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Archive for the ‘Biotechnology’ Category

Are Options Traders Betting on a Big Move in Puma Biotechnology (PBYI) Stock? July 03, 2017 – Zacks.com

Thursday, July 6th, 2017

Investors in Puma Biotechnology, Inc. (PBYI - Free Report) need to pay close attention to the stock based on moves in the options market lately. That is because the July 28th, 2017, $55 Puthad some of the highest implied volatility of all equity options today.

What is Implied Volatility?

Implied volatility shows how much movement the market is expecting in the future. Options with high levels of implied volatility suggest that investors in the underlying stocks are expecting a big move in one direction or the other. It could also mean there is an event coming up soon that may cause a big rally or a huge sell off. However, implied volatility is only one piece of the puzzle when putting together an options trading strategy.

What do the Analysts Think?

Clearly, options traders are pricing in a big move for Puma Biotechnology shares, but what is the fundamental picture for the company? Currently, Puma Biotechnology is a Zacks Rank #3 (Hold) in the Medical-Biomed/Genetics industry that ranks in the Bottom 37% of our Zacks Industry Rank. Over the last 60 days, 2 analysts have increased their earnings estimates for the current quarter, while none have dropped their estimates. The net effect has taken our Zacks Consensus Estimate for the current quarter from loss of $2.33 per shareto a loss of $2.13 in that period.

Given the way analysts feel about Puma Biotechnology right now, this huge implied volatility could mean theres a trade developing. Often times, options traders look for options with high levels of implied volatility to sell premium. This is a strategy many seasoned traders use because it captures decay. At expiration, the hope for these traders is that the underlying stock does not move as much as originally expected.

Looking to Trade Options?

Each week, our very own Dave Bartosiak gives his top options trades. Check out his recent live analysis and options trade for the TSLA earnings report completely free. See it here: Tesla Earnings Preview with Options Trade Ideas or check out the embedded video below for more details:

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Are Options Traders Betting on a Big Move in Puma Biotechnology (PBYI) Stock? July 03, 2017 - Zacks.com

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Noxxon/MSD start testing of immunoncologic combo – European Biotechnology

Tuesday, July 4th, 2017

Last December, Noxxon Pharma AG signed an agreement with Merck & Co./MSD to evaluate the synergistic potential of NOXA1/2 and pembrolizumab immune cancer therapy. Now, the companies have kicked off a Phase I/II study in patients with pancreatic and colorectal cancer.

The study conducted at the National Center for Tumor Diseases in Heidelberg (Germany) will investigate the impact of NOX-A12 (olaptesed pegol) as a monotherapy on immune cell infiltration into tumors. In addition, Noxxon and Merck & Co will assess safety and efficacy of NOX-A12 in combination with Keytruda (pembrolizumab), Merck & Co./MSDs programmed death receptor-1 (PD-1) immune checkpoint-blocking antibody drug.

The open-label trial (NCT03168139) is composed of two parts: patients will receive NOX-A12 monotherapy for two weeks, followed by combination therapy of NOX-A12 plus pembrolizumab for up to two years. 20 patients will be enroled: 10 patients for each metastatic pancreas and colorectal cancer.

The design of the clinical trial was a collaborative effort between NOXXON and MSD. Part 1 of the study, in which patients will receive NOX-A12 monotherapy for up to two weeks, will evaluate immune infiltrate changes within the tumor microenvironment induced by CXCL12 inhibition with NOX-A12 by comparing pre- and post-treatment biopsy specimens as well as the safety and tolerability of NOX-A12 in patients with metastatic (stage IV) colorectal and pancreatic cancer. Part 2 of the study, in which NOX-A12 is to be combined with Keytruda, will assess the safety and tolerability of the combination in addition to the efficacy of treatment. Top-line data for all 20 patients from part 1 is expected to be available in Q2/2018, and initial response-rate data in Q4/2018.

NOX-A12 inhibits CXCL12, a key tumor microenvironment chemokine and a stem cell migration factor. The chemokine that acts by binding to to CXCR4 and CXCR7 may be a key partner for a wide range of IO (immuno-oncology) agents. Noxxon has generated promising pre-clinical and clinical data, including animal data showing synergy with a checkpoint inhibitor, as well as recent phase 2a trials in multiple myeloma and a second hematological cancer that showed a safety profile that supports further development and first signs of efficacy. The company said that its study will position the drug to be combined with multiple classes of IO approaches including those acting on or through T cells and/or NK cells.

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Noxxon/MSD start testing of immunoncologic combo - European Biotechnology

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iShares Nasdaq Biotechnology Index Fund (IBB) Earns Slightly Optimistic Media Opinion, Based On A Study – Insider Tradings

Tuesday, July 4th, 2017

News stories about iShares Nasdaq Biotechnology Index Fund (NASDAQ:IBB) have been gaining in popularity quite recently, Accern reports. The analysis company ranks negative and positive press coverage by studying larger than 20 Million SEC financial documents and social media sites sources in real-time. Accern grades analysis of companies ranging from -1 to 1, with ranks nearest to 1 is considered more positive. iShares Nasdaq Biotechnology Index Fund achieved a news impact rank of 0.10 on Accerns range. Accern also gave media analysis about the financial services provider a media impact point of 0 out of 100, indicating that recent press coverage is very unlikely to have an effect on the firms share value next many days.

Stocks of iShares Nasdaq Biotechnology Index Fund (NASDAQ:IBB) started trading at 310.95 on early Tue. the company has 50 Day SMA price of $297.52 and a two hundred SMA of $288.98. iShares Nasdaq Biotechnology Index Fund has a 1 year low of $246.71 and a 1 year high of $323.45.

Few press stories that May have effected Accern trend Analysiss analysis:

Also, the company disclosed a divided for the quarter, to be paid on early Fri, Jun 30th. Traders who own the stock with a record date on Thurs, Jun 29th were given a dividend of $0.1768 for a share. this indicates a $0.71 dividend on a yearly basis and a payout of 0.23%. The ex-dividend date was Tue, Jun 27th.

IBB has been the discussion subject of Quite a few brokerage firm research. Credit Suisse Group boosted iShares Nasdaq Biotechnology Index Fund from a market weight recommendation to an overweight recommendation in a analysis note on Tue, Mar 21st. The move was based on the current stock valulation. crowd sourced stock rating company Vetr boosted iShares Nasdaq Biotechnology Index Fund from a hold recommendation to a buy recommendation and fixed a $300.66 PT on the shares in a study note on early Tue, Apr 18th.

