diverse but mostly middle-class student body, with some students travelling from townships to attend class. Under apartheid townships were poorly resourced and under-serviced residential spaces designated for people racialised as black. Each school in the study had approximately 20 students per class. One school markets itself as girls-only, one as boys-only, the other three are open to all genders.

Young people involved in the study were deeply aware of inequality. For them, reducing inequality was a priority if the country was to move towards a better future.

It is notable that non-racialism was not a concept volunteered by any of the students as a future ideal, despite it being a constitutional principle in South Africa. At present there is little clarity on the meaning of non-racialism. It is equated to a multiplicity of ideas, among them mobilisation against apartheid, multiracialism, multiculturalism, nation-building, and race-blindness.

What students did want eradicated from their utopia was racial discrimination and racism. The meanings they attached to race shifted depending on the conversation, for example, race when it related to racial quotas as opposed to race when it related to culture, identity or politics.

Racial identities played an important role in these young peoples sense of self. But some thought it is the weirdest thing ever that people sit in race groups during lunch breaks. They make sense of this by explaining that people sit with others who share their culture. Using race and culture as proxies for each other is very much part of the South African experience of racialisation.

The commitment to racial identities, however, was more complex than it first appeared. There was an uneasiness between accepting and feeling pride in racial identities, and not wanting them to count as measures of social value. They frequently vocalised a rejection of racial stereotypes and racism.

In each school, there were students committed to eradicating their own racist thoughts, who openly challenge parents and family members about racism and actively refused to essentialise their peers. Students felt a generational responsibility to challenge racial stereotypes.

They were also vehemently against race as a category in government policies. Arguments against racial quotas, such as broad-based black economic empowerment and affirmative action (race-based legislation aimed to redress past and current discriminations) were present in all the schools. As were statements that we need to get over blaming the past, or linking poverty with laziness, or refusing to recognise the role of privilege in individual achievement.

These sentiments reflected a socialisation process happening at schools, and in the family, that raised real tensions for young people. Many students were taught to believe that individual hard work pays dividends. Principles of individual success and meritocracy were well established in their homes, and valorised daily at their schools. Schools acutely focused on individual competition in sports and academic achievements, rewarding individual rather than collective effort.

The wiping out of the individual in favour of a group racial identity for employment and university entry appeared unfair and contradictory to the meritocratic values they were being taught to aspire to.

Read more: We need to unpack the word 'race' and find new language

These views were present in students who would be racialised as belonging to all four of South Africas racial categories, socially constructed in this country as black, Indian, Coloured and white.

Meritocratic arguments were also against the redistribution of wealth in South Africa. Taxing the rich was often seen as making the poor lazy. Here, class privilege was indiscernible from what would usually be thought of as a defence of white privilege.

In our view meritocratic sentiments are highly problematic in the context of structural inequality. In South Africa there is no equal playing field on which to justify individual merit.

It is not just race-blindness that we should guard against in South Africa; class-blindness too leads to a repetition of the status quo. Since structural inequalities fundamentally enable reproductions of racism this creates a complex dilemma for these students.

What does it mean to desire social justice and equality but refuse to give up any privileges?

This dilemma poses a challenge for education in South Africa. Certainly more frank and critical classroom conversations on race, class and culture are needed. More pressing is how to restructure schooling so that it is less focused on individual merit and reward.

This article is part of a series. Other authors include Barney Pityana, Gran Therborn, Nina Jablonski, George Chaplin and Njabulo Ndebele.

The three edited volumes of essays published by African Sun Media in 2018 (The Effects of Race, edited by Nina G. Jablonski and Gerhard Mar), 2019 (Race in Education, edited by Gerhard Mar), and 2020 (Persistence of Race, edited by Nina G. Jablonski) contain the complete representation of the projects scholarship.

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What young people have to say about race and inequality in South Africa - The Conversation CA

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Pranab Mukherjee’s renal parameters slightly deranged, continues on ventilator – United News of India

Wednesday, August 26th, 2020

More News27 Aug 2020 | 12:04 AM

New Delhi, Aug 26 (UNI) Border Security Force (BSF) on Wednesday apprehended seven Bangladeshi nationals who entered into Indian territory with the help of human traffickers near Mahendra Border Out Post (BoP) in Nadia district of West Bengal.

New Delhi, Aug 26 (UNI) With the national capital recoding more fresh infections compared to the recoveries, the recovery rate in the capital has witnessed a decline and went down under 90 per cent on Wednesday.

(Rptg, correcting Lead Para, Line 2)New Delhi, Aug 26 (UNI) To establish a transparent and comprehensive 'Performance Rating' System for its Consultants, Contractors and Concessionaires, the NHAI has developed a 'Vendor Performance Evaluation System'.

New Delhi, Aug 26 (UNI) A shocking incident came into picture on Wednesday wherein two brothers allegedly committed suicide together by hanging themselves at old Delhi's famous Chandni Chowk area as a result of financial crisis.

New Delhi, Aug 26 (UNI) To establish a transparent and comprehensive 'Performance Rating' System for its Consultants, Contractors and Concessionaires, the NHAI on Wednesday developed a 'Vendor Performance Evaluation System'.

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Pranab Mukherjee's renal parameters slightly deranged, continues on ventilator - United News of India

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Alimera Sciences Announces National Reimbursement Granted for ILUVIEN in the NetherlandsILUVIEN receives pricing and reimbursement approvals for both…

Wednesday, August 26th, 2020

ATLANTA, Aug. 26, 2020 (GLOBE NEWSWIRE) -- Alimera Sciences, Inc. (NASDAQ: ALIM) (Alimera), a pharmaceutical company that specializes in the development and commercialization of prescription ophthalmic pharmaceuticals, announces that Alimera Sciences Europe Limited, its Ireland-based European subsidiary received an add-on status for the pricing and reimbursement approval for ILUVIEN in the Netherlands from the Ministry of Health, effective September 1, 2020. Pricing and reimbursement approval was sought and secured by Alimeras distribution partner in France and the Benelux region, Horus Pharma S.A.S. (Horus). Horus is in the process of reviewing launch plans.

We are extremely pleased to have received this national coverage decision for ILUVIENs diabetic macular edema and non-infectious posterior uveitis indications in the Netherlands at the same time, said Rick Eiswirth, President and Chief Executive Officer of Alimera. Given Horuss impressive performance on the launch of ILUVIEN in France, we look forward to expanding distribution and sales in the Benelux region, and continuing to execute on our international growth strategy.

ILUVIEN is a sustained release intravitreal implant indicated in Europe for the treatment of vision impairment associated with chronic diabetic macular edema (DME) considered insufficiently responsive to available therapiesand for prevention of relapse in recurrent non-infectious uveitis affecting the posterior segment of the eye (NIPU).

We are genuinely pleased that for the second time, our collaboration with Alimera Sciences regarding ILUVIEN in Europe, has been fruitful, said Maja Lausevic, Chief Operating Officer, Horus Pharma. Access to ILUVIEN therapy is widely anticipated by ophthalmologists and patients in the Netherlands, and we are enthusiastic to provide this unique therapeutic solution to them and look forward to the official launch.

