StemCell Therapy

A new grant will look at the effects of aging caused by antiviral therapies in individuals with HIV.

People living with HIV are fortunate that effective therapies are now available that dramatically reduce mortality for those infected with that virus. Despite the effects of antiviral therapy on longevity, people living with HIV are showing signs of accelerated aging.

University of Alabama at Birmingham College of Arts and Sciences Department of Biology Chair Steve Austad, Ph.D., received a National Institutes of Health five-year grant for $3.7 million to study the intersection of HIV and aging.

People with HIV using antiviral therapy are experiencing earlier onset of age-related diseases including heart disease, cancer and dementia. The grant through a collaboration of multiple institutions led by UAB, the University of Washington and Wake Forest University is designed to provide interdisciplinary training to researchers and clinicians in both HIV and aging biology. Investigators will use the knowledge gained from research working at the junction of aging and HIV biology to improve clinical treatment and care of people living with HIV.

Further, the grant will provide pilot grant support for projects involving molecular links between HIV infection and aging. Researchers will collaborate with the UAB Center for AIDS Research and the McKnight Brain Institute.

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$3.7 million grant awarded to UAB to study antiviral therapies and accelerated aging - The Mix

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