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iShares Nasdaq Biotechnology Index Fund (IBB) Earns Slightly Optimistic Media Opinion, Based On A Study - Insider Tradings

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Puma Stalks Up – Puma Biotechnology, Inc. (NYSE:PBYI) | Seeking … – Seeking Alpha

Tuesday, July 4th, 2017

Puma Biotechnology, (NYSE:PBYI) is a $3.2 billion market cap company initially focused on developing tyrosine kinase inhibitor neratinib (PB272) for HER2 positive breast cancer. The company has conducted 11 clinical trials for its lead candidate, with over 2,000 patients contributing to a favorable risk-benefit profile, per inflection point clinical trial readouts over the past quarter. Oncologic Drugs Advisory Committee (ODAC) at FDA recently voted for approval of neratinib in HER2 positive extended adjuvant treatment of early stage breast cancer in May 2017. ODAC vote is not binding but carries strong weight in the decision-making process. Given FDA director Gottlieb's new aggressive policies regarding the slow and outdated drug approval process at FDA, this was seen by the market as a "sure thing". The company is advancing neratinib in discussions with EMA for European markets, with validation in August 2016. Other investigations include neratinib in combinatory therapy for metastatic breast cancer and in solid tumors as well.

Neratinib blocks signal cascades of epidermal growth factor receptors or EGFRs, specifically: HER1, HER2, HER3, and HER4. A number of studies are showing nice anti-tumor efficacy. Taken together with ODAC favor, Phase 3 result emphasis for neratinib which met primary endpoints appears to have led to the robust response in the market for high probability of FDA approval. Two-year disease-free survival showed a 2.4% improvement for neratinib versus placebo in ITT population. Five-year disease-free survival showed a 2.5% improvement. In HR+ patients, neratinib adjuvant therapy showed a two-year disease-free survival rate of 95.4% compared to 91.2% in placebo. Five-year disease-free survival conferred a 4.8% benefit. Two-year HR patients' disease-free survival showed a meaningful advantage, but five-year data was not statistically significant.

The company recently presented data June 3 at ASCO 2017 summarizing positive results of its Phase 2 trial in HER2-positive metastatic breast cancer that has metastasized to the brain. Nearly half of the patients in a neratinib plus chemotherapy cohort achieved a central nervous system (CNS) objective response with overall survival data remaining immature at 13.5 months (and counting). CNS progressions remain a huge comorbidity factor in patients with brain metastases. With the ability to cross the blood-brain barrier, and with diarrhea being the number one adverse event, PBYI is well-positioned to advance in this space with neratinib. Studies examining antidiarrheal prophylaxis (Loperamide) to reduce diarrhea severity during neratinib treatment have proven effective. Phase 3 data showed grade 3 diarrhea decreased from ~40% to ~31% with loperamide, to ~23% with loperamide and budesonide, and to 11.5% with loperamide and colestipol. Safety studies examining children and young adults with cancer are also ongoing.

Multiple studies are generating impressive cancer therapy data for neratinib, including clinical data presented at AACR on neratinib in the treatment of patients who have solid tumors with activating HER2 or HER3 mutations. Additional data was also presented on the combination of T-DM1 and neratinib in patients with HER2 positive metastatic breast cancer (MBC) that has previously been treated with pertuzumab and trastuzumab. The company has done extensive analysis of breast cancer NSABP FB-7 biomarker during neratinib treatment with a variety of immuno and chemotherapy regimens to qualify its objective tumor response. Mechanistically, phosphoHER2 levels and truncated HER2 mutants (p95HER2) demonstrated statistically significant higher levels in patients who achieved a pCR with neratinib than those treated with trastuzumab or trastuzumab plus neratinib who did not. Moreover, dual pathway suppression (HR/ER+ and EGFR/HER2+) has been seen only in neratinib and not in Herceptin and Tykerb (Novartis (NYSE:NVS)).

The company has listed other potential tissue types to expand its label for neratinib, including non-small cell lung cancer, colorectal cancer, and solid tumors (any HER2-associated tumors). Roche (OTCQX:RHHBY) annual sales for Herceptin (trastuzumab) approach $5 billion. In contrast, Tykerb has not fared as well due to its unfavorable toxicity profile, with sales in the hundreds of millions. The HER2 positive breast cancer market is estimated to be about $13 billion by 2023. Given this massive market and plenty of room to expand label into other high dollar indications, Puma may still have quite a bit of upside and is generally de-risked. It certainly becomes very attractive on any stock price pullbacks.

Puma reported at end of 1Q 2017 cash and cash equivalents of $105.1 million and marketable securities of $88.9 million, with a 1Q net loss of $72 million. Cash runway is expected to last through mid-2018, with a burn rate of approximately $35 million per quarter. If the company is forced to raise funds, it should be able to do so at a good market value, given the advanced stage of its drug development. Strong Bio recommends a watch list spot for the stock and manageable delays or setbacks as a potential buying opportunity. Moreover, it may be a takeover candidate and could undergo some downward volatility in the standard process of stop-loss triggering. Such swoons will probably not last long as market support should be strong. With market cap of $3 billion and potential market quite a bit larger, there is plenty of room for value position here if sales meet expectations.

Risks for the company to investors are primarily centered around its one-trick pony pipeline. But when the trick is good enough, it's going to bring bank. Its advantage in efficacy will certainly gain a reasonable stake in the market for those that can tolerate the adverse events. In fact, the adverse event of diarrhea is somewhat severe, but luckily, most of that risk was mediated with appropriate prophylaxis regimen. It perhaps would have contraindications for those with extreme inflammatory bowel or related disorders. FDA-related large scale manufacturing risks and regulatory hurdles could prove to add delays and pitfalls to Puma's terrain, and since this is the only revenue-maker in its pipeline, a lot hinges on its expeditious advancement. However, given the aggressive stance at FDA to get life-saving therapies available to patients, most regulatory risks are ameliorated. Partnership decisions will be important inflection points moving forward.

Disclosure: I/we have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours.

I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Editor's Note: This article discusses one or more securities that do not trade on a major U.S. exchange. Please be aware of the risks associated with these stocks.

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Puma Stalks Up - Puma Biotechnology, Inc. (NYSE:PBYI) | Seeking ... - Seeking Alpha

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Researchers in Melbourne provide new biotechnology tool – BSA bureau (press release)

Tuesday, July 4th, 2017

A team of researchers at the University of Melbourne has used a quantum probe to perform microwave-free NMR at the nanoscale.

Researchers at the University of Melbourne have demonstrated a way to detect nuclear spins in molecules non-invasively, providing a new tool for biotechnology and materials science.

Important research in medicine and biology relies on nuclear magnetic resonance (NMR) spectroscopy, but until now, it has been limited in spatial resolution and typically requires powerful microwave fields. A team of researchers at the University of Melbourne has used a quantum probe to perform microwave-free NMR at the nanoscale.

This quantum probe delivers a dramatic improvement in NMR technology. In addition to being able to detect NMR in far smaller samples than conventional machines, the technique does not require the application of microwave fields that might disrupt biological samples.

The discovery may overcome significant limitations with conventional NMR methods, which depend on machines that can exceed 10 tonnes.

With these advances in quantum sensing technology, doors can open to a new world of scientific investigation that could lead us to gain a better understanding of the smallest building blocks of life.