About ILUVIEN

http://www.ILUVIEN.com

The Companys primary product is ILUVIEN (fluocinolone acetonide intravitreal implant) 0.19 mg sustained release intravitreal implant, injected into the back of the eye. With its CONTINUOUS MICRODOSING technology, ILUVIEN is designed to release sub-microgram levels of fluocinolone acetonide, a corticosteroid, for 36 months, to reduce the recurrence of disease, enabling patients to maintain vision longer with fewer injections. ILUVIEN is approved in the U.S., Canada, Kuwait, Lebanon and the U.A.E to treat diabetic macular edema (DME) in patients who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in intraocular pressure. In 17 European countries, ILUVIEN is indicated for the treatment of vision impairment associated with chronic DME considered insufficiently responsive to available therapies. In March 2019, ILUVIEN received approval in the 17 countries under the Mutual Recognition Procedure for prevention of relapse in recurrent non-infectious uveitis affecting the posterior segment of the eye. The 17 European countries include the U.K., Germany, France, Italy, Spain, Portugal, Ireland, Austria, Belgium, Denmark, Norway, Finland, Sweden, Poland, Czechia, the Netherlands, and Luxembourg. The non-infectious posterior uveitis indication for ILUVIEN was launched in Germany and the U.K. in 3Q 2019. ILUVIEN is not approved for treatment of uveitis in the United States.

About Diabetic Macular Edema (DME)

DME, the primary cause of vision loss associated with diabetic retinopathy, is a disease affecting the macula, the part of the retina responsible for central vision. When the blood vessel leakage associated with diabetic retinopathy results in swelling of the macula, the condition is called DME. The onset of DME is painless and may go unreported by the patient until it manifests with the blurring of central vision or acute vision loss. The severity of this blurring may range from mild to profound loss of vision. The Wisconsin Epidemiologic Study of Diabetic Retinopathy found that over a 10-year period approximately 19% of people with diabetes included in the study were diagnosed with DME. All people with type 1 or type 2 diabetes are at risk of developing DME.

About Non-Infectious Posterior Uveitis(NIPU)

Posterior segment non-infectious uveitis is a chronic, inflammatory disease affecting the posterior segment of the eye, often involving the retina, and is a leading cause of blindness in developed and developing countries. It affects people of all ages, producing swelling and destroying eye tissues, which can lead to severe vision loss and blindness. Patients with NIPU are typically treated with systemic steroids, which are effective, but over time frequently lead to serious side effects, ranging from acne, weight gain, sleep and mood disorders to hypertension and osteoporosis that can limit effective dosing. Patients then often progress to steroid-sparing therapy with systemic immune suppressants or biologics, which also can have severe side effects, including an increased risk of cancer and infection. As a result, there remains a significant need for new therapies with improved efficacy, tolerability, and safety profiles to manage this disease.

About Alimera Sciences, Inc.

http://www.alimerasciences.com

Alimera Sciences is a pharmaceutical company that specializes in the commercialization and development of prescription ophthalmic pharmaceuticals. Alimera is presently focused on diseases affecting the back of the eye, or retina, because these diseases are not well treated with current therapies and affect millions of people in our aging populations. For more information, please visit http://www.alimerasciences.com.

AboutHorus Pharma S.A.S.

Founded in 2003 in France, Horus Pharma is an independent European laboratory specialized in ophthalmology. It has been recognized to date as one of the main innovative European actors in corneal reconstruction treatments, particularly in the areas of dry eye, scarring and keratoconus. Focused on patient safety, Horus Pharma has developed recognized expertise in the development of preservative-free formulations and product delivery systems. For further details, please visit http://www.horus-pharma.com.

Forward Looking Statements

This press release contains forward-looking statements, within the meaning of the Private Securities Litigation Reform Act of 1995, regarding, among other things, Alimeras expectations with respect to access to ILUVIEN for patients in the Netherlands. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual results to differ materially from those projected in its forward-looking statements. Meaningful factors which could cause actual results to differ include, but are not limited to, Horus ability to launch ILUVIEN in the Netherlands for both uveitis and DME, the willingness of healthcare professionals and organizations in the Netherlands to adopt ILUVIEN for the two indications and Horuss ability to get pricing and reimbursement in the remaining Benelux countries, Belgium and Luxembourg, as well as other factors discussed in the Risk Factors and Managements Discussion and Analysis of Financial Condition and Results of Operations sections of Alimeras Annual Report on Form 10-K for the year endedDecember 31, 2019 and Quarterly Reports on Form 10-Q for the quarters ended March 31, 2020 and June 30, 2020, which are on file with theSecurities and Exchange Commission(SEC) and available on theSECswebsite atwww.sec.gov.

All forward-looking statements contained in this press release are expressly qualified by the cautionary statements contained or referred to herein. Alimera cautions investors not to rely too heavily on the forward-looking statements Alimera makes or that are made on its behalf. These forward-looking statements speak only as of the date of this press release (unless another date is indicated). Alimera undertakes no obligation, and specifically declines any obligation, to publicly update or revise any such forward-looking statements, whether as a result of new information, future events or otherwise.

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Research to Prevent Blindness and Association of University Professors of Ophthalmology Announce 2021 Recipient of RPB David F. Weeks Award for…

Thursday, August 13th, 2020

Newswise SAN FRANCISCO, CA and NEW YORK, NY, August 13David Williams, PhD, has been selected as the 2021 RPB David F. Weeks Award for Outstanding Vision Research (Weeks Award). The Weeks Award, funded through the generosity of Research to Prevent Blindness (RPB), an anonymous donor, and the Association of University Professors of Ophthalmology (AUPO), annually recognizes and celebrates an excellent vision researcher. The award carries the name of David F. Weeks, former President and Chairman of RPB, in honor of his contributions to the field of vision research. Dr. Williams will receive his award and deliver a presentation during the AUPO 2021 Annual Meeting in February.

Dr. Williams holds the position of William G. Allyn Professor of Medical Optics at the University of Rochester. David Williams contributions to understanding the optical factors in vision have been profound. The impact of his research establishes him as one of the outstanding visual scientists in his generation, and his creative ideas for future vision research have the potential to ultimately unlock the discoveries needed to cure blindness, said David A. DiLoreto, Jr., MD, PhD, Chairman for the Department of Ophthalmology at the University of Rochester.

AUPO President, David Quillen, MD shared, We are thrilled to recognize Dr. Williams with the Weeks Award. Dr. Williams is one the world's leading experts on human vision. He and his team have transformed ophthalmology and visual science through the development and implementation of the first adaptive optics system for the eye. This work has resulted in unprecedented developments in patient care including wavefront-guided refractive surgery and exquisite retinal imaging. It is a remarkable story that will continue to advance our understanding of the eye and vision.

Dr. Williams work is the kind of ground-breaking research that fulfills Mr. Weeks vision for the advancement of vision science via his work at RPB and his advocacy activities that were key to the creation of the National Eye Institute, said Brian F. Hofland, PhD, President of Research to Prevent Blindness. On behalf of RPB, I extend my sincerecongratulationsto Dr. Williams on all of his past accomplishments, and I look forward to his future innovations.

For more information on the RPB David F. Weeks Award for Outstanding Vision Research, visit the AUPO website.

About Research to Prevent Blindness

Research to Prevent Blindness (RPB) is the leading nonprofit organization supporting eye research directed at the prevention, treatment or eradication of all diseases that damage and destroy sight. As part of this purview, RPB also supports efforts to grow and sustain a robust and diverse vision research community. Since it was founded in 1960 by Dr. Jules Stein, RPB has awarded more than $373 million in research grants to the most talented vision scientists at the nations leading medical schools. As a result, RPB has been associated with nearly every major breakthrough in the understanding and treatment of vision loss in the past 60 years. Learn more atwww.rpbusa.org.

About Association of University Professors of Ophthalmology

The Association of University Professors of Ophthalmology (AUPO) was founded in 1966 as a nonprofit organization dedicated to research and education. AUPO is the voice of academic ophthalmology through the promotion of medical education, research, and patient care in ophthalmology, and accomplished by providing a forum for discussion of mutual issues facing departments/divisions of ophthalmology in the United States and Canada. For more information, visit aupo.org.

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X Ambassadors Teams up with Foundation Fighting Blindness and Two Blind Brothers to Launch Music to our Eyes Exclusive Livestream Music Series -…

Thursday, August 13th, 2020

X Ambassadors' keyboardist, Casey Harris, was born with the rare genetic disease, Senior-Loken syndrome, which affects his kidneys and retinas. The acoustic performance by brothers Sam and Casey Harris will feature their top hits including, Renegade, Unsteady, Hold You Down, and Belong. In between sets, Jason Menzo, chief operating officer at the Foundation Fighting Blindness, will interview Sam and Casey about their experiences with vision loss and discuss their commitment to creating music that celebrates diversity and belonging. Event registration is free, but attendees will have the opportunity to contribute, as all net proceeds will go towards the Foundation's mission.

"We are so excited and honored to be collaborating with Two Blind Brothers for this livestream conversation and acoustic performance with Sam and Casey Harris of X Ambassadors," says Jason Menzo, COO at the Foundation. "Together, we have this natural connection and unwavering commitment to providing hope and empowerment for the blind and visually impaired community."

For more information and to register for a reminder about the event, visit: https://bit.ly/3ihTkda

About the Foundation Fighting BlindnessEstablished in 1971, the Foundation Fighting Blindness is the world's leading private funding source for retinal degenerative disease research. The Foundation has raised more than $800 million toward its mission of accelerating research for preventing, treating, and curing blindness caused by the entire spectrum of retinal degenerative diseases including: retinitis pigmentosa, age-related macular degeneration, Usher syndrome, and Stargardt disease. Visit FightingBlindness.org for more information.

Media Contacts:Chris Adams Vice President, Marketing & Communications [emailprotected] (410) 423-0585

SOURCE Foundation Fighting Blindness

http://www.FightBlindness.org

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Lifting the burden of cornea blindness through donation – The Star, Kenya

Thursday, August 13th, 2020

Cornea is the clear tissue covering the front of the eye and is the main focusing part of the eye. If it becomes cloudy or scarred, say, due to an eye injury or infection, vision is reduced or lost because the scar tissue scatters the light passing through the cornea.

This is known as cornea opacity, which is considered a major public health problem. According to the World Health organisation, there are at least 2.2 billion people with vision impairment that could have been prevented or has yet to be addressed. Among these, those suffering from cornea opacities are about 4.2 million.

In Kenya, according to the annual report for the year 2018 by the Kenya Society for the Blind, there are about 350,000 people who are blind while another 750,000 are visually impaired. The Lions SightFirst Eye Hospital which is the biggest eye hospital in East Africa reports that cornea opacities contribute to 19% of blindness cases.

One of the ways to treat cornea opacity is with a cornea transplant, this can restore vision. Cornea transplant involves a surgical procedure which replaces a disc-shaped segment of an impaired cornea with a similarly shaped piece of healthy donor cornea. Though we do not have nationwide studies in Kenya it can be estimated that those in need of cornea transplant exceed 50,000 cases.

Journey of cornea transplant in Kenya

This year as the world marks the World Organ Donation Day, we chose to focus on cornea transplant in Kenya which is largely led by Lions SightFirst Eye Hospital. According to the experts in the hospital, there are competent surgeons in Kenya who are able to undertake the required surgery [known as Keratoplasty] to restore cornea opacity and surgical facilities are available for the procedure, but there has been shortage of donor corneas to meet the demand.

As a way of addressing this gap between supply and demand, there was established the first ever eye bank in East and Central Africa in the year 2007 which was named after its chief sponsor Lion Kanubhai Babla. The eye bank was established at the Lions SightFirst Eye Hospital. The eye bank which is still in operation obtains, medically evaluates and distributes donated corneas for use in transplantation, research and medical education.

Before the establishment of this eye bank, cornea transplants were done with donor corneas from abroad. The costs involved to either travel abroad for the surgery or to procure the corneas from abroad were too high for the majority of patients to afford thus remaining blind for the rest of their lives. The eye bank started, and still does, facilitating cornea transplant at minimal cost to the needy and deserving patients.

Currently the Lion Kanubhai Babla Eye Bank at Lions Eye Hospital is fundamental to the obtainment, screening and storage of donated eye tissue used for cornea transplant. The eye bank team provides a 24- hour information and retrieval service 365 days a year and it provides these services throughout the country but with priority to the needy especially students so that they can continue with their studies uninterrupted.

Where the eye bank gets cornea for transplant

Lion Kanubhai Babla Eye Bank relies on voluntary donation of corneas and only the corneas are obtained not the whole eyeball. Kenya performs about 200 cornea transplants annually with donations coming from non-native communities. This is mainly associated with cultural and religious beliefs surrounding death among the indigenous Kenyan communities. While pledging to become a donor, there is no monetary compensation given or any other form of incentives, either to the donor or to the family.

The time required to obtain cornea is 6-8 hours after death and it is stored immediately to avoid damage. The Lions Eye bank collaborates with eye bank ambassadors and other hospitals to assist in proper preservation of the donor bodies before the eye bank specialists can get to the harvesting point. Cornea can be removed at hospital or even at residence or wherever death occurs.

Only people above the age of 18 years are allowed to pledge their cornea because this is the consent age in Kenya. However, it is not suitable to transplant a cornea from an older donor to a young patient. A potential donor pledges at the Lions eye bank to give their cornea when they die. However, the family needs to give consent upon the death of the donor. It is therefore important that the donor notifies their family and has them understand the reason and implications of the decision. This prevents contention when the cornea needs to be obtained.

As the decision for eye donation is made by the family members when a death occurs, the commitment and involvement of the whole family is required. Eye donation will work best, when it becomes a tradition in every Kenyan family and a part of our culture, irrespective of religion and other aspects.

Elizabeth Mbugua and Stephen Rukwaro (Lions SightFirst Eye Hospital)

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Blindness is inventive and thoroughly engrossing a real light in our current darkness – iNews

Thursday, August 13th, 2020

While other theatres remain closed, the Donmar Warehouse in Covent Garden welcomes audiences four times a day to experience a socially distanced sound installation. After following a strict anti-Covid drill (distanced queuing and seating, sanitiser, face masks), people hear a recording over headphones of Juliet Stevenson narrating an adaptation of the Portuguese Nobel laureate Jos Saramagos 1995 novel Blindness.

Saramagos story is simple but, like Albert Camuss The Plague, even more resonant in the current climate. One day, a driver stops his car at some traffic lights because he cant see any more. It is soon apparent that this form of blindness is contagious and, within days, the whole city, then the country, is infected.

Caught up in the chaos of the inexplicable epidemic is an unnamed eye doctor, his strong-willed wife and some of their patients. As the Government uses the army to herd the sightless victims into a disused asylum for quarantine, it becomes clear the doctors wife is the only person who retains her sight.

Adapted by playwright Simon Stephens into a 70-minute narrative monologue, in which Stevenson also plays the doctors wife, Blindness shows how quickly society can disintegrate when an epidemic renders citizens vulnerable. The strong terrorise the weak; the government fails to control the sickness; but there is hope in collective solidarity despite acute adversity.

Loss of sight can mean a better perception rather than a disability, and this version of the novel is alive to current resonances. The announcements of the Government recall not only the injunctions of various military juntas, but also strike closer to home, talking glibly of a curve of resolution.