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Researchers in Melbourne provide new biotechnology tool - BSA bureau (press release)

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Prana Biotechnology shares surge after journal publication – Proactive Investors UK

Tuesday, July 4th, 2017

Shares in Prana Biotechnology (NADSAQ:PRAN) surged 19% and was earlier higher in New York as it said an article about early data on PBT434 had been accepted in a peer review journal.

The article deals with the fact the compound PBT434 prevents iron-mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinsons disease.

Dr David Stamler, Pranas chief medical officer, said: These findings are important because Parkinsons disease and the related synucleinopathies cause significant disability and diminish the independence of afflicted individuals.

"An agent which slows disease progression could have a great impact on reducing disease burden and improving quality of life. We are eager to begin clinical testing of PBT434.

The publication is the culmination of ten years of research from scientists at the Florey Institute of Neuroscience and Mental Health, (Melbourne, Australia), investigating compounds from Prana Biotechnologys propriety chemical library.

Not only was PBT434 shown to block alpha-synuclein accumulation, but it also prevented loss of nerve cells in the region of the brain primarily affected in Parkinsons disease.

To investigate the therapeutic potential of PBT434 to slow neurodegeneration, the researchers performed extensive animal testing in multiple Parkinsons disease models, including tests in mice that over-expressed the alpha-synuclein protein.

These results showed that PBT434 lowered alpha-synuclein and its toxic effects and simultaneously improved motor performance.

Shares added 19% to $2.73.

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Prana Biotechnology shares surge after journal publication - Proactive Investors UK

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Biotechnology Separation Systems Market 2017 Industry Analysis … – World Of WallStreet

Saturday, July 1st, 2017

Biotechnology Separation Systems Market

Overview

The report on the Global Biotechnology Separation Systems Market 2017 gives complete view of the market across the globe. In-depth analysis comprising key market players, market forecasts, supply, demand, profit, latest market trends, and many more are provided in the report below. The future aspects impacting the global market in every possible way are also further discussed in the report.

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Biotechnology Separation Systems Market: Research methodology

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Additional information provided in the report

In addition, considering that the global economy is ever-changing depending upon several factors , it is important to take a note that our report contains data that are not only conducted regarding CAGR forecasts but it also analyzes the key parameters such as yearly market growth in order to have complete information about the future of the market worldwide. It also helps in identifying the wide opportunities that will open up for the market. The other key feature included in this report is the analysis of the revenue forecasts of all the important regions and applications, which is in terms of dollars.

About Market research Store

Market Research Store is a single destination for all the industry, company and country reports. We feature large repository of latest industry reports, leading and niche company profiles, and market statistics released by reputed private publishers and public organizations. Market Research Store is the comprehensive collection of market intelligence products and services available on air. We have market research reports from number of leading publishers and update our collection daily to provide our clients with the instant online access to our database. With access to this database, our clients will be able to benefit from expert insights on global industries, products, and market trends.

Contact Us:

Joel John 3422 SW 15 Street, Suit #8138, Deerfield Beach, Florida 33442, USA USA Tel: +1-386-310-3803 GMT Tel: +49-322 210 92714 USA/Canada Toll Free No.1-855-465-4651 Email: sales@marketresearchstore.com Web: http://www.marketresearchstore.com/

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Biotechnology Separation Systems Market 2017 Industry Analysis ... - World Of WallStreet

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Nerium Biotechnology Shareholders Overwhelmingly Elect All Six Management Nominees to Nerium’s Board – Marketwired (press release)

Saturday, July 1st, 2017

SAN ANTONIO, TEXAS--(Marketwired - June 30, 2017) - Nerium Biotechnology, Inc. ("Nerium" or the "Company") is pleased to announce the voting results of its annual meeting of shareholders (the "Meeting") held on June 29, 2017 in Toronto, Ontario, Canada. This year's Meeting had extraordinary participation from Nerium's shareholders, with a total of 31,272,131 common shares, or approximately 85.75% of the outstanding common shares of Nerium, having been voted at the Meeting.

We are pleased to announce that Nerium's shareholders voted to elect all six of Nerium's director nominees to the board of directors (the "Board"). Each Nerium director nominee received at least 77% of the votes cast by shareholders present in person or represented by proxy at the Meeting. The dissident's director nominees each received 20% of the votes cast by shareholders, which includes the 7.48% of the votes cast by the dissident shareholders. The voting results of the election of directors are as follows:

"We thank Nerium's shareholders for their consideration and support during this process," said Richard Boxer, Chair of the Special Committee of Nerium's Board. "We are pleased that the Company's shareholders voted overwhelmingly to reject the dissident's nominees and elect all of Nerium's nominees to the Board. Your directors will continue to act in the best interests of Nerium and all of its shareholders, and are committed to addressing legitimate shareholder concerns. We intend to provide shareholders with a more detailed update on the Company's business in the coming weeks."

All other matters set out in the Company's management information circular were approved by the requisite majority of the shareholders at the Meeting.

About Nerium Biotechnology, Inc.

Nerium Biotechnology, Inc. is a biotechnology company involved in the research, product development, manufacture and marketing of Nerium oleander-based products. The Company's shares are not listed on any stock exchange or quotation system.

Forward Looking Statements: Statements made in this press release that relate to future plans, expectations, events or performances are forward looking statements. Forward-looking statements are not based on historic facts, but rather on current expectations regarding future events. They are based on information available to management and/or assumptions management believes are reasonable. Many factors could cause future events and outcomes to differ materially from those discussed in the forward-looking statements. Although the forward-looking statements are based on what management believes are reasonable assumptions, the Company cannot assure shareholders that actual results will be consistent with these forward-looking statements. The forward-looking statements in this press release are made as of the date hereof and, except as required by applicable securities laws, the Company does not assume any obligation to update or revise such forward-looking statements. More information about the Company is available in its disclosure documents, all of which are available on the Company's issuer profile on SEDAR at http://www.sedar.com.

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Nerium Biotechnology Shareholders Overwhelmingly Elect All Six Management Nominees to Nerium's Board - Marketwired (press release)

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Biotechnology crops dominate Nebraska crop fields – Grand Island Independent

Saturday, July 1st, 2017

Biotechnology varieties of corn and soybeans make up 95 percent of the 15.5 million acres planted this spring by Nebraska farmers, according to a report from the USDAs National Agricultural Statistics Service on Friday.

According to the report, Nebraska corn growers planted 9.8 million acres, down 1 percent from last year. Biotechnology varieties were used on 96 percent of the area planted, up 1 percentage point from a year ago. Growers expect to harvest 9.5 million acres for grain, which is down 1 percent from last year.

Statewide, soybean planted area is estimated at 5.7 million acres, up 10 percent from last years total and a record high. Of the acres planted, 94 percent were planted with genetically modified, herbicide resistant seed, down 2 percentage points from a year ago. Acres expected to be harvested are 5.65 million, up 10 percent from a year earlier.