At other moments, the horror of a minister losing their sight during a press conference goes hand in hand with the feeling that often these events are designed to blind you with untruths. Likewise, the repeated notion of individual responsibility roots this universal fable in an Anglo-Saxon context.

A great part of the show is experienced in darkness, and Ben and Max Ringhams immersive binaural sound design allows Stevenson to whisper in your ear or rush across a room, shouting in the distance. She begins coolly and becomes increasingly desperate. The feeling of intimacy and reality iscompelling.

Walter Meierjohanns production also uses Lizzie Clachans design and Jessica Hung Han Yuns multi-coloured strip lighting to brilliant effect, all of which remind us of the importance of sight.

Blindness is inventive and thoroughly engrossing a real light in our current darkness.

To 22 August (020 3282 3808)

THEARTSDESK.COM

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Theatre review: Blindness – Metro Newspaper UK

Thursday, August 13th, 2020

REVIEWDonmar Warehouse, London

RIGHT now, it seems a small miracle that this penetrating, inventive piece of theatre exists at all. That it also speaks so eloquently to our Covid-afflicted present and our common humanity is an exhilarating testament to the power and necessity of art not least at times of crisis.

Its adapted from Jose Saramagos novel, in which a city is stricken by an epidemic of blindness. A bright, white sightlessness descends without warning and its virulently contagious. The rudderless government loses control (sound familiar?), society disintegrates and new hierarchies emerge, with the uninfected free to exploit and abuse. But there is hope, too, of rebuilding something better.

Written by Simon Stephens, Walter Meierjohanns production shrewdly embraces social distancing safeguards. Masks must be worn throughout, ramping up the sweaty, claustrophobic intensity. There are no live actors; the narrative unspools through binaural headphones, delivered by Juliet Stevenson as a doctors wife who escapes the virus and becomes a horrified witness and reluctant hero. The audience is scattered around the bare stage. Overhead hang angular rods of light, which rise and fall, changing colour, before blinking out, leaving us in absolute darkness.

Its an unnervingly intimate experience, with Stevensons feverish voice so close you can almost feel her hot breath on your skin. The sense of disorientation scarcely abates when the lights come up and you find yourself surrounded by masked figures, too far away to touch.

Its not always easy to endure. But at this particular historical moment, it is a unique and unforgettable achievement.

Blindness runs until August 22. donmarwarehouse.com

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Justifiable Bullishness Or Is It Willful Blindness? – Seeking Alpha

Thursday, August 13th, 2020

Currently, there is much bullish commentary suggesting stocks can only go higher from here. Is the bullishness in the markets justifiable, or is it willful blindness?

John Stoltzfus, CIO of Oppenheimer, is clearly in the bullish camp:

We remain very bullish on this market. Youre going to see money beginning to further move out of the bond market, and it makes all the sense in the world to be positioned in equities.

This seems a little optimistic given the amount of money that has already flooded into the 5-largest mega-cap stocks which have accounted for a bulk of this years market returns.

Nonetheless, it is an interesting question.

From the bulls viewpoint the focus has been the ability for these companies to grow earnings.

The bearish view is the problem with valuations.

As noted in COT Positioning Back To Extremes, the Nasdaq set repeated new highs in 2020, which is astonishing given the depth of the economic recession. To wit:

While the S&P 500 is primarily driven higher by the largest 5-market capitalization companies, it is the Nasdaq that has now reached a more extreme deviation from its longer-term moving average.

Moving averages, especially longer-term ones, are like gravity. The further prices become deviated from long-term averages, the greater the gravitational pull becomes. An average requires prices to trade above and below the average level. The risk of a reversion grows with the size of the deviation.

The Nasdaq currently trades more than 23% above its 200-dma. The last time such a deviation existed was in February of this year. The Nasdaq also trades 3-standard deviations above the 200-dma, which is another extreme indication.

The immediate conclusion is the drive higher in the markets is a function of massive amounts of liquidity being injected into the financial markets by the Federal Reserve. As shown below that was certainly the case during March and April.

However, since then the tapering of the liquidity injections by the Fed has been marked as the slowing uptake of the various programs reduced demand.

While there is indeed truth to the Feds impact on the market, it is not solely responsible for the dislocation of prices from the underlying fundamentals.

As shown, the decline in fundamentals didnt start during the pandemic. The decline in earnings started in early 2019 as economic growth slowed, and accelerated during the pandemic. However, during that same period stock prices rose, which is almost entirely attributable to valuation expansion.

E*Trade recently released survey data which showed that despite the market plunge in March, bullish sentiment has returned:

You get the idea. Just one quarter after panic selling lows, investors are once again back in the pool. Despite the economy just printing a nearly 40% decline in Q2, and earnings having dropped by nearly 40% from their peak, the dumb money is back to chasing stocks.

In particular, not only are retail investors chasing stocks, they are doing it with increased leverage by using options. As noted by CNBC recently:

Investors have reentered the market at a record rate following the coronavirus-induced sell-off in March, and as traders look to profit, options volume has soared to an all-time high.

The average daily value of options traded has exceeded shares for the first time, with July single stock options volumes currently tracking 114% of shares volumes.

In other words, the options market is now larger than the shares market.

We have seen record lows in the Put/Call ratio three times in 2020. All three lead to corrections.

Willful blindness, also known as willful ignorance or contrived ignorance, is a term used in law. Being willfully blind describes a situation in which a person seeks to avoid civil or criminal liability for a wrongful act by keeping themselves unaware of the facts that would render them liable or implicated.

Although the term was originally used in legal contexts, the phrase willful blindness has come to mean any situation in which people avoid facts to absolve themselves of their liability.

Willful blindness is most prevalent in the financial markets. Investors regularly dismiss the facts which run contrary to their current opinion. In behavioral investing terms this is also known as confirmation bias.'

As markets rise, investors take on exceedingly more risk with the full knowledge that such actions will have a negative consequence. However, that negative consequence is dismissed by the fear of missing out, or rather F.O.M.O.

As greed overtakes fear, investors become more emboldened as rising markets reinforce the conviction that this time is different. Ultimately, when the negative consequence eventually occurs, instead of taking responsibility for their actions, they blame the media, Wall Street, or their advisor.

This currently where we are in the markets today.

Investors know there is a rising risk of loss, but, they are willfully ignoring the facts and and piling into risk because the narrative has simply become fundamentals dont matter. In 2020, investors are again chasing growth at any price and rationalizing overpaying for growth.

Such makes the mantra of using 24-month estimates to justify paying exceedingly high valuations today, even riskier.

This is also where there is the greatest disparity between growth and value on record.

There are two critical takeaways from the graph above:

In other words, there is high probability that investors chasing growth are going to pay a heavy price in the future..

The problem, as discussed in Insanely Stupid, the ability for stocks to continue to grow earnings at a rate to support high valuations will be problematic. Such is due to rising debts and deficits which will retard economic growth in the future. To wit:

Before the Financial Crisis, the economy had a linear growth trend of real GDP of 3.2%. Following the 2008 recession, the growth rate dropped to the exponential growth trend of roughly 2.2%. Instead of reducing the debt problems, unproductive debt, and leverage increased.

The COVID-19 crisis led to a debt surge to new highs. Such will result in a retardation of economic growth to 1.5% or less.

Slower economic growth, combined with a potential for higher taxes, increases the probability that risk may well outweigh reward at this juncture.

Such doesnt mean that stocks cant go higher in the near term, and despite some wiggles along the way, it is quite likely they will simply because of momentum and lots of bullish bias.

Weve often noted that during times of unhealthy market environments, when fewer than 60% of stocks can hold above their 200-day averages, that periods of high optimism tend to lead to below-average forward returns.

Were seeing that now, to a historic degree. Since weve been tracking this data, just over 20 years, there has never been a day when Dumb Money Confidence was at or above 80% while fewer than 60% of stocks in the S&P 500 were trading above their 200-day averages. Until now. Sentiment Trader

The problem of eternal bullishness is it leads to the willful blindness of risks, rather than having a healthy respect for, and recognition of, those risks. This leads to the unfortunate problem of being all-in on every hand which has a devastating consequence when a mean reverting event occurs.

Our job as investors is to navigate the waters within which we currently sail, not the waters we think we will sail in later. Higher returns come from the management of risks rather than the attempt to create returns by chasing markets.

I recently quoted Robert Rubin, former Secretary of the Treasury, in This Is Nuts, as it defined our philosophy on risk.

As I think back over the years, I have been guided by four principles for decision making. The only certainty is that there is no certainty. Second, every decision, as a consequence, is a matter of weighing probabilities. Third, despite uncertainty, we must decide and we must act. And lastly, we need to judge decisions not only on the results but also on how we made them.

Most people are in denial about uncertainty. They assume theyre lucky, and that the unpredictable can be reliably forecasted. Such keeps business brisk for palm readers, psychics, and stockbrokers, but its a terrible way to deal with uncertainty. If there are no absolutes, all decisions become matters of judging the probability of different outcomes, and the costs and benefits of each. Then, on that basis, you can make a good decision. Robert Rubin

It should be evident that an honest assessment of uncertainty leads to better decisions.

The problem with Eternal Bullishness and Willful Blindness is that the failure to embrace uncertainty increases risk, and ultimately loss.

We must be able to recognize and be responsive to changes in underlying market dynamics. If they change for the worse, we must be aware of the inherent risks in portfolio allocation models. The reality is that we cant control outcomes. The most we can do is influence the probability of specific outcomes.

Focusing on risk not only removes willful blindness from the process, it is essential to capital preservation and investment success over time.

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Editor's Note: The summary bullets for this article were chosen by Seeking Alpha editors.

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Blind teen captivates social media with reading and writing lesson: ‘This blows my mind’ – Yahoo Sports

Thursday, August 13th, 2020

A British TikToker has captivated social media with a simple explanation of how she both creates and consumes online content as a blind person.

Gracie Marsh, a 19-year-old disability advocate from England who went blind at age 14 due to Septo-optic dysplasia, shared a now-viral video on July 28 explaining how she operates her BrailleNote HumanWare Touch+.

Marsh demonstrates how the tablet, which allows those with visual impairments to read and write with ease, functions as she walks viewers through the keyboards nine main buttons the backspace, enter and space bars, as well as the six keys representing the six dots that make up the braille system.

The device also comes equipped with a touchscreen, which Marsh says is particularly useful for teachers and sighted peers.

Her insightful video has since racked up over 1.5M views on TikTok alone, plus 2.2M more on Twitter, along with tons of comments from viewers who were utterly impressed with the technology.

This is [a] true technological masterpiece! wrote one user.

This was really interesting to learn! Thanks for sharing with us, commented another.

This blows my mind, said a third.

Marsh, who was born with multiple chronic illnesses that have caused her to need a wheelchair, feeding tube and catheter, told In The Know that she started making TikToks for entertainment earlier this year before pivoting into disability awareness content after one of her videos went viral with over 450K views in June.

[A TikTok] where I did my makeup as a blind person kind of blew up, so I decided totry and build a bigger platform, Marsh, who now boasts over 28K followers, told In The Know.

With content ranging from rating her main diagnoses to how she uses an iPhone to how she dreams, Marsh says that her videos have been generally well-received.

She does, however, still occasionally get nasty or misinformed comments, including some that allege shes faking her condition.

Its been really positive overall, but I have received some comments questioning my blindness, she told In The Know. How are you blind if youre reading these comments? et cetera, even though thats been explained in many of my TikToks!

Ultimately, Marsh hopes that her informative and often humorous videos can serve to dispel stigmas surrounding the visually impaired and show the world exactly what shes capable of.

I think Id just like people to know that blindness, and disability in general, doesnt mean that individuals cant advocate for themselves, participate in normal activities and be independent, she said. Id like people to stop underestimating me and the disabled community as a whole!

These are the best tech gifts under $100:

If you enjoyed this article, read about TikToker Chrissy Marshall, who uses her experience as a deaf woman to educate millions.

More from In The Know:

Starbucks is opening its first sign language store in Japan

Deaf, transgender model Chella Man shares how to be a better ally for people with disabilities

Netflixs new show, Love on the Spectrum, highlights the dating lives of people with autism

Blind skateboarder Ryusei Ouchi has never let his disability hold him back

The post Teen reveals how shes able to read and type as a blind person appeared first on In The Know.

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Ocugen Receives Fourth FDA Orphan Drug Designation for the Same Product, OCU400 (AAV-NR2E3) Gene Therapy, for the Treatment of Another Key Inherited…

Thursday, August 13th, 2020

MALVERN, Pa., Aug. 10, 2020 (GLOBE NEWSWIRE) -- Ocugen, Inc. (NASDAQ: OCGN), a biopharmaceutical company focused on discovering, developing, and commercializing transformative therapies to cure blindness diseases, today announced the U.S. Food and Drug Administration (FDA) granted the fourth Orphan Drug Designation (ODD) for OCU400 in the treatment of PDE6B gene mutation-associated retinal diseases. Retinitis Pigmentosa (RP) caused by PDE6B mutation is an inherited retinal dystrophy that leads to blindness by midlife and is characterized by the progressive loss of photoreceptors, with or without the loss of retinal pigment epithelium cells. At least one mutation in the PDE6B gene has been found to cause autosomal dominant congenital stationary night blindness, which is characterized by the inability to see in low light.

Ocugens Modifier Gene Therapy Platform offers a unique approach in ophthalmology by addressing multiple diseases with a single product. A novel gene therapy product candidate, OCU400 has the potential to be broadly effective in restoring retinal integrity and function across a range of genetically diverse inherited retinal diseases. It consists of a functional copy of a nuclear hormone receptor (NHR) gene, NR2E3, delivered to target cells in the retina using an adeno-associated viral vector. As a potent modifier gene, expression of NR2E3 within the retina may help reset retinal homeostasis and potentially offer longer benefit, stabilizing cells and rescuing photoreceptor degeneration and vision loss. In pre-clinical studies, OCU400 has demonstrated improved vision signals in the retina where Electroretinogram response reveals rescue under both Scotopic (dim-lit) as well as Photopic (well-lit) conditions. The Company believes targeting multiple diseases with one product could also offer a smoother regulatory pathway and the ability to recover development costs over multiple therapeutic indications. Ocugen is planning to initiate two parallel Phase I/II clinical trials next year targeting two unique IRDs.

Following up on recent announcement of an ODD for RHO mutation-associated retinal degeneration and previous ODDs for both NR2E3 and CEP290 mutation-associated retinal degeneration, the ODD for PDE6B gene mutation-associated retinal degeneration continues to support Ocugens breakthrough modifier gene therapy platforms potential to treat multiple blindness diseases with a single product. RP is a group of heterogenic inherited retinal diseases associated with over 150 gene mutations, affecting over 1.5 million individuals worldwide. In addition, ~40% of RP patients cannot be genetically diagnosed, confounding the ability to develop personalized RP therapies. Traditional gene therapy or gene editing approaches may require more than 150 products to rescue these patients from vision loss. OCU400, a single product candidate, has potential to address broad-spectrum RP.