Last year, Nebraska ranked sixth in the nation in harvested acres of principal crops at 19,223,000 acres.

Nationwide, the USDA reported that corn planted area for all purposes in 2017 is estimated at 90.9 million acres, down 3 percent from last year. Compared with last year, planted acres are down or unchanged in 38 of the 48 estimating states. Area harvested for grain, at 83.5 million acres, is down 4 percent from last year.

Soybean planted area for 2017, nationwide, is estimated at a record high 89.5 million acres, up 7 percent from last year. Compared with last year, planted acreage intentions are up or unchanged in 24 of the 31 estimating states.

The USDA reported that winter wheat seeded in the fall of 2016 totaled 1.11 million acres, down 19 percent from last year and a record low. Harvested acreage is forecast at 1 million acres, down 24 percent from a year ago.

Along with declining wheat acres, Nebraska wheat farmers are also having to deal with a wheat virus outbreak that has reached epidemic levels and has been damaging fields and yields in the southern Nebraska Panhandle, according to the Associated Press. The Nebraska Wheat Association earlier this month reported that as many as 85 percent of southern Panhandle fields have been affected by the virus.

Nationwide, all wheat planted area for 2017 is estimated at 45.7 million acres, down 9 percent from 2016. This represents the lowest all wheat planted area on record since records began in 1919. The 2017 winter wheat planted area, at 32.8 million acres, is down 9 percent from last year. Of this total, about 23.8 million acres are hard red winter.

For other Nebraska crops, the USDA reported that:

Alfalfa hay acreage to be cut for dry hay is at 770 thousand acres, up 3 percent from 2016. Other hay acreage to be cut for dry hay is 1.70 million acres, unchanged from last year.

Sorghum acreage planted and to be planted, at 140 thousand acres, is down 30 percent from a year ago. The area to be harvested for grain, at 110 thousand acres, is down 37 percent from last year.

Oats planted area is estimated at 115 thousand acres, down 15 percent from the previous year. Area to be harvested for grain, at 25 thousand acres, is unchanged from a year ago.

Dry edible bean planted acreage is estimated at 150 thousand acres, up 9 percent from last year. Harvested acres are estimated at 139 thousand acres, up 14 percent from the previous year.

Proso millet plantings of 130 thousand acres are up 37 percent from a year ago.

Sugarbeet planted acres, at 49.7 thousand, are up 4 percent from last year.

Oil sunflower acres planted are estimated at 55 thousand, up 90 percent from last year. Non-oil sunflower planted acreage is estimated at 6 thousand acres, down 52 percent from a year ago and a record low.

Dry edible pea estimated planted acres are 45 thousand acres, down 18 percent from last year. Harvested acres are estimated at 42 thousand, down 19 percent from the previous year.

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Biotechnology crops dominate Nebraska crop fields - Grand Island Independent

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Director General of Nigeria’s biotechnology agency arrested over … – Premium Times

Friday, June 30th, 2017

The Economic and Financial Crimes Commission, EFCC, says it has arrested Lucy Ogbadu, the Director-General of National Biotechnology Development Agency (NABDA), over alleged N23 million fraud.

The spokesperson of the commission, Wilson Uwujaren, disclosed this in a statement he issued on Thursday.

Mr. Uwujaren said Ms. Ogbadu was picked up by EFCC operatives in Port Harcourt on Wednesday, following her alleged link with the Bayelsa State Director of Bio-resources Development Centre, Josiah Habu.

Mr. Habu, according to him, is being investigated by the anti-graft agency in a case of fraudulent diversion of N75 million.

He said investigations by the EFCC revealed that Ms. Ogbadu allegedly received N23 million through a bank account belonging to the wife of Mr. Habu, Esther Habu.

The EFCC spokesperson stated that Ms. Ogbadu admitted the transaction in a voluntary statement made to the commissions investigators.

Further investigations also revealed that Mrs Habu is one of the contractors with Bio-resources Development Centre, Odi, Bayelsa State.

A total of N603 million has been traced to her in different deals involving over 20 directors of the centre across the country.

Ogbadus involvement is being investigated. She has been duly served with bail conditions while investigations continue, Mr. Uwujaren added.

Ms. Ogbadu, a professor of microbiology, was appointed NABDA director-general in November 2013.

(NAN)

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Director General of Nigeria's biotechnology agency arrested over ... - Premium Times

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AML: Cellectis testing allogenic CAR-T cell therapy – European Biotechnology

Thursday, June 29th, 2017

Genome editing specialist Cellectis has kicked off clinical tests in the US for the very first of-the-shelf CAR-T cell therapy in acute myeloid leukaemia.

The company said it enrolled the first patient with acute myeloid leukaemia (AML) to be treated with UCART123 at Weill at Cornell Medicine, New York Presbyterian Hospital. UCART123 is a TALEN-genome edited chimeric T cell receptor targeting the CD123/IL3R antigen on the surface of blasts and dendric cells, which is administered on allogeneic donor T cells. The team of Gail J. Roboz will investigate the safety and will collect first indications for efficacy of UCART123 in patients with AML. The Phase I trial is part of a strategic translational research alliance that was formed between Cellectis and Weill Cornell Medicine in 2015.

While Novartis AG and Kite Pharma are leading the CAR-T cell therapy development in AML, Cellectis hopes to overtake its competitors. It has the only approach that works with allogenic CAR-engineered T cells that could be centrally pre-manufactured in contrast to the autologous patient T cells. Those need to be isolated, engineered and expanded during the at least 14 day hospital stay of the patients to be treated making the procedure costly, lengthy and laborious. On the other hand, Cellectis therapy does not target the CD19 T cell antigen but CD123//IL3R giving the company another unique selling point.

Cellectis has used TALEN technology to block expression of the TCRa constant (TRAC) gene though blocking expression of the natural TCR. According to Andr Choulika, Cellectis CEO, TALEN technology shows less off-target effects compared to CRISPR/Cas9 genome editing. Following apheresis, donor T cells are engineered to express an anti-CD123 CAR (CD123 scFv-41BB-CD3z) and an RQR8 depletion ligand that confers susceptibility to rituximab. Theoretically, specifity of of UCART123 therapy might be higher in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) than in patients with AML as CD123 expression is 10fold higher in the precursors of plasmacytoid dendritic cells than in blast occurring in the course of AML.

Cellectis also announced two new entries to ists Board of Directors. Ex-Novartis pharma division head Rainer Boehm will lead commercialisation of Cellectis lead candidate. Ex Novartis Oncology President and Incyte Corp CEO Herv Hoppenot will lead clinical development.

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AML: Cellectis testing allogenic CAR-T cell therapy - European Biotechnology

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Explore Innovations in Industrial Biotechnology at Upcoming … – Newswise (press release)

Thursday, June 29th, 2017

Newswise Industrial biotechnology scientists, educators, entrepreneurs and executives from around the globe will be convening on the University of California San Diego campus this summer to explore the latest advances and world-changing innovations heating up the white-hot field of industrial biotechnology with workshops in microbial fermentation and metabolic engineering.

UC San Diego Extension will host its annual Industrial Biotechnology Workshops on Aug. 14 through 18. Participants can attend the whole program or attend the workshops on microbial fermentation or metabolic engineering separately.

Now in its fifth year, this widely acclaimed educational event creates an informal, intimate environment for robust exchange of knowledge and ideas among world-class academic instructors and leaders of cutting-edge companies of every size from startup to mature, said Hugo Villar, associate dean of Professional & Continuing Education for UC San Diego Extension.

Whether from California or China, biotechnology professionals attending these workshops will have a front-row seat to learn about current developments and advanced scientific skills being used to solve some the worlds most difficult problems, Villar said.

Microbial Fermentation

For the past four years, the workshop focused primarily on microbial fermentation, which is the transformation of feedstocks, such as plant sugars, into useful products, like fuels, chemicals, beer or antibiotics, by bacteria, yeast, fungi or algae.

The Microbial Fermentation Workshop will be held Aug. 16 to 18. Participants will be introduced to the fundamental knowledge and practical skills needed to design, develop, optimize, control, scale-up, analyze and troubleshoot fermentation processes.

As one of just a handful of programs in the world that provide in-depth, practically oriented coursework in microbial fermentation, it is expected to draw participants from Connecticut to Croatia.

While workshop participants should have some basic knowledge and experience in fermentation, everyone from scientists to biotech business executives to graduate students could benefit from the microbial fermentation workshop.

This years program features some of the brightest minds in the field, including:

Jeff Lievense, senior advisor of Bioengineering & Technology, Genomatica;

Rachel Dutton, assistant professor of Molecular Biology, UC San Diego;

Michael Japs, senior director of Process Technology, Genomatica;

Jon Hansen, principal of New Leaf Biotech;

Jason Ryder, vice president, Process R&D, Hampton Creek; and

Karen Fortmann, senior research scientist, White Labs.

Five interactive case studies, including production of microbes for cheese and beer, will allow attendees to practice what they learn, while the Fermentation Firing Line segment will offer a lively, open ended forum for posing questions to the instructional team on fermentation-related topics.

In addition, everyone in attendance can participate in a tour of the global headquarters of White Labs, which produces yeast for beer making, and attend a hosted reception in its craft beer tasting room.

Metabolic Engineering

A new segment on metabolic engineering, which will run Aug. 14-15, will also be offered.

Recently named as one of the top 10 emerging technologies by the World Economic Forum, metabolic engineering focuses on the design and development of equipment and processes for manufacturing products such as agriculture, food, animal feed and pharmaceuticals.

Instructors joining the interactive course with case studies throughout the curriculum include:

John Pierce, MIT lecturer and former scientist at multinational firms BP and DuPont;

Adam Feist, project scientist, UC San Diego;

Ben Griffin, senior director, Microbial and Enzyme Engineering, Synthetic Genomics;

Jeff Lievense, senior advisor, Genomatica;

Jim Mills, chief technology officer, BioAmber, Inc.;

Bernhard Palsson, principal investigator, UC San Diego; and

Kristy Salmon, head of research, BP.

Those who attend the Metabolic Engineering segment are also invited to participate in a tour of the global headquarters of White Labs, which produces yeast for beer making, and attend a hosted reception in its craft beer tasting room.

Those interested in finding out more about the upcoming workshops can visit http://extension.ucsd.edu/industrialbiotech , call (858) 534-9353 or email unexbio@ucsd.edu.

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Explore Innovations in Industrial Biotechnology at Upcoming ... - Newswise (press release)

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Puma Biotechnology (PBYI) Earns Slightly Unfavorable Press Analysis, Based On In-Depth Analysis – Insider Tradings

Thursday, June 29th, 2017

Press articles about Puma Biotechnology (NYSE:PBYI) has been popular fairly negative last few days, Accern reports. The analytics team pointing out the bullish and bearish news analysis by observing larger than 20 Million public financial documents, market websites and SEC sources in real-time. Accern grades analysis of public companies ranging from -1 to 1, with ranks nearest to 1 is considered more positive. Puma Biotechnology achieved a news impact rank of -0.01 on Accerns range. Accern issued stories about the biopharmaceutical company a media impact point of 66 out of 100, pointing that recent news analysis is likely to impact the share value upcoming future.

Puma Biotechnology (NYSE:PBYI) previously disclosed its earnings report on early Wed, May 10th. The biopharmaceutical business posted ($1.97) Earnings per share for the period, reaching the Thomson Reuters average forecast of ($2.06) by $0.09. Brokerage firms predict that Puma Biotechnology to post ($8.50) earnings per share for the full year.

Puma Biotechnology (NYSE:PBYI) transacted up 4.71% throughout intraday market trading on early Wed, topping $88.85. the share had a trading volume of 872,030 Stocks. Puma Biotechnology has a 52 week low of $27.64 and a 52 week high of $92.00. The stocks market valuation is $3.28 B. Companys 50 Day SMA is $59.74 and its 200 day SMA is $42.39.

PBYI has been the topic of many Study analysis. Citigroup boosted Puma Biotechnology to a buy recommendation and fixed a $105.00 target price for The corporation in a study note on Sunday, May 28th. Zacks Lowered Puma Biotechnology from a buy recommendation to a hold recommendation in a analysis note on early Wed, Jun 14th. Stifel Nicolaus reiterated a buy recommendation and fixed a $105.00 target price on stock of Puma Biotechnology in a study note on early Mon, Jun 5th. J P Morgan Chase & Co reissued an overweight recommendation and fixed a $89.00 target price on stock of Puma Biotechnology in a study note on early Tue, Jun 6th. Lastly, Royal Bank Of Canada boosted their target price on Puma Biotechnology from $60.00 to $88.00 and issued the shares a sector perform recommendation in a analysis note on Tue, Jun 6th. 1 investment expert has recommended the share with a sell recommendation, two have published a hold recommendation and six have published a buy recommendation to The corporation. Puma Biotechnology currently has a average recommendation of Buy and an consensus price target of $86.94.

In other Puma Biotechnology news, large stockholder Adage Capital Partners Gp, L.L unloaded 507,128 stocks of the firms shares in a trade on early Mon, Jun 5th. The stock was unloaded at a price range of of $87.84, amounting $44,546,123.52. The information was declared in a transaction filed with the securities and exchange commission, which is available through the Security and Exchange Commission website. executive have unloaded 1,990,088 stocks of company shares valued $157,553,113 during the last ninety days. Executives own 22.70% of the firms stock.