As principal investigator of numerous major clinical trials developing new medical and surgical treatments for retinal disorders, I have been on the cutting-edge of many new ophthalmology treatments. I am very encouraged by the potential for OCU400 given the uniqueness of Ocugens Modifier Gene Therapy Platform and the fact that FDA has issued four ODDs for this product. I look forward to Ocugen commencing clinical trials for OCU400 next year and the potential of helping patients by restoring retinal integrity and function across a range of genetically diverse inherited retinal diseases including broad-spectrum RP, said Carl D. Regillo, M.D.,F.A.C.S., member of Ocugens Retina Scientific Advisory Board and Professor of Ophthalmology at the Sidney Kimmel Medical College at Thomas Jefferson University, Chief of the Retina Service at Wills Eye Hospital and founder and former director of the Wills Eye Clinical Retina Research Unit in Philadelphia.

I am thrilled to announce our fourth ODD for OCU400 from the FDA after announcing our third ODD for RHO mutation-associated retinal degeneration just a few days ago. With no approved treatments that slow or stop the progression of RP, we are dedicated to driving the development of our Modifier Gene Therapy Platform forward and potentially addressing the unmet need of multiple gene mutations, including mutations in the PDE6B gene with only one product, said Dr. Shankar Musunuri, Chairman, Chief Executive Officer and Co-Founder of Ocugen.

The FDA Office of Orphan Products Development grants orphan designation for novel drugs or biologics that treat a rare disease or condition affecting fewer than 200,000 patients in the U.S. Orphan designation qualifies the sponsor of the drug for various development incentives of the Orphan Drug Act, including a seven-year period of U.S. marketing exclusivity, tax credits for clinical research costs, clinical research trial design assistance, the ability to apply for annual grant funding and waiver of Prescription Drug User Fee Act filing fees.

About OCU400OCU400 (AAV-hNR2E3) is a novel gene therapy product candidate with the potential to be broadly effective in restoring retinal integrity and function across a range of genetically diverse inherited retinal diseases. It consists of a functional copy of a nuclear hormone receptor gene, NR2E3, delivered to target cells in the retina using an adeno-associated viral vector. As a potent modifier gene, expression of NR2E3 within the retina may help reset retinal homeostasis, potentially stabilizing cells and rescuing photoreceptor degeneration and vision loss.

About Ocugen, Inc.Ocugen, Inc. is a biopharmaceutical company focused on discovering, developing, and commercializing transformative therapies to cure blindness diseases. Our breakthrough modifier gene therapy platform has the potential to treat multiple retinal diseases with one drug one to many and our novel biologic product candidate aims to offer better therapy to patients with underserved diseases such as wet age-related macular degeneration, diabetic macular edema and diabetic retinopathy. For more information, please visit https://ocugen.com/.

Cautionary Note on Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995, which are subject to risks and uncertainties. We may, in some cases, use terms such as predicts, believes, potential, proposed, continue, estimates, anticipates, expects, plans, intends, may, could, might, will, should or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. Such statements are subject to numerous important factors, risks and uncertainties that may cause actual events or results to differ materially from our current expectations. These and other risks and uncertainties are more fully described in our periodic filings with the Securities and Exchange Commission (the SEC), including the risk factors described in the section entitled Risk Factors in the quarterly and annual reports that we file with the SEC. Any forward-looking statements that we make in this press release speak only as of the date of this press release. Except as required by law, we assume no obligation to update forward-looking statements contained in this press release whether as a result of new information, future events or otherwise, after the date of this press release.

Corporate Contact:Ocugen, Inc.Sanjay SubramanianChief Financial OfficerIR@Ocugen.com

Media Contact:LaVoieHealthScienceEmmie Twomblyetwombly@lavoiehealthscience.com+1 857-389-6042

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Letters to the editor | The Pittsburgh Jewish Chronicle – thejewishchronicle.net

Thursday, August 13th, 2020

Blessing of sight often overlookedIts very easy to take our senses for granted. As Joni Mitchell says, you dont know what youve got till its goneThe blessing of sight is often overlooked. However, in an instant, it can vanish. David Rullos interview with Sandy Greenberg in Hello Darkness, My Old Friend (July 31), recounting the friendship between Greenberg and Art Garfunkel, is a cautionary piece, and one that personally struck close to home: Sandy Greenberg was a childhood friend to many in my family and, after all, Buffalo is a big small town.

Three years ago during an annual ophthalmological exam, I was diagnosed with narrow angles, a condition that can lead to glaucoma and sudden blindness. We are incredibly fortunate that treatments and surgery are now available to correct this otherwise disastrous and life-changing condition. Yet, according to the American Academy of Ophthalmology, of the large number of adults who report having eye problems (64%), only 13% of them have seen a doctor for an eye exam. The 2020 End Blindness prize that will award $3 million to the deserving team needs to focus on public awareness of necessary ophthalmological yearly exams, especially for those 40 years and older, to correct what is now a preventable blindness condition.

Dori OshlagSquirrel Hill

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Notable events ignored in Chronicle featureI have been mystified for some time by the events that the Center for Israel Education provides the Chronicle (This Week in Israeli history, ongoing). I wondered why the dates were not notable in Jewish history, rather than being limited to Israeli history. How, in fact, can the two be separated?

They cant as a regular reading of the feature clearly demonstrates. The CIE notes, for example, the Aug. 4 publication of an article by Mordecai Kaplan laying the groundwork for Reconstructionist Judaism. How, one might ask, is that related to Israel history? Ah, the item cleverly closes with what no doubt is a barely noticed phrase Kaplans article includes Zionism as a key component.

In addition to learning about Kaplans article, your readers might if they found it of the slightest interest have learned the birthdate of an obscure Israeli politician, and the date of death of an equally obscure composer. What they would not have read was one word about one of the great tragedies of Jewish history: the expulsion of the Jews from Spain. Apparently that lacked a sufficient connection to Israel to be worthy of the CIEs attention.

But that shouldnt have missed the Chronicles attention too. Surely your readers are worthy of a more a comprehensive look at Jewish history than what the CIE can conceive of.

The Bialystok Ghetto uprising began on Aug. 20, 1943, and Leopold Zunz was born on Aug. 10, 1794. Since neither is amenable to an easy connection to Israeli history, I assume the CIE will overlook them both. Will the Chronicle do the same?

The CIE may be a useful resource for the Chronicle, but it certainly isnt a sufficient one. Finding notable dates in Jewish history is not a formidable task. I hope the Chronicle will broaden its search so that it will more effectively achieve what I assume is its intent to offer its readers glimpses into their rich history.

Ann Sheckter PowellPittsburgh

Still waving to cyclists, but gave up the HarleyIn regard to Life is a chai-way for these Jewish bikers (Aug. 7), I drove a Harley until I was 80 (I am now 95). I stopped because I couldnt lift it anymore. Also the helmet became too heavy. I wished there was a Jewish group then.I still have my jacket and trousers, if anyone wants them. They are fairly short.

Marion DamickSquirrel Hill

A small Jewish worldPittsburgh was my home for many years, but I now live in San Diego. Because of COVID-19, I havent met many people in my new retirement community. Our menu often has lox and bagels and pastrami sandwiches. Occasionally, even matzah ball soup. There are Shabbat services but theyve been cancelled because of quarantine rules. But I have been waiting to make my first Jewish friend. Guess who introduced us?