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Puma Biotechnology (PBYI) Earns Slightly Unfavorable Press Analysis, Based On In-Depth Analysis - Insider Tradings

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ChineseInvestors.com, Inc.’s Wholly-owned Foreign Enterprise, CBD Biotechnology Co. Ltd., Will Launch its First Hemp … – PR Newswire (press release)

Wednesday, June 28th, 2017

The new skin care line is expected to be launched in the third calendar quarter of 2017. CBD Biotechnology Co. Ltd. plans to use multiple sales channels to implement its sales plan including Tmall, TaoBao, the Company's official website, broadcasting platforms of internet celebrities, mobile news applications, and a multi-level direct selling system in cooperation with Shangdong Yibao Biologics Co. Ltd.

"Following the launch of OptHemp Ultra Premium Hemp Oil by CIIX's wholly owned U.S. subsidiary, ChineseHempOil.com, Inc., I am very pleased to announce the launch of CBD Biotechnology Co., Ltd. non-industrial hemp infused skin care line," says Summer Yun, CEO of CBD Biotechnology Co., Ltd. "CBD Biotechnology Co., Ltd. will be one of the first companies in China to incorporate hemp-based CBD into skin care products, which we believe will spark public interest.

"An estimated 55,700 metric tons of industrial hemp are produced around the world each year with China, Russia, and South Korea leading in production, accounting for 70 percent of the world's industrial hemp supply. Although China is one of the leading producers of industrial hemp, the benefits to the human body have not yet been widely recognized in mainland China," says Yun. "As one of the companies company to introduce a skin care line infused with hemp-based CBD to China, CIIX looks forward to educating the almost 1.4 billion people in China about the benefits of hemp-based CBD and the positive effects it can have on the largest, visible human organ - the skin!"

About ChineseInvestors.com (OTCQB: CIIX)

Founded in 1999, ChineseInvestors.com endeavors to be an innovative company providing: (a) real-time market commentary, analysis, and educational related services in Chinese language character sets (traditional and simplified); (b) advertising and public relation related support services; and (c) retail, online sales and direct sales of hemp-based products and other health related products.

For more information visit ChineseInvestors.com

Subscribe and watch our video commentaries: https://www.youtube.com/user/Chinesefncom

Follow us on Twitter for real-time Company updates: https://twitter.com/ChineseFNEnglsh

Like us on Facebook to receive live feeds:https://www.facebook.com/Chinesefncom

Add us on WeChat: Chinesefn or download iPhone iOS App: Chinesefn.

Forward-Looking Statements

This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended and Section 21E of the Securities Exchange Act of 1934, as amended. All forward-looking statements are inherently uncertain as they are based on current expectations and assumptions concerning future events or future performance of the company. Readers are cautioned not to place undue reliance on these forward-looking statements, which are only predictions and speak only as of the date hereof. In evaluating such statements, prospective investors should review carefully various risks and uncertainties identified in this release and matters set in the company's SEC filings. These risks and uncertainties could cause the company's actual results to differ materially from those indicated in the forward-looking statements.

Contact: ChineseInvestors.com, Inc. 227 W. Valley Blvd, #208 A San Gabriel, CA 91776

Investor Relations: Alan Klitenic +1-214-636-2548

Corporate Communications: NetworkNewsWire (NNW) New York, New York http://www.NetworkNewsWire.com +1-212-418-1217 Office Editor@NetworkNewsWire.com

SOURCE ChineseInvestors.com, Inc.

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ChineseInvestors.com, Inc.'s Wholly-owned Foreign Enterprise, CBD Biotechnology Co. Ltd., Will Launch its First Hemp ... - PR Newswire (press release)

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Karnataka IT and Biotechnology Dept Grants Rs 3.18 cr to 12 Start-ups – News18

Wednesday, June 28th, 2017

Bengaluru: The Karnataka IT and Biotechnology department on Wednesday granted Rs 3.18 crore to fund 12 start-ups in the areas of agriculture, biotechnology, security, communications and robotics.

"The dozen start-ups have been selected for funding to innovate products and solutions as they have been part of the Idea2PoC (Proof of Concept) scheme of the IT department's Start-up Cell," said an official statement in Bengaluru.

The Idea2PoC is a part of the country's first multi-sector start-up policy, unveiled by the state government to encourage entrepreneurs with funding to commercialise their innovation.

The start-ups with seed funding are Dr. Live Software (Rs 10 lakh), EasyKrishi (Rs 15 lakh), Lightmetrics (Rs 30 lakh), PiOctave Solutions (Rs 30 lakh), Geeksynergey Technologies (Rs 30 lakh), ispAgro Robotics (Rs 20 lakh), Astrome (Rs 30 lakh), Esyasoft (Rs 20 lakh), Geotraq Safety (Rs 45 lakh), NammaNimma Cycle Foundation (Rs 10 lakh), Sirena Technologies (Rs 48 lakh) and Selfdot Technologies (Rs 30 lakh).

"Though Bengaluru is the country's IT hub, we are seeing its start-up culture spreading to other areas, including agriculture, biotechnology, security, communications, robotics and gaming rapidly. Our aim is to mentor and help them to become self-sufficient," said IT & BT Principal Secretary Gaurav Gupta on the occasion.

Kartnataka Biotechnology and Information Techology Services (KBITS) Managing Director Salma K. Fahim said the state government was also targetting start-ups in emerging technologies such as animation, artificial intelligence, big data and virtual reality.

"These technologies can solve our long-standing problems, create hundreds of jobs and help in the 'Make in India' programme of the central and state governments," added Fahim.

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Puma Biotechnology (PBYI) Lifted to Buy By Research Firm Zacks – Insider Tradings

Wednesday, June 28th, 2017

Research Firm Zacks boosted Puma Biotechnology (NYSE:PBYI) from a hold recommendation to a buy recommendation in a study note released on Early Thur, Jun 8th. Research Firm Zacks presently has $89.00 price objective on the biopharmaceutical firms shares.

Several stock researchers also recently released study analysis regarding the company. Citigroup boosted Puma Biotechnology to a buy recommendation and fixed a $105.00 price objective on the company shares in a study report on Sunday, May 28th. Stifel Nicolaus reissued a buy recommendation and gave a $105.00 target price on the stock of Puma Biotechnology in a study report on early Mon, Jun 5th. J P Morgan Chase & Co reaffirmed an overweight recommendation and given a $89.00 target price on the stock of Puma Biotechnology in a study report on early Tue, Jun 6th. Royal Bank Of Canada upped their target price on the stock of Puma Biotechnology from $60.00 to $88.00 and issued the shares a sector perform recommendation in a analysis report on Tue, Jun 6th. Lastly, Cowen and Company boosted Puma Biotechnology from a neutral recommendation to an outperform recommendation and fixed a $91.00 price objective on the company shares in a study analysis published on early Thur, May 25th. 1 equity analyst has recommended the share with a sell recommendation, two have published a hold recommendation and six have issued a buy recommendation to The corporation. the share presently has a consensus rating of Buy and an consensus price target of $86.94.