My daughter was visiting me outside and reading the Pittsburgh Jewish Chronicle to me. A gentleman strolled by on his walker and said, Oh, a Yiddishe maideleh is reading to her mameleh!

So the Chronicle introduced me to my first M.O.T. here in Paradise Village. Thought youd like to know.

Beverly King Pollockaka Quoth the Maven (Chronicle columnist 1967-78)San Diego, California

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Graham Carter: The challenge of facemasks when you have face blindness – Swindon Advertiser

Thursday, August 13th, 2020

Never before, in the field of human communication, was so much said by so many about so little.

It is only a piece of paper or cloth, for goodness sake, but the face mask debate rages on.

From the ceaseless parroting of the You must wear one orders on social media - yes, I know, I got the message when they said it was going to become law - to the rantings of those who are outraged at this supposed eroding of their liberties. Really?

Weve heard, ad nauseum, that they cause your glasses to steam up and make it difficult to read the facial expression underneath, and if you are as tired of the whole thing as I am, excuse me for introducing another thread into the debate, but it does seem to have been overlooked.

My big issue with face masks is trying to work out who is underneath.

For some years now, I have realised I suffer from prosopagnosia.

Proso-what?

You may well ask.

If I say it is also sometimes called face blindness you will probably get an idea that prosopagnosia is the inability to recognise people efficiently.

It is sometimes brought on by an accident or a stroke, but the majority of sufferers, including me, are born with it.

If you have it really bad, even recognising family members or yourself in the mirror can be a challenge, but for me it is relatively mild, and comes down to sometimes really struggling to recognise people.

You would be amazed, for instance, by my inability to name even some of the most famous faces in the world.

We are not talking about occasionally forgetting someones name, which happens to everybody, but always having to work hard to separate, put labels to, and then memorise or imagine different faces.

And if it was a struggle with a whole face, imagine the difficulty of seeing only half a face, thanks to a mask.

As with many minor mental disorders, our brains develop other strategies and skills to compensate, but there is the added complication for me in that I am also colourblind, so cant rely on identifying someones skin, hair or eye colour to help me identify them.

So face masks compound what is surely the ultimate social nightmare.

Few situations are more awkward than when somebody says hello to you in a supermarket and you cant work out who they are.

For all the disasters that 2020 has brought, however, at least this year is teaching us new lessons, and if you think about face blindness, there is another.

As many as two per cent of people suffer from it, yet the other 98 per cent are probably blissfully unaware that face recognition is an issue for some.

We should never forget that we all have our foibles, and every Tom, Dick and Harry has his own way of coping with what life throws at us.

Although dont ask me which is Tom, which is Dick and which is Harry.

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I am still here: Stephanie Gularte on her health, and the future of American Stage – St Pete Catalyst

Thursday, August 13th, 2020

Performing arts stages all across America, the Tampa Bay area included, first went dark on Friday, March 13. That was when the coronavirus curtain fell.

It was that same day Friday the 13th that American Stage producing artistic director Stephanie Gularte was diagnosed with a rare, degenerative disease that will eventually, inevitably erode her eyesight into next to nothing.

I got my genetic test results back the day we closed the theater, Gularte says. The universe has a sense of humor, for sure.

The disease retinitis pigmentosa was first detected when Gularte went to visit her optometrist for a new pair of reading glasses in February. She was sent to a retinal specialist the next day.

Shes unsure about the days, weeks and months ahead.

To be honest, Im still processing it, Gularte says. The biggest thing that I have come to learn is that theres a very significant range of impact before we think of blindness as being fully, one hundred percent blind.

Because retinitis pigmentosa is progressive, she expects a period of low vision to come first how long, doctors can only speculate. I realized that I need to make preparations to be able to be productive, with some limitations.

Its not uncommon, she has learned, for people to dismiss minor vision issues when something more serious lies just under the surface.

What I thought was clumsiness, and what I thought was kind of being distracted, bumping into things and knocking things over for the last few years, was actually the fact that my peripheral vision is compromised.

Night blindness, Ive struggled with since my 20s. And its kind of been a joke everybody whos worked with me in the theater knows that Stephanie needs help getting off the stage, if Im ever performing, or when the lights go down. I didnt realize that it was connected to something much more serious.

She has agreed to stay on with American Stage through early 2021.

Its not that I cant do my job, she explains. I intend to continue to be productive, and find a new way, creating a career that will allow me to continue to stay active as my vision declines. But what my position right now makes it difficult to do is prepare, and plan, and really assess how to be ready for change.

So it wasnt a matter of I cant do it any more, it came down to The best thing that I can do, the best gift I can give to myself right now, is stepping back and giving myself the time and opportunity to be very intentional about how I take care of myself, and how I plan for my future.

Her intention is to work with the company through its leadership transition, and ultimately to divide her time between St. Petersburg and her California hometown.

I want people to know that American Stage is going to be not just fine, but strong, Gularte says. Im not jumping on a jet plane to go take a job in another city. Im here. And so that transition is going to be managed very carefully, with great consideration for all of the other things the organization is dealing with.

I am still here and I still want to contribute to the community. And I dont know exactly what thats going to look like yet. Its not like this is it for me. Ive got a lot of energy still, and Ive got a lot I want to do.

I need to re-structure, and re-strategize, and my health will be the number one thing I make time and space for.

Gularte will address the situation on her Creative Collaborations podcast Monday, Aug. 24 at 6 p.m.

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I am still here: Stephanie Gularte on her health, and the future of American Stage - St Pete Catalyst

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‘Twister’ Was Filmed in a Small Oklahoma Town, Which Has a Museum Dedicated to the Film – Wide Open Country

Thursday, August 13th, 2020

The 1996 film Twister has stood the test of time. It has everything you'd need for a perfect action film -- Steven Spielberg as executive producer, Michael Crichton as screenwriter, and Jan De Bont ,who directed Speed, leading the charge onset (that's why the car scenes are so good). It's no wonder it was a biggest box office hit when it was released. (It was surpassed only by Independence Day.)

The film follows two storm chasers who are also an estranged couple on the verge of divorce, Bill and Jo, played by Bill Paxton and Helen Hunt. Inspired byThe Wizard of Oz, they created a machine they named "Dorothy," which they believe will help give people more time to prepare before severe storms hit. Accompanied by their misfit group of storm chaser friends and Bill's fiance Melissa (Jami Gertz), Bill and Jo set out to release their creation into the eye of the storm. There's some competition to get there first between the gang and Jonas, the cocky meteorologist (Cary Elwes) and nothing really goes as planned on their wild ride. The film delivers multiple incredible tornado scenes that still feel almost too real today.

Here are some things you probably didn't know about the beloved film.

Who could forget Hoffman's unique character, Dusty, who jammed out to music videos whenever they were driving into the action and regaled Melissa with stories of Bill's days as "The Extreme." He told Esquire that he took the role because he was trying to move across the country and needed the paycheck. Fair enough.

"I was living in L.A. at the time....and I knew if I took that job, I'd be able to move back to New York."

Paxton told Entertainment Weekly that in order to make the weather look accurate, there were a lot of lights on set that ended up giving him and Hunt temporary blindness. Luckily, there was no permanent damage after a few days. They wore special glasses and the crew put a filter over the lights.

"Those lights, they were like sun balls," says Paxton. "They had to pump light into the cab to get the exposure down, to make the sky behind us look dark, stormy. Because it was too bright outside. And these things literally sunburned our eyeballs. I got back to my room, I couldn't see."