According to Research firm Zacks, Puma Biotechnology Stocks soared quite recently following an FDA advisory committee recommended approval of its lead pipeline candidate, neratinib for the treatment of HER2-positive breast cancers. As a development-stage company, Puma does not have any approved product in its portfolio yet. Thus, The corporation is totally dependent on its lead candidate neratinib for growth. With the latest FDA panel win, the approval of neratinib seems highly likely. An approval would be a huge rise for The corporation issued the immense commercial possible in the recipient market. However, dependence on the successful development and of a single candidate May severely hurt the firms growth prospects in case of any adverse development or regulatory setback. stocks of the company have outperformed the industry in the past 52 week.

Puma Biotechnology (PBYI) started trading at 85.95 on Early Thur. the firms valuation is $3.18 B. the company has 50 day SMA of $59.74 and a two hundred SMA of $42.39. Puma Biotechnology has a 52 week low of $27.64 and a 52 week high of $92.00.

Puma Biotechnology (NYSE:PBYI) previously issued its earnings report on early Wed, May 10th. The biopharmaceutical business posted ($1.97) EPS for the period, reaching the Zacks average forecast of ($2.06) by $0.09. on consensus, financial stock experts expect that Puma Biotechnology to post ($8.50) EPS for the present financial year.

In other Puma Biotechnology news, large stockholder Adage Capital Partners Gp, L.L unloaded 507,128 stocks of the firms shares in a trade dated Mon, Jun 5th. The stock was unloaded at a price range of of $87.84, amounting $44,546,123.52. The information was declared in a document with the securities and exchange commission, which is accessible through this link. executive have unloaded a total of 1,990,088 stocks of company shares valued $157,553,113 in the previous 90 days. corporate executives has an ownership of 22.70% of the firms stock.

Hedge funds have lately adjusted their holdings of The corporation. Bank of Montreal Can bought a new stake in stocks of Puma Biotechnology during the Q1 worth at $195,000. Alambic Investment Management bought a new stake in stocks of Puma Biotechnology during the Q1 worth at $201,000. Parametric Portfolio Associates bought a new stake in stocks of Puma Biotechnology during the Q1 worth at $257,000. Perceptive Advisors bought a new stake in stocks of Puma Biotechnology in Q4 which is worth at $225,000. Lastly, Weiss Multi Strategy Advisers bought a new stake in stocks of Puma Biotechnology during the Q1 worth at $335,000. investment firms and many large funds has an ownership of 80.98% of the firms stock.

About Puma Biotechnology

Puma Biotechnology, is a biopharmaceutical company that focuses on the development and commercialization of products for the treatment of cancer. The corporation focuses on in-licensing the development and commercialization rights to over around three drug candidates, including PB272 (neratinib (oral)), PB272 (neratinib (intravenous)) and PB357.

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iShares Nasdaq Biotechnology Index Fund (IBB) Rating Reduced by Vetr To Keep – Insider Tradings

Wednesday, June 28th, 2017

IShares Nasdaq Biotechnology Index Fund (NASDAQ:IBB) was lowered by investment analysts at crowd sourced stock rating company Vetr from a buy recommendation to a hold recommendation in a research note released to investors and clients on early Mon, Jun 5th. Firm has a $307.00 PT on the financial services providers shares. Vetrs target price points a possible drop of 1.25% from the firms prior close.

IShares Nasdaq Biotechnology Index Fund (IBB) transacted up 1.443% through out intraday market trading on early Mon, topping $315.375. 899,883 stocks of the shares transacted hands. Companys 50 Day SMA is $293.14 and its 200 SMA is $286.87. iShares Nasdaq Biotechnology Index Fund has a 1 year low of $240.30 has a 1 year high of $316.00.

On the other hand, Credit Suisse Group boosted iShares Nasdaq Biotechnology Index Fund from a market weight recommendation to an overweight recommendation in a study on Tue, Mar 21st. The move was based on the current stock valulation.

Most recently the business also announced a periodic dividend, expected to be paid on early Fri, Jun 30th. Investors with a record date on Early Thur, Jun 29th will be given a $0.1768 dividend. The ex-dividend date of this dividend is Tue, Jun 27th. this indicates a $0.71 dividend on a yearly basis and a payout of of 0.23%.

Quite a few investment firms and many large funds have acquired or sold some of the position in IBB. Morgan Stanley upped its stake in iShares Nasdaq Biotechnology Index Fund by 16.3% in the Q1. Morgan Stanley has an ownership of 1,774,505 stocks of the financial services providers shares valued $520,408,000 after scooping up an extra 248,914 shares through out the quarter. JPMorgan Chase boosted its position in stocks of iShares Nasdaq Biotechnology Index Fund by 45.7% in the Q1. JPMorgan Chase has an ownership of 782,179 stocks of the financial services providers shares valued at $229,389,000 after scooping up an extra 245,458 shares through out the quarter. Alliancebernstein boosted its position in stocks of iShares Nasdaq Biotechnology Index Fund by 40.9% in the Q1. Alliancebernstein has an ownership of 481,442 stocks of the financial services providers shares valued at $141,192,000 after scooping up an extra 139,657 shares through out the quarter. PNC Financial Services Group boosted its position in stocks of iShares Nasdaq Biotechnology Index Fund by 1.0% in the Q1. PNC Financial Services Group has an ownership of 210,978 stocks of the financial services providers shares valued at $61,872,000 after scooping up an extra 2,112 shares through out the quarter. Lastly, Janney Capital Management boosted its position in stocks of iShares Nasdaq Biotechnology Index Fund by 34.6% in the Q1. Janney Capital Management has an ownership of 110,807 stocks of the financial services providers shares valued at $32,496,000 after scooping up an extra 28,503 shares through out the quarter. hedge fund investors and investment firms has an ownership of 69.06% of the firms stock.

About iShares Nasdaq Biotechnology Index Fund

IShares Nasdaq Biotechnology ETF (the Fund), formerly iShares Nasdaq Biotechnology Index Fund, is an exchange-traded fund (ETF). The Fund seeks investment data that correspond generally to the price and pay out performance of the NASDAQ Biotechnology Index (the Index). The Index contains securities of NASDAQ listed companies that are classified according to the Industry Classification Benchmark as either biotechnology or pharmaceuticals, which also meet other eligibility criteria determined by NASDAQ.

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Diabetes: J&J and Seventure Partners launch investment – European Biotechnology

Wednesday, June 28th, 2017

European venture capitalist Seventure Partners and Johnson & Johnson have invested US$12m in Israel-based DayTwo. Based on HbA1c, lifestyle factors and genetic analysis of the individual microbiome, the companys app analyses the individual microbiome to predict blood sugar responses to thousands of different foods.

Seventure Partners said it ran the investment through its Health for Life Capital investment vehicle, as part of a $12m series A fundraising.

DayTwo has exclusively licensed technology from Weizmann Institute to predict how a specific diet impacts the individual blood glucose level. After the companys app is fed with HbA1c results, lifestyle factors and sequence analyses of the individual microbiome, its machine-learning predictive algorithms provide personalised nutrition recommendations on a users smart device.

Seventure Partners announced its investment was made in syndication with Johnson & Johnson as well as historical investors. DayTwo wants to use the fresh capital to commercialise its product internationally beyond Israel and develop new products tailored for other user segments. According to DayTwo, currently, the app is marketed in Israel as a wellness product that targets highly-motivated consumers, giving them insight into how to manage the food choices that are best for them. The company is currently preparing the US market launch with the same purpose.

However, the companys ultimate goal is to additionally enter a higher-price market segment for its app: as a proven medical product that prevents or slows the development of diabetes. In February, DayTwo joined forces with J&J susidiary Janssen Biotech to develop personalised microbiome analysis for diabetes nutrition. The cooperation is designed to provide clinical data that will help DayTwo to submit the product for approval from the US Food and Drug Administration (FDA) and corresponding authorities in other countries.

According to Seventure Partners CEO Isabelle de Cremoux, DayTwo rounds out our microbiome portfolio. Current investments include French Enterome SA (microbiome modulator drugs, diagnostics and companion diagnostics), LNC (drug-probiotic and nutrition microbiome-modulator products), Maat Pharma (autologous microbiome transplant), TargEDys (bacteria for regulation of appetite) and Vedanta (drug-probiotic).

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Explore Innovations in Industrial Biotechnology at Upcoming Workshops – Newswise (press release)

Tuesday, June 27th, 2017

Newswise Industrial biotechnology scientists, educators, entrepreneurs and executives from around the globe will be convening on the University of California San Diego campus this summer to explore the latest advances and world-changing innovations heating up the white-hot field of industrial biotechnology with workshops in microbial fermentation and metabolic engineering.

UC San Diego Extension will host its annual Industrial Biotechnology Workshops on Aug. 14 through 18. Participants can attend the whole program or attend the workshops on microbial fermentation or metabolic engineering separately.

Now in its fifth year, this widely acclaimed educational event creates an informal, intimate environment for robust exchange of knowledge and ideas among world-class academic instructors and leaders of cutting-edge companies of every size from startup to mature, said Hugo Villar, associate dean of Professional & Continuing Education for UC San Diego Extension.

Whether from California or China, biotechnology professionals attending these workshops will have a front-row seat to learn about current developments and advanced scientific skills being used to solve some the worlds most difficult problems, Villar said.

Microbial Fermentation

For the past four years, the workshop focused primarily on microbial fermentation, which is the transformation of feedstocks, such as plant sugars, into useful products, like fuels, chemicals, beer or antibiotics, by bacteria, yeast, fungi or algae.

The Microbial Fermentation Workshop will be held Aug. 16 to 18. Participants will be introduced to the fundamental knowledge and practical skills needed to design, develop, optimize, control, scale-up, analyze and troubleshoot fermentation processes.

As one of just a handful of programs in the world that provide in-depth, practically oriented coursework in microbial fermentation, it is expected to draw participants from Connecticut to Croatia.

While workshop participants should have some basic knowledge and experience in fermentation, everyone from scientists to biotech business executives to graduate students could benefit from the microbial fermentation workshop.

This years program features some of the brightest minds in the field, including:

Jeff Lievense, senior advisor of Bioengineering & Technology, Genomatica;

Rachel Dutton, assistant professor of Molecular Biology, UC San Diego;

Michael Japs, senior director of Process Technology, Genomatica;

Jon Hansen, principal of New Leaf Biotech;

Jason Ryder, vice president, Process R&D, Hampton Creek; and

Karen Fortmann, senior research scientist, White Labs.

Five interactive case studies, including production of microbes for cheese and beer, will allow attendees to practice what they learn, while the Fermentation Firing Line segment will offer a lively, open ended forum for posing questions to the instructional team on fermentation-related topics.

In addition, everyone in attendance can participate in a tour of the global headquarters of White Labs, which produces yeast for beer making, and attend a hosted reception in its craft beer tasting room.

Metabolic Engineering

A new segment on metabolic engineering, which will run Aug. 14-15, will also be offered.

Recently named as one of the top 10 emerging technologies by the World Economic Forum, metabolic engineering focuses on the design and development of equipment and processes for manufacturing products such as agriculture, food, animal feed and pharmaceuticals.

Instructors joining the interactive course with case studies throughout the curriculum include:

John Pierce, MIT lecturer and former scientist at multinational firms BP and DuPont;

Adam Feist, project scientist, UC San Diego;

Ben Griffin, senior director, Microbial and Enzyme Engineering, Synthetic Genomics;

Jeff Lievense, senior advisor, Genomatica;

Jim Mills, chief technology officer, BioAmber, Inc.;

Bernhard Palsson, principal investigator, UC San Diego; and

Kristy Salmon, head of research, BP.

Those who attend the Metabolic Engineering segment are also invited to participate in a tour of the global headquarters of White Labs, which produces yeast for beer making, and attend a hosted reception in its craft beer tasting room.

Those interested in finding out more about the upcoming workshops can visit http://extension.ucsd.edu/industrialbiotech , call (858) 534-9353 or email unexbio@ucsd.edu.

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66m Life Sciences Fund focused on Germany and Benelux … – European Biotechnology

Tuesday, June 27th, 2017

Venture Capitalist Biogeneration Ventures has exceeded the target size of its life sciences fund BGV III through investments from the European Investment Banks InnovFin Equity Facility and the Dutch Venture Initiative II.

The third fund of the Dutch company now comprises 66m, 16 more than the BVG IIIs initial target size. Biogeneration did not provide figures about the exact financial contributions of its new investors but said that investments will focus on medtech, diagnostic and drug development companies in Germany and Benelux.

The new fund will build on the first two BGV funds which yielded some success for investors including a 1,55bn divestment of Dezima Pharma into Amgen and the 7bn exit of Acerta Pharma, the largest private exit in Europe in the biotech sector to date.

Four investments have already been made from BVG III into German immuno-oncology company Catalym, and Dutch companies Escalier Biosciences, Scenic Biotech and Varmx, working on autoimmune diseases, target discovery, and haematology, respectively.

Our third fund makes BGV amongst the largest life sciences funds dedicated to seed investments in Europe, said Edward van Wezel, Managing Partner. Over the last decade we have made over twenty investments in the European life sciences ecosystem. Weve observed an ever-increasing interest from pharma in acquiring innovations earlier. With this third closing we are significantly exceeding our target fund size and are delighted with the commitment of EIF and other new and existing investors in BGV III. We expect to reach the maximum fund size of EUR 75m before the end of 2017.

BGV operates as a joint venture with Forbion Capital Partners, providing access to the later stage perspective on early innovation and a global network of experts and pharma companies. The BGV team has broad experience in investment, life sciences, business development, and commercial operations. The team includes experienced biotech entrepreneurs as venture partners and advisors.

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