Whedon, who is now known for Buffy the Vampire Slayer, Toy Storyand The Avengers, was brought on to help with rewrites. After getting bronchitis, the Oscar-winning screenwriter of Schindler's List, Steven Zaillian, was brought in. Whedon came back to help one more time before leaving again to get married.

According to Entertainment Weekly, De Bont threw a camera assistant into the mud at one point for ruining a take and even had up to 20 people just completely leave the set due to his intense attitude. But De Bont defended his actions, saying that it was a really difficult story to capture on film.

"With the wind machines it was very loud," says De Bont, "so the crew had to watch my hand signals. I cued action, and he [walked] right in the middle of the scene. We kept losing good performances because of stupid things like that. I don't think I'm a hothead, but I do believe you have to be passionate. These crews get paid well, and when they screw up, I'm going to call them on it."

Though there were certain scenes shot in Iowa, like the cornfield, the majority of filming took place around the state of Oklahoma. Apparently the original plan was to film in California but De Bont refused to film anywhere other than the heart of the real tornado alley.

The real-life small town was first scouted as a solid film location since it was not only tiny, but also had already endured some damage from a hailstorm a couple of years prior. Apparently, local residents were paid $100 a day to be extras in the film, and an older part of the town was even demolished during filming (on purpose, of course) to capture the aftermath of the tornado that ripped apart Aunt Meg's house.

Now the town has a museum dedicated to the film that's full of memorabilia including one of the Dorothy models. There's even a Twister-themed pinball machine that Paxton gifted to the museum. The film helped keep Wakita alive and even features a walking tour throughout to see all of the film locations. According to the museum's website, the town's residents loved Bill Paxton during filming as he was known to have a football on him at all times to play catch with the extras.

According to Variety, the film altered sounds from a camel's moan to create the sounds of the twister. That's one way to do it. Other reports have also claimed that a lion's roar was also added in to create the "roar" of the wind.

Luckily,producers worried that tagline would be taken too far by critics who didn't like the film, so this was changed to "the dark side of nature." Probably a good call.

Paxton told the AV Club that there had been talk of a sequel but nothing had happened. He even had a great idea for it because he felt the original was too "Pepsi Lite."

"There's a tougher version of that movie that I think now... I've kind of designed it so that me and Helen [Hunt] would have a daughter, a junior in high school, but she's already dating a guy in college, and we'd kind of hand it off to them. There's a great story of the Tri-State Tornado I'd like to tie into it as well."

Can you imagine watching country sensation Garth Brooks chasing around an f5 tornado instead of Bill Paxton? Well, according to a 2013 lawsuit,Brooks turned down the role because the twister was the real star of the film. The lawsuit was filed by Brooks' former employee Lisa Sanderson. Brooks has never publicly addressed the allegations. In 2014, Brooks won the lawsuit against Sanderson.

Michael Crichton and his wife, Anne-Marie Martin, were hired by Speilberg to write the script. You might remember another movie they worked on together...Jurassic Park. When an aspiring screenwriter sued Crichton and the studio saying that he had already pitched a script that was similar, Crichton claimed that the story was inspired by the film His Girl Friday as well as seeing real storm chasers on the TV.

Does anyone else find it weird that a film that came out in the mid-'90s has better special effects than movies coming out today? Just me? Well, apparently the Academy was so impressed that the film scored nominations for Best Sound as well as Best Visual Effects. You literally see a drive-in movie screen ripped apart so that seems pretty well deserved.

Is nothing sacred Hollywood?? According to Variety, Joseph Kosinski, director of the upcoming Top Gun: Maverick film is in discussions to direct. We can only hope that they do the beloved blockbuster justice as well as the late, great Bill Paxton.

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'Twister' Was Filmed in a Small Oklahoma Town, Which Has a Museum Dedicated to the Film - Wide Open Country

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Pandemic Conspiracies And Rumours Have Killed Over 800 People, Study Shows – ScienceAlert

Thursday, August 13th, 2020

Right now, a global infection is spreading from person to person, leading many to sickness and even death. We are not talking about the coronavirus. But it goes hand in hand with this other insidious plague.

The global spread in question is what researchers call an infodemic an oversupply of information, carrying with it fake news, rumours, and conspiracy theories that put people in harm's way. Bad ideas and poor advice, shared amongst friends, family, and total strangers alike.

In theory, an infodemic could attach to anything. This time, it's COVID-19. And it's a hugely serious problem that amplifies and extends the already grave dangers of the coronavirus crisis.

In a new study, an international team of infectious disease researchers scoured social media and news websites to monitor how COVID-19 misinformation was circulating on online platforms.

In total, they identified over 2,300 reports of COVID-19-related rumours, stigma, and conspiracy theories, communicated in 25 languages from 87 different countries.

None of this misinformation is helpful even if it's intended to be and much of it is harmful. In some cases, it's lethal, leading to preventable death and injury on a truly tragic scale.

"For example, a popular myth that consumption of highly concentrated alcohol could disinfect the body and kill the virus was circulating in different parts of the world," the authors write in their study.

"Following this misinformation, approximately 800 people have died, whereas 5,876 have been hospitalised and 60 have developed complete blindness after drinking methanol as a cure of coronavirus."

That incident, centred in Iran, might be the worst example of infodemic-related death, injury, and misery. But it's far from the only one the team found.

A similar event claiming the lives of 30 people was reported in Turkey, the researchers say, while in Qatar, two men died from ingesting either surface disinfectant or alcohol-based hand sanitiser.

In India, a dozen people became ill after drinking alcohol made from toxic datura seeds, having watched a video on social media that claimed it would boost their immunity against COVID-19. Five of the imbibers were children.

Of course, not every dangerous fallacy about coronavirus leads to hospitalisations that make headlines. Yet so many twisted ideas are out there and being shared, the researchers found, which people suggest can kill, cure, or prevent coronavirus things like drinking bleach, drinking cow urine and cow dung, ingesting silver solution, or spraying chlorine all over your body.

In the midst of this swirl of misinformation, even relatively benign mistruths can become dangerous in the wrong hands, the researchers say.

"A church in South Korea, where a spray bottle was used to spray salt water among the church attendees, resulted in more than 100 infections among the attendees because of spraying contaminated water," the team explains describing an incident in which the nozzle of a spray bottle was repeatedly put inside the mouths of different members of the congregation, without being disinfected.

The infodemic doesn't just perpetuate claims about false cures, though. It also has a lot to say about the origins of coronavirus, how you can catch it, and racial aspersions about who's to blame.

Some from the long list of examples includes: coronavirus is a type of rabies; mobile phones can transmit coronavirus; coronavirus is an engineered bio-weapon; coronavirus was made to sell vaccines; coronavirus was manufactured by the Bill & Melinda Gates Foundation/Donald Trump/the CIA/China (etc.); coronavirus is a population control scheme. And so on, and so on.

The researchers acknowledge a number of limitations to their study, and point out that they didn't investigate or follow up on the misinformation they discovered online, nor determine the number of people who believed in any given rumour or conspiracy.

Nonetheless, they did find all this misinformation freely circulating on publicly accessible websites and social media. That's the heart of the issue: the coronavirus infodemic is out there for all to see and it's a problem we need to actively counter, the researchers say.

"Misinformation fuelled by rumours, stigma, and conspiracy theories can have potentially serious implications on the individual and community if prioritised over evidence-based guidelines," the team writes.

"Health agencies must track misinformation associated with COVID-19 in real time, and engage local communities and government stakeholders to debunk misinformation."

The findings are reported in The American Journal of Tropical Medicine and Hygiene.

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Pandemic Conspiracies And Rumours Have Killed Over 800 People, Study Shows - ScienceAlert

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